CN101244227B - Chinese medicine pill mainly for treating nephropathy - Google Patents

Abstract

The invention discloses a traditional Chinese medicine pill mainly for curing nephropathy and a preparation method; the medicine pill is prepared with the following materials at a certain part by weight, poison nut 3 to 5, muskiness 3 to 5, camphor 3 to 5, borneol 3 to 5, toad 3 to 5, aweto 3 to 5, plantain seed 12 to 30, red peony root 12 to 30, polyporus 12 to 30, figwort 12 to 30, Paris polyphylla 12 to 30, rhizome ligustici wallichii 12 to 30, Chinese rhubarb 12 to 30, betel-nut 12 to 30, fried foxnut 12 to 30, Cherokee rose 12 to 30, Rhizoma Zedoariae 12 to 30, false wintergreen 12 to 30, arrow worms 12 to 30, safflower 12 to 30, white mustard seed 12 to 30, baked Squama Manitis 12 to 30. The medicine pill has the positive effects of quick curative effect, fast effects, taking effectwithin 2 to 7 days, safety and reliability, no toxic or side effect; the invention brings about no toxicity or allergic reaction in a clinical use of 32 years. The invention is economical and convenient, with an accurate curative effect.

Description

A kind of Chinese medicine pill for the treatment of nephropathy

(1) technical field

The present invention discloses a kind of pill by Chinese herbal medicine preparation, particularly mainly treats the pill its preparation method that is prepared into by Chinese herbal medicine of nephropathy.

(2) background technology

Nephropathy mainly is to be the disease of outward manifestation with the edema.Because the intravital water retention of body spreads unchecked skin, causes women's head-ornaments, eyelid, extremity, abdomen back even anasarca, serious also can be with hydrothorax, ascites etc.The traditional Chinese medical science as " Ling Shu Miraculous Pivot or Divine Axis watery distension " piece of writing to the description of edema: " water begin also, and the order nest is little swollen, as the shape that has newly crouched, its notable and rashing pulsation of common carotid artery, in time, coughed, cold over the region between the genitalia and thigh, puffiness of the legs, abdomen are that its water becomes greatly." " element is asked the negative and positive another matter " piece of writing and for example: " three constipation of YIN types meanings water is also." three the moon are meant the lunar lung spleen channel of brothers, explanation be edema and lung spleen for sick, and be difficult to transmit the crystal, regulating fluid apssage is relevant.Doctor trained in Western medicine is to sending out the meaning glomerulonephritis at the beginning of the nephropathy, behind pharyngeal again discomfort or other position furuncle, sensitization source and the hemolytic streptococcal infection, the glomerule catarrhal inflammation sexually revises or by middle lower urinary tract infection superinverse inflammatory lesions takes place to positions such as renal pelvis.One shows albuminuria, edema, hypertension three big features for this disease in the world, and with antiinflammatory, antiallergic is avoided salt, and diuresis etc. be its main Therapeutic Method, and often with the passing of time delay is difficult to rehabilitation, and inactive then being easy to of hormone recurred.Because hormone side effect is big, often causes serious adverse consequences, as osteoporosis, femur head necrosis etc.The nephropathy later stage, life quality was poor, often causes the situation of losing both a person and money because renal failure or uremia need to survive the time by abdominal part dialysis or hemodialysis, and its treatment cost is big.Again because medical expense height, the much clear-cut abandoning cure of patient.

(3) summary of the invention

The objective of the invention is to overcome the expense height that existing treatment nephropathy exists, defectives such as weak curative effect provide a kind of Chinese medicine for oral administration ball for the treatment of nephropathy.

For realizing purpose of the present invention, existing according to following technical scheme.This pill is made by following materials based on weight: vomiting nut 3-5, Moschus 3-5, Camphora 3-5, Borneolum Syntheticum 3-5, Bufo siccus 3-5, Cordyceps 3-5, Semen Plantaginis 12-30, Radix Paeoniae Rubra 12-30, Polyporus 12-30, Herba Wedeliae Wallichii 12-30, Rhizoma Paridis 12-30, Rhizoma Chuanxiong 12-30, Radix Et Rhizoma Rhei 12-30, Semen Arecae 12-30, Semen Euryales (parched) 12-30, Fructus Rosae Laevigatae 12-30, Rhizoma Curcumae 12-30, Herba Pyrolae 12-30, Ramulus Euonymi 12-30, Stigma Croci 12-30, Semen Sinapis Albae 12-30, stir-baked SQUAMA MANITIS 12-30.

