CN101347644B - Portable continuous renal replacement therapy equipment - Google Patents
Portable continuous renal replacement therapy equipment Download PDFInfo
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- CN101347644B CN101347644B CN2008101192658A CN200810119265A CN101347644B CN 101347644 B CN101347644 B CN 101347644B CN 2008101192658 A CN2008101192658 A CN 2008101192658A CN 200810119265 A CN200810119265 A CN 200810119265A CN 101347644 B CN101347644 B CN 101347644B
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- therapy apparatus
- displacement
- displacement pump
- liquid
- ultrafiltrate
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Abstract
The invention provides a portable and continuous kidney replacing therapy apparatus and a method for purifying blood. The therapy apparatus comprises a blood channel, a displacement liquid channel and an ultrafiltrate channel. The apparatus also comprises a first displacement pump, a second displacement pump and a controller, wherein, the first displacement pump is arranged in the displacement liquid channel, and liquid of fixed volume can be output per revolution; the second displacement pump is arranged in the ultrafiltrate channel, and liquid of fixed volume can be output per revolution; the controller calculates the input flow of the displacement liquid channel and the output flow of the ultrafiltrate channel in a volume metering method, controls the rotational speed of the first displacement pump and the second displacement pump and maintains the balance of the input flow and the output flow. The therapy apparatus of the invention can be used in the environments of turbulence, rocking and vibration, and the like, such as on the sea, and can be suitable for corrosion of salt-fog on the sea and a plurality of external power supplies.
Description
Technical field
The present invention relates to the hsempdiakysing systems in the medical apparatus and instruments, particularly relate to a kind of portable equipment for continuous renal replacement therapy and blood purification method.
Background technology
At the kidney medical domain, haemodialysis control unit generally has been used to give treatment to acute and chronic renal failure, and its design is fairly perfect, still, and the following shortcoming of conventional hemodialysis (CHD) machine ubiquity:
1) relies on the water source.The conventional hemodialysis (CHD) machine must be furnished with reverse osmosis water treatment system, continuously by high-pressure water pipe reverse osmosis water is delivered to haemodialysis control unit, therefore needs a large amount of water, must have competent water source.
2) can not move temporarily, can not carry out the other treatment of bed.The conventional hemodialysis (CHD) machine be unable to do without the water source owing to rely on reverse osmosis water treatment system, so be unable to do without Blood Purification Center or Laminar Airflow Room in the treatment, can not move patient's bedside to according to patient's the state of an illness, can not carry out the other treatment of bed.
3) can not carry the rescue of paying a home visit.Owing to adopted electromagnetic valve and counter balance pocket, the conventional hemodialysis (CHD) body is long-pending huge, the dependence water source, and any moving all is an engineering, therefore can not arbitrarily move, and more can not carry the rescue of paying a home visit.
CRRT (continuous renal replacement therapy, the equipment for continuous renal replacement therapy) is a kind of novel blood purification technology that developed recently gets up, in the absolute advantages that has demonstrated it aspect the treatment of crush syndrome, acute renal failure and even multiple organ dysfunction, therefore be a major progress in the emergency medicine.Though the CRRT machine has overcome the above defective of conventional hemodialysis (CHD) machine, does not rely on the water source, can carry out the other emergency treatment of bed,, still there is following defective in present known CRRT machine:
1) the still comparatively huge heaviness of volume is difficult for carrying;
2) adopt fan to carry out the heat radiation of cross-ventilation mode, at sea can be corroded very soon under the salt mist environment, can't on seagoing vessel, use.
3) do not have fixing and glissando, machine not only can not use under the environment that jolts, waves and shake but also damage easily.
4) of paramount importance is that because need the accurate balance of ultrafiltrate and displacement liquid, prior art has adopted accurate electronic scale respectively ultrafiltrate and displacement liquid to be monitored, and reaches the balance of ultrafiltrate, displacement liquid.But, liquid rock, violent change can take place in shown weight under the vibrations condition, so electronic scale can produce huge error, therefore existing CRRT machine jolt, wave and special environment such as vibrations under can not work fully, can't implement emergency aid and treatment.
