CN101244114A - Composition for improving and treating gastrointestinal tract indigestion symptom - Google Patents
Composition for improving and treating gastrointestinal tract indigestion symptom Download PDFInfo
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- CN101244114A CN101244114A CNA2008100080180A CN200810008018A CN101244114A CN 101244114 A CN101244114 A CN 101244114A CN A2008100080180 A CNA2008100080180 A CN A2008100080180A CN 200810008018 A CN200810008018 A CN 200810008018A CN 101244114 A CN101244114 A CN 101244114A
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- gastrointestinal tract
- indigestion symptom
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- composition
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention relates to a composition for improving and curing gastrointestinal indigestion symptom, which mainly comprises L-glutamine, aldioxa, liquorice, cinnamon, radish, sodium bicarbonate, sodium bicarbonate, magnesium carbonate, precipitated calcium carbonate, magnesium aluminium orthosilicate, henbane extracts, complex enzyme, jejuni protease and lipase. Proper additives can be added in the composition to make oral preparation with different forms, such as granules, tablets and capsules.
Description
Technical field
The present invention relates to a kind of effective improvement and the compositions for the treatment of gastrointestinal tract indigestion symptom.
Background technology
With gastric acid and the activatory antacid of inhibition pepsin, this was well-known during the stomach medication all contained mostly in the market.Yet all wish can be rapidly in and gastric acid the time, can have more lasting and lasting in the function of gastric acid.This compositions just can be improved this situation, adds the reparation that gastric mucosa repairing agent effectively helps gastric mucosa simultaneously, adds the crude drug that is good for the stomach and can improve and promote appetite, adds the digestion that digestive pharmaceutical can promote gastric content.
L-glutaminate in this product can impel gastric mucosa regeneration; Aldioxa can promote mucous secretion, thereby repairs gastric mucosa; The Radix Glycyrrhizae powder can prevent that gastric mucosal blood flow is low excessively, further helps to repair gastric mucosa.Situations such as Radix Dauci Sativae energy improving appetite is depressed; The fragrance of Cortex cinnamomi japonici (Ramulus Cinnamomi) then can promote appetite.Sodium bicarbonate, magnesium carbonate, precipitated calcium carbonate three can be rapidly in and gastric acid, relax unhappy symptoms such as heartburn, belch; Magnesiumaluminumsilicate or orthosilicic acid magnalium routinely in and gastric acid, the protection gastric mucosa; Hyoscyamus extract has the effect that suppresses gastric secretion, can make with the antacid combination in and the gastric acid effect more lasting.Complex digestive enzyme, aspergillus protease, lipase can promote digestion, the emptying of gastric content to improve flatulence as digestive pharmaceutical.
Summary of the invention
The present invention aims to provide a kind of can effectively the improvement and the compositions for the treatment of gastrointestinal tract indigestion symptom.
This product key component comprises gastric mucosa repairing agent, gastrotonica, antacid, digestive pharmaceutical and additive.Gastric mucosa repairing agent can select L-glutaminate, aldioxa (Aldioxa), red bud cypress, Rhizoma Corydalis, Radix Glycyrrhizae, Radix Glycyrrhizae to get in thing, glycyrrhizic acid and its esters, histidine monohydrochloride, copper pheophytin potassium, sodium copper chlorophyllin, cetraxate hydrochloride, the Gaster Sus domestica mucosa protease extract one or more; Gastrotonica can be selected one or more in Foeniculum vulgare, Aloe, Fructus Foeniculi, Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix Dauci Sativae, Rhizoma Curcumae Longae, scutellariae,radix, Rhizoma Coptidis, Pericarpium Zanthoxyli, Radix Ginseng, Oleum Caryophylli, Semen Myristicae, Flos Caryophylli, Herba Menthae, Oleum menthae, the Oleum Anisi Stellati; Antacid can be selected one or more in sodium bicarbonate, magnesium carbonate, precipitated calcium carbonate, sedimentation magnesium carbonate, orthosilicic acid magnalium, hyoscyamus extract, glycine, hydrotalcite, the magnesium hydroxide; Digestive pharmaceutical can be selected one or more in complex digestive enzyme (comprise diastase, gelatinized corn starch refine enzyme, proteopepsis enzyme, saccharification of cellulose enzyme), aspergillus protease, lipase, dehydrocholic acid, bile extract, cholic acid, the bile powder; Additive can comprise excipient, disintegrating agent, correctives, binding agent, lubricant.
