CN101214315A - Medicament for preventing and treating gynaecologic hemorrhage and preparation thereof - Google Patents
Medicament for preventing and treating gynaecologic hemorrhage and preparation thereof Download PDFInfo
- Publication number
- CN101214315A CN101214315A CNA2008100544202A CN200810054420A CN101214315A CN 101214315 A CN101214315 A CN 101214315A CN A2008100544202 A CNA2008100544202 A CN A2008100544202A CN 200810054420 A CN200810054420 A CN 200810054420A CN 101214315 A CN101214315 A CN 101214315A
- Authority
- CN
- China
- Prior art keywords
- radix
- medicine
- hemorrhage
- preventing
- uterine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The present invention relates to a pure Chinese medicine for preventing and curing uterine hemorrhage, including prepared rehmannia rhizome, angelica, raw white peony, hemlock parsley, dangshen, milk veteh, fried largehead atractylode, broiled liquorice, black lotus seed, pulp of dogwood fruit, fried himalayan teasel root, fried cortex eucommiae, radix notoginseng, calcined keel and gentian root. All drugs are cleaned and sun-dried, then mixed in proportion and smashed into 100 mesh fine powder; the smashed drugs is added with a double of honey and evenly mixed, then disinfected and made into honey pill products. According to clinical observation, the present invention used for birth-control preventive medication has the advantages of shortening the bleeding time after operation, speeding up the uterine repair, rapidly curing the uterine bleeding and preventing uterine blood diseases, reducing the pain of patients without any side effect, seeking both temporary and permanent solutions, and having significant clinical value for preventing birth-control complications and increasing birth-control quality.
Description
Technical field
The present invention relates to a kind of medicine, be specifically related to medicine of a kind of prevention and treatment gynecological bleeding and preparation method thereof.
Background technology
Gynecological bleeding claims gynecologic blood diseases again, is meant that the neuroendocrine system dysfunction of regulating reproduction causes a kind of disease of metrorrhagia, is equivalent to motherland's medical science " metrorrhagia " category.As: menorrhagia, menostaxis, dripping not to the utmost, hemorrhage, the hysteromyoma hemorrhage of hemorrhage behind the cycle disorder, dysfunctional uterine hemorrhage, hemorrhage due to placement of IUD, artificial abortion, postpartum subinvolution of uterus, endometrial hyperplasia, ovarian cyst be hemorrhage etc.Be clinical typical commonly encountered diseases, frequently-occurring disease also is one of difficult serious symptom of comparatively paying close attention to of gynecological.Though the various treatment meanss energy respite symptoms of primary disease do not have breakthrough in recent years, are main treatment measure with hormone, operation, anti symptom treatment (hemorrhage such as YUNNAN BAIYAO, GONGXUENING, palace blood stop, FUXUEKANG, FUKANG treasured) still.But curative effect is undesirable, so that a lot of patient relies on hormone for a long time or hardship, especially " uterectomy " of the ailing torment of grining and bear it have brought huge injury for women's physical and mental health.In addition, the side effect (irregular colporrhagia) of family planning method (going up ring, contraceptive, artificial abortion, medicine stream etc.) is paid attention to relevant government department by increasing doctor, at present also do not have good method to reduce or evade the side effect of various family planning methods, bring many worries to female life.
Summary of the invention
The objective of the invention is at the deficiencies in the prior art, provide a kind of can rapid healing gynecological bleeding and prevention gynecologic blood diseases disease, alleviate the patient suffering, have no side effect, the pure Chinese medicinal preparation for the treatment of both the principal and secondary aspects of a disease.
Another goal of the invention of the present invention provides the preparation method of this medicine.
The medicine of a kind of prevention of the present invention and treatment gynecological bleeding is the medicament of being made by the following materials based on weight medicine:
Radix Rehmanniae Preparata 8～12, Radix Angelicae Sinensis 3～6, Radix Paeoniae Alba 5～8, Rhizoma Chuanxiong 3～6, Radix Codonopsis 5～8, the Radix Astragali 8～12, Rhizoma Atractylodis Macrocephalae (parched) 8～12, Radix Glycyrrhizae Preparata 2～4, Semen Caesalpiniae Minacis 8～12, Fructus Corni 3～6, stir-fry Radix Dipsaci 5～8, Cortex Eucommiae (parched) 5～8, Radix Notoginseng 2～4, Os Draconis (calcined) 5～8, Radix Gentianae 3～6.
Above-mentioned each component can be made said dosage form on any pharmaceutics, and as decoction, tablet, powder, capsule, electuary, oral liquid, honeybee ball etc., the preferred dosage form of the present invention is a honeyed pill.
