CN101076252A - Compositions of marine botanicals to provide nutrition to aging and environmentally damaged skin - Google Patents

Abstract

The present invention relates to novel methods and compositions comprising marine botanicals for treating aged, mature, nutritionally-compromised, or environmentally-damaged skin. These methods and compositions provide improvements in the skin's visual appearance, physiological functions, clinical properties, and biophysical properties.

Description

For aging and be subjected to the skin of environmental nuisance that the thalassophyte composition of nutrition is provided

The cross reference of related application

The application requires the U.S. Provisional Patent Application No.60/527 of submission on December 5th, 2003, the U.S. universal application No.10/751 that on January 5th, 568 and 2004 submitted to, and 684 interests, the full content of these two pieces of applications is incorporated herein by reference hereby.

Background of invention

A. invention field

Present invention relates in general to improve the Treatment and composition for of skin vision outward appearance.Specifically, the present invention relates to contain the compoistion and method of use of thalassophyte combination, it can improve the visual appearance of skin by improving for example humidity of skin, drying property, surface fine crack, wrinkle, fecundity and/or softness aspect.

B. background of invention

Along with the variation at age, long term exposure in hostile environment factor or malnutrition, the visual appearance of skin, physical characteristic and physiological function change in the mode of not expecting in the beauty treatment.The most remarkable and obvious variation comprises and forms microgroove and wrinkle, loss of elasticity, depression increase, fecundity forfeiture, color and luster uniformity or color and luster forfeiture, coarse superficial makings and mottled pigmentation.Not obvious but along with skin aging or stand long-term environmental hazard and measurable variation of occurring comprises that cell and organizational vitality generally reduce, the mistake of the reduction of the multiple-copy rate of cell, DBF minimizing, water content minimizing, structure and function accumulation, the change of common biochemical route normal regulating and the ability that skin itself is reinvented and repaired reduce.The many variations of skin on outward appearance and function are that the variation by the skin appearance cortex causes, cause and other variation is variation by lower floor's corium.

Can adopt several diverse ways to treat by aging, environmental factor, chemicals or the malnutritive damaged skin that causes.A kind of mode comprises the use particular agent, directly stimulates or suppresses selected biochemistry target.The example comprises and uses retinoids to stimulate the synthetic collagen of fibroblast and glycosaminoglycan (Schiltz, etc., 1986).Another kind of mode is to use can stimulate epidermis self to replace the reagent or the method for (being known as the process that epidermal cell upgrades) speed.The increase of epidermal cell turnover rate causes because of the very fast speed that epidermal basal cell duplicates usually, and can cause by multiple stimulation (as the direct stimulant of chemistry or physical damnification, the division of adverse environment conditioned disjunction basal cell).

Some examples of chemical damage comprise the interaction of allergic response or anallergic contact stimulus, extreme pH or cuticula and family expenses or industrial chemical or pollutant.Physical damnification can comprise that skin wearing and tearing, friction (that is, vola and heel) or the cuticula that causes because of physical property excoriation (for example, beauty mask) or banded peeling off remove.Directly or indirectly stimulate the reagent of basal cell division to comprise retinoids and barrier disrupting agent.For example, US patent 5,720,963 combination that discloses carboxylic acid, retinoids and cerebroside can cause cuticular chronic injury and cause the epidermis of structure deterioration skin and corium to be repaired.For example, US patent 6,495,126 use surfactant and combination of chelating agents, come stimulation of endogenous cuticula chymotrypsin (chymotryptic proteinase), thereby cause the loose of horn cell, causing skin to replace speed increases and chronic anti-aging benefit.Can cause that the adverse environment contact faster of skin renewal speed comprises UVA, UVB and the IR radiation and the associating cold and low relative humidity (promptly low dew point) of the sun.

The method of above-mentioned several increase cuticula renewal rates has various defectives, for example to significant stimulation, dermal toxicity or the low pH of skin.In addition, the major part of these methods comprises the chronic lesion to skin, sets up and repairs mechanism.For the treatment of existing great majority, will be for some time, be up to several weeks or several months, skin is upset during this period, and the symptom that occurs tolerance and stimulation afterwards can reduce and/or stop.

Summary of the invention

The present invention has solved defective of the prior art by the compoistion and method of use that can be used for the treatment of aging, ripe, nutritional deficiency and/or be subjected to environmental nuisance skin is provided.

In one aspect of the invention, described composition contain in the following composition at least a, two kinds or three kinds: algae extract, Crithmum maritimum (sea fennel) or fur pine algae (CodiumTomentosum) extract.Said composition can be by the form preparation of beauty treatment mixture.Said composition can also be included in the cosmetic carrier.Cosmetic carrier can comprise emulsion, white cream, washing lotion, solution, anhydrous base-material, gel or ointment.Emulsion can be emulsion oil-in-water or water-in-oil emulsion.Solution can be the aqueous solution or water-alcohol solution.Anhydrous base-material can be lipstick or powder.Composition can be included in aging products or the humidification product.Said composition also can be modulated into and use at least once in one day during use, twice, three times, four times, five times or more times.On the other hand, said composition can be that chemistry is compatible.

Algae extract can be further defined as green colored algae extract.Green colored algae extract can obtain from reef film (Monostroma).The reef film that can use in the present invention can comprise, for example, reef film (Monostroma nitidium), faro film (Monostromazostericola), bag reef film (Monostroma angicava), wide reef film (Monostromalatissimum), ball reef film (Monostroma bulbosum), arctic reef film (Monostromaarcticum), Monostroma areolatum, broken reef film (Monostroma fractum), Monostroma fuscum, Monostroma grevillei, Monostromaleptodermum, four row reef films (Monostroma quaternarium), faro film (Monostroma zostericola), point is planted reef film (Monostroma oxysperum) or thin reef film (Monostroma pulchrum).In another embodiment, algae extract can obtain from chlorella (Chlorella).Chlorella can be selected from powder nuclear chlorella (Chlorellapyrenoidosa), Chlorella regularis and chlorella vulgaris (Chlorellavulgaris).In specific embodiment, chlorella is included in the composition that contains CHLORELLINE .In another embodiment of the present invention, algae extract can obtain from sea lettuce (UlvaLactuca).Sea lettuce (Ulva Lactuca) can be included in and contain AOSAINE ^Composition in.Algae extract also can comprise reef film, chlorella and sea lettuce (Ulva Lactuca).In another embodiment, Crithmum maritimum can be included in the composition that contains OLEAPHYCOL .Fur pine algae extract can be included in the composition that contains CODIAVELANE .

One of the present invention concrete aspect in, composition contains the Crithmum maritimum of the algae extract of about 0.001%-about 5.0%, about 0.001%-about 5.0% and/or the fur pine algae extract of about 0.001%-about 5.0%.

