CN101164608A - Traditional Chinese medicine composition for treating high blood pressure and preparation process thereof - Google Patents
Traditional Chinese medicine composition for treating high blood pressure and preparation process thereof Download PDFInfo
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- CN101164608A CN101164608A CNA2007101653221A CN200710165322A CN101164608A CN 101164608 A CN101164608 A CN 101164608A CN A2007101653221 A CNA2007101653221 A CN A2007101653221A CN 200710165322 A CN200710165322 A CN 200710165322A CN 101164608 A CN101164608 A CN 101164608A
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Abstract
The present invention provides a Chinese medicine composition for curing hypertension. Said Chinese medicine composition includes (by weight portion) 10-100 portions of eucommia bark, 50-200 portions of flowery knotweed root, 1-20 portions of veratrum root, 50-250 portions of white peony root, 30-150 portions of lyceum berry, 20-200 portions of curcuma tuber, 10-150 portions of astragalus root and 40-250 portions of fetid cassia seed. Besides, said invention also provides its preparation method.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of hypertensive Chinese medicine composition and preparation method thereof that is used for the treatment of, belong to field of Chinese medicines field.
Background technology
Hypertension is one of common disease in the world today, and not only the health of direct serious harm numerous people is again the important risk factor that causes apoplexy, coronary heart disease and renal failure.Modern medicine thinks that primary disease is based on the arteriotony rising.World Health Organization (WHO)/international hypertension alliance definite Evaluation of Diagnostic Criteria of Hypertension in 1999 is: systolic pressure 〉=140mmHg, diastolic pressure 〉=90mmHg.Clinical manifestation is dizziness, feeling of fullness in the head, headache, tinnitus etc.
Aspect hypertensive treatment, the common chemical medicament mainly contains following a few class: diuretic, receptor blocking agent, calcium antagonist, angiotensin-convertion enzyme inhibitor, angiotensin ii receptor antagonist.More than the conventional antihypertensive drugs of six big classes to the hypertension acute attack, hypertensive crisis and perioperative hypertension etc. have certain therapeutic effect, in the therapeutic process of hypertension, though chemistry medicine effect is rapidly, in the blood pressure lowering process fluctuation of blood pressure big, side effect is also big, can obviously influence the metabolism of water, electrolyte, blood fat, blood glucose etc., organs such as the coup injury heart, brain, kidney, simultaneously, these medicines are to the no improvement effects such as damage of hyperlipidemia, high blood viscosity, sclerosis of blood vessels, rake organ.So Western medicine can only be to have obeyed to fall, and has fallen clothes, again and again, takes medicine throughout one's life.
The title that does not have hypertension in motherland's traditional medicine document, but truly have the record of similar conditions, and it is belonged to " dizzy " disease categories such as " headaches " according to the clinical manifestation of primary disease.Chinese medicine especially has curative effect preferably for the clinical symptoms of improving the patient for the treatment of primary disease.
The traditional Chinese medical science thinks, primary disease be because due to the imbalance between YIN and YANG.Briefly, can be divided into two syndrome types of deficiency syndrome excess syndrome.That the patient shows as is dizzy, distending pain in the head, tinnitus, flushed face, being irritable and getting angry easily, insomnia and dreamful sleep, vexed bitter taste, yellow urine, be hard and dry, red tongue, yellow fur, wiry and frequent pulse or stringy and rolling pulse person be excess syndrome.The traditional Chinese medical science is called liver-fire and rises or excessive rising of liver-YANG.Along with advancing of disease, because the high Sheng of liver-yang with the passing of time, injure the cloudy blood of Liver and kidney, the patient can show as dizzy, tired postemphasis, dry mouth and tougue, blurred vision, soreness of the waist and knees or numb limbs and tense tendons, red tongue, tongue fur BOHUANG few body fluid, stringy and thready pulse or count accurately etc., is apoplexy due to deficiency and holds excess syndrome under the arm.The traditional Chinese medical science is called the hepatic and renal YIN deficiency, excessive rising of liver-YANG.Later stage deficiency of YIN affecting YANG to disease, that the patient can show as is dizzy, lethargy, soreness of the waist and knees or seminal emission lingering diarrhea, odontoseisis, coldness of the body with chills, nocturia frequency, thick turbid, the deep and weak pulse of the white or root of the tongue portion of loose stool, pale and tender tongue, tongue fur etc. is deficiency syndrome, and the traditional Chinese medical science is called deficiency of both YIN and YANG.The basic principle of Chinese traditional treatment primary disease is a reinforce insufficiency and reduce excessiveness, regulating yin and yang.
Summary of the invention
The object of the present invention is to provide and a kind ofly select natural Chinese medicine grass material for use, can treat hypertensive Chinese medicine composition, this Chinese medicine composition has the effect of heat clearing away suppressing the hyperactive liver, removing heat from blood blood pressure lowering, blood fat reducing.
Another object of the present invention is to provide a kind of preparation method that is used for the treatment of hypertensive Chinese medicine composition.
In order to realize the object of the invention, of the present inventionly be used for the treatment of hypertensive Chinese medicine composition, the component that comprises following weight portion: Cortex Eucommiae 10-100 part, Radix Polygoni Multiflori 50-200 part, Rhizoma et radix veratri (Radix Rhizoma Veratri) 1-20 part, Radix Paeoniae Alba 50-250 part, Fructus Lycii 30-150 part, Radix Curcumae 20-200 part, Radix Astragali 10-150 part, Semen Cassiae 40-250 part.
Of the present invention part is weight portion, such as this area kilogram commonly used, jin, two, gram etc.
Wherein, preferably: Cortex Eucommiae 30-100 part, Radix Polygoni Multiflori 80-200 part, Rhizoma et radix veratri (Radix Rhizoma Veratri) 1-10 part, Radix Paeoniae Alba 100-250 part, Fructus Lycii 50-150 part, Radix Curcumae 80-200 part, Radix Astragali 50-150 part, Semen Cassiae 100-250 part.
Be more preferably: Cortex Eucommiae 50-80 part, Radix Polygoni Multiflori 100-180 part, Rhizoma et radix veratri (Radix Rhizoma Veratri) 5-10 part, Radix Paeoniae Alba 150-200 part, Fructus Lycii 100-150 part, Radix Curcumae 150-200 part, Radix Astragali 80-120 part, Semen Cassiae 150-200 part.
Chinese medicine composition of the present invention also comprises 10-150 part Folium Mori and 10-150 part Radix Glycyrrhizae, and preferably: 40-150 part Folium Mori and 50-150 part Radix Glycyrrhizae are more preferably: 80-120 part Folium Mori and 100-150 part Radix Glycyrrhizae.
The Cortex Eucommiae has effects such as invigorating the liver and kidney, bone and muscle strengthening, blood pressure lowering, can be used for phagocytic function, calmness, the diuresis of blood pressure lowering, enhancing mononuclear phagocyte.
Radix Polygoni Multiflori has the liver benefiting of nourishing blood, the effect of beneficial essence, blood fat reducing, black beard and hair, anti-alopecia of reinforcing the kidney, and has the effect of tangible reduction serum cholesterol, and has certain adjusting immunization.
Rhizoma et radix veratri (Radix Rhizoma Veratri) contains veratrum alkaloid, the effect that has blood pressure lowering and slow down heart rate.
The Radix Astragali is warm in nature, and sweet in the mouth is returned spleen, lung meridian, the tool invigorating QI to consolidate the body surface resistance, and the diuresis toxin expelling, the effect of evacuation of pus granulation promoting has the reinforcement contraction to heart, and the strong blood vessel function of expansion is arranged, and improves cutaneous circulation and nutriture, and can bring high blood pressure down.
The contained paeoniflorin of the Radix Paeoniae Alba agree have effects such as better spasmolysis and analgesia, analgesia, convulsion, blood pressure lowering.
Radix Curcumae goes into liver, spleen two warps.Mainly can regulating QI to relieve pain, easy liver of blood circulation promoting, and can the promoting the function of the gallbladder to alleviate jaundice promoting blood circulation and stopping pain, the effect of blood fat-reducing blood pressure-decreasing.
Fructus Lycii: property is sweet, flat, return the Liver and kidney warp, has nourishing the liver and kidney, the effect of nourishing the liver to improve visual acuity, contain carotene, betanin, vitamin A, vitamin B1, vitamin B2, vitamin C and calcium, phosphorus, ferrum etc., have the leukocyte increasing activity, promote hepatocyte new life's pharmacological action, but also blood pressure lowering, blood sugar lowering, blood fat.
Semen Cassiae is the mature seed of leguminous herbaceous plant's Semen Cassiae or little Semen Cassiae, and bitter in the mouth, sweet and property are frightened, have the effect of liver heat removing and eyesight improving, loosening bowel to relieve constipation.Modern pharmacological research confirms, the contained effective ingredient of Semen Cassiae has effects such as regulating immune, antibacterial, anticancer, blood pressure lowering, blood lipid regulation and eyesight-improving bowels-relaxing.
