CN101249246B - Proprietary Chinese medicine preparations for curing depression after cerebral infarction - Google Patents
Proprietary Chinese medicine preparations for curing depression after cerebral infarction Download PDFInfo
- Publication number
- CN101249246B CN101249246B CN2008100147443A CN200810014744A CN101249246B CN 101249246 B CN101249246 B CN 101249246B CN 2008100147443 A CN2008100147443 A CN 2008100147443A CN 200810014744 A CN200810014744 A CN 200810014744A CN 101249246 B CN101249246 B CN 101249246B
- Authority
- CN
- China
- Prior art keywords
- parts
- preparation
- depression
- cerebral infarction
- root
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention provides a Chinese patent medicine preparation for curing the depression after cerebral infarction. The invention comprises the drugs calculated according to the proportion by weight as follows: 10 to 20 parts of rhizome of Sichuan lovage, 6 to 10 parts of bupleurum root, 6 to 15 parts of polygala root, 10 to 20 parts of Chinese angelica root, 10 to 30 parts of root of herbaceous peony, 10 to 15 parts of curcuma root, 10 to 20 parts of safflower, 15 to 25 parts of arboruitae seed and 30 to 50 parts of parched wild jujube seed. The Chinese patent medicine preparation adopts the preparation method that the Chinese drug materials are ground into fine powder of more than 100 meshes according to the formulation, and are uniformly mixed, the ozone sterilization processing is performed for 20 minutes, the materials are mixed with honey and stirred uniformly, and then is processed into pill dosage form or capsule dosage form. The preparation is a pure herbal preparation, and has the advantages that the curative effect is remarkable, the production method is simple, the cost is low, the toxic and side effects are less, the preparation is easy to be accepted by the patient, the drugs are mutually combined and has the functions of dispersing and rectifying the depressed liver-energy, stimulating circulation to end stasis, eliminating sputum, inducing resuscitation, waking up the patient from inconsciousness and allaying restlessness, the preparation can be used for curing the depression after cerebral infarction with remarkable curative effect and no obvious toxic and side effects.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine preparation for the treatment of depression after cerebral infarction, belong to technical field of Chinese medicines.
Background technology
Apoplexy is the commonly encountered diseases and the frequently-occurring disease of middle-aged and elderly people, and the apoplexy retarded depression is one of common complication after the apoplexy, and is wherein more common with depression after cerebral infarction.According to statistics, the incidence rate of apoplexy retarded depression disease is about 22-60%, and is higher because of its sickness rate, has a strong impact on the initiative and the enthusiasm of patient's Fighting Disease again, and the rehabilitation of patient function of nervous system and patient's prognosis are caused harmful effect.So active and effective treatment apoplexy retarded depression not only alleviates patient's psychic pain, improve the quality of living, can increase the compliance of patient simultaneously to treatment, be the problem that is worth the medical personnel to inquire into.
The pathogenesis of depression after cerebral infarction it be not immediately clear, mainly contains constitutional endogenous mechanism theory, i.e. cause that the dysequilibrium between norepinephrine and the 5-hydroxy tryptamine (5-HT) is relevant behind the generation of depression after cerebral infarction and the brain damage.Clinical western medicine depression after cerebral infarction is mainly used traditional tricyclic antidepressant (, amitriptyline bright as miboplatin), second filial generation antidepressants norepinephrine and serotonin reuptake inhibitor, selective serotonin reuptake inhibitor etc. (as fluoxetine, paroxetine).These medicines not only have unicity in treatment, side effect is big but also need long-term prescription, medical expense costliness, and the patient is poor to drug compliance simultaneously.
From the Chinese medical discrimination angle analysis, the existing strongly fragrant state of an illness will of depression after cerebral infarction is not relaxed, the characteristics of functional activity of QI being not smooth, and the characteristics of apoplexy are arranged again, with disorder of QI and blood, phlegm and blood stasis, on disturb clearly key, mind disorder is relevant, Chinese medical discrimination belongs to melancholia after being ill.Treatment based on soothing liver-QI for relieving depression, activating blood circulation to dissipate blood stasis, eliminate the phlegm, calm the nerves and have one's ideas straightened out, improve depressive symptom thereby reach, the accelerator nerve cytothesis promotes the purpose of neurological rehabilitation.Chinese medicine will show remarkable advantages especially in the treatment clinical course of depression after cerebral infarction.
