CN101278838A - Multichannel respiratory physiological signal wireless monitoring system and method - Google Patents

Multichannel respiratory physiological signal wireless monitoring system and method Download PDF

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CN101278838A
CN101278838A CNA200810027770XA CN200810027770A CN101278838A CN 101278838 A CN101278838 A CN 101278838A CN A200810027770X A CNA200810027770X A CN A200810027770XA CN 200810027770 A CN200810027770 A CN 200810027770A CN 101278838 A CN101278838 A CN 101278838A
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CN101278838B (en
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罗远明
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Guangzhou Ruishibo Medical Technology Co ltd
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Abstract

The invention provides a multi-channel respiratory physiological signal wireless monitoring system, which comprises a sensor, a data acquisition sending terminal, a data receiving terminal and a PC and the sensor, the data acquisition sending terminal, the data receiving terminal and the PC are connected in sequence. The sensor is arranged on a diaphragm signal detection tube or a multi-functional respiratory signal detection tube of a patient; the acquisition sending terminal comprises a power supply module and a multi-channel signal amplifier module, an AD conversion module, an MCU acquisition and a transmission control module and a wireless transmission module, the multi-channel signal amplifier module, the AD conversion module, the MCU acquisition and the transmission control module and the wireless transmission module are connected in sequence. The power supply module is respectively connected with the multi-channel signal amplifier module, the AD conversion module, the MCU acquisition and transmission control module and the wireless transmission module. The receiving terminal comprises a wireless receiving module and an MCU receiving control module which are mutually connected and the MCU receiving control module is connected with the PC. The patient carrying the acquisition sending terminal can transmit 5-channel diaphragm myoelectric signal or cardiac electric signal, 3-channel respiratory pressure and flow signal to a remote monitoring center by the way of wireless, thus achieving the real-time display, storage, analysis and treatment of multi-channel signal.

Description

Multichannel respiratory physiological signal wireless monitoring system and method
Technical field
The present invention relates to remote measurement wireless monitoring technology, specifically be meant multichannel respiratory physiological signal wireless monitoring system and method.
Background technology
Based on GSM (Global System for Mobile Communications) and GPRS (GeneralPacket Radio Service) though wireless monitoring instrument mobility strong but message transmission rate is low, transmitting power is big, and has only a passage usually.Then transmission range is shorter based on the remote measurement wireless monitoring instrument of Bluetooth technology, uses limited.
The diagnosis and treatment of respiratory disorder depend on the monitoring of breath signal, and the wireless monitor of breath signal is to the evaluation of gait test in 6 minutes, and the monitoring of the patient in the ward has great value.Still there is not multichannel breath signal wireless monitoring system at present.The breath signal wireless monitoring system requires to obtain simultaneously biological small-signals such as multichannel diaphram myoelectricity, electrocardio, respiratory pressure and respiratory air flow.For example the electromyographic signal amplitude may have only several microvolts, but its frequency is higher, up to 500Hz.The frequency of respiratory pressure and respiratory air flow signal is then mainly in the 0-20Hz scope.Realize that the various breathing bio signals of undistorted collection comprise diaphram myoelectricity, respiratory pressure and respiratory air flow signal, require high sampling rate.In addition, breathe the wireless monitoring instrument and require light carrying, in real time monitoring.Still there is not to grow the various respiratory physiological signal simultaneously the technology of distance (reaching 100 meters) high accuracy, real-time telemetry at present.
Summary of the invention
The objective of the invention is to overcome the shortcoming of above-mentioned prior art with not enough, a kind of multichannel respiratory physiological signal wireless monitoring system and method are provided, the experimenter only need wear portable signals collecting transmitting terminal just can be the 5 passage diaphragm muscle signal of telecommunication or electrocardiosignaies, 3 passage respiratory pressures and flow signal are sent to the monitoring center of far-end by wireless mode, and the monitoring center can be carried out in real time or afterwards demonstration, storage, analysis and processing multi channel signals.
