CN101028397A - Medicinal composition for treating traumatic skin coloboma, burn and scald and its production - Google Patents
Medicinal composition for treating traumatic skin coloboma, burn and scald and its production Download PDFInfo
- Publication number
- CN101028397A CN101028397A CNA2006100578089A CN200610057808A CN101028397A CN 101028397 A CN101028397 A CN 101028397A CN A2006100578089 A CNA2006100578089 A CN A2006100578089A CN 200610057808 A CN200610057808 A CN 200610057808A CN 101028397 A CN101028397 A CN 101028397A
- Authority
- CN
- China
- Prior art keywords
- weight portion
- radix
- weight
- sanguis draxonis
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
A Chinese medicine for treating traumatic skin defect, burn and scald is prepared from 11 Chinese-medicinal materials including turtle shell, honeysuckle flower, dandelion herb, liquorice root, etc.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, particularly relate to a kind of pharmaceutical composition for the treatment of traumatic skin coloboma and burn and scald.
Background technology
It is the surgical clinical commonly encountered diseases that burn and scald injures traumatic skin coloboma, also common in the orthopaedics; The doctor deals with comparatively thorny.Wound surface is undesirable, and free skin-grafting is difficult for surviving, patient's limitation of activity, and the course of disease is longer, is difficult to cure, easily infection and necrosis.Mostly used the kpetrolatum gauze dressing change behind the big whenever skin injury of patient in the past.Treat wound surface fresh back skin-grafting, the time is often long, painful big.Easily accompanying infection.
Summary of the invention
The object of the invention is to provide a kind of pharmaceutical composition that treatment traumatic skin coloboma and burn and scald is had remarkable result.
Another object of the present invention is to provide a kind of preparation of drug combination method for the treatment of traumatic skin coloboma and burn and scald.
The present invention is achieved through the following technical solutions: choose crude drug
Radix Angelicae Dahuricae 15-45 weight portion Carapax Trionycis 50-150 weight portion Spica Prunellae 20-60 weight portion
Flos Lonicerae 20-60 weight portion Herba Taraxaci 20-60 weight portion Radix Glycyrrhizae 25-75 weight portion
Sanguis Draxonis 10-30 weight portion Radix Arnebiae (Radix Lithospermi) 7-23 weight portion Cortex Cinnamomi 15-45 weight portion
Radix Rehmanniae Preparata 15-45 weight portion Fructus Gleditsia 10-30 weight portion
Pharmaceutical composition optimum ratio of the present invention is: choose crude drug
The Radix Angelicae Dahuricae 30 weight portion Carapax Trionycis 100 weight portion Spica Prunellaes 40 weight portions
Flos Lonicerae 40 weight portion Herba Taraxacis 40 weight portion Radix Glycyrrhizaes 50 weight portions
Sanguis Draxonis 20 weight portion Radix Arnebiae (Radix Lithospermi)s 15 weight portion Cortex Cinnamomis 30 weight portions
Radix Rehmanniae Preparata 30 weight portion Fructus Gleditsia 20 weight portions
Preparation of drug combination method of the present invention is: Sanguis Draxonis is ground into fine powder; Other medicines technology are routinely put in order immersion with 500-1500 weight portion Oleum sesami or are ground foam bubble 3-7 day, endure the degree of dripping into pearl to being concentrated to then, and following Sanguis Draxonis foam stirs evenly, descend adjuvant white beeswax 40-120 weight portion to dissolve turning off stove again, chilly one-tenth cream, after the bottling, 5-9 day gets final product in the boshing water.
Pharmaceutical composition of the present invention adds acceptable accessories and makes clinical acceptable exterior-applied formulation.
Described exterior-applied formulation is emplastrum, ointment, spray, tincture, water preparation or liniment etc.
Pharmaceutical composition of the present invention has removing the necrotic tissue and promoting granulation, the effect of the putrefaction removing of invigorating blood circulation, anti-inflammatory analgetic, skin moistening granulation promoting, and is remarkable to treatment traumatic skin coloboma and burn and scald effect.
