CN101023988B

CN101023988B - Chinese medicine preparation for treating infant's diarrhea

Info

Publication number: CN101023988B
Application number: CN2006100424697A
Authority: CN
Inventors: 史静; 陈新
Original assignee: Individual
Current assignee: Individual
Priority date: 2006-02-22
Filing date: 2006-02-22
Publication date: 2011-07-27
Anticipated expiration: 2026-02-22
Also published as: CN101023988A

Abstract

The present invention relates to a Chinese medicine preparation for curing infantile diarrhea. Said Chinese medicine preparation is made from pure Chinese medicinal materials, and can be made into two preparations of decoction preparation and belly-button adhesive plaster preparation, which are made from Chinese medicinal materials. The Chinese medicine preparation has the advantage of convenient material drawing, convenient administration, and no need of special raw material. The Chinese medicine preparation of the invention can effective for curing infantile diarrhea, is a pure Chinese medicine preparation, and has no obvious toxicity or side effect. The invention is used for curing infantile diarrhea in Chinese medicine field.

Description

The Chinese medicine preparation of treatment infantile diarrhea

Technical field

The invention belongs to the field of Chinese medicines, the Chinese medicine preparation of the treatment infantile diarrhea that particularly a kind of pure Chinese medicine is made.

Background technology

Past is one of high disease of infant sickness rate in period, also is one of major reason of infant death.Through research for many years both at home and abroad, strengthen prevention, improved treatment level, it is less to fall ill in recent years, and the state of an illness is also lighter, but still is the modal digestive tract syndrome of China's infant.Show as times of defecation and increase, every day is for several times surplus 10 time.It is rare to defecate, and low amounts of water is arranged sometimes, is yellow or yellow green, is mixed with a small amount of mucus.Each amount is few, common white or faint yellow fritter.Severe patient excrement piece disappears and is water sample or egg soup sample.Normal or the heating of body temperature.Because the cause of disease of infantile diarrhea is many-sided, the Therapeutic Principle of doctor trained in Western medicine is with suitable rest to digestive tract; The control intestinal is inside and outside to be infected; Good nursing care.But therapeutic effect is unsatisfactory.Also there is many clinicians Chinese medicine powder on probation to give the umbilicus external application, the treatment of infantile diarrhea is had certain curative effect, but effect is still undesirable.

Summary of the invention

The object of the present invention is to provide a kind of Chinese medicine preparation that can effectively treat infantile diarrhea.

The present invention is achieved in that

The Chinese medicine preparation of treatment infantile diarrhea is characterized in that it being two kinds of preparations that the Chinese medicine by following weight parts is made:

1, decoction: the Radix Astragali 2, Cortex Cinnamomi 2, Flos Caryophylli 2, Fructus Foeniculi 2, Herba Portulacae 5 are decocted in water for oral dose every day 2 times (can add a small amount of seasoning of Mel).

2, umbilicus externally dressing: the Radix Astragali 5, Cortex Cinnamomi 3, Flos Caryophylli 5, Fructus Foeniculi 5, Herba Portulacae (doing) 5 above-mentioned Chinese medicines are pulverized to be fixed in the cloth bag of packing into and are aligned in sick child's umbilicus.Changed potion on the 3rd.

After the present invention adopts above-mentioned prescription, have following clinical effectiveness:

1, effectively treat infantile diarrhea, total effective rate is up to 93.66%.

2, convenient drug administration.

3, pure Chinese medicinal preparation, no obvious toxic-side effects.

The present invention is made for pure Chinese medicine, and pharmacological research proves:

The Radix Astragali: tonifying Qi and lifting yang is with controlling cards such as the deficiency of vital energy, lack of appetite, loose stool.This product contains saccharide, choline, betanin, several aminoacid etc.Various bacteria there is antibacterial action.

Cortex Cinnamomi: warming middle-JIAO YANG invigorating, cold relieving pain relieving are cold with controlling lower abdomen, and deficiency of spleen-YANG and kidneyYANG stomachache is had loose bowels.Cortex Cinnamomi mainly contains Oleum Cinnamomi.Gastrointestinal there is the abirritate effect, can strengthens digestive function, get rid of the digestive tract pneumatosis, alleviate gastrointestinal convulsion.The blood vessel dilating effect is arranged, strengthen blood circulation.Dysentery bacterium there is inhibitory action.

Flos Caryophylli: warming middle-JIAO to send down the adverse QI, pain relieving cure mainly coldness and pain in the epigastrium, and vomiting is had loose bowels.Containing volatile oil is Oleum Caryophylli.Its leachate can significantly increase gastric acid output and peptic activity of stomach.Bacillus pestis, vibrio cholera, anthrax bacillus, dysentery bacterium, escherichia coli there is inhibitory action.

Fructus Foeniculi: promoting the circulation of QI to relieve pain, stomach function regulating, the warm liver of the kidney warming cure mainly colic of cold type stomachache, lack of appetite and vomiting.Main volatile oil component is trans-anethole, limonene, and enterokinesia is had facilitation, and the Cavia porcellus smooth muscle is had relexation.Fungal spore, coccus, bacillus there is sterilization functions.

Herba Portulacae: clearing away heat to cure dysentery Herba Portulacae stem and leaf contains nicotinic acid, Saponin, tannin, carbamide etc., and broad-spectrum antibacterial action is arranged, and dysentery, typhoid fever etc. is had effect preferably.Experiment in vitro, Herba Portulacae has inhibition or killing action to various dysentery bacterium.Clinical report, Herba Portulacae all have good result to various bacterial dysentery and suppurative illness.

Think that at present the infantile diarrhea cause of disease is many-sided causing such as physical factors, infective agent, digestive functional disturbance.Treatment comprises dietetic therapy and fluid therapy.The traditional Chinese medical science thinks that the strong then digestion of " basis of letting out is invariably because taste " taste is normal.If intemperance of taking food, changes in temperature imbalance, or being invaded by exogenous pathogen cause transporting and transforming function of the spleen and stomach not normal, form and have loose bowels.At this situation, in the present invention prescription in the fill temperature Radix Astragali, the Cortex Cinnamomi of yang invigorating be principal agent, in the hope of reaching antibiotic, strengthen digestive function, alleviating the main purpose of gastrointestinal convulsion.Flos Caryophylli, Fructus Foeniculi warming middle-JIAO stopping leak are removed smooth muscle spasm simultaneously.Herba Portulacae heat clearing away sterilization.

For verifying therapeutic effect of the present invention, the present invention has carried out following clinical experiment in 2004-2005 Shandong Province's Liaocheng City second people:

1. data and method

1.1 clinical data: test infantile diarrhea sick child 124 examples altogether, wherein male 73 examples, women 51 examples.6 months ages-18 month.All case all meets the diagnostic criteria of infantile diarrhea.Case grouping: get 63 examples, be equipped with medicine of the present invention and treat, be the treatment group; Other 61 example is a matched group, treats with conventional method.Two groups of patients' clinical manifestation has comparability preferably.Two groups of ages, sex, severity extent, observing time the tool comparability.

1.2 method: the treatment group adopts the invention medicine to treat treatment time and was generally 4-6 days.Matched group adopts conventional therapy, and promptly dioctahedral smectite is oral,＜1 years old 1 gram every day 3 times;＜2 years old 1.5 gram every days 3 times; 2 years old 3 gram every day 3 times; Suspect joining and virazole 10-15 milligram/kilogram/day, intravenous drip of rotavirus infection.If with water, electrolyte disturbance all to supplementing water, electrolyte.

1.3 the effect criterion produce effects of treatment infantile diarrhea: treatment back diarrhoea transference cure; Effectively: times of defecation reduces, and the stool character is improved; Invalid: the original symptom of diarrhea in treatment back does not have improvement.

2. result

Treatment is observed after organizing the patient of 63 routine infantile diarrheas, and the result is obvious effective rate 79.37% (50 example), effective percentage 14.29% (9 example), inefficiency 6.35% (4 example).Obvious effective rate, total effective rate are apparently higher than matched group 48%, 68% (all p＜0.01) (seeing the following form).In the treatment group, the application invention medicine is treated and just can be seen that times of defecation reduced in general 36 hours, and the stool beginning becomes pasty state until shaping by water sample.Infant does not have significant discomfort.

The example number

Produce effects (%)

Effectively (%)

Invalid (%)

Total effective rate (%)

The treatment group	63	50(79.37)	9(14.29)	4(6.35)	93.66
						Matched group	61	35(57.38)	9(14.75)	17(27.87)	72.13

Obvious effective rate, total effective rate are compared equal p＜0.01 with matched group

Above-mentioned experimental results show that: the present invention is fine to treatment infantile diarrhea effect, and oral Chinese medicine dosage seldom and can add a small amount of seasoning of Mel; The Traditional Chinese Medicine for external application medicated bag, infant does not have any discomfort, does not influence the daily life of infant.

The specific embodiment

Below in conjunction with example medicine of the present invention is elaborated:

1, Orally-administered decoction: get the Radix Astragali 2, Cortex Cinnamomi 2, Flos Caryophylli 2, Fructus Foeniculi 2, Herba Portulacae 5 waters and decoct, successively boil 2 times, boiled first 20 minutes, boil for the 2nd time get final product in 15 minutes, and 2 times decocting liquid is converted together, and totally 40 milliliters, the cold preservation of bottling is standby.Each 3-5 milliliter during clothes, was obeyed 3-5 days altogether at every day 2 times (can add a small amount of seasoning of Mel).

2, umbilicus externally dressing: get the Radix Astragali 5, Cortex Cinnamomi 3, Flos Caryophylli 5, Fructus Foeniculi 5, Herba Portulacae (doing) 5 above-mentioned Chinese medicines and pulverize in the cloth bag of packing into (above-mentioned amount is 1 bag dosage) being fixed is aligned in sick child's umbilicus.Change potion on 3rd, and wore 2 bags altogether.

Above-mentioned two kinds of methods are used in combination simultaneously can effectively treat infantile diarrhea.

Below for utilizing the concrete case of Drug therapy of the present invention:

Example 1, grandson so-and-so, man, 7 months.Came Liaocheng City second the People's Hospital in Shandong Province's to receive treatment on August 18th, 2004 in 3 days because of suffering from diarrhoea.Have a medical check-up: T37.3 ℃ of spirit can, the cardiopulmonary Non Apparent Abnormality of having a medical check-up, abdominal part is smooth, abdomen is soft, does not touch enclosed mass, Immobility voiced sound, bowel sounds active.The stool routine examination inspection is shown: watery stool has lipochondrion, no erythrocyte.Diagnosis: infantile diarrhea.Use the inventive method treatment totally 5 days, patient's recovery from illness.

Example 2, the flood certain, woman, 11 months.Came Liaocheng City second the People's Hospital in Shandong Province's to receive treatment on October 23rd, 2005 in 2 days because of suffering from diarrhoea.Have a medical check-up: T37.3 ℃ of spirit can, the cardiopulmonary Non Apparent Abnormality of having a medical check-up, abdominal part is smooth, abdomen is soft, does not touch enclosed mass, Immobility voiced sound, bowel sounds active.The stool routine examination inspection is shown: the scattered paste shape stool has lipochondrion, no erythrocyte.Diagnosis: infantile diarrhea.Use the inventive method treatment totally 5 days, patient's recovery from illness.

Claims

1. Chinese medicine preparation for the treatment of infantile diarrhea is characterized in that it being that Chinese medicine by following weight parts is made:

(1) decoction: the Radix Astragali 2, Cortex Cinnamomi 2, Flos Caryophylli 2, Fructus Foeniculi 2, Herba Portulacae 5, be decocted in water for oral dose every day twice, add Mel 6 gram seasonings;

(2) umbilicus externally dressing: the Radix Astragali 5, Cortex Cinnamomi 3, Flos Caryophylli 5, Fructus Foeniculi 5, Herba Portulacae 5, above-mentioned Chinese medicine are pulverized to be fixed in the cloth bag of packing into and are aligned in sick child's umbilicus, replacing potion on the 3rd.