Purpose of the present invention realizes by following proposal: this multichannel respiratory physiological signal wireless monitoring system, comprise the pick off that connects successively, the data acquisition transmitting terminal, data receiver and PC, described pick off is to be placed on patient's diaphram signal detection pipe or multifunctional breath signal detection pipe on one's body, described data acquisition transmitting terminal comprises power module and the multi channel signals amplification module that connects successively, A/D gathers and modular converter, the MCU control module, wireless transmitter module, described power module while and multi channel signals amplification module, A/D gathers and modular converter, MCU gathers the emission control module, wireless transmitter module connects respectively; Described data receiver comprises that interconnective wireless receiving module, MCU receive control module, and described MCU receives control module and is connected with PC.
For realizing the present invention better, described data acquisition transmitting terminal is carried by the experimenter; Described data receiver is placed on far-end monitoring chamber.
Described multi channel signals amplification module comprises that connection successively has high input impedance, high rejection ratio altogether and low noise, low temperature and floats the amplifier module and the multichannel analog switch of ability; This amplifier module includes amplifier, wave filter and the 50HZ wave trap that connects successively.
Described A/D gathers and the effect of modular converter is that the multi-channel analog signal of amplification module output is converted to digital signal.Because diaphragm muscle signal of telecommunication amplitude is very faint, so needing high-precision A/D to gather with modular converter samples to it, described A/D gathers with modular converter and adopts 16 high-accuracy data acquisition chips so that use in real time, because the diaphragm muscle signal of telecommunication frequency higher (most of frequency distribution is at 20-250Hz) that native system will be monitored, therefore A/D collection here is taken as 1kHz with the sample rate of modular converter, and sampling process is gathered the emission control module controls by MCU.
It is single-chip microcomputer that described MCU gathers the emission control module, it is the core of whole data collection transmitting terminal, here select 16 single-chip microcomputers for use, adopt the common batteries power supply also can keep the requirement that the native system long-time continuous is used to satisfy with advantages such as super low-power consumption, the speed of service are fast, aboundresources, disposal ability are strong, exploitation is convenient.
It equally also is 16 single-chip microcomputers that described MCU receives control module, and it can be connected with the PC main frame by the USB transport module.
Consider factors such as the far away and transmitting power of wireless transmission rate height, the distance of 8 passage breath signal wireless monitoring system requirements is lower, and GPRS network and Bluetooth technology all can't all satisfy above-mentioned requirements, and electric channel mainly is set at 315,433,868 and the frequency band of 915MHz.Described wireless transmitter module of native system and wireless receiving module are to be provided with one to one, adopt MSK modulation demodulation system, fixed-length data pack mode, working frequency range is the uhf band of 433MHz, adopt the mode of frequency division multiple access, the bandwidth of each passage is 200khz, transfer rate is 500kbps, and transmitting power is 10dbm.
The power module of described data acquisition transmitting terminal adopts low power dissipation design, and its active voltage scope is 2.5V-3.2V, but the native system continuous operation is more than 2 hours; Power module comprises power supply and the booster, linear voltage regulator, the diode stabilivolt that connect respectively, and described power supply can be common batteries or lithium battery, and described booster, linear voltage regulator, diode stabilivolt are formed the voltage stabilizing electric channel.Physiological signal is a small-signal, requires system that strong anti-interference ability and ultra-low noise design are arranged.Power module provides required various supply voltages for each module of data acquisition transmitting terminal, and the performance of power module is determining the performance of system.The supply voltage of each module of data acquisition transmitting terminal has+5V ,+3.3V and+2V.Cell output voltage needs to boost to+5V through booster, and the voltage of 3.3V can be obtained by linear voltage regulator, and+2V voltage can obtain by the diode stabilivolt.Booster and linear voltage regulator should adopt the chip that has low noise, hangs down advantages such as ripple, high efficiency, to guarantee the accuracy of image data.
