CN101129541B - Medicament for treating bone joint disease - Google Patents
Medicament for treating bone joint disease Download PDFInfo
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- CN101129541B CN101129541B CN2007100550853A CN200710055085A CN101129541B CN 101129541 B CN101129541 B CN 101129541B CN 2007100550853 A CN2007100550853 A CN 2007100550853A CN 200710055085 A CN200710055085 A CN 200710055085A CN 101129541 B CN101129541 B CN 101129541B
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Abstract
The invention discloses a medicament for treating waist and leg pains, wherein the oral administration dose form is prepared from the following raw materials (by weight portion): wild or spiny jujuba root 12-18 parts, fig root 12-18 parts, nodular branch of pine 12-20 parts, and the externally used dose form is prepared from the following raw materials (by weight ratio): purslane 370-430 parts, pumpkin vine 270-330 parts, fresh ginger 220-280 parts, Chinese mugwort leaf 270-330 parts, safflower 130-170 parts, ledebouriella root 370-430 parts. The externally used medicament can also comprise seabuckthorn fruit 450-550 parts, Indian mallow 270-330 parts, mulberry twig 450-550 parts, willow branch 450-550 parts, pine 450-550 part.
Description
Technical field:
The present invention relates to medicine, further is the Chinese medicine that is used for the treatment of joint diseases such as rheumatoid, osteonecrosis of femoral head, ankylosing spondylitis.
Background technology:
Osteoarthritis such as rheumatoid disease, osteonecrosis of femoral head, ankylosing spondylitis belong to difficult and complicated illness, and Chang Fanfu outbreak, touching difficulty are more having a strong impact on human beings'health.The many Western medicine that are used for the treatment of joint disease at present, the method for employing anti-inflammatory analgesic can only be taken stopgap measures and can not effect a permanent cure, and be formed drug dependence easily, leads to complications, and causes the infringement of renal function.The method and the medicine of many treatments by Chinese herbs are also arranged on the market, certain pluses and minuses are respectively arranged, still do not have specific medicament.
Summary of the invention:
The purpose of this invention is to provide and a kind ofly make simple, easy to use, effect and treat medicine of joint disease and preparation method thereof preferably.
The objective of the invention is to realize: a kind of medicine for the treatment of joint disease by following scheme, it is characterized in that: be made up of with external two parts for oral administration, a, part for oral administration are made by the following weight proportion raw material: 12～18 parts of Radix ziziphi mauritianae, 12～18 parts of Radix Fici, 12～20 parts of Lignum Pini Nodis; B, external part are made by the following weight proportion raw material: 370～430 parts of Herba Portulacaes, 270～330 parts of Caulis Cucurbitaes, 220～280 parts in Rhizoma Zingiberis Recens, 270～330 parts of Folium Artemisiae Argyis, 130～170 parts on Flos Carthami, 370～430 parts of Radix Saposhnikoviaes.
Also can add 450～550 parts of Fructus Hippophaes in the medicine for external use of the present invention, 270～330 parts of Herba Abutilis; 450～550 parts of Ramulus Moris, 450～550 parts of Ramulus Salicis Babylonicaes, 450～550 parts in Masson Pine; And 900～1100 parts of SHAJIANGSHI.
Preferable range is: a, part for oral administration: made by the following weight proportion raw material: 13～17 parts of Radix ziziphi mauritianae, 13～17 parts of Radix Fici, 14～18 parts of Lignum Pini Nodis; B, external part: make: 390～410 parts of Herba Portulacaes, 290～310 parts of Caulis Cucurbitaes, 240～260 parts in Rhizoma Zingiberis Recens, 290～310 parts of Folium Artemisiae Argyis, 140～160 parts on Flos Carthami, 390～410 parts of Radix Saposhnikoviaes by the following weight proportion raw material.
Also can add 480～520 parts of Fructus Hippophaes in the medicine for external use of the present invention, 290～310 parts of Herba Abutilis; 480～520 parts of Ramulus Moris, 480～520 parts of Ramulus Salicis Babylonicaes, 480～520 parts in Masson Pine; And 950～1050 parts of SHAJIANGSHI.
Preferred plan is: a, part for oral administration: made by the following weight proportion raw material: 15 parts of Radix ziziphi mauritianae, 15 parts of Radix Fici, 16 parts of Lignum Pini Nodis; B, external part: make: 400 parts of Herba Portulacaes, 300 parts of Caulis Cucurbitaes, 250 parts in Rhizoma Zingiberis Recens, 300 parts of Folium Artemisiae Argyis, 150 parts on Flos Carthami, 400 parts of Radix Saposhnikoviaes by the following weight proportion raw material.
Also can add 500 parts of Fructus Hippophaes in the medicine for external use of the present invention, 300 parts of Herba Abutilis; 500 parts of Ramulus Moris, 500 parts of Ramulus Salicis Babylonicaes, 500 parts in Masson Pine; And 1000 parts of SHAJIANGSHI.
When oral medicine is made, above-mentioned medical material for oral administration is added the water of 20～30 times of medical material weight, decoct, when boiling when water remains 2/3 left and right sides, filtering residue is standby; When application compress are made, the medical material of above-mentioned external is added the water of 4～6 times of medical material weight together, decoct, when water remained 2/3 left and right sides, filtering residue was standby.
During use: oral medicine every day twice, sooner or later each once, each 250 milliliters; Medicine for external use carries out hot compress to lesions position and emphasis acupuncture point, cooperates cup afterwards 10～15 minutes.
Among the present invention: Radix ziziphi mauritianae has nourishing heart, calms the nerves, the effect of arresting sweating; Radix Fici has relaxing muscles and tendons and activating QI and blood in the collateral, dispersing swelling and dissipating binds, the effect of hot lactogenesis disappears; Lignum Pini Nodi has the effect of dispeiling pathogenic wind and removing dampness, channels sootheing and network vessel quickening, pain relieving; Fructus Hippophae has promoting blood circulation to remove blood stasis, the chest stuffiness relieving reduces phlegm, spleen reinforcing is good for the stomach effect; Herba Abutili has the effect of clearing away heat-damp and promoting diuresis, detoxifcation treatment nebula; Effects such as Herba Portulacae has clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, the diuresis of quenching the thirst, parasite killing is treating stranguria; Caulis Cucurbitae has the effect of antiinflammatory, analgesia, blood stasis dispelling; The effect that Rhizoma Zingiberis Recens has warming spleen and stomach for dispelling cold, recuperating depleted YANG and rescuing the patient from collapse, induces sweat and disperse; Folium Artemisiae Argyi has the effect of dispersing cold for relieving pain, warming the meridian for stopping bleeding; Flos Carthami has the effect of blood circulation promoting and blood stasis dispelling, removing pathogenic heat from blood and toxic substance from the body, resolving stagnation for tranquilization; The effect that Radix Saposhnikoviae has expelling wind and dampness, induces sweat and disperse; Ramulus Mori has the effect of wind-damp dispelling, the meridian dredging, row aqueous vapor; Ramulus Salicis Babylonicae have dispel the wind, the effect of detumescence, analgesic, analgesia; Masson Pine have invigorate blood circulation, the effect of pain relieving.
Take innerwear outer treatment " numbness of dispelling the is good for the bone spirit " soup of making of the present invention, adopt the method for hot compress guiding, acupuncture point cup, internal and external application, can be used for treating various osteoarthritis, as rheumatoid, osteonecrosis of femoral head, ankylosing spondylitis etc., effect with heat-clearing and toxic substances removing, expelling wind and cold, relaxing muscles and tendons and activating QI and blood in the collateral, nourishing vim and vigour, can produce following beneficial effect: 1, numbness relieving and pain relieving is effective, specially good effect is arranged, the cure rate height to repairing osteoarthrosis.Show total effective rate 100% through 36 routine clinical trials.2, raw material is easy to get, and processing technology is simple; 3, use pure Chinese medicine preparation, have no side effect; 4, cost is lower, is easily accepted by the patient.
The specific embodiment:
Testing data:
1, cures mainly
Be used for the treatment of various joint disease such as rheumatoid, osteonecrosis of femoral head, ankylosing spondylitis.
2, treatment 36 examples, male's 21 examples wherein, women's 15 examples; Age distribution is: 10 examples below 20 years old, 21～30 years old 8 example, 31～40 years old 8 example, 41～50 years old 6 example, 4 examples more than 50 years old; Maximum 65 years old age, minimal ages 7 years old, 38 years old mean age.Course of disease elder 6 years, weak point person June, average course of disease 2.1 years.
3, Therapeutic Method
During use: oral medicine every day twice, sooner or later each once, each 250 milliliters; Medicine for external use carries out hot compress to lesions position and emphasis acupuncture point, cooperates cup afterwards 10～15 minutes.
4, contraindication
During the treatment, avoid having sexual intercourse, drinking.
5, efficacy assessment standard
Produce effects: pain disappears, and diet is normal, and freedom of movement is taken care of oneself, and observes 3 months no recidivists;
Take a turn for the better: pain disappears substantially, and diet is normal substantially, and activity is obviously convenient;
Invalid: as not reach improvement target person.
6, therapeutic effect
86 days courses of treatment of mean treatment, 190 days the longest courses of treatment, 30 days the shortest courses of treatment, medication produce effects 29 examples, obvious effective rate 80.5%; 7 examples that take a turn for the better, improvement rate 19.5%; Total effective rate 100%.Invalid 0 example.
Model case is introduced:
1, high * *, the woman, 7 years old, river, Shandong, Puyang County, Henan Province village people violated rheumatoid disease 2 years, 5,60,000 yuan of large hospital costs, did not heal; When examine in March, 2006, worn to a shadow, almost be in shock state, treated 100 days, but post to turn walking, the 5-6 month is supported in the back, takes care of oneself.
2, bent * *, the man, 26 years old, area just outside a city gate people from town, Xiajin County, Shandong Province suffered from rheumatoid more than 4 years, joint swelling and pain be can't take care of oneself.Examine in April, 2007, and through treatment, after 1 course of treatment, pain disappears, and takes care of oneself.
3, Lee * *, the man, 54 years old, the beam village, Puyang County, Henan Province village people suffered from osteonecrosis of femoral head 2 years, whole body pain is felt bad, after 1 course of treatment of medication, transference cure, freedom of movement.
4, Lee * *, the woman, 56 years old, Shandong Province's Dongying people from city, osteonecrosis of femoral head was suffered from more than 2 years in both sides, the diagnosis and treatment of coming in July, 2002, after medication 3 courses of treatment, transference cure, freedom of movement.
5, Guo * *, the man, 32 years old, Puyang County, Henan Province people from county town suffered from ankylosing spondylitis more than 2 years, deformation of spinal column bends to humpback, walking disorder spends more than 50,000 yuan in how tame hospital, has no resolution, the diagnosis and treatment of coming in February, 2006, low back became straight in 1 month, it is normal substantially to walk.
6, Cui * *, the man, 65 years old, the hot shop village people in Shandong Province's Dongying city suffered from ankylosing spondylitis more than 2 years, the deformation of spinal column distortion, difficulty in walking, the diagnosis and treatment of coming in November, 2002, through 2 wheat harvesting periods, waist directly recovers normally, walks freely.
Below in conjunction with embodiment the present invention is done further narration:
Embodiment 1: a kind of medicine for the treatment of joint disease, form a, part for oral administration: make by the following weight proportion raw material: 12 parts of Radix ziziphi mauritianae, 12 parts of Radix Fici, 12 parts of Lignum Pini Nodis with external two parts by for oral administration; B, external part: make: 370 parts of Herba Portulacaes, 270 parts of Caulis Cucurbitaes, 220 parts in Rhizoma Zingiberis Recens, 270 parts of Folium Artemisiae Argyis, 130 parts on Flos Carthami, 370 parts of Radix Saposhnikoviaes by the following weight proportion raw material.
Also can add 450 parts of Fructus Hippophaes in the medicine for external use of the present invention, 270 parts of Herba Abutilis, 450 parts of Ramulus Moris, 450 parts of Ramulus Salicis Babylonicaes, 900 parts of 450 parts in Masson Pine and SHAJIANGSHI simply or multi-flavor.
When oral medicine is made, above-mentioned medical material for oral administration is added the water of 20～30 times of medical material weight, decoct, when boiling when water remains 2/3 left and right sides, filtering residue is standby; When application compress are made, above-mentioned external medical material is added the water of 4～6 times of medical material weight together, decoct, when water remained 2/3 left and right sides, filtering residue was standby.
Using method is with reference to above-mentioned, down together.
Embodiment 2: a kind of medicine for the treatment of joint disease, form a, part for oral administration: make by the following weight proportion raw material: 18 parts of Radix ziziphi mauritianae, 18 parts of Radix Fici, 20 parts of Lignum Pini Nodis with external two parts by for oral administration; B, external part: make: 430 parts of Herba Portulacaes, 330 parts of Caulis Cucurbitaes, 280 parts in Rhizoma Zingiberis Recens, 330 parts of Folium Artemisiae Argyis, 170 parts on Flos Carthami, 430 parts of Radix Saposhnikoviaes by the following weight proportion raw material.
Also can add 550 parts of Fructus Hippophaes in the medicine for external use of the present invention, 330 parts of Herba Abutilis, 550 parts of Ramulus Moris, 550 parts of Ramulus Salicis Babylonicaes, 1100 parts of 550 parts in Masson Pine and SHAJIANGSHI simply or multi-flavor.
Manufacture method is with embodiment 1.
Embodiment 3: a kind of medicine for the treatment of joint disease, form a, part for oral administration: make by the following weight proportion raw material: 13 parts of Radix ziziphi mauritianae, 13 parts of Radix Fici, 14 parts of Lignum Pini Nodis with external two parts by for oral administration; B, external part: make: 390 parts of Herba Portulacaes, 290 parts of Caulis Cucurbitaes, 240 parts in Rhizoma Zingiberis Recens, 290 parts of Folium Artemisiae Argyis, 140 parts on Flos Carthami, 390 parts of Radix Saposhnikoviaes by the following weight proportion raw material.
Also can add 480 parts of Fructus Hippophaes in the medicine for external use of the present invention, 290 parts of Herba Abutilis, 480 parts of Ramulus Moris, 480 parts of Ramulus Salicis Babylonicaes, 950 parts of 480 parts in Masson Pine and SHAJIANGSHI simply or multi-flavor.
Manufacture method is with embodiment 1.
Embodiment 4: a kind of medicine for the treatment of joint disease, form a, part for oral administration: make by the following weight proportion raw material: 17 parts of Radix ziziphi mauritianae, 17 parts of Radix Fici, 18 parts of Lignum Pini Nodis with external two parts by for oral administration; B, external part: make: 410 parts of Herba Portulacaes, 310 parts of Caulis Cucurbitaes, 260 parts in Rhizoma Zingiberis Recens, 310 parts of Folium Artemisiae Argyis, 160 parts on Flos Carthami, 410 parts of Radix Saposhnikoviaes by the following weight proportion raw material.
Also can add 520 parts of Fructus Hippophaes in the medicine for external use of the present invention, 310 parts of Herba Abutilis, 520 parts of Ramulus Moris, 520 parts of Ramulus Salicis Babylonicaes, 1050 parts of 520 parts in Masson Pine and SHAJIANGSHI simply or multi-flavor.
Manufacture method is with embodiment 1.
Embodiment 5: a kind of medicine for the treatment of joint disease, form a, part for oral administration: make by the following weight proportion raw material: 15 parts of Radix ziziphi mauritianae, 15 parts of Radix Fici, 16 parts of Lignum Pini Nodis with external two parts by for oral administration; B, external part: make: 400 parts of Herba Portulacaes, 300 parts of Caulis Cucurbitaes, 250 parts in Rhizoma Zingiberis Recens, 300 parts of Folium Artemisiae Argyis, 150 parts on Flos Carthami, 400 parts of Radix Saposhnikoviaes by the following weight proportion raw material.
Also can add 500 parts of Fructus Hippophaes in the medicine for external use of the present invention, 300 parts of Herba Abutilis, 500 parts of Ramulus Moris, 500 parts of Ramulus Salicis Babylonicaes, 1000 parts of 500 parts in Masson Pine and SHAJIANGSHI simply or multi-flavor.
Manufacture method is with embodiment 1.
In the various embodiments of the present invention, described Radix ziziphi mauritianae refers to the root of Zizyphus jujuba (ujuba var.spinosa(Bunge)Hu); Radix Fici is the root of Ficus carica L., and also available SHANCAOGEN substitutes; Caulis Cucurbitae can replace with Folium Cucurbitae; Folium Artemisiae Argyi can replace with Folium Artemisiae Argyi; Ramulus Mori refers to the branch of mulberry, and also available Folium Mori substitute; Ramulus Salicis Babylonicae refers to the branch of willow, and also available Folium Salicis Babylonicae substitutes; Masson Pine refers to the wood of Pinus tabuliformis or Pinus massoniana Lamb; SHAJIANGSHI refers to a plurality of irregular eyelets are arranged, to be khaki stone (as all collecting) in the river sand on ground such as Henan Province's Puyang, Shandong Dongying City mixing in river sand.In the embodiment of the invention, also can increase other relevant composition.
Claims (9)
1. medicine for the treatment of joint disease is characterized in that: is made up of with external two parts for oral administration, a, takes part orally, made by the following weight proportion raw material: 12～18 parts of Radix ziziphi mauritianae, 12～18 parts of Radix Fici, 12～20 parts of Lignum Pini Nodis; B, external part comprise by the following weight proportion raw material and making: 370～430 parts of Herba Portulacaes, 270～330 parts of Caulis Cucurbitaes, 220～280 parts in Rhizoma Zingiberis Recens, 270～330 parts of Folium Artemisiae Argyis, 130～170 parts on Flos Carthami, 370～430 parts of Radix Saposhnikoviaes.