The preparation method of this pill is as described below:

Step 1: vomiting nut is gone in the mung bean water after the well-done peeling, put into Semen Tritici aestivi powder medicated porridge and soak, changed medicated porridge 1 time in 1 day, pull clear water after 7 days like this out and clean, it is chopped up dry;

Step 2:, put into water then and soak with Radix Paeoniae Rubra, Polyporus, Herba Wedeliae Wallichii, Rhizoma Paridis, Rhizoma Chuanxiong, Radix Et Rhizoma Rhei, Semen Arecae, Rhizoma Curcumae, Herba Pyrolae, Ramulus Euonymi 10 flavor Chinese medicine sections;

Step 3: the step 2 soak is added Stigma Croci, Semen Sinapis Albae, stir-baked SQUAMA MANITIS, Semen Plantaginis, Semen Euryales (parched), Fructus Rosae Laevigatae, and the remittance pot is interior with several minutes at a simmer, filter and remove residue, it is standby that medicinal liquid is store; Then medicinal residues are added water and fry in shallow oil again, several times so repeatedly, the gained medicinal liquid is converged, put into pot and fry in shallow oil a few hours slowly, and constantly stir with little fire, prevent to be burned, standby until the semisolid mastic of simmer down to;

Step 4: resulting mastic in the step 3 is placed in the container, add the Mel dissolving; Vomiting nut, Moschus, Camphora, Borneolum Syntheticum, Bufo siccus, the Cordyceps that will be ground into fine powder more add described container for stirring and evenly make honeyed pill, about 0.3 gram of every ball.

Good effect of the present invention is:

1. curative effect is rapid, and instant effect is taken medicine and can be taken effect in 2-7 days.

2. safe and reliable, have no side effect, this Chinese medicine for oral administration ball is no any toxicity and allergic phenomena in the period of clinical use 32.

3. economical and convenient, determined curative effect.

Prescription pharmacology of the present invention is according to being: Semen Arecae, Semen Plantaginis, the circulation of qi promoting of Polyporus removing food stagnancy are with diuretic; Stigma Croci, Rhizoma Curcumae, Rhizoma Chuanxiong, Radix Paeoniae Rubra promoting blood circulation to remove blood stasis knot tonneau passages through which vital energy circulates; Cordyceps, Semen Euryales lung benefiting kidney controlling nocturnal emission with astringent drugs, spleen reinforcing are dried; The secret gas of Fructus Rosae Laevigatae controlling nocturnal emission with astringent drugs; The Squama Manis detumescence of assaulting fortified position of stimulating the menstrual flow; Rhizoma Paridis, Radix Et Rhizoma Rhei heat-clearing and toxic substances removing, the detumescenceization blood stasis; Borneolum Syntheticum, Camphora, Bufo siccus heat clearing away are anticorrosion, and removing toxic substances and promoting subsidence of swelling is turbid to go; The then warm Tonghua of Semen Sinapis Albae expectorant with system medicine-feeding heat clearing away too; The vomiting nut eliminating stagnation of stimulating the menstrual flow, subduing swelling and relieving pain; Herba Pyrolae, Ramulus Euonymi tool tonifying the lung kidney, the merit that eliminating toxic substances to remove stasis is turbid; Have one's ideas straightened out relieving pain and activating blood circulation hemostasis of Moschus, removing the necrotic tissue is held back and is injurious to life newly to help the effect of all medicines.

This Chinese medicine pill of clinical discovery also has curative effect preferably to urinary system calculus, hydroureter etc.

Function of the present invention is that Saporoshje is harnessed the river---spleen invigorating wins wet; Building up the spleen to supplement the lung---regulating fluid apssage; Prolonged illness must be empty, and the many stasis of bloods one of prolonged illness are held concurrently and blood circulation promoting and blood stasis dispelling hard masses softening and resolving with the gas that reinforces the kidney.Cure mainly: acute and chronic glomerulonephritis, pyelonephritis, kidney, hydroureter, chronic kidney hypofunction are to uremia, the nephrotic syndrome etc.

