CN101199778B - Compound medicament for treating synovitis - Google Patents

Abstract

The invention discloses a combined drug for treating synovitis, including an oral drug and an external application drug. The part rate of the oral drug is that Rhizoma Atractylodis 10-20 parts, Cortex Phellodendri 10-20 parts, Radix Stephaniae Tetrandrae 10-20 parts, Chaenomeles sinensis 10-20 parts, Harms Manyprickle Acanthopanax 10-20 parts, Radix Clematidis Chinensis 10-20 parts, Radix Angelicae Pubescentis 10-20 parts, Radix Paeoniae Alba 10-20 parts, Radix Astragali 30-60 parts, Semen Coicis 30-60 parts, Radix Codonopsis 30-60 parts, Radix Angelicae Dahuricae 8-15 parts and Ramulus Cinnamomi 8-15 parts. The part rate of the external application drug is that Radix Aconiti Kusnezoffii 2-20 parts, Radix Aconiti, 5-10 parts, Rhizoma et Radix Notopterygii 5-20 parts, Flos Carthami 5-10 parts, Radix Saposhnikoviae 10-20 parts, Ramulus Cinnamomi 5-10 parts, Ramulus Mori 2-5 parts, Rhizoma Atractylodis 5-10 parts, Radix Aconiti Lateralis Preparata 10-20 parts, Herba Epimedii 5-10 parts, Caulis Impatientis 10-20 parts, Radix Angelicae Pubescentis 10-20 parts, Radix Angelicae Dahuricae 10-20 parts and Herba Asari 10-20 parts. The combined drug of the invention achieves the potency of drug to be directly delivered to the focus through oral taking, local suffocating and foment and realizes good treatment effect.

Description

The composition of medicine of treatment synovitis

Technical field

The present invention relates to contain the medicinal preparation that derives from plant material, particularly a kind of composition of medicine that is used for the treatment of synovitis.

Background technology

Rheumatoid arthritis be a kind of be the chronic general immunity disease of feature with the articular synovitis, with brothers refer to, the easiest the getting involved in little joint such as toe, outbreak repeatedly lastingly.Early stage redness and swelling of joints burning pain and dysfunction, late period is ankylosis or deformity then, even it is useless to disable.

Rheumatoid arthritis is a kind of very complicated disease, its pathogeny is many-sided, up to the present the cause of disease of rheumatoid arthritis is not also illustrated fully, rheumatoid arthritis is to be feature with chronic synovitis, finally causes the autoimmune disease of cartilage absorption, osteoclasia and bone fibrosis.The characteristic of rheumatoid arthritis synovial membrane is changed into: synovial membrane type A cell propagation, and bone-marrow-derived lymphocyte, T lymphocyte and macrophages infiltration, polymorphonuclear cell is assembled and synovioblast propagation and fiber laydown.Wherein t cell activation is the core of inflammation.There is the scholar to think that the pathology of rheumatoid arthritis not only shows as the inflammation of synovium of joint, also relates to the blood supply and the microcirculation problem of the various tissues of joint part.Its pathologic basis is the deposition of immune complex in blood vessel wall, causes the rheumatoid arthritis vasculitis, can cause angiostenosis and thrombosis with vascular endothelial proliferation and swelling.

Rheumatoid arthritis is one of common disease that is detrimental to health, and home and overseas all has a lot of people inquiring into its cause of disease, seek effectively prevention and Therapeutic Method change its more after bad situation.Rheumatoid arthritis is a kind of cause of disease arthritis of not sure chronic progressive external as yet so far, it has been generally acknowledged that it is a kind of autoimmunity illness, be the result that body defending system is killed each other and caused, heredity, infection, cold humidity etc. all may be morbific factors in addition.

Wind, cold, wet three kinds of pathogens are combined into arthromyodynia mutually, and pathogenic factor is invaded skin, passages through which vital energy circulates, joint etc. and located, and hinders QI-blood circulation, pain, numbness, swelling, joint occur and condition of illness such as are weighing.Above-mentioned chronic disease, wide in China distribution region, patient's number is many, owing to there is not specific medicine, quite a few patient's obstinate is arranged and loses the confidence, and particularly for the synovitis patient, does not more have effective medicine clinically.The patient of the chronic joint pain that has, hormone abuse is as analgesic, and the result causes serious adverse consequences: as secular Peptic Ulcers, the recurrence of old tuberculosis, aseptic necrosis of femoral head.Oral western medicine for a long time with causing atrophic gastritis and gastric ulcer, all brings misery to the patient.

