CN210005428U - Optical detection module of biochemical and specific protein analyzer based on double-lens structure of Rowland grating - Google Patents

Optical detection module of biochemical and specific protein analyzer based on double-lens structure of Rowland grating Download PDF

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Publication number
CN210005428U
CN210005428U CN201920676055.2U CN201920676055U CN210005428U CN 210005428 U CN210005428 U CN 210005428U CN 201920676055 U CN201920676055 U CN 201920676055U CN 210005428 U CN210005428 U CN 210005428U
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China
Prior art keywords
lens
rowland grating
cuvette
center
light
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CN201920676055.2U
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Chinese (zh)
Inventor
倪屹
李俊纬
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Wuxi Hengli Medical Technology Co Ltd
Shanghai Zhen Yuan Diagnostic Article Science And Technology Ltd
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Wuxi Hengli Medical Technology Co Ltd
Shanghai Zhen Yuan Diagnostic Article Science And Technology Ltd
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Abstract

The utility model provides an biochemical and specific protein analyzer's light detection module based on rowland grating's double-lens structure, including light source, focusing lens, cell front surface, cell rear surface, convergent lens, slit structure, rowland grating, front lens, rear lens, photoelectric detector, light source, focusing lens, cell front surface, cell rear surface, convergent lens, slit structure, rowland grating all pass same central line in proper order along the light path that the light source sent light backward in the past, light source center, focusing lens center, cell front surface center, cell rear surface center, convergent lens center, slit structure center and rowland grating center, front lens, rear lens, photoelectric detector set up the side below in rowland grating the place ahead, set gradually along the light path of rowland grating diffraction back light the utility model discloses wavelength resolution is high, spectral range , simple structure.

Description

Optical detection module of biochemical and specific protein analyzer based on double-lens structure of Rowland grating
Technical Field
The utility model relates to a concave surface grating spectral imaging system that is used for specific protein analysis appearance and biochemical analysis appearance optical detection, especially usable double lens structure that use rowland grating as the basement realize the planar optical detection module of spectrum.
Background
Biochemical analyzers (Biochemical analyzers) and Specific protein analyzers (Specific protein analyzers) detect antigen-antibody reactions by spectroscopic methods and spectroscopic methods, and reflect Biochemical indicators of Specific proteins, enzymes, and metabolites In serum, plasma, and urine by photoelectric signals to assist doctors In Vitro Diagnosis (IVD). The concentration of various items such as glutamic-pyruvic transaminase (ALT), C-reactive protein (CRP), serum Total Protein (TP), urea nitrogen (BUN), Creatinine (CRE) and the like can be detected, and the detection result is compared with a reference value to judge whether human body tissues are diseased or not.
The existing instruments mostly adopt a concave grating represented by a flat-field concave grating or a Roland grating as a light splitting device. The concave grating has the functions of dispersion and diffraction, can decompose the complex color light into continuous spectrums, and the photoelectric device can convert the spectrum intensity into an electric signal to reflect the concentration of a sample.
The imaging spectrum of the Rowland grating is a spherical structure and is not easy to detect; the diffraction constraint conditions of the flat-field concave grating are complicated, and a nonlinear equation set of different aberration items needs to be solved so as to eliminate specific aberration and compensate an image plane, and the process is complex; the commonly used Czerny-Turner type concave grating has a complex structure, is not easy to miniaturize and has obvious attenuation of light intensity and flux.
Disclosure of Invention
The utility model aims at overcoming the not enough that exists among the prior art, provide kinds of biochemical and specific protein analyzer's light detection module based on the double-lens structure of rowland grating to rowland grating is the basement, and the sphere spectrum diffraction that application double-lens structure can present originally with rowland grating assembles the flat field, and wavelength resolution is high, spectral range , simple structure, convenient reading, easily application, the utility model discloses a technical scheme be:
A light detection module of biochemical and specific protein analyzer based on Loran grating double-lens structure, comprising:
the device comprises a light source, a focusing lens, a cuvette front surface, a cuvette rear surface, a converging lens, a slit structure, a Rowland grating, a front lens, a rear lens and a photoelectric detector;
the light source, the focusing lens, the front surface of the cuvette, the rear surface of the cuvette, the converging lens, the slit structure and the Rowland grating are sequentially arranged from front to back along a light path of light emitted by the light source;
the light source center, the focusing lens center, the cuvette front surface center, the cuvette rear surface center, the converging lens center, the slit structure center and the Rowland grating center sequentially penetrate through the same center line;
the front lens, the rear lens and the photoelectric detector are arranged below the side in front of the Rowland grating and are sequentially arranged along the light path of light rays diffracted by the Rowland grating.
, the light source is embedded in ellipsoidal reflector planes, and the ellipsoidal reflector planes are used for converging the light emitted by the light source.
Further , the focus lens is mounted on a focus lens mount that is mounted on the focus lens pitch rail.
, respectively arranging the front surface and the rear surface of the cuvette on the front and rear surfaces of the cuvette, arranging the cuvette in the cuvette seat, arranging the cuvette seat on the adjustment guide rail of the cuvette seat, and respectively arranging a front light through hole groove and a rear light through hole groove on the front side and the rear side of the cuvette seat.
the converging lens is installed at the front end of the screw distance adjusting structure, the screw distance adjusting structure is hollow for light to pass through, and the slit structure is arranged at the rear side of the screw distance adjusting structure.
, the width of the slot structure is adjustable.
, the front lens and the rear lens are both convex lenses, and they form an angle of degrees, such as an angle of 10-15 degrees.
, the slit structure, the rowland grating, the front lens, the back lens, and the photodetector are all fixed in a closed housing.
, the Rowland grating is mounted on a Rowland grating rotary circular table.
The utility model has the advantages that the utility model discloses with the spheroidisation continuous spectrum transition that rowland grating originally presented to the plane field, made things convenient for photoelectric detector's direct reading, spectral resolution reaches the highest 0.5nm that can reach, and overall resolution is superior to 1.7nm the utility model discloses simple structure, light path are succinct, spectral range , convenient regulation, can miniaturation, practicality are strong.
Drawings
Fig. 1 is a schematic diagram of the overall light path of the present invention.
Fig. 2 is an overall mechanical diagram of the present invention.
Fig. 3 is an overall mechanical diagram of the present invention including the housing.
Detailed Description
The present invention will now be described with reference to the following specific figures and examples, at .
The utility model provides an kinds of biochemical and specific protein analyzer's optical detection module (optical detection module for short hereafter) based on rowland grating's two lens structure, as shown in figure 1, include:
the device comprises a light source 1, a focusing lens 2, a cuvette front surface 3, a cuvette rear surface 4, a converging lens 5, a slit structure 6, a Rowland grating 7, a front lens 8, a rear lens 9 and a photoelectric detector 10;
the light source 1, the focusing lens 2, the cuvette front surface 3, the cuvette rear surface 4, the converging lens 5, the slit structure 6 and the Rowland grating 7 are sequentially arranged from front to back along a light path of light emitted by the light source;
the center of the light source 1, the center of the focusing lens 2, the center of the front surface 3 of the cuvette, the center of the rear surface 4 of the cuvette, the center of the converging lens 5, the center of the slit structure 6 and the center of the Rowland grating 7 sequentially penetrate through the same center line;
the front lens 8, the rear lens 9 and the photoelectric detector 10 are arranged below the front side of the Rowland grating 7 and are sequentially arranged along the light path of the light diffracted by the Rowland grating 7.
As shown in figures 2 and 3 of the drawings,
the light source 1 can be embedded in light source ellipsoid reflecting mirror surfaces 11, and the light source ellipsoid reflecting mirror surfaces 11 can converge the light emitted by the light source 1, so that the energy loss of the light emitted to the focusing lens 2 is reduced;
the focusing lens 2 is arranged on a focusing lens fixing support 21, and the focusing lens fixing support 21 is arranged on a focusing lens distance-adjusting guide rail 22; the focusing lens 2 can adjust the position in the front-back direction and can be used for adjusting the focusing light;
the front surface 3 and the rear surface 4 of the cuvette are respectively positioned on the front surface and the rear surface of the cuvette 3a, the cuvette 3a is arranged in the cuvette seat 31, and the cuvette seat 31 is arranged on the cuvette seat adjusting guide rail 32 to realize the front-rear position adjustment of the cuvette 3 a; the front side and the rear side of the cuvette seat 31 are respectively provided with a front light through hole groove 33 and a rear light through hole groove 34;
the converging lens 5 is arranged at the front end of the threaded distance adjusting structure 51, and light rays pass through the hollow part of the threaded distance adjusting structure 51; the converging lens 5 is mounted on the threaded distance adjustment structure 51 in order to adjust the position of the converging point;
the slit structure 6 is arranged at the rear side of the thread distance adjusting structure 51, the width of the slit structure 6 is adjustable, and the slit structure is used for adjusting the width of light irradiating on the Rowland grating, so that the imaging effect is adjusted;
the focusing lens distance-adjusting guide rail 22, the cuvette seat distance-adjusting guide rail 32 and the thread distance-adjusting structure 51 are respectively used for adjusting the front and back positions of the focusing lens 2, the cuvette seat 31 and the convergent lens 5, so that the spectrum imaging effect is adjusted;
the front lens 8 and the rear lens 9 are both convex lenses, for example, can be in the forms of double convex, plano-convex, concave-convex and the like, form an angle of degrees, for example, 10-15 degrees, and convert the original continuous spherical spectrum diffracted by the Rowland grating into a plane;
the slit structure 6, the Rowland grating 7, the front lens 8, the rear lens 9 and the photoelectric detector 10 are all fixed in the closed shell;
the Rowland grating 7 is arranged on the Rowland grating rotating round table 71, and the Rowland grating rotating round table 71 can rotate clockwise or anticlockwise to control the position and the effect of an imaging spectrum;
the light source 1 emits light rays, and the light source ellipsoid reflecting mirror surface 11 can converge the light rays of the light source 1 into light beams with smaller diameters and pass through the focusing lens 2; then, the light beam can enter the front surface 3 of the cuvette through the front light through hole groove 33 of the cuvette seat 31 and then pass through the inside of the cuvette 3a, the liquid or air in the cuvette has color or turbidity, the light beam is attenuated when passing through the inside of the cuvette 3a, and the attenuated light is emitted out of the rear light through hole groove 34 of the cuvette seat through the rear surface 4 of the cuvette; the light beam passes through the converging lens 5, passes through the thread distance adjusting structure 51, reaches the slit structure 6, continues to irradiate the Rowland grating 7, the light diffracted by the Rowland grating 7 passes through the front lens 8 and the refraction of the rear lens 9, and the originally presented spherical spectrum is transited to the plane field spectrum and is read by the photoelectric detector 10;
the photoelectric detector 10 is a non-equidistant photodiode, and can directly read monochromatic light with fixed wavelength of the spectral band; filters of fixed wavelength may be added to the surface of the photodetector 10 to improve accuracy.
Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting, and although the present invention has been described in detail with reference to the examples, those skilled in the art should understand that the technical solutions of the present invention can be modified or replaced by equivalents without departing from the spirit and scope of the technical solutions of the present invention, which should be covered by the scope of the claims of the present invention.

Claims (10)

1, optical detection module of biochemical and specific protein analyzer based on Rowland grating double-lens structure, which is characterized in that it comprises:
the device comprises a light source (1), a focusing lens (2), a cuvette front surface (3), a cuvette rear surface (4), a converging lens (5), a slit structure (6), a Rowland grating (7), a front lens (8), a rear lens (9) and a photoelectric detector (10);
the light source (1), the focusing lens (2), the cuvette front surface (3), the cuvette rear surface (4), the converging lens (5), the slit structure (6) and the Rowland grating (7) are sequentially arranged from front to back along a light path of light emitted by the light source;
the center of the light source (1), the center of the focusing lens (2), the center of the front surface (3) of the cuvette, the center of the rear surface (4) of the cuvette, the center of the converging lens (5), the center of the slit structure (6) and the center of the Rowland grating (7) sequentially penetrate through the same center line;
the front lens (8), the rear lens (9) and the photoelectric detector (10) are arranged below the front side of the Rowland grating (7) and are sequentially arranged along the light path of the light after diffraction of the Rowland grating (7).
2. The optical detection module of the biochemical and specific protein analyzer based on the Rowland grating dual-lens structure as claimed in claim 1,
the light source (1) is nested in light source ellipsoid reflecting mirror surfaces (11), and the light source ellipsoid reflecting mirror surfaces (11) are used for converging light rays emitted by the light source (1).
3. The optical detection module of the biochemical and specific protein analyzer based on the Rowland grating dual-lens structure as claimed in claim 1,
the focusing lens (2) is arranged on a focusing lens fixing support (21), and the focusing lens fixing support (21) is arranged on a focusing lens distance adjusting guide rail (22).
4. The optical detection module of the biochemical and specific protein analyzer based on the Rowland grating dual-lens structure as claimed in claim 1,
the front surface (3) and the rear surface (4) of the cuvette are respectively positioned on the front surface and the rear surface of the cuvette (3a), the cuvette (3a) is arranged in a cuvette seat (31), and the cuvette seat (31) is arranged on a cuvette seat adjusting guide rail (32); the front side and the rear side of the cuvette seat (31) are respectively provided with a front light through hole groove (33) and a rear light through hole groove (34).
5. The optical detection module of the biochemical and specific protein analyzer based on the Rowland grating dual-lens structure as claimed in claim 1,
the converging lens (5) is arranged at the front end of the threaded distance adjusting structure (51), and light rays pass through the threaded distance adjusting structure (51) in a hollow mode; the slit structure (6) is arranged at the rear side of the thread distance adjusting structure (51).
6. The optical detection module of the biochemical and specific protein analyzer based on the Rowland grating dual-lens structure as claimed in claim 1,
the width of the slit structure (6) is adjustable.
7. The optical detection module of the biochemical and specific protein analyzer based on the Rowland grating dual-lens structure as claimed in claim 1,
the front lens (8) and the rear lens (9) are both convex lenses.
8. The optical detection module of the biochemical and specific protein analyzer based on the Rowland grating dual-lens structure as claimed in claim 1,
the slit structure (6), the Rowland grating (7), the front lens (8), the rear lens (9) and the photoelectric detector (10) are all fixed in the closed shell.
9. The optical detection module of the biochemical and specific protein analyzer based on the Rowland grating dual-lens structure as claimed in claim 1,
the Rowland grating (7) is arranged on the Rowland grating rotating round table (71).
10. The optical detection module of the biochemical and specific protein analyzer based on the Rowland grating dual-lens structure as claimed in claim 1,
the front lens (8) and the rear lens (9) form an angle of 10-15 degrees.
CN201920676055.2U 2019-05-13 2019-05-13 Optical detection module of biochemical and specific protein analyzer based on double-lens structure of Rowland grating Expired - Fee Related CN210005428U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201920676055.2U CN210005428U (en) 2019-05-13 2019-05-13 Optical detection module of biochemical and specific protein analyzer based on double-lens structure of Rowland grating

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201920676055.2U CN210005428U (en) 2019-05-13 2019-05-13 Optical detection module of biochemical and specific protein analyzer based on double-lens structure of Rowland grating

Publications (1)

Publication Number Publication Date
CN210005428U true CN210005428U (en) 2020-01-31

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Country Status (1)

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Granted publication date: 20200131