2. a kind of medicine for the treatment of joint disease according to claim 1, it is characterized in that: the external of this medicine partly adds 450～550 parts of Fructus Hippophaes, 270～330 parts of Herba Abutilis, 450～550 parts of Ramulus Moris, 450～550 parts of Ramulus Salicis Babylonicaes, 900～1100 parts of 450～550 parts in Masson Pine and SHAJIANGSHI simply or multi-flavor.
3. a kind of medicine for the treatment of joint disease according to claim 1 is characterized in that: the external of this medicine partly adds 450～550 parts of Fructus Hippophaes, 270～330 parts of Herba Abutilis.
4. a kind of medicine for the treatment of joint disease according to claim 1 is characterized in that: the external of this medicine partly adds 450～550 parts of Ramulus Moris, 450～550 parts of Ramulus Salicis Babylonicaes, 900～1100 parts of 450～550 parts in Masson Pine and SHAJIANGSHI.
5. a kind of medicine for the treatment of joint disease according to claim 1 is characterized in that: a, part for oral administration, make by the following weight proportion raw material: 15 parts of Radix ziziphi mauritianae, 15 parts of Radix Fici, 16 parts of Lignum Pini Nodis; B, external part comprise by the following weight proportion raw material and making: 400 parts of Herba Portulacaes, 300 parts of Caulis Cucurbitaes, 250 parts in Rhizoma Zingiberis Recens, 300 parts of Folium Artemisiae Argyis, 150 parts on Flos Carthami, 400 parts of Radix Saposhnikoviaes.
6. a kind of medicine for the treatment of joint disease according to claim 5 is characterized in that: the external of this medicine partly adds 500 parts of Fructus Hippophaes, 300 parts of Herba Abutilis, 500 parts of Ramulus Moris, 500 parts of Ramulus Salicis Babylonicaes, 500 parts in Masson Pine, 1000 parts of SHAJIANGSHI simply or multi-flavor.
7. a kind of medicine for the treatment of joint disease according to claim 5 is characterized in that: the external of this medicine partly adds 500 parts of Fructus Hippophaes, 300 parts of Herba Abutilis.
8. a kind of medicine for the treatment of joint disease according to claim 5 is characterized in that: the external of this medicine partly adds 500 parts of Fructus Hippophaes, 300 parts of Herba Abutilis, 500 parts of Ramulus Moris, 500 parts of Ramulus Salicis Babylonicaes, 500 parts in Masson Pine, 1000 parts of SHAJIANGSHI.
9. a kind of according to claim 1 or 5 manufacture method for the treatment of the medicine of joint disease, it is characterized in that: when part for oral administration was made, the water with 20～30 times of above-mentioned medical material adding medical material weight for oral administration decocted, when boiling when water remains 2/3 left and right sides, filtering residue is standby; When external is partly made, above-mentioned external medical material is added the water of 4～6 times of medical material weight together, decoct, when water remained 2/3 left and right sides, filtering residue was standby.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007100550853A CN101129541B (en) | 2007-08-30 | 2007-08-30 | Medicament for treating bone joint disease |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007100550853A CN101129541B (en) | 2007-08-30 | 2007-08-30 | Medicament for treating bone joint disease |
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| Publication Number | Publication Date |
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| CN101129541A CN101129541A (en) | 2008-02-27 |
| CN101129541B true CN101129541B (en) | 2011-04-20 |
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| CN2007100550853A Expired - Fee Related CN101129541B (en) | 2007-08-30 | 2007-08-30 | Medicament for treating bone joint disease |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1686499A (en) * | 2005-03-21 | 2005-10-26 | 朱春营 | Articular pain relieving pill |
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- 2007-08-30 CN CN2007100550853A patent/CN101129541B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1686499A (en) * | 2005-03-21 | 2005-10-26 | 朱春营 | Articular pain relieving pill |
Non-Patent Citations (2)
| Title |
|---|
| 闵文等.中医辨证内治骨关节炎的研究.中国中医骨伤科杂志11 2.2003,11(2),61-63. |
| 闵文等.中医辨证内治骨关节炎的研究.中国中医骨伤科杂志11 2.2003,11(2),61-63. * |
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