The treatment depression after cerebral infarction adopts the Chinese patent medicine of treatment cerebral infarction and the Chinese patent medicine of treatment depression to use simultaneously more at present, as add the flavor Herba Sidae Rhombifoliae soup and close Folium Ginkgo, resolving stagnation for tranquilization ball and share treatment post-stroke depression diseases such as thorn five first injection, as reaching the obvious treatment effect by the doctor's advice medication, but because medical expenses height, the medication inconvenience, very poor to drug compliance, have a strong impact on therapeutic effect.
Summary of the invention
The present invention is directed to the deficiency of the Chinese and western medicine medicine existence of existing treatment depression after cerebral infarction, provide that a kind of therapeutic effect is good, toxic and side effects is little, expense is cheap, the Chinese patent medicine preparation of the treatment depression after cerebral infarction of taking convenience, a kind of preparation method of this Chinese patent medicine preparation is provided simultaneously.
The Chinese patent medicine preparation of treatment depression after cerebral infarction of the present invention comprises following Chinese medicine raw materials by weight proportion:
Rhizoma Chuanxiong 10-20, Radix Bupleuri 6-10, Radix Polygalae 6-15, Radix Angelicae Sinensis 10-20, Radix Paeoniae Alba 10-30, Radix Curcumae 10-15, Flos Carthami 10-20, Semen Platycladi 15-25 and Semen Ziziphi Spinosae (parched) 30-50.
Above-mentioned raw material of Chinese medicine can be from " finding its another name, the place of production and usage Chinese pharmacopoeia and other Chinese medicine handbooks, the function and the pharmacological thereof of each Chinese medicine of distinguishing the flavor of are: Rhizoma Chuanxiong, Radix Angelicae Sinensis, Flos Carthami are in order to invigorate blood circulation, to change silt, collateral dredging, promote organism metabolism, improve blood supply in brain, improve the cerebral cortex irritability; The Radix Bupleuri dispersing the stagnated live-QI to relieve the stagnation of QI; Radix Angelicae Sinensis, Radix Paeoniae Alba nourishing blood to suppress the hyperactive liver; Radix Curcumae goes into QI and blood, and promoting QI circulation for relieving depression, removing heat from blood clear away heart-fire, and cooperates the Chinese Angelica blood replonishing resolving depression effect of invigorating blood circulation stronger; Radix Polygalae, Semen Platycladi, Semen Ziziphi Spinosae (parched) nourishing blood to tranquillize the mind; Radix Polygalae is eliminated the phlegm and is had one's ideas straightened out, tranquilizing the mind.More than all medicine mutually 5, altogether long memorial liver and qi, activating blood circulation to dissipate blood stasis, eliminate the phlegm have one's ideas straightened out, the effect of refreshment and tranquilization, can treat depression after cerebral infarction and evident in efficacy, no obvious toxic-side effects.
The preparation method of Chinese patent medicine preparation of the present invention is:
Getting each raw material of Chinese medicine Rhizoma Chuanxiong, Radix Bupleuri, Radix Polygalae, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Curcumae, Flos Carthami, Semen Platycladi and the common grinding and processing of Semen Ziziphi Spinosae (parched) by prescription becomes above the fine powder more than 100 orders, mix homogeneously, ozone sterilization 20 minutes, add Mel with each raw material of Chinese medicine gross weight identical weight, mix well, be processed into the pill dosage form or make capsule formulation.
Clinical treatment situation of the present invention:
1 case data: male's 25 examples, women's 18 examples; Age 48-78 year, 62.3 years old mean age; Depression course of disease January-May.All selected patients all are diagnosed as Patients with Cerebral Infarction through cranium brain CT or MRI, previously do not have psychological obstacle and mental sickness family history, realize clear, no aphasia and disturbance of intelligence, and mark and clinical symptoms meets the diagnosis of depression according to Han Midun scale (HMAD).Depressed 27 examples of its mild or moderate, depressed 13 examples of moderate, severe depression 3 examples.The all inactive various antidepressants of patient before the treatment.
2 Therapeutic Method: 4 of 2 of capsules (every 0.3 gram) or sweet pills (every 0.5 gram), one day 3 times, warm water delivery service, be a course of treatment February.
3 efficacy evaluations: (1) recovery from illness: the mental symptom complete obiteration, HMAD subtracts branch rate 〉=80%.(2) produce effects: mental symptom is most of to disappear, and HMAD subtracts branch rate 〉=60%.(3) effective: mental symptom obviously alleviates, and HMAD subtracts branch rate 40%.(4) invalid: mental symptom is improved not obvious, and HMAD subtracts branch rate＜25%.