Adopt above-mentioned multichannel respiratory physiological signal wireless monitoring system to carry out the method for multichannel respiratory physiological signal wireless monitoring, be meant the multinomial respiratory physiological signal of data acquisition transmitting terminal by pick off continuous acquisition experimenter, mode by radio communication, data are sent to the data receiver of far-end monitoring chamber and store in the computer, carry out respective handling by main frame according to the physiological signal that receives, its concrete steps are:
(1) carries out initialization behind the system power-on reset earlier, select working method, enter low-power consumption mode then, wait for that MCU gathers the sample clock generator interruption of emission control module;
(2) the multi channel signals amplification module to the multi channel signals processing and amplifying after, MCU gathers the method that the emission control module adopts the sampling break in service, the multi channel signals amplification module is carried out gating control, gather with modular converter by A/D and successively multi-channel analog signal is sampled; A/D gathers with modular converter the sampled signal data is carried out being sent to wireless transmitter module after the A/D conversion, gathers emission control module controls wireless transmitter module by MCU data wireless is sent to data receiver;
(3) data receiver receives the signal that the wireless transmitter module by the data acquisition transmitting terminal sends over and deposits MCU in by wireless receiving module and receives control module, MCU receive control module control USB transport module transfer of data to the PC main frame;
(4) carry out the then attainable real-time demonstration of respective handling, storage, analysis and processing by the PC main frame according to the different physiological signal that receives, thereby realize the monitoring of multi channel signals parameter.
For realizing the present invention better, the interrupt timing of the described sample clock generator of step (1) is 1ms, promptly sets the sample frequency of 1k.
The method of the described sampling break in service of step (2) is carried out gating control to the multi channel signals amplification module, gathers with modular converter by A/D and successively multi-channel analog signal is sampled, and concrete steps are:
After sample clock generator interrupt to produce, MCU gathered the clear house dog of emission control module, prevented from that house dog is overtime to reset, and judged whether to have gathered each channel signal:
If do not gathered each channel signal, then MCU gathers emission control module controls A/D collection and gathers current channel signal and preservation with modular converter, and then next passage of multichannel analog switching gate of control multi channel signals amplification module, the above process that circulates is until handling 8 channel signals;
If gathered each channel signal, then MCU gathers multichannel analog switching gate 0 passage of emission control module controls multi channel signals amplification module, in order to the next round sampling; Whether judgment data expires 32 bytes, if then the wireless transmission data withdraw from breaking, if not, then directly withdraws from interruption.
Described multi channel signals amplification module comprises the step of signal processing and amplifying: the amplifier of multi channel signals amplification module comprises that diaphram Ji Dian respiratory pressure and airflow signal amplify back filtering, trap to the multichannel breath signal of input, by the prepass of working as of multichannel analog switching gate, input A/D gathers the input with modular converter then.
The present invention has following advantage and effect with respect to prior art: data acquisition transmitting terminal of the present invention has microminiaturization, carries, the low-power consumption working time is long, sampling rate is high, the little characteristics of distortion; Native system comprises that to breath signal the diaphragm muscle signal of telecommunication, electrocardiosignal respiratory pressure signal and flow carry out wireless collection, transmission first.The experimenter only need wear the signal data acquisition transmitting terminal just can be sent to far-end to breath signal or the electrocardiosignal up to 8 passages by wireless mode ICU, monitoring in real time shows, stores, analyzes and handle or treats further analyzing and processing of back, thus the wireless monitor of realization breath signal.
Description of drawings
Fig. 1 is the structural representation that the present invention is based on the multi channel signals parameter monitor system of wireless data transmission communication;
Fig. 2 is the internal structure sketch map of multi channel signals amplification module shown in Figure 1;
Fig. 3 is the sampling interrupt service routine flow chart that the present invention is based on the multi channel signals parameter monitoring method of wireless data transmission communication.
The specific embodiment
Below in conjunction with embodiment and accompanying drawing the present invention is described in further detail, but embodiments of the present invention are not limited thereto.
