CN101283675A - Positive/passive exercise training device for simulating weightless tail suspended rats - Google Patents
Positive/passive exercise training device for simulating weightless tail suspended rats Download PDFInfo
- Publication number
- CN101283675A CN101283675A CNA200810114305XA CN200810114305A CN101283675A CN 101283675 A CN101283675 A CN 101283675A CN A200810114305X A CNA200810114305X A CN A200810114305XA CN 200810114305 A CN200810114305 A CN 200810114305A CN 101283675 A CN101283675 A CN 101283675A
- Authority
- CN
- China
- Prior art keywords
- rat
- tail
- fixed
- suspended
- training device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Abstract
The invention provides a tail-suspended rat fixing device which comprises a tail suspension device, a rat fixing box for storing the head and body of a rat, a body fixing device for fixing the body of a rat, an angle control device for controlling the included angle between the rat fixing box and a pedestal of the tail-suspended rat fixing device. The invention also provides a tail-suspended rat active/passive motion training device which comprises a rat hind limb motion device for training active/passive motion of the hind limb of a rat and further comprises a motion orbit control device for limiting the motion range of the hind limb of a rat, an active motion training device for training the active motion of the hind limb of a rat, and a passive motion training device for training the passive motion of the hind limb of a rat. The invention realizes the motion training and simultaneously keeps the tail suspension angle unchanged, that is, keeps the rat in a simulated weightlessness state.
Description
Technical field
The present invention relates to space flight biomedical engineering research field, more particularly relate to a kind of can be under simulated weightlessness conditions tail-suspended rat being led/device of continuous passive motion.
Background technology
The astronaut enters space, and serious weightlessness bone loss can take place, load-bearing bone bone amount was lost 1.0-1.6% in average every month, the highlyest can reach 13.6%, mass loss rates annual bone loss rate (3%) behind the postmenopausal women, this will directly influence spacefarer's health and ability to work.Zooperal data show that training is a kind of measure that resists weightlessness bone loss safely and effectively.Because the finiteness of space test, the data of this respect mainly is to obtain by the weightless model of ground simulation at present.
NASA (NASA) in last century middle nineteen seventies set up and developed can be at the animal model of ground simulation space biological effect---the rat tail hangs model, by the afterbody suspention rat hindlimb being removed bears a heavy burden, and forelimb still keeps bearing a heavy burden, thereby simulate hind leg weightlessness bone loss effect, now be widely used in the research of the mechanism and the counter measure of weightlessness bone loss.
Utilizing the mouse tail to hang in the Study of model, used training has intermittent level to stand and head height position (the Cao new life etc. that stand, stand to the influence of simulated weightlessness rat femur mechanical characteristic in discontinuity level position, Chinese Journal of Aerospace Med, 2000,11 (3): 170-173. Cao new life etc., 45 ° of head height positions of discontinuity are to the influence of tail-suspended rat femur biomechanics characteristic, Space Medicine; MedicalEngineering, 2000,13 (5): 328-331.), (Hauschka et al. runs, Periodic weightsupport effects on rat soleus fibers after hindlimb suspension.the AmericanPhysiological Society.1988,0161-7567/88.Ishihara et al., Effects of runningexercise during recovery from hindlimb unloading on soleus muscle fibers and theirspinal motoneurons in rats.Neuroscience Research, 2004,48:119-127.).But these trainings can not be carried out keeping tail to hang under the state always.Have plenty of that convalescence after tail hangs carries out.
Fluckey etc. design a kind of rat tail and hang the resistive exercise device, and can making rat can be in tail, to hang state be that simulated weightlessness carries out resistive exercise.Motion mode is similar to human " yo-yo " motion, is to utilize flying wheel to drive rat to do the motion that stoops.But there is a series of problem in its design, for example: in motion process, can not remain same tail and hang angle, motion exercise is not to carry out at hind leg, the load of hind leg can't quantitatively wait, and difficulty is provided with corresponding control group (J.D.Fluckey etal., A rat resistance exercise regimen attenuates losses of musculoskeletal massduring hindlimb suspension.Acta Physiol Scand, 2002,176:293-300.).
Therefore, pressing in this field provides a kind of and can keep same tail hang under the simulated weightlessness of angle, and rat is led/trainer of passive controlled, quantitative exercise training.
Summary of the invention
Hang in order to overcome present rat tail that the rat tail that exists in the trainer hangs that angle can not keep, rat master passive exercise can not Quantitative Monitoring, the problem of control, the invention provides a kind of can hanging under the simulated weightlessness of angle at the same tail of maintenance, rat is led/trainer of passive controlled, quantitative exercise training, be used to study and seek and optimize the effective exercise method that antagonism weightlessness sclerotin is lost.
