CN101390980B - External medicine for treating skin disease and preparation method thereof - Google Patents

External medicine for treating skin disease and preparation method thereof Download PDF

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CN101390980B
CN101390980B CN200810232922XA CN200810232922A CN101390980B CN 101390980 B CN101390980 B CN 101390980B CN 200810232922X A CN200810232922X A CN 200810232922XA CN 200810232922 A CN200810232922 A CN 200810232922A CN 101390980 B CN101390980 B CN 101390980B
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CN101390980A (en
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张人善
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Abstract

The invention discloses an external used medicine for curing dermatosis, which takes following raw materials as components: gypsum, wild chrysanthemum, honeysuckle, baical skullcap root, coptis root, rhubarb, amur corktree bark, sargentgloryvine stem, tree peony bark, bezoar, bear gall and muskiness; according to different characteristics of each Chinese traditional medicine, the components can be treated by smashing and extracting with adding water, can be added by carriers which can be pharmaceutically accepted, and can be made into medicament according to common preparation method; the medicine is considered as the innovative practice achievement under the guide of modernization theory of the Chinese Traditional Medicine, and firstly takes the gypsum as principal component for the preparation and is a multiple target medicine; the medicine has the advantages of unique preparation, simple manufacturing method, wide treatment range, obvious curative effect and secure usage; thus having fine application prospect and better social effect and economic benefit.

Description

Dermopathic external used medicine of a kind of treatment and preparation method thereof
Technical field
The present invention relates to the dermopathic external used medicine of a kind of treatment, particularly a kind of is the Chinese patent medicine of feedstock production with the Chinese herbal medicine, also relates to the preparation method of this medicine.
Background technology
Dermatosis is a kind of commonly encountered diseases, mainly contains dermatitis, rash, tinea, skin ulcer and scabies etc., and clinical manifestation is to occur macule, pimple, welt, tuberosity, pustule, cyst, ulcer etc. on the skin, and there are symptoms such as pruritus, pain, numbness, burn feeling in the affected part.Dermatosis mostly is stubborn disease, and usually the several years does not heal, and brings very big misery to the patient.About pathogeny, doctor trained in Western medicine is often thought by due to antibacterial, fungus or the viral infection; The traditional Chinese medical science is then thought and is attacked table or wind syndrome due to blood-deficiency so that disorder of QI and blood, blood do not become skin to form by rheumatism.
At present, to treating for skin disease Western medicine commonly used, not only cost an arm and a leg both at home and abroad, and mostly mixed steroid hormone in antibacterials, easily recurrence is easy to generate dependency and Drug resistance after the drug withdrawal, and life-time service produces more side effect to human body.Though also there are some to treat dermopathic Chinese patent medicine, because therapeutic effect is not fairly obvious, the patient still has to depend on some Western medicine.And the dermopathic Western medicine of existing treatment and Chinese patent medicine all can only treat one or more dermatosiss, has problems such as therapeutic domain is narrower, therapeutic effect is undesirable.
Therefore, give full play to the advantage of China's Chinese medicine, develop and a kind ofly treat the dermatosis wide ranges, effective Chinese patent medicine has crucial meaning.
Summary of the invention
In view of this, the objective of the invention is to overcome the deficiencies in the prior art, providing a kind of is the dermopathic external used medicine of treatment of feedstock production with the Chinese herbal medicine, has characteristics such as prescription uniqueness, simple, the many target treatment of preparation method, therapeutic domain be wide, evident in efficacy, safe in utilization.
Another object of the present invention is to provide the preparation method of this medicine.
