CN101302528B - 参与螺旋霉素生物合成的多肽、编码这些多肽的核苷酸序列及其应用 - Google Patents

参与螺旋霉素生物合成的多肽、编码这些多肽的核苷酸序列及其应用 Download PDF

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CN101302528B
CN101302528B CN2008100823963A CN200810082396A CN101302528B CN 101302528 B CN101302528 B CN 101302528B CN 2008100823963 A CN2008100823963 A CN 2008100823963A CN 200810082396 A CN200810082396 A CN 200810082396A CN 101302528 B CN101302528 B CN 101302528B
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China
Prior art keywords
gene
sequence
spiramycin
protein
polypeptide
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Expired - Lifetime
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CN2008100823963A
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English (en)
Chinese (zh)
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CN101302528A (zh
Inventor
M-H·布隆德莱-鲁奥
H·多明格斯
E·达尔邦-龙热尔
C·热尔博
A·贡德朗
F·卡拉伊
P·拉克鲁瓦
N·厄斯特赖歇尔-梅尔梅-布维耶
J-L·佩尔诺代
K·蒂皮海尔
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Centre National de la Recherche Scientifique CNRS
Aventis Pharma SA
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Centre National de la Recherche Scientifique CNRS
Aventis Pharma SA
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Priority claimed from FR0302439A external-priority patent/FR2851773A1/fr
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN2008100823963A 2002-10-08 2003-10-08 参与螺旋霉素生物合成的多肽、编码这些多肽的核苷酸序列及其应用 Expired - Lifetime CN101302528B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR0212489A FR2845394A1 (fr) 2002-10-08 2002-10-08 Polypeptides impliques dans la biosynthese des spiramycines, sequences nucleotidiques codant ces polypeptides et leurs applications
FR0212489 2002-10-08
FR0302439 2003-02-27
FR0302439A FR2851773A1 (fr) 2003-02-27 2003-02-27 Polypeptides impliques dans la biosynthese des spiramycines, sequences nucleotidiques codant ces polypeptides et leurs applications

Related Parent Applications (1)

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CNA2003801029666A Division CN1711355A (zh) 2002-10-08 2003-10-08 参与螺旋霉素生物合成的多肽、编码这些多肽的核苷酸序列及其应用

Publications (2)

Publication Number Publication Date
CN101302528A CN101302528A (zh) 2008-11-12
CN101302528B true CN101302528B (zh) 2012-05-30

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CN2008100823963A Expired - Lifetime CN101302528B (zh) 2002-10-08 2003-10-08 参与螺旋霉素生物合成的多肽、编码这些多肽的核苷酸序列及其应用
CNA2003801029666A Pending CN1711355A (zh) 2002-10-08 2003-10-08 参与螺旋霉素生物合成的多肽、编码这些多肽的核苷酸序列及其应用

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Application Number Title Priority Date Filing Date
CNA2003801029666A Pending CN1711355A (zh) 2002-10-08 2003-10-08 参与螺旋霉素生物合成的多肽、编码这些多肽的核苷酸序列及其应用

Country Status (3)

Country Link
CN (2) CN101302528B (fr)
FR (1) FR2845394A1 (fr)
ZA (1) ZA200502139B (fr)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0791655A2 (fr) * 1996-02-22 1997-08-27 Eli Lilly And Company Gènes de polyketide-synthase
EP0791656A3 (fr) * 1996-02-22 2000-10-18 Eli Lilly And Company Gène de la platenolide-synthase

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001511349A (ja) * 1997-07-25 2001-08-14 ヘキスト・マリオン・ルセル Ｓａｃｃｈａｒｏｐｏｌｙｓｐｏｒａｅｒｙｔｈｒａｅａ及びＳｔｒｅｐｔｏｍｙｃｅｓａｎｔｉｂｉｏｔｉｃｕｓにおける６−デオキシヘキソースの生合成及び移送のための遺伝子

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0791655A2 (fr) * 1996-02-22 1997-08-27 Eli Lilly And Company Gènes de polyketide-synthase
EP0791656A3 (fr) * 1996-02-22 2000-10-18 Eli Lilly And Company Gène de la platenolide-synthase

Also Published As

Publication number Publication date
ZA200502139B (en) 2006-05-31
CN101302528A (zh) 2008-11-12
FR2845394A1 (fr) 2004-04-09
CN1711355A (zh) 2005-12-21

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