According to an aspect of the present invention, provide a kind of tail-suspended rat positioner, be used to carry out the weightless flight test, it is characterized in that comprising: the tail device for hoisting is used to suspend in midair rat tails; Big mouse fixed case is used to hold head and the torso portion of rat; Angle controller is used to control the angle between the base of described big mouse fixed case and described tail-suspended rat positioner, thus trunk of control rat and the angle between the described base.
Preferably, in described tail-suspended rat positioner, the end opening that described big mouse fixed case is higher, and its lower end is provided with the rat apparatus for adjusting position, is used for changing the position of rat at big mouse fixed case.
According to one embodiment of the present invention, in described tail-suspended rat positioner, described angle controller comprises a holder, and this holder comprises: the holder chassis, and it is fixed on the described base; The holder support, it is fixed on the described holder chassis and which is provided with a rat trunk and passes through the hole; And the below of a higher end of described big mouse fixed case is provided with hook, and this hook is used to make described big mouse fixed case and described holder support to be connected and fixed.
According to another embodiment of the invention, in described tail-suspended rat positioner, described angle controller comprises: an angle control panel, it is set near the lower end of described big mouse fixed case, its lower end is fixed on the described base, be provided with fixture at its differing heights, be used for a lower end, to regulate the height of a described lower end with respect to described base at the fixing described big mouse fixed case of differing heights; One bearing arrangement, it is fixed on the described base, and described big mouse fixed case is fixed on the described bearing arrangement rotationally with respect to described base.
According to another aspect of the present invention, a kind of tail-suspended rat master/passive exercise training device is provided, be used for rat is carried out master/continuous passive motion under the simulated weightlessness, it is characterized in that comprising: the rat hindlimb telecontrol equipment: be used for the hind leg of rat is carried out active or continuous passive motion, it further comprises: the TRAJECTORY CONTROL device: the range of movement that is used to limit rat hindlimb; Active movement trainer: be used for rat hindlimb is carried out the active movement training; And passive exercise training device: be used for rat hindlimb is carried out continuous passive motion.
Preferably, in described tail-suspended rat master/passive exercise training device, described TRAJECTORY CONTROL device comprises: the movement locus confinement plate; Bearing arrangement, it is fixed on the base of described motion training device, and described movement locus confinement plate is to be connected on the described bearing arrangement with respect to the rotating mode of described base; The load regulation rubber band, the one end is fixed with respect to described base, and the other end is fixed on the end of described movement locus confinement plate near rat; The first sports limiting bar, it is set at the end of described bearing arrangement near rat; The second sports limiting bar, it is set at the end of described bearing arrangement away from rat.
Preferably, in described tail-suspended rat master/passive exercise training device, the lower end of the described first sports limiting bar is fixed on the described base, and its upper end is provided with a damping cap, changes the height of the described first sports limiting bar with the rotation by described damping cap; The lower end of the described second sports limiting bar is fixed on the described base, and its upper end is provided with a damping cap, changes the height of the described second sports limiting bar with the rotation by described damping cap.
Preferably, in described tail-suspended rat master/passive exercise training device, described master/passive exercise training device further comprises a pair of pedal, and it is set at described movement locus confinement plate near the end of rat, is used for placing respectively and the fixing a pair of hind leg of rat; Described active movement trainer comprises: egersimeter, and its electrode tip is connected on the described pedal, is used to give the electro photoluminescence of rat vola; Single-chip microcomputer is used to control the electro photoluminescence number of times of described egersimeter.
Preferably, in described tail-suspended rat master/passive exercise training device, described passive exercise training device comprises: motor: be fixed on the described base; Backguy: the one end is fixed on the turning cylinder of described motor, and the other end is fixed on the backguy connecting hole of described movement locus confinement plate, and described backguy connecting hole is arranged at the end away from rat of described movement locus confinement plate.
Preferably, in described tail-suspended rat master/passive exercise training device, further comprise foregoing tail-suspended rat positioner.
The present invention has compared following beneficial effect with existing rat motor device:
The present invention has designed big mouse fixed case, utilize the habit of getting into the cave of rat, rat can be pierced head and body in the fixed bin, hind leg exposes, fixed bin is provided with angle controller, make the trunk of rat and the base of described motion training device keep certain angle, and the afterbody of rat is fixed on the tail device for hoisting, make rat remain a tail of low level certain angle and hang state.The rat body posture is stable in the experimentation, the experimenter is not threatened, and got rid of the interference of other limb motions of rat to experiment.
