CN101218478B - Refrigerator for storing vials and cartridge for use in the same - Google Patents
Refrigerator for storing vials and cartridge for use in the same Download PDFInfo
- Publication number
- CN101218478B CN101218478B CN2006800195056A CN200680019505A CN101218478B CN 101218478 B CN101218478 B CN 101218478B CN 2006800195056 A CN2006800195056 A CN 2006800195056A CN 200680019505 A CN200680019505 A CN 200680019505A CN 101218478 B CN101218478 B CN 101218478B
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- CN
- China
- Prior art keywords
- refrigerator
- bottle
- formation
- guider
- door
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D25/00—Charging, supporting, and discharging the articles to be cooled
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D2400/00—General features of, or devices for refrigerators, cold rooms, ice-boxes, or for cooling or freezing apparatus not covered by any other subclass
- F25D2400/10—Refrigerator top-coolers
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D31/00—Other cooling or freezing apparatus
- F25D31/006—Other cooling or freezing apparatus specially adapted for cooling receptacles, e.g. tanks
Abstract
The invention relates to a refrigerator (1) for storing vials (10) containing a (bio) pharmaceutical substance, in particular vaccines for animals, comprising a cabinet (2) having an internal space (9) for accommodating the vials (10) arranged in columns, a cooling element for cooling the internal space (9) and at least one door (8) or dispenser for removing vials (10) from the internal space (9). A plurality of guides (12, 15) located inside the space (9) and adapted to slidingly accommodate columns of the vials (10). The invention further relates to a cartridge (11) suitable for use in the said refrigerator (1).
Description
Technical field
The present invention relates to store the refrigerator of bottle, hold (biology) drug substance, especially animal vaccine in the bottle, this refrigerator comprises: have the cupboard of inner space, described inner space holds the bottle that the formation shape is arranged; Cool off the cooling element of this inner space; With at least one door or distributor of taking out bottle from this inner space.The invention still further relates to the tube that is suitable for being used in a kind of like this refrigerator.
Background technology
The refrigerator of storage bottle is known.German utility model DE 20007889 U1 relate to the cool-bag (in the accompanying drawings by numeral 1 expression) of medicine, thermal deflection plate 4 and blower fan that it has thermal insulation layer 2, injection support, links with Poltier module 5.Electronic Control piece 6 has Control of Voltage, working voltage control system, overheat protecting system and thermostat.Controll block 6 control Poltier module 5 and blower fans.And front wall is as door.
WO 87/07704 relates to the cool room that holds the insulin injection.Its size makes it can hold the injection that make in all Europe.This cool room is suitable for not having meter to be used for the refrigeration unit of power supply and battery use.
DK 468 380 relates to the device that is used for by the refrigerator of driven compressor, it has the cold collector of placing against sidewall in the refrigerator storeroom, this is for refrigerator can be used with lasting storage temperature, or even under the long-time condition of interrupting of power of compressor.Cold collector is made up of many vertical tubes 17, and vertical tube 17 is abutting one another erects and accommodate the fluid with about 0 ℃ of freezing point.By top frame 18 pipe 17 is put into the position, top frame 18 rests on the plane 19 in the refrigerator top edge and has the skewed slot that is used for pipe.
Summary of the invention
Target of the present invention provides improved refrigerator, is used for the bottle that storage holds (biology) drug substance.
The invention provides a kind of refrigerator of storing bottle, described bottle holds the bio-pharmaceutical material, and this refrigerator comprises: have the cupboard of inner space, described inner space holds the bottle that the formation shape is arranged; And the cooling element that cools off this inner space, it is characterized in that: each team in the described formation extends to door or the distributor that is used for from the refrigerator of this inner space taking-up bottle, a plurality of guiders are positioned at described space and are suitable for sliding and hold the formation of bottle, wherein for each described formation, described guider extends to door corresponding with this formation or the contiguous position of distributor along the length direction of this formation, thereby force the bottle that is arranged in this formation being remained on this formation before refrigerator takes out, the bottle in each formation or each set of queues holds different vaccines.
For this purpose, comprise guider according to refrigerator of the present invention, the formation that it is positioned at interior volume and is fit to hold slidably bottle.
Preferably, each guider or every cover guider comprise distribution portion, can be easily take out from guider at this bottle, and this distribution portion is preferably at each or respectively overlap on the end of guider.
That guider is convenient to is more orderly, safety and/or wholesomely use refrigerator, and to describe as following, can use one or more relatively little inlets, for example one or more relatively little door or distributors, distributor for example is one or more drawers or air-lock.
Preferably, described formation has on the direction of perpendicular elements, is being non-ly flatly to extend, and/or at least some guiders link to each other with the device that for example is spring, in order to the bottle of setovering towards distribution portion.In such embodiment, gravity and/or elastic force or similar power can be used in towards for example distribution portion at guider one end and promote bottle, thereby bottle is remained on the appropriate location of described distribution portion, and when the bottle in this part is removed, will remain bottle and push distribution portion to.
If door and distributor lay respectively at one or more formations distribution portion and can near the bottle of limited quantity or or even single bottle, the temperature fluctuation in the inner space just can reduce effectively so.
More preferably, described cupboard comprises at least two mutual separable housings, and first housing holds bottle, and second housing comprises cooling element.Thereby first housing is portable and can be carried by for example doctor or animal doctor.If especially first housing will betransported relatively large distance or separate for a long time with second housing, so preferably described people's conveying arrangement or for example second operating room or auxiliary building auxiliary second housing that comprises cooling element is equipped with, described conveying arrangement is generally automobile or lorry.
The present invention also relates to be used in the tube in the above-mentioned refrigerator, it comprises the guider that is suitable for holding slidably a plurality of bottles.This tube can and be convenient to distribute bottle and fill up cupboard again as the device of packing a plurality of bottles.
In framework of the present invention, term " tube " comprises box, clip and even is suitable for sliding and keeps any entity of a row bottle.
Description of drawings
Illustrate in greater detail the present invention now with reference to accompanying drawing, the schematically illustrated presently preferred embodiments of accompanying drawing.
Fig. 1 is the perspective view according to refrigerator of the present invention, and a top doors and a bottom door opened.
Fig. 2 A and 2B are that what to be suitable for using in refrigerator is respectively the perspective view of tube empty and that fill up.
Should be noted in the discussion above that accompanying drawing needn't draw in proportion, and be omitted for understanding the nonessential details of the present invention.Term " top ", " bottom ", " vertically ", " level ", " preceding ", " back ", " side " and similar terms relate to as in the accompanying drawing directed embodiment.And identical Reference numeral is represented identical at least substantially or is carried out the element of identical function at least substantially.
The specific embodiment
Fig. 1 illustrates according to refrigerator 1 of the present invention, and refrigerator 1 is used to store the bottle that holds pharmacy or bio-pharmaceutical material, especially animal vaccine.Refrigerator 1 comprises cupboard 2, and cupboard 2 has and is installed on the wall or the back casing 3 of vehicle interior and the procapsid 4 that for example is installed in back casing 3 front sides by devices such as hook and groove, magnet or Velcros separably.
Back casing 3 holds the cooling element (not shown), and it preferably is clipped in two thermal transfer plate, the Peltier's element between two blocks of aluminium sheets for example, and the plate in front extends across sizable part of back casing 3 antethecas.In bottom and top surface, comprise air grid 5.And back casing 3 comprises the ventilation equipment that are used for cooling off the hot side of cooling element, connect cooling element with ventilation equipment and be arranged on the control module of the connector of back casing 3 antethecas, the battery pack or the transformer that will be connected with power supply or Vehicular battery.
Procapsid 4 is corresponding with back casing 3 and comprise three cover doors 6,7,8 on width and height, all provide the inlet that enters inner space 9, inner space 9 holds the bottle of arranging in a large number 10 in the formation vertical along the cardinal principle of guider, will illustrate as following.Lowermost door 8 is vertical substantially to be extended, and the top edge and the procapsid 4 of these each in 8 are pivotally connected.By rotating these in 8 forward and to head lamp brush guard pivot, one group for example the lowermost bottle 10 in three adjacent columns expose, thereby make it possible to from each row, take out bottle 10.
Uppermost door 6 is horizontal-extendings and being pivotally mounted in the upper wall of procapsid 4 substantially.Rotate these in 6 by pivot upwards and backward, another group for example the bottle 10 of three adjacent columns expose.
When procapsid 4 was installed on the back casing 3, the rear wall of procapsid 4 adjoined Peltier's element.
