CN101057959B - Pharmaceutical composition for treating lumbar facet joint disorder syndrome and waist support - Google Patents
Pharmaceutical composition for treating lumbar facet joint disorder syndrome and waist support Download PDFInfo
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- CN101057959B CN101057959B CN2007100486522A CN200710048652A CN101057959B CN 101057959 B CN101057959 B CN 101057959B CN 2007100486522 A CN2007100486522 A CN 2007100486522A CN 200710048652 A CN200710048652 A CN 200710048652A CN 101057959 B CN101057959 B CN 101057959B
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- 208000011580 syndromic disease Diseases 0.000 title abstract description 16
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- 208000012659 Joint disease Diseases 0.000 title abstract 4
- 239000003814 drug Substances 0.000 claims abstract description 35
- 239000002994 raw material Substances 0.000 claims abstract description 17
- 238000010438 heat treatment Methods 0.000 claims abstract description 13
- 239000006247 magnetic powder Substances 0.000 claims description 5
- 235000003140 Panax quinquefolius Nutrition 0.000 claims description 4
- 240000005373 Panax quinquefolius Species 0.000 claims description 4
- 230000000694 effects Effects 0.000 abstract description 21
- 208000002193 Pain Diseases 0.000 abstract description 17
- 230000036407 pain Effects 0.000 abstract description 17
- 238000002653 magnetic therapy Methods 0.000 abstract description 8
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- 238000000015 thermotherapy Methods 0.000 abstract description 3
- 244000223760 Cinnamomum zeylanicum Species 0.000 abstract 1
- 235000006679 Mentha X verticillata Nutrition 0.000 abstract 1
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- 235000001636 Mentha x rotundifolia Nutrition 0.000 abstract 1
- 241000234314 Zingiber Species 0.000 abstract 1
- 235000006886 Zingiber officinale Nutrition 0.000 abstract 1
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- 235000008397 ginger Nutrition 0.000 abstract 1
- 230000009044 synergistic interaction Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
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- 208000008035 Back Pain Diseases 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Magnetic Treatment Devices (AREA)
Abstract
The invention relates to a pharmaceutical composition for treating lumbar facet joint disorder syndrome, belonging to the field of medicines. The active ingredients of the pharmaceutical composition of the invention are prepared from the following raw materials in parts by weight: 0.5-1 part of mint, 3-4 parts of dried ginger and 3-5 parts of cinnamon. The medicine composition can be prepared into an external preparation, and can also be placed in a waist support to be assisted with a heating device and a magnet to play the role of synergistic interaction of medicine therapy, heat therapy and magnetic therapy. The medicine composition and the waist support for treating the lumbar facet joint disorder syndrome have the characteristics of rapid pain relief and obvious curative effect, and provide a new choice for the public to treat the lumbar facet joint disorder syndrome.
Description
Technical field
The present invention relates to treat the pharmaceutical composition of derangement syndrome of small joints in lumbar spine and contain the waist holder that this preparation of pharmaceutical compositions forms, belong to field of medicaments.
Background technology
Derangement syndrome of small joints in lumbar spine is also referred to as little synovium of joint incarceration.Many because slight acute lumbar muscle sprain or bend over to stand up suddenly embeds between the little joint synovial membrane, causes little locked joint or dislocation, makes the vertebra limitation of activity.Thundering severe pain takes place after the wound immediately, and patient can't be stood.Patient often bends body and lies on one's side, and nervous, muscular tone dare not be moved, and fears that others touches or moves, and any activity, cough, the vibrations of spinal column all can make pain increase the weight of.Because pain, psoas muscle is the protectiveness muscular spasm, and lumbar vertebra flattens or be protruding after a while or slightly side is protruding.The swelling of synovial membrane upper end can stimulate the nerve root that is positioned at intervertebral foramina, produces radiated pain, increasing the weight of when straightening one's back excessively, and tension synovial membrane when bending over, stimulation alleviates, and pain is also light.But primary disease is mainly based on lumbago, and the nerve root irritation symptom occurs less.
Treat derangement syndrome of small joints in lumbar spine at present, Western medicine is based on anti-inflammation analgesic for oral administration, and Chinese medicine is based on promoting blood circulation and stopping pain.But Western medicine and Chinese medicine all have certain stimulation to gastrointestinal, and taking Western medicine for a long time also may influence hepatic and renal function, and patient's compliance is poor.