Nutritional labeling is abundant especially in the Folium Mori, contains 18 seed amino acids of needed by human body, contains transmitter substance and depressor substance gamma aminobutyric acid, has the effect of blood pressure lowering, blood sugar lowering, blood fat reducing.
Radix Glycyrrhizae has invigorating the spleen and replenishing QI, nourishing the lung to arrest cough, relieving spasm to stop pain, the mitigation property of medicine: can be used for alleviating the toxicity of some drugs and strong, and in order to coordinate the synergy between medicine.
Chinese medicine composition of the present invention can be made various dosage forms with pharmaceutically acceptable carrier, such as tablet, capsule, pill, granule or oral liquid etc.Can adopt preparation technique means well known in the art to finish the preparation of the present composition.
Described pharmaceutically acceptable carrier is well known, for being used to prepare the usual excipients or the adjuvant of above-mentioned preparation.Excipient or adjuvant commonly used include but not limited to filler, lubricant, dispersant, wetting agent, binding agent, antioxidant or the like, such as, syrup, arabic gum, sorbitol, lactose, dextrin, starch, calcium carbonate, Pulvis Talci, Polyethylene Glycol, carboxymethyl starch sodium, magnesium stearate or the like.
The preparation method that is used for the treatment of hypertensive Chinese medicine composition of the present invention, comprise the steps: each component is mixed in proportion, the water that adds 8-12 times of medical material weight, decoct 2-3 time, each 2-3 hour, filter, merging filtrate, it is 1.25-1.4 (50 ℃) thick paste that filtrate is concentrated into relative density, adds pharmaceutically acceptable carrier again, makes various dosage forms.
Chinese medicinal composition of the present invention is all selected natural Chinese medicinal herb for use, plays synergism between each component, has the effect of blood pressure lowering, blood fat reducing, and is evident in efficacy aspect the complication that causes in treatment hypertension and hypertension.
Described hypertension is selected from the anti-Sheng type of liver-fire hypertension, type of deficiency of YIN leading to hyper activity of YANG hypertension, deficiency of both YIN and YANG type hypertension, 1 phase hypertension, 2 phase hypertension or 3 phase hypertension.
The specific embodiment
Following examples are used to illustrate the present invention, but are not used for limiting the scope of the invention.
Embodiment 1
Take by weighing the following raw materials in weight medicine: 100 kilograms of the Cortexs Eucommiae, 80 kilograms of Radix Polygoni Multiflori, 5 kilograms of Rhizoma et radix veratri (Radix Rhizoma Veratri)s, 50 kilograms of the Radix Paeoniae Albas, 30 kilograms of Fructus Lyciis, 200 kilograms of Radix Curcumaes, 50 kilograms of the Radixs Astragali, 150 kilograms of Semen Cassiaes.
With the chopping of above-mentioned raw materials medicine, add in the multi-function extractor, and add the water of 10 times of crude drug weight, heating decocted 3 hours, filter, collect filtrate, and then add the water of 8 times of amounts, decocted 2.5 hours, filter, merge filtrate twice, it is 1.25 (50 ℃) thick paste that filtrate is concentrated into relative density, drying, pulverize, with 16 mesh sieve granulate, an amount of with sucrose, mixing is a binding agent with 70% ethanol, granulates, drying, sterilization gets granule.
Embodiment 2
Take by weighing the following raw materials in weight medicine: 30 kilograms of the Cortexs Eucommiae, 180 kilograms of Radix Polygoni Multiflori, 1 kilogram of Rhizoma et radix veratri (Radix Rhizoma Veratri), 250 kilograms of the Radix Paeoniae Albas, 150 kilograms of Fructus Lyciis, 20 kilograms of Radix Curcumaes, 80 kilograms of the Radixs Astragali, 400 kilograms of Semen Cassiaes, 40 kilograms on Folium Mori, 10 kilograms in Radix Glycyrrhizae.
With the chopping of above-mentioned raw materials medicine, add in the multi-function extractor, and add the water of 12 times of crude drug weight, heating decocted 3 hours, filter, collect filtrate, and then add the water of 10 times of amounts, decocted 2.5 hours, filter, collect filtrate, add the water of 8 times of amounts again, decocted 2 hours, filter, merge three times filtrate, it is 1.40 (50 ℃) thick paste that filtrate is concentrated into relative density, drying, pulverize, with 16 mesh sieve granulate, it is an amount of to add starch, mixing, granulate, sterilization is made tablet with the tablet machine tabletting.
