CN101338056A - Acrylic resin for manufacturing syringes for medical use - Google Patents
Acrylic resin for manufacturing syringes for medical use Download PDFInfo
- Publication number
- CN101338056A CN101338056A CNA2007100433718A CN200710043371A CN101338056A CN 101338056 A CN101338056 A CN 101338056A CN A2007100433718 A CNA2007100433718 A CN A2007100433718A CN 200710043371 A CN200710043371 A CN 200710043371A CN 101338056 A CN101338056 A CN 101338056A
- Authority
- CN
- China
- Prior art keywords
- acrylic resin
- butyl
- antioxidant
- resin
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
Polypropylene resin used for manufacturing medical injectors is composition, and the components comprise resin binders, transparent nucleating agents, acid neutralizers and antioxidants; wherein, the resin binders are random copolymer of propylene and ethylene, the ethylene content of the resin binder is 0.5 percent to 5 percent, and the transparent nucleating agents are sorbitol compounds; the acid neutralizers are one or the mixture of calcium stearate and hydrogenated talcum powders, the antioxidants are one or the mixture of hindered phenolic antioxidants and phosphate antioxidants. The invention has the characteristics that the transparent nucleating agents are the mixture of three (3, 4-dimethyl diphenyl methylene) sorbitol and bis (p-methylbenzylidene) sorbitol, and the ratio of the three (3,4-dimethyl diphenyl methylene) sorbitol and the bis (p- methylbenzylidene) sorbitol by the weight ratio is equal to 1 : 0.7 to 1.5. Compared with the prior art, the transparency of the resin which is provided by the invention is further improved on the premise that the favorable toughness of the resin is guaranteed.
Description
Technical field
The present invention relates to a kind of acrylic resin, particularly be exclusively used in the acrylic resin of making injector for medical purpose.
Background technology
In the prior art, the plastics injector for medical purpose generally adopts acrylic resin to make, and according to this special purposes of injector for medical purpose, the transparency and the toughness of the material that is used to make is all had higher requirement.Generally increase the transparency of material at present by adding nucleator, thickness is that the sheet material turbidity of 1.3mm can reach below 15%, but usually nucleator adds the toughness that affiliation influences material, therefore, the notched Izod impact strength that generally is used to make the medical syringe acrylic resin is about 20J/M, and the syringe of making more easily breaks.Application number provides a kind of acrylic resin that is used to make medical syringe for 200410017403.3 Chinese patent application, its notched Izod impact strength reaches as high as 90J/M, thickness is that the sheet material turbidity of 1.3mm can be about 8%, yet, guaranteeing that the further transparency that improves resin obviously is favourable for the quality of improving syringe products under the good toughness prerequisite.
Summary of the invention
The invention provides a kind of acrylic resin of making injector for medical purpose, the technical problem that it will solve is to guarantee that resin has under the good toughness prerequisite, has better transparency simultaneously.
Below be the technical scheme that the present invention solves the problems of the technologies described above:
A kind of acrylic resin of making injector for medical purpose, this acrylic resin are composition, and its component comprises resin binder, transparent nucleater, acid neutralizing agent and oxidation inhibitor.Wherein resin binder is propylene and ethylene atactic copolymer, ethylene content 0.5～5wt%, 140～165 ℃ of melt temperatures, melt flow rate (MFR) 6.0～30.0g/10min; Transparent nucleater is the glucitols compound; Acid neutralizing agent is a kind of in calcium stearate or the hydrogenation talcum powder or both mixtures; Oxidation inhibitor is a kind of in Hinered phenols antioxidant or the phosphite ester kind antioxidant or both mixtures.
In weight ratio, the ratio of each component is:
Resin binder: transparent nucleater=100: 0.08～0.40;
Resin binder: acid neutralizing agent=100: 0.01～0.10;
Resin binder: oxidation inhibitor=100: 0.02～0.30.
