CN101119698A - Medical needles having antibacterial and painless function - Google Patents
Medical needles having antibacterial and painless function Download PDFInfo
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- CN101119698A CN101119698A CNA2006800052207A CN200680005220A CN101119698A CN 101119698 A CN101119698 A CN 101119698A CN A2006800052207 A CNA2006800052207 A CN A2006800052207A CN 200680005220 A CN200680005220 A CN 200680005220A CN 101119698 A CN101119698 A CN 101119698A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
- A61M5/422—Desensitising skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/329—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle shaft
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- Dermatology (AREA)
- Finger-Pressure Massage (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The present invention relates to medical needles having antibacterial and painless functions, and more particularly, to medical needles having excellent antibacterial activity, and at the same time, a function of relieving the pain of patients, in which silver (Ag) particles having a diameter of nanometers are contained in the needle body or coated on the needle surface. The inventive medical needles include a needle for injection, a needle for operation, and a needle for acupuncture.
Description
Technical field
The present invention relates to a kind of antibiotic and medical needle painless function of having, particularly, relate to and have the medical needle that outstanding antibacterial functions can alleviate patient's pain simultaneously, this needle body contain or wire surface on scribble silver (Ag) particle with nanometer diameter.Medical needle of the present invention comprises pumping needle, surgical needles and acupuncture needle.
Background technology
Usually, for example pumping needle, surgical needles or acupuncture needle are applied to patient by staff to medical needle.Yet well-known is that the antibacterial that exists on the staff has 200000-300000ea/cm
2Or it is more.And if wash one's hands or sterilize inadequate words, detected number of bacteria may further increase, and more serious situation is, also has microorganism and mould on hand.Therefore, when the operator operated medical needle, patient might be by bacterial infection in this program.
Recently, the nanometer silver technology of making the particle with millimicro meter level is used to various industrial circles.As everyone knows, Nano silver grain is processed with sol solution or particulate form, harmless and have antibiotic, deodorize, anti-ultraviolet and anti-function solenoid etc.
In antibacterial mechanisms, the cell membrane of Nano silver grain dissolving noxious bacteria also influences intracellular enzyme to forbid the metabolic function of nutrient substance, that is to say, introduces and the release nutrient substance, kills deleterious antibacterial at last.The size of Nano silver grain is more little, and its sterilization and antimicrobial function are just good more, and Nano silver grain has shown strong antibiotic and sterilizing function.These antibacterials have: big enterobacteria, staphylococcus, Mycobacterium, vibrio, Shigella, pneumonia, salmonella typhi and methicillin staphylococcus aureus.
Summary of the invention
An object of the present invention is to provide a kind of antibiotic and medical needle painless function of having, this needle body contain or wire surface on scribble Nano silver grain.This medical needle can be avoided simultaneously, alleviating patient's pain by the caused risk of bacterial infections of operator's hands.
Description of drawings
Shown in Figure 1 is various types of acupuncture needles;
Shown in Figure 2 is the perspective view of conventional syringe;
Fig. 3 is that the cross section of the medical needle of making according to the present invention amplifies the photo after 60,000 times under ultramicroscope;
Fig. 4 is that side according to medical needle of the present invention is at the photo that amplifies under the ultramicroscope after 80,000 times;
Fig. 5 is a sketch map of making electrical acupuncture for adiposis patient.
The specific embodiment
One embodiment of the present of invention provide a kind of medical needle that is selected from pumping needle, surgical needles and the acupuncture needle, and wherein, the diameter that scribbles the 0.01-50 micron thickness on this wire surface is the Nano silver grain of 0.1-300 nanometer.
An alternative embodiment of the invention provides a kind of medical needle that is selected from pumping needle, surgical needles and the acupuncture needle, and wherein, it is that the diameter of the 0.01-20% of pin weight is the Nano silver grain of 0.1-300 nanometer that this needle body contains weight.
Below, more detailed description the present invention.
One embodiment of the present of invention provide a kind of medical needle that is selected from pumping needle, surgical needles and the acupuncture needle, and wherein, the diameter that scribbles the 0.01-50 micron thickness on this wire surface is the Nano silver grain of 0.1-300 nanometer.If the coating layer thickness of Nano silver grain is less than 0.01 micron, the Nano silver grain that is coated with will show a bit even not have an effect, and if the coating layer thickness of Nano silver grain greater than 50 microns, will cause cost to increase, and the increase of coating layer thickness does not impact.