(4) specific embodiment

Embodiment 1: Semen Plantaginis 12 grams, Radix Paeoniae Rubra 12 grams, Polyporus 12 grams, Herba Wedeliae Wallichii 12 grams, Rhizoma Paridis 12 grams, Rhizoma Chuanxiong 12 grams, Radix Et Rhizoma Rhei 12 grams, Semen Arecae 12 grams, Semen Euryales (parched) 12 grams, Fructus Rosae Laevigatae 12 grams, Rhizoma Curcumae 12 grams, Herba Pyrolae 12 grams, Ramulus Euonymi 12 grams, Stigma Croci 12 grams, Semen Sinapis Albae 12 grams, stir-baked SQUAMA MANITIS 12 grams, vomiting nut 3 grams, Moschus 3 grams, Camphora 3 grams, Borneolum Syntheticum 3 grams, Bufo siccus 3 grams, Cordyceps 3 grams.

The preparation technology of this pill is as follows:

Step 1: the vomiting nut of above-mentioned weight is gone in the mung bean water after the well-done peeling, put into Semen Tritici aestivi powder medicated porridge and soak, changed medicated porridge 1 time in 1 day, pull clear water after 7 days like this out and clean, it is chopped up dry.

Step 2:, put into water 3000ml then and soaked 2-3 hour with Radix Paeoniae Rubra, Polyporus, Herba Wedeliae Wallichii, Rhizoma Paridis, Rhizoma Chuanxiong, Radix Et Rhizoma Rhei, Semen Arecae, Rhizoma Curcumae, Herba Pyrolae, the Ramulus Euonymi 10 flavor Chinese medicine sections of above-mentioned weight.

Step 3: the step 2 soak is added Stigma Croci, Semen Sinapis Albae, stir-baked SQUAMA MANITIS, Semen Plantaginis, Semen Euryales (parched), the Fructus Rosae Laevigatae of above-mentioned weight, and import in the pot with at a simmer it, fried in shallow oil 30-60 minute, filter and remove residue, standby with medicinal liquid storage adds water with medicinal residues then and fries in shallow oil, 3 times so repeatedly, the gained medicinal liquid is merged in a bite pot, slowly fried in shallow oil 3-5 hour with little fire, and constantly stir, prevent to be burned, until simmer down to semi-solid mastic, standby.

Step 4: the ointment that step 3 is made places and adds the Mel dissolving in the container, puts into the vomiting nut, Moschus, Camphora, Borneolum Syntheticum, Bufo siccus, the Cordyceps that are ground into fine powder again and stirs and make honeyed pill, every ball about 0.3

Embodiment 2: Semen Plantaginis, Radix Paeoniae Rubra, Polyporus, Herba Wedeliae Wallichii, Rhizoma Paridis, Rhizoma Chuanxiong, Radix Et Rhizoma Rhei, Semen Arecae, Semen Euryales (parched), Fructus Rosae Laevigatae, Rhizoma Curcumae, Herba Pyrolae, Ramulus Euonymi, Stigma Croci, Semen Sinapis Albae, stir-baked SQUAMA MANITIS, more than 16 the flavor medicines respectively be 30 the gram.Vomiting nut, Moschus, Camphora, Borneolum Syntheticum, Bufo siccus, Cordyceps 6 flavor medicines respectively are 5 grams.

Preparation technology such as embodiment 1.

When using medicine of the present invention 3 times on the 1st.Body weight 15kg is following to use 0.15g, uses 0.3g more than the body weight 15kg.

Use patient of the present invention to derive from (1) outpatient service prescription on individual diagnosis person, (2) are from the person of changing the place of examination of other hospital.

Recovery from illness standard and curative effect: treatment 1006 routine acute and chronic glomerulonephritiies, pyelonephritis, hydronephrosis, chronic kidney hypofunction are to uremic case, wherein in 32 years of in May, 1975-2007 year May:

Recovery from illness, promptly clinical symptoms all disappears, and lab testing does not have positive index, and 837 examples are arranged, and accounts for 83.20%.

Take a turn for the better, i.e. clinical symptom disappearance, the lab testing routine urinalysis: erythrocyte, leukocyte feminine gender, protein positive, renal function is normal, and 129 examples are arranged, and accounts for 12.82%.

Invalid: promptly clinical symptoms and lab testing all do not have change, and 40 examples are arranged, and account for 3.98%.

Clinical total effective rate is: 96.02%.

Case 1: Song, man, 19 years old, Yulin, Xuchang County township Da Song people from village.JIUYUE in 2000 is gone to a doctor the morning on the 18th.

Main suit: find glomerulonephritis 2 months.The patient before February no obvious inducement the puffiness of the eyes appears, be carrying out property and increase the weight of, cure February in nonlocal nephropathy section hospital, its effect is not good, the first quarter moon amount of urine reduces gradually, so far 2 days anurias.Have a medical check-up: mind is asked, and spirit is poor, blood pressure: 144/93mmHg, and anemic face, anasarca, heart rate: 103/ minute, rate was neat, and pulmonary (-) does not reach under the liver spleen rib, and ascites is obvious, and it is positive that the kidney district kowtows pain, pale tongue, tongue is greasy in vain.B ultrasonic shows: two kidneys, hydroureter, the kidney volume-diminished is obvious with right kidney.Routine blood test: WBC:9.4 * 10 ⁹/ L, hemoglobin: 89g/L.Kidney merit: blood urea nitrogen: 23.7mmol/L, creatinine: 505umol/L, uric acid: 27.7mmol/L.

Treatment: promptly give the oral 0.4g of above-mentioned Chinese medicine pill, and 6 o'clock urine is logical certainly between supper.Because of effectively, continue clothes medicine-feeding 4 months, recover.

Case 2: Zhao, the man, 45 years old, the peasant, Xiangcheng County Fan Hu township Zhu Yuan people from village, go to a doctor July 4 nineteen eighty-two.

Main suit: find to suffer from chronic nephritis 9 years.The patient found chronic nephritis before 9 years, Drug therapy always, certain city institute of traditional Chinese medicine treatment 28 days is lived in acute attack in the recent period, curative effect is not good enough and the renal failure that becomes, day about 100ml of voided volume, because of body constitution severe weak in institute's arrangement funeral affairs.Have a medical check-up: women's head-ornaments extremity edema companion ascites pleural fluid, pale complexion, mind is dispirited, lateral position, face is other to be put in the Cans interface slowly from the saliva that goes out.Blood pressure 190/104mmHg, routine urinalysis: albumen (++ ++), erythrocyte (++), granule tubular (++), pyocyte (++).Thready and weak pulse, the big matter of corpulent tongue is light, thick and greasy fur.

Treatment: throw the conventional dosing 0.3g of this pill, oral 3/ day.Patient day's voided volume is by increasing to 2200ml after 4 days, receives liquid diet 1500ml day, and ascites pleural fluid disappears after 10 days, blood pressure 136/76mmHg; Routine urinalysis: albumen (++), erythrocyte (+), pyocyte (+).The recovery from illness in 2 months of taking medicine.Follow up a case by regular visits to not recurrence so far.

Case 3: Jiang, man 27 years old, the peasant, Xiangcheng County Jiang Zhuan township Jiang Zhuan people from village, on July 21st, 1981 went to a doctor.

The main suit: patient suffered from chronic nephritis 5 years, increased the weight of first quarter moon.Patient suffered from chronic nephritis 5 years, lived in certain the People's Hospital, city before the first quarter moon, though through with all strength treatment, the patient's condition is not good day by day, and enlarged abdomen such as drum are transferred from one hospital to another and made still DeGrain of dialysis therapy 1 time, and family members fear it extremely in hospital, and coffin is got ready, and existing anxious leaving hospital returns.

Have a medical check-up: patient's apathetic expression, skin is grey black, the swollen edema over the face of limb especially with ascites for very, a little less than the soft pulse.Then throw the conventional dosing 0.3g of this pill, oral 3/ day.To urine amount on the 2nd by increasing, mind is gradually clear.Routine urinalysis on the 5th: albumen (++ ++), tubular (+++), pyocyte (+++), erythrocyte (+).Take medicine to ascites disappearance on the 16th, only instep and eyelid have swollen the elephant slightly.Urine test: albumen (+++), pyocyte (+).Continue to take medicine-feeding 9 months and heal.With recurrence extremely so far.

Case 4: journey, the man, 20 years old, the student, Luohe City people from Wuyang County, December was gone to a doctor on the 4th in 2006.

Main suit: eyelid and edema of pair of lower extremities March.The patient puffiness of the eyes occurred after " flu " before March, two lower limb refer to sunken property edema, do not do treatment at that time, be diagnosed as nephritis at local examination in hospital before February, hospitalization poor effect in February, the urine amount is gradually reduced to 200ml/ day, leave hospital because of financial difficulties, satisfy and go to a doctor.Have a medical check-up: blood pressure 180/108mmHg, pale complexion, mind is dispirited, the puffiness of the eyes, the voiced sound positive is moved in the abdominal part percussion, and edema of pair of lower extremities is and refers to fall into property.Routine urinalysis: albumen (+++), erythrocyte (+), granule tubular (+++), pyocyte (++).Thready pulse is heavy, and the big matter of corpulent tongue is light, and tongue is greasy in vain.

Treatment: throw the conventional dosing 0.3g of this pill, oral 3/ day.Patient day's voided volume pursues and increases to 2600ml after 5 days, but anorexia amount liquid diet, and edema of lower limbs disappears after 15 days, blood pressure 132/74mmHg; Routine urinalysis: albumen (+), erythrocyte (±), pyocyte (±).The recovery from illness in 2 months of taking medicine.Follow up a case by regular visits to not recurrence so far.

Claims (1)

1. a Chinese medicine pill for the treatment of nephropathy is characterized in that being made by following materials based on weight: vomiting nut 3-5, Moschus 3-5, Camphora 3-5, Borneolum Syntheticum 3-5, Bufo siccus 3-5, Cordyceps 3-5, Semen Plantaginis 12-30, Radix Paeoniae Rubra 12-30, Polyporus 12-30, Herba Wedeliae Wallichii 12-30, Rhizoma Paridis 12-30, Rhizoma Chuanxiong 12-30, Radix Et Rhizoma Rhei 12-30, Semen Arecae 12-30, Semen Euryales (parched) 12-30, Fructus Rosae Laevigatae 12-30, Rhizoma Curcumae 12-30, Herba Pyrolae 12-30, Ramulus Euonymi 12-30, Stigma Croci 12-30, Semen Sinapis Albae 12-30, stir-baked SQUAMA MANITIS 12-30;

The preparation method of this pill is as described below:

Step 1: vomiting nut is gone in the mung bean water after the well-done peeling, put into Semen Tritici aestivi powder medicated porridge and soak, changed medicated porridge 1 time in 1 day, pull clear water after 7 days like this out and clean, it is chopped up dry;

Step 2:, put into water then and soak with Radix Paeoniae Rubra, Polyporus, Herba Wedeliae Wallichii, Rhizoma Paridis, Rhizoma Chuanxiong, Radix Et Rhizoma Rhei, Semen Arecae, Rhizoma Curcumae, Herba Pyrolae, Ramulus Euonymi 10 flavor Chinese medicine sections;

Step 3: the step 2 soak is added Stigma Croci, Semen Sinapis Albae, stir-baked SQUAMA MANITIS, Semen Plantaginis, Semen Euryales (parched), Fructus Rosae Laevigatae, and the remittance pot is interior with several minutes at a simmer, filter and remove residue, it is standby that medicinal liquid is store; Then medicinal residues are added water and fry in shallow oil again, several times so repeatedly, the gained medicinal liquid is converged, put into pot and fry in shallow oil a few hours slowly, and constantly stir with little fire, prevent to be burned, standby until the semisolid mastic of simmer down to;

Step 4: resulting mastic in the step 3 is placed in the container, add the Mel dissolving; Vomiting nut, Moschus, Camphora, Borneolum Syntheticum, Bufo siccus, the Cordyceps that will be ground into fine powder more add described container for stirring and evenly make honeyed pill, about 0.3 gram of every ball.