Embodiment
As shown in Figure 1, this multichannel respiratory physiological signal wireless monitoring system, comprise the pick off that connects successively, the data acquisition transmitting terminal, data receiver and PC, described pick off is to be placed on patient's diaphram signal detection pipe or multifunctional breath signal detection pipe on one's body, described data acquisition transmitting terminal comprises power module and the multi channel signals amplification module that connects successively, A/D gathers and modular converter, the MCU control module, wireless transmitter module, described power module while and multi channel signals amplification module, A/D gathers and modular converter, MCU gathers the emission control module, wireless transmitter module connects respectively; Described data receiver comprises that interconnective wireless receiving module, MCU receive control module, and described MCU receives control module and is connected with PC.
Described data acquisition transmitting terminal is carried by the experimenter; Described data receiver is placed on far-end monitoring chamber.
As shown in Figure 2, described multi channel signals amplification module comprises that connection successively has high input impedance, high rejection ratio altogether and low noise, low temperature and floats the amplifier module and the multichannel analog switch of ability; This amplifier module includes wave filter and the 50HZ wave trap that connects successively.
Described A/D gathers and modular converter adopts 16 high-accuracy data acquisition chips so that use in real time, and this A/D gathers and the sample rate of modular converter is taken as 1kHz, and sampling process is gathered the emission control module controls by MCU.
Described MCU gather emission control module, MCU receive control module adopt have super low-power consumption, 16 single-chip microcomputers of advantages such as the speed of service is fast, aboundresources, disposal ability is strong, exploitation is convenient are single-chip microcomputer, described MCU receives control module and is connected with the PC main frame by the USB transport module.
Consider factors such as the far away and transmitting power of wireless transmission rate height, the distance of 8 passage breath signal wireless monitoring system requirements is lower, and GPRS network and Bluetooth technology all can't all satisfy above-mentioned requirements, and electric channel mainly is set at 315,433,868 and the frequency band of 915MHz.Wireless transmitter module of the present invention adopts the CC1100 wireless data transmission chip of Chipcon company, and its maximum transmission power only is 10dbm, and under 1.2kbps data transmission rate and 1% data packet error rate, receiving sensitivity is up to-110dBm.This RF transceiving chip is integrated highly configurable modem, it supports different modulation formats, data transmission rate can reach 500kbps.CC1100 also provides hardware supported widely for processing data packets, data buffering, burst transfers of data, clear channel estimating, the indication of chain channel quality.The main operating parameters of CC1100 and 64 emission/reception FIFO (FIFO stack) can be by the MCU control module by the controls of SPI interface.
Because CC1100 does not need much other external electric channels, each parameter of chip can be set flexibly by MCU as requested.Described wireless transmitter module of native system and wireless receiving module are to be provided with one to one, adopt MSK modulation demodulation system, fixed-length data pack mode, working frequency range is the uhf band of 433MHz, adopt the mode of frequency division multiple access, the bandwidth of each passage is 200khz, transfer rate is 500kbps, and transmitting power is 10dbm.
The power module of described data acquisition transmitting terminal adopts low power dissipation design, and its active voltage scope is 2.5V-3.2V, but the native system continuous operation is more than 2 hours; Power module comprises power supply and the booster, linear voltage regulator, the diode stabilivolt that connect respectively, and described power supply can be common batteries or lithium battery, and described booster, linear voltage regulator, diode stabilivolt are formed the voltage stabilizing electric channel.Physiological signal is a small-signal, requires system that strong anti-interference ability and ultra-low noise design are arranged.Power module provides required various supply voltages for each module of data acquisition transmitting terminal, and the performance of power module is relevant with the performance of system.The supply voltage of each module of data acquisition transmitting terminal has+5V ,+3.3V and+2V.Cell output voltage needs to boost to+5V through booster, and the voltage of 3.3V can be obtained by linear voltage regulator, and+2V voltage can obtain by the diode stabilivolt.Booster and linear voltage regulator should adopt the chip that has low noise, hangs down advantages such as ripple, high efficiency, to guarantee the accuracy of image data.