Although the fixing guider that the formation of 9 inside is extended along the inner space, for example vertical pipe or partition walls will provide effective means for holding bottle 10 slidably, and preferably the tube 11 of elongation is installed in space 9 movably side by side.
Fig. 2 A and 2B illustrate the example of planning to be used in the preferred cartridge 11 in the refrigerator 1 of the present invention.This preferred cartridge 11 comprises two parallel side walls 12 that are connected with diapire 14 by rear wall 13.Sidewall 12 is to open less times greater than the separating distance of bottle 10 width.In this preferred implementation, diapire 14 adapts with the shape of bottle 10, also promptly has semi-circular cross-section.Two retainer belts 15 that tilt to the plane of symmetry of tube 11 almost extend along the whole length of sidewall 12, also promptly extend to corresponding with the width of bottle 10, as to be higher than diapire 14 distance.Retainer belt 15 and sidewall 12 form jointly to slide and keep effective guiders of row bottles 10, and define distribution locations in tube 11 bottoms, also are that lowermost bottle 10 can be extracted from tube 11 on the direction vertical with the row cardinal principle of residue bottle.
Be full of tube 11 although distribution locations also can be used in principle by bottle, preferably tube 11 also comprises preferred filling part on the other end of tube 11, shown in Fig. 2 A and 2B.That is to say that tube 11 can be filled the open top that bottle adds tube 11 by the slip of bottleneck between retainer belt 15 by bottle 10.
In the accompanying drawing illustrated embodiment, the antetheca of procapsid 4 also comprises one or more for example two independent gates 7, and gate 7 provides and enters the inlet of inner space 9 to keep in repair or to clean.Alternatively, antetheca is fixedlyed connected with procapsid 4 or is formed an integral body with procapsid 4.
Antetheca also comprises switch and the warning lamp that opens or closes Peltier's element, and described warning lamp is that minimum temperature has reached and indicates the selected limiting value that is stored in the control module.Alternatively or additionally, can be cupboard provides and temperature required adjuster for example is set, shows this setting and/or the display of actual temperature (for example measured by the thermocouple that is arranged in the inner space) and/or the loudspeaker that has given the alarm when selected limiting value has reached.The rear wall of procapsid is provided with the connector homologue, its with the back casing antetheca on separable connection of connector, thereby with described switch, warning lamp, adjuster, display and other elements that are used to operate refrigerator be connected with control module.
The wall of back and previous section is preferably made by injection moulded thermoplastic polymer, and for example ABS, PC or fiber are filled PP.At least the wall of procapsid is heat-insulating, and it is by for example one deck expansion polyurethane or polyester form and optionally be clipped in reflective aluminum film between the described injection moulded thermoplastic polymer inside and outside wall.Preferably by strip of paper used for sealing 16, for example rubber ring centers on insulated part on the door.
In addition, preferably the part antetheca, for example the bottom part of relatively large door 7 is made by transparent material, for example make, thereby make to use the personnel of this cupboard can see which bottle with transparent double-deck PS or PC, and in seeing therefore where which drug substance goes.
Described tube is also preferably by injection moulded thermoplastic polymer, and especially transparent PC makes.
In use, refrigerator for example is installed in the animal doctor and performs the operation on the locular wall, connects Peltier's element, and when reaching enough low temperature, open the top and each wound packages that all holds a plurality of bottles gone into the inner space.Each or each bottle of organizing in the tube hold different vaccines, and comprise the tube that for example holds PPi, Parvo-C, Corona, Kc, DHPPI and the Puppy DP freeze-drying bead of (as indicated in the Intervet catalogue 2005) (freeze-dried powder or " cake ").When particular vaccine when to be administered, open the door of corresponding bottom and from suitable row, take out bottle, the dilution that is generally water, water-in-oil emulsion or O/w emulsion is injected this bottle to obtain injectable material.
From foregoing description, can be clear that according to refrigerator of the present invention promote or or even the use of having forced more orderly, safety and/or health, and only the cooling air can spill in the process of taking out bottle in the refrigerator of limited quantity, has fully avoided the remarkable minimizing of internal temperature.
Although use the personnel of refrigerator of the present invention---for example animal doctor or assistant can take other bottle to fill described tube, preferably distribute the tube of prepackage or or even hold prepackage (preceding) housing of bottle formation by existing channel.
The present invention is not subjected to the restriction of above-mentioned embodiment, and it can change within the scope of the claims in many ways.For example, cupboard preferably includes the syringe of storage prepackage or the additional compartment of dilution.For preventing that injectable substance from becoming too cold, cooling (amber ear card) element does not preferably extend across the compartment of storage dilution or this compartment and cooling element is isolated.
Claims (11)
1. store the refrigerator (1) of bottle (10), described bottle holds the bio-pharmaceutical material, and this refrigerator comprises: have the cupboard (2) of inner space (9), described inner space (9) hold the bottle (10) that the formation shape is arranged; And the cooling element that cools off this inner space (9), it is characterized in that: each formation in the described formation extends to the door or the distributor of the refrigerator that is used for (9) the taking-up bottles (10) from this inner space, a plurality of guiders (12,15) be positioned at described space (9) and be suitable for sliding and hold the formation of bottle (10), wherein for each described formation, described guider extends to door corresponding with this formation or the contiguous position of distributor along the length direction of this formation, thereby force the bottle that is arranged in this formation being remained on this formation before refrigerator takes out, the bottle in each formation or each set of queues holds different vaccines.
2. according to the refrigerator (1) of claim 1, wherein each or the complete guider (12,15) of every cover comprise distribution portion, can be in this dispenser office from guider (12,15) take out bottle (10) in, this distribution portion is preferably at each or respectively overlap on the end of guider (12,15).
3. according to the refrigerator (1) of claim 1 or 2, wherein said formation is extended having on the direction of perpendicular elements, and/or at least some guiders (12,15) or some cover guiders (12,15) with link to each other in order to device towards distribution portion biasing bottle (10).
4. according to the refrigerator (1) of claim 1 or 2, each guider (12,15) or respectively to overlap guider (12,15) be a part that is installed in the tube (11) in the described space (9) in removable mode wherein.
5. according to the refrigerator (1) of claim 1 or 2, wherein said door (8) or distributor lay respectively at one or more formations distribution portion and can be near the bottle (10) of limited quantity.
6. according to the refrigerator (1) of claim 5, wherein said door (8) or distributor respectively can be near the parts of these row that mostly are three row most.
7. according to the refrigerator (1) of claim 1 or 2, comprise at least one door (6,8) at the two ends of guider (12,15).
8. according to the refrigerator (1) of claim 1 or 2, wherein cupboard (2) comprises at least two mutual separable housings (3,4), and first housing (4) has described inner space (9) and guider (12,15), and second housing (3) comprises described cooling element.
9. according to the refrigerator (1) of claim 1 or 2, wherein antetheca to the small part of cupboard (2) is transparent.
10. according to the refrigerator (1) of claim 1, wherein said bio-pharmaceutical material is an animal vaccine.
11. be used in the tube (11) in the refrigerator (1) according to aforementioned arbitrary claim, it comprises the guider (12,15) that is suitable for holding slidably a plurality of bottles (10).
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/144,955 | 2005-06-03 | ||
| EP05104880.9 | 2005-06-03 | ||
| EP05104880 | 2005-06-03 | ||
| US11/144,955 US8156755B2 (en) | 2005-06-03 | 2005-06-03 | Refrigerator for storing vials and cartridge for use in the same |
| PCT/EP2006/062819 WO2006128897A1 (en) | 2005-06-03 | 2006-06-01 | Refrigerator for storing vials and cartridge for use in the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101218478A CN101218478A (en) | 2008-07-09 |
| CN101218478B true CN101218478B (en) | 2011-03-02 |
Family