And, need carry out the continuous blood purification treatment in the occasion of much rocking, jolting, and for example, the treatment of marine wound and sea water immersion.Marine wound merges sea water immersion and is different from general land wound, and its circumstance complication, the state of an illness are critical, very easily concurrent acute renal failure and multiple organs dysfunction, and as not given treatment in early days, mortality rate is high.Therefore, marine wound---the first aid of wound has become the difficult problem that medical circle is demanded urgently capturing under this special environment.The continuous blood purification treatment is to the peculiar traumatic condition of marine wound---and hypothermia, hyperosmotic dehydration, acid base imbalance, Water-Electrolyte disorder, inflammatory reaction, acute renal failure and MOFE all have tangible treatment effect, have absolute advantage.But, because the long-pending huge heaviness of known CRRT body is difficult for carrying, and machine itself is had relatively high expectations to stationarity, can not be under special environment work such as (rock on as ship, jolt), so the CRRT machine at sea a line implement to give treatment in early days, it can not bring into play due effect.
We just could not forget that in China " 5.12 " Wenchuan violent earthquake the extruding syndrome has unfeelingly seized the life of survivor in some earthquakes unexpectedly in addition! Highlighted the seriousness of its harm.Must adopt continuous blood purification to give treatment to the life that could effectively save the patient in early days for the extruding syndrome, this is that medical circle is confessed.But, aftershock constantly, under the environment condition of severe, existing CRRT machine cisco unity malfunction can't be brought into play due treatment effect.
Summary of the invention
The purpose of this invention is to provide a kind of portable equipment for continuous hsempdiakysing systems, can wait the special environment that jolts, waves and shake to use down at sea, solve the technical problem that existing CRRT machine can not use under above-mentioned special environment.
To achieve these goals, the embodiment of the invention provides a kind of portable equipment for continuous renal replacement therapy, comprises blood access, displacement liquid path and ultrafiltrate path, also comprises:
First displacement pump is arranged on described displacement liquid path, and revolution can be exported the liquid of fixed volume;
Second displacement pump is arranged on described ultrafiltrate path, and revolution can be exported the liquid of fixed volume;
Controller, the mode of measurement basis amount is calculated the input flow rate of described displacement liquid path and the output flow of described ultrafiltrate path, control the rotating speed of described first displacement pump and second displacement pump, keep the balance of described input flow rate and described output flow, avoid rocking, jolting by the mode of volume measurement, thereby can under the environment that rocks, jolts, work the influence of measuring accuracy.
Preferably, the bottom of shell of above-mentioned therapy apparatus is provided with a plurality of suckers, is used for fixing described therapy apparatus under the vibrations or the environment that jolts.
Preferably, in the above-mentioned therapy apparatus, described bottom of shell also is provided with a plurality of amortisseurs.
Preferably, in the above-mentioned therapy apparatus, described casing is the casing of sealing, and described casing has Heat Conduction Material, dispels the heat by described Heat Conduction Material.
Preferably, in the above-mentioned therapy apparatus, described casing is that light material is made, and described light material is aluminium alloy or titanium alloy.
Preferably, in the above-mentioned therapy apparatus, described displacement liquid path comprises balanced heater, and described balanced heater includes heat block and is arranged on the interior zigzag channel of described heat block, and described balanced heater heats all liq in the described zigzag channel by described heat block.
Preferably, in the above-mentioned therapy apparatus, also comprise, mate power supply more, can mate the multiple voltage standard.
Preferably, in the above-mentioned therapy apparatus, described controller is a Programmable Logic Controller, and connects a display.
In order to realize purpose of the present invention better, the present invention also provides a kind of continuous blood purification method, comprises the steps:
The mode of measurement basis amount is calculated the input flow rate of displacement liquid path; The mode of measurement basis amount is calculated the output flow of ultrafiltrate path; Control the rotating speed of second displacement pump of first displacement pump of described displacement liquid path and described ultrafiltrate path, keep the balance of described input flow rate and described output flow.
Preferably, in the above-mentioned blood purification method, also comprise: by amortisseur and sucker are set, reduce to jolt, wave the influence with vibration environment; By the housing of sealing is set, reduce the influence of marine salt mist environment.
