CN101193679B - Aspiration catheter - Google Patents
Aspiration catheter Download PDFInfo
- Publication number
- CN101193679B CN101193679B CN2006800202312A CN200680020231A CN101193679B CN 101193679 B CN101193679 B CN 101193679B CN 2006800202312 A CN2006800202312 A CN 2006800202312A CN 200680020231 A CN200680020231 A CN 200680020231A CN 101193679 B CN101193679 B CN 101193679B
- Authority
- CN
- China
- Prior art keywords
- catheter
- tubular element
- catheter shaft
- shaft
- tubular
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
- A61M25/008—Strength or flexibility characteristics of the catheter tip
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/06—Body-piercing guide needles or the like
- A61M25/0662—Guide tubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22038—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with a guide wire
- A61B2017/22039—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with a guide wire eccentric
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22082—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance
- A61B2017/22084—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance stone- or thrombus-dissolving
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M2025/0004—Catheters; Hollow probes having two or more concentrically arranged tubes for forming a concentric catheter system
- A61M2025/0006—Catheters; Hollow probes having two or more concentrically arranged tubes for forming a concentric catheter system which can be secured against axial movement, e.g. by using a locking cuff
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
- A61M25/008—Strength or flexibility characteristics of the catheter tip
- A61M2025/0081—Soft tip
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
- A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
- A61M25/0026—Multi-lumen catheters with stationary elements
- A61M25/0028—Multi-lumen catheters with stationary elements characterized by features relating to at least one lumen located at the proximal part of the catheter, e.g. alterations in lumen shape or valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
- A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
Abstract
An aspiration catheter system for aspirating and removing thrombi in blood vessel by inserting the catheter into the blood vessel having a catheter member and a catheter shaft wherein a tubular member of the catheter member is inserted into a tubular part of the catheter shaft, a distal end of the tubular member is projected out of a distal end of the tubular part of the catheter shaft to form an aspiration inlet of the thrombi, a proximal end of the tubular member is located in the catheter shaft, an inner space of the tubular member connects to an inner space of the catheter shaft, and thrombi is aspirated or drug solution is injected from a proximal part of the tubular part of the catheter shaft.
Description
Technical field
The present invention relates to be used for the conduit of blood vessel and relate to suction particularly and remove the refuse of blood vessel such as thrombosis or the conduit of injecting liquid drug in the blood vessel.
Background technology
Usually use suction catheter to remove thrombosis in the blood vessel etc.The operator is inserted into conduit in the blood vessel and moves along blood vessel and places the conduit to the target location simultaneously and sentence suction and remove thrombosis etc.The operator penetrates into conduit in the blood vessel and moves along blood vessel and places the conduit to the target location simultaneously and sentence suction and remove thrombosis etc.For example, patent document 1 hereinafter discloses a kind of suction catheter with dilator, it has double tubular structure and comprises having the center conduit and the outer catheter of diameter and length much at one, this conduit is usually through center conduit suction and remove thrombosis simultaneously when central conduit is stopped up by clot, this operator easily from outer catheter pull out center conduit with a suitable center conduit replacement it.Simultaneously this outer catheter itself also play conduit effect and can aspirate clots etc.But the center conduit of the device of patent document 1 has dilator, and this dilator reduces the effective diameter of this catheter suction, also has the conical depression that a flexibility is arranged at the dilator distal end place, and this recess constitutes the narrowest part of conduit and reduces aspiration.
[patent document 1] Japanese publication spy opens flat No.24058/95
Be both since during the catheter suction of patent document 2 ball expanded, so it can not move forward and backward in blood vessel in aspiration procedure.Thereby during the thrombosis in removing the extensive region be dispersed in blood vessel, frequent process with trouble is inevitably so that conduit repeat aspiration and motion in blood vessel.
[patent document 2] WO 02/087677
Summary of the invention
[by the problem to be solved in the present invention]
Because the suction catheter in the blood vessel is a surgical instruments, use this apparatus in the blood vessel and be directed to the damaged portion of blood vessel so that handle the inwall or the internal blood vessel of blood vessel by inserting by leading line etc., therefore usually so conduit must be made very carefully, for example, its overall diameter is less than 1 millimeter.In addition, be accumulated in the situation of the high thickness thrombosis use fine duct on the blood vessel in suction and removing, make even if just go wrong when swabbing pressure increases it become be difficult to or can not aspirate thrombi or may aspirate it also will be for a long time, the while, excessive burden was added on one's body the patient.Simultaneously in the situation of traditional suction catheter, be unable to estimate the draw resistance of the conduit total length that is loaded on the aspirator, because it is to install along the extended line of the nearside of the longitudinal axis of conduit.
But when using conduit in inserting blood vessel, there is the restriction of conduit rugosity, can not makes external diameter thicker basically simultaneously than traditional conduit.So the conduit that thrombosis keeps alap swabbing pressure simultaneously can be aspirated and remove to long-time exploration fast.In the situation of the conduit of this external above patent document 2, this conduit uses a ball and with this ball conduit is fixed on the inwall of blood vessel so that aspirate, be difficult to clear up clot in the extensive region in blood vessel rapidly, owing to be unable to estimate repeat aspiration and the motion of conduit in blood vessel.Because heavy-gravity clot adheres to the extensive region of blood vessel wall, so just make the conduit of patent document 2 will spend long-time these sticking clots of on extensive region, removing, so need frequent with busy process, long-time simultaneously the exploration obtains and can remove clot and can alleviate patient's burden in extensive region easily and fast.
