CN101095805A - Medicine made by onion and aloe and method for preparing the same - Google Patents
Medicine made by onion and aloe and method for preparing the same Download PDFInfo
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- CN101095805A CN101095805A CNA2007100660092A CN200710066009A CN101095805A CN 101095805 A CN101095805 A CN 101095805A CN A2007100660092 A CNA2007100660092 A CN A2007100660092A CN 200710066009 A CN200710066009 A CN 200710066009A CN 101095805 A CN101095805 A CN 101095805A
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- allii cepae
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Abstract
Disclosed is a medicament and process for preparation, wherein the medicament is prepared from onion and aloe through steps of proportioning, mixing and disintegrating, extracting, ultramicro disintegration, enzymolyzing, deslagging, concentrating, drying, disintegrating and forming. The medicament can be made into capsules or tablets directly from fresh onion and aloe as the raw materials, and can be used for treating hyperlipoidemia and diabetes.
Description
Affiliated technical field:
The present invention relates to the biological product technology, particularly a kind of medicine made from Bulbus Allii Cepae and Aloe and preparation method thereof.
Background technology:
Bulbus Allii Cepae (Allium cepal), it is Liliaceae Allium bulb herbaceous plant, contain carbohydrate, mineral, vitamin, often eat raw fresh Bulbus Allii Cepae to blood lipid regulation, blood glucose, vascular tone, bringing high blood pressure down has certain effect, recommend according to world NNFA, everyone ate the effect that can satisfy above-mentioned functions more than the Bulbus Allii Cepae 80g in one day raw.Aloe (Aloe) belongs to the Liliaceae Aloe, and its medical value just was familiar with by people as far back as 36～68 years Christian eras, and it has convergence, hypnosis, keeps fit, the effect of clearing stomach, relieving constipation.Its chemical constituent has aldehydes matter, mainly contains: aloe-emodin (aloe-emodin), sugar (containing single, double and polysaccharide), flavonoid, vitamin, aminoacid (eight kinds of necessary aminoacid that contain needed by human body), organic acid, mineral, Aloin A etc.Aloe not only has medical value, also is a kind of spendable vegetable simultaneously.
Above-mentioned two kinds of article, its moisture has special odor up to more than 90% under fresh state, eat raw to reach that to have the dosage of preventing and curing diseases be not something that most of people can accept.The common expectation that safe and effective treatment medicine is people is extracted in exploration from food.Chinese patent literature CN931005132 discloses the method that Bulbus Allii Cepae is developed as the series of products of single and compound recipe, but the compatibility complexity, the technology ambiguity is difficult to carry out.
Summary of the invention:
The objective of the invention is to overcome the deficiencies in the prior art, disclose a kind of medicine made from Bulbus Allii Cepae and Aloe and preparation method thereof, can keep the biological activity of two kinds of article to greatest extent, accomplish again to be convenient for carrying, edible as far as possible.By compatibility, make the useful effect of two kinds of article obtain complementation, bring into play harmonious health care and therapeutic effect.
The present invention is achieved in that to be that raw material carries out compatibility with fresh Bulbus Allii Cepae and Aloe directly, by get the raw materials ready, mix pulverizing, extraction, grinding, concentrate, dry, pulverize operation such as molding and step is made medicine, obtain product.
Operation, the step of drug products prescription and preparation method are:
1, prescription:
Bulbus Allii Cepae and aloetic mixed proportion, Bulbus Allii Cepae accounts for 70%～85%, and Aloe accounts for 30%～15%.
2, preparation method:
(1) get the raw materials ready, Bulbus Allii Cepae removes root, leaf, and Aloe removes root, thorn, and surperficial earth is cleaned up, and dries standby.
(2) mix to pulverize, Bulbus Allii Cepae and Aloe are weighed according to the above ratio is crushed to 40～60 orders after mixing.
(3) extract, mixed powder is minced is written into the ultrasonic extraction jar, is under 40 ℃～50 ℃ in temperature, extracts 20～35 minutes.
(4) micronizing will be poured colloid mill into through the mixture that extracts and grind into powder to 5～20 μ m fineness.
(5) enzymolysis adds pectase and cellulase in the process mixture of micronizing, temperature is controlled between 30 ℃～45 ℃, 2 hours time.
(6) slagging-off, the material of process enzymolysis removes slag with the squeezing of piston type squeezer.
(7) concentrate, will squeeze the juice is written into vacuum concentration pan, is concentrated into the 1/4-1/3 of original volume below 60 ℃ in vacuum 0.08～0.06mPa, temperature.
(8) drying is sent qualified concentrated solution into microwave vacuum dryer, is dried to the block of the similar redness of moisture＜8% below 60 ℃ in vacuum 0.08～0.06mPa, temperature.
(9) pulverize molding, it is standby that the block of dry gained is crushed to 80～120 orders, or pulverize directly filled capsules of back, or should carry out coating behind the direct compression.Purpose is to reduce the special odor of Bulbus Allii Cepae.
A whole set of preparation technology's method provided by the invention is physical refining process, therefore do not add any other adjuvant and antiseptic, what produce is the product of safe without toxic side effect, in the production process except that a spot of water for cleaning is arranged, do not have other three waste discharges, reach relevant environmental requirement fully.Product is nontoxic after testing, and no teratogenesis has certain treatment and health-care effect to hyperlipidemia, diabetes and hypertension, and every gram is equivalent to fresh feed 12～15 grams.
The specific embodiment:
Below by embodiment in detail the present invention is described in detail:
Embodiment 1
1. take by weighing through arrangement, clean and 70 kilograms of the Bulbus Allii Cepaes that drain away the water, 30 kilograms of Aloes are standby.
2. standby Bulbus Allii Cepae, Aloe are put into pulverizer and be crushed to 40 orders.
3. mixed powder is minced and put into 250L ultrasonic extraction jar extraction 20 minutes, temperature is controlled at 40 ℃.
4. the material that passes through ultrasonic extraction is further broken with colloid mill, and abrasive disk space is controlled in the 20 μ m.
5. material is put into preserving jar, add pectase 1.5 grams respectively, cellulase 3 restrains, and stirs, and places 2 hours under 40 ℃ of conditions, removes the gred with the piston type squeezer in the back.
6. the material for preparing is written into vacuum concentration pan, under 45 ℃ of temperature, pressure 0.08mPa condition, stock solution is concentrated into 1/4 of original volume.
7. concentrated solution is inserted vacuum microwave drier,, be dried to moisture under the pressure 0.08mPa condition less than 8% thing piece, heavily about 7.6 kilograms 45 ℃ of temperature.Every gram extract is equivalent to fresh feed 13 grams.
8. the material that drying is obtained is filled to capsule No. 0 after being crushed to 100 orders, in the capsule thing weight 500mg (± 15mg).
Embodiment 2
1. take by weighing through arrangement, clean and 85 kilograms of the Bulbus Allii Cepaes that drain away the water, 15 kilograms of Aloes are standby.
2. standby Bulbus Allii Cepae, Aloe are put into pulverizer and be crushed to 60 orders.
3. mixed powder is minced and put into 250L ultrasonic extraction jar extraction 35 minutes, temperature is controlled at 50 ℃.
4. the material that passes through ultrasonic extraction is further broken with colloid mill, and abrasive disk space is controlled in the 20 μ m.
5. material is put into preserving jar, add pectase 1.5 grams respectively, cellulase 3 restrains, and stirs, and places 2 hours under 60 ℃ of conditions, removes the gred with the piston type squeezer in the back.
6. the material for preparing is written into vacuum concentration pan, under 60 ℃ of temperature, pressure 0.06mPa condition, stock solution is concentrated into 1/3 of original volume.
7. concentrated solution is inserted vacuum microwave drier,, be dried to moisture under the pressure 0.06mPa condition less than 8% thing piece 60 ℃ of temperature.Heavily about 7.6 kilograms.Every gram extract is equivalent to fresh feed 13 grams.
8. the material that drying is obtained is filled to capsule No. 0 after being crushed to 100 orders, in the capsule thing weight 500mg (± 15mg).
Above-mentioned two embodiment only be for clearly demonstrate that the present invention does for example, but not to the qualification of embodiments of the present invention.Fabricating technology scheme for affiliated field; obviously can make other multi-form variation on the basis of the above description; the product of preparation different dosage form; here need not all embodiments are given an example one by one; and the product of these variations and different dosage form thereof still is among protection scope of the present invention.
Claims (10)
1, a kind of medicine made from Bulbus Allii Cepae and Aloe is characterized in that, is that material combination is prepared from fresh Bulbus Allii Cepae and Aloe,
2, medicine as claimed in claim 1 is characterized in that, the percentage by weight of Bulbus Allii Cepae and Aloe compatibility is: Bulbus Allii Cepae 70%～85%, Aloe 30%～15%.
