CN101112571A - Chinese traditional medicine composition for treating skin amyloidosis - Google Patents

Abstract

The present invention relates to a traditional Chinese medicine composition for treating cutaneous amyloidosis, which takes more than 10 Chinese herbal medicines of clematis root, puncturevine caltrop fruit, ground beetle, stings of Gleditsia sinensis etc. as the raw materials. The present invention has the effects of promoting blood circulation, removing blood stasis, removing dampness and moistening skin. Based on the differential treatment of the traditional Chinese medicine, the invention is developed by combining the latest scientific research results with the traditional Chinese medicine. The present invention aims at providing the traditional Chinese medicine composition for treating cutaneous amyloidosis. The present invention is characterized by accurate efficacy, safety, convenience, no toxicity or side effects and low price.

Description

A kind of Chinese medicine composition for the treatment of skin amyloidosis

Technical field

The present invention relates to a kind of Chinese medicine composition for the treatment of skin amyloidosis, is that a kind of skin amyloidosis for the treatment of is the Chinese medicine composition of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.

Background technology

Skin amyloidosis claims lichen sample and macule shape amyloidosis again.Be a kind of specific response that is, even structureless amyloid beta deposition does not involve a kind of chronic dermatosis of other organ in skin histology.The psoriasis, the toadskin category that belong to the traditional Chinese medical science.The cause of disease is still indeterminate, may be relevant with immunity with heredity, and be due to the protein metabolism disorder.The traditional Chinese medical science thinks that primary disease is the natural endowment deficiency, and is qi-blood disharmony, the heresy of diseases caused by exogenous pathogenic factor rheumatism, and the visitor stays strongly fragrant not going in skin, due to the consumption impairment of YIN blood, failure of skin and muscle to be nourished.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.

Summary of the invention

The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of skin amyloidosis.Have determined curative effect, safe ready, have no side effect, cheap characteristics.

The present invention is made by following raw materials by weight proportions:

0.1～2 part of 0.1～2 part of Fructus Atriplicis Sibiricae of 1.5～6 parts of Radix Saposhnikoviaes of Rhizoma Curcumae

0.1～2 part of 0.1～2 part of Spina Gleditsiae of 1.0～4 portions of Cortex Phellodendris of Radix Clematidis

0.1～1 part of 0.1～2 part of Eupolyphaga Seu Steleophaga of 1.0～4 parts of Pericarpium Citri Reticulataes of rhizoma sparganic

0.1～0.5 part of 0.1～2 portion of Scorpio of 1.0～4 parts of Radix Sophorae Flavescentiss of Cortex Dictamni.

The weight proportion of each crude drug of optimization formula of the present invention is:

0.5～1.5 part of 0.5～1.5 part of Fructus Atriplicis Sibiricae of 2.5～3.5 parts of Radix Saposhnikoviaes of Rhizoma Curcumae

0.5～1.5 part of 0.5～1.5 part of Spina Gleditsiae of 1.5～2.5 portions of Cortex Phellodendris of Radix Clematidis

0.3～0.7 part of 0.5～1.5 part of Eupolyphaga Seu Steleophaga of 1.5～2.5 parts of Pericarpium Citri Reticulataes of rhizoma sparganic

0.2～0.4 part of 0.5～1.5 portion of Scorpio of 1.5～2.5 parts of Radix Sophorae Flavescentiss of Cortex Dictamni.

The weight proportion of each crude drug of optimum formula of the present invention is:

1 part of 1 part of Fructus Atriplicis Sibiricae of 3 parts of Radix Saposhnikoviaes of Rhizoma Curcumae

1 part of 1 part of Spina Gleditsiae of 2 portions of Cortex Phellodendris of Radix Clematidis

0.5 part of 1 part of Eupolyphaga Seu Steleophaga of 2 parts of Pericarpium Citri Reticulataes of rhizoma sparganic

0.3 part of 1 portion of Scorpio of 2 parts of Radix Sophorae Flavescentiss of Cortex Dictamni.

Drug action mechanism among the present invention is as follows:

Rhizoma Curcumae nature and flavor hardship, suffering, temperature.Return liver, spleen channel.Have the circulation of qi promoting removing blood stasis with potent drugs, the removing food stagnancy pain relieving is changed poly-eliminating mass, the effect of antiearly pregnancy.Can treat that trusted subordinate's distending pain, lump in the abdomen, dyspepsia do not disappear, hepatosplenomegaly, abdominal pain due to blood stasis, amenorrhea due to stagnation of blood, cervical erosion, traumatic injury have a pain etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 995th page).

Radix Clematidis property of medicine suffering, salty, little hardship, temperature, mild toxicity.Return bladder, Liver Channel.Has expelling wind and removing dampness, the effect of removing obstruction in the collateral to relieve pain.Can treat rheumatic arthralgia, numb limbs and tense tendons, the contracture of muscle arteries and veins, joint stuffiness, beriberi swells and ache, malaria, the bone larynx of choking with sobs.And control phlegm retention and gather etc.(the 2276th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Rhizoma sparganic nature and flavor suffering, hardship, flat.Return liver, spleen channel.Has removing blood stasis, circulation of qi promoting, removing food stagnancy analgesic effect.Can treat lump in the abdomen, coagulation of QI-blood, trusted subordinate's pain, the food stagnation distending pain, the side of body expands down painful, amenorrhea, dysmenorrhea, puerperal abdominalgia with blood stasis, traumatic injury, skin ulcer is swollen hard, hepatosplenomegaly etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 69th page).

Cortex Dictamni property of medicine hardship, salty, cold.Return spleen, stomach warp.Has heat clearing and damp drying, dispelling wind for relieving itching, antidotal effect.Can treat the rubella eczema due to the wind heat noxious dampness, scabies, jaundice, rheumatism pyretic arthralgia etc.(the 1019th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Saposhnikoviae nature and flavor suffering, sweet, temperature.Return bladder, liver, spleen channel.Have inducing diaphoresis to dispel wind, win and wet, the effect of relieving convulsion.Can treat headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus etc.(the 117th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).

Cortex Phellodendri property of medicine hardship, cold.Return kidney, bladder, large intestine channel.Has heat clearing and damp drying, the effect of eliminating fire and detoxication.Can treat hygropyretic dysentery, have loose bowels, jaundice, nocturnal emission, stranguria with turbid discharge, leukorrhagia, hectic fever due to YIN-deficiency consumptive fever ， Wei Bi, and aphtha of the mouth and tongue, conjunctival congestion and swelling pain, skin sore, skin eczema etc.(the 2823rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Pericarpium Citri Reticulatae property of medicine suffering, hardship, temperature.Return spleen, stomach, lung meridian.Having in the accent of regulating the flow of vital energy stopping nausea and vomiting by lowering the adverse flow of QI, the effect of drying dampness to eliminate phlegm.It is full vexed to treat chest and diaphragm, abdominal distention, anorexia, vomiting, hiccup; Cough with copious phlegm.Acute mastitis from the beginning of etc.(the 1668th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Sophorae Flavescentis property of medicine hardship, cold.GUIXIN, lung, kidney, large intestine channel.Has heat clearing and damp drying, the effect of wind dispelling insecticide.Can treat damp-heat dysentery, discharging fresh blood stool, jaundice, dysuria, edema, leukorrhagia, pudendal pruritus, scabies, leprosy, skin pruritus, noxious dampness skin infection.(the 1758th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Fructus Atriplicis Sibiricae property of medicine hardship, suffering, flat.Return liver, lung meridian.Have suppressing the hyperactive liver, resolving depression makes eye bright, the effect of dispeling the wind.Can treat headache, dizzy, distending pain in the chest and hypochondrium, distending pain of the breast ， mass in the abdomen, conjunctival congestion cataracta, rubella pruritus, vitiligo, carbuncle, scrofula etc.(the 1844th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Spina Gleditsiae property of medicine suffering, temperature.Return liver, lung, stomach warp.Have the saturating pus of detumescence, search wind, parasiticidal effect.Can treat swollen ulcer drug, scrofula, leprosy, skin ulcer rash stubborn dermatitis, puerperal hypogalactia, placenta retention etc.(the 1595th page of Shanghai science tech publishing house write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Eupolyphaga Seu Steleophaga nature and flavor are salty, cold, slightly poisonous.Return Liver Channel.Has promoting blood circulation to remove blood stasis, inducing menstruation to relieve menalgia, the abdominal mass that disappears, the effect of reunion of bone.Can treat cervical cancer, multiple myeloma, various tumors such as leukemia; And be used for lump in the abdomen, and amenorrhea due to stagnation of blood, postnatal blood stasis stomachache, traumatic injury, swollen and rigid tongue, congenital deformity of the tongue, the muscles and bones folding is hindered hepatosplenomegaly, an emaciation due to blood disorder, scarlet fever, erysipelas etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 91st page).