The present invention has also designed rat hindlimb motion assembly, utilizes screw to be fixed on the base, and its structure is similar to seesaw, and the rat foot is fixed on the rat hindlimb motion assembly of seesaw one end with medical proof fabric.Do initiatively motion for making rat, utilize egersimeter that height is forced down the pulsed arc spread effect of stream in the rat vola from design, rat can initiatively shrink hind leg to hide the pain that electric shock is produced, the contraction of rat hindlimb need overcome quantitative load in this process, thereby reaches the purpose that rat hindlimb is done the resistive drag force active movement.Movement load and the movement locus of load rubber band and track restraint device control rat, the amount of exercise of the number of times control rat of electro photoluminescence.For making rat do passive movement, then need use the end of the drop-down seesaw of driven by motor connecting line away from mouse, pulling force overcomes load and drives the rat hindlimb contraction, does allokinetic purpose thereby reach rat hindlimb.Allokinetic movement locus is controlled by the track restraint device equally, and amount of exercise is by the drop-down number of times decision of motor.
This shows that the present invention can realize the resistive drag force active movement at the tail-suspended rat hind leg; When can be implemented in training, the rat tail hangs angle and remains unchanged, and promptly remains simulated weightlessness; Can realize the control to rat master/passive exercise, carry out quantification training, guarantee the track unanimities of two groups of motions, and control group moves except hind leg, other conditions and exercise group are in full accord.
Description of drawings
Fig. 1 is the structural map of active/passive exercise training device for simulated weightless tail-suspended rat according to an embodiment of the invention.
Fig. 2 is the structural map of holder according to an embodiment of the invention.
Fig. 3 A is the structural map of the big mouse fixed case of fixed angle according to an embodiment of the invention.
Fig. 3 B is the structural map that adjustable angle according to an embodiment of the invention saves big mouse fixed case.
Fig. 4 is the structural map of rat hindlimb resistive exercise device according to an embodiment of the invention.
Fig. 5 is the structural map of adjustable angle active movement device according to an embodiment of the invention.
Embodiment
In Fig. 1, comprise base 101, tail hanging beam 102, holder 103, big mouse fixed case 104, rat left hind resistive exercise device 105, right hind resistive exercise device 106, tail hanging beam support 107, tail suspension ring 108, and 6 base supports 109.
Wherein said tail hanging beam 102 is fixed on the tail hanging beam support 107, and tail hanging beam support 107 is connected with screw fixation method or other conventional fixed forms with base 101, thereby makes tail hanging beam 102 be fixed on the base 101; Tail suspension ring 108 are arranged on tail hanging beam 102, be used to suspend in midair rat tails.
Wherein said holder 103 places on the base 101, is used to support big mouse fixed case 104.The position of holder 103 on base 101 is adjustable, thereby guarantee rat hindlimb with different length place left right hind resistive exercise device 105 on 106, the method for holder 103 usefulness such as the screw lock of adjusting is fixed on the base 101.
In embodiment as shown in Figure 1, big mouse fixed case 104 is connected with holder 103 removably by hook 303, is used for placement and fixing rat.Big mouse fixed case 104 is fixed with respect to the position of holder 103, make that angle remains 30 ° between it and the base 101, thereby the tail that makes rat all keep 30 ° of low levels in whole sport training process hangs state.
It should be noted that in the embodiment shown in Fig. 1-3 holder 103 constitutes an integral body with rat hindlimb holder 203, but this is not to realize sole mode of the present invention; As the optional embodiment of another kind, also can constitute an integral body to rat hindlimb holder 203 and big mouse fixed case 104, and this integral installation is fitted on the holder 103 that does not comprise rat hindlimb holder 203.In this embodiment, limit the part of rat trunk by hole 204 and can be included in the integral body that rat hindlimb holder 203 and big mouse fixed case 104 constitute, rather than as the part of holder 103.Angle can be 0-80 ° of variation between described big mouse fixed case 104 and the base 101, thereby a low level tail that makes rat all keep different angles in whole sport training process hangs state, these angles and are not limited only to 30 ° all within interest field of the present invention.Wherein holder 104 and fixed bin 103 can adopt split type design (as shown in Figure 3A), also the two can be combined, become adjustable angle and save big mouse fixed case (shown in Fig. 3 B), split type structure can accurately be located angle, and conveniently rat is controlled, and the structure of combination type can be regulated angle.
Rat left hind resistive exercise device 105, right hind resistive exercise device 106 are connected on the base 101 with screw fixation method or other conventional fixed forms, the two structure is a symmetric relation, being used for that rat hindlimb is applied main/passive resistive exercise trains, and can use separately.