There is following technique effect at least in the embodiment of the invention:
1) CRRT machine measurement basis amount mode of the present invention replaces the weight measurement mode of existing CRRT organic electronic scale, because the influence that the precision of volume measurement such as was not rocked, jolts at mal-condition, so use on the ambulance that hsempdiakysing systems of the present invention can be on seagoing vessel, exercise and in the special environment such as earthquake, and can ensure measuring accuracy.
2) CRRT machine of the present invention adopts balanced heater, by bloom all liq in the tortuous loop is carried out the equilibrium heating, can ensure turn back the fastest whole design temperatures that reach of liquid after the road heating of Via, effectively prevent the temperature inequality of liquid internal, in the continuous blood purification process that displacement liquid is had strict temperature requirement, be significant.
3) sealed enclosure housing of the present invention can effectively be resisted the influence of marine salt fog, and the casing housing has Heat Conduction Material, is not having also to carry out good heat radiation under the cross-ventilated situation.
4) casing of the present invention is provided with sucker and amortisseur, can effectively fix and damping, can adapt to the environment that waves, jolts on the seagoing vessel.
5) the present invention adopts the casing that light material is made, most of device is fixed on box house, again because the displacement pump volume much smaller than electromagnetic valve and counter balance pocket, so this CRRT body is long-pending little, in light weight, have portability, can make things convenient for medical personnel to carry use anywhere or anytime, this is for the huge heaviness of existing C RRT machine, be difficult to carrying, have the property of being convenient for carrying, can be transported on the ship that rocks fast or earthquake field, have the characteristic that conforms fast.
6) the present invention adopts many coupling power supplys, can adapt to the conventional power supply of 220V and the vehicle power of 12V (or 24V), can not have in the open air to use by the vehicle power power supply under the condition of conventional power supply.This has improved open-air adaptive capacity, helps the emergency rescue under environment such as earthquake.
In a word, the embodiment of the invention provides a kind of novel portable CRRT machine, this machine has simple and flexible, is convenient for carrying, advantage such as easy to operate, particularly can be applied to various complexity and unsettled special environment, at sea on (on the ship), the ambulance of exercising and implement urgent CRRT treatment under the seismic condition anywhere or anytime, for striving for rescue opportunity, save patient's life and play an important role.
Description of drawings
The structured flowchart of the CRRT machine that Fig. 1 provides for the embodiment of the invention;
The control principle figure of the CRRT machine that Fig. 2 provides for the embodiment of the invention;
The cabinet front view of the CRRT machine that Fig. 3 provides for the embodiment of the invention;
The cabinet left view of the CRRT machine that Fig. 4 provides for the embodiment of the invention;
The filter anchor clamps view that Fig. 5 provides for the embodiment of the invention;
The pipeline anchor clamps view that Fig. 6 provides for the embodiment of the invention;
The method flow diagram that Fig. 7 provides for the embodiment of the invention.
The specific embodiment
For the purpose, technical scheme and the advantage that make the embodiment of the invention is clearer, specific embodiment is described in detail below in conjunction with accompanying drawing.
The embodiment of the invention provides a kind of can the portable CRRT machine that use under the unsettled special environment condition such as rock, jolt.This CRRT machine is provided with the continuous blood purification system, and this continuous blood purification system comprises blood circuit, displacement liquid loop and ultrafiltrate loop, and, also comprise:
First displacement pump is arranged on described displacement liquid path, and revolution can be exported the liquid of fixed volume;
Second displacement pump is arranged on described ultrafiltrate path, and revolution can be exported the liquid of fixed volume;
Controller, the mode of measurement basis amount calculate the input flow rate of described displacement liquid path and the output flow of described ultrafiltrate path, control the rotating speed of described first displacement pump and second displacement pump, keep the balance of described input flow rate and described output flow.
The structured flowchart of the CRRT machine that Fig. 1 provides for the embodiment of the invention, as shown in Figure 1, three loops of CRRT machine, the firstth, the blood circuit that constitutes by blood pump, arterial blood pressure monitoring, transfusion filters, bubble monitoring and transducer potector.The secondth, by displacement liquid, aneroid monitoring, fluid infusion pump (i.e. first displacement pump 101), concentrate the displacement liquid loop that valve, heater, concentration monitor, pyrogen filter, bubble detection and venous pressure monitoring and pipeline constitute.The 3rd is by ultrafiltrate, the monitoring of leakage blood, concentrated valve, ultrafiltration liquid pump (i.e. second displacement pump 102) and dehydration pump, and the ultrafiltration pressure is monitored the ultrafiltrate loop that constitutes.Three flow dynamics systems that utilize four pumps (displacement liquid pump, blood pump and ultrafiltrate pump and dehydration pump) to constitute have been equipped with liquid heating, and temperature adjustment function is monitored venous pressure simultaneously, transmembrane pressure, air and leakage blood etc.