Solution of the present invention is: the inventor is from realizing the modern guiding theory of Chinese medicine, and through Chinese medical theory research for many years and clinical practice, proposed following viewpoint: (1) traditional Chinese medical science is syndrome systematology science; (2) traditional Chinese medical science modernization should be developed into " disease is distinguished and controlled " of the combination of Chinese and Western medicine by the traditional Chinese medical science traditional " determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs ", further develops " eight guiding principles for diagnosis system biological medicine and pharmacology " of advanced stage again; (3) modernization of Chinese medicine should develop into " biconjugate medicine " with the simple traditional Chinese medical science " verification medicine " and doctor trained in Western medicine " to sick medicine " on traditional Chinese medical science modernization basis, promptly presses Chinese medicine monarch principle prescription, and the side's of making medicine had both met the card of the traditional Chinese medical science, again the disease of corresponding doctor trained in Western medicine; Again on " biconjugate medicine " basis, further develop " many target spots medicine ", promptly find the material base of tcm syndrome systematology earlier, on this material base, the generation of study of disease, development evolution process according to " biconjugate medicine " principle prescription, make every effort to reach many target treatments effect again, enlarge therapeutic domain, improve curative effect.Under above-mentioned theory instructed, the inventor had made big quantity research to dermatosis, and result of study shows that the dermatosis more than 90% belongs to the heat syndrome system, has common pathologic basis; On this basis, the inventor is the Therapeutic Principle to eliminate various heat syndrome reactions, to remove blood stasis and kill or suppress pathogenic microorganism, and the dermopathic many target spots medicine of treatment is developed in innovation.
Medicine of the present invention is the medicament of being made by following raw materials in portion by weight: 40~60 parts in Gypsum Fibrosum, 8~12 parts of Flos Chrysanthemi Indicis, 5~9 parts of Flos Loniceraes, 4~6 parts of Radix Scutellariaes, 4~6 parts of Rhizoma Coptidis, 4~6 parts of Radix Et Rhizoma Rhei, 4~6 parts of Cortex Phellodendris, 4~6 parts of Caulis Sargentodoxaes, 4~6 parts of Cortex Moutans, 1.6~2.4 parts of Calculus Boviss, 0.8~1.2 part of Fel Ursi, 0.008~0.012 part in Moschus.
Further, the weight portion proportioning of each raw material is: 45~55 parts in Gypsum Fibrosum, 9~11 parts of Flos Chrysanthemi Indicis, 6~8 parts of Flos Loniceraes, 4.5~5.5 parts of Radix Scutellariaes, 4.5~5.5 parts of Rhizoma Coptidis, 4.5~5.5 parts of Radix Et Rhizoma Rhei, 4.5~5.5 parts of Cortex Phellodendris, 4.5~5.5 parts of Caulis Sargentodoxaes, 4.5~5.5 parts of Cortex Moutans, 1.8~2.2 parts of Calculus Boviss, 0.9~1.1 part of Fel Ursi, 0.009~0.011 part in Moschus;
Further, the weight portion proportioning of each raw material is: 50 parts in Gypsum Fibrosum, 10 parts of Flos Chrysanthemi Indicis, 7 parts of Flos Loniceraes, 5 parts of Radix Scutellariaes, 5 parts of Rhizoma Coptidis, 5 parts of Radix Et Rhizoma Rhei, 5 parts of Cortex Phellodendris, 5 parts of Caulis Sargentodoxaes, 5 parts of Cortex Moutans, 1.99 parts of Calculus Boviss, 1 part of Fel Ursi, 0.01 part in Moschus;
Further, described medicament is ointment or cream;
Further, described medicament is an ointment.
Each raw material in the medicine of the present invention has following character and effect:
Gypsum Fibrosum is a Sulfates mineral anhydrite family Gypsum Fibrosum, the main hydrous calcium sulfate (CaSO that contains 42H 2O); Sweet in the mouth, suffering, property Great Cold; Attach to the lung and stomach meridians; Has the effect that clearing away heat-fire, relieving restlessness quench the thirst; Be used for hyperactivity of toxic heat, send out the speckle dermexanthesis, skin infection burst and do not hold back, eczema, burn due to hot liquid or fire etc.
Flos Chrysanthemi Indici is the dry capitulum of feverfew Herba Dendranthematis indici Chrysanthemum indicum L.; Bitter in the mouth, suffering, cold nature; Return liver, heart channel; Effect with heat-clearing and toxic substances removing; Be used for pyretic toxicity and pent up, ulcer sores, furuncle furuncle erysipelas, skin pruritus such as eczema etc.; Modern pharmacological research shows that the Flos Chrysanthemi Indici decoct has broad-spectrum antibacterial action, and the obvious anti-inflammatory and anti effect is arranged.
