CN102895711A - Device for continuous renal replacement therapy (CRRT) - Google Patents
Device for continuous renal replacement therapy (CRRT) Download PDFInfo
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- CN102895711A CN102895711A CN2012104222435A CN201210422243A CN102895711A CN 102895711 A CN102895711 A CN 102895711A CN 2012104222435 A CN2012104222435 A CN 2012104222435A CN 201210422243 A CN201210422243 A CN 201210422243A CN 102895711 A CN102895711 A CN 102895711A
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Abstract
The invention relates to a device for continuous renal replacement therapy (CRRT). The device comprises a blood loop, a blood purifier, a blood pump, a dialysate loop, a dialysate pump, a controller and a flow monitor; wherein the controller is used for adjusting a solution supply pump or a dewatering pump or uttering an alarm according to results of the flow monitor in monitoring of the dialysate loop. The problem that the accuracy of a CRRT machine in a volumetric metering technology is affected by multiple factors can be solved, and the constant and precise liquid flow can be ensured in the dialysate loop.
Description
Technical field
The present invention relates to a kind of field of medical technology, particularly a kind of continuous kidney replacement therapy device.
Background technology
Since Kramer doctor in 1977 at first will continue arteriovenous hemofiltration (CAVH) be applied to clinical since, continuous renal replacement therapy (Continuous Renal Replacement Therapy, CRRT) technology has obtained rapidly development, and its application in the critical illness patient is considered to one of impressive progress of ICU in recent years.
So-called CRRT (being continuous renal replacement therapy) is the english abbreviation of continuous kidney alternative medicine.Have another name called CBP (continue blood purification); Bedside hemo-filtration.Definition is to adopt 24 hours every days or a kind of long-time near 24 hours, and continuous extracorporeal blood purifies therapy to substitute impaired renal function.
A kind of continuous renal replacement therapy (CRRT) clinical practice target is to remove excess moisture in the body, removes internal metabolism refuse, poisonous substance, corrects Electrolyte imbalance, guarantees nutritional support, promotes graft function and removes various cytokines, inflammatory mediator.Can be used for: various cardiovascular functioies unsettled, Metabolism or companion cerebral edema acute and chronic renal failure, and Multiple Organ Dysfunction Syndrome, adult respiratory distress syndrome, crush syndrome, acute necrotizing pancreatitis, chronic heart failure, hepatic encephalopathy, the treatment of medicine and toxic poisoning etc.Continuous blood purification is a kind of New Blood purification techniques that grows up on the basis of hemodialysis in recent years, be the important means of critical patient treatment, but existing continuous blood purification machine also exists a lot of shortcomings.
The most crucial key technology of renal replacement therapy (CRRT) machine is control and the monitoring of fluid balance precision and liquid dehydration precision continuously, and the fluid balance precision of a kind of continuous kidney replacement therapy (CRRT) machine is divided into two kinds with the control technology of dehydration precision on the Present Domestic market: liquid weight measurement technology and liquid capacity measurement technology.
The weight metering technology is by the electronic-weighing components and parts, such as electronic balance, and the weight of direct weighing displacement liquid and waste liquid, thus realize the control of liquid turnover balance with the dehydration precision; The weight metering technology can directly be measured the actual weight of liquid, but because electronic balance requires just can carry out accurate measurement stable without under the environment that rocks, therefore in the situation for the treatment of environmental change, as all using on the vehicles such as earthquake relief work scene, ambulance, therefore adopt a kind of continuous renal replacement therapy (CRRT) of weight metering mode to be very restricted in environment for use.
In order to overcome the restriction of environment for use, existing a kind of continuous renal replacement therapy (CRRT) all adopts the volume measurement technology to realize control and the monitoring of fluid balance precision and liquid dehydration precision.The plunger displacement pump that so-called volume measurement refers to fix by cavity volume is as liquid driving device, the volume measurement technology by the every action of record plunger once, the liquid volume that flows out all is the mode of fixing, and realizes the control to fluid flow, because need not to be subjected to the restriction of environment for use.But, adopt a kind of continuous renal replacement therapy (CRRT) of volume measurement technology although be not subjected to the restriction of environment for use, but it can not directly measure the flow accuracy of liquid, calculates control but carry out flow by the mode of indirect measurement, has birth defect.That is to say, the volume measurement technology has determined that from its operation principle it can not directly measure the turnover amount of liquid, but by the monitoring displacement pump mechanical action number of times and cycle realize, think that the plunger volume moves the liquid capacity that flows out at every turn and all fixes, but in the actual use procedure, a lot of conditional decisions the vessel volume volume that fixedly is not equal to the liquid outflow fix.
The plunger displacement pump of existing volume measurement can be divided into two kinds of A, B on structure, category-A is the plunger displacement pump of importing and exporting with check valve, and this category-A pump is owing to import and export and have check valve, therefore liquid one-way flowing when plunger moves, but there are some problems in this category-A pump:
(1) these category-A pump import and export check valve core parts are made by rubber or silica gel material, produce the material fatigue aging behind the life-time service, cause check valve to return action not exclusively, cause leak of liquid to produce error;
(2) the action performance level of this category-A check valve is determined by inlet and outlet pressure, when the pressure of pump import and export changes, can cause the check valve action not exclusively to cause error, so the precision of category-A plunger displacement pump is received the direct impact of pump inlet and outlet pressure;
(3) when having small foreign material to flow through pump with liquid, can hang on the check valve, when there are small foreign material on the check valve surface, can cause check valve to move and produce larger error fully.
Category-B is rotary-plunger pump, this category-B pump and this category-A pump configuration are similar, this category-B pump housing part is made of cylinder sleeve and plunger, two passages of turnover are arranged on the cylinder sleeve, the plunger front end is semicolumn, carry out in the action clockwise before and after the plunger or be rotated counterclockwise, the semicolumn piston cooperates the anglec of rotation to realize the function of liquid unidirectional cutoff.Such plunger displacement pump has following shortcoming:
(1) precision of this category-B pump is affected by pump speed.The sealing of this category-B pump housing realizes that by the water seal effect between plunger and the cylinder sleeve namely when plunger action reached certain speed, the slit between plunger and the cylinder sleeve produced water membrane, can realize the effect of liquid seal.But when rotating speed cross when low or inside cavity pressure when changing fast the water seal effect disappear, cause liquid to flow out cavity by the slit, the cubical content that flows through pump diminishes, and when revolution speed is too fast, can produce cavitation effect, namely when plunger withdrawal was too fast, liquid can't in time flow in the cavity, cause the instantaneous negative pressure of cavity, make the gas effusion liquid that is dissolved in the liquid, save bit by bit a large amount of gases in the cavity, cause serious flow error;
(2) affected by inlet and outlet pressure very obvious for this category-B pump, machine exterior connects the height of liquid bag or fluid path whether smooth and easy degree all directly exerts an influence to precision in the therapeutic process, and because this pump precision is affected by outlet pressure also, the pressure of each fluid path is subjected to the impact of blood clotting degree and patient body condition to a great extent in therapeutic process, therefore can't guarantee that the delivery side of pump constant pressure is constant, cause the uncertainty of flow error;
(3) this category-B pump is owing to construction features, and therefore effectively monitoring means only has the action frequency of judging plunger by the action frequency of monitoring rotary part, infers the flow of pump with this, and directly therefore the actual flow of monitoring liquid exists hidden trouble;
(4) slit is very little between this category-B pump plunger and the cylinder sleeve, minute impurities and liquid crystalization can cause all that plunger and cylinder sleeve are stuck can't to rotate, need pump housing dismounting rear with just melting after the pure water long period of soaking after stuck, a kind of continuous renal replacement therapy (CRRT) that this technology is used in present market is not stuck in order to guarantee such pump, need to be full of liquid in the maintenance machine, the cavity and the import and export that are pump have liquid to seal up for safekeeping, but there is potential safety hazard in this way, do not meet the developing direction of blood purification hygienic requirements, and liquid does not run off still after can not guaranteeing the machine long preservation.
In a word, existing a kind of continuous renal replacement therapy (CRRT) adopts the volume measurement technology at present, its plunger pump structure is complicated, the volume precision is subject to various factors and because directly measuring flow variation of control system, only calculate flow by the action of monitoring plunger, therefore when flow error produces, system still calculates that with action frequency flow will cause very large error, only have when plunger causes the action of pump frame for movement to change because of mechanical or other factors, system just can judge, therefore in the face of flow error, existing CRRT machine can't in time react and adjust, and has larger potential safety hazard.