Nano silver grain used in the present invention has the particle diameter of 0.1-300 nanometer.This is because can't be implemented in present technology less than the particle of 0.1 nanometer, and reduce greater than the antibacterial effect of the particle of 300 nanometers.
An alternative embodiment of the invention provides a kind of medical needle, and wherein, this needle body contains the Nano silver grain that weight is the 0.01-20% of pin weight.If the weight ratio of the Nano silver grain that needle body contains is less than 0.01%, antimicrobial effect is very little or do not have; If the weight ratio of the Nano silver grain that needle body contains is greater than 20%, then the intensity of pin reduces, and the viscosity of pin increases, and has increased pin and has inserted the difficulty of human body, and increased production cost.
Shown in Figure 1 is various types of acupuncture needles according to first embodiment of the invention.As shown in Figure 1, each acupuncture needle 20 comprises: pin portion 22 and handle portion 24.According to the present invention, Nano silver grain is comprised in the pin portion 22 or is coated in pin portion 22.
Shown in Figure 2 is the perspective view of conventional syringe.As shown in Figure 2, described syringe comprises pumping needle 30 and syringe 35, and wherein pumping needle 30 is made up of pin portion 32 and connecting portion 34.Pin portion 32 is made of metal usually, and connecting portion 34 and syringe 35 are made by synthetic resin.According to the present invention, pin portion 32 comprises Nano silver grain or scribbles Nano silver grain at least.In order to increase effect of the present invention, except pin portion 32, connecting portion 34 and syringe 35 also can comprise Nano silver grain or scribble Nano silver grain.
Fig. 3 be the pin made according to the plasma coating method cross section amplify under the ultramicroscope after 60,000 times photo.As shown in Figure 3, the cross section that is coated in the Nano silver grain coating on the needle body is very smooth, and the expression Nano silver grain is used as lubricant.
Fig. 4 is that side according to the pin that scribbles Nano silver grain of the present invention is at the photo that amplifies under the ultramicroscope after 80,000 times.
The medical needle that contains Nano silver grain according to the present invention can be by following method manufacturing.The metal material of formation pin portion is heated and melts, and is added in Nano silver grain in the melt and stirring, then, and the molded or injection the mixture that stirs.Molded or injected material is slowly cooled off, and has therefore made medical needle of the present invention.
According to one embodiment of present invention, scribbling the medical needle of Nano silver grain can be by the electric plating method manufacturing.At first needle body is through washing and cleaning to remove top impurity.Needle body after the cleaning washes with water then with the linen polishing, then, and passing to unidirectional current again in the needle body immersion plating liquid.Then, pin is put into electroplating bath, then through basic plating and nickel plating step.Pin after the plating immerses in the silver nano-particle solution, and then passes through unidirectional current.Then, the pin process is cleaned and drying steps, thereby has made the medical needle that is coated with Nano silver grain.
In addition, according to another embodiment of the present invention, the medical needle that scribbles Nano silver grain can be made by plasma coating method.Pin is placed in the drying machine dry to evaporate moisture shown in reference number through washing and clean removing the impurity on surface then.Then, pin is contained in the support, puts into the plasma vacuum chamber, and gas is introduced this vacuum chamber.Then, pin process plasma ion disinfection, surface treatment for the first time and surface treatment for the second time.Then, coated with silver nano-particles is dry then on pin, has therefore made the medical needle that scribbles Nano silver grain.
Below, by following Example and test case the effect that possesses the medical needle of antibiotic and painless function of the present invention is described.
Example
On market, buy 5000 stainless pumping needles (226 quantifier), 5000 electric needles (long 10.5cm), 5000 spring pins (long 6cm).These crowns are according to being coated with Nano silver grain under the plasma coating method condition below.
