CN101041029A - Chinese traditional medicine for curing hepatitis B - Google Patents
Chinese traditional medicine for curing hepatitis B Download PDFInfo
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- CN101041029A CN101041029A CN 200710077739 CN200710077739A CN101041029A CN 101041029 A CN101041029 A CN 101041029A CN 200710077739 CN200710077739 CN 200710077739 CN 200710077739 A CN200710077739 A CN 200710077739A CN 101041029 A CN101041029 A CN 101041029A
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Abstract
The invention discloses a Chinese medicament for treating hepatitis B, wherein the raw materials include hooked uncaria, Chinese knotweed, siberian cocklebur fruit, giant knotweed rhizome, corktree bark, Loranthus mulberry mistletoe and yellow maize.
Description
Technical field: the present invention relates to a kind of Chinese medicine that can treat hepatitis B, specifically is the Chinese patent medicine of feedstock production with the Chinese herbal medicine.
Background technology: at present, there are 1.2 hundred million hepatitis B virus carrierss in China, and wherein hepatitis B patient has 3,000 ten thousand approximately, and from area distribution, south is higher than the north, and the east is higher than western part.In the hepatitis B virus carriers, have only the active hepatitis B patient of few part virus replication to have infectiousness.The infectious approach of hepatitis B virus has five: one, and blood-borne contains the blood of hepatitis B virus as input; The 2nd, close contact in life; The 3rd, spread through sex intercourse; The 4th, mother and baby's vertical transmission; The 5th, propagate in the doctor source, as use unclean syringe.
The prevention of hepatitis B is except blocking the above-mentioned route of infection, and best bet is the injection Hepatitis B virus vaccine, has injected Hepatitis B virus vaccine, has produced hbv antibody, just has been difficult for by hepatitis B virus infection.
The hepatitis B virus inspection comprises: 1. surface antigen; 2. surface antibody; 3.e antigen; 4.e antibody; 5. core antibody.If wherein the 1,3, the 5th, positive, be exactly " great three positive "; 1,4,5 positives claim " small three positive ".
Great three positive is meant that generally virus replication is active, and infectiousness is strong, and small three positive represents that virus replication is inactive, and its infectiousness is very little.
Concerning hepatitis B virus, the mankind also do not have a kind of very specific antiviral agents so far.Antiviral agents such as interferon preferably at present, nucleoside analog such as heptodin etc. also can only make HBeAg and HBV-DNA negative conversion rate reach 30%-40% or higher, but to the radical cure of turning out cloudy of hepatitis B, the mankind still do not have good recipe at present, and killing hepatitis B virus is a difficult problem of not capturing as yet in world today's scope.
Vast traditional Chinese medical science worker for unremitting effort has been done in the treatment of hepatitis B, though do not have to find the specific drug that hepatitis B is thoroughly turned out cloudy, does a lot to the treatment of hepatitis B patient and the control of the state of an illness, and the patent documentation of the parties concerned is also a lot, as:
1. " a kind of Chinese medicine watered pill preparation for the treatment of hepatitis B " application number 200410000922.9.2. " a kind of Chinese medicine for the treatment of hepatitis B ", application Shen number 02115832.0.
Purpose of the present invention is according to theory of Chinese medical science, treats the Chinese medicine of acute, chronic hepatitis in conjunction with the invention of modern medicine viewpoint, and attempts to reach the purpose of radical cure.
Summary of the invention: the traditional Chinese medical science thinks that hepatitis is because the turbid damp internal resistance is evil in the moonization, the evil criminal of damp and hot poison liver, and depression of liver-QI, the wind-phlegm blood stasis is detained and suffers from, and method of treatment is a heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, damp eliminating is reduced phlegm, replenishing QI to invigorate the spleen, nourishing the liver and kidney.Doctor trained in Western medicine thinks that hepatitis B is to immerse human body by hepatitis B virus, causes liver tissue injury, and method of treatment is to kill hepatitis B virus.The inventor, thinks for reaching the purpose of treatment or radical cure hepatitis B in conjunction with the modern medicine viewpoint according to motherland's theory of Chinese medical science, mainly should comprise three compositions in the prescription, the one, but the composition of the hepatitis B virus protein coat HBsAg that can go out; The 2nd, can suppress hepatitis B virus core polymerase HBV-DNAP active component; The 3rd, can kill the composition of Dane virus.The present invention concentrated on studies through the inventor on the basis of secret prescription handed down in the family from generation to generation according to above-mentioned viewpoint, inherited ancestors' meritorious achievements in 1997, with clinical drug treatment hepatitis B of the present invention, treated 30-40 people every year approximately, hundreds of people of settled the present, and therapeutic effect is obvious.It is open now will to fill a prescription, and benefiting the patient and to apply for national patent protection, and is willing to and the joint efforts of going together, and captures a difficult problem of killing hepatitis B virus.Therefore the present invention compares with the patent application of other treatment hepatitis B Chinese medicine, more has one's own knack.
The inventor thinks, but Rhizoma Polygoni Cuspidati, Cortex Phellodendri, Herba Taxilli can have the effect of the hepatitis B virus protein coat that goes out in the prescription, Herb Polygoni Chinensis, and Fructus Xanthii has the effect that suppresses the hepatitis B virus core polymerase activity, and Ramulus Uncariae Cum Uncis has the composition of killing hepatitis B virus.The present invention is raw materials used: Ramulus Uncariae Cum Uncis, Herb Polygoni Chinensis, Fructus Xanthii, Rhizoma Polygoni Cuspidati, Cortex Phellodendri, Herba Taxilli, Semen Maydis, be used, meet that the damp eliminating of traditional Chinese medical herbal treatment hepatitis B is reduced phlegm, blood circulation promoting and blood stasis dispelling, replenishing QI to invigorate the spleen, the principle of nourishing the liver and kidney, meet the modern medicine viewpoint again and think that hepatitis B is to invade human body by hepatitis B virus, continue to duplicate and cause the body's immunity disorder, cause the hepatic tissue chronic injury, become the viewpoint of the communicate illness that refractory heals.Introduce according to the Chinese medicine pharmacopeia: Ramulus Uncariae Cum Uncis; The heat clearing away suppressing the hyperactive liver, arresting convulsion relieves dizziness, high fever, infantile convulsions, epilepsy, etc.; Herb Polygoni Chinensis; Clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, the subcutaneous ulcer of harnessing the Yellow River; Fructus Xanthii: loose wind, pain relieving, damp eliminating; Rhizoma Polygoni Cuspidati; Removing blood stasis with potent drugs, stimulate the menstrual flow, dispel the wind, dampness removing, antibiotic, antiviral; Cortex Phellodendri: the subcutaneous ulcer of harnessing the Yellow River, heat clearing away, detoxifcation; Herba Taxilli: beneficial blood, invigorating the liver and kidney; Semen Maydis: contain the multiple nutrients vitamin, whet the appetite in the accent, lung benefiting mind calming, the diuresis of being good for the stomach.All medicine materials remove Fructus Xanthii according to recording little poison, but consumption seldom outside, all the other medicines are all without any side effects, can take the long period, to suppressing hepatitis B virus, hepatoprotective is of great benefit to, this is than the good part of general Western medicine.
Medicine of the present invention is pressed the row raw materials in weight portion and is made:
Ramulus Uncariae Cum Uncis 40-63 Herb Polygoni Chinensis 5-8 Fructus Xanthii 5-8 tiger branch 5-10 Cortex Phellodendri 5-8 Herba Taxilli 5-13 Semen Maydis 11-14;
Each raw material components optimum weight part proportioning of medicine of the present invention is:
Ramulus Uncariae Cum Uncis 51 Herb Polygoni Chinensiss 6.5 Fructus Xanthii 6.5 tiger branches 7 Cortex Phellodendris 6.5 Herba Taxillis 10 Semen Maydiss 12.5;
Raw material components weight of the present invention is pressed dry weight and is calculated.
Production method of the present invention is that dried raw material is weighed by prescription, and mixed powder is broken to the 60-80 order.
Based on powder, can be processed into the above dosage form of tablet, pill, capsule and other pharmaceutics.
Based on powder, in powder, add suitable amount of adhesive such as gelatin etc., the compression moulding drying is made pill, powder is incapsulated make the capsule medicament.
No matter powder, tablet, pill, capsule are obeyed three every day, each dose 1.4-1.6g, taking medicine before meal usefulness is swallowed with eliminating cold for resuscitation water.The child is cut down according to the circumstance.Points for attention are taken phase diet pluck and acidic food.
The specific embodiment: embodiment 1, get a dry Ramulus Uncariae Cum Uncis 40g Herb Polygoni Chinensis 5g Fructus Xanthii 5g tiger branch 5g Cortex Phellodendri 5g Herba Taxilli 5g Semen Maydis 11g and mix and pulverize 60-80 order fine powder, be distributed into 1.5g one parcel, obey every day 3 times, each clothes one bag, taking medicine before meal is used, use warm boiled water, period in a medicine diet pluck and acidic food.
Embodiment 2, Ramulus Uncariae Cum Uncis 63g Herb Polygoni Chinensis 8g Fructus Xanthii 8g tiger branch 10g Cortex Phellodendri 8g Herba Taxilli 13g Semen Maydis 14g mixed powder is broken to 60-80 order fine powder, be distributed into 1.5g one parcel, obey each clothes one bag every day 3 times, taking medicine before meal is used, use warm boiled water, period in a medicine diet pluck and acidic food.