Embodiment 3
Take by weighing the following raw materials in weight medicine: 80 kilograms of the Cortexs Eucommiae, 50 kilograms of Radix Polygoni Multiflori, 10 kilograms of Rhizoma et radix veratri (Radix Rhizoma Veratri)s, 200 kilograms of the Radix Paeoniae Albas, 50 kilograms of Fructus Lyciis, 150 kilograms of Radix Curcumaes, 10 kilograms of the Radixs Astragali, 100 kilograms of Semen Cassiaes.
With the chopping of above-mentioned raw materials medicine, add in the multi-function extractor, and add the water of 12 times of crude drug weight, heating decocted 2.5 hours, filter, collect filtrate, and then add the water of 8 times of amounts, decocted 2 hours, filter, merge filtrate twice, it is 1.30 (50 ℃) thick paste that filtrate is concentrated into relative density, drying, pulverize, an amount of with 16 mesh sieve granulate with sucrose, mixing, with 70% ethanol is binding agent, granulates drying, pack in the capsulae vacuus, sterilization gets capsule.
Embodiment 4
Take by weighing the following raw materials in weight medicine: 50 kilograms of the Cortexs Eucommiae, 100 kilograms of Radix Polygoni Multiflori, 8 kilograms of Rhizoma et radix veratri (Radix Rhizoma Veratri)s, 100 kilograms of the Radix Paeoniae Albas, 100 kilograms of Fructus Lyciis, 800 kilograms of Radix Curcumaes, 150 kilograms of the Radixs Astragali, 200 kilograms of Semen Cassiaes, 50 kilograms in 80 kilograms on Folium Mori and Radix Glycyrrhizae.
With the chopping of above-mentioned raw materials medicine, add in the multi-function extractor, and add the water of 9 times of crude drug weight, heating decocted 3 hours, filtered, and collected filtrate, and then add the water of 10 times of amounts, and decocted 2 hours, filter, merge filtrate twice, it is 1.35 (50 ℃) thick paste that filtrate is concentrated into relative density, drying, pulverize, add Mel and mix, sterilization gets pill.
Embodiment 5
Take by weighing the following raw materials in weight medicine: 10 kilograms of the Cortexs Eucommiae, Radix Polygoni Multiflori 120 kg, 12 kilograms of Rhizoma et radix veratri (Radix Rhizoma Veratri)s, 150 kilograms of the Radix Paeoniae Albas, 60 kilograms of Fructus Lyciis, 100 kilograms of Radix Curcumaes, Radix Astragali 120 kg, 250 kilograms of Semen Cassiaes.
With the chopping of above-mentioned raw materials medicine, add in the multi-function extractor, and add the water of 10 times of crude drug weight, heating decocted 3 hours, filtered, and collected filtrate, and then add the water of 8 times of amounts, decocted 2 hours, and filtered, merge filtrate twice, it is 1.25 (50 ℃) thick paste that filtrate is concentrated into relative density, add syrup and purified water, sterilization gets oral liquid.
Embodiment 6
Basic process is with embodiment 1, and different crude drug is: 100 kilograms of the Cortexs Eucommiae, 200 kilograms of Radix Polygoni Multiflori, 20 kilograms of Rhizoma et radix veratri (Radix Rhizoma Veratri)s, Radix Paeoniae Alba 120 kg, 80 kilograms of Fructus Lyciis, 50 kilograms of Radix Curcumaes, 100 kilograms of the Radixs Astragali, 250 kilograms of Semen Cassiaes, 150 kilograms in 10 kilograms on Folium Mori and Radix Glycyrrhizae.
Embodiment 7
Basic process is with embodiment 1, and different crude drug is: 60 kilograms of the Cortexs Eucommiae, 150 kilograms of Radix Polygoni Multiflori, 2 kilograms of Rhizoma et radix veratri (Radix Rhizoma Veratri)s, 80 kilograms of the Radix Paeoniae Albas, Fructus Lycii 120 kg, 160 kilograms of Radix Curcumaes, 150 kilograms of the Radixs Astragali, 80 kilograms of Semen Cassiaes, 100 kilograms in Folium Mori 120 kg and Radix Glycyrrhizae.
Embodiment 8
Basic process is with embodiment 1, and different crude drug is: 50 kilograms of the Cortexs Eucommiae, 160 kilograms of Radix Polygoni Multiflori, 5 kilograms of Rhizoma et radix veratri (Radix Rhizoma Veratri)s, 100 kilograms of the Radix Paeoniae Albas, 50 kilograms of Fructus Lyciis, 150 kilograms of Radix Curcumaes, 80 kilograms of the Radixs Astragali, 150 kilograms of Semen Cassiaes, 50 kilograms in 150 kilograms on Folium Mori and Radix Glycyrrhizae.
Experimental example 1
The purpose of this experimental example is to study the hypotensive effect of Chinese medicine composition of the present invention.
1. experiment material
Medicine: the preparation of the embodiment of the invention 1 is mixed with the medicinal liquid of 1.12g crude drug in whole/ml with distilled water.Amounting to of the compound method of Chinese medicine composition of the present invention and dosage sees Table 1.
Amounting to of the compound method of the used Chinese medicine composition of the present invention of this experimental example of table 1 and dosage
| Animal | Drug level | The administration volume | Dosage |
| (g/ml) | (g/kg) | ||
| Rat | 1.10 | 2ml/100g | 21.3 |
| 0.25 | 2ml/100g | 5.5 |
The captopril sheet, specification: the 2.5mg/ sheet, Sino-U.S. Jin Hua pharmaceutcal corporation, Ltd produces.
Testosterone propionate injection, Shanghai the 9th pharmaceutical factory produces.
Instrument: HEM-808F electric sphygmomanometer.
Animal: SD kind rat, male, in 4 months ages of Mus, body weight 300-350 gram is provided by Xi'an Medical University's vivarium.
2. experimental technique and result
Select the SD rat, measure each Mus tail blood pressure (photoelectricity volumetric method) for three days on end earlier, ask its meansigma methods as normotensive value.Each Mus subcutaneous injection every day androlin 5mg/ then, continuous 14 days.The next day of last injection androlin, measure each rat tail pressure value, obviously be increased to 1.3kpa (or the 10mmHg that more normally raises) for forming hypertensive rat model with blood pressure.
Select 40 above-mentioned experimental hypertension rats, the height random packet of pressing pressure value, 10/group, totally 4 groups, press the listed dosage of table 1, respectively gastric infusion once, when administration 7 days and 14 days, mensuration administration each Mus pressure value after 1 hour, and being calculated as follows:
Blood pressure lowering rate={ (pressure value after the preceding pressure value-administration of administration)/(pressure value before the administration) } * 100%
Table 2 Chinese medicine composition of the present invention is to the therapeutical effect of experimental hypertension rat (meansigma methods ± SD)
| Group | Dosage | Number of animals | Systolic pressure | ||||
| (g/kg) | Only | Before the administration | After the administration 7 days | Blood pressure lowering rate (%) | After the administration 14 days | Blood pressure lowering rate (%) | |
| The normal saline group | Isometric(al) NS | 10 | 130.90± 15.73 | 136.10±25.07 | -3.97％ | 118.56± 16.66 | 9.42％ |
| Kato is general | 0.04 | 10 | 129.48± | 87.50±8.67 *** | 32.42％ | 80.90± | 37.51％ |
| Sharp group | 25.12 | 14.36 *** | |||||
| Embodiment 1 | 21.3 | 10 | 130.45± 14.56 | 104.21± 16.47 ** | 20.11％ | 95.78± 13.65 ** | 26.57％ |
| Embodiment 1 | 4.5 | 10 | 129.35± 28.05 | 99.78±17.78 ** | 22.86％ | 96.88± 14.12 * | 25.10％ |
Remarks: compare with the normal saline group after the administration
*P＜0.05,
*P＜0.01,
* *P＜0.001,
Compare with normal arterial pressure after the modeling
* *P＜0.001.