The preparation method of the medicine of prevention of the present invention and treatment gynecological bleeding: be above-mentioned medicine to be cleaned dry, be mixed in proportion and be ground into 100 order fine powders that the one times of amount Mel that adds the medicine of pulverizing is mixed well, sterilization is made the honeyed pill product.
In the prescription of the present invention: Radix Rehmanniae Preparata, Radix Angelicae Sinensis, Radix Paeoniae Alba, Rhizoma Chuanxiong, Radix Codonopsis, the Radix Astragali are the name Fang Sheng of the benefiting qi and nourishing blood soup of healing, and can control all diseases of losing blood.How the gynecologic blood diseases patient has lost blood a few days or more of a specified duration when going to a doctor, and QI and blood sufferer accounts for significant proportion, and benefiting qi and nourishing blood, astringing for hemostasis can not only stop the generation of excessive bleeding associated with exhaustion of QI, can also correct the complication that causes because of severe loss of blood.Rhizoma Atractylodis Macrocephalae (parched), Radix Glycyrrhizae Preparata, Semen Caesalpiniae Minacis add Radix Codonopsis, big invigorating middle warmer Jiao's of the Radix Astragali gas, and spleen invigorating is astringent or styptic treatment for spontaneous sweating, have QI and blood marrow all over the body under one's command, admittedly collapse hemostasis.Fructus Corni, stir-fry Radix Dipsaci, Cortex Eucommiae (parched) add Radix Rehmanniae Preparata the kidney invigorating essence greatly, give birth to marrow, and Gu Chong only collapses.Radix Notoginseng, Os Draconis (calcined) promoting blood circulation and hemostasis admittedly collapse convergence, are closed the door of blood circulating out of vessels.Radix Gentianae symphysis Radix Paeoniae Alba clearing away liver-fire, the suppressing the hyperactive liver sun is held back liver-yin, tonifying liver blood.Many medicines are made a concerted effort, and antiinflammatory, hemostasis, the repair of promotion uterus are remarkable, can be widely used in treatment, prevent various gynecologic blood diseases.
For showing effect and the effect of medicine of the present invention to prevention and the treatment of treatment gynecological bleeding, randomly draw 660 routine gynecologic blood diseases patients and 80 routine family plannings (going up ring, medicine stream) prevention administration person, clinical observation is as follows:
Drug therapy gynecologic blood diseases 660 routine clinical observations of the present invention
1, physical data
Randomly draw gynecologic blood diseases patient 660 examples, the oldest 56 years old, minimum 12 years old.The course of disease is the longest 11 years, and is the shortest 20 days.Wherein, adolescence anovulatory dysfunctional uterine hemorrhage 108 examples (wherein metrorrhagia companion shock 1 example), child-bearing period anovulatory dysfunctional uterine hemorrhage 119 examples (desiring the person's of hysterectomizing 3 examples before the prescription on individual diagnosis), climacteric anovulatory dysfunctional uterine hemorrhage 185 examples (wherein metrorrhagia companion shock 2 examples), contact bleeding 12 examples, put hemorrhage 64 examples of ring property (the ring position moves down 5 examples), hemorrhage 40 examples behind the artificial abortion, postpartum subinvolution of uterus 32 examples, threatened abortion 1 example, 2 examples of having blood in stool menstrual period, hysteromyoma hemorrhage 60 examples (desiring the person's of hysterectomizing 19 examples before the prescription on individual diagnosis), hemorrhage 17 examples of ovarian cyst, hemorrhage 11 examples of endometrial hyperplasia (recidivist's 4 examples behind the clearing heat in the pericardium), pmb 9 examples.Above patient has the above hospitalize history in county more, and exhausted medicine and method have: diethylstilbestrol, Marvelon, medroxyprogestetone acetate, premarin, the dilatation and curettage, intravenously administrable, Herba Clinopodii, YUNNAN BAIYAO, hoof nail polypeptide sheet, GONGXUENING, FUXUEKANG, blood peace etc.
2, diagnostic criteria
After getting rid of tumor, the damage of uterus trunk and disease in the blood system, all menstrual blood volume are greater than 120ml (with sanitary towel more than 15), and menstrual period are greater than 7 days, or irregular colporrhagia person all can examine and is gynecologic blood diseases.
3, therapeutic scheme
Oral medicine of the present invention, one time 9 gram, one day 3 times, warm water delivery service after meal.12 days is a course of treatment.Inactive other medicines during treatment, endometrial thickness the person give uterine curettage.
4, curative effect determinate standard
The recovery from illness: take 1～2 the course of treatment transference cure, follow up a case by regular visits to and do not see recurrence in 3 months.