Embodiment 3, take by weighing an exsiccant Ramulus Uncariae Cum Uncis 51g Herb Polygoni Chinensis 6.5g Fructus Xanthii 6.5g tiger branch 7g Cortex Phellodendri 6.5g Herba Taxilli 10g Semen Maydis 12.5g mixed powder and be broken to 60-80 order fine powder, be distributed into 1.5g one parcel, obey each clothes one bag every day 3 times, taking medicine before meal is used, with cold boiled water clothes, period in a medicine diet pluck and acidic food.
Based on the powder of embodiment 1-3, in powder, add an amount of binding agent such as gelatin etc., compression moulding, drying, make tablet; Powder is mixed with Mel, and pill is made in sealing wax protection in outside; During powder incapsulated, make the hard capsule medicament.
Which kind of dosage form no matter, each dosage 1.5g.
The present invention has following characteristics:
1. prescription of the present invention meets the Chinese medicine principle, having is turbid, damp eliminating, spleen invigorating, soothing the liver regulating QI, educate the function of nourishing liver, meet the modern medicine viewpoint again, think that hepatitis B is to immerse human body by hepatitis B virus, causes liver tissue injury, so medicine also has the antiviral function of antiphlogistic and bactericidal, according to inventor's viewpoint, drug effect can be gone directly and be killed hepatitis B virus in the nucleus.
2. the used Chinese medicine of the present invention is without any side effects, and the patient is not had any anaphylaxis, can take the long period, is of great benefit to suppressing hepatitis B virus and hepatoprotective.
3. dosage of the present invention is few, good effect, and 1.5g takes medicine at every turn.
4. production cost is low, need not famous and precious medicine.
5. have local characteristic, used medicine all is the common medicine in Guizhou.
6. be particularly suitable for treating chronic hepatitis.
Medical effect of the present invention:
Patient Lee *, man, 21 years old, readme was suffered from hepatitis B 14 years, existing Beijing academy postgraduate, and the hepatopathy training gene diagnosis of the People's Hospital, state, 26 Nikkei the southwest of Guizhou Province February in 2007 detects (checklist numbering: 07022604), the HBV-DNA positive, viral number are 14278774copies/ml.10000042), the HBV-DNA number is 7.73 * 10 February 28 began to take hepatitis B capsule of the present invention one month, (the invoice number: of the check on April 5th, 2007 to Haidian, Beijing hospital clinical after the drug withdrawal
5Copies/ml virus number descends 13505774, and the effect highly significant is still taken medicine continuing at present.
Patient king *, the woman, 19 years old, Guizhou university goes to school now, and for infected in the recent period, April 13 in 2005, Nikkei the southwest of Guizhou Province state institute of traditional Chinese medicine checked before clothes hepatitis B capsule of the present invention in readme, the HBV-DNA number is 2.93 * 107copies/ml, on July 20th, 2005 began to obey hepatitis B capsule of the present invention, Nikkei the southwest of Guizhou Province state institute of traditional Chinese medicine check Augusts 20 in 2005, viral number is 2.84 * 10
7Copies/ml virus number 900,000 copies/ml that descend take medicine to after August 20 October 2, and totally 42 days, in conjunction with hospital inspection, hepatitis B viruses (HBV)-DNA number was 5.06 * 10 through Yun Yan Chinese and Western, Kweiyang
6Copies/ml, virus descends 2.334 * 10
7Copies/ml amounts to a month virus and descends 1.7505 * 10
7Copies/ml.After continue to take medicine Yun Yan Chinese and Western, 31 Nikkei Kweiyang in 29 days to 2005 October in conjunction with hospital inspection, the HBV-DNA number is 2.46 * 10
5Copies/ml continued to take medicine one month subsequently, and readme HBV-DNA turns out cloudy, no longer took medicine also not see the HBV-DNA laboratory test report of turning out cloudy.
Patient Lee, the man, 50 years old, people from Kunming, readme was suffered from the hepatitis B disease 22 years, the check of First People's Hospital, JIUYUE 19 Nikkei Yunnan in 2005 clinical laboratory, the patient is a small three positive, the HBV-DNA number is 1.6 * 10
5Copies/ml uninterruptedly takes this medicine on August 21st, 2006, and (report: R2006082101024), the HBV-DNA number is 1381copies/ml is detected in molecular biosciences chamber, the 3rd the People's Hospital through the Kunming.Continue one month to 2006 JIUYUE 21 Nikkei Kunmings the 3rd the People's Hospital clinical laboratory immunity inspection of clothes subsequently, HBV-DN turns out cloudy.