Existing waist holder has only passive waist holder, have also that to contain thermotherapy, magnetic therapy, medication be the therapeutic type waist holder of one, the heating system of wherein all heat treatment therapeutic device has the mode of near infrared light, far red light, resistance heating or chemistry heating, and the magnet of magnetic therapy generally adopts magnetic sheet.Existing waist holder is used for the treatment of diseases such as prolapse of lumbar intervertebral disc more.At present still do not have the waist holder that to treat derangement syndrome of small joints in lumbar spine, do not have Herba Menthae, Rhizoma Zingiberis, Cortex Cinnamomi compatibility treatment derangement syndrome of small joints in lumbar spine yet, not with Herba Menthae, Rhizoma Zingiberis, Cortex Cinnamomi compatibility relevant report yet in conjunction with the therapeutic type waist holder of thermotherapy or magnetic therapy.
Summary of the invention
Technical problem to be solved by this invention provides a kind of pharmaceutical composition for the treatment of derangement syndrome of small joints in lumbar spine.
Pharmaceutical composition of the present invention, its active component are to contain the following weight proportion raw material to be prepared from: 0.5～1 part of Herba Menthae, 3～4 parts of Rhizoma Zingiberiss, 3～5 parts of Cortex Cinnamomis.Can be on the basis of primary raw material Herba Menthae, Rhizoma Zingiberis, Cortex Cinnamomi, those skilled in the art can add the medicine that other has the drug for invigorating blood circulation and eliminating stasis effect or contains volatile ingredient again according to clinical indication and clinical needs, with the performance assosting effect.
Pharmaceutical composition of the present invention, its active component are to be prepared from by the following weight proportion raw material: 0.5～1 part of Herba Menthae, 3～4 parts of Rhizoma Zingiberiss, 3～5 parts of Cortex Cinnamomis.1 part of preferred feedstock Herba Menthae, 3 parts of Rhizoma Zingiberiss, 5 parts of compatibilities of Cortex Cinnamomi use.
Pharmaceutical composition of the present invention is to be active component with Herba Menthae, Rhizoma Zingiberis, Cortex Cinnamomi, adds the external preparation that acceptable accessories or complementary composition are prepared from.
Another technical problem to be solved by this invention provides the waist holder that is used for the treatment of derangement syndrome of small joints in lumbar spine.
Waist holder of the present invention comprises heater, contains medicine device, and the pharmaceutical composition of wherein containing in the medicine device is to contain the following weight proportion raw material to be prepared from: 0.5～1 part of Herba Menthae, 3～4 parts of Rhizoma Zingiberiss, 3～5 parts of Cortex Cinnamomis.
This waist holder also comprises magnet, is used to produce magnetic field.
This waist holder also can include only magnet, contain medicine device, does not comprise heater.
Pharmaceutical composition of the present invention has significant curative effect at the treatment derangement syndrome of small joints in lumbar spine, and especially the form with the waist holder is aided with heater and magnet generation magnetic field, and therapeutic effect is more obvious.Adopt pharmaceutical composition of the present invention and waist holder treatment derangement syndrome of small joints in lumbar spine to have rapid, the evident in efficacy characteristics of pain relieving, provide new selection for clinical.
Obviously, according to foregoing of the present invention,,, can also make modification, replacement or the change of other various ways not breaking away under the above-mentioned basic fundamental thought of the present invention prerequisite according to the ordinary skill knowledge and the customary means of this area.
Description of drawings
Fig. 1 waist holder of the present invention medial surface figure.
Fig. 2 waist holder of the present invention back view.
The specific embodiment
Pharmaceutical composition of the present invention, its active component are to contain the following weight proportion raw material to be prepared from: 0.5～1 part of Herba Menthae, 3～4 parts of Rhizoma Zingiberiss, 3～5 parts of Cortex Cinnamomis.In this scope, all can produce the effect of treatment derangement syndrome of small joints in lumbar spine.Can also be on the basis of primary raw material Herba Menthae, Rhizoma Zingiberis, Cortex Cinnamomi,, add other active component performance assosting effect again according to clinical needs.