[method of dealing with problems]
The present invention relates to a kind of suction catheter, wherein tubular element be positioned at the distally of catheter shaft and this catheter shaft self as at the suction tube at the tubular member nearside place of catheter shaft in case the effective diameter that obtains aspirating as far as possible near the overall diameter of conduit, set a Y shape union joint inhales so that increase pumping velocity by the length that shortens suction channel from the lateral axle of Y union joint by means of aspirator simultaneously in the proximal end of the tubular member of catheter shaft, in the suction channel of this shortening, produce draw resistance because be in a ratio of thin suction channel with traditional conduit, this conventional catheters does not have the conduit of ball can aspirate the thrombosis of extensive region in the blood vessel swimmingly because this conduit can aspirate while mobile conduit in blood vessel with the aspirator suction of the extension that is in catheter proximal end.
The catheter component that the present invention relates to suction catheter is in order to the useless refuse in suction and the removing blood vessel, such as thrombosis and/or logical conduit is inserted in the blood vessel drug injection in blood vessel, wherein pipe guide has catheter component and catheter shaft, this catheter component has flexible shaft, it have far-end and near-end simultaneously tubular element be connected to the far-end of flexible shaft, and the nearside inner chamber that is arranged in the tubular element of catheter shaft is connected to the chamber of the tubular member of catheter shaft.
The catheter component of the present invention that is configured to the part of conduit system comprises the flexible shaft with far-end and near-end, the hub that is connected to the tubular element of flexible shaft far-end and is connected to its near-end.The interior space of the near-end of tubular element is connected to the tubular member of catheter shaft.This flexible shaft is the axle that is connected with the operation hub with tubular element.Unrestricted on its cross sectional shape especially, preferably this shape is the part that a circular rod, circular cross-section shape are extended the tubular wall of tubular element, more preferably has the pole of the flexible difference in no orientation.Can use solid bar and tubular rods.In the situation of tubular rods, another surgical instruments can be inserted into tubular element also further in blood vessel through the tubular cavity of operation hub and flexible shaft.
This flexible shaft is connected to the near-end of tubular element and in order to the position of mobile tubular element in the tubular member of catheter shaft.Importantly the position of the catheter shaft of tubular element chamber in being inserted into flexible shaft of aspirate thrombi is connected in the interior space of catheter shaft.The method that many connections are arranged.Comparing in the situation with very little overall diameter with the interior space of catheter shaft, not having the sizable spatial flexible shaft of the inside is useful to seesawing of tubular element, though can make a space therein.In this case, the main space between the inside of the outside of the interior space of tubular element and flexible shaft and catheter shaft is connected.Also have when the overall diameter of flexible shaft is similar to the interior diameter of catheter shaft, just need be made for the space of suction or injection in the inside of flexible shaft.So just need be connected with the interior space of catheter shaft by means of the space with the flexible shaft the inside such as seam, otch, hole, mesh.Through the interior space of flexible shaft the space between inside the interior space of tubular element and flexible shaft outside and the catheter shaft is connected simultaneously.Normally 20 centimetres to 200 centimetres of the length of flexible shaft, and preferred 30 centimetres to 130 centimetres.The material of flexible shaft can be flexiplast or metal, for example, can use polyethylene, polyurethane, nylon, nylon rubber, ethane-acetic acid ethyenyl co-polymer, polyisoprene, poly-carbide, polystyrene, polyformaldehyde, acrylonitrile-styrene resin, m-polyphenylene oxide, polrvinyl chloride, polymethylene methacrylate, polyethylene terephthalate, polybutylene terepthatlate etc. and compositions thereof.Can preferably use metal material such as rustless steel and superelastic metal (Ni-Ti alloy).Can also use composite, it be with metal as core material and outside core material coated polymer and constituting.
Hub can be that Any shape makes the operator control this flexible shaft easily as far as possible, but too greatly or too heavy hub be that unaccommodated because catheter component is taken out the cleaning area possibly.When constituting tubular cavity in flexible shaft, the hole that is connected with the chamber can form in hub.In order to be connected, can constitute medical attraction circular cone or medical double star thread mechanism simultaneously with other apparatus.As material, can use polyethylene, polyurethane, nylon, nylon rubber, ethane-acetic acid ethyenyl co-polymer, polyisoprene, poly-carbide, polystyrene, polyformaldehyde, acrylonitrile-styrene resin, m-polyphenylene oxide, polrvinyl chloride, polymethylene methacrylate, polyethylene terephthalate, polybutylene terepthatlate etc. and compositions thereof.
The length of the tubular element of catheter component can be 3 centimetres to 50 centimetres usually, and preferred 5 centimetres to 15 centimetres.The overall diameter of tubular element is determined by the interior diameter of catheter shaft.Owing to use tubular element in the catheter shaft by being inserted into, the overall diameter that just needs tubular element enough near the interior diameter of catheter shaft so that blood does not leak into from the end of suction catheter member or medicinal liquid does not spill gap between tubular element and the catheter shaft, importantly between tubular element and catheter shaft, have little gap on the other hand, so so the motion of tubular element in catheter shaft without interruption in suction or injection work process the operator can often move catheter component at fore-and-aft direction.In fact, preferred gap is from 0.02% to 25% of the catheter shaft overall diameter that uses, and more preferably from 0.1% to 15%.The radial thickness of tubular element can be from 0.02 millimeter to 2 millimeters.