Effectively: recur after taking 1～2 the hemorrhage minimizing course of treatment or drug withdrawal.
Invalid: serve on 2 the course of treatment symptom do not have obvious improvement.
5, efficacy analysis
5,1 therapeutic outcome
Table 1 Drug therapy gynecologic blood diseases 660 routine results of the present invention
| Diagnosis | Case load | Curative effect | ||
| Invalid number | Effective number | The recovery from illness number | ||
| Adolescence anovulatory dysfunctional uterine hemorrhage child-bearing period anovulatory dysfunctional uterine hemorrhage climacteric anovulatory dysfunctional uterine hemorrhage contact bleeding is put behind the hemorrhage artificial abortion of ring property the hemorrhage postpartum subinvolution of uterus threatened abortion hemorrhage pmb of the hemorrhage endometrial hyperplasia of hysteromyoma hemorrhage ovarian cyst of having blood in stool menstrual period and is amounted to | 108 119 185 12 64 40 32 1 2 60 17 11 9 660 | 3 ? ? 2 ? ? ? ? ? 1 1 ? ? 7 | 10 11 19 1 2 ? 1 ? ? 7 3 ? ? 54 | 95 108 166 9 62 40 31 1 2 52 13 11 9 599 |
5, do not see untoward reaction in the 2 adverse effect therapeutic processes.
6, conclusion
Drug therapy gynecologic blood diseases 660 examples of the present invention, total effective rate 98.9% shows that Drug therapy gynecologic blood diseases of the present invention is evident in efficacy.Do not see any untoward reaction in the therapeutic process.
Medicine of the present invention and conventional method prevention family planning hemorrhage 80 routine paired observations
1, data and method
1.1 physical data is observed 80 examples altogether, does not have any complication, the age was wherein gone up ring 40 examples between 23～36 years old, and medicine flows 40 examples, and every class patient is divided into treatment at random and organizes 20 examples, matched group 20 examples.
1.2 the oral medicine of the present invention of medication treatment group postoperative, one time 9 gram, one day 3 times.The oral cefradine of matched group postoperative, a 500mg, one day 3 times; Herba Leonuri granule, one time 15 gram, one day 2 times.The equal continuous use of treatment group and matched group 7 days.Acute symptom is with examining.
1.3 observation index is observed the routine number of postoperative rehabilitation in 7 days, 14 days, 21 days (stopped bleeding does not have other complication), observes menstruation situation in 6 months.
2, efficacy analysis
2.1 treatment group and matched group rehabilitation are relatively
Ring back rehabilitation relatively on the table 2 liang group
| Classification | Case | 7 days | 14 days | 21 days | Menstruation situation in 6 months |
| The treatment group | 20 people | 17 people | 3 people | Menstruation is normal substantially | |
| Matched group | 20 people | 10 people | 7 people | 3 people | Menstruation is not normal or through amount showed increased 5 examples more in the past |
Table 3 liang group medicine stream back rehabilitation relatively
| Classification | Case | 7 days | 14 days | 21 days (uterine curettage) | Menstruation situation in 6 months |
| The treatment group | 20 people | 12 people | 8 people | Menstruation is normal substantially | |
| Matched group | 20 people | 5 people | 11 people | 4 people | Not normal 3 examples of menstruation, metrorrhagia 1 example |
2.2 two groups of adverse effect comparisons are not all found adverse effect for two groups.
Medicine of the present invention is used for the family planning preventive administration, the postoperative hemorrhage time is shortened, the uterus repair function is accelerated, energy rapid healing gynecological bleeding and prevention gynecologic blood diseases disease, alleviate the patient suffering, have no side effect, treating both the principal and secondary aspects of a disease, to prevention family planning complication with improve the family planning quality important clinical value is arranged.
The specific embodiment
Embodiment 1:
Press following weight (part) proportioning weighting raw materials:
Radix Rehmanniae Preparata 10g, Radix Angelicae Sinensis 5g, Radix Paeoniae Alba 6.7g, Rhizoma Chuanxiong 5g, Radix Codonopsis 6.7g, Radix Astragali 10g, Rhizoma Atractylodis Macrocephalae (parched) 10g, Radix Glycyrrhizae Preparata 3.3g, Semen Caesalpiniae Minacis 10g, Fructus Corni 5g, stir-fry Radix Dipsaci 6.7g, Cortex Eucommiae (parched) 6.7g, Radix Notoginseng 3.3g, Os Draconis (calcined) 6.7g, Radix Gentianae 5g;
Concrete preparation method is:
Above-mentioned medicine cleaned dry, be mixed in proportion and be ground into 100 order fine powders, add a times of the medicine of pulverizing and measure Mel and mix well, sterilization is made the honeyed pill product.