The control principle figure of the CRRT machine that Fig. 2 provides for the embodiment of the invention, as shown in Figure 2, the CRRT machine that the embodiment of the invention provides adopts the PLC programmable controller as the control system platform, joins line related, touch screen (really adopting screen for 6 inches, 36000 colors).Whole system is established 33 output controls of importing control and being no more than 23 with interior switching value input control and analog quantity altogether, and software and hardware is separately all disposed in each relevant control.
Because the hsempdiakysing systems of the embodiment of the invention is by the mode of PLC programmable controller measurement basis amount, to fluid infusion pump (i.e. first displacement pump 101), dehydration pump and ultrafiltration liquid pump (i.e. second displacement pump 102) are controlled, the turnover amount balance of the ultrafiltrate of energy assurance output and the displacement liquid of input, because it is stable that liquid capacity all keeps under various environment, so, in hsempdiakysing systems of the present invention, the turnover amount balance of ultrafiltrate and displacement liquid is not subjected to the influence of environmental stability, the present invention not only can be under the steady environment in land operate as normal, especially, also can rock, operate as normal under the unsettled special environment such as jolt, for example, the CRRT machine of the embodiment of the invention at sea (on the ship) is implemented urgent CRRT treatment anywhere or anytime, for striving for rescue opportunity, save patient's life and brought into play important effect.
In addition, in order better to adapt to the environment that jolts and rock, the bottom of shell of the therapy apparatus of the embodiment of the invention is provided with a plurality of suckers, is used for fixing described machine under the vibrations or the environment that jolts.Described bottom of shell also is provided with a plurality of amortisseurs, so that the impulse force of damping vibration.And transfusion filters and pipeline etc. are furnished with fixture and are fixed on the casing, can not be shifted because of rocking.
The casing of embodiment of the invention therapy apparatus is the casing of sealing, described casing has Heat Conduction Material, dispel the heat by described Heat Conduction Material, this is because traditional C RRT machine all is to dispel the heat by fan, and the fan heat radiation can produce cross-ventilation, and machine will soon be corroded by the salt fog at sea, and sealed enclosure housing of the present invention, can effectively resist the influence of marine salt fog, and the casing housing has heat conductivility, do not having also to carry out good heat radiation under the cross-ventilated situation.Described casing is that light material is made, and described light material is aluminium alloy or titanium alloy, helps weight reduction, is convenient to carrying.
In addition, the embodiment of the invention is at the balanced heater of described displacement liquid channel setting, described balanced heater includes heat block and is arranged on the interior zigzag channel of described heat block, described balanced heater heats all liq in the described zigzag channel by described heat block, because heat block and zigzag channel have strengthened the heating surface (area) (HS of liquid and have reduced heat time heating time, so equilibrium that can be the fastest heating.Wherein, heat block can be thermal conductive metallic materials such as steel, aluminium.
The embodiment of the invention also is provided with many coupling power supplys, can mate the multiple voltage standard, the vehicle-mounted voltage of 220v common voltage and 12v (24V) for example, therefore can not have in the open air to use vehicle power to power under the situation of regular power supply, this has improved open-air adaptive capacity, helps the emergency rescue under environment such as earthquake.
The cabinet front view of the CRRT machine that Fig. 3 provides for the embodiment of the invention, as Fig. 3, embodiment of the invention casing is provided with display screen 301 and a plurality of button 302, and this display screen and button and described PLC programmable controller join.