Optionally with the far-end of tubular element with near-end is cut sth. askew thereby move smoothly in tubular element is inserted into the process of the coupling part of catheter shaft or blood vessel or its contraction.For this oblique angle of length direction can be 5～70 degree, preferred 20～50 degree.The shape of cutting can be single collinear, comprise several collinear recombination lines or smooth camber line.Can make tubular element by homogenous material or composite.Can use polyethylene, nylon, nylon rubber, polyurethane, fluorocarbon resin, ethane-acetic acid ethyenyl co-polymer, silicon resin etc. as homogenous material.Can use material, two layer structure as composite.In such situation, can use fluorocarbon resin, polyamide, polyamide elastomer, polyethylene etc. as internal layer, can use polyethylene, polyurethane, nylon, nylon rubber, ethylene simultaneously---vinyl acetate co-polymer, silicon resin etc. are as outer.Can insert the thin slice (stiffener of net or spiral fiber form) of metal or resin
In the aspiration end of tubular element, thereby make a radiotransparen mark to prevent by of the decline of eyes observation tubular element from catheter shaft near the two cutting part of the opposite end of aspiration end and tubular element aspiration end.This mark can only be located to form at one of two ends.This mark can or form in radial thickness in surface, the inside of tubular element, and this mark can be shapes such as pipe, spiral, pigment, powder.Also can in whole tubular element material, mix material that X ray sees through so that under X ray, see whole tubular element.The material of this mark can be the material of any transmitted X-rays, and can use rustless steel, platinum, tungsten or its alloy and further contrast medium as subcarbonate, oxidation and barium sulfate.
Can carry out surface treatment to obtain lubricated character at the outer surface of tubular element so as to insert catheter shaft and the process of in blood vessel, moving in reduce resistance.Surface conditioning agent is can be the same polymer and the co-polymer of hydrophobic material such as fluorocarbon resin and silicon resin or hydrophilic material such as polyethylene glycol (PEG) polyethylene oxide (PEO), polyvinyl alcohol, polyacrylamide and methacrylate derivant simultaneously optionally.For further increasing lubricant effect, can handle at the inner surface of catheter shaft and the surface of tubular element.
Thrombosis from the far-end of tubular element suction blood vessel is transported to the inner chamber of catheter shaft from the near-end of tubular element, removes through the lateral of Y union joint by means of aspirator simultaneously.
Though the inner chamber of tubular element can be as the passage of leading line, preferred fabrication independently path is used for leading line.Like this, the position of leading line path can be any part facing to tubular element, but preferred tubular element may only form path simultaneously in the whole length of length direction near aspiration end.Though guide wire channel can be made in the overall diameter outside of tubular element, preferably be made in guide wire channel in the radial thickness or the overall diameter of tubular element in the cross sectional shape that keeps the tubular element circle to prevent blood between catheter shaft and the tubular element and flow into and the outflow of medicinal liquid.Guide wire channel can may be made or independently make simultaneously by making with the tubular element identical materials with tubular element integral body, also a part or whole part of guide wire channel may be made in the space of tubular element.Suitably select the interior diameter of guide channel according to the leading line diameter that will use, and can be 0.1 millimeter to 3 millimeters.This guide wire channel can be made in flexible shaft the inside or flexible shaft outside independently, perhaps may not do guide wire channel especially after the near-end that takes out tubular element.
This guide wire channel can be stretched out the aspiration end of tubular element, and suitable extension elongation can be 0.3 millimeter to 10 millimeters simultaneously, and preferred 0.5 millimeter to 4 millimeters.The length of guide wire channel comprises that extension elongation can be 5 millimeters to 500 millimeters, and is preferably 10 millimeters to 300 millimeters.
Its diameter is from 0.1 millimeter to 3 millimeters in the time of the cross sectional shape circular of guide wire channel, simultaneously when being used for coronary artery especially preferably from 0.3 millimeter to 1 millimeter.The radial thickness of guide wire channel can be 0.02 millimeter to 2 millimeters when the individual member that forms from tubular element, is preferably 0.05 millimeter to 0.25 millimeter when being used for coronary artery.Material can be single or composite in this case.As homogenous material, can use polyethylene, nylon, nylon rubber, polyurethane, fluorocarbon resin, ethylene---vinyl acetate co-polymer, silicon resin etc.As composite, can use material, two layer structure.In this case, internal layer as composite can use fluorocarbon resin, polyamide, polyamide elastomer, polyethylene etc., and can use polyethylene, polyurethane, nylon, nylon rubber, ethylene as the skin of composite---vinyl acetate co-polymer, silicon resin etc.
Be independent of in the most advanced and sophisticated situation of guide wire channel of tubular element in formation, can carry out surface treatment with lubrication property that most advanced and sophisticated outside is provided so that in inserting catheter shaft or its process of in blood vessel, moving, reduce resistance.This surface conditioning agent is optionally simultaneously can be hydrophobic material such as fluorocarbon resin and silicon resin or hydrophilic material such as polyethylene glycol (PEG), polyethylene oxide (the same polymer and the co-polymer of PEO, polyvinyl alcohol, poly-propionic acid amide. and methacrylate derivant.
Preferably monitor the position of flexible shaft with X ray image from safety point of view.Contrast medium such as tungsten, carbonic acid, oxidation and barium sulfate can be mixed in the material special in the situation of the material that contains resin, at the mark that can do transmitted X-rays from the tip of the extension of the guide wire channel of aspiration end.This mark can form in surface, inner surface or the radial thickness of the flexible shaft of shapes such as pipe, spiral, pigment, powder.The material of mark can be the material of aforesaid any transmitted X-rays.
