CN101152529B - 一种治疗脱发的外用复方中药涂抹剂及其制备方法 - Google Patents
一种治疗脱发的外用复方中药涂抹剂及其制备方法 Download PDFInfo
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- CN101152529B CN101152529B CN2007101574978A CN200710157497A CN101152529B CN 101152529 B CN101152529 B CN 101152529B CN 2007101574978 A CN2007101574978 A CN 2007101574978A CN 200710157497 A CN200710157497 A CN 200710157497A CN 101152529 B CN101152529 B CN 101152529B
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Abstract
一种治疗脱发的外用复方中药涂抹剂及其制备方法，采用天然植物：人参、黄芪、枸杞、何首乌、补骨酯、侧柏叶、干姜等，配以枣树枝、皂角等；制备方法：按一定比例混合后粉碎，过200目筛，经乙醇浸泡、加温萃取制成外用复方中药涂抹剂以及喷剂、洗液。本发明药物具有活血化淤，补气补血，刺激毛襄再生，达到防止脱发及生发之功效，可用于治疗神经性脱发、脂溢性脱发、中老年脱发、毛发稀疏、脱眉等病症，具有控制脱发，促进毛发生长的作用，疗效好，见效快，无毒副作用，使用安全。
Description
一种治疗脱发的外用复方中药涂抹剂及其制备方法
技术领域
[0001] 本发明涉及治疗脱发、促进毛囊再生的中药制剂及制备方法。 背景技术
[0002] 随着社会的快速发展，人们的工作和生活节奏也越来越快，由于工作压力、精神刺 激、睡眠不良、遗传因素等各种原因，使脱发的发生率较高，并且趋于低龄化。脱发给患者带 来诸多烦恼，给很多人造成了极大的精神痛苦，甚至部分患者产生自卑感等心理障碍。保持 满头乌黑茂密的头发，是人们的共同心愿，所以美容美发自然成为人们提高生活质量的重 要组成部分。近年来临床应用的几种主要治疗脱发、生发药，效果均不够理想。如口服中药 养血生发胶囊及销售中的防脱发搽剂，均存在疗效长，生发慢，价格昂贵等缺点。
发明内容
[0003] 本发明的目的是提供一种治疗脱发的外用复方中药涂抹剂及其制备方法，治疗多 种原因所至毛发稀疏、脱发、脱眉等症。
[0004] 一种治疗脱发的外用复方中药涂抹剂，以天然植物为原料，其特征在于药物组份 按重量比为：（1)人参1〜3份、何首乌1〜3份、黄芪1〜3份、柏子仁1〜3份、当归1〜 3份、补骨脂1〜3份、茯苓1〜3份、桃仁1〜3份、红花1〜3份、干姜1〜3份；（2)枣 树枝4〜10份、松树枝4〜10份、桃树枝4〜10份、柳树枝4〜10份、大蒜4〜10份、侧 柏叶10〜20份、桑叶10〜20份、皂角10〜20份。制备方法：分别将原料（1)和（2)药 物粉碎、过筛，将（1)粉末状混合物放入玻璃容器，用浓度45%乙醇浸泡7天，药物与乙醇的 容积比为1 ： 2;将（2)粉末状混合物与蒸馏水按容积比1 ： 2浸泡24小时后煮沸，放入 玻璃容器中加入乙醇，使溶液的乙醇终浓度达到10%，浸泡5天；分别将（1)和⑵药物上 清液过滤后混合得药物原液，再加入原液100 ： 0.5〜1的二甲基亚砜制得涂抹剂。
[0005] 本发明药物经91例脱发者（中国64例，韩国27例）使用后，有效率达到87 %。 部分曾使用多种生发药物无效的严重秃顶完全无发者在使用本品1-3个月期间，都重新长 出了新发。本药具有活血化淤，补气补血，刺激毛襄再生，达到防止脱发及生发之功效，可用 于治疗神经性脱发、脂溢性脱发、中老年脱发、毛发稀疏、脱眉等病症。具有控制脱发，促进 毛发生长的作用。
[0006] 本发明还将涂抹剂药物原液稀释后制成喷剂和洗液。喷剂方便携带，每天可多次 使用。洗液有利于整体毛发稀疏的修复。
具体实施方式
[0007] 本发明的外用复方中药涂抹剂，以天然植物为原料，原料准备分为两部分，其特征 在于药物组份按重量比为：原料（1)人参1〜3份、何首乌1〜3份、黄芪1〜3份、柏子仁 1〜3份、当归1〜3份、补骨脂1〜3份、茯苓1〜3份、桃仁1〜3份、红花1〜3份、干 姜1〜3份；原料⑵枣树枝4〜10份、松树枝4〜10份、桃树枝4〜10份、柳树枝4〜
310份、大蒜4〜10份、侧柏叶10〜20份、桑叶10〜20份、皂角10〜20份。
[0008] 制备方法：分别将原料（1)和（2)粉碎，过筛200目。将粉末状原料（1)混合物放 入玻璃容器中，用乙醇浸泡，原料（1)与乙醇的容积比为1 ： 2，浓度45%乙醇浸泡7天，保 持室温20-25°C。将粉末状原料（2)混合物与蒸馏水按容积比1 ： 2浸泡，24小时后煮沸， 放入玻璃容器中加入乙醇，使溶液的乙醇终浓度达到10%，浸泡5天。每天用木棍分别对原 料（1)和（2)混合物搅拌一次。分别将（1)和（2)药物上清液过滤后混合得药物原液，再 加入二甲基亚砜（DMSO)，比例为药物原液100 ： 0.5〜1的二甲基亚砜即可制得涂抹剂。
[0009] 涂抹剂药物原液用蒸馏水2-5倍稀释，可得到不同浓度的稀释液，用于其它剂型， 浓缩的药物原液用于储备、勾兑使用。例如，将药物原液加蒸馏水2倍，稀释制成喷剂；将药 物原液加蒸馏水5倍稀释制成洗发液。
[0010] 涂抹剂的用法用量：洗发后将涂抹剂均勻搽抹于脱发局部，可每天两次。
[0011] 喷剂：每天可多次喷涂于脱发局部。
[0012] 洗液：正常洗发后再用本药液漂洗，揉搓1〜2分钟，效果更好。
Claims (4)
1. 一种治疗脱发的外用复方中药涂抹剂，以天然植物为原料，原料分两部分，其特征在 于药物组份的重量比为：（1)人参1〜3份、何首乌1〜3份、黄芪1〜3份、柏子仁1〜3 份、当归1〜3份、补骨脂1〜3份、茯苓1〜3份、桃仁1〜3份、红花1〜3份、干姜1〜 3份；⑵枣树枝4〜10份、松树枝4〜10份、桃树枝4〜10份、柳树枝4〜10份、大蒜 4〜10份、侧柏叶10〜20份、桑叶10〜20份、皂角10〜20份。
2. —种权利要求1所述治疗脱发的外用复方中药涂抹剂的制备方法，其特征在于按所 述原料药物组份重量比，分别将原料（1)和（2)粉碎、过筛200目，将粉末状的原料（1)混 合物放入玻璃容器中用浓度45%乙醇酒浸泡7天，将粉末状的原料（2)混合物按药水容积 比1 ： 2加入蒸馏水，浸泡24小时后煮沸，然后放入玻璃容器中加入乙醇，使乙醇终浓度达 到10%，浸泡5天，每天用木棍分别对原料（1)和（2)混合物搅拌一次，温度保持在20-25°C 之间；经分别过滤后，将（1)和（2)的混合物上清滤液混合后获得药物原液，加入重量比为 原液100 ： 0.5〜1的二甲基亚砜即可制得涂抹剂。
3. 一种治疗脱发的外用复方中药喷剂的制备方法，其特征在于：药物组份的重量比 为：（1)人参1〜3份、何首乌1〜3份、黄芪1〜3份、柏子仁1〜3份、当归1〜3份、补 骨脂1〜3份、茯苓1〜3份、桃仁1〜3份、红花1〜3份、干姜1〜3份；（2)枣树枝4〜 10份、松树枝4〜10份、桃树枝4〜10份、柳树枝4〜10份、大蒜4〜10份、侧柏叶10〜 20份、桑叶10〜20份、皂角10〜20份；按上述原料药物组份重量比，分别将原料（1)和 (2)粉碎、过筛200目，将粉末状的原料（1)混合物放入玻璃容器中用浓度45%乙醇酒浸 泡7天，将粉末状的原料（2)混合物按药水容积比1 ： 2加入蒸馏水，浸泡24小时后煮沸， 然后放入玻璃容器中加入乙醇，使乙醇终浓度达到10%，浸泡5天，每天用木棍分别对原料(1)和（2)混合物搅拌一次，温度保持在20-25°C之间；经分别过滤后，将（1)和（2)的混合 物上清滤液混合后获得药物原液，加入蒸馏水2倍，稀释制成喷剂 。
4. 一种治疗脱发的外用复方中药洗发液的制备方法，其特征在于：药物组份的重量比 为：⑴人参1〜3份、何首乌1〜3份、黄芪1〜3份、柏子仁1〜3份、当归1〜3份、补 骨脂1〜3份、茯苓1〜3份、桃仁1〜3份、红花1〜3份、干姜1〜3份；(2)枣树枝4〜 10份、松树枝4〜10份、桃树枝4〜10份、柳树枝4〜10份、大蒜4〜10份、侧柏叶10〜 20份、桑叶10〜20份、皂角10〜20份；按上述原料药物组份重量比，分别将原料（1)和(2)粉碎、过筛200目，将粉末状的原料（1)混合物放入玻璃容器中用浓度45%乙醇酒浸 泡7天，将粉末状的原料（2)混合物按药水容积比1 ： 2加入蒸馏水，浸泡24小时后煮沸， 然后放入玻璃容器中加入乙醇，使乙醇终浓度达到10%，浸泡5天，每天用木棍分别对原料 (1)和（2)混合物搅拌一次，温度保持在20-25°C之间；经分别过滤后，将（1)和（2)的混合 物上清滤液混合后获得药物原液，加入蒸馏水5倍，稀释制成洗发液。
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