Following experimental example is used to further specify the present invention:
1, clinical data
Among the 106 routine patients, male 56 examples, women 50 examples, the oldest person 66 years old, reckling 5 years old, 35 years old mean age, after the consultation time morbidity the shortest 15 minutes, the longest 30 days, wound area the maximum 10cm * 8cm ended, reckling 1cm * 0.5cm; The visible sclerotin of wound surface the darkest damaged person exposes, and the most shallow person reaches skin corium.Simple wound skin injury 40 examples, downright bad 26 examples, skin ulceration 42 examples of infecting after the debridement.
2, Therapeutic Method
Prescription: Radix Angelicae Dahuricae 30g, Carapax Trionycis 100g, Spica Prunellae 40g, Flos Lonicerae 40g, Herba Taraxaci 40g, Radix Glycyrrhizae 50g, Sanguis Draxonis 20g, Radix Arnebiae (Radix Lithospermi) 15g, Cortex Cinnamomi 30g, Radix Rehmanniae Preparata 30g, Fructus Gleditsia 20g.
Preparation method: Sanguis Draxonis is ground into fine powder; Other medicines technology routinely soak or ground the foam bubble 5 with 1000 gram Oleum sesami are whole, endure the degree of dripping into pearl to being concentrated to then, and following Sanguis Draxonis foam stirs evenly, and descends adjuvant white beeswax 80g to dissolve turning off stove again, chilly one-tenth cream, and after the bottling, in the boshing water 7 days
Using method: the bright wound surface of routine disinfection skin, thoroughly hemostasis, the gauze that will smoothen the present invention's " careless clever cream " after the debridement applies on wound surface, looks the wound surface exudate and changes dressings 1 time every 1～2 day.Should excise all sloughs for outmoded wound surface, apply again with the clever cream of the present invention's grass.The wound surface exudate does not more influence skin growth more yet in the process of changing dressings, this what is called " stewing pus and growing muscle ".Carefully see clearly the skin island on the wound surface when changing dressings, can not think the skin Supreme Being of having taken place by mistake the pus tongue and wipe away.
3, criterion of therapeutical effect
Cure: wound healing, nothing redness, nothing are oozed out and are suppurated, and no scar tissue and inflammatory granulation tissue form, and the concordant nothing boundary with normal surrounding tissue of wound surface can leave pigmentation;
Take a turn for the better: wound surface oozes out obvious minimizing, does not have red and swollen and suppuration, has the inflammatory granulation tissue to form, and wound surface is irregular, with surrounding tissue boundary is arranged;
Invalid: wound surface oozes out more, and redness or suppuration are arranged, and has the inflammatory granulation tissue to form, and wound surface and surrounding tissue boundary are obviously.
4, therapeutic outcome
Among the 106 routine patients, all recoveries from illness, treatment is rate 100% more, does not all have cicatrix after the healing.Healing time: the visible swelling sepage of wound surface in general 3-5 days, sepage in 5-10 days is decrescence few, as seen wound surface was repaired in 10-20 days, continue after wound surface heal gradually.
5, model case
Case 1: grandson * *, the woman, 47 years old, left hand squeeze to be hindered 5 days by oodle maker, back of the body palmar skin is irregular laceration, the edge cutaneous necrosis is about 15cm, the excision slough is coated with the present invention's " careless clever cream ", coating once a day, coating 14 times, finger stretch bend normal.
Case 2: in * *, man, 37 years old, motor-vehicle accident injury, right side instep portion was once successful in 2 skin-grafting of Certain Navy Yard hospital, the sky surplus in the of 40 of being in hospital, and wound surface 20 * 7cm is coated with the present invention's " careless clever cream ", behind the coating 18 times (18 days), the long 14 * 5cm swelling of wound disappears, and visible granulation growth is very fast.Behind the coating one month, wound all heals.
Case 3: the king * *, the woman, 47 years old, because of the right side breast carcinoma in the hospitalize of Beijing main forces, carry out behind the radical correction surplus in the of 40 day the notching edge cutaneous necrosis.Excise slough in here on one side, Yi Bian be coated with the present invention " careless clever cream ", treat 28 altogether, thoroughly cicatrix is not stayed in healing.