The inventor inherited ancestors' meritorious achievements in 1997, since clinical drug treatment hepatitis B of the present invention, treat acute and chronic hepatitis B patient 30-40 people every year on average, the hundreds of people of hepatitis B patient that treat through the inventor over 10 years, general effect can both be controlled HBV-DNA and turn out cloudy, three months the shortest courses of treatment, 13 months the longest courses of treatment, not seeing has untoward reaction, does not appear malpractice one time, and the patient who has suffers from hepatitis B and reaches more than two decades and control not healing person, can both play good result once taking medicine of the present invention, medicine of the present invention is except that Fructus Xanthii has little poison, and all the other medicines all have no side effect, and no matter men and women, old and young are all suitable.
Claims (6)
1. the Chinese medicine that can treat hepatitis B is characterized in that it is the medicament of being made by the following weight parts proportion raw material:
Ramulus Uncariae Cum Uncis 40-63 Herb Polygoni Chinensis 5-8 Fructus Xanthii 5-8 Rhizoma Polygoni Cuspidati 5-10 Cortex Phellodendri 5-8 Herba Taxilli 5-13 Semen Maydis 11-14.
2. the Chinese medicine that can treat hepatitis B according to claim 1, wherein the weight portion proportioning of each raw material is:
Ramulus Uncariae Cum Uncis 51 Herb Polygoni Chinensiss 6.5 Fructus Xanthii 6.5 tiger branches 7 Cortex Phellodendris 6.5 Herba Taxillis 10 Semen Maydiss 12.5.
3. the Chinese medicine that can treat hepatitis B according to claim 1 and 2 is characterized in that said medicament is the above a dosage form of any pharmaceutics.
4. the Chinese medicine that can treat hepatitis B according to claim 3 is characterized in that said medicament is powder or piece agent.
5. according to claim 1 or the 2 or 4 described preparation method of Chinese medicine that can treat hepatitis B, it is characterized in that mixed powder is broken to the 60-80 order, sterilization treatment 10-30 minute, makes powder by the exsiccant raw material of prescription weighing.
6. the using method that can treat the medicine of hepatitis B according to claim 1 and 2, each dosage 1.4-1.6g that it is characterized in that being grown up, uses warm boiled water at every day three times.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007100777392A CN101041029B (en) | 2007-04-24 | 2007-04-24 | Chinese traditional medicine for curing hepatitis B |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007100777392A CN101041029B (en) | 2007-04-24 | 2007-04-24 | Chinese traditional medicine for curing hepatitis B |
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| Publication Number | Publication Date |
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| CN101041029A true CN101041029A (en) | 2007-09-26 |
| CN101041029B CN101041029B (en) | 2010-04-21 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2007100777392A Active CN101041029B (en) | 2007-04-24 | 2007-04-24 | Chinese traditional medicine for curing hepatitis B |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2353602A3 (en) * | 2009-08-07 | 2011-11-23 | Zheming Jin | Natural pharmaceutical preparations for increasing albumin |
| CN102697871A (en) * | 2012-06-06 | 2012-10-03 | 广西中医药大学 | Chinese herbal preparation with liver protecting and enzyme reducing effects and production method of same |
| CN103751462A (en) * | 2014-02-08 | 2014-04-30 | 刘方荣 | Traditional Chinese medicine tincture for treating wind-heat and blood dryness type steatorrhea dermatitis |
| CN104173443A (en) * | 2014-08-16 | 2014-12-03 | 黑龙江江恒医药科技有限公司 | Liver invigorating tablet and preparation method thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1044974C (en) * | 1994-06-17 | 1999-09-08 | 殷广全 | Anti- hepatitis B preparation |
| CN1151811C (en) * | 2001-01-04 | 2004-06-02 | 黄兆元 | Pain-relieving notoginseng mixture |
| CN1232270C (en) * | 2002-06-26 | 2005-12-21 | 李健勇 | Medicinal composition for treating liver cancer and pancreatic cancer and its preparing method |
-
2007
- 2007-04-24 CN CN2007100777392A patent/CN101041029B/en active Active
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2353602A3 (en) * | 2009-08-07 | 2011-11-23 | Zheming Jin | Natural pharmaceutical preparations for increasing albumin |
| CN102697871A (en) * | 2012-06-06 | 2012-10-03 | 广西中医药大学 | Chinese herbal preparation with liver protecting and enzyme reducing effects and production method of same |
| CN102697871B (en) * | 2012-06-06 | 2014-04-16 | 广西中医药大学 | Chinese herbal preparation with liver protecting and enzyme reducing effects and production method of same |
| CN103751462A (en) * | 2014-02-08 | 2014-04-30 | 刘方荣 | Traditional Chinese medicine tincture for treating wind-heat and blood dryness type steatorrhea dermatitis |
| CN104173443A (en) * | 2014-08-16 | 2014-12-03 | 黑龙江江恒医药科技有限公司 | Liver invigorating tablet and preparation method thereof |
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| Publication number | Publication date |
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| CN101041029B (en) | 2010-04-21 |
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