Scorpio nature and flavor suffering, flat; Poisonous.Return Liver Channel.Has endogenous wind stopping spasmolytic, dispersing pathogen accumulation, the effect of removing obstruction in the collateral to relieve pain.Can treat infantile convulsion, tic spasm, middle air port

, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula etc.(the 111st page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).

The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Scorpio, Rhizoma Curcumae and Eupolyphaga Seu Steleophaga; With Cortex Dictamni, Fructus Atriplicis Sibiricae, Spina Gleditsiae, Radix Sophorae Flavescentis, rhizoma sparganic and Radix Clematidis is ministerial drug: with Radix Saposhnikoviae, Cortex Phellodendri and Pericarpium Citri Reticulatae is adjuvant.All medicines are harmonious, and are total to the tool blood circulation promoting and blood stasis dispelling, the effect of dehumidifying skin moistening.The treatment skin amyloidosis has determined curative effect, has no side effect taking convenience, cheap characteristics.

Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment skin amyloidosis of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.

2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.

3, the present invention not only can effectively treat skin amyloidosis, and the prevention of skin amyloidosis is also had good effect, and the treatment skin amyloidosis has determined curative effect, has no side effect taking convenience, cheap characteristics.

For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment skin amyloidosis; Treatment skin amyloidosis patient 25 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.13 examples of fully recovering account for 52%, and 9 examples that take a turn for the better account for 36%, and more 3 examples do not account for 12%, and total effective rate reaches 88%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

The embodiment decoction is pressed following weight weighting raw materials:

1 part of 1 part of Fructus Atriplicis Sibiricae of 3 parts of Radix Saposhnikoviaes of Rhizoma Curcumae

1 part of 1 part of Spina Gleditsiae of 2 portions of Cortex Phellodendris of Radix Clematidis

0.5 part of 1 part of Eupolyphaga Seu Steleophaga of 2 parts of Pericarpium Citri Reticulataes of rhizoma sparganic

0.3 part of 1 portion of Scorpio of 2 parts of Radix Sophorae Flavescentiss of Cortex Dictamni.

Preparation method is to get the above-mentioned raw materials medicine to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment skin amyloidosis that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1. Chinese medicine composition for the treatment of skin amyloidosis is characterized in that it is made by following raw materials by weight proportions:

0.1～2 part of 0.1～2 part of Fructus Atriplicis Sibiricae of 1.5～6 parts of Radix Saposhnikoviaes of Rhizoma Curcumae

0.1～2 part of 0.1～2 part of Spina Gleditsiae of 1.0～4 portions of Cortex Phellodendris of Radix Clematidis

0.1～1 part of 0.1～2 part of Eupolyphaga Seu Steleophaga of 1.0～4 parts of Pericarpium Citri Reticulataes of rhizoma sparganic

0.1～0.5 part of 0.1～2 portion of Scorpio of 1.0～4 parts of Radix Sophorae Flavescentiss of Cortex Dictamni.

2. a kind of Chinese medicine composition for the treatment of skin amyloidosis according to claim 1, wherein the weight proportion of each crude drug is:

0.5～1.5 part of 0.5～1.5 part of Fructus Atriplicis Sibiricae of 2.5～3.5 parts of Radix Saposhnikoviaes of Rhizoma Curcumae

0.5～1.5 part of 0.5～1.5 part of Spina Gleditsiae of 1.5～2.5 portions of Cortex Phellodendris of Radix Clematidis

0.3～0.7 part of 0.5～1.5 part of Eupolyphaga Seu Steleophaga of 1.5～2.5 parts of Pericarpium Citri Reticulataes of rhizoma sparganic

0.2～0.4 part of 0.5～1.5 portion of Scorpio of 1.5～2.5 parts of Radix Sophorae Flavescentiss of Cortex Dictamni.

3. a kind of Chinese medicine composition for the treatment of skin amyloidosis according to claim 1, wherein the weight proportion of each crude drug is:

1 part of 1 part of Fructus Atriplicis Sibiricae of 3 parts of Radix Saposhnikoviaes of Rhizoma Curcumae

1 part of 1 part of Spina Gleditsiae of 2 portions of Cortex Phellodendris of Radix Clematidis

0.5 part of 1 part of Eupolyphaga Seu Steleophaga of 2 parts of Pericarpium Citri Reticulataes of rhizoma sparganic

0.3 part of 1 portion of Scorpio of 2 parts of Radix Sophorae Flavescentiss of Cortex Dictamni.