CN101013084A - Optical path system of clinical inspection analytic instrument - Google Patents

Abstract

The invention relates to an optical system of medical examination and analysis equipment, particularly to micro monochromator as a medical examination and analysis equipment of prismatic system. The invention includes the light source module with radiation continuous spectrum, the filter module for eliminating miscellaneous light and second level diffraction spectra, the micro monochromator with tunable continuous wavelength, the constant temperature groove module, the optoelectronic receiver module, and it is characterized by that the said light source module emits the composite light, through the said filter module, filtering not related spectrum, focusing on the entry slit of the micro monochromator, and from the out slit of the micro monochromator, emitting the required monochromatic light, and the monochromatic light passes the said constant temperature groove module to take colorimetry, and finally, the said photoelectric receiver module receives it. Compared with the existing technology, this invention uses modular and component formation to design the whole optical system, the whole optical system divided into several modules, and used component formation in the module design, so it has advantages that debug staff facilitates assembly and debugging.

Description

The light path system of clinical inspection analytic instrument

Technical field

The present invention relates to a kind of light path system of medical inspection analytical instrument, particularly relate to the medical inspection analytical instrument of miniature monochromator as medical inspection analytical instrument beam splitting system.

Technical background

Optical Analysis Method is as one of detection means the most frequently used in the clinical treatment check analysis, and wherein photoelectric colorimetry and spectrophotometric method are the most outstanding, has been widely used in the multiple medical analysis instrument, as Biochemical Analyzer, microplate reader, enzyme is exempted from, blood clotting, and susceptibility equipment.The speciality that colourimetry and spectrophotometric method are based on different molecular structures absorbs the selectivity of electromagnetic radiation and the analytical approach set up.This analytical approach realizes prerequisite is exactly how to produce required radiation wavelength, also is monochromatic light.Producing monochromatic method has varied, require and the application scenario according to different accuracy, the realization technology has at present: the 1ed monochromatic source, the interference filter light splitting technology, prismatic decomposition technology and grating beam splitting technology, wherein interference filter light splitting technology and grating beam splitting technology can realize that monochromatic precision is higher, and promptly spectral bandwidth can both be less than 12nm, so these two kinds of technology satisfy the requirement of clinical examination instrument fully.At the clinical examination instrument, as Biochemical Analyzer and enzyme micro-plate reader, great majority use the interference filter light splitting technology to produce monochromatic wavelength.This light channel structure is simple, is fit to various small-sized check analysis instruments.But it has shortcoming, and the interference filter life-span is short, needs often to change.In addition, the monochromatic wavelength number is limited, the corresponding wavelength of optical filter, and situation can only be assembled 8 optical filters, maximum 12 optical filters mostly.Occasion for special wavelength needs then need increase and join respective wavelength.And the beam splitting system of employing grating beam splitting technology is commonly referred to as monochromator, can realize that then wavelength is adjustable continuously, promptly in using spectral range, can realize that the wavelength of 1nm stepping is selected.Monochromator is a hermetic type in addition, moisture-sensitive not, and the life-span is more than 2 years.

The grating beam splitting technology has been widely applied to large-scale high-accuracy spectrophotometer as a kind of mature technology day by day, but less relatively in the application of conventional medical inspection equipment.In recent years, the designer just begins to consider this technology is applied to conventional medical inspection instrument.On spectrophotometer, often can meet the Cerny-Turner light channel structure, two kinds of light channel structures of Fastie-Ebert light channel structure.The Cerny-Turner light channel structure be by two independently concave mirror collimate and focused beam.And in the Fastie-Ebert light channel structure, then be the synthetic a slice of these two concave mirrors, play collimation and focusing function simultaneously.The Cerny-Turner light channel structure is fit to wavelength accuracy and the strict occasion of aberration.And the Fastie-Ebert light channel structure also can be used on the higher occasion of wavelength accuracy, but its aberration is bigger.For the routine clinical testing instruments, can allow wavelength bandwidth less than 12nm, and can allow bigger aberration, so the Fastie-Ebert light channel structure relatively is suitable for miniature instrument, as Biochemical Analyzer.