Synovitis mainly be synovial membrane hyperemia, swelling in early days, have fibrin to ooze out, form hydrarthrosis, typical inflammatory cell infiltration is arranged in the synovial membrane, involve articular cartilage and osseous tissue then, finally cause ankylosis.That ill joint shows as is red, swollen, hot, pain and moving obstacle, and joint deformity is more and more obvious, and patient's rheumatoid factor is often positive, and the X ray examination has significantly unusual performance.Secondly doctor trained in Western medicine mainly is an oral drug therapy to treatment of rheumatoid arthritis, and salicylic acid formulation example such as aspirin are drug of first choice, is indometacin, and Phenylbutazone and prednisone etc. are to end-stage patients' treatment that can undergo surgery.

Rheumatoid arthritis belongs to " arthromyodynia " scope in motherland's medical science, with the dampness removing collateral dredging, dispelling cold by warming the meridian is main, and prescription commonly used is a Radix Angelicae Pubescentis et Herba Taxilli Decoction.Theory of Chinese medical science is thought, the rheumatoid origin cause of formation is invaded outward owing to water is wet mostly, is felt ailment said due to cold or exposure again, or the diseases caused by exogenous pathogenic factor ailment said due to cold or exposure, it is wet to hold under the arm to hold concurrently, so that invasion of the body by blended pathogenic wind and dampness and falling ill is lingered on as rheumatism and is not removed to take place arthralgia, articular instability, or grain contracture, or disease such as apathy, and often with the passing of time delay forms chronic disease.

Patient with rheumatoid arthritis nearly all exists II-III level microcirculation disturbance and blood viscosity to increase.Rheumatoid arthritis belongs to traditional Chinese medical science arthromyodynia category, Pathogenesis of Rheumatoid Arthritis have inside and outside two because of.Endogenous cause of ill mainly contains innate deficiency, defends QI-insufficiency, or overworks, the healthy energy damage.Be that the said autoimmune function of modern medicine reduces.Exopathogenic factor mainly contains exopathogen invasion and attack bodies such as wind, cold, wet, heat, fights in QI and blood, must not declare logical, the multiple abscess joint.Therefore the primary disease deficient and excessive syndromes appearing together is intricate, forms vicious cycle, and its pain is delayed difficulty more to the bone.

In sum, diseases such as rheumatoid arthritis such as synovitis still do not have specific short in treatment.

Summary of the invention

Technical problem to be solved by this invention is, a kind of composition of medicine for the treatment of synovitis is provided, synergism by endo-medicine and liniment, utilize for oral administration and external application of Chinese herbal medicine to reach interior accent, hot compress, burn, stifling, infiltration is one, medicine is with molecularity, absorbed inside by human body respectively, the blood capillary of pore and expansion enters into the joint, tendon, ligament and surrounding tissue, promote partial microcirculation and blood circulation, strengthen part and even body's immunity, play expelling wind and removing dampness, dredge channels and activating collaterals, activating blood circulation to dissipate blood stasis, the effect of hard masses softening and resolving.

For solving the problems of the technologies described above, the invention discloses a kind of composition of medicine for the treatment of synovitis, form by endo-medicine and liniment,

In the described endo-medicine, the ratio of weight and number of various compositions is: Rhizoma Atractylodis 10-20 part, Cortex Phellodendri 10-20 part, Radix Stephaniae Tetrandrae 10-20 part, Fructus Chaenomelis 10-20 part, Cortex Acanthopancis 10-20 part, Radix Clematidis 10-20 part, Radix Angelicae Pubescentis 10-20 part, Radix Paeoniae Alba 10-20 part, Radix Astragali 30-60 part, Semen Coicis 30-60 part, Radix Codonopsis 30-60 part, Radix Angelicae Dahuricae 8-15 part, Ramulus Cinnamomi 8-15 part;

