CN101049421A - Preparation of Chinese traditional medicine for treating genital herpes - Google Patents
Preparation of Chinese traditional medicine for treating genital herpes Download PDFInfo
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- CN101049421A CN101049421A CN 200710099193 CN200710099193A CN101049421A CN 101049421 A CN101049421 A CN 101049421A CN 200710099193 CN200710099193 CN 200710099193 CN 200710099193 A CN200710099193 A CN 200710099193A CN 101049421 A CN101049421 A CN 101049421A
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Abstract
A Chinese medicine for treating genital herps is prepared from more than 10 Chinese- medicinal materials including anemarrhena rhizome, phelodendron bark, rehmannia root, isatis root, etc. Its advantages are sure curative effect, high safety, and no toxic by effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of genital herpes, is that a kind of genital herpes for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Genital herpes also is the pudendum herpes, is a kind of disease that is caused by virus.Mainly be to propagate by sexual intercourse, patient and carrier are the main sources of infection.Abroad, its sickness rate accounts for the 3rd of sexually transmitted disease (STD).In case catch this disease, very tired, small number of patients is difficult to cure all the life.Virus can enter human body through genital skin or the small breakage of mucosa.At first, enter blood then, send out by blood circulation and nervous pathway in the porch breeding.The crowd that betiding property of genital herpes is active, economic condition is poor, sanitary condition difference and sexual relationship confusion person, the easiest infection that is subjected to genital herpes.
Genital herpes is called the pudendum herpes again, is the phallic inflammatory skin disease that is caused by II type herpesvirus infection.Be characterized in the primary lesion of limitation and warming up at same position recurrence work.The pathogen of genital herpes is a herpes simplex virus, is called for short: HSV.Herpes simplex virus only needed to be killed in 30 minutes when damp and hot 52 ℃ or xeothermic 90 ℃, but can survive a few days at low temperatures.Herpes simplex virus can be divided into amphitypy according to the difference of its antigenic property.Be HSV-I and HSV-II type, I type herpesvirus mainly is present in human airway, lip, conjunctiva, cornea and skin, causes the class disease performance at these positions, is commonly referred to as herpes simplex, does not belong to sexually transmitted disease.II type herpesvirus mainly is present in women's cervix uteri mouth, vagina, pudendum mouth and urethra; The male then is present in penis and urethral orifice, is basically to invade waist following skin and mucosa place.The infection of genital herpes is based on immediate contagion.Because herpesvirus external can not long term survival.Virus through mucous membrane or skin injury place enter human body, and earlier at the porch growth and breeding, the capable or nervous pathway of back menses is sent out.The contact of many trafficability characteristics and infect, the sickness rate after the property contact is 30%～50%, the infectiousness of primary disease is extremely strong, allly with the male who suffers from herpes of penis the disposable women who contacts takes place, and has 60%～80% can send out primary disease.
Infective virus and falling ill is called primary genitalia herpes first.Generally need 3～5 days from touching morbidity.Infection place has burn feeling earlier, and the very fast red little pimple that takes place on the erythema basis in groups is with pruritus.Become vesicle or papulovesicle very soon, the critically ill patient skin lesion became pustule after 3～5 days, then formed erosion in blocks and ulcer, and pain is arranged, about 20 days of incrustation recovery from illness at last, the whole course of disease.The primary genitalia herpes General Symptoms obviously, heating, headache, discomfort, leucorrhoea grow in quantity, dysuria, regional glandular enlargement etc. can be arranged.In primary genitalia herpes, there is 60% patient in 1 year, to recur approximately.The inducement of recurrence may be heating, menstrual onset, sexual intercourse, excited, dyspepsia and climate change etc.Prodrome is arranged earlier during outbreak, lighter as local tingling and parasthenia, pain and pruritus.General Symptoms is not obvious.Infringement place begins to be vesicle or pustule, later ulcer, and incrustation, recovery from illness generally can not stay cicatrix about 10 days.