Fig. 2 has shown an embodiment according to holder 103 of the present invention.As shown in Figure 2, holder 103 comprises holder chassis 201, holder support 202, rat hindlimb holder 203.Holder support 202 is fixed on the holder chassis 201, a rat trunk is arranged by hole 204 on holder support 202, is used for fixing the rat trunk; Rat hindlimb holder 203 is fixed on the rat trunk of holder support 202 1 sides by 204 belows, hole, is used for fixing rat hindlimb.Two rat hindlimbs are arranged by hole 205 and shape of a saddle projection 206 on rat hindlimb holder 203, and rat hindlimb holder 203 whole with chassis 201 between angle and greatly between mouse fixed case 104 and the base 101 angle be consistent.
As a kind of embodiment, the material of holder 103 is lucite, adopts chloroform bonding.
In the embodiment shown in Fig. 3 A, big mouse fixed case 104 comprises that the rat position adjustments takes over a business 301, rat position adjustments bolt 302, hook 303.At an end opening of big mouse fixed case 104, be connected on the holder support 202 of holder shown in Figure 2 103 by the hook 303 below the openend, make big mouse fixed case 104 be communicated with by hole 204 with the rat trunk; The other end at big mouse fixed case has a rat position adjustments that links to each other with rat position adjustments bolt 302 to take over a business 301, when rotating rat position adjustments bolt 302, the rat position adjustments is taken over a business 301 positions in big mouse fixed case 104 and can be changed thereupon, thereby change the position of rat in big mouse fixed case 104, be placed on the pedal 401 of rat left side right hind resistive exercise device 105 106 after by hole 205 thereby make the rat foot pass rat hindlimb.
As previously mentioned, can the two combine with holder 104 and fixed bin 103, become adjustable angle and save big mouse fixed case, Fig. 3 B has shown that adjustable angle saves an embodiment of big mouse fixed case.Shown in Fig. 3 B, big mouse fixed case 104 is provided with that the rat position adjustments takes over a business 301, rat position adjustments bolt 302, angle control panel 304, vertically restraining 306, hind leg brace summer 307, transverse beam ligature 308.Other establishes a bearing arrangement 305, it is fixed on the base 101, the upper end is cut, big mouse fixed case 104 is fixed on the section of bearing arrangement 305 upper ends by connected mode such as bonding, and promptly big mouse fixed case 104 is fixed on the described bearing arrangement 305 (referring to Fig. 5) rotationally with respect to base 101.Can be with big mouse fixed case 104 other end relative with openend, be that the lower end of big mouse fixed case 104 is fixed on the differing heights on the angle control panel 304, realization is to the adjusting of big mouse fixed case 104 with respect to base 101 angles, its implementation can be the punching of the differing heights on angle control panel 304, fix a lower end of big mouse fixed case 104 at differing heights to utilize band to pass described hole, perhaps the differing heights on angle control panel 304 is provided with locating slot, lower end with fixing big mouse fixed case 104 can also adopt other feasible mode to realize certainly.Vertically restraining 306, hind leg brace summer 307 and transverse beam ligature 308 have been finished the function of holder 103, can fix rat.
Fig. 4 is rat hindlimb resistive exercise device construction figure according to an embodiment of the invention.In the embodiment shown in fig. 4, the structure of rat left hind resistive exercise device 105 and right hind resistive exercise device 106 is identical, comprises TRAJECTORY CONTROL device, active movement trainer and passive exercise training device; Their symmetric arrays on base 101, be respectively rat left right hind provide main the training of passive resistive exercise.
The TRAJECTORY CONTROL device comprises pedal 401, hinge 402, load rubber band 403, original state adjusting rod 404, damping cap 405, bearing arrangement 406, movement locus confinement plate 407 and rat motor limit rod 408.Wherein pedal 401 is set at rat hindlimb holder 203 belows of holder 103, and being connected movement locus confinement plate 407 1 ends by hinge 402, pedal 401 is used for placing and fixing rat left and right sides hind leg (can tie up rat hindlimb at pedal 401 with medical adhesive tape or elastic cord); Bearing arrangement 406 lower ends are fixed on the base 101, bearing arrangement 406 upper ends and movement locus confinement plate 407 middle parts connect bonding, the variation of movement locus confinement plate 407 two ends stress balances causes the rotation of bearing arrangement 406, thereby the elevating movement that makes movement locus confinement plate 407 produce similar seesaw has further changed the movement locus that is fixed on the rat hindlimb on the pedal 401; End at the close holder support 202 of bearing arrangement 406 has an original state adjusting rod 404, the lower end of original state adjusting rod 404 is fixed on the base 101, on its upper end a damping cap 405 is arranged, the two connects with screw fashion, can change the height of adjusting rod 404 by mode with spiral rotation rotating oscillation damping cap 405, thus a boundary of the range of movement of adjustment movement track confinement plate 407; The end away from holder support 202 at bearing arrangement 406 has a rat motor limit rod 408, the lower end of rat motor limit rod 408 is fixed on the base 101, on its upper end a damping cap 405 is arranged, the two connects with screw fashion, by can changing the height of rat motor limit rod 408 in modes such as spiral rotation rotating oscillation damping caps 405, thus another boundary of the range of movement of controlled motion track confinement plate 407.