In the described liniment, the ratio of weight and number of various compositions is: Radix Aconiti Kusnezoffii 2-20 part, Radix Aconiti 5-10 part, Rhizoma Et Radix Notopterygii 5-20 part, Flos Carthami 5-10 part, Radix Saposhnikoviae 10-20 part, Ramulus Cinnamomi 5-10 part, Ramulus Mori 2-5 part, Rhizoma Atractylodis 5-10 part, Radix Aconiti Lateralis Preparata 10-20 part, Herba Epimedii 5-10 part, Herba speranskiae tuberculatae 10-20 part, Radix Angelicae Pubescentis 10-20 part, Radix Angelicae Dahuricae 10-20 part, Herba Asari 10-20 part.

In the described endo-medicine, the ratio of weight and number of various compositions is preferably: Rhizoma Atractylodis 15-18 part, Cortex Phellodendri 15-18 part, Radix Stephaniae Tetrandrae 15-18 part, Fructus Chaenomelis 15-18 part, Cortex Acanthopancis 15-18 part, Radix Clematidis 15-18 part, Radix Angelicae Pubescentis 15-18 part, Radix Paeoniae Alba 15-18 part, Radix Astragali 40-50 part, Semen Coicis 40-50 part, Radix Codonopsis 40-50 part, Radix Angelicae Dahuricae 10-12 part, Ramulus Cinnamomi 10-12 part.

In the described liniment, the ratio of weight and number of various compositions is preferably: Radix Aconiti Kusnezoffii 10-15 part, Radix Aconiti 8-10 part, Rhizoma Et Radix Notopterygii 10-15 part, Flos Carthami 8-10 part, Radix Saposhnikoviae 12-15 part, Ramulus Cinnamomi 8-10 part, Ramulus Mori 2-5 part, Rhizoma Atractylodis 8-10 part, Radix Aconiti Lateralis Preparata 10-15 part, Herba Epimedii 8-10 part, Herba speranskiae tuberculatae 15-20 part, Radix Angelicae Pubescentis 15-20 part, Radix Angelicae Dahuricae 15-20 part, Herba Asari 15-20 part.

When the liniment of described composition of medicine uses, various one-tenth should be placed in the enamel basin, add water 4000-5000ml, boil 20min and be placed under the knee joint affected part, the top uses bath towel or towel to cover, and utilizes steam to fumigate about 20min, use bath towel or towel soak affected part 20min instead after water temperature is suitable, every day twice, every dose of medicine was washed 2 days, and 10 days is a course of treatment.

When the endo-medicine of described composition of medicine uses, fry in shallow oil decoction and take, 1 dose of every day, decocting twice sub-service sooner or later, 10 days is a course of treatment.

Described composition of medicine in use, endo-medicine and liniment are used in combination; Take the endo-medicine decoction earlier, behind the 20min, use liniment.

The present invention treats the composition of medicine energy across-the-board regulation body's immunological function of synovitis, microcirculation improvement obstacle, removing toxic substances and promoting subsidence of swelling, dispelling cold by warming the meridian, expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling, treating both the principal and secondary aspects of a disease, all medicines share, the stasis of blood goes, wetly remove, heat is clear, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, patient's joint movement function recovered, by partial fumigating, hot compress, make the efficacy of a drug focus of going directly, obtained excellent curative.

The specific embodiment

The present invention treats the composition of medicine of synovitis, synergism by endo-medicine and liniment, utilize for oral administration and external application of Chinese herbal medicine to reach interior accent, hot compress, burn, stifling, infiltration is one, medicine is with molecularity, the blood capillary of absorbed inside, pore and expansion by human body enters into joint, tendon, ligament and surrounding tissue, promote partial microcirculation and blood circulation, strengthen part and even body's immunity, play expelling wind and removing dampness, dredge channels and activating collaterals, activating blood circulation to dissipate blood stasis, the effect of hard masses softening and resolving.