Described transfusion filters in the blood access of the embodiment of the invention, blood pump, first bubble monitoring member, and the pyrogen filter outside the blood access is fixed on the casing outside of described hsempdiakysing systems, with easy disassembly, all the other devices are installed in the casing inside of described hsempdiakysing systems.And as shown in Figure 4, transfusion filters 401 and pipeline etc. are furnished with fixture and are fixed on the casing, can not be shifted because of rocking.The fixture of transfusion filters as shown in Figure 5, the fixture of pipeline is as shown in Figure 6.
In a word, the volume of the portable CRRT machine of the embodiment of the invention is little, use is flexible, easy to carry, operation is simple and easy, not only can use at the steady environment in general land, particularly can operate as normal under the special environment such as rock, jolt, for medical personnel's timely rescue patient under all difficulties environment provides guarantee, brought into play important effect for saving patient's life.
In addition, the embodiment of the invention also provides a kind of continuous blood purification method, and the method flow diagram that Fig. 7 provides for the embodiment of the invention as figure, comprises the steps:
Step 703 is controlled the rotating speed of second displacement pump of first displacement pump of described displacement liquid path and described ultrafiltrate path, keeps the balance of described input flow rate and described output flow.
In addition, can also comprise:, reduce to jolt and the influence of vibration environment by amortisseur and sucker are set; By the housing of sealing is set, reduce the influence of marine salt mist environment.
The following environmental condition that can be suitable for for the portable CRRT machine of the embodiment of the invention:
1, ambient temperature, humidity requirement:
Ambient temperature :+5 ℃～+ 55 ℃
Relative humidity :≤95%
2. tilt to wave requirement:
Can and wave 22.5 in all directions inclination., cycle 10s: and vertical direction linear acceleration ± 9.8m/s
2The time operate as normal.
Or 6 grades below the sea situation: when degree of waving＜10 were spent, machinery equipment can run well.
6 grades more than the sea situation: when degree of waving＞10 were spent, machinery equipment was not damaged.
Annotate: vertical and horizontal tilt might take place simultaneously, and the value at armarium inclination angle is meant the angle requirement that equipment does not damage.
3. can bear the vibrations that means of transport produced such as normal operation of boats and ships and automobile:
Vibration parameters: general place---2.0Hz～13.2Hz, amplitude ± 1mm, 13.2Hz～100Hz, acceleration ± 0.7g.
4. voltage and frequency fluctuation:
Steady state voltage+6～-10%, frequency ± 5; Transient voltage ± 20%, recovery time 1.5s; Instantaneous frequency ± 10%, recovery time 5s.
5. harmonic wave:
Can be not more than operate as normal under 5% the situation at the harmonic components of power supply.
6. can be in humid air, salt fog, mist of oil and mycete environment operate as normal and depositing.
As from the foregoing, there is following technique effect at least in the embodiment of the invention:
1) CRRT machine measurement basis amount mode of the present invention replaces the weight measurement mode of existing CRRT organic electronic scale, because the influence that the precision of volume measurement such as was not rocked, jolts at mal-condition, so use on the ambulance that hsempdiakysing systems of the present invention can be on seagoing vessel, exercise and in the special environment such as earthquake, and can ensure measuring accuracy.
2) CRRT machine of the present invention adopts balanced heater, by bloom all liq in the tortuous loop is carried out the equilibrium heating, can ensure turn back the fastest whole design temperatures that reach of liquid after the road heating of Via, effectively prevent the temperature inequality of liquid internal, in the continuous blood purification process that displacement liquid is had strict temperature requirement, be significant.
3) sealed enclosure housing of the present invention can effectively be resisted the influence of marine salt fog, and the casing housing has Heat Conduction Material, is not having also to carry out good heat radiation under the cross-ventilated situation.
4) casing of the present invention is provided with sucker and amortisseur, can effectively fix and damping, can adapt to the environment that waves, jolts on the seagoing vessel.
5) the present invention adopts the casing that light material is made, most of device is fixed on box house, again because the displacement pump volume much smaller than electromagnetic valve and counter balance pocket, so this CRRT body is long-pending little, in light weight, have portability, can make things convenient for medical personnel to carry use anywhere or anytime, this is for the huge heaviness of existing C RRT machine, be difficult to carrying, have the property of being convenient for carrying, can be transported on the ship that rocks fast or earthquake field, have the characteristic that conforms fast.