Flos Lonicerae is the dry flower of caprifoliaceae plant Radix Ophiopogonis Lonicera japonica Thunb. or the flower that band is just opened; Sweet in the mouth, cold in nature; Return lung, the heart, stomach warp; Has heat-clearing and toxic substances removing, the effect of wind-heat dissipating; Be used for pyretic toxicity carbuncle furuncle etc.; Modern pharmacological research shows that Flos Lonicerae has broad-spectrum antibacterial action, and its water decoction has obvious anti-inflammatory and anti and refrigeration function, and the water logging agent can suppress the various skin fungus, and extracting solution has stronger anti-endotoxin effect.
Radix Scutellariae is the dry root of labiate Radix Scutellariae Scutellaria baicalensis Georgi; Bitter in the mouth, cold in nature; Return lung, gallbladder, spleen, large intestine, small intestine meridian; Have heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive effect; Be used for hot carbuncle toxin etc.; Modern pharmacological research shows that the Radix Scutellariae decoct has wider antimicrobial spectrum, and multiple staphylococcus, streptococcus, bacillus, dermatophytes etc. are all had inhibitory action, in addition, and effects such as analgesic in addition, calmness.
Rhizoma Coptidis is the dry rhizome of ranunculaceae plant Rhizoma Coptidis Coptis chinensis Franch., Coptis deltoidea C.Y.Cheng et Hsiao Coptisdeltoidea C.Y.Cheng et Hsiao or Coptis Teeta Wall Coptis teeta Wall.; Bitter in the mouth, cold in nature; GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel; Effect with heat clearing and damp drying, eliminating fire and detoxication; Be used for the carbuncle furunculosis, skin eczema etc.; Modern pharmacological research shows that Rhizoma Coptidis has stronger inhibitory action to staphylococcus, streptococcus, anthrax bacillus etc., and the various skin fungus is also had certain inhibitory action, and the effect of the phagocytic activity of analgesic, antiinflammatory, enhancing leukocyte and reticuloendothelial system is arranged.
Radix Et Rhizoma Rhei is the dry root and rhizome of polygonum rheum palmatum Rheum palmatum L., Rheum tanguticum Rheumtanguticum Maxim.ex Balf. or Rheum officinale Rheum officinale Baill.; Bitter in the mouth, cold in nature; Return spleen, stomach, large intestine, liver, pericardium channel; Effect with purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation; Be used for pathopyretic ulcer, erysipelas and burn and scald etc.; Modern pharmacological research shows that Radix Et Rhizoma Rhei all has inhibitory action to multiple Grain-positive and negative bacteria.
Cortex Phellodendri is the dry bark of rutaceae wampee Phellodendron chinense Schneid.; Bitter in the mouth, cold in nature; Return kidney, urinary bladder channel; Have heat clearing and damp drying, pathogenic fire purging except that the effect of steaming, skin ulcer is treated in detoxifcation; Be used for beriberi, pathopyretic ulcer, eczema eczema, pudendal pruritus swelling of the vulva, pruritus etc.; Modern pharmacological research shows that the Cortex Phellodendri decoct all has inhibitory action to various bacteria and dermatophytes, and external can impel subcutaneous oozing of blood to absorb.
Caulis Sargentodoxae is the dry rattan of Lardizabalaceae plant Caulis Sargentodoxae Sargentodoxa Cuneata (oliv.) Rehd.et Wils.; Bitter in the mouth, property is flat; Return liver, large intestine channel; The effect of have heat-clearing and toxic substances removing, promoting blood circulation and stopping pain, dispeling the wind is used for abdominalgia with intestinal abscess, pathopyretic ulcer etc.; Modern pharmacological research shows that Caulis Sargentodoxae contains emodin, tannin etc., and its decoct has inhibitory action to staphylococcus aureus, group B streptococcus, escherichia coli, bacillus pyocyaneus etc., and water extract energy anticoagulant suppresses thrombosis.
Cortex Moutan is the root bark of ranunculaceae peony Paeonia suffrut icosa Andr.; The bitter in the mouth suffering, cold in nature; Go into the heart, liver, kidney channel; Has clearing away heat and cooling blood, the effect of blood circulation promoting competent silt; Be used for the maculae caused by violent heat pathogen dermexanthesis, carbuncle sore tumefacting virus.Modern pharmacological research shows, Cortex Moutan contains the former glycosides of Cortex Moutan (generating paeonol and Cortex Moutan phenolic glycoside behind the enzymolysis), peoniflorin, Radix Paeoniae phenol, volatile oil and plant sterol etc., paeonol is the main active in the Cortex Moutan, have effects such as anti-inflammation, calmness, analgesic, analgesia, spasmolytic, common pathogenic dermatophytes is all had inhibitory action.
Calculus Bovis is the dry cholelithiasis of bovid cattle Bos taurus domesticus Gmelin; Sweet in the mouth, cool in nature; GUIXIN, Liver Channel; Effect with heat-clearing and toxic substances removing, endogenous wind stopping relieving convulsion, waking up the patient from unconsciousness by dissipating phlegm; Be used for carbuncle furunculosis due to the pyretic toxicity pent-up etc.; Modern pharmacological research shows, Calculus Bovis has calmness, convulsion, analgesic, antiinflammatory, anti-infectious function.
Fel Ursi is the dry gallbladder of vertebrates Ursidae brown bear U rsus arctos Linnaeus, black bear Selenarctosthibetanus Cuvier; Bitter in the mouth, cold in nature; Return liver, gallbladder, heart channel; Effect with heat-clearing and toxic substances removing, endogenous wind stopping relieving convulsion, liver heat removing and eyesight improving; Be used for sore, carbuncle and painful swelling and swelling and pain of hemorrhoid etc.; Modern pharmacological research shows, Fel Ursi has certain detoxifcation, antibacterial, antiinflammatory, anti-allergic effects.
Moschus is the dry secretions in the ripe male body note capsule of animal in deer family woods Moschus moschiferous Moschus berezovskii Flerov, horse Moschus moschiferous Moschussifanicus Przewalski or former Moschus moschiferous Moschus moschiferus Linnaeus; Acrid in the mouth, warm in nature; Have the refreshment of having one's ideas straightened out, promoting blood circulation to restore menstrual flow, reducing swelling and alleviating pain, oxytocic effect; Be used for sore swollen toxin etc.; Modern pharmacological research shows, the Moschus anticoagulant, and antithrombotic has inhibitory action to staphylococcus aureus, escherichia coli etc.
The preparation method of medicine of the present invention may further comprise the steps:
A, take by weighing Calculus Bovis, Fel Ursi and Moschus, be ground into 300 order fine powders by described proportioning, standby;
B, take by weighing Gypsum Fibrosum, Flos Chrysanthemi Indici, Flos Lonicerae, Radix Scutellariae, Rhizoma Coptidis, Radix Et Rhizoma Rhei, Cortex Phellodendri, Caulis Sargentodoxae and Cortex Moutan by described proportioning, soak extraction, filter, filtrate is concentrated into the gross weight of all raw materials and equates, and is standby;
C, step a gained fine powder and step b gained concentrated solution mix homogeneously are got medicine, the weight portion proportioning by 15 parts of medicines, 85 parts in carrier adds pharmaceutically acceptable carrier again, and formulation method is made ointment routinely, packing, and sterilization, sealing is preserved.
Further, soak described in the step b and be extracted as 3 times, add the water of 2 times of amounts at every turn, under 80 ℃ of conditions of temperature, soak and extracted 12 hours.
The present invention has overcome in the existing Western medicine deficiencies such as medication dependency, Drug resistance and more toxic and side effects, existing treatment by Chinese herbs poor effect and the existing Drug therapy scope of using steroid hormone etc. to cause be narrower, has following outstanding substantive distinguishing features:
(1) different with the prescription theory of Chinese medicine, medicine of the present invention is to carry out prescription according to the Chinese medicine Modernization Theory " eight guiding principles for diagnosis system biological medicine and pharmacology " that the inventor creates, be that material base with traditional Chinese medical science dermal pathology opinion combines the original new drug of developing with Chinese medical discrimination and doctor trained in Western medicine differential diagnosis of diseases;
(2) principles of formulating prescriptions with Chinese medicine are different, medicine of the present invention is monarch drug first with the Gypsum Fibrosum, and its suffering is with expelling pathogenic factors from muscles for reducing heat, cold can clearing away heat-fire, can eliminate the various epidermis heat syndrome reactions that cause by pathogenic microorganism, physical factor, chemical factor or other factors, make skin recover normal;
(3) medicine of the present invention is many target spots medicine, utilizes the comprehensive function of the Chinese herbal medicine of respectively distinguishing the flavor of to treat various dermatosiss, and therapeutic domain is wide, all effective to present dermatosis more than 90%, the treatment total effective rate reaches more than 99%, and onset is rapid, evident in efficacy, except that the tinea cure rate is 65%, all the other various dermatosis cure rates reach 85%, and are non-stimulated to skin, no allergy and Drug resistance, life-time service safety can alleviate the patient suffering greatly, improves the quality of living;
(4) the wide and drug safety of medicine indication of the present invention, general public is judged with the oneself, just can use voluntarily according to medicine label and operation instruction, need not to open and write prescription or see a doctor to hospital by the medical professional, can save time, alleviate the country and the public's medical burden, solve problems such as public's difficulty and high cost of getting medical, the high cost of getting medical treatment;
(5) preparation method of medicine of the present invention is simple;
Therefore, medicine of the present invention has been obtained marked improvement, has a good application prospect, and can obtain good social benefit and economic benefit, is worth promoting.
The specific embodiment
In order to make the purpose, technical solutions and advantages of the present invention clearer, will be described in detail the preferred embodiments of the present invention below.
Embodiment one
The present embodiment medicine is the medicament of being made by following raw materials in portion by weight: Gypsum Fibrosum 40g, Flos Chrysanthemi Indici 8g, Flos Lonicerae 5g, Radix Scutellariae 4g, Rhizoma Coptidis 4g, Radix Et Rhizoma Rhei 4g, Cortex Phellodendri 4g, Caulis Sargentodoxae 4g, Cortex Moutan 4g, Calculus Bovis 1.6g, Fel Ursi 0.8g, Moschus 0.008g.
Embodiment two
The present embodiment medicine is the medicament of being made by following raw materials in portion by weight: Gypsum Fibrosum 45g, Flos Chrysanthemi Indici 9g, Flos Lonicerae 6g, Radix Scutellariae 4.5g, Rhizoma Coptidis 4.5g, Radix Et Rhizoma Rhei 4.5g, Cortex Phellodendri 4.5g, Caulis Sargentodoxae 4.5g, Cortex Moutan 4.5g, Calculus Bovis 1.8g, Fel Ursi 0.9g, Moschus 0.009g.
Embodiment three
The present embodiment medicine is the medicament of being made by following raw materials in portion by weight: Gypsum Fibrosum 50g, Flos Chrysanthemi Indici 10g, Flos Lonicerae 7g, Radix Scutellariae 5g, Rhizoma Coptidis 5g, Radix Et Rhizoma Rhei 5g, Cortex Phellodendri 5g, Caulis Sargentodoxae 5g, Cortex Moutan 5g, Calculus Bovis 1.99g, Fel Ursi 1.0g, Moschus 0.01g.
Embodiment four
The present embodiment medicine is the medicament of being made by following raw materials in portion by weight: Gypsum Fibrosum 55g, Flos Chrysanthemi Indici 11g, Flos Lonicerae 8g, Radix Scutellariae 5.5g, Rhizoma Coptidis 5.5g, Radix Et Rhizoma Rhei 5.5g, Cortex Phellodendri 5.5g, Caulis Sargentodoxae 5.5g, Cortex Moutan 5.5g, Calculus Bovis 2.2g, Fel Ursi 1.1g, Moschus 0.011g.
Embodiment five
The present embodiment medicine is the medicament of being made by following raw materials in portion by weight: Gypsum Fibrosum 60g, Flos Chrysanthemi Indici 12g, Flos Lonicerae 9g, Radix Scutellariae 6g, Rhizoma Coptidis 6g, Radix Et Rhizoma Rhei 6g, Cortex Phellodendri 6g, Caulis Sargentodoxae 6g, Cortex Moutan 6g, Calculus Bovis 2.4g, Fel Ursi 1.2g, Moschus 0.012g.
The various embodiments described above medicine can be made into ointment, and its preparation method may further comprise the steps:
A, take by weighing Calculus Bovis, Fel Ursi and Moschus, be ground into 300 order fine powders by described proportioning, standby;
B, take by weighing Gypsum Fibrosum, Flos Chrysanthemi Indici, Flos Lonicerae, Radix Scutellariae, Rhizoma Coptidis, Radix Et Rhizoma Rhei, Cortex Phellodendri, Caulis Sargentodoxae and Cortex Moutan by described proportioning, soak and extract 3 times, each water that adds 2 times of amounts, under 80 ℃ of conditions of temperature, soak and extracted 12 hours, filter, merge 3 times filtrate, be concentrated into the gross weight of all raw materials and equate, standby;
C, step a gained fine powder and step b gained concentrated solution mix homogeneously are got medicine, the weight portion proportioning by 15 parts of medicines, 85 parts in carrier adds pharmaceutically acceptable carrier again, and formulation method is made ointment routinely, packing, and sterilization, sealing is preserved.
Certainly, except that ointment, medicine of the present invention also routinely formulation method make cream, can reach goal of the invention equally.
The using method of medicine of the present invention is: external, and get and be applied to the affected part in right amount, every day 1-2 time.
Medicine of the present invention is the clinical use of nearly more than 30 ten thousand people's (inferior) through more than 30 years, and the treatment total effective rate reaches more than 99%, and except that the tinea cure rate is 65%, all the other various dermatosis cure rates reach 85%, and are non-stimulated to skin, no allergy and Drug resistance, life-time service safety.Below by the part clinical case, further specify the dermopathic good result of Drug therapy of the present invention.
Case one
Week certain, the woman gives birth to a skin infection near the vaginas in 1998, once hospitalization was three times, medical expenses amount to units up to ten thousand, i.e. recurrence after a period of time of at every turn leaving hospital, the back is with recovery from illness behind the medicine of the present invention three times.
Case two
Poplar, the woman, intravaginal pruritus decades, once how tame at home hospitalize for many years, radical cure, the back is with fully recovering behind the medicine first quarter moon of the present invention.
Case three
1992, Wu Jia town, Rongchang County, Chongqing City 100 multidigit children suffered from the unknown viral eczema of infectiousness, clinical appearance is bubbled earlier, and the symptom that whole body festers after several days once had the part patient to fail to respond to any medical treatment to big cities such as Chengdu, Chongqing, the back is with in the medicine of the present invention month, and all infants are all cured.
Case four
Zhao, the man gives birth to tinea for many years, and once multi-treatment did not effect a radical cure, and fully recover after near the bimester with medicine of the present invention in the back.
Case five
Rattan, the man suffers from surplus the whole body stubborn dermatitis 30 year, seeks medical advice in Chengdu once, how tame large hospitals such as Shanghai, Beijing, and therapeutic effect is all undesirable, and fully recovered after 1 year with medicine of the present invention in nineteen ninety-five in the back.
Case six
Xiong, the man, 12 years old, the right hand was injured by honeycomb briquet making making machine, and the five fingers point is badly mutilated, and hospital requires the amputation the five fingers, and the patient does not agree to fully recover after 1 year with medicine of the present invention in the back.
Case seven
Guo, tame three generations's whole body is very itched, at home multi-treatment invalid after, use medicine of the present invention to fully recover after half a year.
Explanation is at last, above embodiment is only unrestricted in order to technical scheme of the present invention to be described, although by invention has been described with reference to the preferred embodiments of the present invention, but those of ordinary skill in the art is to be understood that, can make various changes to it in the form and details, and the spirit and scope of the present invention that do not depart from appended claims and limited.

Claims (6)

1. treat dermopathic external used medicine for one kind, it is characterized in that: described medicine is the medicament of being made by following raw materials in portion by weight: 40~60 parts in Gypsum Fibrosum, 8~12 parts of Flos Chrysanthemi Indicis, 5~9 parts of Flos Loniceraes, 4~6 parts of Radix Scutellariaes, 4~6 parts of Rhizoma Coptidis, 4~6 parts of Radix Et Rhizoma Rhei, 4~6 parts of Cortex Phellodendris, 4~6 parts of Caulis Sargentodoxaes, 4~6 parts of Cortex Moutans, 1.6~2.4 parts of Calculus Boviss, 0.8~1.2 part of Fel Ursi, 0.008~0.012 part in Moschus.
2. the dermopathic external used medicine of treatment according to claim 1 is characterized in that: the weight portion proportioning of each raw material is: 45~55 parts in Gypsum Fibrosum, 9~11 parts of Flos Chrysanthemi Indicis, 6~8 parts of Flos Loniceraes, 4.5~5.5 parts of Radix Scutellariaes, 4.5~5.5 parts of Rhizoma Coptidis, 4.5~5.5 parts of Radix Et Rhizoma Rhei, 4.5~5.5 parts of Cortex Phellodendris, 4.5~5.5 parts of Caulis Sargentodoxaes, 4.5~5.5 parts of Cortex Moutans, 1.8~2.2 parts of Calculus Boviss, 0.9~1.1 part of Fel Ursi, 0.009~0.011 part in Moschus.
3. the dermopathic external used medicine of treatment according to claim 2 is characterized in that: the weight portion proportioning of each raw material is: 50 parts in Gypsum Fibrosum, 10 parts of Flos Chrysanthemi Indicis, 7 parts of Flos Loniceraes, 5 parts of Radix Scutellariaes, 5 parts of Rhizoma Coptidis, 5 parts of Radix Et Rhizoma Rhei, 5 parts of Cortex Phellodendris, 5 parts of Caulis Sargentodoxaes, 5 parts of Cortex Moutans, 1.99 parts of Calculus Boviss, 1 part of Fel Ursi, 0.01 part in Moschus.
4. according to claim 1 or the dermopathic external used medicine of 2 or 3 described treatments, it is characterized in that: described medicament is an ointment.
5. the preparation method of the dermopathic external used medicine of the described treatment of claim 4 is characterized in that: may further comprise the steps:
A, take by weighing Calculus Bovis, Fel Ursi and Moschus, be ground into 300 order fine powders by described proportioning, standby;
B, take by weighing Gypsum Fibrosum, Flos Chrysanthemi Indici, Flos Lonicerae, Radix Scutellariae, Rhizoma Coptidis, Radix Et Rhizoma Rhei, Cortex Phellodendri, Caulis Sargentodoxae and Cortex Moutan by described proportioning, soak extraction, filter, filtrate is concentrated into the gross weight of all raw materials and equates, and is standby;
C, step a gained fine powder and step b gained concentrated solution mix homogeneously are got medicine, the weight portion proportioning by 15 parts of medicines, 85 parts in carrier adds pharmaceutically acceptable carrier again, and formulation method is made ointment routinely, packing, and sterilization, sealing is preserved.
6. the preparation method of the dermopathic external used medicine of treatment according to claim 5 is characterized in that: soak described in the step b and be extracted as 3 times, add the water of 2 times of amounts at every turn, soak under 80 ℃ of conditions of temperature and extracted 12 hours.
CN200810232922XA 2008-10-27 2008-10-27 External medicine for treating skin disease and preparation method thereof Expired - Fee Related CN101390980B (en)

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