4 therapeutic effect see the following form:
Recovery from illness (example) produce effects (example) is (example) invalid (example) effectively
Slight depressed (27 example) 19 71
Moderate depression (13 example) 4621
Severe depression (3 example) 0021
As seen from the above table: Chinese patent medicine preparation total effective rate of the present invention reaches 95.3%, and cure rate reaches 53.5%.To light, the depressed curative effect of moderate is rather good, tangible untoward reaction does not appear in and short treating period in therapeutic process, the patient compliance is good.But not good enough to the severe depression therapeutic effect, should cooperate antidepressant western medicine in a small amount.The present invention is a pure Chinese medicinal preparation, and therapeutic effect is obvious, and production method is simple, and is with low cost, and toxic and side effects is little, and the patient is acceptant.
The specific embodiment
Embodiment 1
Rhizoma Chuanxiong 10 grams, Radix Bupleuri 6 grams, Radix Polygalae 15 grams, Radix Angelicae Sinensis 10 grams, the Radix Paeoniae Alba 20 grams, Radix Curcumae 15 grams, Flos Carthami 20 grams, Semen Platycladi 25 grams and the common grinding and processing of Semen Ziziphi Spinosae (parched) 30 grams are become fine powder, cross 100 orders with top sieve, mix homogeneously, ozone sterilization 20 minutes, add 151 gram Mel, mix well, be processed into sweet pill routinely, every pill is adorned 0.5 gram.One day 3 times, each 3-4 grain, warm water delivery service, be a course of treatment February.
Embodiment 2
Rhizoma Chuanxiong 15 grams, Radix Bupleuri 10 grams, Radix Polygalae 6 grams, Radix Angelicae Sinensis 20 grams, the Radix Paeoniae Alba 25 grams, Radix Curcumae 12 grams, Flos Carthami 15 grams, Semen Platycladi 20 grams and the common grinding and processing of Semen Ziziphi Spinosae (parched) 40 grams are become fine powder, cross 100 orders with top sieve, mix homogeneously, ozone sterilization 20 minutes, add 163 gram Mel, mix well, be processed into sweet pill routinely, every pill is adorned 0.5 gram.One day 3 times, each 3-4 grain, warm water delivery service, be a course of treatment February.
Embodiment 3
Rhizoma Chuanxiong 20 grams, Radix Bupleuri 10 grams, Radix Polygalae 12 grams, Radix Angelicae Sinensis 20 grams, the Radix Paeoniae Alba 30 grams, Radix Curcumae 10 grams, Flos Carthami 10 grams, Semen Platycladi 15 grams and the common grinding and processing of Semen Ziziphi Spinosae (parched) 50 grams are become fine powder, cross 100 orders with top sieve, mix homogeneously, ozone sterilization 20 minutes, add 177 gram Mel, mix well, make capsule routinely, every capsules is adorned 0.3 gram.One day 3 times, each 2-3 grain, warm water delivery service, be a course of treatment February.
Embodiment 4
Rhizoma Chuanxiong 16 grams, Radix Bupleuri 8 grams, Radix Polygalae 14 grams, Radix Angelicae Sinensis 15 grams, the Radix Paeoniae Alba 12 grams, Radix Curcumae 13 grams, Flos Carthami 18 grams, Semen Platycladi 18 grams and the common grinding and processing of Semen Ziziphi Spinosae (parched) 45 grams are become fine powder, cross 100 orders with top sieve, mix homogeneously, ozone sterilization 20 minutes, adding 159 gram Mel mixes well, make capsule routinely, every capsules is adorned 0.3 gram.One day 3 times, each 2-3 grain, warm water delivery service, be a course of treatment February.
