CN101138391B - Feed additive and preparing method thereof - Google Patents
Feed additive and preparing method thereof Download PDFInfo
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- CN101138391B CN101138391B CN2006101070134A CN200610107013A CN101138391B CN 101138391 B CN101138391 B CN 101138391B CN 2006101070134 A CN2006101070134 A CN 2006101070134A CN 200610107013 A CN200610107013 A CN 200610107013A CN 101138391 B CN101138391 B CN 101138391B
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Landscapes
- Fodder In General (AREA)
Abstract
The present invention relates to a feed additive and the preparation method; the present invention is characterized in that the additive is prepared with components of the following weights that 3000 to 5000 shares of milkvetch root, 700 to 900 shares of areca, 1500 to 3000 shares of hawthorn, 1000 to 2000 shares of ferrous sulphate, 8 to 15 shares of sodium nitrate, 800 to 1200 shares of vitamin E powder with a 50-percent content, 800 to 1500 shares of seasoning peptide, 200 to 400 shares of flavor agent and 1500 to 2500 shares of pure vitamin C powder. The combination of components of the present invention is to regulate the conflict between the animal nutrition and disease; on the basis of national unique theory of the Chinese traditional medicine made of natural plant, the present invention integrates modern technology to select the Chinese traditional medicine made of natural plant and the study of composition and chelation is implemented on the Chinese traditional medicine; the iron-selenium chelate complex in the Chinese traditional medicine made of natural plant and the feed integral nutrition are taken into uniform consideration; the seasoning peptide and vitamin are added as adjuvant to enhance the effect of the iron-selenium chelate complex. The iron-selenium chelate complex in the Chinese traditional medicine made of natural plant, as a feed additive, has the functions of health care and nutrition; in this way, the present invention can prevent disease and promote production performance.
Description
Technical field
The present invention relates to a kind of feed addictive, simultaneously, also relate to a kind of preparation method of this feed addictive.
Background technology
Current, animal such as bird flu, aftosa deadly infectious disease also in transnational popular, domestic zoonosis also complicated, people are badly in need of putting out and controlling these infectious diseases, above-mentioned situation occurs, be mostly because immune level and the nutrition condition of animal have occurred unbalance.Exist very close getting in touch between disease and the nutrition, from " nutrition immune " of animal, body's immunological function and the Animal nutrition situation that the resistance of disease is affected; From animal " nutritional physiology ", the nutritional need pattern of animal affects the health status of body again.Along with the development of aquaculture scale, specialization, commercial running, excrement that domestic animal is discharged and urine have become the severe contamination source of water quality and soil, directly threaten industrial and agricultural production and human health.Along with the reinforcement of various countries environment department and the activity of relevant environment group, national governments have formulated very strict environmental legislation.Present China implements " feed safety " engineering and (comprises the feeding quality monitoring system, the feed safety appraisement system, feed safety monitoring and prediction network center three parts in station), the Ministry of Agriculture organizes and implements the action plan of " pollution-free food ", and " 15 " tackling of key scientific and technical problems of country also will solve feed safety evaluation and detection technique.For the sustainable development of aquaculture, must hang down the public hazards feed addictive by the research and development green non-pollution, make aquaculture change enviromental protection enterprise into by environmental pollution enterprise.Therefore, aquaculture is badly in need of a kind of green feed additive that collects immunologic function and trophic function.
In recent years, on the problem that solves disease and nutrition, everybody has carried out many useful exploration and practices, except that using a part of antibiotic, considers more just to use chemical synthesis class additive.In last century, chemical synthesis class Application of Additives increases considerably the output of China's pork, and the part antibiotic has some improvement to the quality of meat, thereby obtains comparatively considerable economic.But its toxic and side effect also is subject to people's attention day by day, as antibiotic drug resistance and residual, and in animal body residual of hormone, heavy metal, all direct health of harm humans.And also have " three cause " phenomenon to take place, human more and more higher to the requirement of quality of life.Along with Developing of Animal Industry, the breach of complicated and China's green feed additive of livestock and poultry is with in rising trend.In addition, also exist bigger gap between the raise competence of China and the international environment, with regard to the NRC standard, the average feed intake of China pig is lower by 10%～35% than NRC standard, thereby has directly caused the level of production of pig lower.At present; how to promote the speed of growth of livestock and poultry, the immunologic function that watches for animals, improve the digestibility and utilization efficient of animal, improve the livestock products quality, reduce medicament residue, reduce gradually even forbid the antibiotic etc feed addictive, produce that green livestock products becomes China's animal husbandry and feed industry presses for one of problem of solution most.
Summary of the invention
At the problems referred to above, the object of the present invention is to provide a kind of feed addictive, with the digestibility and utilization efficient of the speed of growth that promotes livestock and poultry, the immunologic function that watches for animals, raising animal, and improve livestock products quality, minimizing medicament residue.
Simultaneously, the present invention also aims to provide a kind of preparation method of this feed addictive.
To achieve these goals, technical program of the present invention lies in having adopted a kind of feed addictive, comprise following compositions in weight portion and be prepared from:
Radix Astragali 3000-5000 part betel nut 700-900 part hawthorn 1500-3000 part
Ferrous sulfate 1000-2000 part sodium selenite 8-15 part 50% vitamin E powder 800-1200 part
Seasoning peptide 800-1500 part tasty agents 200-400 part pure vitamin C powder 1500-2500 part.
Described seasoning peptide by fragrance peptide, sweet taste peptide and healthy peptide by the fragrance peptide: the sweet taste peptide: the proportioning of healthy peptide=1: 1: 2 mixes.
Described fragrance peptide is: 5 '-Sodium guanylate (C
10H
12N
5Na
2O
8P).
Described sweet taste peptide is: 2-L-aspartyl-L-phenylalanine methyl esters (C
14H
18N
2O
5).
Described healthy peptide is: that western peptide (C
51H
43N
13O
12S
6).
Described tasty agents is: the flavour nucleotide disodium.
Simultaneously, technical program of the present invention also lies in adopting a kind of preparation method of this feed addictive, may further comprise the steps:
(1) Chinese herbal medicine lixiviate: after the impurity elimination respectively of Chinese herb astragalus, betel nut, hawthorn, pulverizing, mix, and feed steam and size mixing, when being warming up to 80-90 ℃, the active ingredient organic acid in the Chinese herbal medicine, amino acid lixiviate are come out;
(2) Chinese herbal medicine and inorganic iron selenium chelating: with Chinese herbal medicine leaching liquor, reduce the temperature to 45 ℃, add hydrochloric acid and regulate pH, add ferrous sulfate and sodium selenite again, chelatropic reaction 15-20 hour continuously to 4.0-5.5;
(3) fortification of Chinese herbal medicine iron selenium chelate: seasoning peptide, flavour nucleotide disodium and vitamin C and 50% vitamin E powder are joined in the Chinese herbal medicine iron selenium chelate, get final product finished product.
The performance of each component is as follows in the additive of the present invention: the Radix Astragali, claim cotton stilbene again, be simply invigorating qi for strengthening superficies, the holder necrotic tissue and promoting muscle growing Chinese herbal medicine, modern pharmacological research thinks, the Radix Astragali has the generation that promotes haemocyte and leukocytic phagocytic activity, anticancer, antiviral and improve the effect that body T lymphocyte and bone-marrow-derived lymphocyte generate.Betel nut can suppress tumor growth; Can make pork tapeworm that flaccid paralysis takes place; Pinworm also there is the paralysis effect; Gastrointestinal smooth muscle tension force is raise, increase enterocinesia, digestive juice secretion is vigorous, and appetite increases; The excited M of arecaline energy, two kinds of choline receptors of N have the effect of the choline of plan to central nervous system; Fungi there is inhibitory action in various degree; The resisiting influenza virus effect is arranged.Hawthorn: can strengthen protease activities in the stomach, promote digestion, its contained lipase also can promote the digestion of fatty dyspepsia; Hawthorn contains how lipase of acetic acid, can effectively improve T lymphocyte transformation rate and serum lysozyme content a-ANAE, can improve immunity.Vitamin C participates in the redox reaction of metabolism in vivo, and very easily oxidative dehydrogenation has strong reducing property, and the sulfhydryl-group activity of protective enzyme is not destroyed by poisonous substance; Participate in the synthetic of matter between collagen and histocyte simultaneously; Think at present vitamin C have strengthen body resistance against diseases, in and the effect that generates and strengthen leukocytes phagocytic ability and liver detoxification function of bacterial endotoxin, raising serum immune globulin content, enhancing antibody, especially the infected animal and the animal rapidly that grows increase rapidly to ascorbic demand.Trace elements iron selenium participates in carrier and forms, transports and the storage nutrient; Participate in the substance in vivo metabolism; Participate in physiology defence function.And the effect of prevention organism infection disease arranged.The seasoning peptide is fragrance peptide, sweet taste peptide, healthy peptide three's a mixture, the effect of seasoning peptide can reduce following some: effectively cover bad smell in the feed, improve the feed palatability, improve feed quality; Be beneficial to the new feed resource of exploitation, reduce feed cost; It is more flexible that daily ration is cooperated; Have strong attractant, improve a poor appetite, strengthen feed intake; Overcome various stress, strengthen premunition; Strengthen digestive system function, improve food conversion ratio.Tasty agents, the flavour nucleotide disodium is white crystals or powder, the flavour nucleotide disodium enters in the body, participates in the animal body metabolism with nucleotides, glutamic acid and sodium.Glutamic acid to the albumen of animal body reproduce, reparation and growth pole be important; Glutamic acid is required amino acid whose a kind of of animal body, and wherein 96% can be absorbed by animal body, forms the protein in the animal body tissue, plays in animal body and improves and the effect of maintenance cerebral function; Other amino acid can become new amino acid to amino by glutamic acid rotating, make animal body increase amino acid whose kind, help the synthetic of protein.Transamination is the rely process of synthetic various amino acids of animal body, and therefore, the flavour nucleotide disodium has great importance for the synthetic of amino acid in the animal body body.All compositions of the present invention share, mainly be the contradiction between regulation and control Animal nutrition and the disease, on the basis of the natural vegetable Chinese herbal medicine rerum natura theory that China creates, in conjunction with modern science and technology, natural vegetable Chinese herbal medicine is screened and carries out the research of compatibility and lixiviate chelating, and, add seasoning peptide, vitamin as adjuvant, to strengthen its effect with natural vegetable Chinese herbal medicine iron selenium chelate and the unified consideration of the whole nutrition of feed.Chinese herbal medicine iron selenium chelate has health care and nutrition double action concurrently as feed addictive, and both preventable disease can improve production performance again.The main component of hawthorn is organic acid, amino acid and flavone compound, and wherein organic acid has crataegolic acid, citric acid, malic acid, butanedioic acid etc.; The Radix Astragali contains a large amount of amino acid, geranic acid, aminobutyric acid, saponin and legumin etc.These organic acids can close with mineral element a flat iron plate for making cakes such as inorganic iron, selenium under certain conditions, make the latter by inorganic become organic.
Simultaneously, also contain anti-(pressing down) bacterium composition in the Chinese herbal medicine of the present invention, bioactivators such as alkaloid, polysaccharide, glucoside, volatile oil, tannin, the mineral matter, vitamin, unknown growth regulator and the pigment that also contain some, thereby can improve the premunition of body by the effect of antibacterial material and immunologic active material.Polysaccharide is immunocompetent main matter, has the reaction of the thymus gland of promotion, stimulates the phagocytic function of macrophage; Glucoside can be strengthened the reticuloendothelial system phagocytic function, and energy enhancing antibody antigen-reactive and lymphocyte transformation; Organic acid in the Chinese herbal medicine can be regulated the pH value in the stomach and intestine, prevents the breeding of harmful bacteria and the activity of raising enzyme, promotes normal metabolic in the animal body, thereby improves the utilization rate of nutriment, has promoted the performance of breeding performonce fo animals.From " nutrition immune " principle analysis, Chinese herbal medicine iron selenium chelate, seasoning peptide, vitamin E, vitamin C can improve the effect of body T lymphocyte and bone-marrow-derived lymphocyte generation, promote macrophage to form, with enhancing body's immunological function; From " nutrition endocrinology " principle analysis, seasoning peptide and flavour nucleotide disodium can promote the secretion of animal digestion liquid by the regulation and control of body endogenous, improve the desire of searching for food, and increase the feed intake of animal, promote growth of animal.
The present invention is by to " nutritional physiology ", " nutrition immune " of animal, the analysis that " nutrition endocrinology " carries out, use Chinese herbal medicine iron selenium chelate, vitamin, phagostimulant etc. to regulate and control the immune system of animal and the system of searching for food, thereby keep microecological balance in the animal body, promote to search for food, guaranteed growing up healthy and sound and the green of livestock products, nuisanceless of animal.Additive of the present invention not only can improve the immunologic function of animal, but also can improve the feed intake of animal, belongs to green biological feedstuff, help the healthy and growth of animal, the trend that meets green cultivation has favorable social and economic worth, is easy to apply.
Method of the present invention is with behind the Chinese herbal medicine rational proportion, carries out lixiviate earlier, treat that its amino acid, organic acid discharge after, carry out the physics and chemistry chelating with inorganic iron selenium again, make inorganic microelement be transformed into organic trace element, effect obviously improves.The present invention comes out the amino acid in the Chinese herbal medicine, organic acid lixiviate, carry out chelating with inorganic microelement again, for the development and application of China's Chinese herbal medicine a brand-new research field, for improving trace element utilizing rate, reduce environmental pollution and opened up a new approach, extremely important meaning is arranged promoting China's feed industry technical merit with the raising growth of animal.
The specific embodiment
Embodiment 1
Feed addictive of the present invention, comprising following compositions in weight portion is prepared from: 3000 parts of the Radixs Astragali, 700 parts of betel nuts, 1500 parts of hawthorn, 1000 parts in ferrous sulfate, 8 parts of sodium selenites, 800 parts of 50% vitamin E powders, 800 parts of seasoning peptides, 200 parts of flavour nucleotide disodiums, 1500 parts in pure vitamin C powder.
Wherein the seasoning peptide is by fragrance peptide 5 '-Sodium guanylate (C
10H
12N
5Na
2O
8P), sweet taste peptide 2-L-aspartyl-L-phenylalanine methyl esters (C
14H
18N
2O
5) and that western peptide (C of healthy peptide
51H
43N
13O
12S
6) by the fragrance peptide: the sweet taste peptide: the proportioning of healthy peptide=1: 1: 2 mixes.
Its preparation method may further comprise the steps:
(1) Chinese herbal medicine lixiviate: after the impurity elimination respectively of Chinese herb astragalus, betel nut, hawthorn, pulverizing, mix, and feed steam and size mixing, when being warming up to 80 ℃, the active ingredient organic acid in the Chinese herbal medicine, amino acid lixiviate are come out;
(2) Chinese herbal medicine and inorganic iron selenium chelating: with Chinese herbal medicine leaching liquor, reduce the temperature to 45 ℃, add hydrochloric acid and regulate pH to 4.0, add ferrous sulfate and sodium selenite again, chelatropic reaction is 15 hours continuously;
(3) fortification of Chinese herbal medicine iron selenium chelate: seasoning peptide, flavour nucleotide disodium and vitamin C and 50% vitamin E powder are joined in the Chinese herbal medicine iron selenium chelate, get final product finished product.
Embodiment 2
Feed addictive of the present invention, comprising following compositions in weight portion is prepared from: 4000 parts of the Radixs Astragali, 800 parts of betel nuts, 2000 parts of hawthorn, 1500 parts in ferrous sulfate, 12 parts of sodium selenites, 1000 parts of 50% vitamin E powders, 1200 parts of seasoning peptides, 300 parts of flavour nucleotide disodiums, 2000 parts in pure vitamin C powder.
Wherein the seasoning peptide is by fragrance peptide 5 '-Sodium guanylate (C
10H
12N
5Na
2O
8P), sweet taste peptide 2-L-aspartyl-L-phenylalanine methyl esters (C
14H
18N
2O
5) and that western peptide (C of healthy peptide
51H
43N
13O
12S
6) by the fragrance peptide: the sweet taste peptide: the proportioning of healthy peptide=1: 1: 2 mixes.
Its preparation method may further comprise the steps:
(1) Chinese herbal medicine lixiviate: after the impurity elimination respectively of Chinese herb astragalus, betel nut, hawthorn, pulverizing, mix, and feed steam and size mixing, when being warming up to 85 ℃, the active ingredient organic acid in the Chinese herbal medicine, amino acid lixiviate are come out;
(2) Chinese herbal medicine and inorganic iron selenium chelating: with Chinese herbal medicine leaching liquor, reduce the temperature to 45 ℃, add hydrochloric acid and regulate pH to 5.0, add ferrous sulfate and sodium selenite again, chelatropic reaction is 18 hours continuously;
(3) fortification of Chinese herbal medicine iron selenium chelate: seasoning peptide, flavour nucleotide disodium and vitamin C and 50% vitamin E powder are joined in the Chinese herbal medicine iron selenium chelate, get final product finished product.
Embodiment 3
Feed addictive of the present invention, comprising following compositions in weight portion is prepared from: 5000 parts of the Radixs Astragali, 900 parts of betel nuts, 3000 parts of hawthorn, 2000 parts in ferrous sulfate, 15 parts of sodium selenites, 1200 parts of 50% vitamin E powders, 1500 parts of seasoning peptides, 400 parts of flavour nucleotide disodiums, 2500 parts in pure vitamin C powder.
Wherein the seasoning peptide is by fragrance peptide 5 '-Sodium guanylate (C
10H
12N
5Na
2O
8P), sweet taste peptide 2-L-aspartyl-L-phenylalanine methyl esters (C
14H
18N
2O
5) and that western peptide (C of healthy peptide
51H
43N
13O
12S
6) by the fragrance peptide: the sweet taste peptide: the proportioning of healthy peptide=1: 1: 2 mixes.
Its preparation method may further comprise the steps:
(1) Chinese herbal medicine lixiviate: after the impurity elimination respectively of Chinese herb astragalus, betel nut, hawthorn, pulverizing, mix, and feed steam and size mixing, when being warming up to 90 ℃, the active ingredient organic acid in the Chinese herbal medicine, amino acid lixiviate are come out;
(2) Chinese herbal medicine and inorganic iron selenium chelating: with Chinese herbal medicine leaching liquor, reduce the temperature to 45 ℃, add hydrochloric acid and regulate pH to 5.5, add ferrous sulfate and sodium selenite again, chelatropic reaction is 20 hours continuously;
(3) fortification of Chinese herbal medicine iron selenium chelate: seasoning peptide, flavour nucleotide disodium and vitamin C and 50% vitamin E powder are joined in the Chinese herbal medicine iron selenium chelate, get final product finished product.
It should be noted last that: above embodiment is the unrestricted technical scheme of the present invention in order to explanation only, although the present invention is had been described in detail with reference to the foregoing description, those of ordinary skill in the art is to be understood that: still can make amendment or be equal to replacement the present invention, and not breaking away from any modification or partial replacement of the spirit and scope of the present invention, it all should be encompassed in the middle of the claim scope of the present invention.
The feeding experiment of additive of the present invention and application study
Test the test report of a feed addictive of the present invention (it the is upright strong to live) weanling pig of feeding
To found strong actual feeding effect as feed addictive in order inquiring into to live, and to find out its optimum addition, we carry out this test hereby.
One. experimental animal and grouping
From Woyang, Anhui ten thousand pig farms choose 30 ages in days, body weight (200 of 7.95 ± 0.57kg) close healthy DLY piglets, male and female half and half, by size, sex phase approximately principle is divided into 4 groups at random, every group 48, establish 6 repetitions for every group, each repeats 8, and is standby during remaining 8 piglets are raised in advance.
Two. the experimental animal daily ration is formed and nutrition
6 groups of piglet basal diets are identical, are powder, add 0% (blank group, 0.0gkg-1), 0.25% (2.5gkg-1), 0.50% (5.0gkg-1), 0.75% (7.5gkg-1) upright being good for alive respectively.Daily ration mixes, and the coefficient of variation is less than 8% after measured, and feedstuffs such as its corn, dregs of beans, fish meal meet GB (GB13078-2001) quality requirement after testing.The daily ration configuration is with reference to G GB GB/T5915 piglet, grow-finish swine feed standard, and it is formed and nutrition sees Table 1.
Table 1. test piglet basal diet is formed and trophic level %
Annotate: contain 20% lysine, vitamin and trace element etc. in the experimental period premix.
By following table 2 results as can be seen, feed addictive of the present invention (live upright strong) can obviously improve the daily gain (P＜0.05) of weanling pig, has improved feed intake (P＞0.05 or P＜0.05), feed conversion rate also decrease (P＞0.05).Do not add upright strong the comparing of living with control group, make the pork pig daily gain improve 10.28%, 9.15% and 12.23% respectively whole test phase (30-98 age in days) upright being good for alive, feed intake has improved 5.02%, 4.61% and 6.89% respectively, and feed conversion rate has reduced by 4.40%, 4.00% and 4.80% respectively.
Table 2. is lived and is stood strong influence to the weanling pig production performance
Annotate: a, b represent 4 groups of upright significances of difference (P＜0.05) of being good for production performance index between the interpolation level of work in the identical age in days, and the production performance index is not made comparisons in the different days.Following table herewith.
The upright strong stimulating growth effect of living may have certain relation with the pork pig growth phase, and the early stage stimulating growth effect that weans is much better.When the upright strong addition of living is 0.25%, 0.50%, 0.75%, 30-68 age in days pork pig daily gain has improved 14.89%, 16.01% and 16.47% (P＜0.05) respectively, feed intake has improved 8.87%, 11.45% and 8.84% (P＜0.05) respectively, feed conversion rate has reduced by 5.24%, 3.93% and 6.55% (P＞0.05) respectively, and the growth promotion effect is obvious.Upright being good for of living during the 68-98 age in days makes the pork pig daily gain improve 7.45%, 4.93% and 11.35% (P＞0.05) respectively, feed intake has improved 2.95%, 0.94% and 5.84% (P＞0.05) respectively, feed conversion rate has reduced by 4.18%, 3.80% and 4.94% (P＞0.05) respectively, but all not remarkable.
The result it can also be seen that by table 2, living, it is very little to promote growth and improve the efficiency of feed utilization difference on effect between upright strong 0.25%, 0.50%, 0.75% additive capacity, be higher than 0.25% dosage and do not see that the synergy phenomenon is arranged, results suggest upright strong optimum addn amount alive may be 0.25%.
Table 3. is lived and is stood strong influence to weanling pig health status
The result it can also be seen that by table 3, lives in uprightly strongly can improving weanling pig health status, compares with control group and adds live upright strong back death rate (P＜0.05) and all obviously decline (P＜0.01) of diarrhoea index.
Test two feed addictives of the present invention upright strong test report of feeding the DLY piglet alive
In order to put into practice the upright strong feeding effect as additive for feed for piglets of living, we select for use DLY three way cross piglet to do following research, and the result is as follows:
1. materials and methods
1.1 test material
1.1.1 additive of the present invention (it is upright strong to live)
1.1.2 test pig is selected and grouping: close (84 of the DLY three way cross piglets of body weight 18.9 ± 0.85kg) (59 and 60 age in days piglet) of body weight that test pig selects ten thousand kind pig farms, Nanyang to raise, be divided into test group and control group at random, 42 of test group (22 of sows, 20 of boars), 42 of control groups (19 of sows, 23 of boars).Two groups of piglet body weight close (significance analysis is not remarkable), each group is all established 7 repetitions, and each repeats 6.
1.2
Test feed and nutrition: test group is identical with control group piglet basal diet, is powder, and control group does not add upright being good for of living, and it is alive upright strong that test group is pressed per kilogram complete diet pellet interpolation 2.5g, i.e. 0.25% dosage.Daily ration mixes, and the coefficient of variation is less than 8% after measured.Daily ration is configured to G GB GB/T5915 piglet, grow-finish swine feed standard is reference, and it is formed and nutrition sees Table 1.Feedstuffs such as its corn, dregs of beans, wheat bran, imported fish meal meet GB (GB13078-2001) quality requirement after testing.
Table 1. test piglet basal diet is formed and trophic level %
Annotate: contain stone flour, calcium monohydrogen phosphate, salt, 20% lysine, vitamin and trace element etc. in the experimental period premix.
2. result of the test
2.1 weightening finish: the heavy 38.06kg in the average end of 42 piglets of test group, the heavy 35.71kg in the average end of control group, test group has more 2.35kg than control group, has improved 6.58% (P＜0.05); Test group average weight gain 19.24kg, control group average weight gain 16.66kg, test group has more 2.58kg than control group, has improved 15.49% (P＜0.01); Test group average daily gain 356.30g, control group average daily gain 308.52g, test group has more 47.78g than control group, improves 15.49% (P＜0.01).See table 2 for details.
The weightening finish of table 2 test pig comparison sheet unit: kg, g
| Group | Number | The test fate | Starting weight/head/kg | An end weight/kg | Total augment weight/head/kg | Daily gain/head/g |
| Control group | 42 | 54 | 19.05 | 35.71±1.69 | 16.66±1.04 | 308.52±64 |
| Test group | 42 | 54 | 18.82 | 38.06± 2.85* | 19.24± 1.67** | 356.30± 111** |
Annotate: * * represents to be listed as the interior significance of difference (P＜0.01), and * represents to be listed as the interior significance of difference (P＜0.05).Table 2 herewith.
2.2 feed intake and feed conversion rate: every feed intake 45.21kg of test group, every feed intake 40.32kg of control group, test group manys 40.89kg. than control group, and feed intake has increased by 12.13% (P＜0.05); Test group feed conversion rate 2.35 lacks 0.07 than control group 2.42, and test group has reduced by 2.89% (P＞0.05) than control group.See table 3 for details.
Table 3 feed intake, feed conversion rate and feed cost list position: kg, unit
| Group | Number | Weightening finish/head/kg | Feed intake/head/kg | Feed conversion rate | Feed cost/unit | Feed cost/unit // 1kg weightening finish |
| Control group | 42 | 16.66 | 40.32± 1.23 | 2.42± 0.49 | 60.48 | 3.63 |
| Test group | 42 | 19.24 | 45.21± 2.35* | 2.35± 0.83 | 67.82 | 3.52 |
Annotate: press there and then feedstuff calculation of price, 1.508 yuan/kg of feed.
2.3 feed cost
3.52 yuan of test group per kilogram weightening finish feed costs, 3.63 yuan of control group per kilogram weightening finish feed costs, test group descends 0.11 yuan than control group per kilogram weightening finish feed cost, and 3.03% (P＞0.05) has descended.
2.4 clinical observation
The test group pig eats soon than control group pig, honey stomach, and by hair gloss, skin is ruddy, and the fecaluria foul smell alleviates greatly.Test group is morbidity not, and moderate diarrhoea appears in 3 of control groups.
3. conclusion and suggestion
Upright being good for of living can be improved the daily gain of weanling pig, improves feed intake, strengthens premunition, and feed efficiency is improved not obvious.Use is added in suggestion in piglet diet.
The application test of material in the fattening pig daily ration strengthened in test three
1, test objective: this test is studied the influence of reinforcement material to the fattening pig production performance by add reinforcement material " it is upright strong to live " in the fattening pig daily ration.
2, test site: Yichuan County three and pig farm
3, test material and method
3.1 the design of daily ration
The design of table 11 daily ration
| Raw material | Corn | Dregs of beans | Wheat bran | Premix | DE(MJ/kg) | CP(％) | Lys(％) |
| The daily ration proportioning | 600 | 170 | 190 | 40 | 13.16 | 17.0 | 0.83 |
Add 0.25% reinforcement material " it is upright strong to live " in the test group, do not add in the control group and strengthen material, all the other raw material proportionings are identical.
3.2 selection and the grouping of test swinery
Selective body focuses on about 60 kilograms, and kind is 100 of the ternary market pigs of DLY, adjusts male and female by former hurdle as far as possible and divides equally.Be divided into two groups at random, 50 every group.Test period 35 days.
3.3 feeding and management
Test swinery free choice feeding dry mash is freely drunk water, and regularly cleans health in the hurdle every day, keeps clean.Other daily managements are carried out routinely.
3.4 detection index
Weigh record weight, dead situation and feed intake, ultimate analysis swinery daily gain, feed conversion rate and the survival rate of washing in a pan of record every day the whole story respectively on an empty stomach in test.
4, result and analysis
4.1 result of the test
Table 12 result of the test
| Project | Control group | Test group |
| Number (head) | 50 | 50 |
| Initial weight (kg) | 3012.0 | 3003.0 |
| End weight (kg) | 4375.25 | 4418.75 |
| Total feed consumption rate (kg) | 4147.50 | 4060.0 |
| Average daily ingestion amount (kg) | 2.37 | 2.32 |
| Total augment weight (kg) | 1363.25 | 1415.75 |
| Average daily gain (g) | 779 | 809 |
| Efficiency of feed utilization | 3.04∶1 | 2.87∶1 |
| The incidence of disease (%) | 8 | 0 |
As seen from the above table, the control group daily gain is 779 grams, and test group is 809 grams, and test group has improved 3.85% than control group; The control group efficiency of feed utilization is 3.04: 1, and test group is 2.87: 1, and test group has improved 5.6% than control group; The average daily ingestion amount of control group is 2.37 kilograms, 2.32 kilograms of test group average out to, and test group has improved 2.1% than control group.
4.2 Economic and Efficiency Analysis
Table 13 Economic and Efficiency Analysis
| Group | Feed unit price (unit/kilogram) | Efficiency of feed utilization | Cost per gain weight (unit/kilogram) |
| Control group | 1.72 | 3.04 | 5.23 |
| Test group | 1.77 | 2.87 | 5.08 |
As seen from the above table, the test group cost per gain weight is lower 0.15 yuan/kilogram than control group, has reduced by 2.86%, remarkable in economical benefits.
5, brief summary
From analysis result as seen, test group is compared with control group, all is being improvement trend aspect daily gain, daily ingestion amount and the feed conversion rate, and the test group cost per gain weight has reduced by 2.86% than control group.This shows that strengthening material " it is upright strong to live " has good using value aborning.Organic principle in " it is upright strong to live " has improved the feed intake of animal by the endogenous regulation and control, and Chinese herbal medicine, marine product extract can change microorganism species in the alimentary canal, suppress or the kill harmful bacterium, improve the utilization rate of nutrient.Strengthen material " it is upright strong to live " by above some comprehensive function, improved the speed of growth of fattening pig, reduced cost per gain weight.
Test top four material is raised the effect research of lactating sow
1, test objective: this test is studied the influence of reinforcement material to sow production performance by add reinforcement material " it is upright strong to live " in the sow daily ration.
2, test site: Da Yang pig farm, Linzhou City
3, experimental design
3.1 experimental animal and grouping
Select blood relationship, parity, body weight the grow up lactating sow 20 close with the farrowing date, the sow head all is with young several 10.5, and 220 kilograms of sow counterpoises are divided into 2 groups (control group and test group) at random.Add 0.25% reinforcement material " it is upright strong to live " in the test group material, do not add in the control group and strengthen material, basal diet is identical.
3.2 basal diet prescription
Table 14 diet is formed and trophic level
| Raw material is formed | Content (%) | Nutritional labeling | Content |
| Corn | 62 | Digestible energy (kcal/kg) | 3185 |
| Wheat bran | 8 | Crude protein (%) | 16.8 |
| Dregs of beans | 18 | Calcium (%) | 1.03 |
| The angle powder | 2 | Total phosphorus (%) | 0.64 |
| Rice bran | 6 | Lysine (%) | 0.81 |
| Premix | 4 |
3.3 feeding and management
35 days (oestrusing once more from farrowing) carried out in test, raises by the conventional feeding manner in pig farm.Wet-mixing material free choice feeding is freely drunk water.When on-test and end, every group is carried out individuality and weighs calculating bulk diffusion, statistics feed intake and weight gain of piglets situation.
3.4 test event
Sow feed intake every day, the sow changes of weight, piglet birth litter weight and weight of weaning litter, postweaning estrus is fate at interval.
4, result of the test and analysis
Add in the feed to strengthen and expect that " it is upright strong to live " sees Table 15 to the influence of sow feed intake.After adding the reinforcement material in the daily ration, sow 8-28 days feed intake was increased to 5.5kg/ days by 5.0kg/ days, increased by 10.0%, and the body weight of yet observing sow does not simultaneously have tangible loss.Adding reinforcement expects the influence of piglet production performance is seen Table 16.Test group improves 10.45% than control group average weight during wean; The sow body weight loss reduces by 33.3%; The fate of oestrusing was reduced to 6.0 days by 6.5 days, shortened 0.5 day.
The influence of table 15 pair sow feed intake and body weight
| The farrowing back 0-7 top margin of a page equal feed consumption kg/ days | The farrowing back 8-28 top margin of a page equal feed consumption kg/ days | Feed intake increases kg/ days | Body weight loss situation kg/ head | The diestrum sky | |
| Control group | 3.2 | 5.0 | 12 | 6.5 | |
| Test group | 4.3 | 5.5 | 0.5 | 8 | 6.0 |
The influence of table 16 pair piglet production performance
| Equal starting weight (kg) | Wean end heavy (kg) | Weightening finish (kg) | Many weightening finishes (kg) | The incidence of disease (%) | |
| Control group | 1.35 | 6.7 | 5.35 | 8.3 | |
| Test group | 1.3 | 7.4 | 6.1 | 0.75 | 1.2 |
5, Economic and Efficiency Analysis
Piglet 12 yuan/kg is at market price calculated, and every piglet has a net increase of 9 yuan of profits, shortens the fate 0.5 day of oestrusing, and shortens i.e. whole production cycle in advance in oestrous cycle, and the economic benefit of being brought is very remarkable.
6, discuss
After adding reinforcement material " it is upright strong to live " in the feed, the feed intake of sow is with respect to control group improve 10.0%.Because the feed intake of sow increase, nutrition are taken in and increased, lactation amount increases, and the daily gain that drives piglet increases, and has improved weight of weaning litter, for later fattening stage is laid a good foundation.
The deficiency if lactating sow is searched for food, sow will consume from bodily tissue, and the piglet litter weight also can reduce.When energy was under-supply, fat can be consumed; If the back fat attenuation, musculature can be consumed to satisfy energy requirement.The consumption of these two kinds of somas can make back fat and lose weight, directly the time interval of oestrusing again after the influence wean.Therefore, improve the premunition of sow between lactation period, increase the feed intake of sow, it is very important fully satisfying its nutritional need.
The sow material adds reinforcement material " it is upright strong to live ", significantly increases the feed intake of sow, improves resistance, the increase growth in piglets performance of piglet simultaneously, has a wide range of applications.
The application test of material in piglet diet strengthened in test five
1, test objective: weaned behind the weaned piglet multi-stress stress influence, bad phenomenon such as feed intake deficiency, delayed growth appear.This test is studied the influence to piglet feed intake, production performance by add reinforcement material " it is upright strong to live " in the weanling pig daily ration.
2, test site: pig farm, Puyang County later Chao Dynasty village
3, test material and method
3.1 the selection of test pig and grouping: select grow up 60 of binary piglets of 35 ages in days, by randomly assigne it is divided into test group and control group, 20 every group.
3.2 daily ration and trophic level (%)
Table 2 daily ration and trophic level (%)
| Grouping | Corn | Dregs of beans | Wheat bran | Fish meal | Premix | It is upright strong to live | DE | CP | Ca | P | Lys |
| Control group 1 | 62 | 26 | 5 | 3 | 4 | 13.5 | 19.40 | 0.93 | 0.66 | 1.10 | |
| Control group 2 | 62 | 26 | 5 | 3 | 4 | 13.5 | 19.40 | 0.93 | 0.66 | 1.10 | |
| Test group | 62 | 26 | 5 | 3 | 4 | 0.25 | 13.5 | 19.4 | 0.93 | 0.66 | 1.10 |
3.3 trial
Test is carried out in the closed pig house of batch production, and piglet is raised at high bed lactation, changes the group during wean of 35 ages in days and raises in the cement flooring, and the immunity of duration of test piglet, sterilization, swine disease control are all undertaken by the hypervisor of industrial pig standard.Feed 5 every day, freely drinks water.Clean colony house every day 2 times.Test is divided into 7 days phases of raising in advance, formal test 30 days.
4. test results and analysis
4.1 result of the test
Table 3 result of the test unit: kilogram
| Grouping | Head is starting weight all | Head all end is heavy | Head is weightening finish all | Daily gain | Head is feed consumption all | Average daily ingestion amount | Efficiency of feed utilization | The incidence of disease (%) |
| Test group | 9.45±0 .99 | 19.12±2 .51 | 9.67±1 .87 | 0.322 a | 19.27 a | 0.54 a | 1.68 a | 0 |
| Control group 1 | 9.44±0 .95 | 17.87+2. 20 | 8.43±1 .70 | 0.281 b | 18.11 b | 0.50 b | 1.78 b | 5 |
| Control group 2 | 9.36±0 .82 | 17.62+2. 02 | 8.26±1 .62 | 0.275 b | 18.03 b | 0.50 b | 1.82 b | 0 |
Annotate: the different persons of shoulder mark represent significant difference in the same row
As can be seen from the table, the daily gain of test group is 322 grams, and the daily gain of control group is respectively 281 grams, 275 grams, and test group comparison you can well imagine high 14.6%, 17.1% according to component; The efficiency of feed utilization test group is 1.68, and control group is respectively 1.78,1.82, and test group has improved 5.6%, 7.7% than control group, statistical analysis, significant difference (P＜0.05); The average daily ingestion amount of test group is 0.54 kilogram, and the average daily ingestion amount of control group is 0.50 kilogram, and test group increases by 0.04 kilogram than control group, has improved 8%; The incidence of disease of test group is zero, and the incidence of disease of control group is 5%.
4.2 Economic and Efficiency Analysis
Table 4 Economic and Efficiency Analysis
| Group | Feed unit price (unit/kilogram) | Efficiency of feed utilization | Cost per gain weight (unit/kilogram) |
| Control group 1 | 2.15 | 1.78 | 3.83 |
| Control group 2 | 2.15 | 1.82 | 3.91 |
| Test group | 2.17 | 1.68 | 3.65 |
As seen from the above table, the test group cost per gain weight is lower 0.18 yuan/kilogram and 0.26 yuan/kilogram than control group, has reduced by 4.70%, 6.65%, and economic benefit is very remarkable.
5. discuss and brief summary
5.1 observe in the test, pig only grows well, good bloom, and skin is ruddy, and is physically fit, and visible feed addictive of the present invention has played very big effect to piglet growth.
5.2 result of the test shows that " it is upright strong to live " improves daily gain to piglet and efficiency of feed utilization has significant effect, is worth using aborning.
5.3 feed addictive of the present invention " it is upright strong to live " can improve the economic benefit of raising pigs, and is green additive rare in the pig industry.
5.4 this test is to carry out in the summer of heat sweltering heat, various in addition vaccine injections stress be bigger to pig, undoubtedly daily gain had certain influence.
The application test of material in little swine rations strengthened in test six
1, test objective: strengthen the influence of material " it is upright strong to live " to little pig feed intake, premunition, production performance.
2, test site: Da Yang pig farm, Linzhou City
3. test material and method
3.1 experimental animal and experimental design: select 160 of the close DLY tri-crossbreedings of age in days, parity, body weight, be divided into two groups at random, be respectively test group and control group.
3.2 feeding and management: test is carried out at open type growth house, and duration of test adopts the mode of feeding of free choice feeding, is unit note material with the hurdle, guarantees clean sufficient drinking-water.Various vaccine injections and epidemic prevention and control are all carried out and strict personal management according to a conventional method.Observe every day pig hair color, search for food, the activity situation, the test in advance the phase of raising be 7 days, 29 days formal test phases.
3.3 daily ration and trophic level (%)
Table 5 daily ration and trophic level (%)
| Grouping | Corn | Wheat | Dregs of beans | Wheat bran | The dish dregs of rice | Cotton dregs | Premix | It is upright strong to live |
| Control group | 46 | 20 | 14 | 10 | 3 | 3 | 4 | |
| Test group | 46 | 20 | 14 | 10 | 3 | 3 | 4 | 0.25 |
4. result of the test
4.1 result of the test
Table 6 result of the test
| Control group | Test group | |
| Number (head) | 80 | 80 |
| Beginning phase counterpoise (kg) | 23.08 | 24.04 |
| Finish counterpoise (kg) | 38.74 | 40.28 |
| Head is weightening finish (kg/ head) all | 15.66 | 16.24 |
| Average daily gain (kg/ head/day) | 0.54 | 0.56 |
| On average search for food heavily (the kg/ head/ | 1.28 | 1.22 |
| Day) | ||
| Efficiency of feed utilization | 2.37 | 2.18 |
| The incidence of disease (%) | 6.25 | 1.25 |
As seen from the above table, the control group daily gain is 540 grams, and test group is 560 grams, and test group has improved 3.7% than control group; The control group efficiency of feed utilization is 2.37: 1, and test group is 2.18: 1, and test group has improved 8.0% than control group; The average daily ingestion amount of control group is 1.28 kilograms, and test group is 1.22 kilograms, and test group has improved 4.7% than control group; The incidence of disease of test group is 1.25%, and control group is 6.25%, and test group has reduced by 5 percentage points than control group.
4.2 Economic and Efficiency Analysis
Table 7 Economic and Efficiency Analysis
| Group | Feed unit price (unit/kilogram) | Efficiency of feed utilization | Cost per gain weight (unit/kilogram) |
| Control group | 1.78 | 2.37 | 4.22 |
| Test group | 1.83 | 2.18 | 3.99 |
As seen from the above table, the test group cost per gain weight is lower 0.23 yuan/kilogram than control group, has reduced by 5.5%, and economic benefit is very remarkable.
5. discuss and brief summary
Observe in the process of the test and find, a test group pig hair color light, skin be ruddy, quiet, do not fight, as seen strengthening material " it is upright strong to live " makes an addition in the piglet diet, can effectively improve premunition, feed intake and the daily gain of piglet, promote piglet growth, improve the economic benefit of raising pigs, this test shows that exploitation and the application of strengthening material have vast market prospect.
The application test of material in piglet diet strengthened in test seven
1, test objective: understand to strengthen and expect " it the is upright strong to live " growth promotion in the piglet growth process and the effect of increase feed intake.
2, test site: kind pig farm, Nanyang
3, test material and method
3.1 test pig only: selects 100 of 25 kilograms of left and right sides two-way cross piglets, size is even, and male and female half and half is divided into two groups at random, i.e. test group and control group, 50 every group, every group of two repetitions, test period 13 days.
3.2 feeding and management: the test pig duration of test adopts free choice feeding, freely drinks water, and weighs record test pig feed consumption when on-test and end in the morning on an empty stomach.
3.3 daily ration prescription
Table 8 daily ration prescription
| Raw material | Corn | Wheat | Dregs of beans | The dish dregs of rice | Wheat bran | Cotton dregs | Premix | It is upright strong to live |
| The test group proportioning | 480 | 160 | 180 | 20 | 100 | 20 | 40 | 0.25 |
| The control group proportioning | 480 | 160 | 180 | 20 | 100 | 20 | 40 |
4, test results and analysis
4.1 result of the test
Table 9 result of the test
| Test group | Control group | |
| Number (head) | 50 | 50 |
| Head is starting weight (kg) all | 25.30 | 26.80 |
| Head is end heavy (kg) all | 32.48 | 33.82 |
| Total augment weight (kg) | 358.88 | 351.04 |
| Head is daily gain (g) all | 552.12 | 540.06 |
| Head is daily ingestion amount (kg) all | 1.21 | 1.25 |
| Efficiency of feed utilization | 2.19 | 2.31 |
| The incidence of disease (%) | 0 | 6 |
As seen from the above table, the test group average daily gain is 552.12 grams, and the control group average daily gain is 540.06 grams, and test group has improved 2.23% than high 12.06 grams of control group average daily gain; The average daily ingestion amount of test group is 1210 grams, and control group is 1250 grams, and test group has improved 3.2% than high 40 grams of control group; The test group efficiency of feed utilization is 2.19: 1, and control group is 2.31: 1, and test group has improved 5.2% than control group; The test group incidence of disease is zero, and the control group incidence of disease is 6%.
4.2 Economic and Efficiency Analysis
Table 10 Economic and Efficiency Analysis
| Group | Feed unit price (unit/kilogram) | Efficiency of feed utilization | Cost per gain weight (unit/kilogram) |
| Control group | 1.84 | 2.31 | 4.25 |
| Test group | 1.89 | 2.19 | 4.14 |
As seen from the above table, the test group cost per gain weight is lower 0.11 yuan/kilogram than control group, has reduced by 2.6%, and economic benefit is very remarkable.
5. discuss and brief summary
Contained active material enters in the animal body and can stimulate hypothalamic neuropeptide, gastrin in the feed addictive of the present invention " it is upright strong to live ", and the endogenous stimulus animal increases appetite, improves feed intake, in addition, and by stimulating animal taste bud, exogenous increase animal appetite; The immunity that " it is upright strong to live " also can improve body reduces the generation of disease, promotes fast growth of animal.
Add feed addictive of the present invention " it is upright strong to live " in the little pig feed, can obviously improve every production performance of pig.Though its cost is high slightly, but the overall economic efficiency that it brings is very remarkable, is worth applying aborning.
Claims (2)
1. feed addictive, it is characterized in that, comprise following compositions in weight portion and be prepared from: Radix Astragali 3000-5000 part, betel nut 700-900 part, hawthorn 1500-3000 part, ferrous sulfate 1000-2000 part, sodium selenite 8-15 part, 50% vitamin E powder 800-1200 part, seasoning peptide 800-1500 part, flavour nucleotide disodium 200-400 part, pure vitamin C powder 1500-2500 part; Described seasoning peptide is by 5 '-Sodium guanylate (C
10H
12N
5Na
2O
8P), sweet taste peptide and that western peptide (C
51H
43N
13O
12S
6) mix by 1: 1: 2 proportioning; The preparation method of described feed addictive may further comprise the steps:
(1) Chinese herbal medicine lixiviate: after the impurity elimination respectively of Chinese herb astragalus, betel nut, hawthorn, pulverizing, mix, and feed steam and size mixing, when being warming up to 80-90 ℃, the active ingredient organic acid in the Chinese herbal medicine, amino acid lixiviate are come out;
(2) Chinese herbal medicine and inorganic iron selenium chelating: with Chinese herbal medicine leaching liquor, reduce the temperature to 45 ℃, add hydrochloric acid and regulate pH, add ferrous sulfate and sodium selenite again, chelatropic reaction 15-20 hour continuously to 4.0-5.5;
(3) fortification of Chinese herbal medicine iron selenium chelate: 5 '-Sodium guanylate, sweet taste peptide and that western peptide are joined in the Chinese herbal medicine iron selenium chelate by seasoning peptide, flavour nucleotide disodium and vitamin C and 50% vitamin E powder that 1: 1: 2 proportioning mixes, get final product finished product.
2. feed addictive according to claim 1 is characterized in that, described sweet taste peptide is 2-L-aspartyl-L-phenylalanine methyl esters (C
14H
18N
2O
3).
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| CN104222496A (en) * | 2014-08-08 | 2014-12-24 | 广州海因特生物技术有限公司 | Environment-friendly type feed additive capable of preventing skeletal muscle edema of Rana catesbeiana Shaw |
| CN105918663A (en) * | 2016-06-02 | 2016-09-07 | 安徽禹王养殖有限公司 | Special cattle weight-gaining feed |
| CN106172225A (en) * | 2016-07-29 | 2016-12-07 | 颜海 | A kind of method increasing pig grazing rate |
| CN109480107A (en) * | 2018-12-21 | 2019-03-19 | 广东驱动力生物科技股份有限公司 | A kind of feed supplementation and preparation method thereof can provide hematopoiesis nutrient meat |
| CN112544814B (en) * | 2020-11-27 | 2023-10-20 | 广西壮族自治区畜牧研究所 | Chicken feed based on plant metal ion chelating liquid and application thereof |
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| CN1101227A (en) * | 1993-10-04 | 1995-04-12 | 石家庄金盟企业集团 | Fodder additives |
| CN1358446A (en) * | 2000-12-18 | 2002-07-17 | 谭明兴 | Chinese medicinal herb fodder additive |
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| CN1489925A (en) * | 2002-10-15 | 2004-04-21 | 韩文朝 | Concentrated feed for rapidly fattening ruminant |
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