On the market, the producer of existing a few production clinical examination instrument uses the light channel structure of grating beam splitting at home.In order to dwindle light channel structure and to simplify light path system, they adopt concave reflection grating, but because the concave reflection grating incisure density is less than normal, generally under 1200L/mm, again because require spectral bandwidth less than 12nm, therefore the focal length that cooperates with the incisure density of 1200L/mm must be more than 90mm, and the therefore final light channel structure size that realizes is bigger, causes last instrument moulding bigger than normal.In addition, disqualification rate is higher in the making of concave reflection grating, causes the concave grating cost higher.Adopt the plane reflection grating to realize that beam split then is more common grating beam splitting mode, it needs concave mirror to cooperate.Also simple relatively on manufacture craft, percent of pass is higher.

For the continuously adjustable grating beam splitting mode of wavelength, according to grating equation,

$2\sin \left(\frac{\mathrm{\α}+\mathrm{\β}}{2}\right)\cos \left(\frac{\mathrm{Dv}}{2}\right)={10}^{16}*\mathrm{Kn\λ}$

Need to adopt sine mechanism to realize the sinusoidal variations of above-mentioned equation.So-called sinusoidal variations is exactly to realize the sinusoidal variations of wavelength and grating corner, and the general gearing structure of precision that adopts realizes this function.But in implementation, each is variant.Great majority are to increase structure, and the feed screw nut is carried out spacing on the surface level, move steadily to guarantee the feed screw nut, and in addition,, also be to differ bigger to the origin position detection of precision drive mechanism.In the present invention, then be to utilize existing structure to realize feed screw nut's surface level upper limit.In addition, in some light path systems, guarantee wavelength accuracy by origin position and the outside stepper motor of surveying the feed screw nut, the present invention surveys the initial point of grating turntable and stepper motor to guarantee wavelength accuracy, improves the confidence level of surveying.

The debugging of monochromator is quite loaded down with trivial details, comprises the debugging of each eyeglass hot spot, the debugging of wavelength accuracy and the debugging of origin position.Each step examination all needs relevant tool just can finish, and requires the commissioning staff to have certain professional skill.Along with the needs to the clinical examination instrument that adopts grating beam splitting constantly increase, require the commissioning staff to finish the debugging of some light paths at the appointed time.Therefore in the whole optical path system design, comprise the structural design of miniature monochromator, need take into full account and how reduce debugging work load and improve debugging speed.

In order to overcome the deficiencies in the prior art, in the present invention, adopt modularization and kit form to design a whole set of light path system, promptly a whole set of light path system is divided into several modules, adopts the kit form design in module, makes things convenient for the commissioning staff to assemble and debugs.

Summary of the invention

The objective of the invention is to realize by following technical solution: the present invention includes the light source module of radiation continuous spectrum, the colour filter module that is used for eliminate stray light and second-order diffraction spectrum, the continuously adjustable miniature monochromator of wavelength, the calibration cell module, the photoelectricity receiver module, it is characterized in that described light source module penetrates complex light, through described colour filter module, filter incoherent spectrum, focus on the seam of going into of described miniature monochromator, penetrate needed monochromatic light from the seam that goes out of described miniature monochromator, monochromatic light carries out colorimetric through described calibration cell module, is received by described photoelectricity receiver module at last.

Miniature monochromator of the present invention is realized the beam split of light path system, in the described miniature monochromator light channel structure, adopt the Fastie-Ebert light channel structure, described Fastie-Ebert light channel structure need contain a plane reflection grating and the spherical reflector that physical dimension is relatively large.Described miniature monochromator contains spherical reflector, reflection grating, two plate plane catoptrons and one group of precision drive mechanism that drives the reflection grating rotation, and wherein the effect of two described plane mirrors is to change radiation direction, optimizes described light channel structure layout.In the precision drive mechanism of described miniature monochromator, adopt stepper motor, accurate screw mandrel, special slide block, special sinusoidal arm, extension spring and grating turntable are realized the corner of described stepper motor and the proportional relation of required monochromatic wavelength.In described miniature monochromator, adopt two optocoupler initial point detection modes, survey the origin position of grating turntable and outside stepper motor, improve the wavelength accuracy and the repeatability of miniature monochromator.In miniature monochromator inside, assemble the origin position that sensor is surveyed the grating turntable, rather than feed screw nut's origin position, carry out the origin position of the described precision drive of coarse detection mechanism.And then at sensor of the outside increase of miniature monochromator,, accurately survey the origin position of gear train by surveying the corner of stepper motor.Cooperate detection by the inside and outside sensor, the wavelength that improves miniature monochromator is accurate.Because miniature monochromator is closed, internal sensor is not subject to extraneous man's activity and the occurrence positions skew, thereby causes wavelength offset.Internal sensor itself has certain accuracy in addition, therefore only needs to cooperate special software control, and the position that can debug external sensor by internal sensor promptly makes things convenient for the debugging of external sensor.Therefore miniature monochromator of the present invention compared with prior art has characteristics such as precision height, good reliability, maintainability are good.