Table 3 Chinese medicine composition of the present invention is to the therapeutical effect of experimental hypertension rat (meansigma methods ± SD)
| Group | Dosage | Number of animals | Diastolic pressure | ||||
| (g/kg) | Only | Before the administration | After the administration 7 days | Blood pressure lowering rate (%) | After the administration 14 days | Blood pressure lowering rate (%) | |
| The normal saline group | Isometric(al) NS | 10 | 63.96± 13.73 | 91.56± 25.07 | -43.15％ | 69.12± 15.78 | -8.06％ |
| Captopril group | 0.04 | 10 | 62.55± 12.34 | 49.07± 9.45 *** | 20.88％ | 45.90± 11.36 *** | 26.61％ |
| Embodiment 1 | 21.3 | 10 | 68.90± 14.56 | 65.23± 15.34 ** | 5.33％ | 51.13± 12.65 ** | 25.78％ |
| Embodiment 1 | 4.5 | 10 | 65.11± 17.88 | 56.74± 18.78 ** | 12.85％ | 55.87± 13.82 * | 14.19％ |
Remarks: compare with the normal saline group after the administration
*P＜0.05,
*P＜0.01,
* *P＜0.001,
Compare with normal arterial pressure after the modeling
* *P＜0.001.
By table 2 and table 3 result as seen, 21.3 and 5.5g/kg Chinese medicine composition of the present invention the experimental hypertension rat that hormone brings out is had the obvious treatment effect.After administration 7 days and 14 days, 21.3 dosage groups can significantly reduce systolic pressure (p＜0.01), respectively can be obviously and significantly reduce diastolic pressure (p＜0.05 and p＜0.01).After administration 7 days and 14 days, small dose group respectively can be significantly and is obviously reduced systolic pressure (p＜0.05 and p＜0.01), can significantly reduce diastolic pressure (p＜0.01) 7 days the time after the administration.
Claims (8)
1. one kind is used for the treatment of hypertensive Chinese medicine composition, it is characterized in that, comprises the component of following weight portion: Cortex Eucommiae 10-100 part, Radix Polygoni Multiflori 50-200 part, Rhizoma et radix veratri (Radix Rhizoma Veratri) 1-20 part, Radix Paeoniae Alba 50-250 part, Fructus Lycii 30-150 part, Radix Curcumae 20-200 part, Radix Astragali 10-150 part, Semen Cassiae 40-250 part.
2. according to claim 1ly be used for the treatment of hypertensive Chinese medicine composition, it is characterized in that, the component that comprises following weight portion: Cortex Eucommiae 30-100 part, Radix Polygoni Multiflori 80-200 part, Rhizoma et radix veratri (Radix Rhizoma Veratri) 2-10 part, Radix Paeoniae Alba 100-250 part, Fructus Lycii 50-150 part, Radix Curcumae 80-200 part, Radix Astragali 50-150 part, Semen Cassiae 100-250 part.
3. according to claim 1 and 2ly be used for the treatment of hypertensive Chinese medicine composition, it is characterized in that, the component that comprises following weight portion: Cortex Eucommiae 50-80 part, Radix Polygoni Multiflori 100-180 part, Rhizoma et radix veratri (Radix Rhizoma Veratri) 5-10 part, Radix Paeoniae Alba 150-200 part, Fructus Lycii 100-150 part, Radix Curcumae 150-200 part, Radix Astragali 80-120 part, Semen Cassiae 150-200 part.
4. describedly be used for the treatment of hypertensive Chinese medicine composition according to any one of claim 1-3, it is characterized in that, also comprise 10-150 part Folium Mori and 10-150 part Radix Glycyrrhizae.
5. according to claim 4ly be used for the treatment of hypertensive Chinese medicine composition, it is characterized in that, comprise 40-150 part Folium Mori and 50-150 part Radix Glycyrrhizae.
6. describedly be used for the treatment of hypertensive Chinese medicine composition according to claim 4 or 5, it is characterized in that, comprise 80-120 part Folium Mori and 100-150 part Radix Glycyrrhizae.
7. describedly be used for the treatment of hypertensive Chinese medicine composition according to any one of claim 1-6, it is characterized in that described Chinese medicine composition and pharmaceutically acceptable carrier are made tablet, capsule, pill, granule or oral liquid.
8. one kind prepares any one of claim 1-7 and describedly is used for the treatment of hypertensive Chinese medicine composition, it is characterized in that, comprise the steps: each component is mixed in proportion, add the water of 8-12 times of medical material weight, decoct 2-3 time, each 2-3 hour, filter, merging filtrate, it is 1.25-1.4 (50 ℃) thick paste that filtrate is concentrated into relative density, add pharmaceutically acceptable carrier again, make various dosage forms.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109125502A (en) * | 2018-10-22 | 2019-01-04 | 宋子刚 | Reducing blood lipid on behalf of the tea and preparation method thereof |
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2007
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109125502A (en) * | 2018-10-22 | 2019-01-04 | 宋子刚 | Reducing blood lipid on behalf of the tea and preparation method thereof |
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