Wherein the additive excipient can be selected one or more in lactose, starch, crystalline cellulose, sucrose, the mannitol; Correctives can be selected one or more in aspartame, steviosin, mannitol, sucrose, fructose, xylitol, 1-menthol, Oleum menthae, aromatic, the spice; Disintegrating agent can be selected one or more in hydroxypropyl cellulose, carboxymethyl starch sodium, microcrystalline Cellulose, the carboxymethylcellulose calcium; Binding agent can be selected one or more in water, ethanol, hydroxypropyl cellulose, hydroxypropyl methylcellulose, polyvinylpyrrolidone, starch slurry, rubber cement, the carbomer; Lubricant can be selected magnesium stearate, calcium stearate, Pulvis Talci, micropowder silica gel, hydrogenated vegetable oil.
The dosage form of this product can be granule, sheet, capsule.
This product mainly contains following effect: can effectively improve with treat that drink, regurgitation (nauseating, stomach is nauseating, the drunk vomiting that causes, nauseating), vomiting, stomach discomfort, surfeit, dyspepsia, facilitating digestion, inappetence (loss of appetite), stomach function are weak, heartburn, stomachache, hyperchlorhydria, belch, flatulence, uncomfortable in chest, stomach abdominal part sensation of fullness.
The specific embodiment
Below in conjunction with embodiment the present invention is described in further detail, but should understands the scope that scope of the present invention is not limited only to these embodiment.
Embodiment 1 granule
Component recipe quantity (g)
L-glutaminate 135
Aldioxa 50
Radix Glycyrrhizae 75
Cortex cinnamomi japonici (Ramulus Cinnamomi) 145
Radix Dauci Sativae 75
Sodium bicarbonate 600
Magnesium carbonate 150
Precipitated calcium carbonate 80
Orthosilicic acid magnalium 80
Hyoscyamus extract 10
Complex digestive enzyme 2,000 30
Aspergillus protease 65
Lipase A P6 20
Mannitol 160
Hydroxypropyl cellulose 50
L-menthol 0.7
Oleum menthae 1
70% alcoholic solution is an amount of
Make 1000 bags
Preparation method:
(1). become fine powder to cross 100 mesh sieves the supplementary material pulverize separately and weigh standby;
(2). take by weighing the supplementary material mix homogeneously that crushes by recipe quantity;
(3). prepare soft material with 70% alcoholic solution, 18 mesh sieves are granulated, dried;
(4). after the dried, with 12 eye mesh screen granulate;
(5). through being up to the standards, be packaged into bag, promptly.
Embodiment 2 granules
Component recipe quantity (g)
L-glutaminate 120
Aldioxa 45
Radix Glycyrrhizae 70
Cortex cinnamomi japonici (Ramulus Cinnamomi) 125
Radix Dauci Sativae 55
Sodium bicarbonate 600
Magnesium carbonate 150
Precipitated calcium carbonate 80
Orthosilicic acid magnalium 80
Hyoscyamus extract 10
Complex digestive enzyme 2,000 30
Aspergillus protease 65
Lipase A P6 20
Mannitol 140
Hydroxypropyl cellulose 40
L-menthol 0.5
70% alcoholic solution is an amount of
Make 1000 bags
Preparation method:
(1). become fine powder to cross 100 mesh sieves the supplementary material pulverize separately and weigh standby;
(2). take by weighing the supplementary material mix homogeneously that crushes by recipe quantity;
(3). prepare soft material with 70% alcoholic solution, 18 mesh sieves are granulated, dried;
(4). after the dried, with 12 eye mesh screen granulate;
(5). through being up to the standards, be packaged into bag, promptly.
Embodiment 3 tablets
Component recipe quantity (g)
L-glutaminate 135
Aldioxa 50
Radix Glycyrrhizae 75
Cortex cinnamomi japonici (Ramulus Cinnamomi) 145
Radix Dauci Sativae 75
Sodium bicarbonate 600
Magnesium carbonate 150
Precipitated calcium carbonate 80
Orthosilicic acid magnalium 80
Hyoscyamus extract 10
Complex digestive enzyme 2,000 30
Aspergillus protease 65
Lipase A P6 20
Mannitol 100
Hydroxypropyl cellulose 30
L-menthol 0.7
Oleum menthae 1
Magnesium stearate 5
5%PVP solution is an amount of
Make 3000
Preparation method:
(1). become fine powder to cross 100 mesh sieves the supplementary material pulverize separately and weigh standby;
(2). take by weighing the supplementary material mix homogeneously that crushes by recipe quantity;
(3). with 5%PVP formulations prepared from solutions soft material, 20 mesh sieves are granulated, dried;
(4). after the dried, with 18 eye mesh screen granulate;
(5). take by weighing above formula ratio magnesium stearate and the abundant mixing of dried granule;
(6). through being up to the standards tabletting, packing.
Embodiment 4 capsules
Component recipe quantity (g)
L-glutaminate 135
Aldioxa 50
Radix Glycyrrhizae 75
Cortex cinnamomi japonici (Ramulus Cinnamomi) 145
Radix Dauci Sativae 75
Sodium bicarbonate 600
Magnesium carbonate 150
Precipitated calcium carbonate 80
Orthosilicic acid magnalium 80
Hyoscyamus extract 10
Complex digestive enzyme 2,000 30
Aspergillus protease 65
Lipase A P6 20
Lactose 90
Hydroxypropyl cellulose 30
L-menthol 0.7
Oleum menthae 1
Magnesium stearate 5
70% alcoholic solution is an amount of
Make 3000
Preparation method:
(1). become fine powder to cross 100 mesh sieves the supplementary material pulverize separately and weigh standby;
(2). take by weighing the supplementary material mix homogeneously that crushes by recipe quantity;
(3). prepare soft material with 70% alcoholic solution, 20 mesh sieves are granulated, dried;
(4). after the dried, with 18 eye mesh screen granulate;
(5). take by weighing above formula ratio magnesium stearate and the abundant mixing of dried granule;
(6). through being up to the standards, encapsulated.
Claims (4)
1. the compositions of an improvement and treatment gastrointestinal tract indigestion symptom is characterized in that: contain the optional L-glutaminate of gastric mucosa repairing agent, aldioxa (Aldioxa), Radix Glycyrrhizae one or more.
2. the compositions of an improvement and treatment gastrointestinal tract indigestion symptom is characterized in that: contain in the optional Cortex cinnamomi japonici (Ramulus Cinnamomi) of gastrotonica, the Radix Dauci Sativae one or both.
3. the compositions of an improvement and treatment gastrointestinal tract indigestion symptom is characterized in that: contain in the optional sodium bicarbonate of antacid, magnesium carbonate, precipitated calcium carbonate, Magnesiumaluminumsilicate, orthosilicic acid magnalium, the hyoscyamus extract one or more.
4. the compositions of an improvement and treatment gastrointestinal tract indigestion symptom is characterized in that: contain the optional complex digestive enzyme of digestive pharmaceutical, aspergillus protease, lipase one or more.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008100080180A CN101244114A (en) | 2008-03-04 | 2008-03-04 | Composition for improving and treating gastrointestinal tract indigestion symptom |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008100080180A CN101244114A (en) | 2008-03-04 | 2008-03-04 | Composition for improving and treating gastrointestinal tract indigestion symptom |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101244114A true CN101244114A (en) | 2008-08-20 |
Family
ID=39944934
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2008100080180A Pending CN101244114A (en) | 2008-03-04 | 2008-03-04 | Composition for improving and treating gastrointestinal tract indigestion symptom |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101244114A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102512402A (en) * | 2011-12-21 | 2012-06-27 | 无锡济民可信山禾药业股份有限公司 | Novel preparation of medicine for treating gastric and duodenal ulcers and preparation method thereof |
| CN104083515A (en) * | 2014-06-30 | 2014-10-08 | 咸洪震 | Traditional Chinese medicine preparation for treating functional dyspepsia and preparation method of traditional Chinese medicine preparation |
| CN112274612A (en) * | 2019-09-17 | 2021-01-29 | 纽新宝药业有限公司 | Composition, use and medicament thereof |
-
2008
- 2008-03-04 CN CNA2008100080180A patent/CN101244114A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102512402A (en) * | 2011-12-21 | 2012-06-27 | 无锡济民可信山禾药业股份有限公司 | Novel preparation of medicine for treating gastric and duodenal ulcers and preparation method thereof |
| CN104083515A (en) * | 2014-06-30 | 2014-10-08 | 咸洪震 | Traditional Chinese medicine preparation for treating functional dyspepsia and preparation method of traditional Chinese medicine preparation |
| CN104083515B (en) * | 2014-06-30 | 2016-08-17 | 咸洪震 | Chinese medicine preparation for the treatment of functional dyspepsia FD and preparation method thereof |
| CN112274612A (en) * | 2019-09-17 | 2021-01-29 | 纽新宝药业有限公司 | Composition, use and medicament thereof |
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| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20080820 |