Wherein Ramulus Cinnamomi, Radix Saposhnikoviae, Rhizoma Et Radix Notopterygii, the Radix Angelicae Dahuricae are wind-cold-dispersing medicinal, and to deficiency of yang of liver and kidney, the instability of surface person can dispersing wind and cold, damp-clearing pain-relieving, easing joint movement, the Xin Wentong joint of loosing.The Radix Angelicae Dahuricae also has the logical effect of stealing of fragrance; Rhizoma Et Radix Notopterygii is controlled pain effect above the waist.Radix Aconiti is a warming the interior, and the narcotic analgesic medicine has antalgic, is good at expelling wind and removing dampness and removes cold and strong analgesic effect is arranged, and is used for the wind and cold temperature numbness due to yin-cold excess, numb limbs and tense tendons.Radix Aconiti Kusnezoffii is a drugs for dispelling internal cold, can search wind prevailing over dampness, and cold relieving is pursued expectorant, the sharp joint of warming the meridian network, the only pain numbness due to the pathogenic wind-warm pertinacious phlegm; Radix Aconiti, Radix Aconiti Kusnezoffii expelling wind and removing dampness, dispelling cold by warming the meridian have the narcotic analgesic effect, and " the Changsha medicine is separated " cloud: the Aconitum carmichjaelii Debx. warm-dryness syndrome is descending, and its property is dredged rapidly sharp, opens the pass natural fibre line of meat, and the power of expulsion cold-damp is very prompt, and all severe and migratory arthralgia all have good merit.Flos Carthami is a blood-regulating drug, promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing.The wet meridians that immerse of wind and cold hinder the mechanism of qi stagnation of QI and blood may bring about pain, control wind and control blood blood sector-style earlier from going out.Ramulus Mori is the dispelling wind and removing obstruction in the collateral medicine.Herba Epimedii has kidney invigorating and YANG supporting, strong muscle shape bone, sweet temperature compensation sun, the effect of hot temperature cold expelling.Mostly be insufficiency of kidney-YANG among the chronic pathogenic wind-warm patient greatly, performance often is the cold aversion to wind fear of cold of handkerchief, with the effective warming and recuperating the kidney-YANG of this medicine.Herba Epimedii reinforcing the kidney and supporting YANG, strengthening the tendons and bones, expelling wind and removing dampness, be to establish at the primary disease innate deficiency cause of disease, the effect of androgen sample is arranged, the expansion peripheral blood vessel is arranged again, increase the acra blood flow, improve circulation and more comprehensive immune pharmacological action, with the promotion body's immunity, improve lipid metabolism, the effect of removing superoxides and free radical has obvious relation.

Herba Asari expelling pathogenic wind from the body surface, dispersing cold for relieving pain can be controlled hundred joint contractures, and rheumatic arthralgia is cold to disperse yin channel, search to pick rheumatism of muscles and bones and make it to go out and pain relieving.The Radix Stephaniae Tetrandrae inducing diuresis to remove edema, expelling wind and removing dampness.The Cortex Acanthopancis qi and pathogen, the wind that promptly looses dehumidifies and strengthening the tendons and bones.The Semen Coicis invigorating spleen and kidney, removing damp and stopping pain.Rhizoma Atractylodis, Cortex Phellodendri medicine for rheumatism, heat clearing and damp drying.Radix Aconiti Lateralis Preparata extremely hot in nature, acrid in the mouth, logical 12 warps have the fiery recuperating depleted YANG of benefit, the cold expelling pain that wets, relieves the pain, and the key medicine of dispelling cold by warming the meridian and is dispersed the same usefulness of medicine, can dispel at the wind and cold of table by warm space between skin and muscles, and going into the warming YANG medicine can be first down, the trembling with fear in the lining of dispelling.The Radix Astragali, Radix Codonopsis: benefiting QI for strengthening the superficies, strengthening superficial resistance to stop perspiration, the invigorating the spleen and replenishing QI benefit is supported the day after tomorrow, call at " Japan hanako materia medica ": the Radix Astragali helps the gas strengthening bone and muscle, put on flesh and enrich blood ... modern pharmacological research confirms that body nonspecific immunity humoral immunization, cellular immunization are all had tangible regulating action, promotes the reticuloendothelial system phagocytic effect, improves immune status, increases the resistance of pernicious stimulation to external world.Radix Angelicae Pubescentis, Fructus Chaenomelis, Radix Clematidis dispelling, collateral-activating, wind-damp dispelling, the meridian dredging, expectorant saliva.According to " medicine justice ": Radix Clematidis, property are anxious suddenly, and lid is walked and do not kept, and the logical twelve channels and collaterals of a surname share sour and sweet drugs can transforme into YIN with the Radix Paeoniae Alba, yin nourishing hemorrhage, slow utmost point pain relieving.Radix Paeoniae Alba nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant.Record in " not Lu ": " the clear and coherent blood vessels of the Radix Paeoniae Alba, slow in, dispelling malignant blood, expelling extravasated blood, the gas that anhydrates, sharp bladder, intestine and small intestine, subduing inflammation, row cold and heat when (controlling), attacked by pestiferous factors stomachache, lumbago ".The Herba speranskiae tuberculatae expelling wind and removing dampness, Radix Aconiti Lateralis Preparata is joined in the detoxifcation pain relieving, removes severe and lingering illness, controls insensitive impediment and imitates especially; Herba speranskiae tuberculatae is joined Rhizoma Atractylodis, the dispelling the wind and dampness pathogens arthromyodynia, and a dampness is long partially, and a pain relieving is meritorious, and two medicine mutual reinforcements between are usefulness, damp-clearing pain-relieving, effect heightens.

