CN101048162B - 涉及新颖化合物及其靶标的组合物和方法 - Google Patents
涉及新颖化合物及其靶标的组合物和方法 Download PDFInfo
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- CN101048162B CN101048162B CN2005800363803A CN200580036380A CN101048162B CN 101048162 B CN101048162 B CN 101048162B CN 2005800363803 A CN2005800363803 A CN 2005800363803A CN 200580036380 A CN200580036380 A CN 200580036380A CN 101048162 B CN101048162 B CN 101048162B
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- 0 C*c1ccccc1 Chemical compound C*c1ccccc1 0.000 description 24
- YXFVVABEGXRONW-UHFFFAOYSA-N Cc1ccccc1 Chemical compound Cc1ccccc1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 11
- ALLIZEAXNXSFGD-UHFFFAOYSA-N Cc(cccc1)c1-c1ccccc1 Chemical compound Cc(cccc1)c1-c1ccccc1 ALLIZEAXNXSFGD-UHFFFAOYSA-N 0.000 description 3
- XDTMQSROBMDMFD-UHFFFAOYSA-N C1CCCCC1 Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 description 2
- XVCMGQVQWZFHDZ-UHFFFAOYSA-N CCc(cc1)ccc1OC(F)(F)F Chemical compound CCc(cc1)ccc1OC(F)(F)F XVCMGQVQWZFHDZ-UHFFFAOYSA-N 0.000 description 2
- ZZLCFHIKESPLTH-UHFFFAOYSA-N Cc(cc1)ccc1-c1ccccc1 Chemical compound Cc(cc1)ccc1-c1ccccc1 ZZLCFHIKESPLTH-UHFFFAOYSA-N 0.000 description 2
- LPKITZIDHBWGFH-UHFFFAOYSA-N CC1=CC=C[I]=C1 Chemical compound CC1=CC=C[I]=C1 LPKITZIDHBWGFH-UHFFFAOYSA-N 0.000 description 1
- DPJHZJGAGIWXTD-UHFFFAOYSA-N CS(c(cc1)ccc1F)(=O)=O Chemical compound CS(c(cc1)ccc1F)(=O)=O DPJHZJGAGIWXTD-UHFFFAOYSA-N 0.000 description 1
- LXINKRZIJMGCDO-UHFFFAOYSA-N CSc(cc1)ccc1-c1ccccc1 Chemical compound CSc(cc1)ccc1-c1ccccc1 LXINKRZIJMGCDO-UHFFFAOYSA-N 0.000 description 1
- HXQDSHSATAEREW-UHFFFAOYSA-N Cc(cc1)cc(C2)c1NC2=O Chemical compound Cc(cc1)cc(C2)c1NC2=O HXQDSHSATAEREW-UHFFFAOYSA-N 0.000 description 1
- UDHAWRUAECEBHC-UHFFFAOYSA-N Cc(cc1)ccc1I Chemical compound Cc(cc1)ccc1I UDHAWRUAECEBHC-UHFFFAOYSA-N 0.000 description 1
- RWXZXCZBMQPOBF-UHFFFAOYSA-N Cc1ccc2nc[nH]c2c1 Chemical compound Cc1ccc2nc[nH]c2c1 RWXZXCZBMQPOBF-UHFFFAOYSA-N 0.000 description 1
- MSQNDCZKLKZUBL-UHFFFAOYSA-N IC1=CC2=CCN=C2C=C1 Chemical compound IC1=CC2=CCN=C2C=C1 MSQNDCZKLKZUBL-UHFFFAOYSA-N 0.000 description 1
- UCHJMJAOCFQQDU-UHFFFAOYSA-N Oc(cc1)ccc1C(c1c2ccc(Cl)c1)=NCCN2S Chemical compound Oc(cc1)ccc1C(c1c2ccc(Cl)c1)=NCCN2S UCHJMJAOCFQQDU-UHFFFAOYSA-N 0.000 description 1
- UHOVQNZJYSORNB-UHFFFAOYSA-N c1ccccc1 Chemical compound c1ccccc1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 1
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- Health & Medical Sciences (AREA)
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- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
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- Diabetes (AREA)
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- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
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- Communicable Diseases (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/935,333 US20050113460A1 (en) | 1999-04-30 | 2004-09-07 | Compositions and methods relating to novel compounds and targets thereof |
US10/935,333 | 2004-09-07 | ||
PCT/US2005/031942 WO2006029245A2 (en) | 2004-09-07 | 2005-09-07 | Compositions and methods relating to novel compounds and targets thereof |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2011103284209A Division CN102512424A (zh) | 2004-09-07 | 2005-09-07 | 涉及新颖化合物及其靶标的组合物和方法 |
Publications (2)
Publication Number | Publication Date |
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CN101048162A CN101048162A (zh) | 2007-10-03 |
CN101048162B true CN101048162B (zh) | 2011-12-28 |
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ID=36036988
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
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CN2011103284209A Pending CN102512424A (zh) | 2004-09-07 | 2005-09-07 | 涉及新颖化合物及其靶标的组合物和方法 |
CN2005800363803A Expired - Fee Related CN101048162B (zh) | 2004-09-07 | 2005-09-07 | 涉及新颖化合物及其靶标的组合物和方法 |
Family Applications Before (1)