Claims (1)
1. a Chinese patent medicine preparation for the treatment of depression after cerebral infarction is characterized in that: be made up of following Chinese medicine raw materials by weight proportion: Rhizoma Chuanxiong 10-20, Radix Bupleuri 6-10, Radix Polygalae 6-15, Radix Angelicae Sinensis 10-20, Radix Paeoniae Alba 10-30, Radix Curcumae 10-15, Flos Carthami 10-20, Semen Platycladi 15-25 and Semen Ziziphi Spinosae (parched) 30-50.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008100147443A CN101249246B (en) | 2008-03-13 | 2008-03-13 | Proprietary Chinese medicine preparations for curing depression after cerebral infarction |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008100147443A CN101249246B (en) | 2008-03-13 | 2008-03-13 | Proprietary Chinese medicine preparations for curing depression after cerebral infarction |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101249246A CN101249246A (en) | 2008-08-27 |
| CN101249246B true CN101249246B (en) | 2010-09-29 |
Family
ID=39952956
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2008100147443A Expired - Fee Related CN101249246B (en) | 2008-03-13 | 2008-03-13 | Proprietary Chinese medicine preparations for curing depression after cerebral infarction |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101249246B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102198253B (en) * | 2011-05-27 | 2012-09-05 | 上海市中医医院 | Traditional Chinese medicine composition for resisting depression, and preparation method as well as application thereof |
| CN105147947A (en) * | 2015-09-30 | 2015-12-16 | 郑梅 | Traditional Chinese medicine composition preventing cerebral infarction and preparing method |
| CN105663961A (en) * | 2016-02-18 | 2016-06-15 | 高思山 | Traditional Chinese medicine for treating deprementia of liver and kidney deficiency type cerebral infarction patients and preparing method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1626154A (en) * | 2003-12-12 | 2005-06-15 | 郭浩山 | Method for preparing liquid for sleep peacefully and relieving restlessness |
| CN1994451A (en) * | 2006-12-27 | 2007-07-11 | 河南太龙药业股份有限公司 | Chinese medicinal composition for treating depression, its preparation method and application |
-
2008
- 2008-03-13 CN CN2008100147443A patent/CN101249246B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1626154A (en) * | 2003-12-12 | 2005-06-15 | 郭浩山 | Method for preparing liquid for sleep peacefully and relieving restlessness |
| CN1994451A (en) * | 2006-12-27 | 2007-07-11 | 河南太龙药业股份有限公司 | Chinese medicinal composition for treating depression, its preparation method and application |
Non-Patent Citations (4)
| Title |
|---|
| 李泉红等.中风后抑郁中医药治疗进展.中医药信息22 1.2005,22(1),8-11. |
| 李泉红等.中风后抑郁中医药治疗进展.中医药信息22 1.2005,22(1),8-11. * |
| 邓国鹏等.自拟通脑清心汤治疗脑卒中后抑郁失眠28例.贵阳中医学院学报28 1.2006,28(1),26-27. |
| 邓国鹏等.自拟通脑清心汤治疗脑卒中后抑郁失眠28例.贵阳中医学院学报28 1.2006,28(1),26-27. * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101249246A (en) | 2008-08-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1051237C (en) | Meicinal prepn. "Kexianling" for curing epilepsy | |
| CN100460008C (en) | Chinese medicine composition for treating cancer | |
| CN101711847B (en) | Oral traditional Chinese medicine preparation for treating melancholia and anxiety neurosis | |
| CN102631579B (en) | Oral Chinese herbal preparation for treating post-traumatic brain syndrome | |
| CN101829274B (en) | Medicament for treating liver disease | |
| CN102872376B (en) | Traditional Chinese medicine composition for nursing or treating diabetic peripheral neuropathy pain | |
| CN101249246B (en) | Proprietary Chinese medicine preparations for curing depression after cerebral infarction | |
| CN1263503C (en) | 'Changyuan' capsule and preparing techniue | |
| CN101417033B (en) | Traditional Chinese medicine for treating insomnia | |
| CN102274405A (en) | Medicament for treating sequelae of cerebral concussion | |
| CN1324650A (en) | Effective medicine for treating cervical vertebra disease as one kind of intractable disease | |
| CN104758652A (en) | Traditional Chinese medicine composition for treating dizziness | |
| CN1518995A (en) | Medication for anti senile dementia as well as preparation method usage | |
| CN1814163A (en) | Chinese medicine for treating cardiovascular and cerebrovascular trrombus and preparing method | |
| CN103386080B (en) | Medicine composite for curing combined external head injuries in clinical nursing | |
| CN1055238C (en) | Calming and desadening pill preparing process thereof | |
| CN110841007B (en) | Traditional Chinese medicine composition for treating cerebral apoplexy sequela and application thereof | |
| CN102247551A (en) | Medicament for treating constipation | |
| CN1183921C (en) | Medicine for treating depression via head acupoint osmosis | |
| CN102198240B (en) | Medicament for treating headache | |
| CN101502597A (en) | Medicament for treating stomachache and preparation method thereof | |
| CN1056308C (en) | Medicine for adjusting cranial nerve function | |
| CN1183920C (en) | Medicine for treating neurosis via head acupoint osmosis | |
| CN101843768B (en) | Chinese medicament for treating climacteric syndromes | |
| CN1232296C (en) | Chinese herbal medicine preparation for treating bone and muscle injuries |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20100929 Termination date: 20110313 |