Following embodiment is used to further specify the present invention:
Embodiment 1
Radix Angelicae Dahuricae 30kg Carapax Trionycis 100kg Spica Prunellae 40kg Flos Lonicerae 40kg
Herba Taraxaci 40kg Radix Glycyrrhizae 50kg Sanguis Draxonis 20kg Radix Arnebiae (Radix Lithospermi) 15kg
Cortex Cinnamomi 30kg Radix Rehmanniae Preparata 30kg Fructus Gleditsia 20kg
Sanguis Draxonis is ground into fine powder; Other medicines technology are routinely put in order immersion or were ground the foam bubble 5 with 1000 gram Oleum sesami, endure the degree of dripping into pearl to being concentrated to then, and following Sanguis Draxonis foam stirs evenly, and descends adjuvant white beeswax 80g to dissolve turning off stove again, and chilly one-tenth cream after the bottling, got final product in the boshing water on the 7th.
Embodiment 2
Radix Angelicae Dahuricae 20kg Carapax Trionycis 130kg Spica Prunellae 30kg Flos Lonicerae 50kg
Herba Taraxaci 30kg Radix Glycyrrhizae 65kg Sanguis Draxonis 15kg Radix Arnebiae (Radix Lithospermi) 20kg
Cortex Cinnamomi 20kg Radix Rehmanniae Preparata 40kg Fructus Gleditsia 15kg
Said medicine technology is routinely made spray.
Embodiment 3
Radix Angelicae Dahuricae 40kg Carapax Trionycis 70kg Spica Prunellae 50kg Flos Lonicerae 30kg
Herba Taraxaci 50kg Radix Glycyrrhizae 35kg Sanguis Draxonis 25kg Radix Arnebiae (Radix Lithospermi) 10kg
Cortex Cinnamomi 40kg Radix Rehmanniae Preparata 20kg Fructus Gleditsia 25kg
Said medicine technology is routinely made tincture.
Embodiment 4
Radix Angelicae Dahuricae 30kg Carapax Trionycis 100kg Spica Prunellae 40kg Flos Lonicerae 40kg
Herba Taraxaci 40kg Radix Glycyrrhizae 50kg Sanguis Draxonis 20kg Radix Arnebiae (Radix Lithospermi) 15kg
Cortex Cinnamomi 30kg Radix Rehmanniae Preparata 30kg Fructus Gleditsia 20kg
Said medicine technology is routinely made ointment.
Embodiment 5
Radix Angelicae Dahuricae 20kg Carapax Trionycis 130kg Spica Prunellae 30kg Flos Lonicerae 50kg
Herba Taraxaci 30kg Radix Glycyrrhizae 65kg Sanguis Draxonis 15kg Radix Arnebiae (Radix Lithospermi) 20kg
Cortex Cinnamomi 20kg Radix Rehmanniae Preparata 40kg Fructus Gleditsia 15kg
Said medicine technology is routinely made liniment.
Embodiment 6
Radix Angelicae Dahuricae 40kg Carapax Trionycis 70kg Spica Prunellae 50kg Flos Lonicerae 30kg
Herba Taraxaci 50kg Radix Glycyrrhizae 35kg Sanguis Draxonis 25kg Radix Arnebiae (Radix Lithospermi) 10kg
Cortex Cinnamomi 40kg Radix Rehmanniae Preparata 20kg Fructus Gleditsia 25kg
Said medicine technology is routinely made water preparation.
Claims (10)
1, a kind of pharmaceutical composition for the treatment of traumatic skin coloboma and burn and scald is characterized in that said composition is to be made by following crude drug:
Radix Angelicae Dahuricae 15-45 weight portion Carapax Trionycis 50-150 weight portion Spica Prunellae 20-60 weight portion
Flos Lonicerae 20-60 weight portion Herba Taraxaci 20-60 weight portion Radix Glycyrrhizae 25-75 weight portion
Sanguis Draxonis 10-30 weight portion Radix Arnebiae (Radix Lithospermi) 7-23 weight portion Cortex Cinnamomi 15-45 weight portion
Radix Rehmanniae Preparata 15-45 weight portion Fructus Gleditsia 10-30 weight portion.