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CN2011103284209A Pending CN102512424A (zh) | 2004-09-07 | 2005-09-07 | 涉及新颖化合物及其靶标的组合物和方法 |
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Cited By (3)
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US8759340B2 (en) | 2007-11-06 | 2014-06-24 | The Regents Of The University Of Michigan | Benzodiazepinone compounds useful in the treatment of skin conditions |
US8791104B2 (en) | 2005-11-01 | 2014-07-29 | The Regents Of The University Of Michigan | 1,4-benzodiazepine-2,5-diones with therapeutic properties |
US8809323B2 (en) | 1999-04-30 | 2014-08-19 | The Regents Of The University Of Michigan | Therapeutic applications of pro-apoptotic benzodiazepines |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
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US20060025388A1 (en) | 1999-04-30 | 2006-02-02 | Glick Gary D | Compositions and methods relating to novel compounds and targets thereof |
US20050113460A1 (en) * | 1999-04-30 | 2005-05-26 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
US7572788B2 (en) * | 1999-04-30 | 2009-08-11 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
US20040176358A1 (en) * | 1999-04-30 | 2004-09-09 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
US7276348B2 (en) * | 1999-04-30 | 2007-10-02 | Regents Of The University Of Michigan | Compositions and methods relating to F1F0-ATPase inhibitors and targets thereof |
WO2005061519A1 (en) * | 2003-12-19 | 2005-07-07 | Takeda San Diego, Inc. | Kinase inhibitors |
US8019413B2 (en) | 2007-03-19 | 2011-09-13 | The Invention Science Fund I, Llc | Lumen-traveling biological interface device and method of use |
US8353896B2 (en) | 2004-04-19 | 2013-01-15 | The Invention Science Fund I, Llc | Controllable release nasal system |
US7850676B2 (en) | 2004-04-19 | 2010-12-14 | The Invention Science Fund I, Llc | System with a reservoir for perfusion management |
US8512219B2 (en) | 2004-04-19 | 2013-08-20 | The Invention Science Fund I, Llc | Bioelectromagnetic interface system |
US8337482B2 (en) * | 2004-04-19 | 2012-12-25 | The Invention Science Fund I, Llc | System for perfusion management |
US8361013B2 (en) | 2004-04-19 | 2013-01-29 | The Invention Science Fund I, Llc | Telescoping perfusion management system |
US8092549B2 (en) | 2004-09-24 | 2012-01-10 | The Invention Science Fund I, Llc | Ciliated stent-like-system |
US7998060B2 (en) | 2004-04-19 | 2011-08-16 | The Invention Science Fund I, Llc | Lumen-traveling delivery device |
US7857767B2 (en) * | 2004-04-19 | 2010-12-28 | Invention Science Fund I, Llc | Lumen-traveling device |
US9011329B2 (en) | 2004-04-19 | 2015-04-21 | Searete Llc | Lumenally-active device |
JP2007533753A (ja) * | 2004-04-23 | 2007-11-22 | タケダ サン ディエゴ インコーポレイテッド | インドール誘導体及びキナーゼ阻害剤としてのその使用 |
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US8809323B2 (en) | 1999-04-30 | 2014-08-19 | The Regents Of The University Of Michigan | Therapeutic applications of pro-apoptotic benzodiazepines |
US8791104B2 (en) | 2005-11-01 | 2014-07-29 | The Regents Of The University Of Michigan | 1,4-benzodiazepine-2,5-diones with therapeutic properties |
US8759340B2 (en) | 2007-11-06 | 2014-06-24 | The Regents Of The University Of Michigan | Benzodiazepinone compounds useful in the treatment of skin conditions |
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WO2006029245A2 (en) | 2006-03-16 |
AU2005282461C1 (en) | 2010-06-03 |
CN102512424A (zh) | 2012-06-27 |
AU2005282461B2 (en) | 2009-11-05 |
US20050113460A1 (en) | 2005-05-26 |
EP2422788A2 (en) | 2012-02-29 |
US20080293700A1 (en) | 2008-11-27 |
IL218524A0 (en) | 2012-04-30 |
CN101048162A (zh) | 2007-10-03 |
EP2422788A3 (en) | 2012-07-11 |
JP2012197305A (ja) | 2012-10-18 |
IL181754A0 (en) | 2007-07-04 |
EP1786429A2 (en) | 2007-05-23 |
CA2579567A1 (en) | 2006-03-16 |
EP1786429A4 (en) | 2009-04-29 |
JP2008512477A (ja) | 2008-04-24 |
AU2005282461A1 (en) | 2006-03-16 |
WO2006029245A3 (en) | 2006-12-07 |
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