In Chinese medicine, genital herpes belongs to the category of " erosion of vulva ", " cloudy infantile malnutrition ", " scabies infantile malnutrition ".Primary genitalia herpes and recurrent genital herpes stage of attack, show as part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels syndrome of dampness-heat of liver channel more clinically, and recurrent genital herpes non-stage of attack shows as in the noxious dampness more is stranded syndrome of lingering pathogen due to deficient vital qi.The herpes stage of attack, should get rid of evils based on the heat-clearing and toxic substances removing dampness removing in the treatment, and non-stage of attack should be with supplementing QI and nourishing YIN, and it is main that invigorating spleen to remove dampness is set upright.Therefore the traditional Chinese medical science has better curative effect to the recurrence of treatment genital herpes.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of genital herpes.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.5～6 parts of 1.5～6 parts of Radix Rehmanniae Preparata of 1.5～6 portions of Cortex Phellodendris of the Rhizoma Anemarrhenae
1.0～4 parts of 1.0～4 parts of Radix Isatidis of 1.0～4 parts of Radix Bupleuri of Rhizoma Dioscoreae
1.0～4 parts of 1.0～4 parts of Herba Leonuris of 1.0～4 parts of Radixs Astragali of the Rhizoma Atractylodis Macrocephalae
0.1～2 part of 0.1～2 part of Fructus Corni of 0.1～2 portion of Radix Glycyrrhizae of Herba Artemisiae Scopariae
The weight proportion of each raw material of optimization formula of the present invention is:
2.5～3.5 parts of 2.5～3.5 parts of Radix Rehmanniae Preparata of 2.5～3.5 portions of Cortex Phellodendris of the Rhizoma Anemarrhenae
1.5～2.5 parts of 1.5～2.5 parts of Radix Isatidis of 1.5～2.5 parts of Radix Bupleuri of Rhizoma Dioscoreae
1.5～2.5 parts of 1.5～2.5 parts of Herba Leonuris of 1.5～2.5 parts of Radixs Astragali of the Rhizoma Atractylodis Macrocephalae
0.5～1.5 part of 0.5～1.5 part of Fructus Corni of 0.5～1.5 portion of Radix Glycyrrhizae of Herba Artemisiae Scopariae
The weight proportion of each raw material of optimum formula of the present invention is:
3 parts of 3 parts of Radix Rehmanniae Preparata of 3 portions of Cortex Phellodendris of the Rhizoma Anemarrhenae
2 parts of 2 parts of Radix Isatidis of 2 parts of Radix Bupleuri of Rhizoma Dioscoreae
2 parts of 2 parts of Herba Leonuris of 2 parts of Radixs Astragali of the Rhizoma Atractylodis Macrocephalae
1 part of 1 part of Fructus Corni of 1 portion of Radix Glycyrrhizae of Herba Artemisiae Scopariae
Drug action mechanism among the present invention is as follows:
Rhizoma Anemarrhenae nature and flavor hardship, sweet, cold.Return lung, stomach, kidney channel.Has clearing away heat-fire, the effect of promoting the production of body fluid and moisturizing.Can treat that fever caused by exogenous pathogenic factors, hyperpyrexia excessive thirst, tuberculosis heating, cough due to lung-heat, osteopyrexia and fever, interior-heat are quenched one's thirst, the dryness of the intestine constipation, dysuria, diabetes etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 817th page).
Cortex Phellodendri nature and flavor hardship, cold.Return kidney, urinary bladder channel.Have heat clearing and damp drying, pathogenic fire purging removes steams, and the effect of skin ulcer is treated in detoxifcation.Can treat damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.The stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.Can treat hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency etc.(the 251st page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The Radix Rehmanniae Preparata nature and flavor are sweet, tepor.Return liver, kidney channel.Have nourishing YIN and supplementing blood, beneficial essence is filled out the effect of marrow.Can treat the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair etc.(the 95th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The Rhizoma Dioscoreae property of medicine is sweet, flat.Return spleen, lung, kidney channel.Have spleen reinforcing, support lung, reinforce the kidney, the effect that benefit is smart.Can treat diarrhea due to hypofunction of the spleen, the lack of appetite edema, cough and asthma due to lung deficiency is quenched one's thirst, seminal emission, leukorrhagia, the frequent micturition of suffering from a deficiency of the kidney.Carbuncle is controlled in external, scrofula etc.(the 218th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Bupleuri nature and flavor hardship, be slightly cold.Return liver, gallbladder meridian.Effect with reconciling superficies and interior, soothing the liver, yang invigorating.Can treat alternate attack of chill and fever, fullness in the chest and hypochondriac pain, deafness, headache and dizziness, malaria, dysentery proctoptosis, menoxenia, uterine prolapse, flu, upper respiratory tract infection, hepatitis, cholecystitis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1004th page).