The active movement trainer comprises load rubber band 403 and egersimeter 414.Wherein an end of load rubber band 403 is fixed on the support of bearing arrangement 406, the other end is fixed on the end that movement locus confinement plate 407 links to each other with pedal 401, load rubber band 403 is used to regulate the load of rat hindlimb motion, controls the payload of rat hindlimb motion by the elasticity that changes load rubber band 403.As a kind of embodiment of rat motor behavior command device, adopted an egersimeter 414, its electrode tip is connected on the pedal 401, is used to give the electro photoluminescence of rat vola.Certainly, rat motor behavior command device also can adopt other known solutions, as visual instructions scheme (the J.D.Fluckey et al. that announces in the above-mentioned Fluckey document, Arat resistance exercise regimen attenuates losses of musculoskeletal mass duringhindlimb suspension.Acta Physiol Scand, 2002,176:293 300.), and any other scheme well known in the prior art.
When the rat vola is subjected to being connected in height that pedal 401 top electrodes discharge and forces down the electric arc impulse stimulation of stream, rat can initiatively shrink hind leg to hide the pain that click is produced, thereby an end of movement locus confinement plate 407 is lifted, in this process, need overcome the resistance of load rubber band 403, raising height is by rat motor limit rod 408 decision, initiatively shrinks hind leg and resists certain resistance (or non-resistance) and carry out the initiatively training of resistive exercise thereby finish rat.Wherein,, control the amount of exercise of rat by the number of times of Single-chip Controlling electro photoluminescence by the movement locus of track restraint device control rat by the movement load of load rubber band 403 control rats.
As shown in Figure 4, passive exercise training device comprises backguy 409, backguy connecting hole 410, fixed pulley 411, motor rotation axis 412, motor 413.Wherein motor 413 is fixed on the base 101, one end of backguy 409 is fixed on the turning cylinder 412 of motor 413, the other end passes on the backguy connecting hole 410 that fixed pulley 411 is fixed on movement locus confinement plate 407, motor 413 drives turning cylinder 412 and rotates, twine or loosen backguy 409, thereby drive movement locus confinement plate 407 moves up and down away from the end of mouse, further drives the rat lower limb and does contraction or stretching routine, finishes the continuous passive motion to rat left and right sides hind leg.
Can utilize manual method to twine or loosen backguy 409, move up and down away from the end of mouse, further drive the rat lower limb and do and shrink or stretching routine, finish continuous passive motion rat left and right sides hind leg thereby drive movement locus confinement plate 407.
The allokinetic amount of exercise of FREQUENCY CONTROL that moves downward away from the end of mouse by controlled motion track confinement plate 407.
Embodiment 1 below-G conditions keeps same training angle down
Earlier big mouse fixed case 104 is taken off during use, mention rat tails, near rat head, utilize the habit of getting into the cave of rat to allow rat pierce in the big mouse fixed case 104 opening of big mouse fixed case 104, afterwards big mouse fixed case 104 is utilized hook 303 to be connected with holder 103.Regulate the length that rat position adjustments bolt 302 gos deep in the big mouse fixed case 104,, make rat hindlimb can pass rat hindlimb by hole 205 in conjunction with regulating the position of holder 103 on base 101.Rat tails is suspended on the tail suspension ring 108 again, the rat foot is fixed on a rat left side/right hind resistive exercise device 105/106 with medical proof fabric, and (both are symmetrical structure, can select to adopt one or both sides to train simultaneously as required, be example explanation hereinafter with left side 105) pedal 401 on, can lead hind leg/passive exercise.Because angle is always same angle between big mouse fixed case 104 and the base 101, for example 30 °, so rat all keeps the tail of 30 ° of low levels to hang state in whole sport training process.
Embodiment 2 only trains hind leg
No matter be control group or master/passive exercise group, the whole limbs of rat all are fixed in except that hind leg in the big mouse fixed case 104, its motion is restricted, and the master/continuous passive motion that applies only carries out at hind leg, has got rid of the interference of other limb motions of rat to experiment effectively.
Embodiment 3 adjustable angle are initiatively trained
If backguy 409 is not connected on the junction 410, and big mouse fixed case is when adopting the combination type design, and device as shown in Figure 5.Can only carry out the active movement training, and the angle that the rat tail hangs can be regulated to rat hindlimb.When the rat vola is subjected to being connected in height that pedal 401 top electrodes discharge and forces down the electric arc impulse stimulation of stream, rat can initiatively shrink hind leg to hide the pain that click is produced, thereby an end of movement locus confinement plate 407 is lifted, in this process, need overcome the resistance of load rubber band 403, raising height is by rat motor limit rod 408 decision, initiatively shrinks hind leg and resists certain resistance (or non-resistance) and carry out the initiatively training of resistive exercise thereby finish rat.Wherein,, control the amount of exercise of rat by the number of times of electric stimulating instrument control electro photoluminescence by the movement locus of track restraint device control rat by the movement load of load rubber band 403 control rats.A lamp is set in the rat viewing area, and electric stimulating instrument is controlled this lamp there being when stimulation to light, and sends the sound of " serge " simultaneously.In formal experiment, utilize the conditioned reflex of rat, stimulate instrument meeting elder generation's bright lamp of control and send the sound, if rat hindlimb does not have contraction in 3 seconds, just apply stimulation.Can farthest reduce the interference of electric current like this to experiment.
Embodiment 4 passive exercises
Can utilize manual method, also can utilize motor 413 to drive backguy spool 412 rotates, thereby twine backguy 409, movement locus confinement plate 407 is moved downward away from the end of mouse, drive the passive contraction of rat hindlimb, when motor 413 backward rotation, loosen backguy 409, movement locus confinement plate 407 can be subjected to the pulling force of load rubber band 403 and move downward the passive stretching, extension of drive rat hindlimb, the purpose that this process moves in circles and rat carried out passive exercise to reach near the end of mouse.
Embodiment 5 quantitative trainings
Rat hindlimb master/allokinetic movement locus is all controlled by the height of regulating original state adjusting rod 404 and rat motor limit rod 408; During active movement, select for use the different load rubber band 403 of pulling force as the motion load, can control the size of rat hindlimb motion load, the Single-chip Controlling egersimeter gives the electro photoluminescence of rat vola different frequency, can control the amount of exercise of rat; Allokinetic amount of exercise is then controlled away from the frequency that the end of mouse moves downward by movement locus confinement plate 407.
Claims (10)
1. a tail-suspended rat positioner is used to carry out the weightless flight test, it is characterized in that comprising:
Tail device for hoisting (102,107,108) is used to suspend in midair rat tails;
Big mouse fixed case (104,203) is used to hold head and the torso portion of rat;
Angle controller (103,305,304) is used to control the angle between the base (101) of described big mouse fixed case (104) and described tail-suspended rat positioner, thus trunk of control rat and the angle between the described base (101).
2. tail-suspended rat positioner according to claim 1 is characterized in that,
The end opening that described big mouse fixed case (104) is higher, and its lower end is provided with rat apparatus for adjusting position (302,301), is used for changing the position of rat at big mouse fixed case (104),
And described tail-suspended rat positioner further comprises: trunk positioning device (204,306,308) is used to make the trunk of rat to fix.
3, tail-suspended rat positioner according to claim 1 is characterized in that, described angle controller comprises a holder (103), and this holder (103) comprising:
Holder chassis (201), it is fixed on the described base (101);
Holder support (202), it is fixed on described holder chassis (201) and goes up and which is provided with a rat trunk by hole (204);
And the below of a higher end of described big mouse fixed case (104) is provided with hook (303), and this hook (303) is used to make described big mouse fixed case (104) and described holder support (202) to be connected and fixed.
4, tail-suspended rat positioner according to claim 1 is characterized in that, described angle controller comprises:
One angle control panel (304), it is set near the lower end of described big mouse fixed case (104), its lower end is fixed on the described base (101), be provided with fixture at its differing heights, be used for a lower end, to regulate the height of a described lower end with respect to described base (101) at the fixing described big mouse fixed case (104) of differing heights;
One bearing arrangement (305), it is fixed on the described base (101), and described big mouse fixed case (104) is fixed on the described bearing arrangement (305) rotationally with respect to described base (101).
5, a kind of tail-suspended rat master/passive exercise training device is used for rat is carried out master/continuous passive motion under the simulated weightlessness, it is characterized in that comprising:
Rat hindlimb telecontrol equipment (105,106) is used for the hind leg of rat is carried out active or continuous passive motion, and it further comprises:
The TRAJECTORY CONTROL device is used to limit the range of movement of rat hindlimb;
The active movement trainer is used for rat hindlimb is carried out the active movement training; With
Passive exercise training device is used for rat hindlimb is carried out continuous passive motion.
6, tail-suspended rat master/passive exercise training device according to claim 5 is characterized in that described TRAJECTORY CONTROL device comprises:
Movement locus confinement plate (407);
Bearing arrangement (406), it is fixed on the base (101) of described motion training device, and described movement locus confinement plate (407) is to be connected on the described bearing arrangement (406) with respect to the rotating mode of described base (101);
Load regulation rubber band (403), the one end is fixing with respect to described base (101), and the other end is fixed on the end of described movement locus confinement plate (407) near rat;
The first sports limiting bar (404), it is set at the end of described bearing arrangement (406) near rat;
The second sports limiting bar (408), it is set at the end of described bearing arrangement (406) away from rat.
7, tail-suspended rat master/passive exercise training device according to claim 6 is characterized in that,
The lower end of the described first sports limiting bar (404) is fixed on the described base (101), and its upper end is provided with a damping cap (405), changes the height of the described first sports limiting bar (404) with the rotation by described damping cap (405);
The lower end of the described second sports limiting bar (408) is fixed on the described base (101), and its upper end is provided with a damping cap (405), changes the height of the described second sports limiting bar (408) with the rotation by described damping cap (405).
8, tail-suspended rat master/passive exercise training device according to claim 6 is characterized in that,
Described master/passive exercise training device further comprises a pair of pedal (401), and it is set at described movement locus confinement plate (407) near the end of rat, is used for placing respectively and the fixing a pair of hind leg of rat;
Described active movement trainer comprises:
Egersimeter (414), its electrode tip are connected on the described pedal (401), are used to give the electro photoluminescence of rat vola;
Single-chip microcomputer is used to control the electro photoluminescence number of times of described egersimeter (414).
9, tail-suspended rat master/passive exercise training device according to claim 6 is characterized in that, described passive exercise training device comprises:
Motor (413), it is fixed on the described base (101);
Backguy (409), the one end is fixed on the turning cylinder (412) of described motor (413), the other end is fixed on the backguy connecting hole (410) of described movement locus confinement plate (407), and described backguy connecting hole (410) is arranged at the end away from rat of described movement locus confinement plate (407).
10, according to any one described tail-suspended rat master/passive exercise training device among the claim 5-9, it is characterized in that further comprising tail-suspended rat positioner as claimed in claim 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810114305XA CN101283675B (en) | 2008-06-06 | 2008-06-06 | Positive/passive exercise training device for simulating weightless tail suspended rats |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810114305XA CN101283675B (en) | 2008-06-06 | 2008-06-06 | Positive/passive exercise training device for simulating weightless tail suspended rats |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009102496443A Division CN101703007B (en) | 2008-06-06 | 2008-06-06 | Positioning device for active/passive exercise training device for simulated weightless tail-suspended rat |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101283675A true CN101283675A (en) | 2008-10-15 |
| CN101283675B CN101283675B (en) | 2010-06-02 |
Family
ID=40056256
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200810114305XA Expired - Fee Related CN101283675B (en) | 2008-06-06 | 2008-06-06 | Positive/passive exercise training device for simulating weightless tail suspended rats |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101283675B (en) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101558991A (en) * | 2009-04-29 | 2009-10-21 | 北京航空航天大学 | Vibration/motion training device for simulating weightless tail suspended rats |
| CN102129801A (en) * | 2011-03-24 | 2011-07-20 | 宋昕宸 | Intelligentized display device of simulated rat in simulated weightlessness condition |
| CN102657101A (en) * | 2012-04-16 | 2012-09-12 | 中国人民解放军63919部队 | Non-human primate test animal medium and long-term weightlessness simulation model device |
| CN104160978A (en) * | 2014-04-25 | 2014-11-26 | 杨成 | Non-straddle small animal hind limb rehabilitation training instrument |
| CN103688877B (en) * | 2013-12-10 | 2016-02-17 | 中国航天员科研训练中心 | Animal simulation low-gravity exercise device |
| CN110481820A (en) * | 2019-08-23 | 2019-11-22 | 天津理工大学 | A kind of rat tails suspension apparatus based on state of weightlessness simulation |