Composition of medicine of the present invention in use, endo-medicine and liniment are used in combination; Take the endo-medicine decoction earlier, behind the 20min, use liniment.When liniment uses, various one-tenth should be placed in the enamel basin, add water 4000-5000ml, boil 20min and be placed under the knee joint affected part, the top uses bath towel or towel to cover, and utilizes steam to fumigate about 20min, use bath towel or towel soak affected part 20min instead after water temperature is suitable, every day twice, every dose of medicine was washed 2 days, and 10 days is a course of treatment.When endo-medicine uses, fry in shallow oil decoction and take, 1 dose of every day, decocting twice sub-service sooner or later, 10 days is a course of treatment.

Embodiment 1: Mrs He, and 60 years old, double knee joint pain was more than 6 years, and with the joint aversion to wind of being afraid of cold, knee joint swelling hydrops over nearly 2 years is gone up difficulty downstairs simultaneously, and the joint joint stuffiness is handicapped.Be diagnosed as senile osteoarthritis companion synovitis, use following prescription:

For oral administration: Rhizoma Atractylodis 10g, Cortex Phellodendri 10g, Radix Stephaniae Tetrandrae 20g, Fructus Chaenomelis 20g, Cortex Acanthopancis 10g, Radix Clematidis 10g, Radix Angelicae Pubescentis 10g, Radix Paeoniae Alba 10g, Radix Astragali 30g, Semen Coicis 60g, Radix Codonopsis 30g, Radix Angelicae Dahuricae 8g part, Ramulus Cinnamomi 8g part;

External application: Radix Aconiti Kusnezoffii 2g, Radix Aconiti 5g, Rhizoma Et Radix Notopterygii 20g, Flos Carthami 10g, Radix Saposhnikoviae 10g, Ramulus Cinnamomi 10g, Ramulus Mori 2g, Rhizoma Atractylodis 5g, Radix Aconiti Lateralis Preparata 10g, Herba Epimedii 5g, Herba speranskiae tuberculatae 20g, Radix Angelicae Pubescentis 10g, Radix Angelicae Dahuricae 10g, Herba Asari 10g.

Treatment once takes effect, and knee joint is afraid of that cool aversion to wind alleviates, Orally taken and externally 2 times, and patient promptly takes off knee cap and line trousers, can wear skirt.First course of treatment: patient's hydrarthrosis absorbs, and arthralgia obviously alleviates, and the massage of need not getting up evening can be fallen asleep.Second course of treatment: the patient is last downstairs freely, rises and sits freely, and it is brisk to walk; The 3rd course of treatment: after treatment.There was not recurrence in 12 months with anti-the observation.

Embodiment 2: Mr. Huang, 50 years old, because of two ankle joint red and swollen heat pains are diagnosed as the ankle joint synovitis by how tame hospital, use following prescription:

For oral administration: Rhizoma Atractylodis 15g, Cortex Phellodendri 15g, Radix Stephaniae Tetrandrae 15g, Fructus Chaenomelis 15g, Cortex Acanthopancis 15g, Radix Clematidis 15g, Radix Angelicae Pubescentis 15g, Radix Paeoniae Alba 15g, Radix Astragali 40g, Semen Coicis 40g, Radix Codonopsis 40g, Radix Angelicae Dahuricae 10g, Ramulus Cinnamomi 10g.