1) coating place: S. university plasma center
2) depositing device: the wide * length * height of settling chamber is 850 * 850 * 700, target size: 375 * 120,
Target 1 part 2EA (sum: 6EA), magnet 1 part 2EA (sum: 6EA),
Direct current or radio-frequency power, 7000 liters/minute of MBP+ screw pumps, turbomolecular pump 3000M3/H
3) support: rotary support
4) basic pressure: less than 10
-5Torr
5) used gas: argon (99.99%), oxygen (99.999%)
6) tonnage (argon pressure): 1-10mtorr
7) gas flow: 9-100cc/min
8) temperature: room temperature
9) power: 10-150 watt
10) Yin index: 99.99% silver medal
11) want the article of coating: three kinds of stainless pins
12) indoor temperature: 100 degrees centigrade
13) the coating time: 60 minutes
Under these conditions, deposition power drops to 120W, and the surface at pin when changing deposition power forms the Nano silver grain coating.Measure the Nano silver grain coating, in order to change resistivity and adhesion property along with the variation of deposition pressure.Measurement result shows that coating has minimum resistivity 5.014 μ Ω cm when deposition pressure is 10m torr, and during greater than 5.014 μ Ω cm, resistivity increases at deposition pressure.Simultaneously, the formed film of the nano silver particles that on pin, is coated with in this example, smooth surface and even.
Test case 1: the test of electric conductivity
With the electric needles that scribbles Nano silver grain adiposis patient is carried out electrical acupuncture to reduce fat in this example.The electronic stimulator of using in the electrical acupuncture is the STAETRON (trade name) that has bought from the D medical company.Implement electrical acupuncture as shown in Figure 5.That is, electric needles 10 penetrates patient 100 fat sites with the alternate 3-5cm of straight line.Then, electric needles 10 and electronic stimulator 50 are electrically connected by electric wire 70, about 1 hour of 50 couples of patients of electronic stimulator, 100 effects.
Simultaneously, also be not coated with traditional rustless steel electric needles of Nano silver grain, penetrate same patient other position and with the operation of the same method of said method so that relatively patient's reaction.Result relatively is as shown in the table.
Table 1
| Clinical volunteer | The use of traditional electric needles | Scribble the use of the electric needles of Nano silver grain | Output current | Frequency | Time (minute) | |
| A:16 year male | Prick 8 pins in the abdominal part left side; Reactionless (when 35mA, reacting) | Prick 8 pins on the abdominal part right side; When 25mA, react | 10-35 mA | 50Hz | 20 | |
| B:18 year women | Prick 8 pins on the back right side; Reactionless (when 35mA, reacting) | Prick 8 pins at back; When 20mA, react | 10-35 | 40Hz | 30 |
| C:24 year male | Prick 6 pins in the left side of thigh inside; Reactionless (when 45mA, reacting) | Prick 6 pins on the right side of thigh inside; When 35mA, react | 10-45 mA | 70Hz | 30 | |
| D:26 year women | Prick 8 pins on the abdominal part right side; Reactionless (when 55mA, reacting) | Prick 8 pins in the abdominal part left side; When 35mA, react | 10-50 mA | 70Hz | 30 | |
| E:30 year male | Prick 8 pins in the abdominal part left side; Reactionless (when 65mA, reacting) | Prick 8 pins on the abdominal part right side; Reactionless; When 35mA, react | 10-60 mA | 70Hz | 30 | |
| F:35 year women | Prick 8 pins in the back left side; Reactionless (when 45mA, reacting) | Prick 8 pins on the back right side; When 30mA, react | 10-45 mA | 60Hz | 30 | |
| G:42 year male | Prick 6 pins on the right side of thigh inside; Reactionless (when 55mA, reacting) | Prick 6 pins in the left side of thigh inside; When 40mA, react | 10-55 mA | 80Hz | 30 | |
| H:44 year women | Prick 8 pins on the abdominal part right side; Reactionless (when 45mA, reacting) | Prick 8 pins in the abdominal part left side; When 35mA, react | 10-45 mA | 70Hz | 30 | |
| I:53 year male | Prick 8 pins in the abdominal part left side; Reactionless (when 55mA, reacting) | Prick 8 pins on the abdominal part right side; When 45mA, react | 10-60 mA | 90Hz | 30 | |
| J:55 year women | Prick 8 pins on the abdominal part right side; Reactionless (when 55mA, reacting) | Prick 8 pins on the abdominal part right side; When 45mA, react | 10-55 | 80Hz | 30 |
From the result of table 1 as can be seen, scribble in the present invention under the situation of electric needles of Nano silver grain, patient's reaction is than fast under the situation of traditional stainless electric needles, because the electric conductivity of electric needles of the present invention is than the electric conductivity height of conditional electronic pin.Simultaneously, women's reaction is sensitiveer than the male.In addition, because along with the intravital moisture of age people reduces, the electric conductivity of human body also reduces.
Test case 2: pain test (1)
The pinprick of 10 centimeter length is gone into 10 adiposis patients (5 male 5 woman's) fat sites 10, patient is applied electric current by electronic stimulator.Patient has compared sensation of pricking with the pin that scribbles Nano silver grain of the present invention and the sensation of pricking with previous stainless pin, and conclusion is shown in following table 2.
Table 2
| Clinical volunteer | The position of pricking with previous stainless pin | The position that the pin that scribbles Nano silver grain of the present invention is pricked | The sensation of pin of the present invention | The sensation of previous pin |
| A:16 year male | Prick 8 pins in the abdominal part left side | Prick 8 pins on the abdominal part right side | Very comfortable | Scorching hot |
| B:18 year women | Prick 8 pins on the back right side | Prick 8 pins at back | Comfortable | Coarse |
| C:24 year male | Prick 6 pins in the left side of thigh inside | Prick 6 pins on the right side of thigh inside | Comfortable, sleepy is felt | Pain |
| D:26 year women | Prick 8 pins on the abdominal part right side | Prick 8 pins in the abdominal part left side | Comfortable | Pain |
| E:30 year male | Prick 8 pins in the abdominal part left side | Prick 8 pins on the abdominal part right side | As snug as a bug in a rug | Pain |
| F:35 year women | Prick 8 pins in the back left side | Prick 8 pins on the back right side; | No pain | Pain |
| G:42 year male | Prick 6 pins on the right side of thigh inside | Prick 6 pins in the left side of thigh inside | Comfortable | Pain |
| H:44 year women | Prick 8 pins on the abdominal part right side | Prick 8 pins in the abdominal part left side | Sleepy is felt | Heavy |
| I:53 year male | Prick 8 pins in the abdominal part left side | Prick 8 pins on the abdominal part right side | As snug as a bug in a rug | Scorching hot |
| J:55 year women | Prick 8 pins on the abdominal part right side | Prick 8 pins in the abdominal part left side | Do not feel | Pain |
From the result of table 2 as can be seen, most patient is answered with previous stainless pin a coarse and searing pain, and the pin that scribbles Nano silver grain of the present invention is not almost not have pain but feel as snug as a bug in a rug.
Test case 3: pain test (2)
For pain and the sensation that when pinprick is gone into and extract, is produced, check patient tested in test case 2, the result is shown in following table 3.
Table 3
| Clinical volunteer | Previous stainless pin | The pin that scribbles Nano silver grain of the present invention | The effect of pin of the present invention | The effect of previous pin |
| A:16 year male | Prick 8 pins in the abdominal part left side | Prick 8 pins on the abdominal part right side | Not reaction | Pain, swelling |
| B:18 year women | Prick 8 pins on the back right side | Prick 8 pins at back | Insignificant pain | Hypersensitive, swelling, pain, pruritus |
| C:24 year male | Prick 6 pins in the left side of thigh inside | Prick 6 pins on the right side of thigh inside | Not reaction | Pain, swelling, pruritus |
| D:26 year women | Prick 8 pins on the abdominal part right side | Prick 8 pins in the abdominal part left side | Insignificant pain | Pain, allergy |
| E:30 year male | Prick 8 pins in the abdominal part left side | Prick 8 pins on the abdominal part right side | Not reaction | Pain, swelling, pruritus |
| F:35 year women | Prick 8 pins in the back left side | Prick 8 pins on the back right side; | Not reaction | Pain, swelling, pruritus |
| G:42 year male | Prick 6 pins on the right side of thigh inside | Prick 6 pins in the left side of thigh inside | Not reaction | Not reaction |
| H:44 year women | Prick 8 pins on the abdominal part right side | Prick 8 pins in the abdominal part left side | Not reaction | The pain pruritus |
| I:53 year male | Prick 8 pins in the abdominal part left side | Prick 8 pins on the abdominal part right side | Not reaction | The pain pruritus |
| J:55 year women | Prick 8 pins on the abdominal part right side | Prick 8 pins in the abdominal part left side | Not reaction | Pain after the acupuncture |
From the result of above table 3 as can be seen, because the lubrication of silver, the pin that scribbles nanometer silver of the present invention does not have the sensation of pain when pinprick is gone into and extract, and simultaneously, after the acupuncture, any is arranged or do not have pruritus, swelling or anaphylaxis with pin of the present invention.
