CN101007997A - Axial center aeration and jet-booster type stirring fermenter - Google Patents

Axial center aeration and jet-booster type stirring fermenter Download PDF

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Publication number
CN101007997A
CN101007997A CN 200710000013 CN200710000013A CN101007997A CN 101007997 A CN101007997 A CN 101007997A CN 200710000013 CN200710000013 CN 200710000013 CN 200710000013 A CN200710000013 A CN 200710000013A CN 101007997 A CN101007997 A CN 101007997A
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China
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air
stirring
booster type
jet
axle
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CN 200710000013
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Chinese (zh)
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王书堂
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02Stirrer or mobile mixing elements
    • C12M27/04Stirrer or mobile mixing elements with introduction of gas through the stirrer or mixing element

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention is to ventilate compressed air into fermentation tank through stirring axial core, and open cell on blade or ventilate air to short pipe cooperated with position and way of paddle, the air outlet is near to paddle to reach maximum diintegration degree, and mix instantly with liquid. The invention overcomes the shortcomings of relative long route of air in other ventilating way, direct rising of bubble to liquid upper side without passing through stirring area, and low avalability rate of air (oxygen), and reduces energy consumption, such as time, stirring power and ventilating amount. The counteracting force of air injector boosts the sitirring and favourable for increasing stirring efficiency and saving energy.