ID=36748359
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2006800195056A Active CN101218478B (en) | 2005-06-03 | 2006-06-01 | Refrigerator for storing vials and cartridge for use in the same |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1891388B1 (en) |
| JP (1) | JP5006872B2 (en) |
| CN (1) | CN101218478B (en) |
| AU (1) | AU2006254092B2 (en) |
| BR (1) | BRPI0611010B1 (en) |
| DK (1) | DK1891388T3 (en) |
| ES (1) | ES2714380T3 (en) |
| PT (1) | PT1891388T (en) |
| RU (1) | RU2367858C1 (en) |
| WO (1) | WO2006128897A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT201700055004A1 (en) * | 2017-05-22 | 2018-11-22 | Simone Morosini | CARTRIDGE HOLDER CONTAINER |
| CN114963640A (en) * | 2021-02-18 | 2022-08-30 | 内蒙古伊利实业集团股份有限公司 | Door assembly and refrigerator |
| CN113623914B (en) * | 2021-07-22 | 2023-05-02 | 肇庆医学高等专科学校 | Preventive medicine bacterin low temperature storage case |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2826471A (en) * | 1953-09-22 | 1958-03-11 | Gen Electric | Frozen fruit juice dispenser |
| US4194647A (en) * | 1978-01-30 | 1980-03-25 | Spurrier Harry A | Cooler chest and dispenser structure |
| US5142872A (en) * | 1990-04-26 | 1992-09-01 | Forma Scientific, Inc. | Laboratory freezer appliance |
| US5950450A (en) * | 1996-06-12 | 1999-09-14 | Vacupanel, Inc. | Containment system for transporting and storing temperature-sensitive materials |
| CN2648362Y (en) * | 2003-08-10 | 2004-10-13 | 叶永丰 | Miniature refrigerating box for insulin |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1695956A (en) * | 1928-12-18 | frig k | ||
| US1633588A (en) * | 1923-04-30 | 1927-06-28 | Klinenberg Edward | Ice-cream cabinet |
| JPS6333853U (en) * | 1986-08-21 | 1988-03-04 | ||
| JPS6453885U (en) * | 1987-09-29 | 1989-04-03 | ||
| JP3354219B2 (en) * | 1993-07-07 | 2002-12-09 | 三洋電機株式会社 | Chemical storage |
| JP2001349653A (en) * | 2000-06-08 | 2001-12-21 | Ishikawajima Harima Heavy Ind Co Ltd | Refrigerating and warming container |
| US6536609B2 (en) * | 2000-12-29 | 2003-03-25 | Merck & Co., Inc. | Vial dispenser |
-
2006
- 2006-06-01 DK DK06763444.4T patent/DK1891388T3/en active
- 2006-06-01 JP JP2008514106A patent/JP5006872B2/en not_active Expired - Fee Related
- 2006-06-01 PT PT06763444T patent/PT1891388T/en unknown
- 2006-06-01 BR BRPI0611010A patent/BRPI0611010B1/en active IP Right Grant
- 2006-06-01 WO PCT/EP2006/062819 patent/WO2006128897A1/en active Application Filing
- 2006-06-01 AU AU2006254092A patent/AU2006254092B2/en not_active Ceased
- 2006-06-01 CN CN2006800195056A patent/CN101218478B/en active Active
- 2006-06-01 ES ES06763444T patent/ES2714380T3/en active Active
- 2006-06-01 RU RU2007149558/12A patent/RU2367858C1/en not_active IP Right Cessation
- 2006-06-01 EP EP06763444.4A patent/EP1891388B1/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2826471A (en) * | 1953-09-22 | 1958-03-11 | Gen Electric | Frozen fruit juice dispenser |
| US4194647A (en) * | 1978-01-30 | 1980-03-25 | Spurrier Harry A | Cooler chest and dispenser structure |
| US5142872A (en) * | 1990-04-26 | 1992-09-01 | Forma Scientific, Inc. | Laboratory freezer appliance |
| US5950450A (en) * | 1996-06-12 | 1999-09-14 | Vacupanel, Inc. | Containment system for transporting and storing temperature-sensitive materials |
| CN2648362Y (en) * | 2003-08-10 | 2004-10-13 | 叶永丰 | Miniature refrigerating box for insulin |
Also Published As
| Publication number | Publication date |
|---|---|
| DK1891388T3 (en) | 2019-04-08 |
| JP2008545485A (en) | 2008-12-18 |
| JP5006872B2 (en) | 2012-08-22 |
| EP1891388A1 (en) | 2008-02-27 |
| EP1891388B1 (en) | 2018-12-26 |
| CN101218478A (en) | 2008-07-09 |
| BRPI0611010B1 (en) | 2018-10-16 |
| AU2006254092B2 (en) | 2010-10-14 |
| WO2006128897A1 (en) | 2006-12-07 |
| AU2006254092A1 (en) | 2006-12-07 |
| BRPI0611010A2 (en) | 2011-02-22 |
| PT1891388T (en) | 2019-04-08 |
| ES2714380T3 (en) | 2019-05-28 |
| RU2367858C1 (en) | 2009-09-20 |
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| PB01 | Publication | ||
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| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |