CN100998751A - Traditional Chinese medicine decoction for treating radiation pneumonitis - Google Patents
Traditional Chinese medicine decoction for treating radiation pneumonitis Download PDFInfo
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Abstract
The invention relates to the field of medicine formulas, in particular to a traditional Chinese medicine decoction for treating radiation pneumonitis, which is prepared by soaking, decocting and filtering figwort root, dried rehmannia root, dwarf lilyturf tuber, tree peony bark, platycodon root, mint, unibract fritillary bulb, raw liquorice, boat-fruited sterculia seed and heartleaf houttuynia herb serving as raw materials and is characterized in that the raw materials in parts by weight are as follows: 10-20 parts of radix scrophulariae, 10-20 parts of radix rehmanniae, 10-15 parts of radix ophiopogonis, 9-15 parts of cortex moutan, 10-20 parts of platycodon grandiflorum, 6-9 parts of mint, 9-15 parts of fritillaria cirrhosa, 6-10 parts of raw liquorice, 15-20 parts of boat-fruited sterculia seed and 30-45 parts of houttuynia cordata. The formula of the invention has the obvious effects of clearing away heat and toxic materials, nourishing yin, clearing away the lung-heat, cooling blood, promoting the production of body fluid, relieving cough and reducing sputum. After the medicine is taken by patients, the medicine has no toxic or side effect, is suitable for treating the radiation pneumonitis, and has higher treatment effective rate and cure rate.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of Chinese medicine decoction of radiotherapy pneumonia.
Background technology
Malignant tumor has the trend of increasing in worldwide, the sickness rate of China's malignant tumor also increases year by year, and radiotherapy occupies critical role in oncotherapy.In the radiotherapy of breast tumor, inevitably lung tissue is caused damage, there is the patient of 5-15% radiation pneumonia can occur approximately, clinically mainly show as cough, expectoration, that severe patient shows as is uncomfortable in chest, feel suffocated.
At present domestic do not having specific process aspect the radiotherapy pneumonia method, in case it is clinical many based on symptomatic treatment radiation pneumonia to occur, method mainly contains oxygen uptake, uses adrenocortical hormone, uses antibiotic, use expectorant and bronchodilator etc., but effect is unsatisfactory.
Summary of the invention
Chest has many important tissues and organ, in radiation therapy process, inevitably these tissues and organ is caused in various degree damage, produces some radiolesions, and is especially more obvious to lung injury.Radiation pneumonia is a common complication in the breast tumor radiotherapy.In order effectively to overcome the deficiency of existing radiotherapy pneumonia method, especially satisfy radiation pneumonia patient's treatment needs, the present invention by the drug screening of several years and clinical verification repeatedly, provides a kind of Chinese medicine decoction safely and effectively of radiotherapy pneumonia according to theory of Chinese medical science.
The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of Chinese medicine decoction of radiotherapy pneumonia, adopting Radix Scrophulariae, the Radix Rehmanniae, Radix Ophiopogonis, Cortex Moutan, Radix Platycodonis, Herba Menthae, Bulbus Fritillariae Cirrhosae, Radix Glycyrrhizae, Semen Sterculiae Lychnophorae, Herba Houttuyniae is raw material, be prepared into decoction through soaking, decoct, filtering, the weight portion that it is characterized in that raw material is: Radix Scrophulariae 10-20 part, Radix Rehmanniae 10-20 part, Radix Ophiopogonis 10-15 part, Cortex Moutan 9-15 part, Radix Platycodonis 10-20 part, Herba Menthae 6-9 part, Bulbus Fritillariae Cirrhosae 9-15 part, Radix Glycyrrhizae 6-10 part, Semen Sterculiae Lychnophorae 15-20 part, Herba Houttuyniae 30-45 part.
The weight portion preferable range of raw material of the present invention is: 15 parts of Radix Scrophulariaes, 20 parts in the Radix Rehmanniae, 15 parts of Radix Ophiopogonis, 9 parts of Cortex Moutans, 20 parts of Radix Platycodoniss, 6 parts of Herba Menthaes, 12 parts of Bulbus Fritillariae Cirrhosaes, 10 parts of Radix Glycyrrhizae, 15 parts of Semen Sterculiae Lychnophoraes, 30 parts of Herba Houttuyniae, aforementioned base materials makes decoction after mixing immersion, decoction, filtration.
The invention has the beneficial effects as follows: prescription of the present invention has that heat-clearing and toxic substances removing, nourishing YIN and clearing away lung-heat, removing heat from blood promote the production of body fluid, the remarkable efficacy of relieving cough and resolving phlegm.After the patient takes, without any toxic and side effects, be applicable to the treatment of radiation pneumonia, treatment effective percentage and cure rate are higher.
The specific embodiment
The invention will be further described below in conjunction with embodiment:
Embodiment 1:
Present embodiment uses the crude drug of following consumption proportion to be potion: Radix Scrophulariae 15g, Radix Rehmanniae 20g, Radix Ophiopogonis 15g, Cortex Moutan 9g, Radix Platycodonis 20g, Herba Menthae 6g, Bulbus Fritillariae Cirrhosae 12g, Radix Glycyrrhizae 10g, Semen Sterculiae Lychnophorae 15g, Herba Houttuyniae 30g, every pair of medicine adds water 300ml earlier, do not have powder to be advisable, soaked 30 minutes, head is fried in shallow oil every pair of medicine and is fried in shallow oil to 100ml, two fry in shallow oil and add water 300ml again, fry in shallow oil to 100ml, and two fry in shallow oil to be mixed and take, each 50~60ml, every day three times, 15 days is a course of treatment.
The present invention selects for use Radix Scrophulariae, the Radix Rehmanniae, Radix Ophiopogonis, Cortex Moutan, Radix Platycodonis, Herba Menthae, Bulbus Fritillariae Cirrhosae, Radix Glycyrrhizae, Semen Sterculiae Lychnophorae, Herba Houttuyniae to make up, and makes each efficacy of drugs produce synergism after the combination, thus radiotherapy pneumonia effectively.Wherein Radix Scrophulariae sweet in the mouth, hardship, salty are cold in nature.Return lung, stomach, kidney channel.Have clearing away heat and cooling blood, YIN nourishing is removed fire, the effect of detoxicating and resolving stagnation of pathogens.Radix Rehmanniae sweet in the mouth, hardship, cold in nature.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, the effect of YIN nourishing and the production of body fluid promoting.Radix Ophiopogonis sweet in the mouth, little hardship, cold nature.GUIXIN, lung, stomach warp.Have nourishing YIN and moistening the lung, reinforcing stomach reg fluid it, the relieving restlessness that clears away heart-fire, the effect of loosening bowel to relieve constipation.Cortex Moutan bitter in the mouth, suffering, cold nature.Has clearing away heat and cooling blood, the effect of promoting blood circulation to remove blood stasis.Radix Platycodonis bitter in the mouth, suffering, property is flat.Return lung meridian.Has expelling phlegm for arresting cough, lung qi dispersing sore-throat relieving, the effect of removing pus and relieving carbuncle.The Herba Menthae acrid in the mouth, cool in nature.Return lung, Liver Channel.Have relieving the exterior syndrome with drugs of pungent in flavor and cool in nature, the clear sharp head, the effect of dispersing the stagnated live-QI to relieve the stagnation of QI.Bulbus Fritillariae Cirrhosae bitter in the mouth, sweet, cold nature.Return lung, heart channel.Has removing heat-phlegm, the effect of detoxicating and resolving stagnation of pathogens.The Radix Glycyrrhizae sweet in the mouth, property is flat.GUIXIN, lung, spleen, stomach warp.Has the QI invigorating invigorating middle warmer, expelling phlegm for arresting cough, heat-clearing and toxic substances removing, relieving spasm to stop pain, the effect of coordinating the actions of various ingredients in a prescription.The Semen Sterculiae Lychnophorae sweet in the mouth, cold in nature.Return lung, large intestine channel.Has removing heat from the lung and relieving sorethroat, the effect of loosening bowel to relieve constipation.The Herba Houttuyniae acrid in the mouth, cold nature.Return lung, kidney, urinary bladder channel.Has heat-clearing and toxic substances removing, the effect of inducing diuresis for treating stranguria syndrome.All medicine compatibilities play altogether that heat-clearing and toxic substances removing, nourishing YIN and clearing away lung-heat, removing heat from blood promote the production of body fluid, the effect of relieving cough and resolving phlegm.Modern pharmacological research: Radix Scrophulariae has antibiotic, refrigeration function.Radix Rehmanniae aqueous extract and decoct have stronger antiinflammatory action, improve immunologic function; Improve the proliferative amount of bone marrow hematogenesis thousand cells, and radiation injury is had certain protection and promotes repair.Radix Ophiopogonis extract has anti-hypoxia, and the enhance immunity effect has bacteriostasis to the part antibacterial.Cortex Moutan can prevent microthrombusis, and paeonol has effects such as sedation and analgesia, analgesic cooling, and various bacteria is had inhibitory action.The Radix Platycodonis decoct can make the respiratory mucus secretory volume increase, and the action intensity and the mechanism of action are similar to ammonium chloride, and Radix Platycodonis extract has obvious antitussive effect, and the thick Saponin of Radix Platycodonis has antiinflammatory, antiulcer, calmness, analgesia, analgesic, relaxing smooth muscle and immunological enhancement.Bulbus Fritillariae Cirrhosae has antitussive effect, and bronchial smooth muscle is had obvious dilating effect.Radix Glycyrrhizae has antiviral and antibacterial action, and has the adrenocortical hormone effect, has significant antiinflammatory action, can suppress to alleviate various inflammatory reactions.The Semen Sterculiae Lychnophorae water-leach liquor has laxative action to rabbit, also has diuresis, analgesic activity.The Herba Houttuyniae decoct has inhibitory action external to staphylococcus aureus and distortion, typhoid fever, shigella flexneri etc.
But each raw material of the present invention also blended embodiment of the listed ratio of according to the form below (weight portion) is realized.Its processing is identical with embodiment 1, and processing method is the Chinese medicine decocting method that generally uses.
Radix Scrophulariae | The Radix Rehmanniae | Radix Ophiopogonis | Cortex Moutan | Radix Platycodonis | Herba Menthae | Bulbus Fritillariae Cirrhosae | Radix Glycyrrhizae | Semen Sterculiae Lychnophorae | Herba Houttuyniae | |
Embodiment 2 | ?10 | ?10 | ?10 | ?15 | ?10 | ?9 | ?15 | ?6 | ?20 | ?45 |
Embodiment 3 | ?20 | ?20 | ?12 | ?10 | ?15 | ?8 | ?9 | ?8 | ?17 | ?40 |
Embodiment 4 | ?18 | ?15 | ?11 | ?14 | ?18 | ?7 | ?11 | ?7 | ?16 | ?42 |
Embodiment 5 | ?16 | ?17 | ?15 | ?9 | ?19 | ?7 | ?10 | ?10 | ?15 | ?35 |
1, case is selected: clinically select 44 routine patients at random, 44 routine patients all make a definite diagnosis through cytology and/or histopathology, breast CT, are radiocurable first chest malignant tumor patient.Male's 26 examples wherein, women's 18 examples, the man: the woman is 1.44: 1.
2, diagnostic criteria:
(1) radiotherapy history.
(2) irritable cough, carrying out property Velcro rale out of breath and pulmonary have characteristic.
(3) visible pneumonia of chest X-ray or fibrosis performance.
3, Therapeutic Method: with one pair of medicine of the present invention every day, all unifiedly decocted by my the institute chamber of boiling medicine, every pair of medicine adds water 300ml earlier, does not have powder to be advisable, and soaks 30 minutes, fries in shallow oil every pair of medicine and fries in shallow oil to 100ml.Two fry in shallow oil and add water 300ml again, fry in shallow oil to 100ml, and two fry in shallow oil to be mixed and take.Each 50~60ml, every day three times, 15 days is a course of treatment.
4, curative effect is judged:
Cure: clinical symptoms, Signs disappear, and it is normal that the X line recovers.
Take a turn for the better: clinical symptoms, Signs disappear substantially, and X line pathological changes basic absorption is left over a few fibres bar Suo Ying.
Do not heal: clinical symptoms, Signs do not have improvement, and pulmonary shadow does not have absorption, or extensive pulmonary fibrosis performance occurs.
5, therapeutic effect: use the present invention to treat three courses of treatment of 44 examples, the result cures 23 examples, 16 examples that take a turn for the better, and invalid 5 examples, always curing improvement rate is 88.6%.
Claims (2)
1, a kind of Chinese medicine decoction of radiotherapy pneumonia, adopting Radix Scrophulariae, the Radix Rehmanniae, Radix Ophiopogonis, Cortex Moutan, Radix Platycodonis, Herba Menthae, Bulbus Fritillariae Cirrhosae, Radix Glycyrrhizae, Semen Sterculiae Lychnophorae, Herba Houttuyniae is raw material, be prepared into decoction through soaking, decoct, filtering, it is characterized in that the weight portion of raw material is: Radix Scrophulariae 10-20 part, Radix Rehmanniae 10-20 part, Radix Ophiopogonis 10-15 part, Cortex Moutan 9-15 part, Radix Platycodonis 10-20 part, Herba Menthae 6-9 part, Bulbus Fritillariae Cirrhosae 9-15 part, Radix Glycyrrhizae 6-10 part, Semen Sterculiae Lychnophorae 15-20 part, Herba Houttuyniae 30-45 part.
2, according to the Chinese medicine decoction of the described a kind of radiotherapy pneumonia of claim 1, the weight portion that it is characterized in that said raw material is, 15 parts of Radix Scrophulariaes, 20 parts in the Radix Rehmanniae, 15 parts of Radix Ophiopogonis, 9 parts of Cortex Moutans, 20 parts of Radix Platycodoniss, 6 parts of Herba Menthaes, 12 parts of Bulbus Fritillariae Cirrhosaes, 10 parts of Radix Glycyrrhizae, 15 parts of Semen Sterculiae Lychnophoraes, 30 parts of Herba Houttuyniae, aforementioned base materials make decoction after mixing immersion, decoction, filtration.
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Cited By (9)
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CN102188619A (en) * | 2011-04-16 | 2011-09-21 | 姜爱武 | Traditional Chinese medicine for treating radiation pneumonia |
CN101773601B (en) * | 2010-02-03 | 2011-10-19 | 孙成春 | Throat-care granules in bag for treatment of pharyngitis |
CN102614367A (en) * | 2012-03-12 | 2012-08-01 | 迟玉丽 | Herba houttuyniae, radix liriopes, lonicera confusa, arisaema cum bile and rhizoma arisaematis powder for early infantile pneumonia |
EP2608783A1 (en) * | 2010-08-25 | 2013-07-03 | Lurong Zhang | Use of glycyrrhetinic acid, glycyrrhizic acid and related compounds for prevention and/or treatment of pulmonary fibrosis |
CN104398793A (en) * | 2014-10-21 | 2015-03-11 | 鲁桂青 | Traditional Chinese medicine composition for treating radiation pneumonitis and preparation method of traditional Chinese medicine composition |
CN105079432A (en) * | 2015-08-20 | 2015-11-25 | 贵州百草精髓保健酒有限公司 | Traditional Chinese medicine for treating cough |
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