CN101027407B - 检测突变的方法 - Google Patents

检测突变的方法 Download PDF

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Publication number
CN101027407B
CN101027407B CN2003801014694A CN200380101469A CN101027407B CN 101027407 B CN101027407 B CN 101027407B CN 2003801014694 A CN2003801014694 A CN 2003801014694A CN 200380101469 A CN200380101469 A CN 200380101469A CN 101027407 B CN101027407 B CN 101027407B
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CN
China
Prior art keywords
sequence
primer
seq
detect
sudden change
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Expired - Fee Related
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CN2003801014694A
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English (en)
Chinese (zh)
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CN101027407A (zh
Inventor
金楠根
金锡俊
金寿玉
金恩玉
文明顺
刘王敦
李昌弘
郑贤在
池美善
黄圣奎
洪璿杓
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Genematrix Inc
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Genematrix Inc
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Publication date
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Priority claimed from PCT/KR2003/002179 external-priority patent/WO2004035832A1/en
Publication of CN101027407A publication Critical patent/CN101027407A/zh
Application granted granted Critical
Publication of CN101027407B publication Critical patent/CN101027407B/zh
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/706—Specific hybridization probes for hepatitis
    • C12Q1/707—Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN2003801014694A 2002-10-18 2003-10-17 检测突变的方法 Expired - Fee Related CN101027407B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
KR1020020063832 2002-10-18
KR10-2002-0063832 2002-10-18
KR20020063832 2002-10-18
KR10-2003-0061066 2003-09-02
KR1020030061066 2003-09-02
KR20030061066A KR100642829B1 (ko) 2002-10-18 2003-09-02 염기변이 분석방법
PCT/KR2003/002179 WO2004035832A1 (en) 2002-10-18 2003-10-17 Method for detecting mutations

Related Child Applications (2)

Application Number Title Priority Date Filing Date
CN200910207600.4A Division CN101824465B (zh) 2002-10-18 2003-10-17 用于分析基因突变的引物
CN2009102088016A Division CN101962672A (zh) 2002-10-18 2003-10-17 检测突变的方法

Publications (2)

Publication Number Publication Date
CN101027407A CN101027407A (zh) 2007-08-29
CN101027407B true CN101027407B (zh) 2012-05-23

Family

ID=32464416

Family Applications (3)

Application Number Title Priority Date Filing Date
CN200910207600.4A Expired - Fee Related CN101824465B (zh) 2002-10-18 2003-10-17 用于分析基因突变的引物
CN2009102088016A Pending CN101962672A (zh) 2002-10-18 2003-10-17 检测突变的方法
CN2003801014694A Expired - Fee Related CN101027407B (zh) 2002-10-18 2003-10-17 检测突变的方法

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CN200910207600.4A Expired - Fee Related CN101824465B (zh) 2002-10-18 2003-10-17 用于分析基因突变的引物
CN2009102088016A Pending CN101962672A (zh) 2002-10-18 2003-10-17 检测突变的方法

Country Status (4)

Country Link
JP (2) JP4020845B2 (ja)
KR (1) KR100642829B1 (ja)
CN (3) CN101824465B (ja)
HK (1) HK1113589A1 (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009201457A (ja) * 2008-02-29 2009-09-10 Jsr Corp プライマーとプローブとのセット、リアルタイム検出ｐｃｒ法によるｃ型肝炎ウイルスｒｎａ検出用キット、ならびにリアルタイム検出ｐｃｒ法によるｃ型肝炎ウイルスｒｎａの検出方法
CN101597638B (zh) * 2008-06-04 2011-12-28 博奥生物有限公司 一种检测基因多突变位点的方法及其专用试剂盒
KR101025450B1 (ko) * 2008-08-06 2011-04-04 (주)진매트릭스 다중 염기변이 분석방법
KR101287431B1 (ko) * 2010-05-07 2013-07-19 (주)진매트릭스 표적 유전자의 다양한 변이가 존재하는 유전자 영역을 증폭하기 위한 프라이머 조성물, 이를 이용한 표적 유전자 증폭 방법 및 이를 포함하는 ｐｃｒ 증폭 키트 그리고 이를 이용한 표적 유전자의 유전자형 분석방법
KR20130110811A (ko) * 2012-03-30 2013-10-10 (주)진매트릭스 제한효소 절편 질량다형성법을 이용하여 ｈｉｖ에 대한 약제 내성 유전자 돌연변이 검출방법
KR101915701B1 (ko) * 2016-06-16 2018-11-07 한국한의학연구원 돌연변이 발생률의 측정 방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1340705A (zh) * 2000-08-25 2002-03-20 程新建 一种检测等位基因点突变的方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Georgios Amexis等.Quantitative mutant analysis of viral quasispecies by chip-based matrix-assisted laser desorptiony ionization time-of-flight mass spectrometry.《PNAS》.2001,第98卷(第21期),12097–12102. *
Kenneth H. Buetow等.High-throughput development and characterization of a genomewide collection of gene-based single nucleotide polymorphism markers by chip-based matrix-assisted laser desorptionyionization time-of-flight mass spectrometry.《PNAS》.2001,第98卷(第2期),581–584. *

Also Published As

Publication number Publication date
JP4073471B2 (ja) 2008-04-09
JP2007209354A (ja) 2007-08-23
JP2004135659A (ja) 2004-05-13
CN101027407A (zh) 2007-08-29
CN101824465B (zh) 2012-12-19
HK1113589A1 (en) 2008-10-10
JP4020845B2 (ja) 2007-12-12
KR100642829B1 (ko) 2006-11-10
CN101962672A (zh) 2011-02-02
KR20040034382A (ko) 2004-04-28
CN101824465A (zh) 2010-09-08

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