CN101163414A - Food or drug comprising lactic acid bacterium containing mineral - Google Patents
Food or drug comprising lactic acid bacterium containing mineral Download PDFInfo
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- CN101163414A CN101163414A CNA200680003122XA CN200680003122A CN101163414A CN 101163414 A CN101163414 A CN 101163414A CN A200680003122X A CNA200680003122X A CN A200680003122XA CN 200680003122 A CN200680003122 A CN 200680003122A CN 101163414 A CN101163414 A CN 101163414A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Abstract
It is intended to disclose a composition to be used by dispersing/dissolving, preferably before using, in an aqueous vehicle such as water which is excellent in the dispersion/dissolution properties in the aqueous vehicle and stability after the dispersion/dissolution and the dispersion/solution of which in the aqueous vehicle is favorable in appearance, taste, flavor and texture such as coarseness as a food or a drug. The above-described composition is a composition to be used by dispersing/dissolving in an aqueous vehicle characterized by comprising a lactic acid bacterium containing a mineral component at t high concentration.
Description
Invention field
The present invention relates to comprise the lactic acid bacteria that contains the high concentration mineral composition, the composition that dispersed/dissolved is used in aqueous medium.
Background technology
Mineral matter is to regulate the necessary nutrient of human physiological functions, but can't synthesize in human body, therefore must be absorbed by the outside.If mineral deficiency for example lacks zinc degradation under dysgeusia, the immunologic function then takes place, lack copper anaemia then takes place, can observe in addition with heart related unusual.Though determined the suitable requirement of mineral matter so far, year March in April, 2005 to 2010 five in the period of in predetermined " the Japanese food intake standard " that adopt, still continue to use the intake standard that Japanese present situation has been determined each mineral matter.
Except that medicine, the complementary goods of mineral matter picked-up mainly contains: be used for the liquid food to the extra-nutritions such as old man of perioperative patient or general food dysphagia; Replenish not only when malnutrition or digestion and absorption function are low, the usual also food of not enough mineral matter easily; And with when motion or prevent obesity and supplement the nutrients when going on a diet to be the food of purpose.
Though the demand to the medicine or the food of this additional mineral composition is arranged, existing in fact at variety of issue.Particularly for facing before the picked-up,, also require dispersed and stable in water etc. except the taste of goods, local flavor, mouthfeel such as rough with the water-soluble food that absorbs of the composition of forms such as powder.And, belonging in the per os liquid food of food except adjusting milk powder for baby, the interpolation of inorganic minerals such as zinc, manganese is not given the ratification as yet.Therefore, the source of supply of mineral matter is confined to for example raw-food material etc.
Contain in the trial of yeast as raw-food material of mineral matter in use, proposed the high yeast (Japanese kokai publication hei 8-332082 communique) of zinc content.The concrete form of the not mentioned food that utilizes in this communique.In addition, the yeast that also proposes to contain mineral matter is made beauty treatment, healthy usefulness composition (Japanese kokai publication hei 9-124438 communique).In this communique unexposed face the picked-up before with the water-soluble composition that absorbs of the composition of forms such as powder.
The liquid food of the yeast that contains the high concentration mineral matter has been proposed to be added with in TOHKEMY 2001-46016 number.This communique has been put down in writing following content in 0029 section, promptly when using the yeast of high mineral content, if its use level surpasses 0.2% weight, the precipitation of yeast then takes place, the dispersion stabilization variation is easy to generate problem aspect rerum natura, also find to have rough sense in sensory evaluation.In addition, this communique has hinted that also the taste that yeast self had, local flavor lack hobby property, owing to deterioration peculiar smell, foreign odor take place easily when preserving.
WO92/21749 communique (the flat 6-508516 communique of corresponding Japanese Unexamined Patent Application Publication) discloses the preparation method of the lactic acid bacteria that contains the high concentration mineral matter, but unexposed be the concrete food and the medicine of raw material with the gained lactic acid bacteria.
Summary of the invention
The lactic acid bacteria that recent findings such as the inventor contain the high concentration mineral composition in the aqueous medium that with water is representative dispersed/dissolved and the excellent in stability after the dispersed/dissolved, and in aqueous medium the composition after the dispersed/dissolved as food or medicine, also good aspect mouthfeels such as outward appearance, taste, local flavor and rough sense, be dispersed/dissolved and can advantageously utilizing in the composition that uses in aqueous medium.The present invention just is being based on above-mentioned discovery and is finishing.
Therefore, the composition that the object of the present invention is to provide a kind of dispersed/dissolved in aqueous medium and use, said composition in aqueous medium dispersed/dissolved and the excellent in stability after the dispersed/dissolved, and in aqueous medium the composition after the dispersed/dissolved as food or medicine, also preferred compositions aspect mouthfeels such as outward appearance, taste, local flavor and rough sense.
Therefore, the present composition is characterised in that and comprises the lactic acid bacteria that contains the high concentration mineral composition, is dispersed/dissolved and the composition that uses in aqueous medium water.
Detailed Description Of The Invention
The lactic acid bacteria that contains mineral matter
The used lactic acid bacteria of the present invention contains the high concentration mineral composition.The mineral matter that comprises in the used lactic acid bacteria of the present invention for example has the mineral matter that is selected from magnesium, iron, manganese, zinc, copper, selenium, chromium and molybdenum.These mineral matters can one or more be included in the lactic acid bacteria.In the preferred embodiment of the invention, the kind and the preferred content of mineral matter are as follows.That is,
Preferred 7% weight of-magnesium or more than, more preferably 14% weight,
Preferred 4.5% weight of-iron or more than, more preferably 9.5% weight or more than,
Preferred 5% weight of-manganese or more than, more preferably 10% weight or more than,
Preferred 4.5% weight of-zinc or more than, more preferably 9.5% weight or more than,
Preferred 0.9% weight of-copper or more than, more preferably 1.8% weight or more than,
Preferred 0.05% weight of-selenium or more than, more preferably 0.1% weight or more than,
Preferred 0.1% weight of-chromium or more than, more preferably 0.2% weight or more than,
Preferred 0.1% weight of-molybdenum or more than, more preferably 0.2% weight or more than.
The used lactic acid bacteria of the present invention can obtain by comprising the medium culture of wishing the mineral matter that contains basically.By the culture medium except that mineral composition is formed suitably, can further raise the efficiency, in the present invention,, its preparation method is not particularly limited as long as contain the high concentration mineral composition and there is not safety issue in the people.
Available lactic acid bacteria can obtain by the method for for example middle record of above-mentioned WO92/21749 communique (the flat 6-508516 communique of corresponding Japanese Unexamined Patent Application Publication) among the present invention.
The lactic acid bacteria market that contains the high concentration mineral composition is on sale, and for example having can be by " Biogurt " of GrowCompany Inc. (NJ USA Nackensack) acquisition.Biogurt has Biogurt magnesium (containing 14～16% magnesium), Biogurt iron (containing 9.5～11% iron), Biogurt manganese (containing manganese 10～12%), Biogurt zinc (containing 9.5～10% zinc), Biogurt copper (containing 1.8～2.3% bronze medals) etc., all can suitably be used for the present invention.
Composition
Composition of the present invention dispersed/dissolved and using in aqueous solvent.Composition of the present invention is comprised people's animal picked-up after the dispersed/dissolved in this aqueous solvent.Composition of the present invention in aqueous medium dispersed/dissolved and the excellent in stability after the dispersed/dissolved.Particularly owing to easy dispersed/dissolved in aqueous medium, preferably as the composition use of absorbing after the time spent modulation.For food and medicine, consider that from the angle of security comparatively favourable situation is that the form with composition provides, time spent dispersed/dissolved in aqueous medium is used.In this case, if in aqueous medium required time of dispersed/dissolved elongated, then dispersed/dissolved also fully just is not ingested, expectation can not fully absorb, and perhaps may become the commodity of shortcoming attraction.For composition of the present invention, the operation of ordinary person by in containers such as cup, mixing, about 40 seconds with the interior time in dispersed/dissolved fully, for preferred embodiment, below 20 seconds in addition the time before and after 10 seconds can complete dispersed/dissolved, be very favourable therefore.
Therefore, according to the preferred embodiment of the invention, composition of the present invention before facing picked-up in aqueous solvent time spent dispersed/dissolved and using.Among the present invention, " picked-up " extensively comprise composition of the present invention in aqueous solvent, disperse/material that solvent forms enters in the body by alimentary canal, comprises not only that therefore per os is edible, also comprise and absorbing through intestines through pipeline.Therefore, composition of the present invention specifically provides as food or medicine.According to the preferred embodiments of the invention, the food of mineral matter or medicine, nutrient supplement food, low-calorie diet or the diet food of particularly having strengthened mineral composition provide as a supplement.According to another preferred embodiment of the present invention, because composition of the present invention can be used as the liquid food utilization after the dispersed/dissolved in aqueous medium, composition of the present invention provides as the edible food of modulated stream.
As long as the aqueous medium of present composition dispersed/dissolved is based on water, and can obtain the good effect of dispersed/dissolved of the present invention described later gets final product, be not particularly limited, its object lesson has the water that comprises hot water, milk, soymilk, whey beverage, cold drink water etc., preferably comprises the water of hot water.
Composition of the present invention in aqueous medium dispersed/dissolved and the excellent in stability after the dispersed/dissolved.And in aqueous medium behind the dispersion/solvent as food or medicine, have good advantage aspect mouthfeels such as outward appearance, taste, local flavor and rough sense.According to the inventor's etc. discovery,,, still show good dissolution and stability even surpass interpolation boundary 0.2% weight of the yeast of the high mineral content of being advised for above-mentioned TOHKEMY 2001-46016 number for composition of the present invention.Therefore, compare with the situation of yeast, concentration that can be higher is added mineral composition in the composition to, can increase its intake.And composition of the present invention is also favourable than the yeast of high mineral content aspect mouthfeels such as outward appearance, taste, local flavor and rough sense.Compare with the yeast that contains the high concentration mineral composition equally, the lactic acid bacteria that contains the high concentration mineral composition aspect above-mentioned favourable can be described as beat all.
Composition of the present invention time spent in aqueous medium can dissolution gets final product, and its form is Powdered, graininess or the concentrated liquid shape that contains the high concentration lactic acid bacteria, semi-solid etc., is not particularly limited.According to the preferred embodiment of the invention, composition of the present invention according to circumstances with other composition granulations of aftermentioned, become powder.Prilling process is not particularly limited, and preferably utilizes spray-drying, stirring-granulating method, fluidized bed prilling method, rotating granulation method, extruding pelletization method etc.Also can after granulation, mix other compositions of aftermentioned, as composition of the present invention.From the present composition aqueous medium dispersed/dissolved and the excellent in stability after the dispersed/dissolved, mouthfeel aspects such as outward appearance, taste, local flavor and rough sense as food or medicine consider that preferably being made into bulk specific weight is 0.22～0.45g/cm
3Composition.
The content of lactic acid bacteria can suitably decision after the concentration of the mineral composition of consider wishing to comprise in the present composition, with the lactic acid bacteria of dried forms convert preferably contain 0.001% weight or more than, more preferably 0.01～10% weight.According to the preferred embodiments of the invention, the content of lactic acid bacteria converts as follows with the lactic acid bacteria of dried forms:
When-lactic acid bacteria contains magnesium, preferred 0.4～8% weight,
During-lactic acid bacteria iron content, preferred 0.02～0.5% weight,
When-lactic acid bacteria contains manganese, preferred 0.007～0.2% weight,
When-lactic acid bacteria contains zinc, preferred 0.01～0.3% weight,
During-lactic acid bacteria cupric, preferred 0.007～0.2% weight,
When-lactic acid bacteria contains selenium, preferred 0.005～0.1% weight,
When-lactic acid bacteria contains chromium, preferred 0.003～0.06% weight,
When-lactic acid bacteria contains molybdenum, preferred 0.002～0.04% weight.
Except that above-mentioned lactic acid bacteria, composition of the present invention can contain other compositions as medicine or food needs.For example can contain protein, lipid, carbohydrate, food fiber and vitamin etc.Protein has for example lactoprotein (full milk albumen, casein-sodium, calcium caseinate etc.) and hydrolysate, other animal protein (egg protein, gelatin etc.) and hydrolysate and vegetable protein (soybean etc.) and hydrolysate thereof.According to the preferred embodiment of the invention, composition of the present invention can contain protein as main component.Total protein content can suitably determine, if purpose is 1/3 of picked-up essential intake every day, about then preferred 13～30g/400ml.Vitamin also can add vitamin A, B
1, B
2, B
6, B
12, C, D, E, K
2, nicotinic acid, pantothenic acid, folic acid etc., can add separately also and can mix.Composition of the present invention can also contain dry yeast (for example brewer's yeast, Saccharomyces cerevisiae etc.).
In the present invention, mineral composition provides with the form that is included in the lactic acid bacteria, replenishes or auxiliary element as it, and form that also can the acceptable salt of food contains sodium, calcium, magnesium, potassium, iron.
According to the preferred embodiments of the invention, the total amount of heat of the present composition also can suitably determine, during the composition that supplements the nutrients during for example as fat-reducing, making its total amount of heat usually is about 0.4 kilocalorie/ml, about preferred 0.3～0.5 kilocalorie/ml.When each consumption is an individual packages, preferably make its total amount of heat be 300 kilocalories or below.According to other embodiments, under the situation of hope, the total amount of heat of each consumption can be set at 150,160,170,180,190,200,210,220,230,240,250,260,270,280,290,300,310,320,330,340 or 350 kilocalories.
Composition of the present invention also can contain the yeast of high concentration mineral composition in the scope that does not influence hobby property or dispersiveness, stability.
That other embodiments of the present invention provide is liquid, the preparation method of semi-solid or gel-form composition, it is characterized in that comprising at least the composition dispersed/dissolved in aqueous medium with the invention described above.As mentioned above, composition of the present invention in aqueous medium dispersed/dissolved and the excellent in stability after the dispersed/dissolved.Therefore, preparation in accordance with the present invention can effectively prepare liquid, the semi-solid or the gel-form composition of excellent in stability.In addition, as mentioned above, composition of the present invention in aqueous medium after the dispersed/dissolved as food or medicine, have good advantage aspect mouthfeels such as outward appearance, taste, local flavor and rough sense.Therefore, liquid, semi-solid that is obtained by preparation method of the present invention or gel-form composition are specifically as food or medicine, be preferably used as the food or the medicine that replenish mineral matter, further as nutrient supplement food, low-calorie diet, diet food, the liquid food of strengthening mineral composition.
Embodiment
Illustrate in greater detail the present invention by following examples, but the present invention is not limited to these embodiment.Below unless otherwise noted, percentage is benchmark with weight.
The modulation of [embodiment 1] composition
(1) lactic acid bacteria
Lactic acid bacteria of using in following examples and the comparative example and yeast and their content of mineral substances are as follows.
Table 1
Above-mentioned high mineral content lactic acid bacteria Biogurt is available from Grow Company Inc. (N.J. Nackensack), and high mineral content yeast is available from Kelatron Co. (Utah, USA Ogden).
(2) modulation of composition
Prepare the composition of record in above-mentioned lactic acid bacteria or yeast and the following table 2.The composition of record in the table is mixed, with respect to the 1Kg mixture with 230ml water as adhesive, the fluidized bed pelletizer that utilizes the preparation of Off ロ ィ ン ト Productivity industry society granulation 30 minutes respectively.At this moment, the intake air temperature of fluidized bed pelletizer is 75 ℃, and delivery temperature is 40 ℃.
To pass through 20 mesh sieves through the composition of granulation, bulk specific weight and moisture value will be adjusted to 0.30 ± 0.05g/cm respectively
3With 3 ± 1%.Resulting composition is as embodiment 1 and comparative example 1.
In the composition that table 2 is put down in writing, the composition of minerals and vitamins is as shown in table 3, mixes by identical amount.In addition, the biomass with brewer's yeast adjustment lactic acid bacteria or yeast makes it reach equal quantities.
Table 2
(other blending constituents)
| Lactoprotein | 25.000 | 25.000 |
| Soybean protein | 20.000 | 20.000 |
| Water-soluble food fiber | 15.100 | 15.100 |
| Brewer's yeast | 2.685 | 0.020 |
| Glucomannans | 2.000 | 2.000 |
| Coral calcium | 1.400 | 1.400 |
| Potassium gluconate | 6.490 | 6.490 |
| Vitamin mixtures | 0.240 | 0.240 |
| Glucose | 9.000 | 9.000 |
| Skimmed milk power | 8.000 | 8.000 |
| The fruit juice powder | 0.300 | 0.300 |
| Sweetener | 0.100 | 0.100 |
| Colouring agent | 7.000 | 7.000 |
| Spices | 1.100 | 1.100 |
| Add up to | 100.00 | 100.00 |
Table 3
Further the modulation composition is identical with comparative example 1 with the foregoing description 1, but change granulation condition etc. and composition that bulk specific weight is changed, with it as embodiment 2～5 and comparative example 2～5.
[embodiment 1] dispersiveness in water
The composition of 50g embodiment 1～5 and comparative example 1～5 is mixed with the normal-temperature water of 350ml, stir under certain condition,, observe its form until even dispersion with magnetic stirring apparatus.To the composition of each embodiment and comparative example, carry out 3 groups of aforesaid operations respectively.
The results are shown in the following table.
Table 4
| Embodiment 1 | Comparative example 1 | |
| In water, evenly disperse the required time | 1. 10 seconds 2. 14 seconds 3. 12 seconds average 12 seconds | 1. 55 seconds 2. 63 seconds 3. 53 seconds average 57 seconds |
| Outward appearance when in water, disperseing | Form little flocculate, but by stirring than being easier to even dispersion | The group of formation reaches homogeneously dispersed state and confirms to have big flocculate before easily |
Table 5
[embodiment 2] dispersion stabilization
The stability of following evaluation embodiment 1～5 and comparative example 1.Dispersion is transferred to respectively in the graduated cylinder of 100ml, left standstill 120 minutes, observe the state variation of dispersion during this period.
The result is as shown in table 6 below.
Table 6
| Time of repose (minute) | Embodiment 1～5 | Comparative example 1 |
| 0 | -(evenly disperseing) | -(evenly disperseing) |
| 5 | No change | No change |
| 10 | No change | Confirm the flocculate of slightly aggegation |
| 15 | No change | Confirm to have the flocculate of aggegation |
| 30 | No change | Separation/precipitation that agglutinator is arranged |
| 60 | The bottom is the flocculate of aggegation slightly | Tangible agglutinator precipitation is arranged |
| 90 | The bottom is the separation of agglutinator slightly | Tangible agglutinator precipitation is arranged |
| 120 | The bottom is slightly separated/is precipitated | Tangible agglutinator precipitation is arranged |
[embodiment 3] sensory evaluation test
By 12 skilled judges the dispersion of embodiment 1 and comparative example 1 gained is carried out sensory evaluation.That is, outward appearance, taste/local flavor, the mouthfeel (rough sense) of adjusted dispersion are estimated.
Table 7
| Item compared | Embodiment 1 | Comparative example 1 |
| Outward appearance | With respect to comparative example, there is not precipitation, very white, seem very delicious | With respect to embodiment, brown is strong, and some precipitations are arranged, and seems not to be very good eating |
| Taste/local flavor | Delicious | Bitter taste from yeast is arranged, be not very good eating |
| Rough sense | Almost do not have | In mouth, feel rough |
For embodiment 2～5 and comparative example 2～5, carry out following experiment by 12 judge's commute dissolubilities (easily disperse).That is, the 50g composition is mixed with the 350ml normal-temperature water, utilize each personal hand of spatula to stir and make its dispersion.As a result, the number of dissolving is easily answered in following evaluation.
Estimate *: answer 0～2 of easy dissolving person
Estimate △: answer 3～5 of easy dissolving persons
Estimate zero: answer 6～8 of easy dissolving persons
Estimate ◎: answer 9～12 of easy dissolving persons
The following souvenir of result carries.
Table 8
| Embodiment | Estimate | Comparative example | Estimate |
| 2 | ◎ | 2 | △ |
| 3 | ◎ | 3 | △ |
| 4 | ◎ | 4 | × |
| 5 | ○ | 5 | × |
Claims (25)
1. dispersed/dissolved and the composition that uses is characterized in that comprising the lactic acid bacteria that contains the high concentration mineral composition in aqueous medium.
2. the composition of claim 1, wherein said lactic acid bacteria contains at least a mineral matter that is selected from magnesium, iron, manganese, zinc, copper, selenium, chromium and molybdenum with high concentration.
3. claim 1 or 2 composition, wherein said lactic acid bacteria contains 7% weight or above magnesium, 4.5% weight or above iron, 5% weight or above manganese, 4.5% weight or above zinc, 0.9% weight or above copper, 0.05% weight or above selenium, 0.1% weight or above chromium or 0.1% weight or above molybdenum.
4. each composition in the claim 1～3, wherein said lactic acid bacteria with the lactic acid bacteria conversion content of dried forms be 0.001% weight or more than.
5. each composition in the claim 1～4, wherein
When described lactic acid bacteria contains magnesium, convert with the lactic acid bacteria of dried forms, the content of this lactic acid bacteria is 0.4～8% weight,
During described lactic acid bacteria iron content, convert with the lactic acid bacteria of dried forms, the content of this lactic acid bacteria is 0.02～0.5% weight,
When described lactic acid bacteria contains manganese, convert with the lactic acid bacteria of dried forms, the content of this lactic acid bacteria is 0.007～0.2% weight,
When described lactic acid bacteria contains zinc, convert with the lactic acid bacteria of dried forms, the content of this lactic acid bacteria is 0.01～0.3% weight,
During described lactic acid bacteria cupric, convert with the lactic acid bacteria of dried forms, the content of this lactic acid bacteria is 0.007～0.2% weight,
When described lactic acid bacteria contains selenium, convert with the lactic acid bacteria of dried forms, the content of this lactic acid bacteria is 0.005～0.1% weight,
When described lactic acid bacteria contains chromium, convert with the lactic acid bacteria of dried forms, the content of this lactic acid bacteria is 0.003～0.06% weight,
When described lactic acid bacteria contains molybdenum, convert with the lactic acid bacteria of dried forms, the content of this lactic acid bacteria is 0.002～0.04% weight.
6. each composition in the claim 1～5, it is the form of Powdered, graininess, liquid or semi-solid.
7. each composition in the claim 1～6, its time spent dispersed/dissolved in aqueous medium is used.
8. each composition in the claim 1～7, it contains protein.
9. each composition in the claim 1～8, it also contains lipid, carbohydrate, food fiber, vitamin or dry yeast.
10. each composition in the claim 1～9, its bulk specific weight is 0.22～0.45g/cm
3
When 11. each composition in the claim 1～10, its ampoule are an independent packaging, total amount of heat be 300 kilocalories or below.
12. each preparation of compositions method in the claim 1～11 is characterized in that and will contain the lactic acid bacteria granulation of high concentration mineral composition.
13. the preparation method of claim 12, wherein said granulation step add protein, lipid, carbohydrate, food fiber, vitamin or dry yeast and carry out.
14. the preparation method of claim 12 wherein further comprises mixed protein, lipid, carbohydrate, food fiber, vitamin or dry yeast after granulation.
15. each preparation method in the claim 11～14, wherein carrying out granulation, to make the bulk specific weight of resulting composition be 0.22～0.45g/cm
3
16. comprise the food of each composition in the claim 1～11.
17. the food of claim 16, it is the edible food of mineral matter supplement, low-calorie diet, diet food or modulated stream.
18. comprise the medicine of each composition in the claim 1～11.
19. the preparation method of liquid, semi-solid or gel-form composition is characterized in that comprising at least with each composition dispersed/dissolved in aqueous medium in the claim 1～11.
20. the preparation method of claim 19, the time spent is with described composition dispersed/dissolved in aqueous medium.
21. liquid, semi-solid or gel-form composition by the preparation of the method for claim 19 or 20.
22. comprise the food of the composition of claim 21.
23. the food of claim 22, it is mineral matter supplement, low-calorie diet, diet food or liquid food.
24. comprise the medicine of the composition of claim 21.
25. the composition that comprises the lactic acid bacteria that contains the high concentration mineral composition is in liquid, the semi-solid of preparation time spent dispersed/dissolved in aqueous medium or the application in the gel-form composition.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005023874 | 2005-01-31 | ||
| JP023874/2005 | 2005-01-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101163414A true CN101163414A (en) | 2008-04-16 |
Family
ID=36740538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA200680003122XA Pending CN101163414A (en) | 2005-01-31 | 2006-01-31 | Food or drug comprising lactic acid bacterium containing mineral |
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| Country | Link |
|---|---|
| KR (1) | KR20080009680A (en) |
| CN (1) | CN101163414A (en) |
| WO (1) | WO2006080522A1 (en) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020036229A1 (en) * | 2018-08-17 | 2020-02-20 | イチビキ株式会社 | Lactic acid bacterium, agent for increasing blood iron, and agent for ameliorating anemia |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54157890A (en) * | 1978-05-29 | 1979-12-13 | Sapporo Breweries | Production of microorganism cells |
| JPS62220157A (en) * | 1986-03-20 | 1987-09-28 | Masato Akutsu | Production of germanium-containing food |
| SE463796B (en) * | 1988-03-09 | 1991-01-28 | Carl Erik Albertsson | PROCEDURES FOR PREPARING A NUTRITIONAL COMPOSITION AND THEREFORE PREPARED NUTRITIONAL COMPOSITION |
| US6479050B1 (en) * | 1991-06-03 | 2002-11-12 | Innovi N.V. | Trace element-rich additive, method for preparing same, preparation in which the additive is included and use thereof |
| JP3017493B1 (en) * | 1999-02-25 | 2000-03-06 | 明治乳業株式会社 | Autoimmune disease prevention composition |
| JP3046303B1 (en) * | 1999-06-24 | 2000-05-29 | 明治乳業株式会社 | Helicobacter pylori eradication food and drink |
| JP4308481B2 (en) * | 2002-06-18 | 2009-08-05 | 独立行政法人農業・食品産業技術総合研究機構 | Antiallergic agent |
-
2006
- 2006-01-31 KR KR1020077019820A patent/KR20080009680A/en not_active Application Discontinuation
- 2006-01-31 WO PCT/JP2006/301539 patent/WO2006080522A1/en not_active Application Discontinuation
- 2006-01-31 CN CNA200680003122XA patent/CN101163414A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20080009680A (en) | 2008-01-29 |
| WO2006080522A1 (en) | 2006-08-03 |
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Open date: 20080416 |