Test case 4: the test of the decomposition effect of body fat
With pin that scribbles nanometer silver of the present invention and previous stainless pin adiposis patient is carried out electrical acupuncture test one month, the variation of comparative analysis patient body weight then.The result is as shown in table 4.
Table 4
| Clinical volunteer | Stainless pin | Scribble the pin of nanometer silver | By with scribbling nanometer silver | By using the stainless pin acupuncture |
| Pin acupuncture and the body weight that reduces | And the body weight that reduces | |||
| A:19 year male's height: 180cm body weight: 118kg | Abdominal part, back, thigh inside; Acupuncture three times weekly in one month | Reduce 10kg | ||
| B:16 year women's height: 168cm body weight: 87kg | Abdominal part, back, thigh inside; Acupuncture three times weekly in one month | Reduce 13kg | ||
| C:26 year male's height: 179cm body weight: 110kg | Abdominal part, back, thigh inside; Acupuncture three times weekly in one month | Reduce 15kg | ||
| D:28 year women's height: 169cm body weight: 81kg | Abdominal part, back, thigh inside; Acupuncture three times weekly in one month | Reduce 5kg | ||
| E:32 year male's height: 173cm body weight: 98kg | Abdominal part, back, thigh inside; Acupuncture three times weekly in one month | Reduce 11kg | ||
| F： | Abdominal part, back is big | Reduce |
| 39 years old women's height: 164cm body weight: 87kg | Lower limb inside; Acupuncture three times weekly in one month | 6kg | ||
| G:46 year male's height: 169cm body weight: 96kg | Abdominal part, back, thigh inside; Acupuncture three times weekly in one month | Reduce 12kg | ||
| H:48 year women's height: 156cm body weight: 79kg | Abdominal part, back, thigh inside; Acupuncture three times weekly in one month | Reduce 3kg | ||
| I:56 year male's height: 167cm body weight: 96kg | Abdominal part, back, thigh inside; Acupuncture three times weekly in one month | Reduce 10kg | ||
| J:57 year women's height: 155cm body weight: 86kg | Abdominal part, back, thigh inside; Acupuncture three times weekly in one month | Reduce 5kg |
From the result of above table 4 as can be seen, when carrying out electronic stimulation and use pin is placed on the member of the test group at ear position with the pin that scribbles nanometer silver of the present invention, its amount of losing weight is more than 10kg, and carry out the member of the test group of electronic stimulation with stainless pin, its amount of losing weight less than 10kg. in addition, carry out that group of electronic stimulation with pin of the present invention, the reduction rapidly of fat can be determined by CT scan in the health.The speed of removing body fat with the pin that scribbles nanometer silver of the present invention is than fast with traditional stainless pin, this statement of facts, and pin of the present invention promptly dissolves intravital fat because of good electric conductivity and heat conductivity.
Test case 5: pain test (3)
The pumping needle of preparing in this example that scribbles nanometer silver is used to treat in the general hospital inflammatory diseases patient for a long time.Patient organizes comparison check to the reaction of pin of the present invention with a control, and the result is as shown in table 5.