External application: Radix Aconiti Kusnezoffii 15g, Radix Aconiti 10g, Rhizoma Et Radix Notopterygii 15g, Flos Carthami 10g, Radix Saposhnikoviae 15g, Ramulus Cinnamomi 10g, Ramulus Mori 5g, Rhizoma Atractylodis 10g, Radix Aconiti Lateralis Preparata 10g, Herba Epimedii 10g, Herba speranskiae tuberculatae 20g, Radix Angelicae Pubescentis 20g, Radix Angelicae Dahuricae 20g, Herba Asari 20g.

Medication after 20 days symptom obviously alleviate, alleviate after 30 days, continue medication after 1 month, condition of illness disappears, so far recurrence.

Embodiment 3: woman with a hypoplastic vagina scholar, 52 years old, whole body arthritis, bitterly, 3-4 is surplus, take multiple antalgica for a long time, also do not taking antalgica when examining, looking into rheumatoid factor (+) through chemical examination, erythrocyte sedimentation rate speeds, anti-" O " is normal, deadlock is greater than 1 hour in morning in the morning, clinical diagnosis: rheumatoid arthritis, use following prescription:

For oral administration: Rhizoma Atractylodis 20g, Cortex Phellodendri 20g, Radix Stephaniae Tetrandrae 20g, Fructus Chaenomelis 20g, Cortex Acanthopancis 10g, Radix Clematidis 10g, Radix Angelicae Pubescentis 10g, Radix Paeoniae Alba 10g, Radix Astragali 30g, Semen Coicis 30g, Radix Codonopsis 30g, Radix Angelicae Dahuricae 10g, Ramulus Cinnamomi 10g;

External application: Radix Aconiti Kusnezoffii 10g, Radix Aconiti 10g, Rhizoma Et Radix Notopterygii 10g, Flos Carthami 10g, Radix Saposhnikoviae 10g, Ramulus Cinnamomi 10g, Ramulus Mori 2g, Rhizoma Atractylodis 5g, Radix Aconiti Lateralis Preparata 10g, Herba Epimedii 5g, Herba speranskiae tuberculatae 10g, Radix Angelicae Pubescentis 10g, Radix Angelicae Dahuricae 10g, Herba Asari 10g.

After with a course of treatment, effect is very remarkable, continues again to take orally, and external combines to treat and checks 3 courses of treatment again: rheumatoid factor and every index, all recover normal, and follow up a case by regular visits to and do not see recurrence in 2 years.

Embodiment 4: Mr. Zhao, 39 years old, the 8-9 that falls ill, repeatedly therapeutic effect is not good through various big hospital, and symptom is: double-legged arthroncus, pain, the swelling of both hands wrist, pain, and 37.5 ℃-39.50 ℃ of low grade fever of companion, it is normal that rheumatoid factor (+) anti-" O " is looked in chemical examination, erythrocyte sedimentation rate 78mm/ hour, meets the rheumatoid diagnostic criteria, clinical diagnosis: rheumatoid arthritis, use following prescription:

For oral administration: Rhizoma Atractylodis 15g, Cortex Phellodendri 15g, Radix Stephaniae Tetrandrae 15g, Fructus Chaenomelis 15g, Cortex Acanthopancis 15g, Radix Clematidis 15g, Radix Angelicae Pubescentis 15g, Radix Paeoniae Alba 15g, Radix Astragali 40g, Semen Coicis 40g, Radix Codonopsis 40g, Radix Angelicae Dahuricae 10g, Ramulus Cinnamomi 10g.

External application: Radix Aconiti Kusnezoffii 15g, Radix Aconiti 10g, Rhizoma Et Radix Notopterygii 15g, Flos Carthami 10g, Radix Saposhnikoviae 15g, Ramulus Cinnamomi 10g, Ramulus Mori 5g, Rhizoma Atractylodis 10g, Radix Aconiti Lateralis Preparata 15g, Herba Epimedii 10g, Herba speranskiae tuberculatae 20g, Radix Angelicae Pubescentis 20g, Radix Angelicae Dahuricae 20g, Herba Asari 20g.