Above-mentioned transparent nucleater is three (3,4-dimethyl diphenylmethylene) mixture of sorbyl alcohol and two (to the methyldiphenyl methylene radical) sorbyl alcohol, in weight ratio, three (3,4-dimethyl diphenylmethylene) sorbyl alcohol: two (to the methyldiphenyl methylene radical) sorbyl alcohol=1: 0.7～1.5.
Above-mentioned oxidation inhibitor is preferably the mixture of Hinered phenols antioxidant and phosphite ester kind antioxidant, and the weight ratio of Hinered phenols antioxidant and phosphite ester kind antioxidant is 1: 0.2～8.
Above-mentioned Hinered phenols antioxidant preferably takes from 1,3,5-trimethylammonium-2,4,6-three (3,5-di-t-butyl-4 hydroxybenzyl) a kind of in benzene, two-[3,3-two-(3-tert-butyl-hydroxy phenyl)-butyric acid] glycol ester or four [β-(3, the 5-di-tert-butyl-hydroxy phenyl) propionic acid] pentaerythritol ester; Phosphite ester kind antioxidant is preferably taken from three (2, the 4-di-tert-butyl-phenyl) phosphorous acid esters or two (2, the 4-di-tert-butyl-phenyl) pentaerythritol esters of diphosphorous acid.
Compared with prior art, key of the present invention has been to select suitable acid neutralizing agent, oxidation inhibitor and transparent nucleater, and transparent nucleater has been carried out the improvement of compounded combination.The contriver found through experiments, and this combination makes resin guarantee that the transparency has had further raising under the good toughness prerequisite, and thickness is that the sheet material turbidity of 1.3mm can reach below 8%.Therefore, the present invention compared with prior art has tangible advantage.
Below will the invention will be further described by specific embodiment.
Embodiment
[embodiment 1]
Resin binder is propylene and ethylene atactic copolymer:
Ethylene content 0.2wt%, 160～165 ℃ of melt temperatures, melt flow rate (MFR) 8.0g/10min;
Acid neutralizing agent is a calcium stearate; Oxidation inhibitor is 1,3,5-trimethylammonium-2,4,6-three (3,5-di-t-butyl-4 hydroxybenzyl) benzene;
In weight ratio, the proportioning of transparent nucleater is:
Three (3,4-dimethyl diphenylmethylene) sorbyl alcohol: two (to the methyldiphenyl methylene radical) sorbyl alcohol=1: 0.7.
Proportioning between each component sees Table 1.
[embodiment 2]
The proportioning of transparent nucleater is:
Three (3,4-dimethyl diphenylmethylene) sorbyl alcohol: two (to the methyldiphenyl methylene radical) sorbyl alcohol=1: 1.2.
All the other are with embodiment 1.
[embodiment 3]
The proportioning of transparent nucleater is:
Three (3,4-dimethyl diphenylmethylene) sorbyl alcohol: two (to the methyldiphenyl methylene radical) sorbyl alcohol=1: 0.9.
All the other are with embodiment 1.
[embodiment 4]
The proportioning of transparent nucleater is:
Three (3,4-dimethyl diphenylmethylene) sorbyl alcohol: two (to the methyldiphenyl methylene radical) sorbyl alcohol=1: 1.5.
All the other are with embodiment 1.
[embodiment 5]
Resin binder is propylene and ethylene atactic copolymer:
Ethylene content 0.5wt%, 150～165 ℃ of melt temperatures, melt flow rate (MFR) 12g/10min;
Acid neutralizing agent is the hydrogenation talcum powder; Oxidation inhibitor is three (2, the 4-di-tert-butyl-phenyl) phosphorous acid ester;
The proportioning of transparent nucleater is:
Three (3,4-dimethyl diphenylmethylene) sorbyl alcohol: two (to the methyldiphenyl methylene radical) sorbyl alcohol=1: 1.
All the other are with embodiment 1.
[embodiment 6]
Resin binder is propylene and ethylene atactic copolymer:
Ethylene content 2.9wt%, 140～165 ℃ of melt temperatures, melt flow rate (MFR) 20g/10min;
Acid neutralizing agent is the hydrogenation talcum powder; Oxidation inhibitor is two-[3,3-two-(3-tert-butyl-hydroxy phenyl)-butyric acid] glycol esters:
The proportioning of transparent nucleater is:
Three (3,4-dimethyl diphenylmethylene) sorbyl alcohol: two (to the methyldiphenyl methylene radical) sorbyl alcohol=1: 1.1.
All the other are with embodiment 1.
It is 2 listed that the physical index of the various embodiments described above acrylic resin sees Table.
Table 1.
| Resin binder: transparent nucleater (weight ratio) | Resin binder: acid neutralizing agent (weight ratio) | Resin binder: oxidation inhibitor (weight ratio) | |
| Embodiment 1 | 100∶0.08 | 100∶0.01 | 100∶0.30 |
| Embodiment 2 | 100∶0.10 | 100∶0.10 | 100∶0.10 |
| Embodiment 3 | 100∶0.25 | 100∶0.07 | 100∶0.25 |
| Embodiment 4 | 100∶0.38 | 100∶0.06 | 100∶0.15 |
| Embodiment 5 | 100∶0.30 | 100∶0.05 | 100∶0.08 |
| Embodiment 6 | 100∶0.40 | 100∶0.09 | 100∶0.02 |
Table 2.
| Tensile strength (MPa) | Modulus in flexure (GPa) | Socle girder notched Izod impact strength (J/M) | Turbidity (%, thick 1.3mm sheet material) | |
| Embodiment 1 | 32.2 | 1.33 | 56 | 7.5 |
| Embodiment 2 | 31.8 | 1.28 | 58 | 7.1 |
| Embodiment 3 | 30.9 | 1.56 | 67 | 7.0 |
| Embodiment 4 | 35.2 | 1.66 | 55 | 6.8 |
| Embodiment 5 | 34.1 | 1.45 | 70 | 6.9 |
| Embodiment 6 | 30.6 | 1.20 | 95 | 6.4 |
Claims (4)
1, a kind of acrylic resin of making injector for medical purpose, this acrylic resin is a composition, its component comprises resin binder, transparent nucleater, acid neutralizing agent and oxidation inhibitor, wherein resin binder is propylene and ethylene atactic copolymer, ethylene content 0.5～5wt%, 140～165 ℃ of melt temperatures, melt flow rate (MFR) 6.0～30.0g/10min; Transparent nucleater is the glucitols compound; Acid neutralizing agent is a kind of in calcium stearate or the hydrogenation talcum powder or both mixtures; Oxidation inhibitor is a kind of in Hinered phenols antioxidant or the phosphite ester kind antioxidant or both mixtures,
In weight ratio, the ratio of each component is:
Resin binder: transparent nucleater=100: 0.08～0.40;
Resin binder: acid neutralizing agent=100: 0.01～0.10;
Resin binder: oxidation inhibitor=100: 0.02～0.30,
It is characterized in that transparent nucleater is three (3,4-dimethyl diphenylmethylene) mixture of sorbyl alcohol and two (to the methyldiphenyl methylene radical) sorbyl alcohol, in weight ratio, three (3,4-dimethyl diphenylmethylene) sorbyl alcohol: two (to the methyldiphenyl methylene radical) sorbyl alcohol=1: 0.7～1.5.
2, acrylic resin according to claim 1 is characterized in that described oxidation inhibitor is the mixture of Hinered phenols antioxidant and phosphite ester kind antioxidant, and the weight ratio of Hinered phenols antioxidant and phosphite ester kind antioxidant is 1: 0.2～8.
3, acrylic resin according to claim 1 and 2, it is characterized in that described Hinered phenols antioxidant takes from 1,3,5-trimethylammonium-2,4,6-three (3,5-di-t-butyl-4 hydroxybenzyl) benzene, two-[3,3-two-(3-tert-butyl-hydroxy phenyl)-butyric acid] a kind of in glycol ester or four [β-(3, the 5-di-tert-butyl-hydroxy phenyl) propionic acid] pentaerythritol ester.
4, acrylic resin according to claim 1 and 2 is characterized in that described phosphite ester kind antioxidant takes from two (2, the 4-di-tert-butyl-phenyl) pentaerythritol esters of three (2, the 4-di-tert-butyl-phenyl) phosphorous acid esters or diphosphorous acid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007100433718A CN101338056A (en) | 2007-07-03 | 2007-07-03 | Acrylic resin for manufacturing syringes for medical use |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007100433718A CN101338056A (en) | 2007-07-03 | 2007-07-03 | Acrylic resin for manufacturing syringes for medical use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101338056A true CN101338056A (en) | 2009-01-07 |
Family
ID=40212232
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2007100433718A Pending CN101338056A (en) | 2007-07-03 | 2007-07-03 | Acrylic resin for manufacturing syringes for medical use |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101338056A (en) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102391585A (en) * | 2011-10-08 | 2012-03-28 | 中国石油化工股份有限公司 | Polypropylene material for transparent bottles and preparation method thereof |
| CN102492226A (en) * | 2011-12-05 | 2012-06-13 | 大连兴辉化工有限公司 | Special additive SYNOXM4228 for copolymerized polypropylene tube material and application thereof |
| CN102516672A (en) * | 2011-11-14 | 2012-06-27 | 江苏金发科技新材料有限公司 | Beta crystal form ethylene propylene polypropylene random copolymer composite and preparation method thereof |
| CN102757601A (en) * | 2012-08-01 | 2012-10-31 | 长沙达联塑料有限公司 | Polypropylene transparent masterbatch material and preparation method |
| CN103030886A (en) * | 2012-12-20 | 2013-04-10 | 中国石油天然气股份有限公司 | Transparent polypropylene and preparing method thereof |
| CN103834099A (en) * | 2012-11-27 | 2014-06-04 | 中国石油天然气股份有限公司 | Special medical irradiation-resistant polypropylene material |
| CN107540953A (en) * | 2016-06-28 | 2018-01-05 | 中国石油化工股份有限公司 | Injector for medical purpose polypropylene resin composite and preparation method thereof |
| CN107880404A (en) * | 2016-09-29 | 2018-04-06 | 中国石油化工股份有限公司 | A kind of high-flowability polypropylene resin for the manufacture of disposable medical syringe and preparation method thereof |
| GB2549504B (en) * | 2016-04-19 | 2020-03-04 | Njc Europe Ltd | Method for identifying a blend of nucleators useful for preparing a nucleated polyolefin material |
| CN111138752A (en) * | 2018-11-05 | 2020-05-12 | 苏州市朗腾工贸有限公司 | Medical large infusion polypropylene material modification process |
-
2007
- 2007-07-03 CN CNA2007100433718A patent/CN101338056A/en active Pending
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102391585B (en) * | 2011-10-08 | 2013-06-26 | 中国石油化工股份有限公司 | Polypropylene material for transparent bottles and preparation method thereof |
| CN102391585A (en) * | 2011-10-08 | 2012-03-28 | 中国石油化工股份有限公司 | Polypropylene material for transparent bottles and preparation method thereof |
| CN102516672A (en) * | 2011-11-14 | 2012-06-27 | 江苏金发科技新材料有限公司 | Beta crystal form ethylene propylene polypropylene random copolymer composite and preparation method thereof |
| CN102492226A (en) * | 2011-12-05 | 2012-06-13 | 大连兴辉化工有限公司 | Special additive SYNOXM4228 for copolymerized polypropylene tube material and application thereof |
| CN102757601A (en) * | 2012-08-01 | 2012-10-31 | 长沙达联塑料有限公司 | Polypropylene transparent masterbatch material and preparation method |
| CN103834099A (en) * | 2012-11-27 | 2014-06-04 | 中国石油天然气股份有限公司 | Special medical irradiation-resistant polypropylene material |
| CN103030886A (en) * | 2012-12-20 | 2013-04-10 | 中国石油天然气股份有限公司 | Transparent polypropylene and preparing method thereof |
| GB2549504B (en) * | 2016-04-19 | 2020-03-04 | Njc Europe Ltd | Method for identifying a blend of nucleators useful for preparing a nucleated polyolefin material |
| US11733189B2 (en) | 2016-04-19 | 2023-08-22 | Njc Europe Limited | Method for identifying a blend of nucleators useful for preparing a nucleated polyolefin material |
| CN107540953A (en) * | 2016-06-28 | 2018-01-05 | 中国石油化工股份有限公司 | Injector for medical purpose polypropylene resin composite and preparation method thereof |
| CN107540953B (en) * | 2016-06-28 | 2020-04-14 | 中国石油化工股份有限公司 | Polypropylene resin composition for medical syringe and preparation method thereof |
| CN107880404A (en) * | 2016-09-29 | 2018-04-06 | 中国石油化工股份有限公司 | A kind of high-flowability polypropylene resin for the manufacture of disposable medical syringe and preparation method thereof |
| CN111138752A (en) * | 2018-11-05 | 2020-05-12 | 苏州市朗腾工贸有限公司 | Medical large infusion polypropylene material modification process |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101338056A (en) | Acrylic resin for manufacturing syringes for medical use | |
| EP2178975B1 (en) | Polyester mixture with improved flowability and good mechanical properties | |
| EP1451251B1 (en) | Transparent styrol-butadiene block copolymer mixtures | |
| CN102367308B (en) | Flame retardant polypropylene composite material and its preparation method | |
| CN102140224B (en) | Halogen-free inflaming retarding thermoplastic elastomer for secondary injection adhering and preparation method thereof | |
| CN101338055A (en) | Acrylic resin for manufacturing medical infusion bottle | |
| CN107540953B (en) | Polypropylene resin composition for medical syringe and preparation method thereof | |
| CN103834099A (en) | Special medical irradiation-resistant polypropylene material | |
| CN103012952A (en) | Polypropylene thermoplastic elastomer for automobile safety airbag cover board and preparation method thereof | |
| DE102014217345A1 (en) | Long fiber reinforced thermoplastic resin composition having improved impact resistance and molded product using the same | |
| CN101760001A (en) | Thermoplastic elastomer composition for bonding ABS and preparation method thereof | |
| EP1669407A1 (en) | Transparent mixtures of linear styrene-butadiene-blockcopolymers | |
| CN101724203A (en) | Polypropylene resin suitable for manufacturing medical infusion bottle by using injection stretch blow moulding process | |
| WO2010103988A1 (en) | Elastomer composition for medical container stopper | |
| CN1676545A (en) | Polypropylene resin for manufacturing medical syringe | |
| CN101302140B (en) | Method for preventing alkylphenol from discoloration | |
| CN105837909A (en) | Cold-resistant polyethylene material | |
| CN107841052B (en) | Polypropylene composition, polypropylene material and application thereof | |
| CN106905614A (en) | A kind of high rigidity polypropene composition | |
| CN108384113A (en) | A kind of polypropylene/polyphenylene oxide alloy and preparation method thereof | |
| CN101724200A (en) | Polypropylene resin used for manufacturing medical infusion bottle by injection stretch blow moulding | |
| CN101724199A (en) | Preparation method of polypropylene resin used for manufacturing medical infusion bottle by injection stretch blow moulding | |
| CN109320827B (en) | Polyethylene resin suitable for preparing blow molding tray and preparation method and application thereof | |
| EP1537172B1 (en) | Stabilised block copolymers made from styrol monomers and diene monomers | |
| CN107841053B (en) | Polypropylene composition, polypropylene material and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20090107 |