Table 5
| Clinical volunteer | The rustless steel entry needle | Scribble the entry needle of nanometer silver | Scribble the sensation of the entry needle of nanometer silver | The sensation of rustless steel entry needle |
| A:19 year andropathy: cellulitis | Antibiotic injection, the morning | Antibiotic injection, evening | Not reaction | Pain |
| B:18 year women's diseases: peritonitis | Antibiotic injection, Ringer's mixture injection, evening | Antibiotic injection, Ringer's mixture injection, the morning | Insignificant pain | Pain |
| C:28 year andropathy: vehicle accident | Antibiotic injection, Ringer's mixture injection, analgesic injection, evening | Antibiotic injection, Ringer's mixture injection, analgesic injection, the morning | Not reaction | Twinge |
| D:29 year women's diseases: cecitis | Antibiotic injection, Ringer's mixture injection, the morning | Antibiotic injection, Ringer's mixture injection, evening | Not reaction | Pain |
| E:36 year andropathy: vehicle accident | Antibiotic injection, analgesic injection, evening | Antibiotic injection, analgesic injection, the morning | Not reaction | Twinge |
| F:39 year women's diseases: cancer | Antibiotic injection, Ringer's mixture injection, analgesic injection, evening | Antibiotic injection, Ringer's mixture injection, analgesic injection, the morning | Not reaction | Pain |
| G:42 year andropathy: the operation of stomach | Antibiotic injection, Ringer's mixture injection, evening | Antibiotic injection, Ringer's mixture injection, the morning | Not reaction | Twinge |
| H:48 year women's diseases: arthritis | Antibiotic injection, the morning | Antibiotic injection, evening | Not reaction | Pain |
| I:56 year andropathy: bronchitis | Antibiotic injection, the morning | Antibiotic injection, evening | Not reaction | Twinge |
| J:55 year women's diseases: arthritis | Antibiotic injection, analgesic injection, the morning | Antibiotic injection, analgesic injection, evening | Not reaction | Pain |
From the result of table 5 as can be seen, compare with previous rustless steel entry needle, the entry needle that scribbles nanometer silver of the present invention has fabulous antibacterial functions.Simultaneously, because the lubrication of nano silver particles, pin of the present invention is penetrating human body skin, blood vessel or muscle and is extracting or during woods Ge Shi injection, pain significantly reduces from all subcutaneous tissue, muscular tissue, intravascular tissue.This is that therefore, when pinprick is gone into organizing of human body, the damage of skin, muscle, nerve and blood vessel, friction and promotion will reduce because on the entry needle of the present invention the nano silver particles coating is arranged.
Test case 6: pain test (4)
About the patient who takes one's test in the test case 5, check pain and sensation when they penetrate or extract entry needle, and pin is extracted reaction and the situation that occurs on the skin of back.The result is as shown in table 6.
Table 6
| Clinical volunteer | The rustless steel entry needle | Scribble the entry needle of nanometer silver | After the entry needle that scribbles nanometer silver is pulled out | After the rustless steel entry needle is pulled out |
| A:19 year andropathy: cellulitis | Antibiotic injection, the morning | Antibiotic injection, evening | Not reaction | Not reaction |
| B:18 year women | Antibiotic injection, woods | Antibiotic injection, woods | Slight swelling | Allergy, pruritus, |
| Disease: peritonitis | The grignard solution injection, evening | The grignard solution injection, the morning | Swelling | |
| C:28 year andropathy: vehicle accident | Antibiotic injection, Ringer's mixture injection, analgesic injection, evening | Antibiotic injection, Ringer's mixture injection, analgesic injection, the morning | Not reaction | Pruritus, swelling |
| D:29 year women's diseases: cecitis | Antibiotic injection, Ringer's mixture injection, the morning | Antibiotic injection, Ringer's mixture injection, evening | Not reaction | Pruritus, swelling |
| E:36 year andropathy: vehicle accident | Antibiotic injection, analgesic injection, evening | Antibiotic injection, analgesic injection, the morning | Not reaction | Pruritus, swelling |
| F:39 year women's diseases: cancer | Antibiotic injection, Ringer's mixture injection, analgesic injection, evening | Antibiotic injection, Ringer's mixture injection, analgesic injection, the morning | Not reaction | Allergy, pruritus, swelling |
| G:42 year andropathy: the operation of stomach | Antibiotic injection, Ringer's mixture injection, evening | Antibiotic injection, Ringer's mixture injection, the morning | Not reaction | Pruritus, swelling |
| H:48 year women's diseases: arthritis | Antibiotic injection, the morning | Antibiotic injection, evening | Not reaction | Swelling |
| I:56 year andropathy: bronchitis | Antibiotic injection, the morning | Antibiotic injection, evening | Not reaction | Swelling, pain |
| J:55 year women's diseases: arthritis | Antibiotic injection, the analgesic injection, on | Antibiotic injection, analgesic injection, evening | Not reaction | Pruritus |
| Noon | On |
As can be seen from Table 6, most patient is thought the time had coarse and scorching hot sensation with former entry needle in injection, and the entry needle that scribbles nanometer silver of the present invention has reduced to have an acupuncture treatment or the pain when pulling out pin.Simultaneously, compare, under the situation with pin of the present invention, have an acupuncture treatment and pull out the very fast of wound healing that pin causes with previous entry needle.In addition, shown neither reactions such as for example swelling, allergy or pruritus, reaction that neither inflammation.