Rhizoma Zingiberis has the effect of calmness, analgesia, antiinflammatory, blood vessel dilating and blood circulation promoting; Herba Menthae can optionally act on the Cold receptor of skin or mucosa, the reflection of the generation sense of cold, cause skin, mucosa vasoconstriction, blood vessel to deep tissue also causes reflexive variation simultaneously, adjust vascular function, therefore produce therapeutical effect, the Herba Menthae external can be anaesthetized teleneuron, and that topical application has is refrigerant, antipruritic, antiinflammatory, analgesic effect; Cortex Cinnamomi has the effect of calmness, analgesia, transdermal, reuses with pain relieving.Three kinds of material combinations use, and the pain that derangement of lumbar facet joint is caused has remarkable analgesia, antiphlogistic effect.
Further preferred, active ingredient in pharmaceutical of the present invention is to contain the following weight proportion raw material to be prepared from: 1 part of Herba Menthae, 3 parts of Rhizoma Zingiberiss, 5 parts of Cortex Cinnamomis.This proportioning is the best proportioning of this material combination.
Active ingredient in pharmaceutical of the present invention is to be prepared from by the following weight proportion raw material: 0.5～1 part of Herba Menthae, 3～4 parts of Rhizoma Zingiberiss, 3～5 parts of Cortex Cinnamomis.In this scope, all can produce the effect of treatment derangement syndrome of small joints in lumbar spine.
Further preferred, its active component is to be prepared from by following optimum weight proportion raw material: 1 part of Herba Menthae, 3 parts of Rhizoma Zingiberiss, 5 parts of Cortex Cinnamomis.
Pharmaceutical composition of the present invention, it is to be active component with Herba Menthae, Rhizoma Zingiberis, Cortex Cinnamomi, adds the external preparation that acceptable accessories or complementary composition are prepared from.
Particularly, external preparation can adopt tincture, paste, ointment, patch, hot compress agent and fomentation agent etc., decides according to clinical user demand.
Waist holder of the present invention comprises heater, contains medicine device, it is characterized in that the pharmaceutical composition of containing in the medicine device is to contain the following weight proportion raw material to be prepared from: 0.5～1 part of Herba Menthae, 3～4 parts of Rhizoma Zingiberiss, 3～5 parts of Cortex Cinnamomis.
Wherein said Sheng medicine device can be sack, also can be for ease of other container of splendid attire medicine.
Pharmaceutical composition preferred feedstock weight proportion is: 1 part of Herba Menthae, 3 parts of Rhizoma Zingiberiss, 5 parts of Cortex Cinnamomis.
Heater can be selected existing heater, as near infrared light, far red light, hot compress bag and resistance heating etc.
Adopting heat penetration skin technology is the preferred mode of heating of waist holder of the present invention.Heat penetration skin technology claims oxidation heating technology to be made up of high-purity reduced iron powder and catalyst such as medical activated carbon, sodium chloride again.Its weight proportion is 25 parts of high-purity reduced iron powders, 8 parts of medical activated carbons, 5 parts in sodium chloride.Heat penetration skin technology is generated heat by oxidation, and the long-acting quick heat production of energy, self-heating reach 30 hours action time.
Heater needs heating temp is controlled between 42～52 ℃, owing under long thermodynamic activity, blood circulation is dredged smooth effect obviously, can impel telangiectasis, acceleration blood flow, rapid transdermal.Active component in the pharmaceutical composition of the present invention can quicken to the site of disease infiltration by heating power, because the dual function of heat and medicine is arranged, can bring into play the effect of dredging smooth passages through which vital energy circulates, circulation QI and blood rapidly.Heat is then gone, and is cold then coagulate, and pharmaceutical composition of the present invention plays temperature three-way meridian by heating power, blood circulation promoting and blood stasis dispelling, and the effect of anti-inflammatory analgesic, curative effect is more remarkable.
Waist holder of the present invention can also be provided with magnet, can play the effect of magnetic therapy.The effect that magnetic therapy has more significantly analgesia, calmness, antiinflammatory, detumescence, improves blood circulation, dilutes algogenic substance.
The magnet that in the past was used for magnetic therapy mostly is magnetic sheet, and the preferred magnetic powder of the present invention produces magnetic field as magnet, can make the scope of the action of a magnetic field bigger, more even.Pain and inflammation that derangement of lumbar facet joint is caused have remarkable result; To magnetic powder fineness and the equal no requirement (NR) of content, only require that magnetic field intensity reaches 80～120Gs.
