CN101351196B - 作为胶囊填充物的基于亲脂性载体的双重控释基质系统 - Google Patents

作为胶囊填充物的基于亲脂性载体的双重控释基质系统 Download PDF

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Publication number
CN101351196B
CN101351196B CN200680045615XA CN200680045615A CN101351196B CN 101351196 B CN101351196 B CN 101351196B CN 200680045615X A CN200680045615X A CN 200680045615XA CN 200680045615 A CN200680045615 A CN 200680045615A CN 101351196 B CN101351196 B CN 101351196B
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China
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weight
described capsule
drug
agent
release
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Expired - Fee Related
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CN200680045615XA
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Chinese (zh)
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CN101351196A (zh
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卡鲁纳卡尔·苏库鲁
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Pasin Rubber Co
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Banner Pharmacaps Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN200680045615XA 2005-10-26 2006-10-26 作为胶囊填充物的基于亲脂性载体的双重控释基质系统 Expired - Fee Related CN101351196B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US73051405P 2005-10-26 2005-10-26
US60/730,514 2005-10-26
PCT/US2006/041722 WO2007050724A2 (en) 2005-10-26 2006-10-26 Lipophilic vehicle-based dual controlled release matrix system as capsule fill

Publications (2)

Publication Number Publication Date
CN101351196A CN101351196A (zh) 2009-01-21
CN101351196B true CN101351196B (zh) 2013-07-03

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CN200680045615XA Expired - Fee Related CN101351196B (zh) 2005-10-26 2006-10-26 作为胶囊填充物的基于亲脂性载体的双重控释基质系统

Country Status (6)

Country Link
US (1) US8293270B2 (https=)
EP (1) EP1951208A2 (https=)
JP (2) JP5406529B2 (https=)
CN (1) CN101351196B (https=)
CA (1) CA2627351C (https=)
WO (1) WO2007050724A2 (https=)

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PT3335712T (pt) 2007-04-25 2025-10-23 Opko Renal Llc Método de tratamento e prevenção seguro e eficaz do hiperparatiroidismo secundário na doença renal crónica
PL2148661T3 (pl) 2007-04-25 2013-07-31 Cytochroma Inc Doustne kompozycje o kontrolowanym uwalnianiu zawierające związek będący witaminą D i woskowy nośnik
DK2148684T3 (da) 2007-04-25 2013-04-22 Cytochroma Inc Fremgangsmåde til behandling af vitamin D-insufficiens og -deficiens
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CN102046812A (zh) 2008-04-02 2011-05-04 赛特克罗公司 用于维生素d缺乏症和相关障碍的方法、组合物、用途和试剂盒
KR101702142B1 (ko) * 2008-10-22 2017-02-03 아유미 세이야쿠 가부시키가이샤 장관 흡수성을 개선하는 의약 조성물
PT2552484T (pt) 2010-03-29 2020-04-03 Opko Ireland Global Holdings Ltd Métodos e composições para redução dos níveis de parafróides
US10064960B2 (en) 2011-11-25 2018-09-04 Danmarks Tekniske Universitet Formulation of solid nano-sized particles in a gel-forming system
WO2014060856A1 (en) * 2012-10-16 2014-04-24 Wockhardt Limited Pharmaceutical compositions of diclofenac or salts thereof
WO2014060857A1 (en) * 2012-10-19 2014-04-24 Wockhardt Limited Pharmaceutical compositions of diclofenac or salts thereof
US10420729B2 (en) 2013-03-15 2019-09-24 R.P. Scherer Technologies, Llc Abuse resistant capsule
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 ｄ 방출 제형
US9326947B1 (en) 2014-02-28 2016-05-03 Banner Life Sciences Llc Controlled release fumarate esters
US10098863B2 (en) 2014-02-28 2018-10-16 Banner Life Sciences Llc Fumarate esters
AU2015222880B2 (en) 2014-02-28 2016-11-24 Banner Life Sciences Llc Controlled release enteric soft capsules of fumarate esters
US9636318B2 (en) 2015-08-31 2017-05-02 Banner Life Sciences Llc Fumarate ester dosage forms
US10772841B2 (en) 2014-04-07 2020-09-15 Patheon Softgels Inc. Opioid abuse-deterrent controlled release formulations
US10772842B2 (en) 2015-01-09 2020-09-15 Patheon Softgels Inc. Abuse-deterrent opioids
US10220047B2 (en) 2014-08-07 2019-03-05 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
MY198547A (en) 2016-03-28 2023-09-04 Opko Ireland Global Holdings Ltd Methods of vitamin d treatment
WO2017189621A1 (en) * 2016-04-26 2017-11-02 Symbiotic Health Inc. Stable macroemulsion for oral delivery of solubilized peptides, protein, and cellular therapeutics
US20210186915A1 (en) * 2018-03-15 2021-06-24 Cerecin Inc. Pharmaceutical compositions having high drug loadings of medium chain triglycerides and methods related thereto
CN113301884A (zh) * 2018-09-13 2021-08-24 夫特弗制药私人有限公司 非水性化疗口服悬浮液
US20210353573A1 (en) * 2018-10-08 2021-11-18 Chanelle Pharmaceuticals Manufacturing Ltd. A soft-gel capsule formulation, method of manufacture and use thereof
US11903918B2 (en) 2020-01-10 2024-02-20 Banner Life Sciences Llc Fumarate ester dosage forms with enhanced gastrointestinal tolerability

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US20020160041A1 (en) * 2001-02-21 2002-10-31 Jose Gutierrez-Rocca Controlled release pharmaceutical composition

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Also Published As

Publication number Publication date
WO2007050724A2 (en) 2007-05-03
CA2627351C (en) 2012-05-01
JP5406529B2 (ja) 2014-02-05
CN101351196A (zh) 2009-01-21
WO2007050724A3 (en) 2007-09-20
EP1951208A2 (en) 2008-08-06
JP2013216681A (ja) 2013-10-24
JP2009513657A (ja) 2009-04-02
US8293270B2 (en) 2012-10-23
US20070092560A1 (en) 2007-04-26
CA2627351A1 (en) 2007-05-03

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C56 Change in the name or address of the patentee

Owner name: BANNER LIFE SCIENCES INC.

Free format text: FORMER NAME: BANNER PHARMACAPS INC.

CP01 Change in the name or title of a patent holder

Address after: North Carolina

Patentee after: Banner Pharmacaps Inc

Address before: North Carolina

Patentee before: Banner Pharmacaps Inc

TR01 Transfer of patent right
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Effective date of registration: 20170920

Address after: North Carolina

Patentee after: Pasin Rubber Company

Address before: North Carolina

Patentee before: Banner Pharmacaps Inc

CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20130703

Termination date: 20191026