CN101305753A - Immune regulation nutrient edible oil and its preparation method - Google Patents
Immune regulation nutrient edible oil and its preparation method Download PDFInfo
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- CN101305753A CN101305753A CNA2007100406640A CN200710040664A CN101305753A CN 101305753 A CN101305753 A CN 101305753A CN A2007100406640 A CNA2007100406640 A CN A2007100406640A CN 200710040664 A CN200710040664 A CN 200710040664A CN 101305753 A CN101305753 A CN 101305753A
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Abstract
The invention discloses immunoregulation nutritious edible oil. The edible oil contains 60-162 mg of vitamin E and 60-300 g of tea polyphenols (calculated based on catechin) per 100g of the oil. The invention also discloses the preparation method of the edible oil, which comprises the steps of mixing the edible oil, vitamin E and tea polyphenols, stirring, filtering, filling with nitrogen, and canning. A function test indicates that the nutritious edible oil has immunoregulation effect, and has important significances for improving the body immunity and the human body sub-health status after long-term administration. The 18-month guarantee period of the edible oil can be ensured and the nutritive elements such as vitamin E and tea polyphenols have effective dose of immunoregulation using nitrogen filling fresh-keeping process without adding any artificial antioxidant in the guarantee period. In addition, the nutritious edible oil has high quality and low cost, and is suitable for common consumers.
Description
Technical field
Patent of the present invention relates to a kind of edible oil, relates in particular to a kind of nutrient edible oil with immunoregulation effect.
Background technology
Along with the development of society, the quickening of rhythm of life, the modern is not experiencing various pressure every day all the time; The deterioration of environment, the anxiety of transition and pressure, bad life style and the custom and the bad state of mind, all become the stealthy killer of modern metropolitan cities people health, that increasing people feels is own absent minded, forgetful, irritated, fatiguability, easy ill etc., presents various " sub-health states ".
" sub-health state " is called " inferior health status " again, or claims " the human body third state ", " gray states ", " premorbid state ".Be one group of comprehensive syndrome, show as the unusual diseases of a series of psychosomas such as body, psychology, emotion.Present fatiguability, vigor goes down, respond symptom such as go down.Carry out the normal no obvious ill result of comprehensive physico-chemical examination clinical, or the result is in critical value, but the patient always feels body and psychological discomfort, can have a strong impact on people's quality of life.The World Health Organization (WHO) proposes, the most typical fatigue that shows as of inferior health, and what accompany with fatigue then is psychology and physiological dual discomfort.Mainly show as listless, depressed, slow in reacting, insomnia and dreamful sleep or drowsiness sleepy, absent minded, forgetful, irritated, anxiety, easily frightened etc. psychologically; Nose heave, uncomfortable in chest, the weak burnout of the conscious dizziness of patient, poor appetite, palpitaition, spontaneous perspiration, the miserable pain of articular muscle, sexual dysfunction etc. aspect body.
A global investigation of the World Health Organization shows, only has 5% the people of whole world true health, and checks and also had only 20% by the people that diagnosis suffers from disease that through the doctor all the other people of 75% all are in sub-health state.Other has data to show: there is the 6000000 people sub-health state that is under a cloud every year in the U.S., and the population that is in sub-health state in Australia reaches 3,700 ten thousand.In the area, Asia, the ratio that is in sub-health state is then higher.The research and development of withering of Japan Institute of Public Health are existing, in the thousands of employee who accepts investigation, have 35% people just standing the misery that inferior health brings, and have at least more than half a year the time that continues.Domestic situation also allows of no optimist.Once reported that an investigation of carrying out at 330,000 each personage of stratum in 33 cities of China showed have nearly 70% Chinese to be in sub-health state, then has the people more than 70% to be in sub-health state among high level intellectual and the enterprise and institution management person.
The reason that causes human body sub-health state to occur has multiple, its reveal any symptoms is also varied, but the most important, and the most essential most crucial problem is that the human body self immunologic hypofunction causes, therefore, raising human body immunity of organisms is the most important solution away from inferior health.
There is the custom of drinking tea in China from ancient times, and apart from the modern history that has had several thousand, people usually will drink millet paste as resisting illness, and the indispensable drink that delays senility has stronger immunoregulation effect.Prove that through modern medicine the material that plays immunoregulation effect in the tealeaves mainly is a Tea Polyphenols, it accounts for 18%～36% of stem tea usually.Tea Polyphenols mainly shows as the following aspects to Immune Effects: the existing stimulation facilitation of immunologic function is had partial inhibition again, and based on facilitation, Tea Polyphenols has the dual characteristics of endogenous antioxidant and exogenous antioxidant concurrently, it is regulated by transportation in intracellular effect, rather than simple diffusion, therefore Tea Polyphenols is comparatively complicated to the influence of immunity of organism, is the resultant effect of coordinating mutually; Tea Polyphenols has the promotion of stimulation immunity to improve or the rise effect to immunologic hypofunction, but normal immunologic function is had certain regulating action, promptly nospecific immunity and cellular immunity is had facilitation, and humoral immunity is had inhibitory action, can prevent that immunity is strong excessively; Tea Polyphenols can be by body immune organ (central immune organ thymus gland and peripheral immune organ's spleen etc.), immunocyte (lymphocyte, interleukins, huge have a liking for cell, red blood cell etc.) and immune molecule (immunoglobulin (Ig), complement etc.) play the function of regulating body immune system; In addition, Tea Polyphenols can be by lowering the cell peroxide content or playing the effect of regulating immunity by eliminating the excessive free radicals that generates in the immune response pathway.
Vitamin E has biological action widely as a kind of liposoluble vitamin, and wherein the relation between vitamin E and the immunologic function causes numerous scholars' attention.A large amount of experimental studies show that when TD, the humoral immunity of body, cellular immunity and nospecific immunity all present reduction or inhibition in various degree, and additional an amount of vitamin E can make immunologic function be improved or recover.Along with the progress of immunology and Protocols in Molecular Biology, the immune regulation mechanism of vitamin E complexity there has been new understanding, think closely related at present with its anti peroxidation of lipid characteristic.The structure of vitamin E comprises a chroman ring and a phytol side chain, vitamin E is by particularly arachidonic acid recurring structure reaction of the polyunsaturated fatty acid on its phytol side chain and the film, make its chroman ring be exposed to the film surface, but this ring Mulberry Extract and form fertility semiquinone free radical, and stop the chain reaction that free radical causes lipid peroxidation effectively.Its result is: be the flowability of stabilising membrane on the one hand, the function that cell membrane and organelle film are brought into normal play in process of immune regulation comprises secrete cytokines, surface antigen and receptor expression, lymphocyte transformation and cytolysis etc.; Be regulate PGE2 synthetic on the other hand, influence generation and lymphocytic differentiation, propagation and the activation of interleukins.
Vitamin E is the micro constitutent that itself just contains in the vegetable oil, owing to the more nutritive value of edible oil that makes of loss in vegetable oil processing deodorising process greatly reduces, reasonably replenishing vitamins E is in edible oil, make when taking in edible oil except replenishing fat and essential fatty acid, can also replenish vitamin E in right amount, strengthen the immunocompetence of body.
Edible oil only limits to the mixed collocation of different cultivars vegetable oil at present, is worth and only limits to the adjustment of aliphatic acid or the adjustment of edible oil local flavor, its essence is simply piling up of vegetable oil.But edible vegetable oil will have some the not saponification compounds of nutritive value such as vitamin E and some aldehydes matters in the refining process in processing but greatly partly to be removed, and makes the nutritive value of edible oil greatly reduce.
Summary of the invention
Studies show that vitamin E can strengthen the human immunological competence, Tea Polyphenols has immunoregulation effect, and vitamin E and Tea Polyphenols are taken in simultaneously, because the synergistic function of vitamin E and Tea Polyphenols, its functional characteristic significantly strengthens.Tea Polyphenols is as a kind of source rich in natural resources, and is cheap, adds to simultaneously in the edible oil with vitamin E, has significant immunoregulation effect, for improving health, strengthens immunity of organisms, away from inferior health, has crucial meaning.
The technical problem to be solved in the present invention provides a kind of immune regulation nutrient edible oil, and it can strengthen immunoregulation effect, improves the immunological regulation system of human body.
For solving the problems of the technologies described above, a kind of immune regulation nutrient edible oil of the present invention comprises edible oil, also comprises vitamin E and Tea Polyphenols.
The weight percentage of described Tea Polyphenols is 0.06-0.3%, the weight percentage 0.06-0.162% of vitamin E.
Described edible oil is a sunflower oil.
A kind of preparation method of nutrient edible oil, it may further comprise the steps:
1) batching: the weight percentage of Tea Polyphenols is 0.06-0.3%, the weight percentage 0.06-0.162% of vitamin E, and all the other are edible oil;
1) join in the material-compound tank mixedly, the temperature maintenance of material-compound tank is at 45 ~ 55 ℃;
2), filter, to fill nitrogen canned through static mixer.
Mix at least 30 minutes time of stirring in the described material-compound tank.
The canned oily temperature control of described batching is at 20 ~ 30 ℃.
The invention has the beneficial effects as follows: owing in carrier edible vegetable oil, add Tea Polyphenols and vitamin E.And adopted this preparation method; do not add any artificial antioxidant; and be added in the unsaponifiable matter vitamin E and the aldehydes matter of loss in the edible vegetable oil refining processing; and under the protection of filling nitrogen; improved the nutritive value of edible oil greatly, made this nutrient edible oil have significant immunoregulation effect, after human body is taken in this kind ready-mixed oil; have immunoregulatory effect, can improve the immunological regulation system of human body self.Make people away from inferior health.
The specific embodiment
Embodiment 1
Select sunflower seeds one-level oil 997.00kg for use, Tea Polyphenols 2.10kg, vitamin E 0.90kg, join in the material-compound tank, the temperature maintenance of material-compound tank is at 52 ± 2 ℃, and is mixed through motionless mixer again behind the stirring 30min, the oil temperature is 30 ℃, filter, fill the canned reality of nitrogen and get 999.65kg vegetable oil ready-mixed oil finished product, the finished product yield is 99.97%.
Annotate: the vitamin E that contains 40mg in every 100g sunflower oil
Embodiment 2
Select sunflower seeds one-level oil 998.15kg for use, Tea Polyphenols 0.65kg, vitamin e1 .20kg, join in the material-compound tank, the temperature maintenance of material-compound tank is at 49 ± 2 ℃, and is mixed through motionless mixer again behind the stirring 30min, the oil temperature is 25 ℃, filter, fill the canned reality of nitrogen and get 999.82kg vegetable oil ready-mixed oil finished product, the finished product yield is 99.98%.
Embodiment 3
Select sunflower seeds one-level oil 997.45kg for use, Tea Polyphenols 1.45kg, vitamin e1 .10kg, join in the material-compound tank, the temperature maintenance of material-compound tank is at 47 ± 2 ℃, and is mixed through motionless mixer again behind the stirring 30min, the oil temperature is 24 ℃, filter, fill the canned reality of nitrogen and get 999.79kg vegetable oil ready-mixed oil finished product, the finished product yield is 99.98%.
Embodiment 4
Select sunflower seeds one-level oil 996.85kg for use, Tea Polyphenols 2.85kg, vitamin E 0.30kg, join in the material-compound tank, the temperature maintenance of material-compound tank is at 53 ± 2 ℃, and is mixed through motionless mixer again behind the stirring 30min, the oil temperature is 29 ℃, filter, fill the canned reality of nitrogen and get 999.56kg vegetable oil ready-mixed oil finished product, the finished product yield is 99.96%.
Embodiment 5
Select sunflower seeds one-level oil 996.85kg for use, Tea Polyphenols 2.95kg, vitamin E 0.20kg, join in the material-compound tank, the temperature maintenance of material-compound tank is at 53 ± 2 ℃, and is mixed through motionless mixer again behind the stirring 30min, the oil temperature is 30 ℃, filter, fill the canned reality of nitrogen and get 999.91kg vegetable oil ready-mixed oil finished product, the finished product yield is 99.99%.
Embodiment 6
Select sunflower seeds one-level oil 997.95kg for use, Tea Polyphenols 1.60kg, vitamin E 0.45kg, join in the material-compound tank, the temperature maintenance of material-compound tank is at 48 ± 2 ℃, and is mixed through motionless mixer again behind the stirring 30min, the oil temperature is 21 ℃, filter, fill the canned reality of nitrogen and get 999.68kg vegetable oil ready-mixed oil finished product, the finished product yield is 99.97%.
Embodiment 7
Select sunflower seeds one-level oil 998.45kg for use, Tea Polyphenols 0.85kg, vitamin E 0.70kg, join in the material-compound tank, the temperature maintenance of material-compound tank is at 47 ± 2 ℃, and is mixed through motionless mixer again behind the stirring 30min, the oil temperature is 20 ℃, filter, fill the canned reality of nitrogen and get 999.86kg vegetable oil ready-mixed oil finished product, the finished product yield is 99.99%.
Embodiment 8
Select sunflower seeds one-level oil 998.40kg for use, Tea Polyphenols 1.00kg, vitamin E 0.60kg, join in the material-compound tank, the temperature maintenance of material-compound tank is at 52 ± 2 ℃, and is mixed through motionless mixer again behind the stirring 30min, the oil temperature is 28 ℃, filter, fill the canned reality of nitrogen and get 999.76kg vegetable oil ready-mixed oil finished product, the finished product yield is 99.98%.
More than the content such as the following table 1 of Tea Polyphenols, vitamin E in each embodiment gained nutrient edible oil.
The content of Tea Polyphenols and vitamin E in the different case study on implementation of table 1.
As can be seen from Table 1, in the nutrient edible oil of each embodiment, the every 100g of the content of Tea Polyphenols is 60mg-300mg, and the content of vitamin E is that every 100g is 60mg-162mg.
At Fudan University's food toxicity and the health food Function detection center of Ministry of Public Health's appointment, carry out the immunologic function evaluation with assessment technique standard pertinent regulations with example 1 prescription according to the health food check:
Body weight
See Table 2, table 3, each treated animal is at the body weight difference not statistically significant of duration of test.
The body weight of table 2. animal (g, median ± difference)
Thymus gland/body weight of table 3. animal and spleen/body weight ratio sees Table 3
The mouse spleen lymphocyte transformation experiment
As shown in Table 4, its OD value was higher than control group with the difference that does not add the OD value of ConA after high dose group added ConA, and difference has statistical significance (P＜0.01).
Table 4. mouse spleen lymphocyte transformation experiment result
**P＜0.01
Dinitrofluorobenzene inducing mouse DTH experimental result
As shown in Table 5, the difference of left and right sides ear weight does not have statistical significance between each group.
Table 5.DTH bears results
Humoral immune function
As shown in Table 6, high dose group animal's antibody level is higher than control group, and analyzing by statistics has significant difference (P＜0.01).
Table 6. humoral immune function testing result
* compares with low dose group with control group, P＜0.01; * compare with control group, P＜0.05 monokaryon-huge has a liking for cell function
Mouse carbon is cleaned up experiment
Table 7. mouse carbon is cleaned up experimental result
Mouse peritoneal is huge has a liking for the experiment of cell diagram chicken red blood cell
Table 8. mouse peritoneal is huge has a liking for cell diagram chicken red blood cell experimental result
* compares with low dose group with control group, P＜0.01; A: compare P＜0.05 with low dose group; B: compare P＜0.01 with low dose group
The NK cytoactive
Table 9.NK cytoactive
ConA is meant concanavalin A; DTH is meant delayed allergy; P is meant the significance in the mathematical statistics;
By above experiment as can be seen:
The mouse spleen lymphocyte transformation experiment is the result show, its OD value was higher than control group with the difference that does not add the OD value of ConA after high dose group added ConA, and difference has statistical significance (P＜0.01); The serum hemolysin testing result shows that middle and high dosage treated animal antibody horizontal is higher than control group, and there were significant differences (P＜0.05, P＜0.01) in analysis by statistics; Mouse peritoneal is huge to be had a liking for cytophagy chicken red blood cell experimental result and shows, the phagocytic percentage of each dosage treated animal (%) and transform phagocytic percentage (%) and be higher than control group (P＜0.01); The phagocytic index of middle and high dosage treated animal is higher than control group (P＜0.01), according to the evaluation criterion of health food check with assessment technique standard pertinent regulations, can think that this is tried thing and has the effect of the immunity function of enhancing.
By functional evaluation as can be known, nutrient edible oil of the present invention has immunoregulation effect.
Claims (6)
1. an immune regulation nutrient edible oil comprises edible oil, it is characterized in that: also comprise vitamin E and Tea Polyphenols.
2. according to right 1 described immune regulation nutrient edible oil, it is characterized in that: the weight percentage of Tea Polyphenols is 0.06-0.3%, the weight percentage 0.06-0.162% of vitamin E.
3. according to right 1 or 2 described immune regulation nutrient edible oils, it is characterized in that: described edible oil is a sunflower oil.
4. the preparation method of an immune regulation nutrient edible oil is characterized in that may further comprise the steps:
1) batching: the weight percentage of Tea Polyphenols is 0.06-0.3%, the weight percentage 0.06-0.162% of vitamin E, and all the other are edible oil;
2) join in the material-compound tank mixedly, the temperature maintenance of material-compound tank is at 45 ~ 55 ℃;
3), filter, to fill nitrogen canned through static mixer.
5. the preparation method of immune regulation nutrient edible oil according to claim 4 is characterized in that: step 2) in time of mix stirring be at least 30 minutes.
6. according to the preparation method of claim 4 or 5 described immune regulation nutrient edible oils, it is characterized in that: the canned oily temperature control of step 3) is at 20 ~ 30 ℃.
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| CNA2007100406640A CN101305753A (en) | 2007-05-15 | 2007-05-15 | Immune regulation nutrient edible oil and its preparation method |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103815058A (en) * | 2014-03-06 | 2014-05-28 | 洛阳春魁农业开发有限公司 | Blend edible oil of peony seed oil and rice germ oil and preparation method of blend edible oil |
| CN103815059A (en) * | 2014-03-06 | 2014-05-28 | 洛阳春魁农业开发有限公司 | Blend oil containing peony seed oil and preparation method thereof |
| CN105309635A (en) * | 2014-07-11 | 2016-02-10 | 马井芳 | Healthcare edible oil containing tea polyphenol and preparation method thereof |
-
2007
- 2007-05-15 CN CNA2007100406640A patent/CN101305753A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103815058A (en) * | 2014-03-06 | 2014-05-28 | 洛阳春魁农业开发有限公司 | Blend edible oil of peony seed oil and rice germ oil and preparation method of blend edible oil |
| CN103815059A (en) * | 2014-03-06 | 2014-05-28 | 洛阳春魁农业开发有限公司 | Blend oil containing peony seed oil and preparation method thereof |
| CN103815058B (en) * | 2014-03-06 | 2015-06-17 | 洛阳春魁农业开发有限公司 | Blend edible oil of peony seed oil and rice germ oil and preparation method of blend edible oil |
| CN105309635A (en) * | 2014-07-11 | 2016-02-10 | 马井芳 | Healthcare edible oil containing tea polyphenol and preparation method thereof |
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Open date: 20081119 |