Waist holder of the present invention also can only comprise magnet, contain medicine device, does not contain heater.Can bring into play the effect of magnetic therapy and medication simultaneously.Heater of the present invention and magnet can place to be contained outside the medicine device, contains within the medicine device for the ease of preparation and long-pending also can the placing of minimizing waist base body.
The specific embodiment of form is described in further detail foregoing of the present invention again by the following examples.But this should be interpreted as that the scope of the above-mentioned theme of the present invention only limits to following example.All technology that realizes based on foregoing of the present invention all belong to scope of the present invention.
Below by clinical trial proof pharmaceutical composition of the present invention and contain the beneficial effect of the waist holder of this pharmaceutical composition.
It is the pharmaceutical composition A of 1 part of Herba Menthae, 1 part of Rhizoma Zingiberis, 1 part of Cortex Cinnamomi that the inventor once selected the raw material weight proportioning, and the pharmaceutical composition C of 1 part of Herba Menthae, 3 parts of Rhizoma Zingiberiss, the pharmaceutical composition B of 3 parts of Cortex Cinnamomis, 1 part of Herba Menthae, 3 parts of Rhizoma Zingiberiss, 5 parts of Cortex Cinnamomis carries out the clinical observation test.Adopt waist holder of the present invention, comprise heater, magnet, Sheng medicine device, difference powder charge compositions A, B, C in the medication device.The medical material consumption is 15g, pulverizes the fineness no requirement (NR).
Waist holder of the present invention such as Fig. 1 and Fig. 2 show.
The waist holder is mainly made by canvas, makes the belt 3 of both sides by wide type elastic cord, when wearing abdominal part adopt sticking with detain 2 and be connected, the belt 3 of degree of tightness belt and glue and is buckled the 2 different builds adjustment tightness of being convenient to according to the patient.Contain medicine device 1 and place waist holder of the present invention inboard, pasting the back skin when wearing; The partly also built-in four passive steel discs 4 of waist holder that are in lower back when wearing have guaranteed lumbosacral support strength.Contain medicine device 1 and include pharmaceutical composition A or B or C, oxidation exothermic mixture and magnetic powder, about 1 gram of magnetic powder consumption.
Usual method: be worn on lumbosacral region daytime, take off night and fill up under waist.The oxidation exothermic mixture heat production time is about 30 hours during wearing, and continues to wear waist holder of the present invention after heat production is intact, and pharmaceutical composition and magnet can continue to bring into play therapeutical effect.
Result of the test sees Table 1.
Raw material weight proportion clinical observation contrast test in table 1 pharmaceutical composition of the present invention
By test explanation, adopt the proportioning raw materials of 1 part of Herba Menthae, 3 parts of Rhizoma Zingiberiss, 5 parts of Cortex Cinnamomis, can be at the 3rd day the remarkable pain of reduction of patient just, fast than pharmaceutical composition A and pharmaceutical composition B onset time.
Clinical in observing pain patients 30 examples that medicine of a warm nature magnetic waist holder treatment derangement of lumbar facet joint causes, what test was used is waist holder of the present invention (showing as Fig. 1 and Fig. 2), comprise heater, magnet, Sheng medicine device, it is characterized in that the pharmaceutical composition of containing in the medicine device is to contain the following weight proportion raw material to be prepared from: 1 part of Herba Menthae, 3 parts of Rhizoma Zingiberiss, 5 parts of Cortex Cinnamomis.The medical material consumption is 15g, pulverizes the fineness no requirement (NR).
Adopt pain range estimation analogy point system (or to claim visual analogue scale, Visual analogous score or scale, abbreviation VAS) carries out efficacy evaluation, found that: the pain scores mean is 76.33 ± 15.20 before the treatment, treatment back one all pain scores means are 45.33 ± 17.90, treatment back two all pain scores means are 26.17 ± 16.54, have significant difference (P＜0.001) with comparing before the treatment.Be lumbago and the inflammation that magnetic waist of the present invention holder can be alleviated the derangement of lumbar facet joint patient effectively, pharmaceutical composition of the present invention is used for the treatment of derangement of lumbar facet joint in conjunction with electro-heat equipment and magnet and has levied significant curative effect.
Other proves pharmaceutical composition of the present invention by animal experiment study and contains the waist holder nonirritant and the side effect of this pharmaceutical composition.(side test, a side contrast) carried out repeatedly skin irritation test and sensitization test in SD rat spine both sides, the result, after the sensitization the 14th day, be subjected to the smooth skin allergies such as erythema, edema of not finding of 10 equal epidermises of examination group SD rat, show pharmaceutical composition of the present invention and waist holder nonirritant of the present invention.
Claims (4)
1. waist holder comprises magnet, heater, Sheng medicine device, it is characterized in that, the pharmaceutical composition of containing in the medicine device is to be prepared from by the following weight proportion raw material: 0.5～1 part of Herba Menthae, 3～4 parts of Rhizoma Zingiberiss, 3～5 parts of Cortex Cinnamomis.
2. waist holder according to claim 1 is characterized in that: the pharmaceutical composition of containing in the medicine device is to be prepared from by the following weight proportion raw material: 1 part of Herba Menthae, 3 parts of Rhizoma Zingiberiss, 5 parts of Cortex Cinnamomis.
3. waist holder according to claim 1 is characterized in that, the temperature range of described heater heating is 42 ℃～52 ℃.
4. waist holder according to claim 1 is characterized in that, described magnet is a magnetic powder, and magnetic field intensity is 80～120Gs.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007100486522A CN101057959B (en) | 2007-03-16 | 2007-03-16 | Pharmaceutical composition for treating lumbar facet joint disorder syndrome and waist support |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007100486522A CN101057959B (en) | 2007-03-16 | 2007-03-16 | Pharmaceutical composition for treating lumbar facet joint disorder syndrome and waist support |
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| Publication Number | Publication Date |
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| CN101057959A CN101057959A (en) | 2007-10-24 |
| CN101057959B true CN101057959B (en) | 2010-08-04 |
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| CN2007100486522A Active CN101057959B (en) | 2007-03-16 | 2007-03-16 | Pharmaceutical composition for treating lumbar facet joint disorder syndrome and waist support |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579982A (en) * | 2012-03-05 | 2012-07-18 | 杨彦君 | Externally-applied patch of for local point to treat gynecologic pelvic inflammatory disease and preparation method thereof |
| CN104001262B (en) * | 2014-06-09 | 2016-04-06 | 李长昊 | A kind of Pharmaceutical composition and the treatment belt containing this Pharmaceutical composition |
| CN104873323A (en) * | 2015-06-19 | 2015-09-02 | 广西达庆生物科技有限公司 | Medical magnetic therapy type hot compressing patch for treating soft tissue pain and preparation method thereof |
| CN107510830A (en) * | 2017-08-22 | 2017-12-26 | 莫兆钦 | It is a kind of to treat gout, dysmenorrhoea and carsick seasick Chinese prescription and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1071590A (en) * | 1991-10-19 | 1993-05-05 | 李军 | A kind of health promoting belt and manufacture method thereof |
| CN1095287A (en) * | 1993-05-19 | 1994-11-23 | 王国政 | Abdominal protecting medicine for external use |
| CN1100960A (en) * | 1993-10-01 | 1995-04-05 | 樊自清 | Combined health-care bag and its health belt and health clothing |
| CN1065776C (en) * | 1995-05-12 | 2001-05-16 | 中国科学院化学研究所 | Series health-care band of eucommia bark gel and its preparation and usage |
| CN1778405A (en) * | 2004-11-26 | 2006-05-31 | 鞠文军 | Externally-applied heat-temperature therapeutic health-care bag with Chinese medicine |
-
2007
- 2007-03-16 CN CN2007100486522A patent/CN101057959B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1071590A (en) * | 1991-10-19 | 1993-05-05 | 李军 | A kind of health promoting belt and manufacture method thereof |
| CN1095287A (en) * | 1993-05-19 | 1994-11-23 | 王国政 | Abdominal protecting medicine for external use |
| CN1100960A (en) * | 1993-10-01 | 1995-04-05 | 樊自清 | Combined health-care bag and its health belt and health clothing |
| CN1065776C (en) * | 1995-05-12 | 2001-05-16 | 中国科学院化学研究所 | Series health-care band of eucommia bark gel and its preparation and usage |
| CN1778405A (en) * | 2004-11-26 | 2006-05-31 | 鞠文军 | Externally-applied heat-temperature therapeutic health-care bag with Chinese medicine |
Non-Patent Citations (1)
| Title |
|---|
| 说明书第3页第5行. * |
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| CN101057959A (en) | 2007-10-24 |
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