Embodiment 2:
Take by weighing raw material by following weight (part) proportioning:
Radix Rehmanniae Preparata 8g, Radix Angelicae Sinensis 3g, Radix Paeoniae Alba 5g, Rhizoma Chuanxiong 3g, Radix Codonopsis 5g, Radix Astragali 8g, Rhizoma Atractylodis Macrocephalae (parched) 8g, Radix Glycyrrhizae Preparata 2g, Semen Caesalpiniae Minacis 8g, Fructus Corni 3g, stir-fry Radix Dipsaci 5g, Cortex Eucommiae (parched) 5g, Radix Notoginseng 2g, Os Draconis (calcined) 5g, Radix Gentianae 3g.
Concrete preparation method is:
Above-mentioned medicine cleaned dry, be mixed in proportion and be ground into 100 order fine powders, add a times of the medicine of pulverizing and measure Mel and mix well, sterilization is made the honeyed pill product.
Embodiment 3:
Take by weighing raw material by following weight (part) proportioning:
Radix Rehmanniae Preparata 12g, Radix Angelicae Sinensis 6g, Radix Paeoniae Alba 8g, Rhizoma Chuanxiong 6g, Radix Codonopsis 8g, Radix Astragali 12g, Rhizoma Atractylodis Macrocephalae (parched) 12g, Radix Glycyrrhizae Preparata 4g, Semen Caesalpiniae Minacis 12g, Fructus Corni 6g, stir-fry Radix Dipsaci 8g, Cortex Eucommiae (parched) 8g, Radix Notoginseng 4g, Os Draconis (calcined) 8g, Radix Gentianae 6g.
Concrete preparation method is:
Above-mentioned medicine cleaned dry, be mixed in proportion and be ground into 100 order fine powders, add a times of the medicine of pulverizing and measure Mel and mix well, sterilization is made the honeyed pill product.
Claims (4)
1. the medicine of prevention and treatment gynecological bleeding is characterized in that: the medicament of being made by the following materials based on weight medicine:
Radix Rehmanniae Preparata 8～12, Radix Angelicae Sinensis 3～6, Radix Paeoniae Alba 5～8, Rhizoma Chuanxiong 3～6, Radix Codonopsis 5～8,
The Radix Astragali 8～12, Rhizoma Atractylodis Macrocephalae (parched) 8～12, Radix Glycyrrhizae Preparata 2～4, Semen Caesalpiniae Minacis 8～12, Fructus Corni 3～6,
Fry Radix Dipsaci 5～8, Cortex Eucommiae (parched) 5～8, Radix Notoginseng 2～4, Os Draconis (calcined) 5～8, Radix Gentianae 3～6.
2. the medicine of a kind of prevention according to claim 1 and treatment gynecological bleeding, it is characterized in that: described medicament is a said dosage form on any pharmaceutics.
3. the medicine of a kind of prevention according to claim 2 and treatment gynecological bleeding, it is characterized in that: described medicament is a honeyed pill.
4. the preparation method of the medicine of described a kind of prevention of claim 3 and treatment gynecological bleeding, it is characterized in that: above-mentioned medicine is cleaned dried, be mixed in proportion and be ground into 100 order fine powders, the one times of amount Mel that adds the medicine of pulverizing is mixed well, sterilization is made the honeyed pill product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008100544202A CN101214315B (en) | 2008-01-08 | 2008-01-08 | Medicament for preventing and treating gynaecologic hemorrhage and preparation thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008100544202A CN101214315B (en) | 2008-01-08 | 2008-01-08 | Medicament for preventing and treating gynaecologic hemorrhage and preparation thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101214315A true CN101214315A (en) | 2008-07-09 |
| CN101214315B CN101214315B (en) | 2010-06-09 |
Family
ID=39620863
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2008100544202A Expired - Fee Related CN101214315B (en) | 2008-01-08 | 2008-01-08 | Medicament for preventing and treating gynaecologic hemorrhage and preparation thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101214315B (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101336997B (en) * | 2008-08-11 | 2010-12-22 | 江苏济川制药有限公司 | Medicine for hemorrhage after drug abortion |
| CN101564463B (en) * | 2009-05-27 | 2012-04-25 | 姜红 | Medicament for treating functional uterine hemorrhage |
| CN102961506A (en) * | 2012-12-05 | 2013-03-13 | 张玉玲 | Medicine for nursing functional uterine bleeding and preparation method thereof |
| CN104258090A (en) * | 2014-10-23 | 2015-01-07 | 陈济超 | Astringent preparation for woman menostaxis and preparation method thereof |
| CN104257933A (en) * | 2014-10-23 | 2015-01-07 | 陈济超 | Qi-tonifying and yin-nourishing preparation for woman menostaxis and preparation method thereof |
