CN205287055U - Blood purification device - Google Patents
Blood purification device Download PDFInfo
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- CN205287055U CN205287055U CN201521035244.XU CN201521035244U CN205287055U CN 205287055 U CN205287055 U CN 205287055U CN 201521035244 U CN201521035244 U CN 201521035244U CN 205287055 U CN205287055 U CN 205287055U
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Abstract
The utility model discloses a BLOOD PURIFICATION DEVICE, BLOOD PURIFICATION DEVICE is including blood sampling route, time blood route, dislysate / replacement liquid route, waste liquid route, filter and controller, the blood sampling route, return blood route, dislysate route / replacement liquid route and the equal detachable of waste liquid route and the filter is connected, be equipped with first pipeline and first peristaltic pump mechanism on the blood sampling route, first peristaltic pump mechanism is used for doing first pipeline provides drive power. The utility model provides a BLOOD PURIFICATION DEVICE compact structure, and can realize on a machine that hemodialysis, blood are filtered, hemoperfusion and ultrafiltration mode, the utility model discloses well BLOOD PURIFICATION DEVICE comes the flow in real -time supervision blood return circuit, dislysate route, replacement liquid route and the waste liquid route through flow sensor, and this kind of monitoring mode be non -contact, and the sensor need not contact the dislysate, and precision height does not moreover receive the influence of adverse circumstances such as vibration, is applicable to portable instrument.
Description
Technical field
This utility model belongs to medical instruments field, is specifically related to a kind of apparatus for purifying blood.
Background technology
CRRT (continuousrenalreplacementtherapy, continuous renal replacementtherapy) has another name called bedside hemo-filtration. Definition is to adopt 24 hours every days or long-time close to the one of 24 hours, and continuous print extracorporeal blood purifies therapy to substitute impaired renal function. Blood purification is blood samples of patients to be caused external and passes through a kind of purifier, removes some of which morbid substance purification blood and reaches the purpose for the treatment of disease. It mainly includes hemodialysis, hemofiltration, hemodiafiltration, hemoperfusion, plasmapheresis, immunoadsorption, peritoneal dialysis etc. Current blood purification therapy has not been provided purely for treating acute and chronic patients with renal failure, have also been obtained and be widely applied in the rescue of Severe acute disease patient.
CRRT clinical practice target is excess moisture in purged body, purged body intracellular metabolite refuse, poisonous substance, corrects Electrolyte imbalance, it is ensured that nutritional support, promotes graft function and removes various cytokine, inflammatory mediator. Can be used for: various cardiovascular functioies instability, Metabolism or companion's cerebral edema acute and chronic renal failure, and multiple organs dysfunction syndrome, acute respiratory distress syndrome, crush syndrome, acute necrotizing pancreatitis, chronic heart failure, hepatic encephalopathy, the treatment of medicine and toxic poisoning etc.
But, currently known CRRT machine yet suffers from defect: its volume still comparatively both bulk, not easily carries, more can not meet with the portable needs carried of military operation. In the blood purification treatment of military operation or a line War injury treatment of " non-war " uses of force, wild environment is harsh, power supply, water source, the weight of equipment and the operation of equipment are required high, in prior art, CRRT is not easily portable carries, and it is easily damaged or causes instrument unstable under the environment jolting, wave and vibrating, can not work completely, it is impossible to implement emergency aid and treatment.It is not suitable for the small portable continuous blood purification device of line treatment in wartime one and field rescue, disaster relief at present.
Utility model content
The shortcoming of prior art in view of the above, the purpose of this utility model is in that to provide a kind of apparatus for purifying blood, to overcome apparatus for purifying blood in prior art bulky, to the defect using environmental requirement height and unitary device function singleness.
In order to reach above-mentioned utility model purpose and other purposes, this utility model is achieved through the following technical solutions:
This utility model provides a kind of apparatus for purifying blood, and described apparatus for purifying blood includes blood sampling tube, blood back path, dialysis solution/displacement liquid path, waste liquid path, filter and controller;
Described blood sampling tube, blood back path, dialysis solution path/displacement liquid path and waste liquid path be all dismountable and described filter is connected; Described blood sampling tube is provided with the first pipeline and for providing the first peristaltic pump mechanism of driving force for described first pipeline;
Described dialysis solution/displacement liquid path is provided with the 3rd pipeline, for providing the second peristaltic pump mechanism of driving force and for monitoring the flow of liquid in described 3rd pipeline in real time for described 3rd pipeline, and monitoring result is sent to the first flow sensor of described controller;
Described waste liquid path is provided with the 4th pipeline, for providing the 3rd peristaltic pump mechanism of driving force for described 4th pipeline and for monitoring the flow of liquid in the 4th pipeline in real time and sending monitoring result to the second flow sensor of described controller.
The operating of described 3rd peristaltic pump mechanism and described 4th peristaltic pump mechanism is adjusted or reports to the police according to the monitoring result of described first flow sensor and second flow sensor by described controller.
Dialysis solution described in this utility model/displacement liquid path refers to dialysis solution path or displacement liquid path. In this utility model adopt symbol "/" all represent or the meaning.
Preferably, described blood sampling tube being additionally provided with anticoagulant syringe and for providing the anticoagulant syringe pump of power to described anticoagulant syringe, described anticoagulant syringe is connected with described first pipeline by pipeline.
Preferably, described blood sampling tube being additionally provided with the pressure for monitoring on described first pipeline and monitoring result is sent pressure transducer to the filter of described controller, before described filter, pressure transducer is located between the first peristaltic pump mechanism and described filter. Described controller carries out the judgement of calculation of pressure and pressure alarm according to the result of pressure sensor monitoring before described filter.
Preferably, described blood sampling tube being additionally provided with arterial pressure sensor, the flow direction of liquid in the first pipeline on described blood sampling tube, described arterial pressure sensor is located at the upstream of described first peristaltic pump mechanism.
Preferably, described blood back path includes the second pipeline, and the liquid flow direction along described second pipeline is provided with bubble detector and venous check valve.
Preferably, described blood back path is additionally provided with the pressure for monitoring on described second pipeline and monitoring result is sent the venous pressure sensor to described controller, the flow direction of liquid in the second pipeline, described venous pressure sensor is positioned at the upstream of described bubble detector. Described controller carries out the judgement of calculation of pressure and pressure alarm according to the result that described venous pressure sensor is monitored.
Preferably, the entrance that described dialysis solution/displacement liquid path is additionally provided with memory unit, described memory unit and described 3rd pipeline removably connects.
Preferably, the 3rd pipeline is additionally provided with the first degasification kettle, described first degasification kettle and described 3rd pipeline connection, and along the liquid flow direction in described 3rd pipeline, described first degasification kettle is positioned at the upstream of described first flow sensor.
Preferably, described waste liquid path is provided with the pressure for monitoring on described 4th pipeline and monitoring result is sent the waste liquid pressure transducer to described controller, the flow direction of liquid in described 4th pipeline, described waste liquid pressure transducer is located at the upstream of described 3rd peristaltic pump mechanism. Described controller carries out the judgement of calculation of pressure and pressure alarm according to the result that described waste liquid pressure transducer detects.
Preferably, described waste liquid path being additionally provided with Lou blood sensor, the flow direction of liquid on described 4th pipeline, the upstream of described 3rd peristaltic pump mechanism is located at by described leakage blood sensor.
Preferably, described waste liquid path is additionally provided with the second degasification kettle, described second degasification kettle and described 4th pipeline connection, and along the liquid flow direction in described 4th pipeline, described second degasification kettle is positioned at the upstream of described second flow sensor.