| CN112167090A (en) * | 2020-11-11 | 2021-01-05 | 四川省建研全固建筑新技术工程有限公司 | Animal behavior training and displaying system and method |
| IT201900013242A1 (en) * | 2019-07-29 | 2021-01-29 | Alberto Longhin | DEVICE FOR THE PHYSIOTHERAPY REHABILITATION OF ANIMALS |
| CN113229214A (en) * | 2021-05-19 | 2021-08-10 | 齐齐哈尔医学院 | Traumatic osteoarthritis rat experimental model and construction method |
| CN113287533A (en) * | 2020-02-24 | 2021-08-24 | 天津大学 | Simulated space compound environment experimental device suitable for rat and use method thereof |
-
2008
- 2008-06-06 CN CN200810114305XA patent/CN101283675B/en not_active Expired - Fee Related
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101558991A (en) * | 2009-04-29 | 2009-10-21 | 北京航空航天大学 | Vibration/motion training device for simulating weightless tail suspended rats |
| CN102129801A (en) * | 2011-03-24 | 2011-07-20 | 宋昕宸 | Intelligentized display device of simulated rat in simulated weightlessness condition |
| CN102657101A (en) * | 2012-04-16 | 2012-09-12 | 中国人民解放军63919部队 | Non-human primate test animal medium and long-term weightlessness simulation model device |
| CN103688877B (en) * | 2013-12-10 | 2016-02-17 | 中国航天员科研训练中心 | Animal simulation low-gravity exercise device |
| CN104160978A (en) * | 2014-04-25 | 2014-11-26 | 杨成 | Non-straddle small animal hind limb rehabilitation training instrument |
| IT201900013242A1 (en) * | 2019-07-29 | 2021-01-29 | Alberto Longhin | DEVICE FOR THE PHYSIOTHERAPY REHABILITATION OF ANIMALS |
| CN110481820A (en) * | 2019-08-23 | 2019-11-22 | 天津理工大学 | A kind of rat tails suspension apparatus based on state of weightlessness simulation |
| CN110481820B (en) * | 2019-08-23 | 2024-03-08 | 天津理工大学 | Rat tail suspension device based on weightlessness status simulation |
| CN113287533A (en) * | 2020-02-24 | 2021-08-24 | 天津大学 | Simulated space compound environment experimental device suitable for rat and use method thereof |
| CN112167090A (en) * | 2020-11-11 | 2021-01-05 | 四川省建研全固建筑新技术工程有限公司 | Animal behavior training and displaying system and method |
| CN112167090B (en) * | 2020-11-11 | 2023-05-02 | 四川省建研全固建筑新技术工程有限公司 | Animal behavior training and displaying system and method |
| CN113229214A (en) * | 2021-05-19 | 2021-08-10 | 齐齐哈尔医学院 | Traumatic osteoarthritis rat experimental model and construction method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101283675B (en) | 2010-06-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101283675B (en) | Positive/passive exercise training device for simulating weightless tail suspended rats | |
| CN101703007B (en) | Positioning device for active/passive exercise training device for simulated weightless tail-suspended rat | |
| CN100417577C (en) | Astronaut exercising apparatus | |
| CN101972196B (en) | Lower-limb motion recovery machine with multiple body positions | |
| Sato et al. | A cyborg beetle: insect flight control through an implantable, tetherless microsystem | |
| Aune et al. | Effect of physical fatigue on motor control at different skill levels | |
| CN101558991A (en) | Vibration/motion training device for simulating weightless tail suspended rats | |
| Ivanenko et al. | Gait transitions in simulated reduced gravity | |
| CN101107049A (en) | Training apparatus | |
| WO2016178393A1 (en) | Model-animal functional-improvement evaluation apparatus and nerve-cell culturing apparatus | |
| CN104144666B (en) | Exercise therapy method and exercise therapy instrument | |
| CN102302823A (en) | Automatic transcranial magnetic stimulation (TMS) regulation and control method based on motion path planning | |
| CN105997432B (en) | A kind of medical treatment device of aiding upright | |
| CN201861910U (en) | Multi-body position lower limb exercise rehabilitation machine | |
| CN109830158A (en) | A kind of knee joint dynamic analog device | |
| CN203303610U (en) | Vibrating super-equal-length shot put special-strength trainer | |
| CN107875509B (en) | transcranial direct current stimulation system | |
| CN110251896A (en) | A kind of upper limb auxiliary mechanical arm | |
| RU2560511C2 (en) | Training apparatus for teaching walking | |
| Alipour-Haghighi et al. | Tetanic response of the cricothyroid muscle | |
| CN211188935U (en) | Psychology is with harmony trainer | |
| CN108379041A (en) | Tired the bionical of eye diseases such as hypometropia that can prevent does not use eye system for a kind of long-time eye | |
| Sayenko et al. | Characteristics of postural corrective responses before and after long-term spaceflights | |
| CN108207806B (en) | Portable experimental animals is with wearable amazing device of eyesight | |
| CN207085247U (en) | A kind of sports dancing overturns training aids |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20100602 Termination date: 20120606 |