Can use commercial product can select its rugosity for use according to the rugosity of the blood vessel that inserts conduit therein simultaneously as leading line.The leading line that is used to have rugosity blood vessel such as 0.012,0.014,0.018,0.025,0.035 inch is commercially available.Usually use the leading line of 0.014 inch rugosity for the coronary artery of heart.From 30 centimetres to 300 centimetres different lengths is commercially available.Usually use from 175 centimetres to 190 centimetres or 300 centimetres length for heart arter.They were designed to ganoid so that blood vessel is not directed to the tip injury of line when the conduit with different structure was possible.Such as those as stainless wire coil total length on the leading line that forms, a kind of metal wire that 30 cm coil are arranged at far-end, this far-end initially is inserted in the blood vessel, and those are possible by composite such as rustless steel and superelastic alloy (Ni-Ti alloy) leading line that make and those coating polyethylenes or nylon polymer.Can control leading line with guiding catheter in blood vessel.
Catheter shaft of the present invention is tubular and has approximate uniform cross sectional shape and approximate uniform area of section.Tubular element is arranged on catheter shaft when catheter shaft is used for the conduit of blood vessel as mentioned above.The far-end of the extended catheter shaft of this tubular element, but need the near-end of this tubular element often to remain in the catheter shaft.Though special-purpose conduit can be used as catheter shaft, commercial guiding catheter, injection of contrast agent also can use with the conduit diagnosed etc.Diameter is arranged is 3Fr to 10Fr and effective length is 90 centimetres to 120 centimetres conduit, and it is stable in blood vessel that various distal end shape so conduit are arranged simultaneously.There is product, for example a Jadkins left side, the Jadkins right side, the Amplazt right side, an Amplatz left side, Border, Multipurpose, Kimney, Champt etc. with curvature.
In the structure of dedicated conduits axle, to bending gradually the tubular portion of deliquescing have far-end and near-end and be the distal side formation of the catheter shaft of the joint that is connected with the coupling part, proximal end.The overall diameter of tubular element is can use 1 millimeter to 3.5 millimeters from 0.3 millimeter to 12 millimeters to coronary artery.Radial thickness can be 0.03 millimeter to 2 millimeters while can use 1 millimeter to 3.5 millimeters for coronary artery.Radial thickness can be 0.03 millimeter to 2 millimeters and to coronary artery preferred 0.05 millimeter to 0.8 millimeter.This tubular element can be made by homogenous material or composite.As homogenous material, can use polyethylene, nylon, nylon rubber, polyurethane, fluorocarbon resin (FEP, PTFE, PFA, PVDF etc.), stainless steel tube, superelastic alloy (Ni-Ti alloy) etc. and make composite, can use material, two layer structure.In this situation, as the internal layer of composite, can use fluorocarbon resin, polyamide, polyamide elastomer, polyethylene etc., and, can use polyethylene, polyurethane, nylon, nylon rubber etc. as the skin of composite.Preferably between internal layer and skin, insert sheet metal (member of net or spiral fiber form) or resin blade retention properties with the shape of the antitorque knot character of improving pipe or pipe.
The tubular portion of catheter shaft has and can contain tubular element and interior diameter that also be similar to the tubular element overall diameter.The hardness of tubular portion is uniformly as a complete unit or can gradually changes and boundlessness.Also may be with more than two ladder ground stepped change.An example of firmness change is such: be formed with the tubular portion of the nearside of uniform rigidity, form the tube in distally simultaneously, this distally is softening gradually towards the distally from its nearside.Tubular portion length with hardness of variation is not more than 35% of catheter shaft effective length usually, and the effective length of this catheter shaft is the total length of tubular portion and tubular portion.Normally 70 centimetres to 130 centimetres of the effective lengths of catheter shaft.
This tubular portion can be made by homogenous material or composite.For homogenous material, can use polyethylene, nylon, nylon rubber, polyurethane, fluorocarbon resin, ethylene---vinyl acetate co-polymer, silicon resin etc.For composite, can use material, two layer structure.In this case, for inner layer material, can use fluorocarbon resin, polyamide, polyamide elastomer, polyethylene etc., and, can use polyethylene, polyurethane, nylon, nylon rubber, ethylene as cladding material---vinyl ethyl ester co-polymer, silicon resin etc.Can between internal layer and skin, insert the sheet (stiffener of net or spiral fiber form) of metal or resin.
Use union joint with control catheter shaft self and in order to being connected to the coupling part, thus simultaneously within it portion have a space and keep the overall diameter of diameter greater than tubular element.Profile can select to consider simultaneously to be easy to handle and be connected to the connectivity of coupling part.Material as this union joint, can adopt poly-carbide, polystyrene, polyformaldehyde, acrylonitrile---styrene copolymerized compound, m-polyphenylene oxide, poly-ammonia vinyl chloride, polymethylene first acrylate, polyethylene terephthalate, polybutylene terepthatlate etc., but thereby the light material of preferred weight prevents that catheter shaft from coming off from patient.
Can carry out surface treatment to provide the lubricating property on the catheter shaft outer surface so that insert the process minimizing resistance of blood vessel at catheter shaft.Surface treatment method is optionally and can uses the homopolymer and the coenosarc polymers of hydrophobic material such as fluorocarbon resin and silicon resin or hydrophilic material such as polyethylene glycol (PEG), polyethylene oxide (PEO), polyvinyl alcohol, polypropylene amine and methacrylate derivant.
Use is connected to the Y union joint of catheter shaft to separate flexible shaft from aspirator with leading line and in order to be connected them to the outside as the coupling part.Flexible shaft is to pass through lateral to being connected of aspirator by main pipeline with leading line usually simultaneously, is possible though oppositely connect.
Aspirator in the present invention is optionally not limit especially simultaneously, and can adopt the aspirator such as injection-type and suction pump type.
Example
Fig. 1 represents an example of the present invention of conduit system 1, uses this conduit system 1 with aspirate thrombi and/or with injecting liquid drug by being inserted in the blood vessel in blood vessel.The figure shows whole conduit system 1 the figure shows catheter component 13 simultaneously and is inserted into state in the catheter shaft 4.These catheter component 13 (not shown)s comprise tubular element 3, flexible shaft 6, hub 7 and guide wire channel 10 shown in Figure 3.Coupling part between tubular element 3 and the flexible shaft 6 is represented in the tubular portion of catheter shaft 4 and not.Coupling part 5 is that the Y union joint while flexible shaft 6 of Fig. 1 passes trunk line 11.Flexible shaft 6 is used round bar type.Leading line 2 also can pass trunk line 11 and pass the trunk line 11 of Y union joint in Fig. 1.Aspirator 8 is connected to lateral 12.
The far-end of leading line 2 stretches out tubular element 3 and guide wire channel 10, and the near-end of leading line 2 stretches out from the Y union joint simultaneously.Suction opening 9 is the far-ends at tubular element 3.
The actual use example of the conduit in order to aspirate thrombi of the present invention below will be described.At first in the in-position of health, by an introducer that is called sheath by make the path that an aperture is determined to tremulous pulse through skin, for example, at wrist or near the inguinal zone of femur zone root; The tubular portion that comprises the catheter shaft 4 of commercially available leading line 2 advances near the target area through the hemorrhage valve of sheath introducer.
Near this target area, only leading line 2 pro-are to guarantee the path of medical care.Simultaneously rough A/C axle 4 after the position of leading line 2, this leading line pass the guide wire channel 10 of catheter component 13 and catheter component 13 are advanced near the thrombosis between the far-end of the tubular portion of the far-end of zone such as the leading line 2 of target and catheter shaft 4.This leading line 2 before catheter component 13 to prevent that leading line 2 from falling.Interior dress hemorrhage valve in the trunk line of coupling part 5 cuts out a little to minimize the leakage of blood simultaneously.The part that needs in addition is connected to near-end as 12 while of the lateral aspirator 8 that prolongs pipe and stop valve and be connected to coupling part 5.After the layout of suction system 1 has been finished, use pressure that aspirator 8 applies reduction to this system 1 with aspirate thrombi, perhaps apply an elevated pressure so as after medicinal liquid that filling needs to be in the aspirator liquid medicine injection.This catheter component 13 is moved in the blood vessels to approximate target area with aspirate thrombi or liquid medicine injection and keeps the pressure or the elevated pressure of reduction with treatment simultaneously.
Though the shape of flexible shaft 6 is optionally, it can make axle simple solid cylindrical as shown in Figure 5 or hollow as shown in Figure 7 cylindrical.Also the part of flexible shaft that may be nearer than the near-end of the tubular element 3 in the catheter shaft 4 can have at external diameter that the hole on its integral body or the part or narrow slit make flexible shaft simultaneously and is connected so that be connected at the tubular portion 4 of conduit in the interior space of the interior space of catheter shaft 4 and tubular element 3 under the interior spatial condition of tubular element 3 of catheter component as shown in Figure 8 near the internal diameter of catheter shaft.
Connecting device is optionally and various ways arranged, and for example, forms a plurality of narrow slits as shown in figure 11 on the integral body of flexible shaft 6 or a part, and has difform several hole and replace narrow groove as shown in figure 13.The size in this hole can be identical or different or these holes is mixed.Figure 12 represents the figure of flexible shaft 6, and Zhou part or total length are vertically being cut in the figure.This flexible shaft 6 is not limited to one, for example, has many flexible shafts 6 as shown in Figure 9.In the situation of many flexible shafts, this axle can be integrated shown in Fig. 9 or 10 at selectable location.In this case, must consider that the position at hemorrhage valve trunk line 11 places of 5 in the coupling part is designed, and not from its leakage of blood.From the viewpoint of safety preferably by X ray image to monitor the position of flexible shaft.When the material that contains resin is used for flexible shaft, preferably mix contrast medium such as tungsten, basic carbonate, oxidation and barium sulfate.
Description of drawings
[Fig. 1] suction catheter of the present invention.
The catheter component of the suction catheter of [Fig. 2] Fig. 1.
The cutaway view of the A-A section of [Fig. 3] Fig. 1.Stretch out the section of the tubular element of catheter shaft, in tubular wall, constitute guide wire channel 10 simultaneously this leading line pass wherein.
The B-B section shape of [Fig. 4] Fig. 1.Tubular element is inserted in the catheter shaft.The part of tubular element constitutes guide wire channel with the identical while of Fig. 3 in tubular wall and this leading line passes wherein.
The C-C section shape of [Fig. 5] Fig. 1.There is not guide wire channel while leading line in interior space.
The profilograph of [Fig. 6] suction system of the present invention has been drawn a flexible shaft.
The profilograph of [Fig. 7] suction system of the present invention has been drawn a flexible shaft.
The profilograph of [Fig. 8] suction system of the present invention has been drawn a flexible shaft.
[Fig. 9] drawn the profilograph of the aspiration catheter system of the present invention of three flexible shafts in the proximal end of flexible shaft.
[Figure 10] drawn the profilograph of the aspiration catheter system of the present invention of three flexible shafts in the proximal end of flexible shaft.
The profilograph of [Figure 11] aspiration catheter system of the present invention has been drawn a flexible shaft.
[Figure 12] aspiration catheter system of the present invention has been drawn a flexible shaft.
[Figure 13] aspiration catheter system of the present invention has been drawn a flexible shaft.
Denotational description
1---conduit system, 2---leading line, 3---tubular element, 4---the tubular portion of catheter shaft, 5---the coupling part, 6---flexible shaft, 7---hub, 8---aspirator, 9---aspiration end, 10---guide wire channel, 11---trunk line, 12---lateral, 13---catheter component.
Claims (23)
1. one kind is used for aspirating and removing the thrombosis of blood vessel or by conduit being inserted into the aspiration catheter system of liquid medicine injection in the blood vessel, it has catheter component and catheter shaft, wherein the tubular element of catheter component is inserted into the tubular portion of catheter shaft, the far-end that the far-end of tubular element stretches out the tubular portion of catheter shaft enters the mouth with thrombosed suction, the near-end of tubular element is in the tubular portion of catheter shaft, the interior space of tubular element is connected with the interior space of the tubular portion of catheter shaft, from the proximal part aspirate thrombi or the liquid medicine injection of the tubular portion of catheter shaft, conduit can move in blood vessel when aspirate thrombi or liquid medicine injection simultaneously.
2. aspiration catheter system according to claim 1 is characterized in that, has the coupling part that is connected to aspirator at the proximal part of the tubular portion of catheter shaft.
3. aspiration catheter system according to claim 2 is characterized in that, the coupling part is that Y union joint while aspirator or injection device are connected to the lateral of Y union joint or are responsible for pipeline.
4. according to any described aspiration catheter system of claim 1 to 3, it is characterized in that this conduit has leading line and with the guide wire channel of this leading line that leads.
5. aspiration catheter system according to claim 4 is characterized in that this guide wire channel constitutes on the tubular wall of tubular element.
6. aspiration catheter system according to claim 4 is characterized in that, this leading line is extended on the far-end of tubular element.
7. according to any described aspiration catheter system of claim 1 to 3, it is characterized in that the far-end of tubular element forms a mark.
8. according to any described aspiration catheter system of claim 1 to 3, it is characterized in that, tubular element each outer surface at least and the tubular portion of catheter shaft through lubricated.
9. according to any described aspiration catheter system of claim 1 to 3, it is characterized in that the overall diameter of described tubular element is determined by the interior diameter of described catheter shaft.
10. according to any described aspiration catheter system of claim 1 to 3, it is characterized in that, the gap between the overall diameter of described tubular element and the interior diameter of described catheter shaft be described catheter shaft overall diameter 0.02% to 25%.
11. aspiration catheter system according to claim 10 is characterized in that, described gap be described catheter shaft overall diameter 0.1% to 15%.
12. one kind is used for aspirating and removing thrombosis or pass through to insert the catheter component of conduit to the aspiration catheter system of blood vessel liquid medicine injection from blood vessel, this system has catheter component and catheter shaft, wherein this catheter component has flexible shaft, this flexible shaft has far-end and near-end, hub is positioned at the proximal end and tubular element is positioned at the far-end of flexible shaft, simultaneously when tubular element is arranged in the tubular portion of catheter shaft, the inner chamber of tubular element is connected with the inner chamber of the tubular portion of catheter shaft, and conduit can move in blood vessel when aspirate thrombi or liquid medicine injection.
13. catheter component according to claim 12 is characterized in that, described catheter component has guide wire channel in order to the guiding leading line.
14. catheter component according to claim 13, wherein guide wire channel constitutes on the tubular wall of tubular element.
15. catheter component according to claim 13 is characterized in that, leading line is extended on the far-end of tubular element.
16. any described catheter component according to claim 12 to 14 is characterized in that, at the far-end formation mark of this tubular element.
17. any described catheter component according to claim 12 to 14 is characterized in that, the outer surface at least of this tubular element is through lubricated.
18. any described catheter component according to claim 12 to 14 is characterized in that, the overall diameter of described tubular element is determined by the interior diameter of described catheter shaft.
19. any described catheter component according to claim 12 to 14 is characterized in that, the gap between the overall diameter of described tubular element and the interior diameter of described catheter shaft be described catheter shaft overall diameter 0.02% to 25%.
20. catheter component according to claim 19 is characterized in that, described gap be described catheter shaft overall diameter 0.1% to 15%.
21. one kind is used for aspirating and remove the thrombosis of blood vessel or by conduit being inserted into the aspiration catheter system of liquid medicine injection in the blood vessel, described aspiration catheter system comprises:
Catheter component, it has tubular element, and wherein, described tubular element has near-end, far-end and interior space; With
Catheter shaft, it has tubular portion, and wherein, described tubular portion has proximal part, far-end and interior space;
Wherein, the overall diameter of described tubular element is determined by the interior diameter of described catheter shaft, the tubular element of described catheter component is inserted into the tubular portion of described catheter shaft, the far-end that the far-end of described tubular element stretches out the tubular portion of described catheter shaft enters the mouth with thrombosed suction, the near-end of tubular element is in the tubular portion of catheter shaft, the interior space of tubular element is connected with the interior space of the tubular portion of catheter shaft, from the proximal part aspirate thrombi or the liquid medicine injection of the tubular portion of catheter shaft, conduit can move in blood vessel when aspirate thrombi or liquid medicine injection simultaneously.
22. aspiration catheter system according to claim 21 is characterized in that, the gap between the overall diameter of described tubular element and the interior diameter of described catheter shaft be described catheter shaft overall diameter 0.02% to 25%.
23. aspiration catheter system according to claim 22 is characterized in that, described gap be described catheter shaft overall diameter 0.1% to 15%.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005168877A JP4549933B2 (en) | 2005-06-08 | 2005-06-08 | Vascular catheter |
| JP168877/2005 | 2005-06-08 | ||
| PCT/JP2006/311973 WO2006132434A1 (en) | 2005-06-08 | 2006-06-08 | Aspiration catheter |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011101057696A Division CN102205161B (en) | 2005-06-08 | 2006-06-08 | Aspiration catheter |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101193679A CN101193679A (en) | 2008-06-04 |
| CN101193679B true CN101193679B (en) | 2011-06-15 |
Family
ID=37498613
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011101057696A Expired - Fee Related CN102205161B (en) | 2005-06-08 | 2006-06-08 | Aspiration catheter |
| CN2006800202312A Expired - Fee Related CN101193679B (en) | 2005-06-08 | 2006-06-08 | Aspiration catheter |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011101057696A Expired - Fee Related CN102205161B (en) | 2005-06-08 | 2006-06-08 | Aspiration catheter |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1890756A4 (en) |
| JP (1) | JP4549933B2 (en) |
| CN (2) | CN102205161B (en) |
| CA (1) | CA2609966C (en) |
| WO (1) | WO2006132434A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE202017105494U1 (en) | 2017-09-11 | 2017-09-25 | Henan YADU Industry Co., Ltd. | Thrombus-aspiration catheter |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5347425B2 (en) * | 2008-10-23 | 2013-11-20 | ニプロ株式会社 | Thrombus suction catheter assembly |
| CN102551842B (en) * | 2010-12-24 | 2016-03-02 | 刘衍民 | Hard mirror stone taking device |
| JP5913856B2 (en) * | 2011-08-01 | 2016-04-27 | 株式会社グッドマン | Catheter and method for manufacturing catheter |
| JP5890979B2 (en) * | 2011-08-01 | 2016-03-22 | 株式会社グッドマン | Suction catheter |
| EP4101399A1 (en) | 2011-08-05 | 2022-12-14 | Route 92 Medical, Inc. | System for treatment of acute ischemic stroke |
| JP5783637B2 (en) * | 2012-11-28 | 2015-09-24 | 朝日インテック株式会社 | Suction catheter and suction catheter assembly |
| US9265512B2 (en) | 2013-12-23 | 2016-02-23 | Silk Road Medical, Inc. | Transcarotid neurovascular catheter |
| CN104323823B (en) * | 2014-11-20 | 2017-06-06 | 河南亚都实业有限公司 | A kind of thrombus suction catheter system |
| US10426497B2 (en) | 2015-07-24 | 2019-10-01 | Route 92 Medical, Inc. | Anchoring delivery system and methods |
| WO2016126974A1 (en) | 2015-02-04 | 2016-08-11 | Route 92 Medical, Inc. | Rapid aspiration thrombectomy system and method |
| US11065019B1 (en) | 2015-02-04 | 2021-07-20 | Route 92 Medical, Inc. | Aspiration catheter systems and methods of use |
| KR101712733B1 (en) * | 2015-06-23 | 2017-03-06 | 한양대학교 에리카산학협력단 | Robot for Vascular Intervention and System thereof |
| CN113350659A (en) * | 2016-02-24 | 2021-09-07 | 禾木（中国）生物工程有限公司 | Neurovascular catheter with enhanced flexibility |
| US10368885B2 (en) * | 2016-03-04 | 2019-08-06 | Well Lead Co., Ltd. | Suction evacuation sheath |
| US11266814B2 (en) * | 2016-08-10 | 2022-03-08 | Nipro Corporation | Support catheter |
| CN114984407A (en) | 2017-01-10 | 2022-09-02 | 92号医疗公司 | System, catheter and catheter advancement device for performing medical procedures in intracranial vessels |
| US10512756B2 (en) | 2017-01-12 | 2019-12-24 | Cardiac Dimensions Pty. Ltd. | Sizing catheters |
| CN107468306A (en) * | 2017-08-15 | 2017-12-15 | 南京普微森医疗科技有限公司 | A kind of thrombus suction catheter |
| CN107595332B (en) * | 2017-09-28 | 2020-11-03 | 华中科技大学鄂州工业技术研究院 | Endoscope for injection |
| CN107639086B (en) * | 2017-10-31 | 2023-03-28 | 深圳盛航科技有限公司 | Liquid knife |
| CN115999019A (en) | 2018-05-17 | 2023-04-25 | 92号医疗公司 | Aspiration catheter system and method of use |
| US11471582B2 (en) | 2018-07-06 | 2022-10-18 | Incept, Llc | Vacuum transfer tool for extendable catheter |
| CN109044484A (en) * | 2018-07-26 | 2018-12-21 | 河南亚都实业有限公司 | A kind of conduit of manual aspirate thrombi |
| US11766539B2 (en) | 2019-03-29 | 2023-09-26 | Incept, Llc | Enhanced flexibility neurovascular catheter |
| US11452841B2 (en) | 2019-04-11 | 2022-09-27 | Covidien Lp | Aspiration catheter system |
| CA3162704A1 (en) | 2019-12-18 | 2021-06-24 | Imperative Care, Inc. | Methods and systems for treating venous thromboembolic disease |
| CN112057133B (en) * | 2020-09-15 | 2021-10-15 | 玮铭医疗器械(上海)有限公司 | Multifunctional treatment catheter |
| CN116212210A (en) * | 2021-12-06 | 2023-06-06 | 先健科技(深圳)有限公司 | Suction catheter and preparation method thereof |
| WO2023103996A1 (en) * | 2021-12-06 | 2023-06-15 | 先健科技(深圳)有限公司 | Aspiration catheter and preparation method therefor |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2049956U (en) * | 1989-07-28 | 1989-12-27 | 王东亚 | Guide tube for removing thrombus in blood vessel |
| CN1285763A (en) * | 1998-01-30 | 2001-02-28 | 钟渊化学工业株式会社 | Balloon catheter, catheter shaft used for the catheter and method of production of balloon |
| WO2002087677A2 (en) * | 2001-05-01 | 2002-11-07 | Velocimed, L.L.C. | Emboli protection devices and related methods of use |
| CN2604196Y (en) * | 2002-12-26 | 2004-02-25 | 山东省医疗器械研究所 | Superlubricating intravascular introducing therapeutic catheter |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE170383T1 (en) * | 1993-06-24 | 1998-09-15 | Schneider Europ Gmbh | ASPIRATION CATHETER ASSEMBLY |
| US6004328A (en) * | 1997-06-19 | 1999-12-21 | Solar; Ronald J. | Radially expandable intraluminal stent and delivery catheter therefore and method of using the same |
| WO2002038198A2 (en) * | 2000-11-03 | 2002-05-16 | The Cleveland Clinic Foundation | Catheter for removal of solids from surgical drains |
| JP2002282349A (en) * | 2001-03-28 | 2002-10-02 | Nippon Zeon Co Ltd | Lubricative medical instrument and manufacturing method therefor |
| US7604612B2 (en) * | 2001-05-01 | 2009-10-20 | St. Jude Medical, Cardiology Division, Inc. | Emboli protection devices and related methods of use |
| JP4321019B2 (en) * | 2002-08-01 | 2009-08-26 | 株式会社カネカ | Suction catheter |
| JP4409179B2 (en) * | 2003-01-22 | 2010-02-03 | ニプロ株式会社 | Thrombus aspiration catheter with improved suction and crossability |
-
2005
- 2005-06-08 JP JP2005168877A patent/JP4549933B2/en not_active Expired - Fee Related
-
2006
- 2006-06-08 CA CA2609966A patent/CA2609966C/en not_active Expired - Fee Related
- 2006-06-08 CN CN2011101057696A patent/CN102205161B/en not_active Expired - Fee Related
- 2006-06-08 WO PCT/JP2006/311973 patent/WO2006132434A1/en active Application Filing
- 2006-06-08 CN CN2006800202312A patent/CN101193679B/en not_active Expired - Fee Related
- 2006-06-08 EP EP06747300A patent/EP1890756A4/en not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2049956U (en) * | 1989-07-28 | 1989-12-27 | 王东亚 | Guide tube for removing thrombus in blood vessel |
| CN1285763A (en) * | 1998-01-30 | 2001-02-28 | 钟渊化学工业株式会社 | Balloon catheter, catheter shaft used for the catheter and method of production of balloon |
| WO2002087677A2 (en) * | 2001-05-01 | 2002-11-07 | Velocimed, L.L.C. | Emboli protection devices and related methods of use |
| CN2604196Y (en) * | 2002-12-26 | 2004-02-25 | 山东省医疗器械研究所 | Superlubricating intravascular introducing therapeutic catheter |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE202017105494U1 (en) | 2017-09-11 | 2017-09-25 | Henan YADU Industry Co., Ltd. | Thrombus-aspiration catheter |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102205161B (en) | 2013-02-20 |
| CA2609966C (en) | 2013-08-13 |
| WO2006132434A1 (en) | 2006-12-14 |
| CN101193679A (en) | 2008-06-04 |
| JP4549933B2 (en) | 2010-09-22 |
| EP1890756A1 (en) | 2008-02-27 |
| CA2609966A1 (en) | 2006-12-14 |
| JP2006340868A (en) | 2006-12-21 |
| EP1890756A4 (en) | 2011-05-04 |
| CN102205161A (en) | 2011-10-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101193679B (en) | Aspiration catheter | |
| US11766539B2 (en) | Enhanced flexibility neurovascular catheter | |
| EP1246660B1 (en) | Anti-recoil catheter | |
| JP2589967B2 (en) | Catheter with atraumatic drug delivery tip | |
| EP0547463B1 (en) | Catheter introducer assembly | |
| DE60310166T2 (en) | Catheter and medical tube | |
| US20070073271A1 (en) | Catheter for diagnostic imaging and therapeutic procedures | |
| US20120271231A1 (en) | Aspiration thrombectomy device | |
| US5324276A (en) | Device and method for inhibiting intravascular device associated infection | |
| JP2008510513A (en) | Aspiration catheter with follower | |
| US20060184098A1 (en) | Subarachnoid spinal catheter for transporting cerebrospinal fluid | |
| US20140194857A1 (en) | Catheter with an enhanced pushability | |
| KR930010960B1 (en) | Medical guiding micro-tube | |
| JPH0385179A (en) | Medical balloon catheter | |
| US9750517B2 (en) | Method of aspirating a thrombus accumulation between a venous valve and a vein wall | |
| CN217724321U (en) | Medical catheter | |
| JP5112466B2 (en) | Catheter system | |
| JPH0434914B2 (en) | ||
| JPH11276592A (en) | Catheter and medical tube | |
| JP2002291902A (en) | Medical instrument insertion tool | |
| WO2023236743A1 (en) | Medical catheter | |
| JPH1176413A (en) | Catheter | |
| JP2002291868A (en) | Thrombus aspirator |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20110615 Termination date: 20190608 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |