CN101070927A - 相变型阀门及其制造方法 - Google Patents
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Abstract
提供一种相变型阀门,通过在通道的预定段注入相变材料并使该相变材料硬化,其中所硬化的相变材料通过热源融化,以打开通道。该阀门包括管状扩展区域,其具有的横截面积大于通道的横截面积,形成在相变材料所要硬化的段的两端。在精确的位置上形成相变型阀门,且由此,该阀门可以在所需的时间点上被精确地打开。
Description
技术领域
本发明涉及相变型阀门,可被热源融化,以打开被阻断的通道,以使得流体可以流过通道,以及涉及这种阀门的制造方法。
背景技术
在诸如血液测试这样的生化试验中,许多过程被执行,以获得所需的结果,例如,具有不同比重的血液成分要进行相分离,且所需成分的特性和形状通过注入试剂来改变。如果一个接一个地手动执行这一系列处理,则会花费很长时间,且只要血液被移动以执行另一处理时,很可能会有产生错误的成分被引入到被测血液中。因此,通常使用如图1所示的生化反应基片10,以使得可以在一处自动而迅速地一次执行一系列。
在基片10中,能使被测液体1和试剂2通过的通道13如此形成:被测液体1和试剂2以所需时间点流过通道13,以执行处理。例如,可如下地执行一简单顺序,在该顺序中,试剂与被测液体1的上层混合,而该上层为从出口12中出来的产物相分离的结果。也就是,被测液体1通过入口11注入,而马达14被驱动,以旋转基片10。随后,被测液体1由于离心力而相分离。由于被测液体1不应在相分离结束之前流过通道13,所以相变型阀门15a阻挡通道13,且随后,阀门15a在相分离完成时打开。相变型阀门15a通过使诸如蜡这样的憎水材料在通道13中的预定位置上硬化而获得,且由此,蜡被热能融化,且通道13打开。因此,当相分离完成且所需成分被收集到上层时,用激光二极管16将激光照射在相应的阀门15a上,以融化阀门15a。随后,通道13打开,且被测液体1中的上层液体沿通道13流动。此外,阻挡试剂2的阀门15b也被激光融化,且随后,被测液体1和试剂2互相混合,以形成产物,该产物通过出口12排放。通过控制器(未示出)自动地控制上述一系列过程,且由此,使用者所要作的仅仅是将被测液体1放入入口11中,且随后,起动设备的运转,以通过自动过程获得产物。
为了充分地执行自动处理过程,阀门15a和15b应精确地在所需的时间点打开,且由此,阀门15a和15b应确切地在设定位置上硬化,在该位置上制造出阀门15a和15b。也就是,通过使用从激光二极管16发出的激光束使阀门15a和15b融化,从而执行阀门15a和15b的打开,且由此从激光二极管16发出的激光束的会聚区域设置的略微大于阀门15a和15b的尺寸,且激光被自动地控制,以精确地照射在预定区域上。因此,如果阀门15a和15b被硬化在预定区域之外,或硬化得大于阀门15a和15b的预定尺寸,则即使照射了激光通道13也不会完全打开。
当通过注入蜡在通道13的相应位置上制造阀门15a和15b时,经常会发生上述问题。例如,如图2A所示,即使蜡15以形成阀门的张紧力来通过注入孔10a在L段处注入蜡15,蜡15也可能会如图2B所示那样偏向一侧(图2C为显示图2B的情况的照片),或可能会如图2D那样比所预期的伸展得较宽。为了解决上述问题,应在注入蜡15之后执行对蜡15的硬化位置的调整处理,而制造阀门的过程会变得复杂。
发明内容
本发明提供一种相变型阀门,且可以在所学位置精确的形成,而不必执行额外的处理,以及提供制造该阀门的方法。
根据本发明的一个方面,提供一种相变型阀门,包括:相变材料,在通道的预定位置上填充并硬化;和管状扩展区域,具有的横截面大于通道横截面,形成在相变材料硬化段处的两端。
根据本发明的另一方面,提供一种制造相变型阀门的方法,该方法包括:形成管状扩展区域,其横截面积大于通道的横截面积,位于通道中相变材料将要硬化的段的两端;以及在管状扩展区域之间的通道中注入相变材料并使该相变材料硬化。
管状扩展区域形成为至少具有方形端部、V形端部、U形端部或鸽尾形端部中的一种。相变材料是从蜡、凝胶和热塑材料构成的材料组中选择的一种。
附图说明
通过详细描述本发明的示例性实施例并参考附图,本发明的上述和其他特征及优点将更加显而易见,其中:
图1为具有传统相变型阀门的生化反应基片示意图;
图2A至2D为示出当使用图1的相变型阀门时通常会发生的一些问题的横截面示意图。
图3为具有根据本发明示例性实施例的相变阀门的生化反应基片的剖面透视图。
图4A为图3的相变型阀门的平面图;
图4B为图4A的相变型阀门的图像;和
图5A至5F为图3的相变型阀门的修改实例的视图。
具体实施方式
图3为生化反应基片100的剖面透视图,包括根据本发明实施例的相相变型阀门110。图4A为该相变阀门110的平面图,而图4B为相变型阀门110的图像。
通过使相变材料的蜡111硬化为通道120所需的一段来形成根据本实施例的相变型阀门110,且随后,如有必要蜡111可以通过注入激光这样的热源来融化,以打开通道120。然而,本实施例的相变型阀门110包括管状扩展区域130,该区域130具有的横截面积大于通道120的横截面积,形成在蜡111所要填充的空间的两端。管状扩展区域130形成在该空间的端部,以便将形成相变型阀门110的蜡111引入而不会脱离设定位置,并形成为具有确切的长度。也就是,当管状扩展区域130形成在蜡111所要填充的空间的端部时,当蜡111处于融化状态时,蜡111在通道中的流动受到管状扩展区域130的阻碍。这是因为,当蜡111到达管状扩展区域130时,通道的横截面积突然增加且空置的空间出现在蜡111的周围,该蜡111已经预先沿通道120的壁面流动了。由此,在这种状况下,融化的蜡111的端部由于表面张力而凝结,如图4A和4B所示,且随后,蜡111的流动停止。由此,蜡111不会脱离由管状扩展区域130所限定的空间的两端,并填充在边界之间的空间中,并经过一端时间后硬化。随后,蜡111精确地硬化在所需部位上,并形成相变型阀门110,且由此,相变型阀门110可以用激光精确地融化。
当制造了本实施例的相变型阀门110时,如图3所示,具有管状扩展区域130的通道120用压制工艺形成在基底101上,封盖102形成在通道120上,且随后,融化的蜡111通过注入孔103注入。随后,融化的蜡111在通道120中流动,并在管状扩展区域130处停止。此外,蜡111以上述状态硬化,以形成相变型阀门110。
因此,如果在实验中使用具有形成在确定位置上的相变型阀门110的生化反应基片100,则可以使用激光使相变型阀门110精确地在所需时间点上融化,以打开通道120。由此,可以精确地执行实验。
在本实施例中,管状扩展区域130形成为具有方形的端部,然而,管状扩展区域可以形成为如图5A和5B所示的U形端部(131),如图5C和5D所示的V形端部(132),或形成为具有如图5E和5F所示的鸽尾形端部133。如附图中所示,管状扩展区域可以对称地形成在通道两侧,或可以不对称地形成在通道的一侧。
此外,相变材料可以至少为蜡、凝胶和热塑树脂中的一种。
根据本发明的相变形阀门当相变材料在精确的位置上硬化的同时制造出,且由此,阀门可以在所需时间点上打开。
尽管已经参考本发明的示例性实施例对本发明作了具体的显示和描述,但本领域技术人员应理解,在不脱离由所附权利要求所限定的本发明的精神和范围内,可在形式和细节上作各种改变。
Claims (6)
1、一种相变型阀门,包括:
相变材料,在通道的预定段上填充并硬化;和
管状扩展区域,具有的横截面大于所述通道横截面,形成在所述相变材料硬化段处的两端。
2、根据权利要求1所述的相变型阀门,其中所述管状扩展区域形成为至少具有方形端部、V形端部、U形端部或鸽尾形端部中的一种。
3、根据权利要求1所述的相变型阀门,其中所述相变材料是从蜡、凝胶和热塑材料构成的材料组中选择的一种。
4、一种制造相变型阀门的方法,该方法包括:
形成管状扩展区域,其横截面积大于通道的横截面积,位于所述通道中相变材料将要硬化的段的两端;以及
在所述管状扩展区域之间的通道中注入所述相变材料并使该相变材料硬化。
5、根据权利要求4所述的方法,其中所述管状扩展区域至少形成为方形端部、V形端部、U形端部或鸽尾形端部中的一种。
6、根据权利要求4所述的方法,其中所述相变材料至少为蜡、凝胶和热塑材料构成的材料组中选择的一种。
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CN105465480A (zh) * | 2015-11-16 | 2016-04-06 | 中国科学院理化技术研究所 | 一种相变阀装置及其制备方法 |
CN107573704A (zh) * | 2017-09-27 | 2018-01-12 | 北京工业大学 | 一种基于导电复合材料和感应热驱动的相变微阀 |
CN109982731A (zh) * | 2016-10-03 | 2019-07-05 | 泰尔茂比司特公司 | 离心流体分离设备 |
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US8464760B2 (en) * | 2006-08-16 | 2013-06-18 | Samsung Electronic Co., Ltd. | Valve unit, reaction apparatus with the same, and method of forming valve in channel |
KR100955481B1 (ko) | 2008-05-14 | 2010-04-30 | 삼성전자주식회사 | 밸브 유닛, 이를 구비한 미세유동장치, 및 상기 밸브유닛의 제조방법 |
JP5446597B2 (ja) * | 2009-08-25 | 2014-03-19 | 藤倉化成株式会社 | 液体流路装置とその製造方法 |
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CN105465480A (zh) * | 2015-11-16 | 2016-04-06 | 中国科学院理化技术研究所 | 一种相变阀装置及其制备方法 |
CN105465480B (zh) * | 2015-11-16 | 2018-11-30 | 中国科学院理化技术研究所 | 一种相变阀装置及其制备方法 |
CN109982731A (zh) * | 2016-10-03 | 2019-07-05 | 泰尔茂比司特公司 | 离心流体分离设备 |
CN109982731B (zh) * | 2016-10-03 | 2022-08-19 | 泰尔茂比司特公司 | 离心流体分离设备 |
CN107573704A (zh) * | 2017-09-27 | 2018-01-12 | 北京工业大学 | 一种基于导电复合材料和感应热驱动的相变微阀 |
CN107573704B (zh) * | 2017-09-27 | 2019-07-05 | 北京工业大学 | 一种基于导电复合材料和感应热驱动的相变微阀 |
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US20070264628A1 (en) | 2007-11-15 |
EP1855038A3 (en) | 2008-02-20 |
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US7837948B2 (en) | 2010-11-23 |
JP4980106B2 (ja) | 2012-07-18 |
JP2007303674A (ja) | 2007-11-22 |
KR100738113B1 (ko) | 2007-07-12 |
EP1855038B1 (en) | 2013-07-10 |
CN101070927B (zh) | 2013-05-08 |
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