Description

A kind of axial center aeration and jet-booster type stirring fermenter
Technical field
Fermentation equipment in chemical industry, medicine, biology, food, the light industry.
Background technology
21st century is the century based on biotechnology, and fermentation is the basis of biotechnology industry.The biological respinse macrokinetics is the basis of optimizing fermentation, and bio-reactor is the outside atmosphere of fermenting process, and it influences the efficient and the optimization of fermenting process equally.
The aeration-agitation fermentation equipment is used widely in the fermentation equipment, but ventilating mode in any case, and air is all served as reasons and outside ventilated by sparger etc. through pipeline access arrangement inside separately.The present invention is fully smashed gas by changing ventilating mode exactly, makes the gas-liquid thorough mixing, reaches to improve dissolved oxygen rate, reduction energy consumption, thereby improves the equipment of fermentative production level.
Summary of the invention
The present invention is that the stir shaft core that pressurized air passes through fermentor tank feeds device interior, cooperates the position and the form of stirring arm, rationally axle radially or perforate on the stirring blade (or short tube) import air.We can obtain to draw a conclusion thus: because the relative position of pneumatic outlet and stirring arm is very near, make air obtain farthest smashing, and fully quick and liquid mixing.Overcome other ventilating modes (gas is through long relatively path, and part is not passed through stirring area) bubble and directly be raised to liquid level upper end, the low shortcoming of oxygen (air) utilization ratio.Thereby fermenting process be optimized and improved efficient, reached following effect:
1, since air smash and fully improved dissolved oxygen rate, thereby improved the fermentative production level, promptly improve production concentration (fermentation unit), substrate conversion efficiency and production intensity (fermentation period).
2, from last advantage as can be known when the identical production level, but save energy, reduce production costs.
3, nozzle placement is in the relative sense of rotation of the paddle back lower place, and promptly jet direction is opposite with the stirring sense of rotation.Air has played the effect that boosting stirs like this, thereby can reduce power of agitator relatively, reaches the purpose of save energy.
4, because the agitator centrifugation makes the nozzle place produce negative pressure, help the save compressed air power source like this.
Description of drawings
Figure is the bioreactor construction synoptic diagram.
Embodiment
Fermentor tank adopts universal machine stirred fermentor tank structure, only is described stirring blow and vent system.
This equipment adopts the setting product of motor 1 side and speed reduction unit 2 direct connection forms, the speed reduction unit design selection be about two ends through type output shaft form.Speed reduction unit 2 is installed on the upper end of fermentor tank tank body 4 by support 3.
Stir shaft 5 is selected thick-wall seamless for use, through precision sizing (assurance concentricity).Generally two portions be should make, semiaxis and following semiaxis (reactor of compact can be made an axle) promptly gone up.The fixed support method and the common response device of axle are basic identical.Difference just is that the upper end extension of axle is equipped with inversion mechanical seal 6, so that pressurized air imports.I.e. upper end inversion mechanical seal links to each other with speed reduction unit through support 7, and rotating ring is installed.Stationary ring is connected with outside air ingress pipe 8, and mechanical sealing linkage ring matches with stir shaft.This mechanism design has been finished under rotary state and through hollow stir shaft (being equal to air lead) pressurized air has been imported fermentor tank.
After pressurized air imports hollow stir shaft, be ejected into (agitator need not adopt the form of center tep reel, and bubble can not be raised to liquid level along the stir shaft short circuit) in the bio-reactor via hollow stirring blade 9.The same employing of paddle is hollow makes through punching press or welding, can be according to kind design paddle form and definite paddle quantity of different fermentations product.At paddle lower edge non-uniform Distribution perforate welding tip 10, nozzle is to oblique arranged beneath and opposite with the stirring sense of rotation.The relative nozzle bore of far-end strengthens, and promptly strengthens air flow quantity.Can guarantee as far as possible that like this air is evenly distributed in liquid.Air is derived the back and can fully be disperseed under action of centrifugal force in addition, and is fully smashed through very short distance under the effect of next paddle and mixed, has avoided bubble to take place without smashing the situation that rises to liquid level.Improved the utilization ratio of air greatly, dissolved oxygen rate improves in the liquid thereby make.Simultaneously the reactive force of air nozzle plays the effect of boosting to stirring, helps the raising of stirring efficiency, the saving of the energy.The centrifugal force that agitator produces makes the nozzle place produce negative pressure, helps the saving in compressed-air power source.
Other block construction of this equipment is selected for use according to kind, and existing forming technique is not described.
The present invention can only be described with structure sign, functional character in experiment.Because of the factor of influence in the fermentative production experiment is very many, the existing scientific and technological ability of some parameter can't all realize Comparative and Quantitative Analysis.General influence factor has: hardware condition of the control of kind, seed quality, the substratum similarities and differences, disinfecting action, each index of production process, operator's level, production or the like, multinomial dynamic factor make the data contrast be difficult for realizing.
Reference:
" production of antibiotics equipment " Yu Juntang of Chemical Industry Press chief editor
" fermentation industry pandect " Chinese Medicine science and technology Yin Guang of press beautiful jade war Garrick Zhao Gennan chief editor
" biochemical engineering " Chinese Medicine science and technology press Wang Meng building bear is defended the owner and compiles
" microbiological pharmacy " Wu Jianbo of Chemical Industry Press chief editor
" optimizing fermentation principle and put into practice " Chen Jian Li Yin of Chemical Industry Press chief editor
" biological respinse engineering " Ka Er of press of Chengdu Univ. of Science ﹠ Technology. Xu Geer (moral) chief editor
" bio-pharmaceuticals equipment and separating and purifying technology " Li Jin Yu Yong of Chemical Industry Press thunderbolt Dong Dexiang chief editor.

Claims (4)

1, a kind of core jet-booster type stirred fermentor, it comprises whipping appts, breather, tightness system, it is characterized in that: described fermentor tank is that pressurized air passes through stir shaft, imports fermentor tank through stirring arm by the outside.
2, axle core jet-booster type stirred fermentor as claimed in claim 1, it is characterized in that: the stir shaft in the whipping appts all is a tubular shaft, and the axle top links to each other with the external compression air leading-in conduit through being inverted mechanical seal.
3, axle as claimed in claim 1 core jet-booster type stirred fermentor, it is characterized in that: the stirring arm in the whipping appts is punching press or the hollow stirring arm of welding fabrication, and the importing pressurized air that communicates with the hollow stir shaft.
4, axle core jet-booster type stirred fermentor as claimed in claim 3 is characterized in that: non-homogeneous air jet of arranging is arranged on the stirring blade or spray short tube.
CN 200710000013 2007-01-04 2007-01-04 Axial center aeration and jet-booster type stirring fermenter Pending CN101007997A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 200710000013 CN101007997A (en) 2007-01-04 2007-01-04 Axial center aeration and jet-booster type stirring fermenter

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 200710000013 CN101007997A (en) 2007-01-04 2007-01-04 Axial center aeration and jet-booster type stirring fermenter

Publications (1)

Publication Number Publication Date
CN101007997A true CN101007997A (en) 2007-08-01

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Family Applications (1)

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CN 200710000013 Pending CN101007997A (en) 2007-01-04 2007-01-04 Axial center aeration and jet-booster type stirring fermenter

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CN (1) CN101007997A (en)

Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102836665A (en) * 2012-09-19 2012-12-26 常州大学 Mixing stirrer with paddle with airflow driven by air pressure
CN102895902A (en) * 2012-11-09 2013-01-30 泰山医学院 Hydraulic power driving mixing agitator
CN103834555A (en) * 2013-12-19 2014-06-04 柳州市京阳节能科技研发有限公司 Multifunctional efficient and energy-saving fermentation tank
CN104403929A (en) * 2014-12-21 2015-03-11 遵义联谷农业科技有限公司 Liquid strain fermentation tank
CN105199909A (en) * 2015-10-27 2015-12-30 高州市和友酒业有限公司 High-pressure gas stirring type fermentation tank
CN105695320A (en) * 2015-12-10 2016-06-22 柳州市京阳节能科技研发有限公司 Efficient sanitary environment-friendly fermentation device
CN105688782A (en) * 2016-01-28 2016-06-22 王海龙 Temperature control and stirring integrated device
CN106867870A (en) * 2017-04-28 2017-06-20 天津科技大学 A kind of L threonines produce tank and threonine production technology
CN107297192A (en) * 2017-07-27 2017-10-27 浙江长江搅拌设备有限公司 A kind of gas, solid, liquid reaction unit
CN107354091A (en) * 2017-08-31 2017-11-17 江苏天琦生物科技有限公司 A kind of soya-bean polypeptides enzymolysis device
CN107470039A (en) * 2017-08-01 2017-12-15 鲁南制药集团股份有限公司 A kind of Alcohol-settling tank, horizontal screw centrifuge combined system
CN109266521A (en) * 2018-09-18 2019-01-25 江门出入境检验检疫局检验检疫技术中心 Pneumatic type multichannel microbiological culture media prepares packing instrument automatically
TWI649418B (en) * 2016-05-27 2019-02-01 健茂生物科技股份有限公司 Inoculation and fermentation equipment
CN109793136A (en) * 2017-11-17 2019-05-24 健茂生物科技股份有限公司 Application apparatus used in the preparation flow of health beverages and the preparation flow
CN109939588A (en) * 2017-12-21 2019-06-28 谢思松 Mix and stir the U-shaped mixing apparatus of expanded perlite
CN111004713A (en) * 2019-12-27 2020-04-14 华中科技大学鄂州工业技术研究院 Culture apparatus for microorganism dynamic growth environment
CN111088080A (en) * 2019-12-19 2020-05-01 南京科泷节能科技有限公司 Energy-saving and environment-friendly gas device and method
CN111847566A (en) * 2020-07-23 2020-10-30 上海乔尼水处理设备工程有限公司 Method and device for treating high-COD wastewater in electronic industry
CN112410222A (en) * 2020-11-03 2021-02-26 江南大学 Multi-chamber bubble tower bioreactor for animal cell culture
CN112604621A (en) * 2020-11-11 2021-04-06 安徽省美极农业科技有限公司 Stainless steel reaction kettle for fertilizer production and use method
CN115215693A (en) * 2022-07-29 2022-10-21 中国科学院广州能源研究所 Assembled paddle of aerobic composting device
CN115226703A (en) * 2022-07-21 2022-10-25 丽水经济技术开发区生态林业发展中心 Forestry drives bird equipment

Cited By (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102836665A (en) * 2012-09-19 2012-12-26 常州大学 Mixing stirrer with paddle with airflow driven by air pressure
CN102895902A (en) * 2012-11-09 2013-01-30 泰山医学院 Hydraulic power driving mixing agitator
CN102895902B (en) * 2012-11-09 2015-05-06 泰山医学院 Hydraulic power driving mixing agitator
CN103834555A (en) * 2013-12-19 2014-06-04 柳州市京阳节能科技研发有限公司 Multifunctional efficient and energy-saving fermentation tank
CN104403929A (en) * 2014-12-21 2015-03-11 遵义联谷农业科技有限公司 Liquid strain fermentation tank
CN105199909A (en) * 2015-10-27 2015-12-30 高州市和友酒业有限公司 High-pressure gas stirring type fermentation tank
CN105695320A (en) * 2015-12-10 2016-06-22 柳州市京阳节能科技研发有限公司 Efficient sanitary environment-friendly fermentation device
CN109954472A (en) * 2016-01-28 2019-07-02 乐清市拓展机械科技有限公司 A kind of device for collecting temperature control and stirring as one
CN105688782A (en) * 2016-01-28 2016-06-22 王海龙 Temperature control and stirring integrated device
CN105688782B (en) * 2016-01-28 2019-02-01 乐清市拓展机械科技有限公司 A kind of device for collecting temperature control and stirring as one
CN109894067A (en) * 2016-01-28 2019-06-18 乐清市拓展机械科技有限公司 Collection temperature control with more blades and the device to stir as one
TWI649418B (en) * 2016-05-27 2019-02-01 健茂生物科技股份有限公司 Inoculation and fermentation equipment
CN106867870A (en) * 2017-04-28 2017-06-20 天津科技大学 A kind of L threonines produce tank and threonine production technology
CN107297192A (en) * 2017-07-27 2017-10-27 浙江长江搅拌设备有限公司 A kind of gas, solid, liquid reaction unit
CN107470039A (en) * 2017-08-01 2017-12-15 鲁南制药集团股份有限公司 A kind of Alcohol-settling tank, horizontal screw centrifuge combined system
CN107354091A (en) * 2017-08-31 2017-11-17 江苏天琦生物科技有限公司 A kind of soya-bean polypeptides enzymolysis device
CN109793136A (en) * 2017-11-17 2019-05-24 健茂生物科技股份有限公司 Application apparatus used in the preparation flow of health beverages and the preparation flow
CN109939588A (en) * 2017-12-21 2019-06-28 谢思松 Mix and stir the U-shaped mixing apparatus of expanded perlite
CN109266521A (en) * 2018-09-18 2019-01-25 江门出入境检验检疫局检验检疫技术中心 Pneumatic type multichannel microbiological culture media prepares packing instrument automatically
CN111088080A (en) * 2019-12-19 2020-05-01 南京科泷节能科技有限公司 Energy-saving and environment-friendly gas device and method
CN111004713A (en) * 2019-12-27 2020-04-14 华中科技大学鄂州工业技术研究院 Culture apparatus for microorganism dynamic growth environment
CN111847566A (en) * 2020-07-23 2020-10-30 上海乔尼水处理设备工程有限公司 Method and device for treating high-COD wastewater in electronic industry
CN112410222A (en) * 2020-11-03 2021-02-26 江南大学 Multi-chamber bubble tower bioreactor for animal cell culture
CN112410222B (en) * 2020-11-03 2022-02-01 江南大学 Multi-chamber bubble tower bioreactor for animal cell culture
CN112604621A (en) * 2020-11-11 2021-04-06 安徽省美极农业科技有限公司 Stainless steel reaction kettle for fertilizer production and use method
CN115226703A (en) * 2022-07-21 2022-10-25 丽水经济技术开发区生态林业发展中心 Forestry drives bird equipment
CN115215693A (en) * 2022-07-29 2022-10-21 中国科学院广州能源研究所 Assembled paddle of aerobic composting device

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Open date: 20070801