Slide block of the present invention has the feature in a φ 6.0mm hole; Described sinusoidal arm is the screw thread thick stick that a front end has φ 6.0mm spheroidite feature.Require described φ 6.0mm hole and described φ 6.0mm spheroidite clearance fit, tolerance clearance is not more than 0.1mm.Described sinusoidal arm screws in the grating turntable, can screw in the degree of depth of described grating turntable by described sinusoidal arm, regulates the wavelength accuracy of described miniature monochromator.The rotation of described grating turntable can be finished by standard steel ball or bearing.

The present invention contains the light source and the chopper of Light-source micro-regulation physical construction, condenser lens, a radiation continuous spectrum in described light source module.Described Light-source micro-regulation physical construction can be used for finely tuning the position of described light source in light path, guarantees that the energy maximum possible that gives off of described light source focuses on the seam of going into of described miniature monochromator by described condenser lens.

Colour filter module of the present invention need comprise filter glass selection mechanism and coloured glass.Described filter glass selection mechanism contains electromagnet and is used to assemble the stand of coloured glass, by controlling the Push And Release two states of described electromagnet, correct coloured glass is placed among the light path, with the influence of elimination veiling glare or second-order diffraction spectrum.In the described coloured glass, select ultraviolet to see through visible absorbance glass, three kinds of coloured glasss such as cyanic colours glass and golden yellow glass are used to eliminate luminous energy between the influence of veiling glare, second-order diffraction light and the wavelength in the balance SPECTRAL REGION.

Calibration cell module of the present invention is used to assemble the sample cuvette and keeps the sample steady temperature.Cuvette can comprise flow colorimetric pond and cuvette.In the described calibration cell module, adopt two φ 3.0mm small balls, when the described cuvette of plug, play damping, it is loosening to occur described cuvette in the time of can preventing to test.

The present invention compared with prior art has and adopts modularization and kit form to design a whole set of light path system, and promptly a whole set of light path system is divided into several modules, adopts the kit form design in module, advantage such as make things convenient for the commissioning staff to assemble and to debug.

Brief Description Of Drawings

Fig. 1 is light path system figure of the present invention, is divided into 5 modules among the figure

Fig. 2 is light source module figure of the present invention,

Fig. 3 is a colour filter module map of the present invention

Fig. 4 is a miniature monochromator explosive view of the present invention

Fig. 5 is a miniature monochromator schematic internal view of the present invention

Fig. 6 is a miniature monochromator optical schematic diagram of the present invention

Fig. 7 is a screw component synoptic diagram of the present invention

Fig. 8 is a grating turntable assembly synoptic diagram of the present invention

Fig. 9 is miniature monochromator of the present invention and peripheral component assembling relationship figure

Figure 10 is a calibration cell module map of the present invention

Figure 11 is a calibration cell of the present invention

Embodiment

Describe the present invention in detail below in conjunction with pattern.

The present invention is a kind of novelty, has adopted miniature monochromator to realize the clinical inspection analytic instrument light path system of beam split.It comprises light source module 1, colour filter module 2, miniature monochromator 3, calibration cell module 4 and receiver module 5.As shown in Figure 1, light source module 1 penetrates a branch of complex light, this complex light is modulated into the light beam of regular fast continuous break-make through the chopper of 1 li of light source module, this light beam is through colour filter module 2, filter incoherent spectrum, become the narrower complex light of a branch of spectral range, focus on the seam of going into of miniature monochromator 3 at last.The beam splitting system structure of miniature monochromator 3 has adopted the Fastie-Ebert light channel structure.Enter the complex light of monochromator, through beam splitting system, the seam that goes out from miniature monochromator 3 penetrates needed monochromatic light at last.Monochromatic light carries out colorimetric through calibration cell module 4, is received by photoelectricity receiver module 5 at last.Below with the composition and the function of each module of more detailed description.

As shown in Figure 2, light source module 1 comprises bulb 6, direct current micromotor 7, chopper 8, condenser 9, light source base 10, compression spring 11, lamp socket setting nut 12 and light source fixed head 13.Bulb 6 to around the radiation continuous spectrum.Part continuous spectrum is focused into a branch of converging beam through condenser 9.Chopper is positioned at the condenser back, will restraint converging beam to this and modulate, and is modulated into the light beam of a branch of continuously quick break-make.What this light beams finally converged to miniature monochromator 3 goes into the seam place.In Fig. 2, the guide rail on the light source base 10, can guarantee light source base 10 on light source fixed head 13 among a small circle horizontal direction move freely.Position by compression spring 11 and lamp socket setting nut 12 fine setting light source bases can allow the filament of bulb 6 be positioned at the optical axis of condenser 9, thereby allow luminous energy as much as possible enter miniature monochromator 3.

Because the grating beam splitting oneself factor for example exists influence of second-order diffraction spectrum and bias light degree to be difficult to reach 10 ^-6, therefore increased colour filter module 2, one in the present invention, eliminate the influence of visible light under near ultraviolet band, the 2nd, eliminate the influence of second-order diffraction spectrum, the 3rd, the luminous energy between the balance monochromatic wavelength to a certain extent.In Fig. 3, the colour filter module has comprised electromagnet 14, and ultraviolet sees through visible absorbance glass 15, filter glass seat 16,16 li of golden yellow glass 17 and cyanic colours glass 18. golden yellow glass 17 and cyanic colours glass 18 stack assembling filter glass seats.By to the control of electromagnet 14 break-makes, can freely select ultraviolet to see through visible absorbance glass 15 or golden yellow glass 17 and cyanic colours glass 18 and place among the light path.Filter glass seat 16 is close to miniature monochromator 3.

Miniature monochromator is pocket-size, as to have a precision drive mechanism optical instrument as core component of the present invention.For convenience of description, we are divided into miniature monochromator 3: screw component 19, and left plate assembly 20, grating turntable assembly 21 and right plate assembly 22 are shown in the explosive view of the miniature monochromator of Fig. 4.Shown in the schematic internal view of the miniature monochromator of Fig. 5,, will drive slide block 24 and move horizontally when rotary screw 23.Because the spheric end of sinusoidal arm 25 and the φ 6.0mm hole contact matching of slide block 24, the spheric end that will drive sinusoidal arm 25 that moves horizontally of slide block 24 slides at φ 6.0mm inside groove, thereby promote 21 rotations of grating turntable assembly, realize the sinusoidal variations of slide block displacement and grating rotating angle.According to grating equation,

$2\sin \left(\frac{\mathrm{\α}+\mathrm{\β}}{2}\right)\cos \left(\frac{\mathrm{Dv}}{2}\right)={10}^{16}*\mathrm{Kn\λ}$

Monochromatic wavelength X becomes sine relation with grating rotating angle (alpha+beta), and therefore by stepper motor 44 control screw mandrels, and the rotation of drive grating turntable just can obtain needed target wavelength.Based on grating equation, the present invention has adopted the Fastie-Ebert light channel structure, as shown in Figure 6.Complex light from light source module 1 focuses on into seam 26, and through plane mirror 27 reflection, be mapped to spherical reflector spherical reflector 28. this moment 28 incident beam is changed direct of travel, and collimation directive plane reflection grating 29.By 23 rotations of control screw mandrel, allow plane reflection grating 29 be in special angle (alpha+beta), then diffraction goes out specific monochromatic wavelength on the β direction.Half part in addition of specific monochromatic wavelength normal sheaf spherical reflector 28 is passed through plane mirror 27 again, finally penetrates miniature monochromator 3 from going out seam 30.

Next the above-mentioned principle of work of introducing miniature monochromator 3 roughly will introduce the implementation of miniature monochromator 3 in detail, promptly drive the precision drive mechanism of plane reflection grating 29 rotations.It is a spotlight of the present invention.In precision drive of the present invention mechanism, adopt accurate screw mandrel, special slide block, special sinusoidal arm and grating turntable, drive 29 rotations of plane reflection grating.As shown in Figure 7, the synoptic diagram of screw component 19.Special slide block 24 is special structures, bores the hole of a φ 6.0mm, is used for cooperating with sinusoidal arm 25.Slide block 24 lock onto on the nut of screw mandrel 23, and right limit device 31 and left limit device 32 have played the nut moving range of restriction screw mandrel 23, prevent to destroy grating turntable assembly 21.Screw component 19 is assemblied in left plate assembly 20 and right plate assembly 22.By the position of minor adjustments screw mandrel adjustment seat 39, can keep the concentricity of screw component 19, also make things convenient for the dismounting of screw component 19 simultaneously.

Synoptic diagram as Fig. 8 grating turntable assembly 21.Grating turntable 34 assemble less bearing 37 up and down respectively and larger axis holds 33; Plane reflection grating 29 is pasted on grating turntable 34; Sinusoidal arm 25 screws in grating turntable 34; In the middle of two set nuts 36 spring base is arranged.Sinusoidal arm 25 1 ends are spherical, and this spheroid cooperates with slide block 24.The φ 6.0mm spheroid of sinusoidal arm 25 cooperates with the hole of the φ 6.0mm of slide block 24, and tolerance clearance is less than 0.1mm.Hold sinusoidal arm 25 other ends by extension spring 46, allow the spheroid of sinusoidal arm 25 be close to the hole inwall of slide block 24, when screw mandrel rotates round about, the spheroid of sinusoidal arm 25 is close to the inner arm of slide block 24 all the time, does not influence wavelength accuracy thereby produce back to the gap.

On the grating turntable, assemble a fanning strip 35 in addition, be used for the reference position of mark grating turntable, i.e. the origin position of precision drive mechanism.The position transducer 40 that is assemblied in 22 li of right plate assemblies is surveyed the position of fanning strip 35, i.e. origin position.Because the dispersion angle of plane reflection grating 29 is about 0.07 °/nm, it is 14.3nm/1 °, therefore if satisfy ± the 2nm wavelength accuracy, then the angle precision of position transducer 40 detection fanning strips 35 needs in ± 0.14 °, but to common sensor, be photoelectrical coupler, be difficult to realize this precision.In order to improve the detection accuracy of origin position, settle a sensor again in the monochromator outside.As shown in Figure 9, on shaft coupling 43, assemble a synchronizing wheel 42, open the logical light groove of a wide 1mm on the disk of synchronizing wheel 42.Angle of assembling sensor 41 on the side plate 45 of fixing stepper motor 44 simultaneously is by the logical light groove of angular transducer 41 detection synchronizing wheels 42.The logical light groove 1mm width of synchronizing wheel 42, the running accuracy of corresponding screw mandrel 23 ± 3 °.Because screw mandrel 23 rotates a circle, the about 46nm of wavelength that miniature monochromator 3 produces produces 0.128nm for 1 ° through 42 rotations of conversion synchronizing wheel.Therefore survey by angular transducer 41, can reach ± detection accuracy of 0.4nm.This precision is finished and is satisfied the requirement of clinical examination instrument, and promptly wavelength accuracy ± 2nm is repeated less than 1.5nm.In a word, the interior location sensor 40 coarse detection origin positions of miniature monochromator 3, trueness error is controlled at ± 4nm in, and then accurately survey by miniature monochromator 3 exterior angle sensors 41, trueness error is narrowed down to ± 0.4nm from ± 4nm.

Figure 10 is the wiring layout of calibration cell module 4, comprises fan 47, heating radiator 48, Pa Er card 49, calibration cell 50, calibration cell lid cotton 51, heat-preservation cotton 52 and temperature sensor 53.Pa Er card 49 is assemblied between calibration cell 50 and the heating radiator 48.Control by Pa Er card 49 and temperature sensor 53 heats calibration cell 50 or the constant stable control of freezing.47 in heating radiator 48 and fan are that unnecessary heat is shed.In calibration cell 50 mounted inside two φ 3.0mm balls 55 are arranged, play damping.The hole of passing through of the right and left of calibration cell 50 is a conical in shape, clear aperature φ 2.5mm.

At receiver module mount pad 54 of calibration cell module assembling, be used to assemble receiver module 5 in addition.

The photoelectric receiving device that receiver module is 5 li adopts ultraviolet enhancement silicon photo diode, spectral response range 190～900nm.

Claims (17)

1, a kind of light path system of clinical inspection analytic instrument, the light source module that includes the radiation continuous spectrum, the colour filter module that is used for eliminate stray light and second-order diffraction spectrum, the continuously adjustable miniature monochromator of wavelength, the calibration cell module, the photoelectricity receiver module, it is characterized in that described light source module penetrates complex light, through described colour filter module, filter incoherent spectrum, focus on the seam of going into of described miniature monochromator, penetrate needed monochromatic light from the seam that goes out of described miniature monochromator, monochromatic light carries out colorimetric through described calibration cell module, is received by described photoelectricity receiver module at last.

2, the light path system of clinical inspection analytic instrument according to claim 1, it is characterized in that the beam split of described miniature monochromator realization light path system, in the described miniature monochromator light channel structure, adopt the Fastie-Ebert light channel structure, described Fastie-Ebert light channel structure need contain a plane reflection grating and the spherical reflector that physical dimension is relatively large.

3, the light path system of clinical inspection analytic instrument according to claim 2 is characterized in that in described miniature monochromator structure, by adopting two described plane mirrors, changes radiation direction, optimizes described light channel structure layout.

4, the light path system of clinical inspection analytic instrument according to claim 3 is characterized in that described miniature monochromator contains spherical reflector, reflection grating and one group of precision drive mechanism that drives the reflection grating rotation.

5, the light path system of clinical inspection analytic instrument according to claim 4, it is characterized in that in the precision drive mechanism of described miniature monochromator, adopt stepper motor, accurate screw mandrel, special slide block, special sinusoidal arm, extension spring and grating turntable are realized the corner of described stepper motor and the proportional relation of required monochromatic wavelength.

6, the light path system of clinical inspection analytic instrument according to claim 5 is characterized in that in the precision drive mechanism of described miniature monochromator, assembles a position transducer, is used for the origin position of the described precision drive of coarse detection mechanism.

7, the light path system of clinical inspection analytic instrument according to claim 5 is characterized in that angular transducer of the outside increase of described miniature monochromator, is used for the accurately origin position of the described precision drive of detection mechanism.

8, the light path system of clinical inspection analytic instrument according to claim 5 is characterized in that described slide block has the feature in a φ 6.0mm hole; Described sinusoidal arm is the screw thread thick stick that a front end has φ 6.0mm spheroidite feature.Require described φ 6.0mm hole and described φ 6.0mm spheroidite clearance fit, tolerance clearance is not more than 0.1mm.

9, according to the light path system of claim 5 or 8 described clinical inspection analytic instruments, it is characterized in that described sinusoidal arm screws in the grating turntable, can screw in the degree of depth of described grating turntable by described sinusoidal arm, regulate the wavelength accuracy of described miniature monochromator.

10, the light path system of clinical inspection analytic instrument according to claim 5 is characterized in that the rotation of described grating turntable can be finished by standard steel ball or bearing.

11, the light path system of clinical inspection analytic instrument according to claim 1 is characterized in that in described light source module, contain Light-source micro-regulation physical construction, condenser lens,

The light source of a radiation continuous spectrum and chopper.

12, the light path system of clinical inspection analytic instrument according to claim 11, it is characterized in that described Light-source micro-regulation physical construction can be used for finely tuning the position of described light source in light path, guarantee that the energy maximum possible that gives off of described light source focuses on the seam of going into of described miniature monochromator by described condenser lens.

13, the light path system of clinical inspection analytic instrument according to claim 1 is characterized in that described colour filter module need comprise filter glass selection mechanism and coloured glass.

14, the light path system of clinical inspection analytic instrument according to claim 13, it is characterized in that described filter glass selection mechanism contains electromagnet and the stand that is used to assemble coloured glass, by controlling the Push And Release two states of described electromagnet, correct coloured glass is placed among the light path, to eliminate the influence of veiling glare or second-order diffraction spectrum.

15, the light path system of clinical inspection analytic instrument according to claim 14, it is characterized in that in the described coloured glass, select ultraviolet to see through visible absorbance glass, three kinds of coloured glasss such as cyanic colours glass and golden yellow glass are used to eliminate luminous energy between the influence of veiling glare, second-order diffraction light and the wavelength in the balance SPECTRAL REGION.

16, the light path system of clinical inspection analytic instrument according to claim 1 is characterized in that described calibration cell module is used to assemble the sample cuvette and keeps the sample steady temperature.Cuvette can comprise flow colorimetric pond and cuvette.

17, the light path system of clinical inspection analytic instrument according to claim 16, it is characterized in that in the described calibration cell module, adopt two φ 3.0mm small balls, when the described cuvette of plug, play damping, it is loosening to occur described cuvette in the time of can preventing to test.

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