2, pharmaceutical composition according to claim 1 is characterized in that said composition is to be made by following crude drug:
The Radix Angelicae Dahuricae 30 weight portion Carapax Trionycis 100 weight portion Spica Prunellaes 40 weight portions
Flos Lonicerae 40 weight portion Herba Taraxacis 40 weight Radix Glycyrrhizaes 50 weight portions
Sanguis Draxonis 20 weight portion Radix Arnebiae (Radix Lithospermi)s 15 weight portion Cortex Cinnamomis 30 weight portions
Radix Rehmanniae Preparata 30 weight portion Fructus Gleditsia 20 weight portions.
3, pharmaceutical composition according to claim 1 is characterized in that said composition is to be made by following crude drug:
The Radix Angelicae Dahuricae 20 weight portion Carapax Trionycis 130 weight portion Spica Prunellaes 30 weight portions
Flos Lonicerae 50 weight portion Herba Taraxacis 30 weight portion Radix Glycyrrhizaes 65 weight portions
Sanguis Draxonis 15 weight portion Radix Arnebiae (Radix Lithospermi)s 20 weight portion Cortex Cinnamomis 20 weight portions
Radix Rehmanniae Preparata 40 weight portion Fructus Gleditsia 15 weight portions.
4, pharmaceutical composition according to claim 1 is characterized in that said composition is to be made by following crude drug:
The Radix Angelicae Dahuricae 40 weight portion Carapax Trionycis 70 weight portion Spica Prunellaes 50 weight portions
Flos Lonicerae 30 weight portion Herba Taraxacis 50 weight portion Radix Glycyrrhizaes 35 weight portions
Sanguis Draxonis 25 weight portion Radix Arnebiae (Radix Lithospermi)s 10 weight portion Cortex Cinnamomis 40 weight portions
Radix Rehmanniae Preparata 20 weight portion Fructus Gleditsia 25 weight portions.
5,, it is characterized in that this method is according to the described preparation of drug combination method of one of claim 1-4:
Sanguis Draxonis is ground into fine powder; Other medicines technology are routinely put in order immersion with 500-1500 weight portion Oleum sesami or are ground foam bubble 3-7 day, endure the degree of dripping into pearl to being concentrated to then, and following Sanguis Draxonis foam stirs evenly, descend adjuvant white beeswax 40-120 weight portion to dissolve turning off stove again, chilly one-tenth cream, after the bottling, 5-9 day gets final product in the boshing water.
6, preparation of drug combination method according to claim 5 is characterized in that this method is:
Sanguis Draxonis is ground into fine powder; Other medicines technology are routinely put in order immersion or were ground the foam bubble 5 with 1000 weight portion Oleum sesami, endure the degree of dripping into pearl to being concentrated to then, and following Sanguis Draxonis foam stirs evenly, and descends adjuvant white beeswax 80 weight portions to dissolve turning off stove again, and chilly one-tenth cream after the bottling, got final product in the boshing water on the 7th.
7,, it is characterized in that adding the adjuvant of pharmaceutically accepting and make the exterior-applied formulation of clinical acceptance according to the described pharmaceutical composition of one of claim 1-4.
8, the exterior-applied formulation of pharmaceutical composition according to claim 7 is characterized in that described exterior-applied formulation is emplastrum, ointment, spray, tincture, water preparation or liniment.
9, according to the application of the described pharmaceutical composition of one of claim 1-4 in the medicine of preparation treatment traumatic skin coloboma.
10, according to the application of the described pharmaceutical composition of one of claim 1-4 in the medicine of preparation treatment burn and scald.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100578089A CN100479838C (en) | 2006-02-27 | 2006-02-27 | Medicinal composition for treating traumatic skin coloboma, burn and scald and preparation thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100578089A CN100479838C (en) | 2006-02-27 | 2006-02-27 | Medicinal composition for treating traumatic skin coloboma, burn and scald and preparation thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101028397A true CN101028397A (en) | 2007-09-05 |
| CN100479838C CN100479838C (en) | 2009-04-22 |
Family
ID=38714050
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2006100578089A Expired - Fee Related CN100479838C (en) | 2006-02-27 | 2006-02-27 | Medicinal composition for treating traumatic skin coloboma, burn and scald and preparation thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100479838C (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105031287A (en) * | 2015-09-18 | 2015-11-11 | 全椒先奇医药科技有限公司 | Traditional Chinese medicine ointment for treating scalds |
| CN108498662A (en) * | 2017-12-22 | 2018-09-07 | 王修丽 | A kind of Orthopaedic nursing cleaning Chinese medicine |
-
2006
- 2006-02-27 CN CNB2006100578089A patent/CN100479838C/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105031287A (en) * | 2015-09-18 | 2015-11-11 | 全椒先奇医药科技有限公司 | Traditional Chinese medicine ointment for treating scalds |
| CN108498662A (en) * | 2017-12-22 | 2018-09-07 | 王修丽 | A kind of Orthopaedic nursing cleaning Chinese medicine |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100479838C (en) | 2009-04-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1268365C (en) | Ointment for treating burns and scalds and its preparation | |
| CN105535334A (en) | Radix arnebiae and milkvetch root granulation-promoting extract and preparation method | |
| CN108186711A (en) | Promote the pharmaceutical composition of wound healing | |
| CN104940905A (en) | Medicine composition for promoting wound healing after operation and preparation method thereof | |
| CN106692307B (en) | Hydrogel for treating female cervical erosion and preparation method thereof | |
| CN101264196B (en) | Externally-applied medicinal composition for treating surgical wound and preparation of ointment thereof | |
| CN113197844A (en) | Scar-free tissue regeneration promoting paste | |
| CN105213637A (en) | A kind of for epidemic victim's wound disinfection nursing powder and preparation method thereof | |
| CN100350921C (en) | Dermatosis eliminating medicine | |
| CN101028397A (en) | Medicinal composition for treating traumatic skin coloboma, burn and scald and its production | |
| CN101797286B (en) | Chinese traditional medicine combination for alleviating wound infections and suture reaction after surgery and preparation method thereof | |
| CN112190660A (en) | Traditional Chinese medicine composition for promoting wound healing and preparation method thereof | |
| CN112156225A (en) | Chitosan or and algal polysaccharide composite biological matrix liquid dressing gel preparation and preparation method thereof | |
| CN1939470A (en) | Chinese medicinal plaster with analgetic, hemostatic repercussive and sore-arresting functions | |
| CN105233258A (en) | Composition for removing acne | |
| CN1242773C (en) | Medicine for treating skin wound and its processing method | |
| CN105748619B (en) | Medicine for treating plasma cell mastitis and preparation method thereof | |
| CN1939488A (en) | Externally-applied ointment for treating subcutaneous abscess and its preparation | |
| CN1261128C (en) | Medicine for treating burn and scald, preparing method thereof | |
| CN103816268B (en) | A kind of traditional Chinese herb medicine and manufacture method thereof for the treatment of burn and scald | |
| CN1236798C (en) | External medicine for treating bone tuberculosis | |
| CN1275623C (en) | Green peach hull and psoralea fruit containing liquor for treating leucoderma and alphos | |
| CN104138522A (en) | Crack healing ointment | |
| CN101647851B (en) | Medicament for treating burn and scald and preparation method thereof | |
| CN101564426A (en) | Medicament for external use for treating onychomycosis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: SUN GUANGQIANG Effective date: 20140411 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| C53 | Correction of patent for invention or patent application | ||
| CB03 | Change of inventor or designer information |
Inventor after: Sun Linjun Inventor after: Sun Guangqiang Inventor before: Sun Linjun |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: SUN LINJUN TO: SUN LINJUN SUN GUANGQIANG |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20140411 Address after: 266100 Department of surgery, the Eighth People's Hospital of Shandong, Qingdao Patentee after: Sun Linjun Patentee after: Sun Guangqiang Address before: 266100 Department of surgery, the Eighth People's Hospital of Shandong, Qingdao Patentee before: Sun Linjun |
|
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20090422 Termination date: 20200227 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |