CN101077360B - Medicinal composition for treating sugar diabetes skin ulcer and preparation method thereof - Google Patents
Medicinal composition for treating sugar diabetes skin ulcer and preparation method thereof Download PDFInfo
- Publication number
- CN101077360B CN101077360B CN2006100815328A CN200610081532A CN101077360B CN 101077360 B CN101077360 B CN 101077360B CN 2006100815328 A CN2006100815328 A CN 2006100815328A CN 200610081532 A CN200610081532 A CN 200610081532A CN 101077360 B CN101077360 B CN 101077360B
- Authority
- CN
- China
- Prior art keywords
- skin ulcer
- ulcer
- pharmaceutical composition
- parts
- seu calvatia
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention discloses one kind of medicine composition for treating diabetic skin ulcer. The mechanical composition is prepared with purslane 400-1200 weight portions, natural indigo 100-600 weight portions and puff ball 400-1200 weight portions. It has the functions of removing necrosis, promoting tissue regeneration, clearing away heat and toxic material, reducing swelling and relieving pain, and can treat diabetic skin ulcer and skin injury, including great area ulcer and injury in effective rate over 97 %.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, relate in particular to a kind of main be the pharmaceutical composition and preparation method thereof of the treatment diabetic ulcer that becomes of feedstock production with the Chinese herbal medicine, belong to the field of Chinese medicines.
Background technology
Diabetes, the traditional Chinese medical science diabetes, drink polyuria, polyphagia polyphagia more.The upper, middle and lower three types of diabetes is arranged, on many thirsty polydipsia that disappear, due to deficiency of lung-YIN; In disappear for the polyphagia polyphagia, due to deficiency of stomach-YIN; Diabetes due to kidney-deficiency is for drinking polyuria more, be due to the deficiency of the kidney yin, lung, stomach, kidney three dirty mansion hyperactivity of fire caused by deficiency of YIN, and the deficiency of YIN is given birth to interior-heat, and causes the qiactivity of triple energizer functional disorder and form quench one's thirst (being the doctor trained in Western medicine diabetes).
It is reported that the diabetics of China only accounted for 1.9% of population in 1975,, nearly be increased to 10% by 1998.That is to say just have 1 people to suffer from diabetes among per 10 adults.Diabetes are quite general in the old people.The position that common complication is exactly foot and ankle joint pressurized in this disease develops into skin ulcer.It is more and more serious that this ulcer may become, thus make infect and the ischemia situation more obvious.Because disturbance of blood circulation and anti-infection ability descend, many diabetes patient's foots fester and are difficult to cure, because the diabetes endarteritis has caused ischemia and unmanageable bacterial infection.As a result, in most of the cases, the patient must amputation.Investigation shows, the diabetics that half is arranged is in excision wherein behind foot, can lose the another foot in 3 years.So press for a kind of pharmaceutical composition that can effectively treat diabetic ulcer at present, can make diabetic ulcer remove the huge misery and the danger of amputation from.
Summary of the invention
Technical problem to be solved by this invention is to overcome the deficiencies in the prior art, and a kind of new pharmaceutical composition that can effectively cure diabetic skin ulcer is provided.
Technical problem to be solved by this invention realizes by following technological approaches:
A kind of pharmaceutical composition for the treatment of diabetic skin ulcer, form by following bulk drugs:
Herba Portulacae 400-1200 part, Indigo Naturalis 100-600 part and Lasiosphaera Seu Calvatia 400-1200 part.
Preferably, the weight portion of each crude drug is: 600 parts of Herba Portulacaes, 300 parts of Indigo Naturaliss, 600 parts of Lasiosphaera Seu Calvatia.
In order to reach better therapeutic effect, also can contain the Borneolum Syntheticum with the 0-400 weight portion in the aforementioned pharmaceutical compositions, be preferably the Borneolum Syntheticum that contains 20 weight portions.
Pharmaceutical composition of the present invention based on Chinese medicine and pharmacy to pathogenetic research of diabetic ulcer deep layer and Therapeutic Principle thereof, simultaneously according to the pharmaceutical research achievement, filter out the crude drug of heat-clearing and toxic substances removing, putrefaction-removing granulation-promoting, reducing swelling and alleviating pain, according to the theory of Chinese medical science prescription, be prepared from according to certain weight proportion.
Herba Portulacae: acid is cold, has the effect of heat-clearing and toxic substances removing, diffusing blood detumescence.
Indigo Naturalis: salty-cold, have the effect of heat-clearing and toxic substances removing, removing heat from blood.
Lasiosphaera Seu Calvatia: hot flat, have the effect of removing heat from the lung and relieving sorethroat, detoxifcation, hemostasis.
Borneolum Syntheticum: arduous, cold. have logical all keys, the strongly fragrant work of loosing, the effect of reducing swelling and alleviating pain.
Pharmaceutical composition of the present invention has the effect of putrefaction-removing granulation-promoting, heat-clearing and toxic substances removing, reducing swelling and alleviating pain, can effectively treat diabetic ulcer and skin injury, much no matter patient's skin ulcer face has, do not operate on, do not make skin graft, not amputation, the patient does not have any misery in the therapeutic process, and total effective rate reaches more than 97%.
The used raw material of the present invention all can be bought from common pharmacy and obtain, and specification all meets national medical standard.
Preparation of drug combination method of the present invention is as follows:
Take by weighing each raw material by following weight proportion: Herba Portulacae 400-1200 part, Indigo Naturalis 100-600 part and Lasiosphaera Seu Calvatia 400-1200 part; With mix homogeneously behind the above-mentioned raw materials crushing screening, promptly.
Usage and consumption: after patient's ulcer place cleaned up, get medicine of the present invention an amount of (consumption can be adjusted flexibly according to situations such as age of the size of skin ulcer face, patient, body weight, the state of an illness) and apply the affected part, the wrapping of external gauze was changed dressings once on the 3rd.
Further describe the present invention by the following examples, it should be understood that these embodiment only are used for the purpose of illustration, never limit the scope of the invention.
The specific embodiment
Embodiment 1
Take by weighing each raw material (unit: g): Herba Portulacae 400, Indigo Naturalis 100 and Lasiosphaera Seu Calvatia 400 by following weight proportion; With mix homogeneously behind the above-mentioned raw materials crushing screening, promptly.
Embodiment 2
Take by weighing each raw material (unit: g): Herba Portulacae 1200, Indigo Naturalis 600, Lasiosphaera Seu Calvatia 1200 by following weight proportion; With mix homogeneously behind the above-mentioned raw materials crushing screening, promptly.
Embodiment 3
Take by weighing each raw material (unit: g): 600 parts of Herba Portulacaes, 300 parts of Indigo Naturaliss, 600 parts of Lasiosphaera Seu Calvatia by following weight proportion; With mix homogeneously behind the above-mentioned raw materials crushing screening, promptly.
Embodiment 4
Take by weighing each raw material (unit: g): Herba Portulacae 600, Indigo Naturalis 300, Lasiosphaera Seu Calvatia 600, Borneolum Syntheticum 20 by following weight proportion; With mix homogeneously behind the above-mentioned raw materials crushing screening, promptly.
Test the clinical observation on the therapeutic effect test of routine medicine composite for curing diabetic skin ulcer of the present invention
One, physical data
Accept diabetic skin ulcer patient 126 examples altogether for medical treatment, wherein male 68 examples, women 58 examples at 32～78 years old age, 62 years old mean age, are the out-patient.
Two, trial drug
For the reagent thing: the powder that the embodiment of the invention 1 is prepared.
Three, Therapeutic Method
After patient's skin ulcer place cleaned up, get medicine of the present invention and apply the affected part in right amount, the wrapping of external gauze was changed dressings once on the 3rd.
Four, efficacy assessment standard
Produce effects: medication is after 7 days, and clinical Signs disappears substantially.
Effectively: medication is after 7 days, and clinical Signs is most of to disappear.
Invalid: medication is after 7 days, and clinical Signs does not have change.
Five, model case
1, name: Wu Jigui, sex: man the age: 56 years old, May Day farm five teams.
When October 18 went to a doctor in 2004, suffered from diabetes 8 years, the right crus of diaphragm mother refers to and instep two place's ulcer that after inspection, cleaning skin ulcer face reuse medicine of the present invention is added medicine to five times earlier, and ulcer heals entirely.
2, name: horse YULAN, sex: woman's age: 87 years old.
Left hand the back of the hand and arm two place's ulcer, remove state, Changji hospital admission, pneumonia, heart disease on inspection, left hand erysipelas ulcer is critically ill and can't be treated, advising it to leave hospital goes home. and family numbers of patients requires inventor's treatment of paying a home visit, seeing its patient is unable to leave the bed, painful groan, pure white unglazed, the kank of complexion, number flood, body temperature 38 degree, body of the tongue dim red, TAIGAN (sic) is thick, and is in full accord with state, Changji examination in hospital after diagnosing, controls pneumonia with antibiotic, the ulcer place applies medicine of the present invention, heals entirely through more than 20 days treatment ulcer.
3, name: Wu Shengying, sex, woman's age, 49 years old, Changji people from grains bureau.On October 5th, 2005 went to a doctor, and readme is failed to respond to any medical treatment everywhere because of right crus of diaphragm instep ulcer, and clean earlier and go up medicine of the present invention again, shared medicine four times, 15 days are complete.
4, name: Xu Lijuan, sex: woman, age: 58 years old, three teachers of level ground farm school, go to a doctor in December in 2004 end on the 25th, and readme was suffered from diabetes more than 20 year, lose the sight of both eyes, right legs and feet turn, too high because of the heating temperature, cause that right lower limb rots, ulcer area 50 * 50mm, dark and undisguised, go up medicine of the present invention through cleaning, 2 months complete.
5, name: Ma Derong, sex: the man, the age: 68 years old, May Day, the nine groups of people in farm suffered from diabetes 15 years, came my institute's treatment on November 8th, 2005, right lower limb bottom ulcer, area 30 * 25mm cleans on inspection and goes up medicine of the present invention, and tens days are promptly complete.
Six, clinical observation on the therapeutic effect result
Clinical efficacy the results are shown in Table 1.
The clinical observation on the therapeutic effect result of the test of table 1 medicine composite for curing diabetic ulcer of the present invention
Through 126 routine diabetic skin ulcer patient observed results are shown, medicine of the present invention all has significant curative effect for the diabetic skin ulcer patient, any untoward reaction is not seen in clinical observation, illustrates that pharmaceutical composition of the present invention is the safe and effective medicine of a kind of treatment diabetic skin ulcer.
Claims (5)
1. the pharmaceutical composition of an external curing diabetic skin ulcer is made up of following bulk drugs: Herba Portulacae 400-1200 part, Indigo Naturalis 100-600 part and Lasiosphaera Seu Calvatia 400-1200 part.
2. according to the pharmaceutical composition of claim 1, it is characterized in that the weight portion of each crude drug is: 600 parts of Herba Portulacaes, 300 parts of Indigo Naturaliss, 600 parts of Lasiosphaera Seu Calvatia.
3. the pharmaceutical composition of an external curing diabetic skin ulcer is made up of following bulk drugs: 20 parts of Herba Portulacae 400-1200 part, Indigo Naturalis 100-600 part, Lasiosphaera Seu Calvatia 400-1200 part and Borneolum Syntheticums.
4. a method for preparing the pharmaceutical composition of claim 1 comprises: take by weighing each raw material by following weight portion: Herba Portulacae 400-1200 part, Indigo Naturalis 100-600 part and Lasiosphaera Seu Calvatia 400-1200 part; With mix homogeneously behind the above-mentioned raw materials crushing screening, promptly.
5. any pharmaceutical composition of claim 1-3 is preparing the purposes for the treatment of in the diabetic skin ulcer medicine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2006100815328A CN101077360B (en) | 2006-05-26 | 2006-05-26 | Medicinal composition for treating sugar diabetes skin ulcer and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2006100815328A CN101077360B (en) | 2006-05-26 | 2006-05-26 | Medicinal composition for treating sugar diabetes skin ulcer and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101077360A CN101077360A (en) | 2007-11-28 |
| CN101077360B true CN101077360B (en) | 2010-09-08 |
Family
ID=38905131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2006100815328A Expired - Fee Related CN101077360B (en) | 2006-05-26 | 2006-05-26 | Medicinal composition for treating sugar diabetes skin ulcer and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101077360B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102406171B (en) * | 2011-11-28 | 2014-04-02 | 赣南医学院 | Health-care food for preventing and treating diabetes and hypertension and preparation method thereof |
| CN103212000B (en) * | 2012-03-06 | 2014-05-28 | 常美 | Preparation method of drug treating unhealed wound of diabetic patient |
-
2006
- 2006-05-26 CN CN2006100815328A patent/CN101077360B/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN101077360A (en) | 2007-11-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103585413A (en) | Medicine for external application for treating traumatic injuries | |
| CN102319397A (en) | Chinese medicinal decoction for treating chronic pelvic inflammatory disease with clystering method | |
| CN1247231C (en) | Health care medicine for enriching blood in puerperium and its preparation and uses | |
| CN101077360B (en) | Medicinal composition for treating sugar diabetes skin ulcer and preparation method thereof | |
| CN1325071C (en) | Antiphlogistic medicine | |
| CN105535495A (en) | Chinese medicinal composition for treating esophageal cancer by reinforcing vital essence and strengthening primordial qi and preparation method | |
| CN101991804B (en) | Externally applied medicament for treating stomach illness | |
| CN101036732A (en) | Chinese medicine preparation for esophagus cancer and its compounding process | |
| CN104055973B (en) | Treatment rheumatism bone disease, the Chinese medicinal liniment of arthralgia | |
| CN108392572B (en) | Plaster for removing stasis, promoting tissue regeneration, healing sore and relieving pain and preparation method and application thereof | |
| CN101933743B (en) | Traditional Chinese medical health pillow | |
| CN102940677B (en) | Medicine composition for treating diabetic foot | |
| CN1112003A (en) | Health sticker for lactation | |
| CN102218093B (en) | Externally applied traditional Chinese medicine for treating lumbar intervertebral disc herniation and preparation method thereof | |
| CN101229193A (en) | External Chinese patent medicine for treating skin ulceration and organism gangrene | |
| CN105106459A (en) | Traditional Chinese medicine gelling agent for treating superficial ulcer stage pressure sores and preparation method thereof | |
| CN104958613B (en) | Chinese medicine composition of malicious decomposed type decubital ulcer and preparation method thereof is accumulate in a kind for the treatment of | |
| CN104547591A (en) | Pharmaceutical composition for treating acute ankle sprain | |
| CN108295178B (en) | Traditional Chinese medicine composition and traditional Chinese medicine ointment for treating refractory wound and preparation method thereof | |
| CN101890076B (en) | Traditional Chinese medicine oral preparation for treating sores and ulcers | |
| CN103070994B (en) | Plaster for treating cervical and lumbar spondylosis | |
| CN103394009B (en) | Traditional Chinese medicine for treating trauma and diabetes foot ulcer and preparation method | |
| CN107582667A (en) | A kind of phthisical medicine of clinical treatment | |
| CN101711839B (en) | Medicine for treating diabetes | |
| CN101204554A (en) | Medicaments composite for stomach illness and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20100908 Termination date: 20110526 |