6) the present invention adopts many coupling power supplys, can adapt to the conventional power supply of 220V and the vehicle power of 12V, can not have in the open air to use by the vehicle power power supply under the condition of conventional power supply.This has improved open-air adaptive capacity, helps the emergency rescue under environment such as earthquake.
The above only is a preferred implementation of the present invention; should be pointed out that for those skilled in the art, under the prerequisite that does not break away from the principle of the invention; can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.
Claims (8)
1. a portable equipment for continuous renal replacement therapy comprises blood access, displacement liquid path and ultrafiltrate path, it is characterized in that, also comprises:
First displacement pump is arranged on described displacement liquid path, and revolution can be exported the liquid of fixed volume;
Second displacement pump is arranged on described ultrafiltrate path, and revolution can be exported the liquid of fixed volume;
Controller, the mode of measurement basis amount is calculated the input flow rate of described displacement liquid path and the output flow of described ultrafiltrate path, control the rotating speed of described first displacement pump and second displacement pump, keep the balance of described input flow rate and described output flow, avoid rocking, jolting by the mode of volume measurement, thereby can under the environment that rocks, jolts, work the influence of measuring accuracy.
2. therapy apparatus according to claim 1 is characterized in that the bottom of shell of described therapy apparatus is provided with a plurality of suckers, be used for jolt, wave with vibration environment under fix described therapy apparatus.
3. therapy apparatus according to claim 2 is characterized in that described bottom of shell also is provided with a plurality of amortisseurs.
4. therapy apparatus according to claim 2 is characterized in that, described casing is the casing of sealing, and described casing has Heat Conduction Material, dispels the heat by described Heat Conduction Material.
5. therapy apparatus according to claim 2 is characterized in that, described casing is that light material is made, and described light material is aluminium alloy or titanium alloy.
6. therapy apparatus according to claim 1, it is characterized in that, described displacement liquid path comprises balanced heater, described balanced heater includes heat block and is arranged on the interior zigzag channel of described heat block, and described balanced heater heats all liq in the described zigzag channel by described heat block.
7. according to any described therapy apparatus in the claim 1 to 6, it is characterized in that, also comprise, mate power supply more, can mate the multiple voltage standard.
8. therapy apparatus according to claim 7 is characterized in that described controller is a Programmable Logic Controller, and connects a display.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2008101192658A CN101347644B (en) | 2008-09-01 | 2008-09-01 | Portable continuous renal replacement therapy equipment |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2008101192658A CN101347644B (en) | 2008-09-01 | 2008-09-01 | Portable continuous renal replacement therapy equipment |
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| CN101347644A CN101347644A (en) | 2009-01-21 |
| CN101347644B true CN101347644B (en) | 2010-06-09 |
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Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2532081T3 (en) * | 2012-03-28 | 2015-03-24 | Gambro Lundia Ab | Device for extracorporeal blood treatment |
| CN102895711A (en) * | 2012-10-29 | 2013-01-30 | 王雪 | Device for continuous renal replacement therapy (CRRT) |
| CN102961790A (en) * | 2012-11-14 | 2013-03-13 | 王雪 | Continuous renal replacement therapy device |
| WO2015007596A1 (en) | 2013-07-15 | 2015-01-22 | Gambro Lundia Ab | Relative pump calibration for ultrafiltration control in a dialysis apparatus |
| CN104470553B (en) | 2013-07-15 | 2017-02-22 | 甘布罗伦迪亚股份公司 | Individual Pump Calibration For Ultrafiltration Control In A Dialysis Apparatus |
| CN105999451A (en) * | 2016-06-17 | 2016-10-12 | 中国人民武装警察部队后勤学院附属医院 | Portable blood purifier for field operations |
| JP6998112B2 (en) * | 2016-09-12 | 2022-01-18 | 日機装株式会社 | Blood purification device |
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| US5470483A (en) * | 1993-03-22 | 1995-11-28 | Hospal Industrie | Device and method for controlling the balance of fluids in an extracorporeal blood circuit |
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| EP0722744A1 (en) * | 1995-01-19 | 1996-07-24 | Ube Industries, Ltd. | Apparatus for continous blood purification |
| CN1692954A (en) * | 2005-03-11 | 2005-11-09 | 暨南大学 | Fluid-balancing liquid-supplying device and its application |
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