As shown in Figure 1, adopt the work process of above-mentioned multichannel respiratory physiological signal wireless monitoring system, be meant the multinomial respiratory physiological signal of data acquisition transmitting terminal by pick off continuous acquisition experimenter, mode by radio communication, data are sent to the data receiver of far-end monitoring chamber and store in the computer, carry out respective handling by main frame according to the physiological signal that receives, its concrete steps are:
(1) carries out initialization behind the system power-on reset earlier, select working method, enter low-power consumption mode then, wait for that MCU gathers the sample clock generator interruption of emission control module;
(2) the multi channel signals amplification module to the multi channel signals processing and amplifying after, MCU gathers the method that the emission control module adopts the sampling break in service, the multi channel signals amplification module is carried out gating control, gather with modular converter by A/D and successively multi-channel analog signal is sampled; A/D gathers with modular converter the sampled signal data is carried out being sent to wireless transmitter module after the A/D conversion, gathers emission control module controls wireless transmitter module by MCU data wireless is sent to data receiver;
(3) data receiver receives the signal that the wireless transmitter module by the data acquisition transmitting terminal sends over and deposits MCU in by wireless receiving module and receives control module, MCU receive control module control USB transport module transfer of data to the PC main frame;
(4) carry out the then attainable real-time demonstration of respective handling, storage, analysis and processing by the PC main frame according to the different physiological signal that receives, thereby realize the monitoring of multi channel signals parameter.
The interrupt timing of the described sample clock generator of step (1) is 1ms, promptly sets the sample frequency of 1k.
As shown in Figure 3, the method for the described sampling break in service of step (2) is carried out gating control to the multi channel signals amplification module, gathers with modular converter by A/D and successively multi-channel analog signal is sampled, and concrete steps are:
After sample clock generator interrupt to produce, MCU gathered the clear house dog of emission control module, prevented from that house dog is overtime to reset, and judged whether to have gathered each channel signal:
If do not gathered each channel signal, then MCU gathers emission control module controls A/D collection and gathers current channel signal and preservation with modular converter, and then next passage of multichannel analog switching gate of control multi channel signals amplification module, the above process that circulates is until handling 8 channel signals;
If gathered each channel signal, then MCU gathers multichannel analog switching gate 0 passage of emission control module controls multi channel signals amplification module, in order to the next round sampling; Whether judgment data expires 32 bytes, if then the wireless transmission data withdraw from breaking, if not, then directly withdraws from interruption.
As shown in Figure 2, described multi channel signals amplification module comprises the step of signal processing and amplifying: the amplifier module of multi channel signals amplification module comprises diaphram Ji Dian respiratory pressure to the multichannel breath signal of input and airflow signal amplifies and filtering, trap, by the prepass of working as of multichannel analog switching gate, input A/D gathers the input with modular converter then.
As mentioned above; just can realize the present invention preferably; the foregoing description is a preferred implementation of the present invention; but embodiment of the present utility model is not restricted to the described embodiments; other any do not deviate from change, the modification done under spirit of the present utility model and the principle, substitutes, combination, simplify; all should be the substitute mode of equivalence, be included within the protection domain of the present utility model.

Claims (9)

1, multichannel respiratory physiological signal wireless monitoring system, it is characterized in that: comprise the pick off that connects successively, the data acquisition transmitting terminal, data receiver and PC, described pick off is to be placed on patient's diaphram signal detection pipe or multifunctional breath signal detection pipe on one's body, described data acquisition transmitting terminal comprises power module and the multi channel signals amplification module that connects successively, A/D gathers and modular converter, the MCU control module, wireless transmitter module, described power module while and multi channel signals amplification module, A/D gathers and modular converter, MCU gathers the emission control module, wireless transmitter module connects respectively; Described data receiver comprises that interconnective wireless receiving module, MCU receive control module, and described MCU receives control module and is connected with PC.
2, according to the described multichannel respiratory physiological signal wireless monitoring system of claim 1, it is characterized in that: described data acquisition transmitting terminal is carried by the experimenter; Described data receiver is placed on far-end monitoring chamber.
3, according to the described multichannel respiratory physiological signal wireless monitoring system of claim 1, it is characterized in that: described multi channel signals amplification module comprises amplifier module and the multichannel analog switch that connects successively; Described amplifier module includes amplifier, wave filter and the 50HZ wave trap that connects successively.