Preferably, described first flow sensor and second flow sensor are ultrasonic flow sensor, and described ultrasonic flow sensor includes with lower component:
For ultrasonic flow sensor being fixed on the fixing parts on the 3rd pipeline or the 4th pipeline;
It is arranged on the side of pipeline, in order to launch hyperacoustic ultrasonic transmitter to pipeline;
The opposite side being arranged on pipeline is relative with ultrasonic transmitter, in order to receive the ultrasonic receiver of ultrasonic signal from described ultrasonic transmitter output current signal.
Preferably, described apparatus for purifying blood also includes the signal sent for receiving described first flow sensor and second flow sensor calculated flow rate, the metering device of output flow signal.
Preferably, described metering device includes with lower part:
For the current signal from flow transducer being converted to the signaling conversion circuit of voltage signal;
It is connected with signaling conversion circuit, for voltage signal being reconverted into the signal acquisition circuit of digital signal;
It is connected with signal acquisition circuit, for receiving digital signal and calculating the data processing unit of output stream value.
It is highly preferred that described data processing unit is used for receiving digital signal and calculating output stream value by formula I, II, V;
Wherein, v1: by the instantaneous equivalent value of the flow rate of liquid of first flow sensor; v2: by the instantaneous equivalent value of the flow rate of liquid of second flow sensor; T: cumulative time; V1: the accumulative total amount of liquid by first flow sensor; V2: the accumulative total amount of liquid by second flow sensor;
V=(Vot/Vmax)��vmax(V),
Wherein, v: the instantaneous equivalent value of flow rate of liquid; Vot: the instantaneous digital voltage signal of flow rate of liquid; Vmax: the digital voltage signal that liquid Peak Flow Rate is corresponding; vmax: liquid Peak Flow Rate equivalent value.
Preferably, described 3rd peristaltic pump mechanism includes the 3rd peristaltic pump and the 3rd peristaltic pump electric driver concurrently sending motor speed feedback signal for driving the 3rd peristaltic pump to rotate; Described apparatus for purifying blood also includes:
It is connected with metering device and the 3rd peristaltic pump electric driver, receive the flow signal of automatic measurer and from the motor speed feedback signal of the 3rd peristaltic pump electric driver, and send the balance control device of motor speed control signal to the 3rd peristaltic pump electric driver.
Preferably, described 3rd peristaltic pump electric driver includes with lower part:
It is connected with the 3rd peristaltic pump motor driver, for driving the rotation of the 3rd peristaltic pump, and with being used for sending the 3rd peristaltic pump motor of the negative feedback loop of motor speed feedback signal; Described 3rd peristaltic pump motor is motor;
It is connected with the 3rd peristaltic pump motor and balance control device, receiving balance controls the motor speed control signal of device transmission and controls the 3rd peristaltic pump motor speed, receives the motor speed feedback signal that the 3rd peristaltic pump motor sends the 3rd peristaltic pump motor driver being transferred to balance control device.
Preferably, described balance control device includes with lower part:
For calculating the computing unit obtaining actual ultrafiltration total amount;
For setting the setting ultrafiltration total amount unit of ultrafiltration total amount;
It is connected with the 3rd peristaltic pump electric driver, receives the signal feedback unit of the motor speed feedback signal from the 3rd peristaltic pump electric driver;
It is connected with actual ultrafiltration total amount calculating unit, setting ultrafiltration total amount unit and signal feedback unit respectively, calculates the 3rd peristaltic pump adjustment of rotational speed computing unit of the motor speed of the 3rd peristaltic pump mechanism;
It is connected with the 3rd peristaltic pump adjustment of rotational speed computing unit and the 3rd peristaltic pump electric driver, sends the signal transmitting unit of the motor speed control signal adjusting motor speed to the 3rd peristaltic pump electric driver.
Obtain it is highly preferred that described actual ultrafiltration total amount calculates according to formula III:
UF=V2-V1(III),
Wherein, UF: actual ultrafiltration total amount; V1: the accumulative total amount of liquid by first flow sensor; V2: accumulative by the
The total amount of liquid of two flow transducers.
It is highly preferred that calculate the rotating speed of the 3rd peristaltic pump motor according to formula IV:
vUseless=vUseless 0+(UFref�CUF)/(t��VStep) (IV),
Wherein, vUseless: the rotating speed of the 3rd peristaltic pump motor; vUseless 0: the current rotating speed of the 3rd peristaltic pump motor; UFref: set ultrafiltration total amount; UF: actual ultrafiltration total amount; T: cumulative time; VStep: the flow that the 3rd peristaltic pump motor is every turn corresponding. Sending to the 3rd peristaltic pump electric driver and adjusting motor speed is vUseless��
Preferably, described second peristaltic pump mechanism includes the second peristaltic pump and the described second peristaltic pump electric driver for driving described second peristaltic pump to rotate.
It is highly preferred that described second peristaltic pump electric driver includes with lower part:
For driving the second peristaltic pump motor of the rotation of the second peristaltic pump;
It is connected with the second peristaltic pump motor, for controlling the second peristaltic pump motor driver of the rotating speed of the second peristaltic pump motor.
Preferably, described first peristaltic pump mechanism includes the first peristaltic pump and the described first peristaltic pump electric driver for driving described first peristaltic pump to rotate.
It is highly preferred that described first peristaltic pump electric driver includes with lower part:
For driving the first peristaltic pump motor of the rotation of the first peristaltic pump;
It is connected with the first peristaltic pump motor, for controlling the first peristaltic pump motor driver of the rotating speed of the first peristaltic pump motor.
Preferably, described 3rd peristaltic pump motor, the second peristaltic pump motor and the first peristaltic pump motor are motor. Described motor is with negative feedback loop, it is possible to send motor speed feedback signal. It is specially the AR series motor of east motor, essentially all of servo motor model number etc. On off control is accurate, can accurately detect electric machine rotation distance (number of motor steps).
Whether negative feedback loop described in this utility model is used for feeding back motor speed, and specifically, negative feedback loop gathers the actual step value of motor, exist lose the serious exception of step for monitoring motor. Peristaltic pump motor often makes a move and will provide a feedback pulse, the feedback pulse that negative feedback loop is monitored by negative feedback control device adds up, and the pulse added up in the unit interval is converted as motor speed, set rotating speed as reference value and theory to compare, if feedback loop motor speed value exceedes theory sets rotating speed certain limit, it is determined that seriously lose step, it is considered as electrical fault, it is necessary to do corresponding operation stopping motor rotation and check.
In preferred embodiment of the present utility model, filter is in order to purify blood. Preferably, the interior intracavity of described filter is provided with filter membrane, and filter inner chamber is separated into the blood flowing space and dialysis solution/waste liquid flowing space by filter membrane; Described first pipeline accesses the blood flowing space of filter, and described second pipeline picks out from the blood flowing space of filter; 3rd pipeline is selectively accessing the dialysis solution/waste liquid flowing space of filter or the arbitrary of the blood flowing space, and described 4th pipeline picks out from the dialysis solution of filter/waste liquid flowing space.
Preferably, described apparatus for purifying blood includes cooling system, and described cooling system includes the internal temperature for monitoring described apparatus for purifying blood and testing result sends the temperature sensor to described controller and fan. Described controller regulates and controls the operating of described fan according to the result of described temperature sensor monitors.
Preferably, described apparatus for purifying blood includes housing. Described housing adopts PC/ABS composite.
Preferably, described apparatus for purifying blood also includes the display of the information of all parameters for showing in described controller, warning, prompting and setting.