As mentioned above, of the present invention have antibiotic and medical needle no pain function, in the effect aspect antibiotic, sterilization, deodorization and the removal toxin is significant, when acupuncture, produce useful anion to stimulate blood circulation and inner secretions, antiviral and antianaphylactic effect are arranged, and can ease the pain apace and dissolve intravital fat.Simultaneously, because the fabulous lubrication of nanometer silver, the pain when pin of the present invention has reduced that pinprick is gone into human body.Especially during electrical acupuncture, even under low current intensity, pin of the present invention has shown good electrical conductivity and heat conductivity.
Claims (2)
1. medical needle of selecting from the group that comprises pumping needle, surgical needles and acupuncture needle, wherein, the diameter that scribbles the 0.01-50 micron thickness on this wire surface is the Nano silver grain of 0.1-300 nanometer.
2. medical needle of selecting from the group that comprises pumping needle, surgical needles and acupuncture needle, wherein, it is that the diameter of the 0.01-20% of pin weight is the Nano silver grain of 0.1-300 nanometer that this needle body contains weight.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020050013855 | 2005-02-19 | ||
| KR1020050013855A KR20060042115A (en) | 2004-09-23 | 2005-02-19 | Na no silver contain a spine |
| KR1020050021174A KR20060043621A (en) | 2004-10-07 | 2005-03-14 | Nano silver and contain syringe |
| KR1020050021174 | 2005-03-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101119698A true CN101119698A (en) | 2008-02-06 |
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ID=36916666
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2006800052207A Pending CN101119698A (en) | 2005-02-19 | 2006-01-05 | Medical needles having antibacterial and painless function |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JP2008529711A (en) |
| CN (1) | CN101119698A (en) |
| WO (1) | WO2006088288A1 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105682704A (en) * | 2013-10-31 | 2016-06-15 | 株式会社Ｅｆｒ | Needle and method for manufacturing same |
| CN114525562A (en) * | 2022-04-06 | 2022-05-24 | 内蒙古民族大学 | Mongolian medicine acupuncture needle and preparation method thereof |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| US9352119B2 (en) | 2012-05-15 | 2016-05-31 | Becton, Dickinson And Company | Blood control IV catheter with antimicrobial properties |
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| JP6511398B2 (en) * | 2013-10-31 | 2019-05-15 | 株式会社Ｅｆｒ | Needle and method of manufacturing the same |
| US9675793B2 (en) | 2014-04-23 | 2017-06-13 | Becton, Dickinson And Company | Catheter tubing with extraluminal antimicrobial coating |
| US10376686B2 (en) | 2014-04-23 | 2019-08-13 | Becton, Dickinson And Company | Antimicrobial caps for medical connectors |
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| JPH0788147A (en) * | 1993-09-24 | 1995-04-04 | Yoshihiro Somehara | Pressure type artery-vein/arterial hole stimulating medical treatment implement |
| DK0711113T3 (en) * | 1994-02-01 | 1997-09-22 | Theodor Krall | Process for the preparation of bactericidal / fungicidal plastic bodies |
| US5957862A (en) * | 1997-12-01 | 1999-09-28 | Lu; Cheng-Liang | Acupuncture device system and methods thereof |
| KR20040089036A (en) * | 2004-09-23 | 2004-10-20 | 양원동 | Nano silver contain a spine |
| KR20040096913A (en) * | 2004-10-07 | 2004-11-17 | 양원동 | Nano silver and perfume contain hospital mattress cover |
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2006
- 2006-01-05 JP JP2007556066A patent/JP2008529711A/en active Pending
- 2006-01-05 WO PCT/KR2006/000044 patent/WO2006088288A1/en active Application Filing
- 2006-01-05 CN CNA2006800052207A patent/CN101119698A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105682704A (en) * | 2013-10-31 | 2016-06-15 | 株式会社Ｅｆｒ | Needle and method for manufacturing same |
| CN105682704B (en) * | 2013-10-31 | 2019-09-17 | 株式会社Ｅｆｒ | The manufacturing method of needle |
| CN114525562A (en) * | 2022-04-06 | 2022-05-24 | 内蒙古民族大学 | Mongolian medicine acupuncture needle and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006088288A1 (en) | 2006-08-24 |
| JP2008529711A (en) | 2008-08-07 |
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