Another embodiment of the present invention comprises the method for treatment or pre-anti-aging or damaged skin, comprise that local application contains the composition of at least a, two kinds and/or three kinds in the following composition: algae extract, Crithmum maritimum and fur pine algae extract, wherein using of said composition can be treated or pre-anti-aging or impaired skin.Said composition can be that chemistry is compatible.Said composition also can be with the amount local application of effective increase keratoderma renewal rate.Impaired skin can comprise the skin of nutritional deficiency or be subjected to the skin of environmental nuisance.Be subjected to the skin of environmental nuisance to comprise the skin that damages by ultraviolet ray, long-term solar radiation, environmental contaminants, chemicals, disease disease or smoking.Said composition can be further defined as cosmetic composition.Said composition can be included in the cosmetic carrier.The others of said composition comprise those that describe in the entire description.

A concrete aspect of the present invention comprises the composition that contains reef film, Crithmum maritimum, fur pine algae, chlorella and sea lettuce (Ulva Lactuca), and wherein said composition is by the form preparation of beauty treatment mixture.Crithmum maritimum can be included in the composition that contains OLEAPHYCOL ; Algae can be included in the composition that contains CODIAVELANE  the fur pine; Chlorella can be included in the composition that contains CHLORELLINE ; And/or sea lettuce (Ulva Lactuca) can be included in the composition that contains AOSAINE .

Another embodiment of the present invention comprises the method for treatment or pre-anti-aging or damaged skin, comprise that local application contains the composition of reef film, Crithmum maritimum, fur pine algae, chlorella and sea lettuce (UlvaLactuca), wherein using of said composition can be treated or pre-anti-aging or impaired skin.Crithmum maritimum can be included in the composition that contains OLEAPHYCOL ; Algae can be included in the composition that contains CODIAVELANE  the fur pine; Chlorella can be included in the composition that contains CHLORELLINE ; And/or sea lettuce (Ulva Lactuca) can be included in the composition that contains AOSAINE .

Any other saying of term " mixture " and " mixing " or these terms when using, comprises stirring, blend, dispersion, grinding, homogenate and other similar method in claims and/or specification.The component of disclosed composition or the mixing of composition can form solution.In other embodiments, composition can also undissolved soliquid form exist.

Any other saying of term " inhibition ", " minimizing " or " prevention " or these terms when using, comprises any measurable reduction or inhibition fully, so that reach desirable result in claims and/or specification.

In claims and/or specification, word " a " or " an " can be meant " a kind of " when " containing " coupling with term, but also can refer to " one or more ", the implication of " at least a " and " one or more ".

Any embodiment of being discussed in this specification can be implemented at any method of the present invention or composition, and vice versa.In addition, composition of the present invention and kit can be used to implement method of the present invention.

The application in the whole text in, the term " about " of use is the exponential quantity difference that comprises error and allow (these errors are measure in the used equipment of numerical value, the method inherent), the difference that perhaps exists between the research theme.

The term that uses in claims " or " be meant " and/or ", unless clearly indicate be meant or, or yes-no decision is to repel mutually, although disclosure support indication only be " perhaps " and " and/or " definition.

Word used in this specification and the claim " contains ", " having ", " comprising " or " containing " be inclusive or open, and do not get rid of part additional, that do not point out or method step.

Other purpose of the present invention, characteristics and advantage will become apparent from following detailed description.Yet, should be understood that and describe in detail and instantiation, when indicating specific embodiments of the present invention, only provide, pass through these to describe institute in detail conspicuous because various variations in essence of the present invention and scope and change are those skilled in the art in illustrational mode.

The description of exemplary

In the current society, aging, nutritional deficiency and be subjected to the skin of environment-infringement to influence a lot of people.Microgroove, wrinkle, loss of elasticity, depression increase, fecundity forfeiture, the forfeiture of color and luster uniformity, rough surface texture and mottled pigmentation only are some examples of damaged skin effect.In the past to the treatment damaged skin trial had various defectives, from the skin irriate to dermal toxicity.The a kind of of material that the present invention is to use retinoids compound or other to be used for the treatment of aging or environment damaged skin at present effectively substitutes.

The invention discloses the new method and the composition of treatment damaged skin.Disclosed method and composition provide such treatment in this specification, and this treatment can be by outward appearance, physiological function, clinical characteristics and the biophysics characteristic that provides nutrition to improve skin for skin.Nutrition can be vitamin, mineral matter, wetting agent and/or amino acid whose form.These and other aspect of the present invention is described hereinafter in more detail.

A. thalassophyte

Composition of the present invention can comprise, for example, and at least a or any combination in following compound and/or the extract: reef film, Crithmum maritimum, fur pine algae, chlorella and sea lettuce (UlvaLactuca).In specific embodiment, Crithmum maritimum is included in the composition that contains OLEAPHYCOL .Algae can be included in the composition that contains CODIAVELANE  the fur pine.Chlorella can be included in the composition that contains CHLORELLINE .Sea lettuce (Ulva Lactuca) can be included in the composition that contains AOSAINE .

1. reef film

The reef film is a kind of known green colored algae that can stimulate fibroblasts proliferation and increase the generation of extracellular matrix proteins.The reef film belongs to numerous species, comprises for example reef film (Monostromanitidium), faro film (Monostroma zostericola), bag reef film (Monostromaangicava), wide reef film (Monostroma latissimum), ball reef film (Monostromabulbosum), arctic reef film (Monostroma arcticum), Monostromaareolatum, broken reef film (Monostroma fractum), Monostroma fuscum, Monostroma grevillei, Monostroma leptodermum, four row reef films (Monostroma quaternarium), faro film (Monostroma zostericola), point is planted reef film (Monostroma oxysperum) and thin reef film (Monostromapulchrum).These and other kind of reef film can consider to be used for the present invention.

The reef film can also can be used as extract and buy in the outdoor growth of temperate zones.Air-dry reef film product has for example following composition: 16.9% moisture; 16.6% protein; 1.0% lipid; 47.5% carbohydrate; 5.6% fiber; With 12.4% ash content.Carbohydrate comprises polysaccharide, wherein comprises about 60% L-rhamnose and uronic acid, D-wood sugar, D-glucose, D-mannose etc.There are (United States Patent (USP) 4,758,283) in the major part of carbohydrate with the form of sulfuric acid rhamnosan (rhamnansulfate).

2.OLEAPHYCOL

OLEAPHYCOL  can provide lubricious sensation and have the benefit of antioxidant to skin.It contains extra large production of sperm oil field material and vitamin C.OLEAPHYCOL  can buy from various sources, for example comprises Presperse, Inc. (www.presperse.com).Various forms of OLEAPHYCOL  comprise for example OLEAPHYCOL-CM , OLEAPHYCOL-FV  and OLEAPHYCOL-LD , all can consider to be used for the present invention.In specific embodiment, preferred OLEAPHYCOL-CM .Active component among the OLEAPHYCOL-CM  is crithmummaritimum, is also referred to as Crithmum maritimum (Foeniculum vulgaris).