Apparatus for purifying blood in this utility model has the advantages that
1) the apparatus for purifying blood compact conformation in this utility model, and hemodialysis, hemofiltration, hemoperfusion and ultrafiltration pattern can be realized on a machine;
2) in this utility model, apparatus for purifying blood monitors the flow in blood sampling tube, dialysis solution/displacement liquid path and waste liquid path in real time by flow transducer, this monitoring mode is contactless, sensor need not contact dialysis solution, and precision is high, the impact of the adverse circumstances such as not vibrated, it is adaptable to portable set;
3) in this utility model, apparatus for purifying blood cooperates to realize the balance of each path liquid in apparatus for purifying blood with the first peristaltic pump mechanism on blood sampling tube, the second peristaltic pump mechanism on dialysis solution/displacement liquid path and the 3rd peristaltic pump mechanism on waste liquid path by flow transducer; Peristaltic pump itself has degeneration factor can carry out feedback regulation, the flow of the real-time monitoring of blood of flow transducer, dialysis solution/displacement liquid and waste liquid, and the speed of feedback regulation peristaltic pump to compensate error, to improve precision; Patient's cross infection avoided by this contactless flow transducer, and peristaltic pump self negative feedback is calibrated, it is possible to increase precision.
Apparatus for purifying blood disclosed in this utility model overcomes many disadvantages of the prior art and creative.
Accompanying drawing explanation
Fig. 1 is the hemodialysis model process figure of apparatus for purifying blood described in this utility model.
Fig. 2 is the hemofiltration model process figure of apparatus for purifying blood described in this utility model.
Fig. 3 is the ultrafiltration model process figure of apparatus for purifying blood described in this utility model.
Fig. 4 is the hemoperfusion model process figure of apparatus for purifying blood described in this utility model.
Accompanying drawing labelling in Fig. 1��4 is as follows:
11 is the first pipeline;
12 is the first peristaltic pump mechanism;
13 is anticoagulant syringe pump;
14 is anticoagulant syringe;
15 is pressure transducer before filter;
16 is arterial pressure sensor;
21 is the second pipeline;
22 is bubble detector;
23 is venous check valve;
24 is venous pressure sensor;
31 is the 3rd pipeline;
32 is the second peristaltic pump mechanism;
33 is first flow sensor
34 is memory unit;
41 is the 4th pipeline;
42 is the 3rd peristaltic pump mechanism;
43 is leakage blood sensor;
44 is waste liquid pressure transducer;
45 is second flow sensor;
5 is filter.
Detailed description of the invention
Below by way of specific instantiation, embodiment of the present utility model being described, those skilled in the art the content disclosed by this specification can understand other advantages of the present utility model and effect easily. This utility model can also be carried out by additionally different detailed description of the invention or apply, and the every details in this specification based on different viewpoints and application, can also carry out various modification or change under without departing from spirit of the present utility model.
The open a kind of apparatus for purifying blood of the present embodiment, described apparatus for purifying blood includes blood sampling tube, blood back path, dialysis solution/displacement liquid path, waste liquid path and filter 5;
Described blood sampling tube, blood back path, dialysis solution path/displacement liquid path and waste liquid path be all dismountable and described filter 5 is connected;
Described blood sampling tube is provided with the first pipeline 11 and for providing the first peristaltic pump mechanism 12 of driving force for described first pipeline 11;
Described dialysis solution/displacement liquid path is provided with the 3rd pipeline 31, for providing the second peristaltic pump mechanism 32 of driving force for described 3rd pipeline 31 and for monitoring the flow of liquid in described 3rd pipeline 31 in real time and sending monitoring result to the first flow sensor 33 of described controller;
Described waste liquid path is provided with the 4th pipeline 41, for providing the 3rd peristaltic pump mechanism 42 of driving force for described 4th pipeline 41 and for monitoring the flow of liquid in the 4th pipeline 41 in real time, and monitoring result is sent the second flow sensor 45 to described controller;
Described apparatus for purifying blood also includes the controller that the operating of described second peristaltic pump mechanism 32 and described 3rd peristaltic pump mechanism 42 is adjusted or reports to the police by the monitoring result according to described first flow sensor 33 and second flow sensor 45.
Apparatus for purifying blood of the prior art generally all adopts 4 peristaltic pumps, and this utility model just can realize hemodialysis, hemofiltration, hemoperfusion and four kinds of patterns of blood ultrafiltration only with 3 peristaltic pumps simultaneously, this is greatly saved the space of apparatus for purifying blood.
In one embodiment, described blood sampling tube being additionally provided with anticoagulant syringe 14 and for providing the anticoagulant syringe pump 13 of power to described anticoagulant syringe 14, described anticoagulant syringe 14 is connected with described first pipeline 11 by pipeline.
In a preferred embodiment, described anticoagulant syringe pump 13 is made up of control circuit, motor, the fixing seat of syringe, directed screw mandrel, grating feedback and microswitch. Its operation principle is: described motor drives directed screw mandrel so that the slide block on directed screw mandrel drives anticoagulant syringe 14 to push ahead, it is achieved the injection of anticoagulant.More specifically, the precision of motor is high, and adopt optical grating constitution negative feedback loop, adjust motor pulse width, accurately control anticoagulant injection speed and injection rate; Microswitch for position detection is when syringe injection is complete, triggers switching signal, and system provides corresponding prompting, syringe monitoring microswitch, can be determined that whether syringe is in place, controlling to control anticoagulant injection rate by control system, filling soon thus realizing anticoagulant.
In one embodiment, described blood sampling tube is additionally provided with for monitoring the pressure on described first pipeline 11, and monitoring result is sent pressure transducer 15 to the filter of described controller, before described filter, pressure transducer 15 is located between the first peristaltic pump mechanism 12 and described filter 5. Described controller carries out the judgement of calculation of pressure and pressure alarm according to the result of pressure transducer 15 monitoring detection before described filter. Before filter, pressure transducer 15 is to measure the pressure when blood enters filter.
In one embodiment, described blood sampling tube being additionally provided with arterial pressure sensor 16, the flow direction of liquid in the first pipeline 11 on described blood sampling tube, described arterial pressure sensor 16 is located at the upstream of described first peristaltic pump mechanism 12. Described arterial pressure sensor is to measure the external pressure when blood leaves patient blood path, and the measurement of its arterial pressure is the suction in order to prevent the first peristaltic pump mechanism Overexertion.
In one embodiment, described blood back path 2 includes the second pipeline 21, and the liquid flow direction along described second pipeline 21 is provided with bubble detector 22 and venous check valve 23.
In one embodiment, described blood back path is additionally provided with for monitoring the pressure on described second pipeline 21, and monitoring result is sent the venous pressure sensor 24 to described controller, the flow direction of liquid in the second pipeline 21, described venous pressure sensor 24 is positioned at the upstream of described bubble detector 21. Described controller carries out the judgement of calculation of pressure and pressure alarm according to the result that described venous pressure sensor 24 is monitored. Described venous pressure sensor be measure when blood from external feed back to patient blood path time pressure, the measurement of venous pressure is to run into excessive resistance when preventing blood recovery.
In a preferred embodiment, described bubble detector 22 includes ultrasonic transmitter, receptor and observation circuit; Utilize in the principle detection blood back path of the ultrasonic rapid decay of Propagation of Energy in atmosphere with or without being mixed into bubble; It can monitor the bubble more than 50 microlitres, it is prevented that bubble enters human body, causes life danger; And form a set of linked system with venous clamp, when bubble being detected, stop blood pump operating, venous clamp pinch off venous line, it is prevented that bubble enters human body. Then pass through the bubble sucking-off that syringe will contain blood back path from venous sampling ports, to remove bubble.