4, according to the described multichannel respiratory physiological signal wireless monitoring system of claim 1, it is characterized in that: described A/D gathers with modular converter and adopts 16 high-accuracy data acquisition chips, and sample rate is taken as 1kHz.
5, according to the described multichannel respiratory physiological signal wireless monitoring system of claim 1, it is characterized in that: described MCU gathers the emission control module, MCU receives control module and adopts 16 single-chip microcomputers, and described MCU receives control module and is connected with the PC main frame by the USB transport module.
6, according to the described multichannel respiratory physiological signal wireless monitoring system of claim 1, it is characterized in that: described wireless transmitter module and wireless receiving module are to be provided with one to one, adopt MSK modulation demodulation system, fixed-length data pack mode, working frequency range is the uhf band of 433MHz, adopt the mode of frequency division multiple access, the bandwidth of each passage is 200khz, and transfer rate is 500kbps, and transmitting power is 10dbm.
7, adopt the multichannel respiratory physiological signal wireless monitoring method of each described multichannel respiratory physiological signal wireless monitoring system of claim 1-6, it is characterized in that: the data acquisition transmitting terminal is by pick off continuous acquisition experimenter's multinomial respiratory physiological signal, mode by radio communication, data are sent to the data receiver of far-end monitoring chamber and store in the computer, carry out respective handling by main frame according to the physiological signal that receives, its concrete steps are:
(1) carries out initialization behind the system power-on reset earlier, select working method, enter low-power consumption mode then, wait for that MCU gathers the sample clock generator interruption of emission control module;
(2) the multi channel signals amplification module to the multi channel signals processing and amplifying after, MCU gathers the method that the emission control module adopts the sampling break in service, the multi channel signals amplification module is carried out gating control, gather with modular converter by A/D and successively multi-channel analog signal is sampled; A/D gathers with modular converter the sampled signal data is carried out being sent to wireless transmitter module after the A/D conversion, gathers emission control module controls wireless transmitter module by MCU data wireless is sent to data receiver;
(3) data receiver receives the signal that the wireless transmitter module by the data acquisition transmitting terminal sends over and deposits MCU in by wireless receiving module and receives control module, MCU receive control module control USB transport module transfer of data to the PC main frame;
(4) carry out the then attainable real-time demonstration of respective handling, storage, analysis and processing by the PC main frame according to the different physiological signal that receives, thereby realize the monitoring of multi channel signals parameter.
8, according to the described multichannel respiratory physiological signal wireless monitoring method of claim 7, it is characterized in that: the interrupt timing of the described sample clock generator of step (1) is 1ms, promptly sets the sample frequency of 1k;
The method of the described sampling break in service of step (2) is carried out gating control to the multi channel signals amplification module, gathers with modular converter by A/D and successively multi-channel analog signal is sampled, and concrete steps are:
After sample clock generator interrupt to produce, MCU gathered the clear house dog of emission control module, prevented from that house dog is overtime to reset, and judged whether to have gathered each channel signal:
If do not gathered each channel signal, then MCU gathers emission control module controls A/D collection and gathers current channel signal and preservation with modular converter, and then next passage of multichannel analog switching gate of control multi channel signals amplification module, the above process that circulates is until handling 8 channel signals;
If gathered each channel signal, then MCU gathers multichannel analog switching gate 0 passage of emission control module controls multi channel signals amplification module, in order to the next round sampling; Whether judgment data expires 32 bytes, if then the wireless transmission data withdraw from breaking, if not, then directly withdraws from interruption.
9, according to the described multichannel respiratory physiological signal wireless monitoring method of claim 7, it is characterized in that: described multi channel signals amplification module comprises the step of signal processing and amplifying: the amplifier module of multi channel signals amplification module comprises diaphram Ji Dian respiratory pressure to the multichannel breath signal of input and airflow signal amplifies and filtering, trap, by the prepass of working as of multichannel analog switching gate, input A/D gathers the input with modular converter then.
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