Radix Isatidis property of medicine hardship, cold.GUIXIN, lung, liver, stomach warp.Has heat clearing away, detoxifcation, removing heat from blood, the effect of sore-throat relieving.Can treat anemopyretic cold, influenza, epidemic encephalitis, encephalitis b, major part pestilence, scarlet fever, erysipelas, mumps, laryngopharynx swelling and pain, jaundice, chickenpox, measles etc.(the 1806th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Atractylodis Macrocephalae nature and flavor hardship, sweet, warm.Return spleen, stomach warp.Have invigorating the spleen and replenishing QI, the dampness diuresis and in antiabortive, strengthening superficial resistance to stop perspiration, anticancer effect.Can treat that pulmonary carcinoma, gastric cancer, cervical cancer, insufficiency of the spleen lack of appetite, abdominal distention are had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement, asthma, phlegmatic cough, leucorrhea, nebulousurine, seminal emission, gonorrhea, frequent micturition etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 447th page).
Radix Astragali nature and flavor are sweet, warm.Return lung, spleen channel.Have benefit and defend consolidating superficial resistance, inducing diuresis to remove edema, poison holding, the effect of granulation promoting.That can treat that internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, metrorrhagia and leukorrhagia, spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, carbuncle do not burst or burst does not hold back and the disease of all weakness of QI blood deficiency etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1074th page).
Herba Leonuri nature and flavor hardship, suffering, be slightly cold.Return liver, pericardium channel.Effect with regulating menstruation and activating blood, promoting tissue regeneration by removing blood stasis, inducing diuresis to remove edema.Can treat menoxenia, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria, have blood in stool, carbuncle skin infection etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1050th page).
The little hardship of the Herba Artemisiae Scopariae property of medicine, little suffering are slightly cold.Return spleen, stomach, urinary bladder channel.Has clearing away heat-damp and promoting diuresis, the effect of jaundice eliminating.Can treat jaundice, dysuria, eczema pruritus etc.(the 2146th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Glycyrrhizae property of medicine is sweet, and is flat.Return spleen, stomach, the heart, lung meridian.Have and middle emergency lung moistening, detoxifcation, the effect of coordinating the actions of various ingredients in a prescription.Can treat weakness of the spleen and stomach, asthenia lack of appetite, stomachache loose stool, the anxious pain of extremity contraction, cardiopalmus, hysteria, consumptive lung disease cough; Give birth to controlling laryngopharynx swelling and pain, the carbuncle pyogenic infections from tumour or sore, infantile carbuncle reaches medicine, alimentary toxicosis etc.(the 792nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Corni nature and flavor acid, puckery, tepor.Return liver, kidney channel.Has liver and kidney tonifying, the effect of essence astringing and desertion stemming.Can treat vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating collapse.Interior-heat is quenched one's thirst etc.(the 22nd page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with the Rhizoma Anemarrhenae, Cortex Phellodendri and Radix Rehmanniae Preparata; With Rhizoma Dioscoreae, Radix Bupleuri, Radix Isatidis, the Rhizoma Atractylodis Macrocephalae, the Radix Astragali and Herba Leonuri is ministerial drug; With Herba Artemisiae Scopariae, Radix Glycyrrhizae and Fructus Corni is adjuvant.All medicines are harmonious, and are total to the tool Replenishing QI and nourishing YIN, the effect of strengthening vital QI to eliminate pathogenic factors.The treatment genital herpes has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment genital herpes of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat genital herpes, and the prevention of genital herpes is also had good effect, and the treatment genital herpes has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment genital herpes; Treatment genital herpes patient 15 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.Cure 11 examples and account for 73.33%, 3 examples that take a turn for the better account for 20%, and more 1 example does not account for 6.67%, and total effective rate reaches 93.33%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
3 parts of 3 parts of Radix Rehmanniae Preparata of 3 portions of Cortex Phellodendris of the Rhizoma Anemarrhenae
2 parts of 2 parts of Radix Isatidis of 2 parts of Radix Bupleuri of Rhizoma Dioscoreae
2 parts of 2 parts of Herba Leonuris of 2 parts of Radixs Astragali of the Rhizoma Atractylodis Macrocephalae
1 part of 1 part of Fructus Corni of 1 portion of Radix Glycyrrhizae of Herba Artemisiae Scopariae
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment genital herpes that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.One month is a course of treatment.
Claims (3)
1, a kind of Chinese medicine preparation for the treatment of genital herpes is characterized in that it is made by the following weight proportion raw material:
1.5～6 parts of 1.5～6 parts of Radix Rehmanniae Preparata of 1.5～6 portions of Cortex Phellodendris of the Rhizoma Anemarrhenae
1.0～4 parts of 1.0～4 parts of Radix Isatidis of 1.0～4 parts of Radix Bupleuri of Rhizoma Dioscoreae
1.0～4 parts of 1.0～4 parts of Herba Leonuris of 1.0～4 parts of Radixs Astragali of the Rhizoma Atractylodis Macrocephalae
0.1～2 part of 0.1～2 part of Fructus Corni of 0.1～2 portion of Radix Glycyrrhizae of Herba Artemisiae Scopariae
2, a kind of Chinese medicine preparation for the treatment of genital herpes according to claim 1, wherein the weight proportion of each raw material is:
2.5～3.5 parts of 2.5～3.5 parts of Radix Rehmanniae Preparata of 2.5～3.5 portions of Cortex Phellodendris of the Rhizoma Anemarrhenae
1.5～2.5 parts of 1.5～2.5 parts of Radix Isatidis of 1.5～2.5 parts of Radix Bupleuri of Rhizoma Dioscoreae
1.5～2.5 parts of 1.5～2.5 parts of Herba Leonuris of 1.5～2.5 parts of Radixs Astragali of the Rhizoma Atractylodis Macrocephalae
0.5～1.5 part of 0.5～1.5 part of Fructus Corni of 0.5～1.5 portion of Radix Glycyrrhizae of Herba Artemisiae Scopariae.
3, a kind of Chinese medicine preparation for the treatment of genital herpes according to claim 1, wherein the weight proportion of each raw material is:
3 parts of 3 parts of Radix Rehmanniae Preparata of 3 portions of Cortex Phellodendris of the Rhizoma Anemarrhenae
2 parts of 2 parts of Radix Isatidis of 2 parts of Radix Bupleuri of Rhizoma Dioscoreae
2 parts of 2 parts of Herba Leonuris of 2 parts of Radixs Astragali of the Rhizoma Atractylodis Macrocephalae
1 part of 1 part of Fructus Corni of 1 portion of Radix Glycyrrhizae of Herba Artemisiae Scopariae.
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| CN 200710099193 CN101049421A (en) | 2007-05-16 | 2007-05-16 | Preparation of Chinese traditional medicine for treating genital herpes |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015010205A1 (en) * | 2013-07-22 | 2015-01-29 | Université Du Québec À Chicoutimi | Use of plant extracts against herpes simplex virus |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015010205A1 (en) * | 2013-07-22 | 2015-01-29 | Université Du Québec À Chicoutimi | Use of plant extracts against herpes simplex virus |
| US10716821B2 (en) | 2013-07-22 | 2020-07-21 | Université Du Québec A Chicoutimi | Use of plant extracts against herpes simplex virus |
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