In one embodiment, described dialysis solution/displacement liquid path being additionally provided with memory unit 34, the entrance of described memory unit 34 and described 3rd pipeline 31 removably connects. Memory unit 34 is conveniently replaceable. In order to reduce the weight of apparatus for purifying blood further, increasing its portability, described memory unit 34 can adopt dialyzate bag.
In one embodiment, 3rd pipeline 31 is additionally provided with the first degasification kettle, described first degasification kettle connects with described 3rd pipeline 31, and along the liquid flow direction in described 3rd pipeline 31, described first degasification kettle is positioned at the upstream of described first flow sensor 33.
In one embodiment, described waste liquid path is provided with for monitoring the pressure on described 4th pipeline 41, and monitoring result is sent the waste liquid pressure transducer 44 to described controller, the flow direction of liquid in described 4th pipeline 41, described waste liquid pressure transducer 44 is located at the upstream of described 3rd peristaltic pump mechanism 42. Described controller carries out the judgement of calculation of pressure and pressure alarm according to the result that described waste liquid pressure transducer 44 detects. Waste liquid pressure transducer 44 is the pressure in measurement waste-solution line when filter liquor leaves filter 5, and according to selected therapeutic scheme and ultrafiltration rate, waste liquid pressure can be malleation or negative pressure.
In one embodiment, described waste liquid path being additionally provided with Lou blood sensor 43, the flow direction of liquid on described 4th pipeline 41, the upstream of described 3rd peristaltic pump mechanism 42 is located at by described leakage blood sensor 43.
In a preferred embodiment, described leakage blood sensor 43 is made up of light emitting diode and colour recognition chip; White light-emitting diode is luminous, arrives colour recognition chip through pipeline, chip output RGB frequency values, is converted to HSL value (colourity, saturation and lightness) by algorithm, determines whether leakage blood by these three index and threshold value; It has highly sensitive, more accurately and by ambient disturbs smaller advantage.
In one embodiment, described waste liquid path is additionally provided with the second degasification kettle, described second degasification kettle connects with described 4th pipeline 41, and along the liquid flow direction in described 4th pipeline 41, described second degasification kettle is positioned at the upstream of described second flow sensor 45.
In a preferred embodiment, described blood sampling tube and also be provided with degasification kettle on described blood back path.
In this utility model preferred embodiment, described first pipeline is provided with the 3rd degasification kettle, described 3rd degasification kettle and described first pipeline connection.
In this utility model preferred embodiment, described second pipeline is provided with the 4th degasification kettle, described 4th degasification kettle and described second pipeline connection.
In this utility model preferred embodiment, described degasification kettle degasification, is get rid of the bubble in liquid.
In a preferred embodiment, described apparatus for purifying blood includes the outlet of waste liquid memory unit, described waste liquid memory unit and described waste liquid path and removably connects. In order to reduce the weight of apparatus for purifying blood further, increasing its portability and convertibility, described waste liquid memory unit can adopt waste fluid bag.
In a preferred embodiment, described first flow sensor 33 and second flow sensor 45 are ultrasonic flow sensor, and described ultrasonic flow sensor includes with lower component:
For ultrasonic flow sensor being fixed on the fixing parts on the 3rd pipeline 31 or the 4th pipeline 41;
It is arranged on the side of pipeline 31/41, in order to launch hyperacoustic ultrasonic transmitter to pipeline 31/41;
The opposite side being arranged on pipeline 31/41 is relative with ultrasonic transmitter, in order to receive from described ultrasonic transmitter and to be transferred to the ultrasonic signal of ultrasonic receiver the ultrasonic receiver of output current signal.
This utility model adopts ultrasonic flow sensor detection flow, decreases machine volume on the one hand, on the other hand, also can be precisely controlled fluid balance in the environment that jolts.
Described ultrasonic flow sensor has the advantage that (1) is without any mechanical transmission component, do not contact fluid to be measured, belong to non-contact measurement, be not afraid of electromagnetic interference yet, not being afraid of the strongly corrosion liquids etc. such as soda acid, therefore stable performance, reliability is high, the life-span is long;(2) its response time is short can realize easily without delayed real-time measurement. (3) not by the impact of tested temperature of liquid and viscosity; (4) moving or vibrations process still can accurately measure.
In a preferred embodiment, described metering device includes with lower part:
For the current signal from flow transducer being converted to the signaling conversion circuit of voltage signal;
It is connected with signaling conversion circuit, for voltage signal being reconverted into the signal acquisition circuit of digital signal;
It is connected with signal acquisition circuit, for receiving digital signal and calculating the data processing unit of output stream value.
It is connected with signal acquisition circuit, is used for receiving digital signal and calculates output stream value by formula I, II, V;
Wherein, v1: by the instantaneous equivalent value of the flow rate of liquid of first flow sensor; v2: by the instantaneous equivalent value of the flow rate of liquid of second flow sensor; T: cumulative time; V1: the accumulative total amount of liquid by first flow sensor; V2: the accumulative total amount of liquid by second flow sensor;
V=(Vot/Vmax)��vmax(V),
Wherein, v: the instantaneous equivalent value of flow rate of liquid; Vot: the instantaneous digital voltage signal of flow rate of liquid; Vmax: the digital voltage signal that liquid Peak Flow Rate is corresponding; vmax: liquid Peak Flow Rate equivalent value.
In preferred embodiment of the present utility model, signaling conversion circuit includes the sampling resistor of series connection and electric current turns voltage module, and electric current turns voltage module and the current signal received is converted to voltage signal.
In the preferred embodiment of this utility model, the voltage signal values that signaling conversion circuit is changed is 0��5V.
In a preferred embodiment, described 3rd peristaltic pump mechanism includes the 3rd peristaltic pump and for driving the rotation of the 3rd peristaltic pump concurrently to send the 3rd peristaltic pump electric driver of motor speed feedback signal; Described apparatus for purifying blood includes:
It is connected with metering device and the 3rd peristaltic pump electric driver, receive the flow signal of automatic measurer and from the motor speed feedback signal of the 3rd peristaltic pump electric driver, and send the balance control device of motor speed control signal to the 3rd peristaltic pump electric driver.
In one more preferably embodiment, described 3rd peristaltic pump electric driver includes with lower part:
It is connected with the 3rd peristaltic pump motor driver, for driving the rotation of the 3rd peristaltic pump, and with negative feedback loop, sends the 3rd peristaltic pump motor of motor speed feedback signal; 3rd peristaltic pump motor is motor;
It is connected with the 3rd peristaltic pump motor and balance control device, receiving balance controls the motor speed control signal of device transmission and controls the 3rd peristaltic pump motor speed, receives the motor speed feedback signal that the 3rd peristaltic pump motor sends the 3rd peristaltic pump motor driver being transferred to balance control device.
In a preferred embodiment, described balance control device includes with lower part:
For calculating the actual ultrafiltration total amount calculating unit obtaining actual ultrafiltration total amount;
For setting the setting ultrafiltration total amount unit of ultrafiltration total amount;
It is connected with the 3rd peristaltic pump electric driver, receives the signal feedback unit of the motor speed feedback signal from the 3rd peristaltic pump electric driver;
It is connected with actual ultrafiltration total amount calculating unit, setting ultrafiltration total amount unit and signal feedback unit respectively, calculates the 3rd peristaltic pump adjustment of rotational speed computing unit of the motor speed of the 3rd peristaltic pump;
It is connected with the 3rd peristaltic pump adjustment of rotational speed computing unit and the 3rd peristaltic pump electric driver, sends the signal transmitting unit of the motor speed control signal adjusting motor speed to the 3rd peristaltic pump electric driver.
More specifically, the actual ultrafiltration total amount of acquisition is calculated according to formula III:
UF=V2-V1(III),
Wherein, UF: actual ultrafiltration total amount; V1: the accumulative total amount of liquid by first flow sensor; V2: accumulative by the
The total amount of liquid of two flow transducers.
More specifically, the rotating speed of the 3rd peristaltic pump motor is calculated according to formula IV:
vUseless=vUseless 0+(UFref�CUF)/(t��VStep) (IV),
Wherein, vUseless: the rotating speed of the 3rd peristaltic pump motor; vUseless 0: the current rotating speed of the 3rd peristaltic pump motor; UFref: set ultrafiltration total amount; UF: actual ultrafiltration total amount; T: cumulative time; VStep: the flow that the 3rd peristaltic pump is every turn corresponding. Adjustment motor speed is vUseless��
Ultrasonic signal is sent by the first flow sensor and second flow sensor being all ultrasonic flow sensor, ultrasonic flow sensor is by ultrasonic emitting to pipeline, and is converted to current signal output by the flow rate of liquid signal that ultrasonic receiver received ultrasonic signal is corresponding. Received current signal by signaling conversion circuit in metering device and be converted to voltage signal, and be converted to after digital signal through signal acquisition circuit, data processing unit receive digital signal output stream value. Being received output stream value by electric machine controller in electric driver concurrently to send and control signal to motor, motor regulates revolution speed according to control signal, so that actual liquid flow velocity reaches the requirement of setting value, and the rate signal of feedback pump is to electric machine controller.
Apparatus for purifying blood disclosed in employing this utility model is above-mentioned controls the method for fluid balance and specifically includes the following step:
Step S101, arranges first flow sensor in dialysis solution/displacement liquid path, utilizes first flow sensor to obtain in the cumulative time by the total amount of liquid V of first flow sensor according to formula I1; Waste liquid path arranges second flow sensor, utilizes second flow sensor to obtain in the cumulative time by the total amount of liquid V of second flow sensor according to formula II2; Described formula I is:Described formula II is:Wherein, v1: by the instantaneous equivalent value of the flow rate of liquid of first flow sensor; v2: by the instantaneous equivalent value of the flow rate of liquid of second flow sensor; T: cumulative time; V1: the accumulative total amount of liquid by first flow sensor; V2: the accumulative total amount of liquid by second flow sensor;
Step S102, obtains actual ultrafiltration total amount UF according to formula III, and described formula III is: UF=V2-V1;
Step S103, it is thus achieved that set ultrafiltration total amount UFref;
Step S104, it is thus achieved that the 3rd peristaltic pump current motor rotating speed vUseless 0;
Step S105, calculates the motor speed v of the 3rd peristaltic pump by formula IVUseless, described formula IV is: vUseless=vUseless 0+(UFref�CUF)/(t��VStep) (IV), wherein, vUseless: the rotating speed of the 3rd peristaltic pump motor; vUseless 0: the current rotating speed of the 3rd peristaltic pump motor; UFref: set ultrafiltration total amount; UF: actual ultrafiltration total amount; T: cumulative time; VStep: the flow that the 3rd peristaltic pump is every turn corresponding;
Step S106, adjustment motor speed is vUseless��
It is highly preferred that in above-mentioned steps S101, the instantaneous equivalent value of the described flow rate of liquid by first flow sensor or second flow sensor is calculated according to formula V, described formula V is: v=(Vot/Vmax)��vmax, wherein, v: the instantaneous equivalent value of flow rate of liquid;Vot: the instantaneous digital voltage signal of flow rate of liquid; Vmax: the digital voltage signal that liquid Peak Flow Rate is corresponding; vmax: liquid Peak Flow Rate equivalent value.
According to the principle to signal detection, at present the data of ultrasonic flow sensor are processed types such as substantially can dividing propagation speed differential method (including: directly time difference method, time difference method, relative mistake method, frequency-difference method), beam deviation method, Doppler method, method of correlation, spatial filtering method and Noise Method. May be applicable to this utility model.
In this utility model preferred embodiment, data processing unit is according to digital signal, by the integration of time calculates the accumulative total amount of liquid by ultrasonic flow sensor. The described integration to the time refers to, fixed time interval (such as 20ms but be not limited to 20ms) gathers primary transducer output signal, and be digital signal by AD conversion, digital signal value is converted to the moment equivalent value v (ml/min) of current liquid flow velocity again, by the time being integrated instantaneous valueDraw the accumulative total amount V (ml) of liquid in certain period of time. Due to the pulse characteristic of peristaltic pump, the non-constant flow velocity of liquid velocity through flow transducer, by such algorithm can maximum possible make value of calculation close to actual value, finally can pass through Compensation Method error.
Wherein, the digital voltage signal V that liquid Peak Flow Rate is correspondingmaxIt is preferably 5V, liquid Peak Flow Rate equivalent value vmaxBeing preferably 300ml/min, namely formula V is preferably: v=(Vot/ 5) �� 300. Specifically, the instantaneous digital voltage signal obtaining flow rate of liquid is calculated the instantaneous equivalent value of flow rate of liquid by data processing unit, the digital voltage signal 0V correspondence liquid minimum flow velocity equivalent value 0ml/min corresponding by obtaining liquid minimum flow velocity, the digital voltage signal 5V correspondence liquid Peak Flow Rate equivalent value 300ml/min corresponding by obtaining liquid Peak Flow Rate.
Formula I described in this utility model, in II, v1��v2Unit be preferably ml/min; The unit of t is preferably min; V1��V2Unit be preferably ml. In described formula V, the unit of v is preferably ml/min; VotUnit be preferably V; VmaxUnit be preferably V; vmaxUnit be preferably ml/min.
Those skilled in the art all understand, transfer the operation process of pump according to instruction, regulate the process of the rotating speed of pump according to flow detector flow signal as above, and send display signal according to the signal from each detector, and failure judgement concurrently send the process of alarm command, computer of the prior art, integrated circuit modules, PLD, other hardware or existing software module all can be utilized to realize.
In a preferred embodiment, described second peristaltic pump mechanism includes the second peristaltic pump and for driving the rotation of the second peristaltic pump concurrently to send the second peristaltic pump electric driver of motor speed feedback signal.
In one more preferably embodiment, described second peristaltic pump electric driver includes with lower part:
It is connected with the second peristaltic pump motor driver, for driving the rotation of the second peristaltic pump, and with negative feedback loop, sends the second peristaltic pump motor of motor speed feedback signal; Second peristaltic pump motor is motor;
It is connected with the second peristaltic pump motor, and controls the second peristaltic pump motor speed, receive the second peristaltic pump motor driver of the motor speed feedback signal that the second peristaltic pump motor sends.
In a preferred embodiment, described first peristaltic pump mechanism includes the first peristaltic pump and for driving the rotation of the first peristaltic pump concurrently to send the first peristaltic pump electric driver of motor speed feedback signal.
In one more preferably embodiment, described first peristaltic pump electric driver includes with lower part:
It is connected with the first peristaltic pump motor driver, for driving the rotation of the first peristaltic pump, and with negative feedback loop, sends the first peristaltic pump motor of motor speed feedback signal; First peristaltic pump motor is motor;
It is connected with the first peristaltic pump motor, and controls the first peristaltic pump motor speed, receive the first peristaltic pump motor driver of the motor speed feedback signal that the first peristaltic pump motor sends.
In a preferred embodiment, described 3rd peristaltic pump motor, the second peristaltic pump motor and the first peristaltic pump motor are motor. Described motor is with negative feedback loop, it is possible to send motor speed feedback signal. It is specially the AR series motor of east motor, essentially all of servo motor model number etc. On off control is accurate, can accurately detect electric machine rotation distance (number of motor steps).
Whether negative feedback loop described in this utility model is used for feeding back motor speed, and specifically, negative feedback loop gathers the actual step value of motor, exist lose the serious exception of step for monitoring motor. Peristaltic pump motor often makes a move and will provide a feedback pulse, feedback pulse that negative feedback loop is monitored by negative feedback control device also adds up, pulse conversion accumulative in unit interval is motor speed, and set rotating speed as reference value and theory and compare, if feedback loop motor speed value exceedes theory sets tachometer value certain limit, it is determined that seriously lose step, it is considered as electrical fault, it is necessary to do corresponding operation stopping motor rotation and check.
In a preferred embodiment, the interior intracavity of described filter 5 is provided with filter membrane, and filter 5 inner chamber is separated into the blood flowing space and dialysis solution/waste liquid flowing space by filter membrane; Described first pipeline 11 accesses the blood flowing space of filter 5, and described second pipeline 21 picks out from the blood flowing space of filter 5; 3rd pipeline 31 is selectively accessing the dialysis solution/waste liquid flowing space of filter 5 or the arbitrary of the blood flowing space, and described 4th pipeline 41 picks out from the dialysis solution of filter 5/waste liquid flowing space.
In one embodiment, described apparatus for purifying blood includes cooling system, and described cooling system includes the internal temperature for monitoring described apparatus for purifying blood and testing result sends the temperature sensor to described controller and fan. Described controller regulates and controls the operating of described fan according to the result of described temperature sensor monitors. The internally installed of described apparatus for purifying blood has multiple temperature sensor for monitoring device internal temperature, starts fan when temperature exceedes safety door limit value and lowers the temperature to device. The temperature of the internal diverse location of multiple temperature sensor harvesters, determines whether to reach system temperature secure setting by decision algorithm. Controller can set that multi-step temperature secure setting, be start one or multiple fan dispels the heat, Appropriate application for judgement, reduce Overall Power Consumption.
In one embodiment, described apparatus for purifying blood includes housing. Described housing adopts PC/ABS composite. This case material not only intensity is high but also light weight, meets portable use needs.
In one embodiment, described apparatus for purifying blood also includes being connected with described controller, for showing the display of the information of all parameters in described controller, warning, prompting and setting.
In one embodiment, described apparatus for purifying blood also includes power-supply system.
In this utility model, apparatus for purifying blood can pass through the flow of liquid in flow transducer, balance control device and the 3rd effective control piper of peristaltic pump mechanism, when using apparatus for purifying blood, it is possible to effectively control to reach fluid balance. The control mechanism that in this utility model, apparatus for purifying blood reaches to balance is: to ensure during dialysis treatment that the amount of liquid of turnover human body to ensure unanimously on the one hand, here it is described balance; Still further aspect sloughs the moisture that human body itself is unnecessary on this basis again, i.e. so-called ultrafiltration. If error occurs in balance system, then the liquid of human body just loses balance. Due to use peristaltic pump carry out human fluid replace time, difference and error due to peristaltic pump self, and the reason such as pump line soft durometer under various circumstances causes fortune to circle the different deviation caused of amount of liquid of output, only ensure that fluid balance is less reliable with peristaltic pump. A kind of feedback monitoring means of needs ensure that human body liquid in-out body balances. Traditional way is to use the mode that scale carries out weighing to guarantee turnover fluid balance, also has a kind of mode by counter balance pocket to guarantee turnover fluid balance. This utility model by use flow transducer monitoring flow, and feedback regulation pump reach turnover people liquid reach balance. Specifically, in this utility model the second peristaltic pump mechanism provide power to ensure together with the 3rd peristaltic pump mechanism liquid is circulated. Liquid is filled with in filter by the second peristaltic pump mechanism by dialysis solution/displacement liquid, again the liquid entering filter is extracted out by the 3rd peristaltic pump mechanism, need to be precisely controlled the second peristaltic pump mechanism and the 3rd peristaltic pump mechanism pump speed, to reach filter passes in and out the balance of liquid. Namely motor real-world operation speed is obtained by motor feedback signals on the one hand, simultaneously by flow transducer monitoring liquid actual flow, the speed of feedback adjustment pump is carried out by the difference between Sensor monitoring amount and motor feedback, guarantee that pump speed reaches setting speed value on the one hand, guarantee that the amount of liquid flowing through two pumps is equal on the other hand. This fluid balance is only suitable under hemodialysis pattern (HD) and hemofiltration mode (HF).
In preferred embodiment of the present utility model, in hemodialysis pattern, described dialysis solution is identical with the flow velocity of waste liquid, so that it is guaranteed that human fluid's balance, if desired for moisture unnecessary in extra ultrafiltration patient body, namely set ultrafiltration volume, then in the 3rd peristaltic pump mechanism that ultrasiltrated rate needs to be superimposed upon on waste liquid path, namely ultrasiltrated rate=the 3rd peristaltic pump speed the-the second peristaltic pump speed; Ultrafiltration volume=second flow sensor detection total amount-first flow sensor detection total amount.
In preferred embodiment of the present utility model, in hemofiltration pattern, displacement liquid is identical with the flow velocity of waste liquid, so that it is guaranteed that human fluid passes in and out balance, if desired for moisture unnecessary in extra ultrafiltration patient body, namely set ultrafiltration volume, then ultrasiltrated rate needs to be superimposed upon on the 3rd peristaltic pump of waste liquid path, namely ultrasiltrated rate=the 3rd peristaltic pump speed the-the second peristaltic pump speed; Ultrafiltration volume=second flow sensor detection total amount-first flow sensor total amount.
In preferred embodiment of the present utility model, in isolated ultrafiltration pattern, owing to the second peristaltic pump on dialysis solution/displacement liquid path shuts down, i.e. ultrasiltrated rate=the 3rd peristaltic pump speed; Ultrafiltration volume=second flow sensor detection total amount. So by pressure differential, moisture unnecessary in patient body is made to enter waste liquid side through the film in filter.
In preferred embodiment of the present utility model, in hemoperfusion pattern, it is not necessary to fluid balance, according only to absorption principle, macromolecule material in Filtration Adsorption blood.
More specifically, apparatus for purifying blood described above is capable of hemodialysis, blood filtration, hemoperfusion and four kinds of Therapeutic mode of ultrafiltration, the concrete How It Works of these four Therapeutic mode is as follows:
1) as it is shown in figure 1, hemodialysis pattern:
In such a mode, apparatus for purifying blood is provided with blood sampling tube, dialysis solution/displacement liquid path, blood back path and waste liquid logical
Road, adds dialysis solution before starting dialysis in memory unit. Specifically:
11) in dialysis solution/displacement liquid path, by the dialysis solution in the 3rd pipeline 31, under the second peristaltic pump mechanism 32 drives, through the first degasification kettle degasification, and after first flow sensor 33, the dialysis solution/waste liquid flowing space of filter 5 is flowed into;
12) blood of human body is inputted the first pipeline 11 in blood sampling tube by blood input port, under the first peristaltic pump mechanism 12 drives, after deaerated kettle degasification, flow into the blood flowing space of filter;
13) by step 11) flow into the dialysis solution of filter 5, with step 12) and flow into the blood of filter 5, carry out mass exchange inside and outside film, described dialysis solution and blood are in the flowing in opposite direction of described filter 5;
14) by step 13) blood after mass exchange, is flowed out by filter 5, flows into the second pipeline 21 in blood back path, after deaerated kettle degasification, by blood outlet, flow back to human body;
15) by step 13) waste liquid that produces after mass exchange, is flowed out by filter 5, flows into the 4th pipeline 41 in waste liquid path, under the 3rd peristaltic pump mechanism 42 drives, through the second degasification kettle degasification, discharged by waste liquid outlet;
2) as in figure 2 it is shown, hemofiltration pattern:
In such a mode, apparatus for purifying blood is provided with blood sampling tube, dialysis solution/displacement liquid path, blood back path and waste liquid logical
Road, adds displacement liquid before starting dialysis in memory unit. Specifically:
21) under the first peristaltic pump 12 drives, blood of human body is inputted the first pipeline 11 in blood sampling tube by blood input port;
22) in dialysis solution/displacement liquid path, by the displacement liquid in the 3rd pipeline 31, under the second peristaltic pump mechanism 32 drives, through the first degasification kettle degasification, after first flow sensor 33 carries out fluid balance, the first pipeline 11 is injected;
23) by step 21) in blood and step 22) in displacement liquid mix in the first pipeline 11 after, after deaerated kettle degasification, flow into filter 5 the blood flowing space filter;
24) by step 23) replace the blood after filtering, filter 5 flow out, flow into the second pipeline 21 in blood back path 2, after deaerated kettle degasification, by blood outlet, flow back to human body;
25) by step 23) replace the waste liquid produced after filtering, owing to producing pressure differential inside and outside the film of filter 5, dialysis solution/waste liquid flowing space is replaced by the blood flowing space of filter 5, and under the 3rd peristaltic pump 42 of waste liquid path drives, flow into the 4th pipeline 41 in waste liquid path, through the second degasification kettle degasification, discharged by waste liquid outlet;
3) as it is shown on figure 3, isolated ultrafiltration pattern:
In such a mode, apparatus for purifying blood is closed dialysis solution/displacement liquid path, opened blood sampling tube, blood back path and given up
Liquid path, specifically:
31) dialysis solution/displacement liquid path is closed;
32) by blood input port, blood of human body being inputted the first pipeline 11 in blood sampling tube, under the first peristaltic pump mechanism 12 drives, after deaerated kettle degasification, the blood flowing space flowing into filter 5 filters;
33) by step 32) filter after blood flow out filter 5, flow into the second pipeline 21 in blood back path, after deaerated kettle degasification, by blood outlet, flow back to human body;
34) by step 32) excessive moisture that produces after filtering blood, owing to producing pressure differential inside and outside the film of filter 5, dialysis solution/waste liquid flowing space is penetrated into by the blood flowing space of filter 5, and under the 3rd peristaltic pump mechanism 42 drives, flow into the 4th pipeline 41 in waste liquid path, through the second degasification kettle degasification, discharged by waste liquid outlet;
4) as shown in Figure 4, hemoperfusion pattern:
In such a mode, apparatus for purifying blood is closed dialysis solution/displacement liquid path, has opened blood sampling tube and blood back path, tool
Body ground:
41) dialysis solution/displacement liquid path and waste liquid path are closed;
42) blood of human body is inputted the first pipeline 11 in blood sampling tube 1 by blood input port, under the first peristaltic pump mechanism 12 drives, after deaerated kettle degasification, flow into the blood flowing space Filtration Adsorption of filter 5;
43) by step 42) blood after Filtration Adsorption flows out filter 5, and flow into the second pipeline 21 in blood back path, after deaerated kettle degasification, by blood outlet, flow back to human body.
In preferred embodiment of the present utility model, described degasification kettle degasification, is get rid of the bubble in liquid and blood.
Above-described embodiment only illustrative principle of the present utility model and effect thereof, not for restriction this utility model. Above-described embodiment all under spirit of the present utility model and category, can be modified or change by any those skilled in the art. Therefore, art has all equivalence modification or changes that usually intellectual completes under the spirit disclosed without departing from this utility model with technological thought such as, must be contained by claim of the present utility model.
Claims (21)
1. an apparatus for purifying blood, it is characterised in that: described apparatus for purifying blood includes blood sampling tube, blood back path, dialysis solution/displacement liquid path, waste liquid path, filter (5) and controller;
Described blood sampling tube, blood back path, dialysis solution path/displacement liquid path and waste liquid path be all dismountable and described filter is connected; Described blood sampling tube is provided with the first pipeline (11) and for providing the first peristaltic pump mechanism (12) of driving force for described first pipeline (11);
Described dialysis solution/displacement liquid path is provided with the 3rd pipeline (31), is used for providing the second peristaltic pump mechanism (32) of driving force and for monitoring the flow of liquid in described 3rd pipeline (31) in real time and by the first flow sensor (33) of monitoring result transmission to described controller for described 3rd pipeline (31);
Described waste liquid path is provided with the 4th pipeline (41), is used for providing the 3rd peristaltic pump mechanism (42) of driving force and for monitoring the flow of liquid in the 4th pipeline (41) in real time and by the second flow sensor (45) of monitoring result transmission to described controller for described 4th pipeline (41).
2. apparatus for purifying blood as claimed in claim 1, it is characterized in that: being additionally provided with anticoagulant syringe (14) on described blood sampling tube and for providing the anticoagulant syringe pump (13) of power to described anticoagulant syringe (14), described anticoagulant syringe (14) is connected with described first pipeline (11) by pipeline.
3. apparatus for purifying blood as claimed in claim 1, it is characterized in that: described blood sampling tube is additionally provided with for monitoring the pressure on described first pipeline (11), and monitoring result is sent pressure transducer (15) to the filter of described controller, before described filter, pressure transducer (15) is located between the first peristaltic pump mechanism (12) and described filter (5).
4. apparatus for purifying blood as claimed in claim 1, it is characterized in that: described blood sampling tube is additionally provided with arterial pressure sensor (16), the flow direction of liquid in the first pipeline (11) on described blood sampling tube, described arterial pressure sensor (16) is located at the upstream of described first peristaltic pump mechanism (12).
5. apparatus for purifying blood as claimed in claim 1, it is characterized in that: described blood back path includes the second pipeline (21), the liquid flow direction along described second pipeline (21) is provided with bubble detector (22) and venous check valve (23).
6. apparatus for purifying blood as claimed in claim 5, it is characterized in that: described blood back path is provided with the pressure for monitoring on described second pipeline (21) and monitoring result is sent the venous pressure sensor (24) to described controller, the flow direction of liquid in the second pipeline (21), described venous pressure sensor (24) is positioned at the upstream of described bubble detector (22).
7. apparatus for purifying blood as claimed in claim 1, it is characterized in that: the entrance being additionally provided with memory unit (34), described memory unit (34) and described 3rd pipeline (31) on described dialysis solution/displacement liquid path removably connects.
8. apparatus for purifying blood as claimed in claim 1, it is characterized in that: the 3rd pipeline (31) is additionally provided with the first degasification kettle, described first degasification kettle connects with described 3rd pipeline (31), and along the liquid flow direction in described 3rd pipeline (31), described first degasification kettle is positioned at the upstream of described first flow sensor (33).
9. apparatus for purifying blood as claimed in claim 1, it is characterized in that: described waste liquid path is provided with the pressure for monitoring on described 4th pipeline (41) and monitoring result is sent the waste liquid pressure transducer (44) to described controller, the flow direction of liquid in described 4th pipeline (41), described waste liquid pressure transducer (44) is located at the upstream of described 3rd peristaltic pump mechanism (42).
10. apparatus for purifying blood as claimed in claim 1, it is characterized in that: described waste liquid path is additionally provided with Lou blood sensor (43), along the flow direction of the upper liquid of described 4th pipeline (41), described leakage blood sensor (43) is located at the upstream of described 3rd peristaltic pump mechanism (42).
