CN101336297B - 细胞内线粒体的极化监控 - Google Patents

细胞内线粒体的极化监控 Download PDF

Info

Publication number
CN101336297B
CN101336297B CN2006800520438A CN200680052043A CN101336297B CN 101336297 B CN101336297 B CN 101336297B CN 2006800520438 A CN2006800520438 A CN 2006800520438A CN 200680052043 A CN200680052043 A CN 200680052043A CN 101336297 B CN101336297 B CN 101336297B
Authority
CN
China
Prior art keywords
change
variation
cells
mitochondrial
viable cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2006800520438A
Other languages
English (en)
Chinese (zh)
Other versions
CN101336297A (zh
Inventor
小名俊博
小齐平笃
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyushu University NUC
Original Assignee
Kyushu University NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyushu University NUC filed Critical Kyushu University NUC
Publication of CN101336297A publication Critical patent/CN101336297A/zh
Application granted granted Critical
Publication of CN101336297B publication Critical patent/CN101336297B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5035—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on sub-cellular localization
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G01N21/553—Attenuated total reflection and using surface plasmons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CN2006800520438A 2005-12-14 2006-12-14 细胞内线粒体的极化监控 Expired - Fee Related CN101336297B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP360458/2005 2005-12-14
JP2005360458 2005-12-14
PCT/JP2006/324960 WO2007069692A1 (ja) 2005-12-14 2006-12-14 細胞内ミトコンドリアの分極モニタリング

Publications (2)

Publication Number Publication Date
CN101336297A CN101336297A (zh) 2008-12-31
CN101336297B true CN101336297B (zh) 2011-09-07

Family

ID=38162994

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2006800520438A Expired - Fee Related CN101336297B (zh) 2005-12-14 2006-12-14 细胞内线粒体的极化监控

Country Status (5)

Country Link
US (1) US20110003321A1 (https=)
EP (1) EP1961824A4 (https=)
JP (2) JP5486768B2 (https=)
CN (1) CN101336297B (https=)
WO (1) WO2007069692A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009122016A (ja) * 2007-11-16 2009-06-04 Kyushu Univ 判定装置、選定装置、判定方法、細胞生産方法、プログラム及び記録媒体
JP5808772B2 (ja) * 2013-05-13 2015-11-10 株式会社エヌ・エル・エー 肝細胞内のミトコンドリアの活性化方法
CN112881355B (zh) * 2021-01-17 2022-03-18 复旦大学 用于细胞内pH和氧气浓度同时测量的双参数荧光纳米传感器及其制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002085089A (ja) * 2000-09-06 2002-03-26 Japan Science & Technology Corp 細胞活性の評価方法
WO2004042079A1 (en) * 2002-11-07 2004-05-21 Unisearch Limited Induction of the mitochondrial permeability transition
WO2005001472A1 (ja) * 2003-06-25 2005-01-06 Japan Science And Technology Agency 抗がん作用物質のスクリーニング方法及び装置

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002085089A (ja) * 2000-09-06 2002-03-26 Japan Science & Technology Corp 細胞活性の評価方法
WO2004042079A1 (en) * 2002-11-07 2004-05-21 Unisearch Limited Induction of the mitochondrial permeability transition
WO2005001472A1 (ja) * 2003-06-25 2005-01-06 Japan Science And Technology Agency 抗がん作用物質のスクリーニング方法及び装置

Also Published As

Publication number Publication date
CN101336297A (zh) 2008-12-31
US20110003321A1 (en) 2011-01-06
EP1961824A4 (en) 2009-04-08
JP2012093369A (ja) 2012-05-17
WO2007069692A1 (ja) 2007-06-21
JP5486768B2 (ja) 2014-05-07
JPWO2007069692A1 (ja) 2009-05-28
EP1961824A1 (en) 2008-08-27
JP5514233B2 (ja) 2014-06-04

Similar Documents

Publication Publication Date Title
Ye et al. Smart contact lens with dual‐sensing platform for monitoring intraocular pressure and matrix metalloproteinase‐9
Munan et al. PET-and ICT-based ratiometric probe: an unusual phenomenon of morpholine-conjugated fluorophore for mitochondrial pH mapping during mitophagy
Semba et al. The role of O‐GlcNAc signaling in the pathogenesis of diabetic retinopathy
Ha et al. Tnfaip8 l1/Oxi‐β binds to FBXW 5, increasing autophagy through activation of TSC 2 in a Parkinson's disease model
Marcelo et al. Cordycepin activates autophagy through AMPK phosphorylation to reduce abnormalities in Machado–Joseph disease models
Li et al. Astrocyte VAMP3 vesicles undergo Ca2+‐independent cycling and modulate glutamate transporter trafficking
Wu et al. Real-time evaluation of live cancer cells by an in situ surface plasmon resonance and electrochemical study
Han et al. Specific detection of aquaporin-2 using plasmonic tilted fiber grating sensors
Han et al. Mitochondrial-targeted ratiometric near-infrared fluorescence probe for monitoring nitric oxide in rheumatoid arthritis
WO2021087145A1 (en) Human cellular model for investigating cortico-striatal-midbrain neural pathways
Xiao-hong et al. An evanescent wave multi-channel immunosensor system for the highly sensitive detection of small analytes in water samples
CN102549430A (zh) 表征细胞重编程的方法及其应用
US20170059557A1 (en) Mechanical stress response analysis of cells and tissues
JP5514233B2 (ja) 細胞内ミトコンドリアの分極モニタリング
Zieliński et al. Changes in nanomechanical properties of single neuroblastoma cells as a model for oxygen and glucose deprivation (OGD)
CN110759985B (zh) 一种用于微波辐射致神经元钙信号调节的生物标志物Orai2蛋白
Karpova et al. Integration of nuclear Ca2+ transients and subnuclear protein shuttling provides a novel mechanism for the regulation of CREB-dependent gene expression
Cheng et al. Memantine attenuates the development of osteoarthritis by blocking NMDA receptor mediated calcium overload and chondrocyte senescence
Li et al. Interaction of AR and iNOS in lens epithelial cell: a new pathogenesis and potential therapeutic targets of diabetic cataract
Adnan et al. Investigating role of plumbagin in preventing neurodegenerative diseases via inhibiting microtubule affinity regulating kinase 4
Ma et al. βA3/A1-Crystallin controls anoikis-mediated cell death in astrocytes by modulating PI3K/AKT/mTOR and ERK survival pathways through the PKD/Bit1-signaling axis
Yang et al. On chip detection of glial cell-derived neurotrophic factor secreted from dopaminergic cells under magnetic stimulation
Sun et al. PI4P-dependent targeting of ATG14 to mature autophagosomes
Sripathi et al. Nitric oxide leads to cytoskeletal reorganization in the retinal pigment epithelium under oxidative stress
Wang et al. Pericyte biomarkers for ischemic stroke: potential and prospects

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20110907

Termination date: 20131214