Course of treatment of medication, clinical assay is every all normal, follows up a case by regular visits to and does not see recurrence in 3 years.

In 32 routine patient with rheumatoid arthritis, male's 15 examples, women's 17 examples; Between the age of onset 16 years old to 77 years old, wherein saw at most to 50 years old, account for 77% with 25 years old; The course of disease 1 year is with interior 9 examples, 1 to 5 year 12 example, 6 to 10 years 3 examples, 8 examples more than 10 years.Therapeutic outcome is cured 22 examples, effective 8 examples, invalid 2 examples, total effective rate 93.8%.Composition of medicine of the present invention came into effect in general 3 to 7 days, and medication was swollen and ache and obviously alleviated in 10 days, and medication was swollen and ache and disappeared substantially in 20 days, and joint movement function obviously improves, and medication can be located steady statue in 2 months, the general nothing recurrence in the back of stopping using.

Claims (3)

1. a composition of medicine for the treatment of synovitis is characterized in that, form by endo-medicine and liniment,

In the described endo-medicine, the ratio of weight and number of various compositions is: Rhizoma Atractylodis 10-20 part, Cortex Phellodendri 10-20 part, Radix Stephaniae Tetrandrae 10-20 part, Fructus Chaenomelis 10-20 part, Cortex Acanthopancis 10-20 part, Radix Clematidis 10-20 part, Radix Angelicae Pubescentis 10-20 part, Radix Paeoniae Alba 10-20 part, Radix Astragali 30-60 part, Semen Coicis 30-60 part, Radix Codonopsis 30-60 part, Radix Angelicae Dahuricae 8-15 part, Ramulus Cinnamomi 8-15 part;

In the described liniment, the ratio of weight and number of various compositions is: Radix Aconiti Kusnezoffii 2-20 part, Radix Aconiti 5-10 part, Rhizoma Et Radix Notopterygii 5-20 part, Flos Carthami 5-10 part, Radix Saposhnikoviae 10-20 part, Ramulus Cinnamomi 5-10 part, Ramulus Mori 2-5 part, Rhizoma Atractylodis 5-10 part, Radix Aconiti Lateralis Preparata 10-20 part, Herba Epimedii 5-10 part, Herba speranskiae tuberculatae 10-20 part, Radix Angelicae Pubescentis 10-20 part, Radix Angelicae Dahuricae 10-20 part, Herba Asari 10-20 part.

2. according to the composition of medicine of the described treatment synovitis of claim 1, it is characterized in that, in the described endo-medicine, the ratio of weight and number of various compositions is: Rhizoma Atractylodis 15-18 part, Cortex Phellodendri 15-18 part, Radix Stephaniae Tetrandrae 15-18 part, Fructus Chaenomelis 15-18 part, Cortex Acanthopancis 15-18 part, Radix Clematidis 15-18 part, Radix Angelicae Pubescentis 15-18 part, Radix Paeoniae Alba 15-18 part, Radix Astragali 40-50 part, Semen Coicis 40-50 part, Radix Codonopsis 40-50 part, Radix Angelicae Dahuricae 10-12 part, Ramulus Cinnamomi 10-12 part.

3. according to the composition of medicine of the described treatment synovitis of claim 1, it is characterized in that, in the described liniment, the ratio of weight and number of various compositions is: Radix Aconiti Kusnezoffii 10-15 part, Radix Aconiti 8-10 part, Rhizoma Et Radix Notopterygii 10-15 part, Flos Carthami 8-10 part, Radix Saposhnikoviae 12-15 part, Ramulus Cinnamomi 8-10 part, Ramulus Mori 2-5 part, Rhizoma Atractylodis 8-10 part, Radix Aconiti Lateralis Preparata 10-15 part, Herba Epimedii 8-10 part, Herba speranskiae tuberculatae 15-20 part, Radix Angelicae Pubescentis 15-20 part, Radix Angelicae Dahuricae 15-20 part, Herba Asari 15-20 part.