11. apparatus for purifying blood as claimed in claim 1, it is characterized in that: described waste liquid path is additionally provided with the second degasification kettle, described second degasification kettle connects with described 4th pipeline (41), and along the liquid flow direction in described 4th pipeline (41), described second degasification kettle is positioned at the upstream of described second flow sensor (45).
12. apparatus for purifying blood as claimed in claim 1, it is characterised in that: described first flow sensor (33) and second flow sensor (45) are ultrasonic flow sensor, and described ultrasonic flow sensor includes with lower component:
For ultrasonic flow sensor being fixed on the fixing parts on the 3rd pipeline (31) or the 4th pipeline (41);
It is arranged on the side of pipeline (31/41) in order to launch hyperacoustic ultrasonic transmitter to pipeline (31/41);
The opposite side being arranged on pipeline (31/41) is relative to ultrasonic transmitter to receive from described ultrasonic transmitter and to be transferred to the ultrasonic signal of ultrasonic receiver the ultrasonic receiver of output current signal.
13. apparatus for purifying blood as claimed in claim 1, it is characterised in that: described apparatus for purifying blood also includes the metering device for the signal sent calculated flow rate output flow signal receiving described first flow sensor (33) and second flow sensor (45).
14. apparatus for purifying blood as claimed in claim 13, it is characterised in that: described metering device includes with lower part:
For the current signal from flow transducer being converted to the signaling conversion circuit of voltage signal;
It is connected with signaling conversion circuit and is used for being reconverted into voltage signal the signal acquisition circuit of digital signal;
The data processing unit of output stream value is calculated after being connected with signal acquisition circuit and being used for receiving digital signal.
15. apparatus for purifying blood as claimed in claim 13, it is characterised in that: described 3rd peristaltic pump mechanism includes the 3rd peristaltic pump and for driving described 3rd peristaltic pump to rotate the 3rd peristaltic pump electric driver concurrently sending motor speed feedback signal; Described apparatus for purifying blood includes:
It is connected with metering device and the 3rd peristaltic pump electric driver, receive the flow signal of automatic measurer and from the motor speed feedback signal of the 3rd peristaltic pump electric driver, and send the balance control device of motor speed control signal to the 3rd peristaltic pump electric driver.
16. apparatus for purifying blood as claimed in claim 15, it is characterised in that: described 3rd peristaltic pump electric driver includes with lower part:
It is connected with the 3rd peristaltic pump motor driver, for driving the rotation of the 3rd peristaltic pump, and with being used for sending the 3rd peristaltic pump motor of the negative feedback loop of motor speed feedback signal; Described 3rd peristaltic pump motor is motor;
It is connected with the 3rd peristaltic pump motor and balance control device, receiving balance controls the motor speed control signal of device transmission and controls the 3rd peristaltic pump motor speed, receives the motor speed feedback signal that the 3rd peristaltic pump motor sends the 3rd peristaltic pump motor driver being transferred to balance control device.
17. apparatus for purifying blood as claimed in claim 15, it is characterised in that: described balance control device includes with lower part:
For calculating the actual ultrafiltration total amount calculating unit obtaining actual ultrafiltration total amount;
For setting the setting ultrafiltration total amount unit of ultrafiltration total amount;
It is connected with the 3rd peristaltic pump electric driver, receives the signal feedback unit of the motor speed feedback signal from the 3rd peristaltic pump electric driver;
It is connected with actual ultrafiltration total amount calculating unit, setting ultrafiltration total amount unit and signal feedback unit respectively, calculates the 3rd peristaltic pump adjustment of rotational speed computing unit of the motor speed of the 3rd peristaltic pump mechanism (42);
It is connected with the 3rd peristaltic pump adjustment of rotational speed computing unit and the 3rd peristaltic pump electric driver, sends the signal transmitting unit of the motor speed control signal adjusting motor speed to the 3rd peristaltic pump electric driver.
18. apparatus for purifying blood as claimed in claim 5, it is characterised in that: the interior intracavity of described filter (5) is provided with filter membrane, and filter (5) inner chamber is separated into the blood flowing space and dialysis solution/waste liquid flowing space by filter membrane; Described first pipeline (11) accesses the blood flowing space of filter (5), and described second pipeline (21) picks out from the blood flowing space of filter (5); 3rd pipeline (31) is selectively accessing the dialysis solution/waste liquid flowing space of filter (5) or the arbitrary of the blood flowing space, and described 4th pipeline (41) picks out from the dialysis solution/waste liquid flowing space of filter (5).
19. apparatus for purifying blood as claimed in claim 1, it is characterized in that: described apparatus for purifying blood includes cooling system, described cooling system includes temperature sensor and fan, and described temperature sensor is for monitoring the internal temperature of described apparatus for purifying blood and sending testing result to described controller; Described controller regulates and controls the operating of described fan according to the result of described temperature sensor monitors.
20. apparatus for purifying blood as claimed in claim 1, it is characterised in that: described apparatus for purifying blood includes housing.
21. as claimed in claim 1 apparatus for purifying blood, it is characterised in that: described apparatus for purifying blood includes being connected with described controller, for showing the display of the information of all parameters in described controller, warning, prompting and setting.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201521035244.XU CN205287055U (en) | 2015-12-10 | 2015-12-10 | Blood purification device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201521035244.XU CN205287055U (en) | 2015-12-10 | 2015-12-10 | Blood purification device |
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| CN205287055U true CN205287055U (en) | 2016-06-08 |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105363085A (en) * | 2015-12-10 | 2016-03-02 | 威海威高血液净化制品有限公司 | Blood purification device |
| CN107281570A (en) * | 2017-07-27 | 2017-10-24 | 北京海洁海斯健康科技有限公司 | The self-cleaning system of new haemodialysis control unit |
| WO2018053779A1 (en) * | 2016-09-23 | 2018-03-29 | 四川大学 | Wearable filtering artificial kidney |
| CN112618819A (en) * | 2021-01-07 | 2021-04-09 | 上海药明康德新药开发有限公司 | Novel automatic blood sampling instrument and blood sampling method design |
-
2015
- 2015-12-10 CN CN201521035244.XU patent/CN205287055U/en active Active
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105363085A (en) * | 2015-12-10 | 2016-03-02 | 威海威高血液净化制品有限公司 | Blood purification device |
| CN105363085B (en) * | 2015-12-10 | 2018-05-22 | 威海威高血液净化制品有限公司 | Apparatus for purifying blood |
| WO2018053779A1 (en) * | 2016-09-23 | 2018-03-29 | 四川大学 | Wearable filtering artificial kidney |
| CN107281570A (en) * | 2017-07-27 | 2017-10-24 | 北京海洁海斯健康科技有限公司 | The self-cleaning system of new haemodialysis control unit |
| CN112618819A (en) * | 2021-01-07 | 2021-04-09 | 上海药明康德新药开发有限公司 | Novel automatic blood sampling instrument and blood sampling method design |
| CN112618819B (en) * | 2021-01-07 | 2022-02-22 | 上海药明康德新药开发有限公司 | Novel automatic blood sampling instrument and blood sampling method design |
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Address after: No.20, Xingshan Road, Weihai Torch hi tech Industrial Development Zone, Weihai City, Shandong Province, 264210 Patentee after: Shandong Weigao blood purification products Co.,Ltd. Address before: No.20, Xingshan Road, Weihai Torch hi tech Industrial Development Zone, Weihai City, Shandong Province, 264210 Patentee before: WEIHAI WEIGAO BLOOD PURIFICATION PRODUCTS Co.,Ltd. |