How a kind of continuous kidney replacement therapy device (CRRT) is provided, can solves the prior art problem, become the technical problem that needs to be resolved hurrily.
Summary of the invention
The technical problem to be solved in the present invention is how a kind of continuous kidney replacement therapy device is provided, and can directly measure fluid flow and change, by the operating frequency of measurement result control pump.
For solving the problems of the technologies described above, the invention provides a kind of continuous kidney replacement therapy device, comprising: blood circuit, blood purification, blood pump, dialysis fluid circuit, dialysis liquid pump, controller and flow monitor; Described blood circuit comprises blood sampling loop and blood back loop; Described blood purification is connected between described blood sampling loop and the described blood back loop; Described blood pump is arranged on the described blood sampling loop, is used for driving blood flowing on described blood sampling loop; Described dialysis fluid circuit comprises fluid infusion loop and dehydration loop; Described fluid infusion loop is connected with described blood sampling loop; Described dehydration loop is connected with described blood purification; Described dialysis liquid pump comprises fluid infusion pump and dehydration pump; Described fluid infusion pump is arranged on described fluid infusion loop, and described dehydration pump is arranged on the described dehydration loop; Described flow monitor is arranged on described fluid infusion loop and the described dehydration loop; Be used for the Real-Time Monitoring fluid flow, and monitoring result is sent to described controller; Described controller is regulated described fluid infusion pump and dehydration pump according to the result of described flow monitor monitoring or is reported to the police.
Preferably, described flow monitor is micro flow sensor.
Preferably, further comprise: heater, be arranged on the described fluid infusion loop, adopt thin-walled pressure vessel type structure; Described heater comprises and adds heat passage, and liquid enters by the liquid inlet that is arranged on described heater below, and behind the described heater of flowing through, the liquid outlet that is arranged by described heater top is transferred in the described blood back loop.
Preferably, described heater further comprises: the discharge opeing path, liquid is discharged by the liquid outlet that described heater below arranges.
Preferably, described heater further comprises: liquid level detector, be arranged on described heater top, and for detection of the described liquid level that adds liquid in the heat passage, and testing result sent to described controller.
Preferably, described heater further comprises: Temperature Detector, be arranged on the liquid outlet place of described heater top, and for detection of the described temperature that adds liquid in the heat passage, and testing result is sent to described controller.
Preferably, described heater further comprises: temperature switch, be arranged on the described heater, and described controller is controlled described temperature switch according to described temperature detection result.
Preferably, further comprise: reserve battery is positioned on the described controller.
Preferably, the material of described therapy equipment is the highstrenghtpiston.
The invention provides a kind of continuous kidney replacement therapy system, comprising: blood circuit unit, blood purification unit, blood pump unit, dialysis fluid circuit unit, dialysis liquid pump unit, control unit and flow monitoring unit;
Described blood circuit unit comprises blood sampling loop subelement and blood back loop subelement;
Described blood purification unit is connected between described blood sampling loop subelement and the described blood back loop subelement;
Described blood pump unit is arranged on the described blood sampling circuit units, is used for driving blood flowing in the subelement of described blood sampling loop;
Described dialysis fluid circuit unit comprises fluid infusion loop subelement and dehydration loop subelement; Described fluid infusion loop subelement is connected with described blood sampling loop subelement; The described blood purification of described dehydration loop subelement unit connects;
Described dialysis liquid pump unit comprises fluid infusion pump subelement and dehydration pump subelement; Described fluid infusion pump subelement is arranged on the subelement of described fluid infusion loop, and described dehydration pump subelement is arranged on the described dehydration loop subelement;
Described flow monitoring unit is separately positioned on described fluid infusion loop subelement and the described dehydration loop subelement; Be used for the Real-Time Monitoring fluid flow, and monitoring result is sent to described control unit;
Described control unit is regulated described fluid infusion pump subelement and dehydration pump subelement according to the result of the described flow monitor monitoring of receiving or is reported to the police.
Compared with prior art, characteristics of the present invention are:
A kind of continuous kidney replacement therapy device provided by the invention, employing is independent of the effusion meter control technology of weight metering technology and volume measurement technology, directly monitor the flow of liquid in the dialysis fluid circuit by being arranged on flow monitor in the dialysis fluid circuit, described controller is regulated the rotating speed of dialysis liquid pump according to monitoring result, the CRRT machine precision that had both solved the volume measurement technology is subjected to various factors, guarantee that the constant of fluid flow is with accurate, overcome the not high technical barrier of existing equipment stability, and the invention provides the restriction that continuous kidney replacement therapy device is not subjected to environment for use.
Description of drawings
In order to be illustrated more clearly in the embodiment of the invention and technical scheme of the prior art, the below will do to introduce simply to the accompanying drawing of required use in embodiment and the description of the Prior Art, apparently, accompanying drawing in the following describes only is some embodiments of the present invention, for those of ordinary skills, under the prerequisite of not paying creative work, can also obtain according to these accompanying drawings other accompanying drawing.
Fig. 1 is the structural representation of a kind of continuous kidney replacement therapy device provided by the invention;
Fig. 2 is the structural representation of a kind of continuous kidney replacement therapy provided by the invention system;
Fig. 3 is the control circuit figure of a kind of continuous kidney replacement therapy device provided by the invention.
The specific embodiment
The below will engage the accompanying drawing in the embodiment of the invention, and the technical scheme in the embodiment of the invention is clearly and completely described, and obviously, described embodiment only is the present invention's part embodiment, rather than whole embodiment.Based on the embodiment among the present invention, those of ordinary skills belong to the scope of protection of the invention not making the every other embodiment that obtains under the creative work prerequisite.
Please refer to shown in Figure 1ly, Fig. 1 is the structural representation of a kind of continuous kidney replacement therapy device provided by the invention.
The invention provides a kind of continuous kidney replacement therapy device, comprising: blood circuit, blood purification, blood pump, dialysis fluid circuit, dialysis liquid pump, controller and flow monitor;
Described blood circuit comprises blood sampling loop and blood back loop;
Described blood purification is connected between described blood sampling loop and the described blood back loop;
Described blood pump is arranged on the described blood sampling loop, is used for driving blood flowing on described blood sampling loop;
Described dialysis fluid circuit comprises fluid infusion loop and dehydration loop; Described fluid infusion loop is connected with described blood sampling loop; Described dehydration loop is connected with described blood purification;
Described dialysis liquid pump comprises fluid infusion pump and dehydration pump; Described fluid infusion pump is arranged on described fluid infusion loop, and described dehydration pump is arranged on the described dehydration loop;
Described flow monitor is arranged on described fluid infusion loop and the described dehydration loop; Be used for the Real-Time Monitoring fluid flow, and monitoring result is sent to described controller;
Described controller is regulated described fluid infusion pump and dehydration pump according to the result of described flow monitor monitoring or is reported to the police.
The flow monitor of the present invention by arranging at described fluid infusion loop and described dehydration loop, directly monitor liquid flow rate.For example, flow monitoring in the fluid infusion loop: when pressure variation in gateway, fluid infusion loop causes fluid flow slack-off, flow monitor sends to controller with monitoring result, the running speed of controller control fluid infusion pump, that is: improve pump speed, and then so that the fluid flow in the fluid infusion loop keeps constant.When flow monitor monitors that fluid flow is too fast in the fluid infusion loop, flow monitor sends to controller with monitoring result, the running speed of controller control fluid infusion pump, the fluid infusion pump speed is descended, and then so that liquid keeps flow inconvenience, therefore, but the liquid actual flow of flow monitor is flow through in the present invention by the flow monitor Real-Time Monitoring of installing, and according to changes in flow rate pump speed is adjusted, guarantee the constant of fluid flow with precisely.
Flow monitoring in the dehydration loop: when dehydration loop gateway pressure changes the flow cause waste liquid to be discharged when slack-off, flow monitor sends to controller with monitoring result, the running speed of controller control dehydration pump, that is: improve pump speed, and then so that the flow that waste liquid is discharged in the dehydration loop keeps constant.When flow monitor monitored that the waste liquid flow is too fast in the dehydration loop, flow monitor sent to controller with monitoring result, and the running speed of controller control dehydration pump descends dehydration pump speed, and then so that the waste liquid delivery flow keeps inconvenience.
Described flow monitor is micro flow sensor, calculates respectively the micro flow sensor of every layer of fluid flow by the mode of multiple field.Liquid flows into cavity from entrance, multilamellar cylinder structure through sensor, produce after the laminar flow effect, flow out from outlet, fluid pressure signal before and after the flow monitor Real-Time Monitoring laminar flow, and according to fluid pressure signal intensity calculating fluid flow result of variations, afterwards the result being sent to controller, controller is controlled according to this result.Therefore, the present invention has guaranteed the control of fluid flow precision greatly by directly measuring the liquid actual flow.
The invention provides a kind of continuous kidney replacement therapy device, further comprise: heater is arranged on the described fluid infusion loop; Described heater comprises and adds heat passage, and liquid enters by the liquid inlet that is arranged on described heater below, and behind the described heater of flowing through, the liquid outlet that is arranged by described heater top is transferred in the described blood back loop.
Heater of the present invention adopts thin-walled pressure vessel type heater, chamber wall volume and internal capacity ratio are less than or equal to 3:7, chamber wall is metal material or other heat-conductings, after heater heats up by chamber wall with the flow through liquid of heater of heat transferred.Heater of the present invention is strictly controlled Heat Conduction Material and internal capacity ratio, heats maximum liquid with minimum Heat Conduction Material, according to liquid flow design containers internal structure, greatly improved the efficiency of heating surface, effectively reduce complete machine power, and do not need consumptive material, greatly reduce treatment cost.Because this heater Heat Conduction Material quality is little, rapid heat dissipation, so after having solved the time-out running of liquid road, cause the problem that heats up in the liquid holdup heater.Therefore also solved the problem that heat block technology waste liquid, water route can't in time stop.
Described heater of the present invention further comprises: the discharge opeing path, liquid is discharged by the liquid outlet that described heater below arranges, and has realized effectively allotting the many functions of residual liquid.Liquid enters from described heater bottom during the heater normal operation, flows out from described heater top, and the air in the described heater is discharged from the outlet at heater top.But, when kidney replacement therapy device quits work continuously, if this continuous kidney replacement therapy device inside is left liquid for a long time, then liquid can produce salt and analyze phenomenon after evaporation, this continuous kidney replacement therapy device normal operation is impacted and corrodes, so drain the clean continuously liquid of kidney replacement therapy device inside, and then so that this continuous kidney replacement therapy device can work, and increase the service life of this continuous kidney replacement therapy device.
Described heater of the present invention further comprises: liquid level detector, be arranged on described heater top, for detection of the described liquid level that adds liquid in the heat passage, and testing result sent to described controller, prevent that liquid in the fluid infusion loop from being the dry combustion method phenomenon when being full of heater.
Described heater of the present invention further comprises: Temperature Detector, be arranged on the liquid outlet place of described heater top, and for detection of the described temperature that adds liquid in the heat passage, and testing result is sent to described controller.Controller is regulated control according to testing result to heater or is reported to the police.And then effectively realized the control of temperature of liquid in the fluid infusion loop.In addition, described Temperature Detector can be arranged on described heater top or/and the middle part or/and the bottom.
Described heater of the present invention further comprises: temperature switch, be arranged on the described heater, and described controller is controlled described temperature switch according to described temperature detection result.When described Temperature Detector detected the temperature of liquid overtemperature, controller control heater was cut off the electricity supply, and has realized the hardware protection of heater.
During for fear of the work of continuous kidney replacement therapy device, because outage and can't work the time, the present invention also comprises reserve battery, so that kidney replacement therapy device externally can keep the continuous firing of this device in the situation of dump continuously.
The cabinet of continuous kidney replacement therapy device provided by the invention adopts high-strength engineering plastic, and at the machine box surface connection buttress brace is set according to engineering mechanics, guarantees that casing effectively alleviates machine weight in the time of firm.Described buttress brace can be a L-type beam, two cabinet plane splicings place two faces is fixed.
Continuous kidney replacement therapy device provided by the invention; control circuit in controller applies protective coating; circuit surface forms layer protecting film; the problem such as effectively prevent circuit board corrosion, soften, be out of shape, go mouldy can realize that this continuous kidney replacement therapy device works for a long time at environment such as chemistry, high dirt, salt fog, moist and high temperature.The reliability of the continuous kidney replacement therapy of Effective Raise device increases its safety coefficient, and guarantees its service life, and efficiently solving hsempdiakysing systems can not be in chemistry, high dirt, smog, the long-term problem of using continuously of wet environment.
Please refer to shown in Figure 2ly, Fig. 2 is the structural representation of a kind of continuous kidney replacement therapy provided by the invention system.
Continuous kidney replacement therapy provided by the invention system comprises: blood circuit unit, blood purification unit, blood pump unit, dialysis fluid circuit unit, dialysis liquid pump unit, control unit and flow monitoring unit;
Described blood circuit unit comprises blood sampling circuit units and blood back circuit units;
Described blood purification unit is connected between described blood sampling circuit units and the described blood back circuit units;
Described blood pump unit is arranged on the described blood sampling circuit units, is used for driving blood flowing on described blood sampling circuit units;
Described dialysis fluid circuit unit comprises fluid infusion circuit units and dehydration loop unit; Described fluid infusion circuit units is connected with described blood sampling circuit units; Described blood purification unit, described dehydration loop unit connects;
Described dialysis liquid pump unit comprises fluid infusion pump unit and dehydration pump unit; Described fluid infusion pump unit is arranged on the described fluid infusion circuit units, and described dehydration pump unit is arranged on the described dehydration loop unit;
Described flow monitoring unit is separately positioned on described fluid infusion circuit units and the described dehydration loop unit; Be used for the Real-Time Monitoring fluid flow, and monitoring result is sent to described control unit;
Described control unit is regulated described fluid infusion pump unit and dehydration pump unit according to the result of the described flow monitor monitoring of receiving or is reported to the police.
Please refer to shown in Figure 3ly, Fig. 3 is the control circuit figure of a kind of continuous kidney replacement therapy device provided by the invention.
Controller of the present invention comprises power panel, panel, baffle.
Described panel is responsible for receiving fluid flow rate signal or temperature of liquid signal; and regulate control action according to signal; possesses simultaneously the logic control function; can carry out the automatically control of this device according to user's operation and signal feedback situation; when possessing the control function, panel can be realized this device logic interlock protection function, when warning message produces; panel sends guarded command, and corresponding component is quit work.Described panel is according to the fluid flow monitor signal that receives, and the regulation and control fluid flow is namely adjusted the pump speed of fluid infusion pump or dehydration pump, keeps the constant of flow velocity; Described panel can also be regulated and control heating power, and the liquid outlet temperature signal that the temperature by gathering described heater or described heater top arrange is regulated the power of heater, so that the temperature of liquid in the fluid infusion loop keeps constant temperature; Controller can also be by receiving the monitoring information such as leakage blood, pressure, concentration, bubble, liquid level, realize corresponding adjusting; Communication data between all right processing controls plate of panel and the display screen.
Described power panel is responsible for this device portal power supply is converted to the electric pressures such as 5VDC, 12VDC, 24VDC for system, possesses simultaneously control function of power.
Described baffle is the hardware protection mechanism that is independent of panel; baffle directly gathers the signal of interest of this device; when the equipment abnormal; baffle directly cuts off the action of relevant device; even panel continues output signal; this device is worked on, so baffle is the important hardware protection mechanism of this device.
The bottom of this device arranges four bases with female thread, can be used with fixture and the supporting go-cart of this matched with devices.What fix this device is two strip metallic plates, is fixed in the bottom of device both sides, and the stripe board centrage has a penetrating groove, the crotch that each cover has 2 screw rods to make, after crotch hooked the desk edge, tighten the screw rod upper nut, desk and fixture tightly are fixed together.Supporting go-cart has four perforates on the table, and four bases in big or small position and bottom of device are consistent, during use device is put on the table, and will be installed with desktop with screw and be fixed together.
The operation principle of this device is:
Blood circuit is made of flexible conduit, comprise from the patient extract blood to the blood sampling loop of blood purification, blood purification is to patient's blood back loop.The blood sampling loop is provided with a blood pump, by driving realization blood the flowing in blood circuit of blood pump.After, the blood purification of flowing through flows into the blood back loop by blood purification to blood again by gathering in the patient body, returns human body.Blood sampling loop and blood back loop respectively arrange a blood kettle fixture, after plasma viscosity kettle insertion fixture, can carry out monitoring, alarming to blood kettle liquid level.The blood back loop also arranges bubble detector and bubble binding clasp, and after bubble detector detected bubble, the bubble binding clasp clamped the blood back loop, prevents that bubble from entering human body.
Dialysis fluid circuit is made of flexible conduit, comprises fluid infusion loop and dehydration loop.Flow monitor and dialysis liquid pump (fluid infusion pump and dehydration pump) are set on fluid infusion loop and the dehydration loop, the flow of liquid in flow monitor difference this fluid infusion loop of Real-Time Monitoring and the dehydration loop, and the dialysis solution pump power revised and regulate, reach the effect of accurate coutroi velocity, by the accurate control of two cover flow monitors, realize fluid balance precision and the control of dehydration precision.The fluid infusion loop includes the equipment such as liquid implication bubble checkout gear, liquid inlet pressure-detecting device, the detection of fluid infusion pump discharge pressure, flow monitor, liquid heating, drain valve of heater door, liquid replenishing function valve, sterilizing function valve, concentration detection apparatus, temperature of liquid checkout gear.Dehydration loop comprises the equipment such as ultrafiltration pressure pressure checkout gear, dehydration pump outlet pressure checkout gear, flow monitor, leakage blood examination survey device.This device possesses arterial pressure pressure-detecting device, venous pressure pressure-detecting device and ambient pressure checkout gear simultaneously.
Need to prove, in this article, term " comprises ", " comprising " or its any other variant are intended to contain comprising of nonexcludability, thereby not only comprise those key elements so that comprise process, method, article or the equipment of a series of key elements, but also comprise other key elements of clearly not listing, or also be included as the intrinsic key element of this process, method, article or equipment.
The above only is the preferred implementation of a kind of continuous kidney replacement therapy device provided by the invention, does not consist of the restriction to protection domain of the present invention.Number of components among this embodiment is not limited to the mode that adopts among the embodiment, any any modification of doing within the spirit and principles in the present invention, is equal to and replaces and improvement etc., all should be included within the claim protection domain of the present invention.
Claims (10)
1. a continuous kidney replacement therapy device is characterized in that, comprising: blood circuit, blood purification, blood pump, dialysis fluid circuit, dialysis liquid pump, controller and flow monitor;
Described blood circuit comprises blood sampling loop and blood back loop;
Described blood purification is connected between described blood sampling loop and the described blood back loop;
Described blood pump is arranged on the described blood sampling loop, is used for driving blood flowing on described blood sampling loop;
Described dialysis fluid circuit comprises fluid infusion loop and dehydration loop; Described fluid infusion loop is connected with described blood sampling loop or blood back loop; Described dehydration loop is connected with described blood purification;
Described dialysis liquid pump comprises fluid infusion pump and dehydration pump; Described fluid infusion pump is arranged on described fluid infusion loop, and described dehydration pump is arranged on the described dehydration loop;
Described flow monitor is arranged on described fluid infusion loop and the described dehydration loop; Be used for the Real-Time Monitoring fluid flow, and monitoring result is sent to described controller;
Described controller is regulated described fluid infusion pump and dehydration pump according to the result of described flow monitor monitoring or is reported to the police.
2. continuous kidney replacement therapy device according to claim 1 is characterized in that described flow monitor is micro flow sensor.
3. continuous kidney replacement therapy device according to claim 1 is characterized in that, further comprises: heater, be arranged on the described fluid infusion loop, and adopt thin-walled pressure vessel type structure; Described heater comprises and adds heat passage, and liquid enters by the liquid inlet that is arranged on described heater below, and behind the described heater of flowing through, the liquid outlet that is arranged by described heater top is transferred in the described blood back loop.
4. continuous kidney replacement therapy device according to claim 3 is characterized in that described heater further comprises: discharge opeing path, the liquid outlet discharge that liquid arranges by described heater below.
5. continuous kidney replacement therapy device according to claim 3, it is characterized in that described heater further comprises: liquid level detector is arranged on described heater top, for detection of the described liquid level that adds liquid in the heat passage, and testing result sent to described controller.
6. continuous kidney replacement therapy device according to claim 3, it is characterized in that, described heater further comprises: Temperature Detector, be arranged on the liquid outlet place of described heater top, for detection of the described temperature that adds liquid in the heat passage, and testing result is sent to described controller.
7. continuous kidney replacement therapy device according to claim 6 is characterized in that described heater further comprises: temperature switch, be arranged on the described heater, and described controller is controlled described temperature switch according to described temperature detection result.
8. continuous kidney replacement therapy device according to claim 1 is characterized in that, further comprise: reserve battery is positioned on the described controller.
9. continuous kidney replacement therapy device according to claim 1 is characterized in that the cabinet of described therapy equipment is the highstrenghtpiston.
10. a continuous kidney replacement therapy system is characterized in that, comprising: blood circuit unit, blood purification unit, blood pump unit, dialysis fluid circuit unit, dialysis liquid pump unit, control unit and flow monitoring unit;
Described blood circuit unit comprises blood sampling loop subelement and blood back loop subelement;
Described blood purification unit is connected between described blood sampling loop subelement and the described blood back loop subelement;
Described blood pump unit is arranged on the described blood sampling circuit units, is used for driving blood flowing in the subelement of described blood sampling loop;
Described dialysis fluid circuit unit comprises fluid infusion loop subelement and dehydration loop subelement; Described fluid infusion loop subelement is connected with described blood sampling loop subelement; The described blood purification of described dehydration loop subelement unit connects;
Described dialysis liquid pump unit comprises fluid infusion pump subelement and dehydration pump subelement; Described fluid infusion pump subelement is arranged on the subelement of described fluid infusion loop, and described dehydration pump subelement is arranged on the described dehydration loop subelement;
Described flow monitoring unit is separately positioned on described fluid infusion loop subelement and the described dehydration loop subelement; Be used for the Real-Time Monitoring fluid flow, and monitoring result is sent to described control unit;
Described control unit is regulated described fluid infusion pump subelement and dehydration pump subelement according to the result of the described flow monitor monitoring of receiving or is reported to the police.
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| CN2012104222435A CN102895711A (en) | 2012-10-29 | 2012-10-29 | Device for continuous renal replacement therapy (CRRT) |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102961790A (en) * | 2012-11-14 | 2013-03-13 | 王雪 | Continuous renal replacement therapy device |
| CN104623750A (en) * | 2013-11-13 | 2015-05-20 | 甘布罗伦迪亚股份公司 | Dialysis monitors, use of battery units of dialysis monitors,and methods relating to heating of fluids |
| CN104689397A (en) * | 2015-03-05 | 2015-06-10 | 昆山韦睿医疗科技有限公司 | Peritoneal dialysis system |
| CN104971391A (en) * | 2015-06-19 | 2015-10-14 | 南方医科大学珠江医院 | Novel combined type liver and kidney support system CRRT mode tube |
| CN105498004A (en) * | 2016-01-14 | 2016-04-20 | 青岛大学附属医院 | Continuous renal replacement therapy device |
| CN109689126A (en) * | 2016-09-12 | 2019-04-26 | 日机装株式会社 | Apparatus for purifying blood |
| US11419969B2 (en) | 2019-03-26 | 2022-08-23 | Nuwellis, Inc. | Neonatal and pediatric blood filtration system |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102961790A (en) * | 2012-11-14 | 2013-03-13 | 王雪 | Continuous renal replacement therapy device |
| CN104623750A (en) * | 2013-11-13 | 2015-05-20 | 甘布罗伦迪亚股份公司 | Dialysis monitors, use of battery units of dialysis monitors,and methods relating to heating of fluids |
| US10610628B2 (en) | 2013-11-13 | 2020-04-07 | Gambro Lundia Ab | Dialysis monitors, methods relating to heating of fluids, and use of battery units of dialysis monitors |
| CN104689397A (en) * | 2015-03-05 | 2015-06-10 | 昆山韦睿医疗科技有限公司 | Peritoneal dialysis system |
| CN104971391A (en) * | 2015-06-19 | 2015-10-14 | 南方医科大学珠江医院 | Novel combined type liver and kidney support system CRRT mode tube |
| WO2016201783A1 (en) * | 2015-06-19 | 2016-12-22 | 南方医科大学珠江医院 | Novel assembly-type crrt-mode tubing system for liver and kidney support system |
| CN105498004A (en) * | 2016-01-14 | 2016-04-20 | 青岛大学附属医院 | Continuous renal replacement therapy device |
| CN109689126A (en) * | 2016-09-12 | 2019-04-26 | 日机装株式会社 | Apparatus for purifying blood |
| US11419969B2 (en) | 2019-03-26 | 2022-08-23 | Nuwellis, Inc. | Neonatal and pediatric blood filtration system |
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