3, a kind of process for preparing medicine made from Bulbus Allii Cepae and Aloe is characterized in that, the order and the step of preparation method are:
(1) get the raw materials ready, Bulbus Allii Cepae removes root, leaf, and Aloe removes root, thorn, clean dry standby;
(2) mix pulverizing, Bulbus Allii Cepae and Aloe are mixed in proportion the back pulverizing;
(3) extract, mixed powder is minced is written into the extraction of ultrasonic extraction jar;
(4) micronizing will be poured colloid mill into through the mixture that extracts and grind into powder;
(5) enzymolysis adds pectase and cellulase enzymolysis in the process mixture of micronizing;
(6) slagging-off, the material of process enzymolysis removes slag with the squeezing of piston type squeezer;
(7) concentrate, will squeezing the juice, it is concentrated to be written into vacuum concentration pan;
(8) drying is sent qualified concentrated solution into the microwave vacuum dryer drying;
(9) pulverize molding, the block of dry gained is pulverized molding.
4, preparation method as claimed in claim 3 is characterized in that, mixing smashing fineness is 40～60 orders,
5, preparation method as claimed in claim 3 is characterized in that, extraction time is 20～35 minutes, and extracting temperature is 40 ℃～50 ℃.
6, preparation method as claimed in claim 3 is characterized in that, micronizing fineness 5～20 μ m.
7, preparation method as claimed in claim 3 is characterized in that, hydrolysis temperature is controlled between 30 ℃～45 ℃, and enzymolysis time is 2 hours.
8, preparation method as claimed in claim 3 is characterized in that, at vacuum 0.08～0.06mPa, and 45 ℃ of temperature～concentrate below 60 ℃.
9, preparation method as claimed in claim 3 is characterized in that, at vacuum 0.08～0.06mPa, and 45 ℃ of temperature～be dried to below 60 ℃ moisture＜8%.
10, preparation method as claimed in claim 3 is characterized in that, pulverizes molding and is dry thing is crushed to behind 80～100 orders directly filled capsules, or carry out coating behind the direct compression.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007100660092A CN101095805A (en) | 2007-06-29 | 2007-06-29 | Medicine made by onion and aloe and method for preparing the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007100660092A CN101095805A (en) | 2007-06-29 | 2007-06-29 | Medicine made by onion and aloe and method for preparing the same |
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| Publication Number | Publication Date |
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| CN101095805A true CN101095805A (en) | 2008-01-02 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNA2007100660092A Pending CN101095805A (en) | 2007-06-29 | 2007-06-29 | Medicine made by onion and aloe and method for preparing the same |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102224931A (en) * | 2011-06-01 | 2011-10-26 | 四川科伦新光健康药业有限公司 | Composition assisting in reduction of blood sugar |
| CN101671371B (en) * | 2009-10-15 | 2012-09-05 | 江南大学 | Method for extracting flavonoid compound from onion skins |
| CN104286877A (en) * | 2013-07-20 | 2015-01-21 | 浙江圣氏生物科技有限公司 | Bamboo shoot dietary fiber chewing tablets and preparation method thereof |
| CN104623214A (en) * | 2015-01-19 | 2015-05-20 | 张香平 | Traditional Chinese medicine composition and preparation method thereof |
| CN106137976A (en) * | 2015-04-21 | 2016-11-23 | 吴琦 | Chinese medicinal granule microwave preparation |
-
2007
- 2007-06-29 CN CNA2007100660092A patent/CN101095805A/en active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101671371B (en) * | 2009-10-15 | 2012-09-05 | 江南大学 | Method for extracting flavonoid compound from onion skins |
| CN102224931A (en) * | 2011-06-01 | 2011-10-26 | 四川科伦新光健康药业有限公司 | Composition assisting in reduction of blood sugar |
| CN102224931B (en) * | 2011-06-01 | 2013-03-06 | 四川科伦新光健康药业有限公司 | Composition assisting in reduction of blood sugar |
| CN104286877A (en) * | 2013-07-20 | 2015-01-21 | 浙江圣氏生物科技有限公司 | Bamboo shoot dietary fiber chewing tablets and preparation method thereof |
| CN104623214A (en) * | 2015-01-19 | 2015-05-20 | 张香平 | Traditional Chinese medicine composition and preparation method thereof |
| CN104623214B (en) * | 2015-01-19 | 2018-02-23 | 张香平 | A kind of Chinese medicine composition and preparation method thereof |
| CN106137976A (en) * | 2015-04-21 | 2016-11-23 | 吴琦 | Chinese medicinal granule microwave preparation |
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Open date: 20080102 |