Crithmum maritimum contains anti-inflammatory and skin is had the composition of the effect of tightening.The elasticity that it can be used for strengthening flesh tension force and increases skin.Three kinds of bioactive ingredients: falcarinol (panaxynol), falcarindiol and hreims (Winsauer-Burkett, 2001) from Crithmum maritimum, have been identified.

3.CODIAVELANE

CODIAVELANE  comprises CODIAVELANE-BG , can be used for keeping the water balance of epidermis and provides moisture for skin.It can be available from for example Presperse, Inc..CODIAVELANE  contains propane diols, water and fur pine algae extract.Other composition comprises protein, glucuronic acid and methyl p-hydroxybenzoate.CODIAVELANE-BG  contains butanediol, water and fur pine algae extract.

Fur pine algae perhaps is called algae extract, makes the moisture normalization and the balance of skin by oligo-element and the enhancing surface hydration that replenishes life.Algae is to contain chlorophyllous organism, comprises the variety classes of kind more than 20,000.In cosmetics, algae is used as thickener, water-binding agent and antioxidant.The algae of other form as pelvetia silquosa (Irish moss) and carrageenan, contains protein, vitamin A, sugar, starch, vitamin B1, iron, sodium, phosphorus, magnesium, copper and calcium.These all can be used as emollient or the antioxidant composition (Ruperez etc., 2002) as skin nursing.

4.CHLORELLINE

CHLORELLINE  contains vitamin, mineral matter and amino acid.It can be skin (comprising aging or impaired skin) nutrient is provided.CHLORELLINE  can be available from RitaCorporation (www.ritacorp.com).A kind of active component among the CHLORELLINE  is a chlorella.

Chlorella is that monoplast green alga belongs to.Kind comprises powder nuclear chlorella, Chlorellaregularis and chlorella vulgaris, and all these can consider to be used for the present invention.It can be cultivated, results, purifying and be processed into powder, tablet and other form.It has anti-oxidation characteristics and can provide nutrient for skin (comprising aging or impaired skin).Chlorella contains chlorophyll A, chlorophyll B, vitamin A, B1, B2, B6, B12, C and E, beta carotene, potassium, sodium, magnesium, iron, calcium and 19 seed amino acids, comprises 8 kinds of whole essential amino acids.Other composition comprises vitamin h, inositol, chlorella growth factor (CGF), Chlorellan, dextran sulfate, fiber, DNA, RNA, enzyme, inositol, phosphorus, protein, thioester (sulfolipid) and folic acid.

5.AOSAINE

AOSAINE  can be used for preventing collagen and elastin laminin degraded, thereby helps to prevent wrinkle and skin aging.It can be available from for example Presperse, Inc..AOSAINE  can make the cell respiration optimization, and the generation of collagen in the chafe.It can also increase protein synthesis and cell proliferation.It contains many amino acid, comprises lysine, histidine, arginine, aspartic acid, proline, glycine, serine, glutamic acid, alanine, threonine, tyrosine, isoleucine, leucine and phenyl alanine.AOSAINE  is the hydrolysate of Sargassum protein matter in the algae sea lettuce (Ulva Lactuca).

Sea lettuce (Ulva Lactuca) extract has strong permeability, but fast Absorption in skin, thereby improve blood circulation, strengthen metabolism and discharge subcutaneous fat.It can also suppress the activity of elastoser, protected protein fiber, collagen and elastoser.Sea lettuce (UlvaLactuca) can promote the propagation of the vigor and the cell of skin, thereby prevents that epidermis is aging.In addition, sea lettuce (Ulva Lactuca) is also facilitated the generation of the enzymatic reaction of decomposition or fat metabolism.

6. the source of specific compound and extract

Active component in included particular compound, extract and these compounds and the extract of the present invention can obtain by any way well known by persons skilled in the art.For example, compound, extract and active component can separate by the source that obtains this compounds or extract.Described compound, extract or active component can come purifying by any technology well known by persons skilled in the art.This purification technique comprises for example polyacrylamide gel electrophoresis, high performance liquid chromatography (HPLC), gel chromatography or molecular sieve chromatography and affinity chromatography.

In addition, the active component in described compound, extract and these compounds and the extract can obtain by chemosynthesis or by the reorganization approach that uses routine techniques.For example, can commercially available various automatic polypeptide synthesizers and can use in accordance with known methods.Referring to for example Stewart and Young, (1969); Tam etc., (1983); Merrifield, (1986); With Barany and Merrifield (1979), Houghten (1985).As for the reorganization approach, the example is included in the nucleotide sequence of expressing encoded peptide or polypeptide in external translation system or the living cells.

7. equivalent (equivalents)

Can in the compositions and methods of the invention, use with the known and unknown equivalent of active component equivalence in particular compound, extract and this compounds and the extract discussed in the whole text in this specification.The substitute that equivalent can be used as particular compound, extract and active component uses.Equivalent can also be added in the method and composition of the present invention.For instance, the equivalent of reef film, Crithmum maritimum, fur pine algae, chlorella and/or sea lettuce (Ulva Lactuca) can be used in disclosed method and the composition in this manual.

Those skilled in the art needn't pass through undo experimentation, just can be familiar with and definite specific compound, extract and these compounds and extract in the acceptable known and unknown equivalent of active component.

B. composition of the present invention

1. the concentration of thalassophyte extract

Those of ordinary skill can recognize composition of the present invention can comprise any amount of thalassophyte extract or derivatives thereof combination.The concentration that also should consider thalassophyte extract of the present invention can change.In some non-limiting embodiments, the present composition can contain in final form, for example, at least about 0.0001%, 0.0002%, 0.0003%, 0.0004%, 0.0005%, 0.0006%, 0.0007%, 0.0008%, 0.0009%, 0.0010%, 0.0011%, 0.0012%, 0.0013%, 0.0014%, 0.0015%, 0.0016%, 0.0017%, 0.0018%, 0.0019%, 0.0020%, 0.0021%, 0.0022%, 0.0023%, 0.0024%, 0.0025%, 0.0026%, 0.0027%, 0.0028%, 0.0029%, 0.0030%, 0.0031%, 0.0032%, 0.0033%, 0.0034%, 0.0035%, 0.0036%, 0.0037%, 0.0038%, 0.0039%, 0.0040%, 0.0041%, 0.0042%, 0.0043%, 0.0044%, 0.0045%, 0.0046%, 0.0047%, 0.0048%, 0.0049%, 0.0050%, 0.0051%, 0.0052%, 0.0053%, 0.0054%, 0.0055%, 0.0056%, 0.0057%, 0.0058%, 0.0059%, 0.0060%, 0.0061%, 0.0062%, 0.0063%, 0.0064%, 0.0065%, 0.0066%, 0.0067%, 0.0068%, 0.0069%, 0.0070%, 0.0071%, 0.0072%, 0.0073%, 0.0074%, 0.0075%, 0.0076%, 0.0077%, 0.0078%, 0.0079%, 0.0080%, 0.0081%, 0.0082%, 0.0083%, 0.0084%, 0.0085%, 0.0086%, 0.0087%, 0.0088%, 0.0089%, 0.0090%, 0.0091%, 0.0092%, 0.0093%, 0.0094%, 0.0095%, 0.0096%, 0.0097%, 0.0098%, 0.0099%, 0.0100%, 0.0200%, 0.0250%, 0.0275%, 0.0300%, 0.0325%, 0.0350%, 0.0375%, 0.0400%, 0.0425%, 0.0450%, 0.0475%, 0.0500%, 0.0525%, 0.0550%, 0.0575%, 0.0600%, 0.0625%, 0.0650%, 0.0675%, 0.0700%, 0.0725%, 0.0750%, 0.0775%, 0.0800%, 0.0825%, 0.0850%, 0.0875%, 0.0900%, 0.0925%, 0.0950%, 0.0975%, 0.1000%, 0.1250%, 0.1500%, 0.1750%, 0.2000%, 0.2250%, 0.2500%, 0.2750%, 0.3000%, 0.3250%, 0.3500%, 0.3750%, 0.4000%, 0.4250%, 0.4500%, 0.4750%, 0.5000%, 0.5250%, 0.0550%, 0.5750%, 0.6000%, 0.6250%, 0.6500%, 0.6750%, 0.7000%, 0.7250%, 0.7500%, 0.7750%, 0.8000%, 0.8250%, 0.8500%, 0.8750%, 0.9000%, 0.9250%, 0.9500%, 0.9750%, 1.0%, 1.1%, 1.2%, 1.3%, 1.4%, 1.5%, 1.6%, 1.7%, 1.8%, 1.9%, 2.0%, 2.1%, 2.2%, 2.3%, 2.4%, 2.5%, 2.6%, 2.7%, 2.8%, 2.9%, 3.0%, 3.1%, 3.2%, 3.3%, 3.4%, 3.5%, 3.6%, 3.7%, 3.8%, 3.9%, 4.0%, 4.1%, 4.2%, 4.3%, 4.4%, 4.5%, 4.6%, 4.7%, 4.8%, 4.9%, 5.0%, 5.1%, 5.2%, 5.3%, 5.4%, 5.5%, 5.6%, 5.7%, 5.8%, 5.9%, 6.0%, 6.1%, 6.2%, 6.3%, 6.4%, 6.5%, 6.6%, 6.7%, 6.8%, 6.9%, 7.0%, 7.1%, 7.2%, 7.3%, 7.4%, 7.5%, 7.6%, 7.7%, 7.8%, 7.9%, 8.0%, 8.1%, 8.2%, 8.3%, 8.4%, 8.5%, 8.6%, 8.7%, 8.8%, 8.9%, 9.0%, 9.1%, 9.2%, 9.3%, 9.4%, 9.5%, 9.6%, 9.7%, 9.8%, 9.9%, 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%, 19%, 20%, 21%, 22%, 23%, 24%, 25%, 26%, 27%, 28%, 29%, 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, 95%, or 99% or more at least a thalassophyte extract, with can be from any scope that wherein derives.The concentration that those of ordinary skill in the art can understand plant extracts in the present composition can change according to adding, replacement and/or the subduction of other plant extracts and the acceptable substitute of these extracts.

Composition disclosed in this invention also can contain various antioxidants, so that block the oxidation of one or more components.In addition, by preservative can prophylaxis of microbial influence, described preservative for example is various antibacteriums and antifungal agent, includes but not limited to that p-hydroxybenzoate is (for example, methyl p-hydroxybenzoate, propylparaben), methaform, phenol, sorbic acid, thimerosal or its combination.

2. cosmetic carrier

Composition of the present invention all is effective in all types of cosmetic carrier.The non-limiting example of suitable cosmetic carrier comprises emulsion, frost cream, washing lotion, solution (moisture and water-alcohol), anhydrous base-material (as, lipstick and powder), gel and ointment, perhaps by other method or aforesaid any combination, as those skilled in the art (Remington ' s, 1990) that can know.Version and other suitable carriers will become apparent to those skilled in the art that and be suitable for using in the present invention.

In preferred embodiments, cosmetic carrier is selected from emulsion oil-in-water, and water-alcohol solution or the bag in anhydrous system are by pearl.With regard to emulsion oil-in-water, this emulsion and composition and preparation method be well known in the art.Yet, importantly select the concentration and the combination of compound and extract, make that this combination is that chemistry is compatible, and do not form the compound that will from finished product, be precipitated out.

3. beautification product

Composition of the present invention can also be used for a lot of beautification products, includes but not limited to moisturizing cream cream, beneficial skin frost cream and washing lotion, gel, ointment, foundation cream, late frost, lipstick, cleaning agent, toner, facial mask and/or color cosmetics.The composition first-selection is used for aging products, is used for facial and other body part, the most particularly stays the product (leave-onproduct) on the skin.

4. other compound and the reagent that can use with the present composition

Composition of the present invention can contain other beneficial agent and compound, for example acute or chronic humidizer (comprising for example humectant, occludent and the reagent that influences the natural humidification mechanism of skin), antioxidant, the sun-screening agent with UVA and/or UVB protective action, skin whitener are (for example, quinhydrones), emollient, counter-stimulus, vitamin, trace metal, antimicrobial, plant extracts, aromatic and/or dyestuff and coloring components.

The i humidizer

The non-limiting example of the humidizer that can use in the present composition comprises amino acid, chondroitin sulfate, diglycerol, antierythrite, fructose, glucose, glycerine, polyglycerine, dihydroxylic alcohols, 1,2, the 6-hexanetriol, honey, hyaluronic acid, hydrogenated honey, hydrogenated starch hydrolysate, inositol, lactitol, maltitol, maltose, mannitol, the natural humidification factor, PEG-15 butanediol, polyglycereol sorbierite, 2-pyrrolidone-5-carboxylic acid's salt, potassium PCA, propane diols, Sodium Glucuronate, sodium PCA, sorbierite, sucrose, trehalose, urea and xylitol.

Other example comprises acetylated lanolin; acetulan; acrylate/acrylic acid C10-30 alkyl ester cross-linked polymer; acrylate copolymer; alanine; marine algae extract; aloe barbadensis Miller (aloe barbadensis); the aloe barbadensis Miller extract; barbados aloe gel; marsh mallow (althea officinalis) extract; Dry Flo PC; aluminum stearate; apricot (prunus armeniaca) benevolence oil; arginine; the arginine aspartic acid; Arnica (arnica montana) extract; ascorbic acid; ascorbyl palmitate; aspartic acid; avocado (persea gratissima) oil; barium sulfate; the gas barrier sphingolipid; butanols; beeswax; tadenan; cupreol; BHT; birch (betula alba) bark extract; Common Borage (borago officinalis) extract; 2-bromo-2-nitro the third-1; the 3-glycol; butcher's broom (ruscus aculeatus) extract; butanediol; marigold (calendula officinalis) extract; marigold (calendula officinalis) oil; little candle tree (euphorbiacerifera) wax; rapeseed oil; caprylic/capric triglyceride; cardamom (elettariacardamomum) oil; babassu (copernicia cerifera) wax; carrageenan (chondrus crispus); carrot (daucus carota sativa) oil; castor-oil plant (ricinus communis) oil; ceramide; ceresine; spermaceti/Brij-721-5; spermaceti/Brij-721-12; spermaceti/Brij-721-20; sad spermaceti/stearyl; cetyl APEO-20; cetyl APEO-24; acetate spermaceti alcohol ester; sad spermaceti alcohol ester; cetin; yellow chamomile (anthemis nobilis) oil; cholesterol; cholesterol ester; Cholesteryl hydroxystearate; citric acid; Salvia scalarea (salvia sclarea) oil; cocoa (theobroma cacao) fat; lauric alcohol caprylic/capric ester; coconut (cocos nucifera) oil; collagen; collagen amino acid; corn (zea mays) oil; fatty acid; decyl oleate; dextrin; diazolidinyl urea; dimethicone copolyol; dimethiconol; dioctyl adipate; dioctyl succinate; dipentaerythritol six caprylates/six decylates; the DMDM hydantoins; DNA; antierythrite; ethoxydiglycol; ethyl linoleate; blue gum (eucalyptus globulus) oil; oenothera erythrosepala (oenotherabiennis) oil; fatty acid; tructose; gelatin; Bulgarian geranium (geraniummaculatum) oil; aminoglucose; the glucose glutamate; glutamic acid; glycerin polyoxyethylene ether-26; glycerine; glycerine; distearin; hydroxy stearic acid glyceride; glyceryl laurate ester; glyceryl linoleate; myristic acid glyceride; olein; tristerin; tristerin SE; glycine, ethylene glycol stearate, ethylene glycol stearate SE; glycosaminoglycan; grape (vitis vinifera) seed oil, fibert (corylus americana) benevolence oil, fibert (corylus avellana) benevolence oil; hexylene glycol; honey, hyaluronic acid, assorted safflower (carthamus tinctorius) oil; rilanit special; hydrogenation cocounut oil glyceride, hydrogenated coconut oil, hydrogenated lanolin; hydrolecithin; hydrogenated palm glyceride, hydrogenated palm kernel oil, oil with hydrogenated soybean; h-tallow glyceride; hydrogenated vegetable oil, hydrolytic collagen, elastin hydrolysis; the hydrolysis glycosaminoglycan; hydrolysis of keratin, hydrolytic soya bean protein, hydroxylated lanolin; hydroxyproline; imidazoline urea, carbamic acid iodine propine butyl ester, Standamul 7061; the stearyl Standamul 7061; Isodecyl oleate, isostearic acid isopropyl ester, isopropyl lanolate; isopropyl myristate; isopropyl palmitate, isopropyl stearate, isostearoyl amine DEA; isostearic acid; the different stearyl ester of lactic acid, the different stearyl ester of neopentanoic acid, jasmine (jasminumofficinale) oil; Jojoba wood (buxus chinensis) oil; sea grass, candlenut tree (aleurites moluccana) benevolence oil, lactamide MEA; lanolin alcohol APEO-16; lanolin alcohol APEO-10 acetic acid esters, lanolin, lanoceric acid; lanolin alcohol; lanolin oil, lanolin wax, lavender (lavandula angustifolia) oil; lecithin; lemon (citrus medica limonum) oil, linoleic acid, linolenic acid; macadamiaternifolia benevolence oil; dolomol, magnesium sulfate, maltitol; german chamomile (chamomillarecutita) oil; Glucate SS, methyl silicane alcohol PCA, microwax; mineral oil; ermine oil, Mortierella (mortierella oil) oil, Tetradecyl lactate; myristyl myristate; the propionic acid myristin, neopentyl glycol dicaprylate/dicaprate, octyldodecanol; nutmeg octyl group dodecyl ester; octyl group dodecyl stearyl stearate, octyl hydroxystearate, octyl palmitate; octyl salicylate; octyl stearate, oleic acid, olive (olea europaea) oil; orange (citrus aurantium dulcis) oil; palm (elaeisguineensis) oil, palmitic acid, pantethine; panthenol; the panthenyl ethyl ether, paraffin, PCA; peach (prunus persica) benevolence oil; peanut (arachis hypogaea) oil, PEG-8 C12-18 ester, PEG-15 coco amine; the PEG-150 distearate; the PEG-60 iso stearic acid of glycerine ester, PEG-5 stearine, PEG-30 stearine; the PEG-7 rilanit special; the PEG-40 rilanit special, PEG-60 rilanit special, PEG-20 Glucate SS; the high oleate of PEG40 anhydro sorbitol; the PEG-5 sojasterol, PEG-10 sojasterol, PEG-2 stearate; the PEG-8 stearate; the PEG-20 stearate, PEG-32 stearate, PEG40 stearate; the PEG-50 stearate; the PEG-100 stearate, PEG-150 stearate, omega-pentadecanolide; peppermint (menthapiperita) oil; vaseline, phospholipid, poly-aminosugar condensation product; polyglycereol-3-diisopstearate; polyquaternium-24, polysorbate 20, polysorbate 40; polysorbate 60; polysorbate 80, polysorbate 85, potassium myristate; potassium palmitate; potassium sorbate, potassium stearate, propane diols; propane diols dicaprylate/dicaprate; the propane diols dicaprylate, propylene glycol dipelargonate, propane diols laurate; propylene glycol stearate; propylene glycol stearate SE, PVP, pyridoxine dipalmitate; quaternium-15; quaternium-18 hectorite, quaternium-22, retinol; retinol palmitate; rice (oryza sativa) oil extracted from rice husks, RNA, rosemary, (rosmarinus officinalis) oil; attar of rose; safflower (carthamus tinctorius) oil, Salvia japonica (salviaofficinalis) oil, salicylic acid; santal (santalum album) oil; serine, haemocyanin, sesame (sesamum indicum) oil; sher butter (butyrospermum parkii); the silk powder, sodium chondroitin sulfate, DNA sodium Sodium Hyaluronate; sodium lactate; sodium palmitate, sodium PCA, polyglutamic acid sodium; odium stearate; soluble collagen, sorbic acid, sorbitan laurate; sorbitan oleate; sorbitan palmitate, Arlacel-83, sorbitan monostearate; sorbierite; soybean (glycine soja) oil, sphingolipid, saualane; squalene; stearmide MEA-stearate, stearic acid, stearoxy dimethicone; stearoxyl trimethyl silane; stearyl alcohol, stearyl glycyrrhetinate, stearyl heptanoate; stearyl stearate; sunflower (helianthus annuus) seed oil, dessert almond (prunus amygdalus dulcis) oil, synthetic bees wax; vitamin e; tocopherol acetate, Vitamin E linoleate, tribehenin; neopentanoic acid tridecyl ester; stearic acid tridecyl ester, triethanolamine, glyceryl tristearate; urea; vegetable oil, water, wax; wheat (triticumvulgare) embryo oil, and clothing orchid (cananga odorata) oil.

The ii antioxidant

The non-limiting example of the antioxidant that can use in the present composition comprises acetylcysteine, ascorbic acid, the ascorbic acid polypeptide, the ascorbyl dipalmitate, ascorbyl methyl silicane alcohol pectate, the ascorbyl palmitate, the ascorbyl stearate, BHA, BHT, tertiary butylated hydroquinone, cysteine, cysteine HCI, diamyl quinhydrones, two-tertiary butylated hydroquinone, the double hexadecyl thiodipropionate, two oil base tocopherol methyl silanols, ascorbic acid sulfuric acid disodium, the distearyl thiodipropionate, the double tridecyl thiodipropionate, lauryl gallate, erythronic acid (erythorbic acid), the ester of ascorbic acid, ferulic acid ethyl ester, forulic acid, gallate, quinhydrones, thioglycol acid isooctyl acrylate, kojic acid, Magnesium ascorbate, magnesium ascorbyl phosphate, methyl silicane alcohol acid ascorbyl ester, natural plant antioxidant is as green tea or grape seed extract, nordihydroguaiaretic acid, octyl gallate, the acid of phenyl thioglycol, ascorbic acid vitamin e potassium phosphate, potassium sulfite, n-propyl gallate, quinone, Rosmarinic acid (rosmarinic acid), sodium ascorbate, sodium hydrogensulfite, erythronic acid sodium (sodium erythorbate), sodium pyrosulfite, sodium sulphite, superoxide dismutase, thioglycol acid sodium, sorbierite furfural, thiodiglycol, the thiodiglycol acid amides, thiodiglycolic acid, thioglycol acid, thiolactic acid, thiosalicylic acid, tocophereth-5, tocophereth-10, tocophereth-12, tocophereth-18, tocophereth-50, vitamin e, PGS, tocopherol acetate, Vitamin E linoleate, tocopheryl nicotinate, tocopherol succinate, and three (nonyl phenyl) phosphite ester.

Iii has the compound of ultraviolet radiation absorption characteristic

The non-limiting example of the compound with ultraviolet radiation absorption characteristic that can use in the present composition comprises titanium dioxide, zinc oxide, benzophenone, benzophenone-1, benzophenone-2, benzophenone-3, benzophenone-4, benzophenone-5, benzophenone-6, benzophenone-7, benzophenone-8, Benzophenone 9, benzophenone-10, benzophenone-11, benzophenone-12, benzyl salicylate, butyl PABA, cinnamate derivative, Cinoxate, DEA-Methoxycinnamate, cinnamic acid diisopropyl methyl esters, ethyl dihydroxypropyl PABA, diisopropyl cinnamic acid ethyl ester, methoxy cinnamic acid ethyl ester, ethyl PABA, the urocanic acid ethyl ester, glycerol caprylate dimethoxy-cinnamic acid ester, glycerine PABA, glycol salicylate, heliophan, right-methoxy cinnamic acid isopentyl ester, PABA, PABA ester, Parsol 1789 and salicylic acid isopropyl benzyl ester.

Other compound of iv and beneficial agent

Other compound that can use in the present composition and the non-limiting example of reagent comprise skin whitener (for example, kojic acid, quinhydrones, ascorbic acid and derivative, retinoids and derivative thereof, and vitamin PP), emollient (for example, ester and fatty acid), vitamin (D for example, E, A, K and C), trace metal (for example, zinc, calcium and selenium), counter-stimulus (for example, steroid and non--steroid antiinflammatory), antimicrobial (for example triclosan), plant extracts (for example, aloe, yellow chamomile, Fructus Cucumidis sativi extract, ginkgo, genseng and rosemary), dyestuff and coloring components (for example, D﹠amp; No. four indigo plants of C, D﹠amp; No. five, C is green, D﹠amp; The C orange, D﹠amp; No. 17, C is red, D﹠amp; No. 33, C is red, D﹠amp; No. two purples of C, D﹠amp; No. 10 Huangs of C, D﹠amp; No. 11 Huangs of C and DEA-cetyl phosphate), preservative (for example BHA), emollient (that is, organic ester, fatty acid, lanolin and derivative thereof, plant and animal oil ﹠ fat, and diglyceride and triglycerides), antimicrobial is (for example, triclosan and ethanol), and aromatic (natural with artificial).

Embodiment

Following examples are used for showing embodiment preferred of the present invention.The disclosed technology in following examples of it will be appreciated by those skilled in the art that is represented the technology that plays fine effect in practice of the present invention found by the inventor, can think to have constituted the preference pattern of its enforcement thus.Yet, one skilled in the art will appreciate that according to content disclosed in this invention, under the prerequisite that does not deviate from the spirit and scope of the invention, on the basis of disclosed specific embodiments, can make a lot of variations and still obtain same or analogous effect.

Embodiment 1

Chronic anti-aging effect research

Material and method: carry out following research and long-term visible and measurable anti-aging benefit is provided whether can for people's face with the living composition in sea (non-limiting example of plant mixture of the present invention) that mensuration contains 5.0%CODIAVELANE , 1.0%AOSAINE , 2.0% reef film, 5.0%OLEAPHYCOL-CM  and 3.0%CHLORELLINE .Carrier A (table 1) is as tester.20 members of panel of expert sooner or later use composition at their face, twice of every day every day.

Table 1: carrier A *

Phase	Composition	In the % prescription
			A	Water	58.4
A	Glycerin polyoxyethylene ether-26	5.0
			A	Hispagel	5.0
A	The EDTA disodium	0.05
			A	Carbopol 940，2％	15.0
B	Lecinol S-10	1.0
			C	Cosmowax J	1.25
C	Finsolve TN	6.0
			C	Dimethyl silicone polymer	0.5
C	Isooctadecanol	1.25
			C	Cetanol	0.7
C	Silica	0.35
			D	Triethanolamine, 99%	1.16
D	Water	1.60
			E	Germaben II	1.0
F	The PCA sodium salt	0.11
			F	Prodew 400	0.7
F	Tocopherol acetate	0.1
			F	Phosphatide EFA	0.82

* make the process of carrier A: add among the A composition under the room temperature in order to container, mix after each the interpolation.Begin to be heated to 75 ℃.Under 50 ℃, add B.Under 75 ℃, add c in order, mix after each the interpolation.Along with the mixture cooling, 65 ℃ are added D down.Under 45 ℃, add E and F.

Eight monitor the member's of panel of expert skin when all around after research beginning (promptly before treatment), treatment and after the treatment.Their face and humidity, drying property, surface fine crack, crow's foot, fecundity, softness and the clarity of neck are estimated.Qualification result in the table 2 adopts following method to obtain.Facial and neck humidity adopts impedance measurement to estimate, and it is the conductivity measurement that a kind of Nova of use Dermal Phase Meter carries out.Drying property, surface fine crack and softness are measured by the scoring expert, use standardized visual simulation grade, from 1 to 10.Skin softness using gases carrying electrodymamometer (Gas BearingElectrodynamometer) is measured.To the surface fine crack counting, the seriousness of streakline is used weighting to keep the score according to Packman-Gans method (1978) and is estimated.The standardized visual simulation grade of drying property use from 1 to 10 is estimated.Fecundity uses Hargensballistometer to estimate, and it is a kind of by wisp is fallen on the skin, and writes down its preceding two resilience peaks and come the device of evaluating skin elasticity and fecundity.Along with fecundity reduces, second peak compared less with first peak.Clarity uses Minolta Chromameter to estimate, and it measures the total light that reflects from skin, and compares with the amount of brown/sodium yellow with red.These measured values through mathematical analysis, are recorded the clarity of skin.Around after treatment and eight weeks crow's foot was estimated, this is to realize by the silicone duplicate of being made by the skin of individuality on the comparison base (negative effects).Duplicate is estimated by the computer generated image assay determination number of wrinkles and the degree of depth.

The result: as shown in table 2 and 3, find the research in 8 weeks during the skin condition parameter continue to improve.The composition that contains thalassophyte is better than the carrier A tester.Also find the improvement that continues for carrier A.This is the humidification composition in the carrier A prescription due to.

Table 2: the thalassophyte composition is to the influence of application on human skin

Benefit to skin	The improvement that % compares with baseline
					Carrier A		Carrier A+plant mixture
	4 weeks	8 weeks	4 weeks	8 weeks
					Cheek humidity	20.6	33.5	33.6	48.0
Neck humidity	27.9	36.5	35.3	49.9
					Fecundity	12.1	24.4	17.0	29.0
Softness/compliance	22.2	32.4	26.0	41.1
					Crow's foot	17.2	28.4	24.0	43.3
Clarity	4.8	8.5	5.8	11.3
					Surface fine crack	18.1	29.2	23.1	41.2
Drying property	32.7	51.0	36.4	58.6

Table 3: the member of panel of expert during 8 week treatments to thalassophyte

Self estimating of composition

Benefit to skin	% feels the member * of panel of expert that skin is greatly improved
							Carrier A			Thalassophyte in the carrier A
	Skin	2 weeks	4 weeks	8 weeks	2 weeks	4 weeks							8 weeks
Drying property							53.3	66.7	86.7	60.00	80.00	100.0
	Slickness	46.7	60.0	80.0	60.0	73.3							100.0
Microgroove and wrinkle							6.7	26.7	60.0	20.00	46.7	66.7
	Fecundity	6.7	46.7	66.7	20.00	60.0							80.0
Softness							33.3	46.7	73.3	53.3	60.0	86.7
	Healthy ruddy look	13.3	26.7	46.7	26.7	33.3							66.7
Elasticity							26.7	53.3	66.7	20.00	66.7	86.7
	Appearance is younger	13.3	46.7	73.3	20.0	60.0							86.7
Appearance is more healthy							20.0	46.7	80.00	26.7	60.00	86.7

* 15 members of panel of expert participate in research in each treatment unit.At use product 2,4 with after 8 weeks, the situation the when member of panel of expert gives its skin with the research beginning compares, and divides system to give a mark by 5-.The scoring scope from the parameter of estimating be poorer, poor slightly, do not change, improve a little and bigger improvement.Numeric representation is felt the member's of panel of expert the percentage of bigger improvement at described time point.The those of ordinary skill of beauty treatment fields can be understood the implication of the used term of table 3 left column.

Embodiment 2

Cuticula is recent studies on more

Material and method: use the renewal rate of following method assessor's skin epicuticle, it is directly produced by the activation of epidermis.Use plastic plate four sites of mark on forearm.Use Minolta Chromameter to measure the baseline registration (being listed in the b* value in the table 4) of color intensity.Airtight Hilltop cell (2cm diameter) is placed on these sites, and wherein cell is equipped with 0.05ml Mary Kay SUN ESSENTIALS  sunless solarization black wash (Sunless Tanning Lotion) product and dihydroxyacetone (DHA) (DHA).After 6 hours, remove patch, and after 18 hours, use colorimeter to measure color intensity once more.Δ b* numerical value in the table 4 calculates by the difference of registration and baseline.The member of panel of expert is applied to the prescription in the table 5 on the foxiness with evening in the morning during 10 days that follow the tracks of.After 4,7 and 10 days, repeat the colorimeter reading.Color and luster decline gradient is calculated with the percentage of color and luster forfeiture every day, and loses and measure conversion time (transit time) by being extrapolated to 100% color and luster.

The result: this result of study (table 4) shows with carrier B (table 5) to be compared, and the combination of Crithmum maritimum, reef film and CHLORELLINE  has increased the speed that cuticula self upgrades, and wherein carrier B is used to mix this three composition.This influence is concentration-dependence.The increase of cuticula renewal rate shows that Crithmum maritimum, reef film and the CHLORELLINE  in the composition can activate and/or the epidermis of chafe.

Table 4: Crithmum maritimum, reef film and CHLORELLINE  are to people's cuticula

The influence of renewal rate

The composition of test	Cuticula renewal rate (Δ b*/sky)	% compares the variation of cuticula renewal rate with untreated tester
			Untreated	0.590	--------
Carrier B (table 5)	0.632	7
			Carrier B+0.5% reef film+1.0%CHLORELLINE 	0.660	12
Carrier B+2.0% reef film+3.0%CHLORELLINE 	0.691	17

Table 5: carrier B *

Phase	Composition	In the % prescription
			A	Water	87.86
A	The EDTA disodium	0.10
			A	Forulic acid	0.01
A	Carbopol ETD 2020	0.30
			B	Butanediol	5.00
B	Methyl p-hydroxybenzoate	0.20
			C	The L-arginine	0.50
C	Water	5.00
			D	Triethanolamine, 99%	0.25
E	The DMDM hydantoins	0.20
			F	Vegetech Night Breeze	0.01
F	Sea Rocket extract	0.01
			F	The Elias mixture	0.05
F	The Crithmum maritimum extract	0.01
			G	Single ball PACE	0.50

* make the process of carrier B: adding ingredient B is to container in order under the room temperature, and each the interpolation afterwards mixes.Under the room temperature phase A is joined among the B.Add C, D, E and F under the room temperature in order, mix after each the interpolation.At room temperature slowly add G at last

**************

Content disclosed according to the present invention, open and claimed all compositions and/or method and/or device need not undo experimentation and just can make and implement in this specification.Though the compositions and methods of the invention are with the formal description of preferred embodiment, but under the prerequisite that does not deviate from notion of the present invention, essence and scope, can change to composition of the present invention and/or method and/or device with in the step of method or sequence of steps, this it will be apparent to those skilled in the art that.More specifically say, use that some all relevant reagent substitutes reagent as herein described aspect chemistry and physiology, can reach same or analogous effect equally.The similar alternative and improvement that all these it will be apparent to those skilled in the art that all is considered to belong to by within the determined essence of the present invention of claims, scope and the notion.

List of references

Specifically be incorporated herein by reference below with reference to document, they provide exemplary process or other detailed property to replenish to content as herein described.

US Patent 4,758,283

US Patent 5,720,963

US Patent 6,495,126

Barany and Merrifield，In：The Peptides，Gross andMeienhofer(Eds.)，Academic Press，NY，1-284，1979.

Blumenthal etc., In:Herbal Medicine, Expanded Commission EMonographs, 1st Ed., Integrated Medicine Communications, Newton, MA, 2000.

Fang etc., Univ.of Cairo, Bull.Fac.Agric, 43 (1): 31-44,1992.

Houghten，Proc.Natl.Acad.Sci.USA，82(15)：5131-5135，1985.

Merrifield，Science，232(4748)：341-347，1986.

Packman-Gans method，J.Soc.Cosmetic Chem.29：70，1978

Packman-Gans，J.Soc.Cosmetic Chem.，29：70，1978.

Remington′s Pharmaceutical Sciences，18th Ed.MackPrinting Company，1990.

Ruperez etc., J.Agric.Food Chem., 50 (4): 840-845,2002.

Schiltz etc., J.Investigative Dermatology, 87:663-667,1986.

Stewart and Young，In：Solid Phase Peptide Synthesis，24-66，Freeman，San Francisco，1969.

Tam etc., J.Am.Chem.Soc., 105:6442,1983.

Winsauer-Burkett，Fennel，Alt MedDex，June 2001.

Claims (30)

1. composition wherein comprises at least two kinds in the following composition:

(a) algae extract;

(b) Crithmum maritimum; With

(c) fur pine algae (Codium Tomentosum) extract,

Wherein said composition is formulated into the beauty treatment mixture.

2. the composition of claim 1, wherein said composition is included in the cosmetic carrier.

3. the composition of claim 2, wherein said cosmetic carrier comprises emulsion, white cream, washing lotion, solution, anhydrous base-material, gel or ointment.

4. the composition of claim 3, wherein said emulsion is emulsion oil-in-water or water-in-oil emulsion.

5. the composition of claim 3, wherein said solution is the aqueous solution or water-alcohol solution.

6. the composition of claim 3, wherein anhydrous base-material is lipstick or powder.

7. the composition of claim 1, wherein said composition is included in aging products or the humidification product.

8. the composition of claim 1, said composition are suitable for using at least once in one day during use.

9. the composition of claim 1, wherein said composition is suitable for using at least twice in one day during use.

10. the composition of claim 1, wherein said algae extract is further defined as green colored algae (green flower algae) extract.

11. the composition of claim 10, wherein said green colored algae extract obtains from reef film (Monostroma).

12. the composition of claims 11, wherein the reef film is selected from reef film (Monostromanitidium), faro film (Monostroma zostericola), bag reef film (Monostromaangicava), wide reef film (Monostroma latissimum), ball reef film (Monostromabulbosum), arctic reef film (Monostroma arcticum), Monostroma areolatum, broken reef film (Monos troma fractum), Monostroma fuscum, Monostromagrevillei, Monostroma leptodermum, four row reef films (Monostromaquaternarium), faro film (Monostroma zostericola), point is planted among reef film (Monostroma oxysperum) and the thin reef film (Monostroma pulchrum).

13. the composition of claim 1, wherein algae extract obtains from chlorella (Chlorella).

14. the composition of claim 13, wherein this chlorella is selected from powder nuclear chlorella (Chlorella pyrenoidosa), Chlorella regularis and chlorella vulgaris (Chlorella vulgaris).

15. the composition of claims 13, wherein chlorella is included in the composition that contains CHLORELLINE .

16. the composition of claim 1, wherein algae extract obtains from sea lettuce (UlvaLactuca).

17. the composition of claims 16, wherein sea lettuce (Ulva Lactuca) is included in the composition that contains AOSAINE .

18. the composition of claim 1, wherein algae extract comprises reef film, chlorella and sea lettuce (Ulva Lactuca).

19. the composition of claim 1, wherein Crithmum maritimum is included in the composition that contains OLEAPHYCOL .

20. the composition of claim 1, wherein fur pine algae (Codium Tomentosum) extract is included in the composition that contains CODIAVELANE .

21. the composition of claim 1, wherein said composition comprises the algae extract of about 0.001%-about 5.0%.

22. the composition of claim 1, wherein said composition comprises the Crithmum maritimum of about 0.001%-about 5.0%.

23. the composition of claim 1, wherein said composition comprises the fur pine algae extract of about 0.001%-about 5.0%.

24. the composition of claim 1, wherein said composition is that chemistry is compatible.

25. the method for a treatment or pre-skin anti-aging or impaired, this method comprise local at least two kinds the composition that comprises in the following composition of using:

(a) algae extract;

(b) Crithmum maritimum; With

(c) fur pine algae (Codium Tomentosum) extract,

Wherein using of said composition can be treated or pre-skin anti-aging or impaired.

26. the method for claim 25, wherein said composition are that chemistry is compatible.

27. the method for claim 25, wherein said composition is with the amount local application of effective increase keratoderma renewal rate.

28. the method for claim 25, wherein said composition is contained in the cosmetics carrier.

29. the method for claim 25, wherein said composition are with one day at least once or used in one day at least twice.

30. a composition wherein comprises:

(a) reef film;

(b) Crithmum maritimum;

(c) fur pine algae;

(d) chlorella; With

(e) sea lettuce (Ulva Lactuca)

Wherein said composition is formulated into cosmetic complex.