| CN106421253A (en) * | 2016-11-23 | 2017-02-22 | 张晓燕 | Traditional Chinese medicine composition for treating uterine bleeding |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1679913A (en) * | 2005-02-03 | 2005-10-12 | 贵阳德昌祥药业有限公司 | Gynecologic rehabilitation capsules for treating gynecopathy |
-
2008
- 2008-01-08 CN CN2008100544202A patent/CN101214315B/en not_active Expired - Fee Related
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101336997B (en) * | 2008-08-11 | 2010-12-22 | 江苏济川制药有限公司 | Medicine for hemorrhage after drug abortion |
| CN101564463B (en) * | 2009-05-27 | 2012-04-25 | 姜红 | Medicament for treating functional uterine hemorrhage |
| CN102961506A (en) * | 2012-12-05 | 2013-03-13 | 张玉玲 | Medicine for nursing functional uterine bleeding and preparation method thereof |
| CN102961506B (en) * | 2012-12-05 | 2014-04-02 | 张玉玲 | Medicine for nursing functional uterine bleeding and preparation method thereof |
| CN104258090A (en) * | 2014-10-23 | 2015-01-07 | 陈济超 | Astringent preparation for woman menostaxis and preparation method thereof |
| CN104257933A (en) * | 2014-10-23 | 2015-01-07 | 陈济超 | Qi-tonifying and yin-nourishing preparation for woman menostaxis and preparation method thereof |
| CN106421253A (en) * | 2016-11-23 | 2017-02-22 | 张晓燕 | Traditional Chinese medicine composition for treating uterine bleeding |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101214315B (en) | 2010-06-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102210847A (en) | Method for preparing medicinal composition capsules for treating dysmenorrheal and application thereof | |
| CN101214315B (en) | Medicament for preventing and treating gynaecologic hemorrhage and preparation thereof | |
| CN103585378A (en) | A Chinese medicinal composition for treating female infertility, and its preparation method | |
| CN102188583A (en) | Traditional Chinese medicine for treating infertility | |
| CN104857478A (en) | Medical composition for treating hysteromyoma and preparation method of medical composition | |
| CN100493585C (en) | Pure Chinese traditional medicine for treating chronic pelvic inflammatory disease and menoxenia disease | |
| CN104958448A (en) | Medicine for treating puerperal infection | |
| CN104474473A (en) | Traditional Chinese medicine composition for treating gynecologic inflammation and preparation method thereof | |
| CN101112481B (en) | A kind of medicine and preparation method thereof for treating dysfunctional blood | |
| CN104435614B (en) | A kind of pharmaceutical composition for the treatment of bed-wetting | |
| CN106421666A (en) | Pharmaceutical composition for treating liver depression and kidney deficiency type premature ovarian failure | |
| CN115282229B (en) | Traditional Chinese medicine composition for treating qi deficiency and blood stasis type coronary heart disease and preparation method thereof | |
| CN102343019B (en) | Chinese medicinal composition for treating amenorrhea and preparation method of preparation thereof | |
| CN102688434B (en) | A kind of traditional Chinese medicine for treating diabetes | |
| CN110201122B (en) | Traditional Chinese medicine composition for treating irregular menstruation and preparation method and application thereof | |
| CN105521332A (en) | Traditional Chinese medicinal composition for treating anal fissure, and preparation method and application thereof | |
| CN105770691A (en) | Medicinal preparation for treating cervical cancer and application thereof | |
| CN101366878A (en) | Traditional Chinese medicine for female acyesis and aphoria and preparation method thereof | |
| CN104800675A (en) | Medicament for treating active ulcerative colitis | |
| CN104800799A (en) | Traditional Chinese medicament for treating endometrial thickening with ovarian cysts | |
| CN104288581A (en) | Traditional Chinese medicine for treating threatened abortion | |
| CN103127398B (en) | Chinese medicament for treating cancers and preparation method thereof | |
| CN108904617A (en) | The pharmaceutical composition and its preparation method and application for treating cranial vascular disease | |
| CN105169111A (en) | Traditional Chinese medicine composition for treating chronic urticaria and application of traditional Chinese medicine composition | |
| CN105833209A (en) | Traditional Chinese medicine composition for treating endometriosis uterina |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20100609 Termination date: 20110108 |