CN100584945C - 调节基因表达的核被膜和核纤层结合嵌合体 - Google Patents

调节基因表达的核被膜和核纤层结合嵌合体 Download PDF

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CN100584945C
CN100584945C CN03802361A CN03802361A CN100584945C CN 100584945 C CN100584945 C CN 100584945C CN 03802361 A CN03802361 A CN 03802361A CN 03802361 A CN03802361 A CN 03802361A CN 100584945 C CN100584945 C CN 100584945C
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protein
domain
proteins
threonine
gene
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CN1617732A (zh
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世良尚
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Syngenta Participations AG
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Syngenta Participations AG
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8217—Gene switch
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/09—Fusion polypeptide containing a localisation/targetting motif containing a nuclear localisation signal
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/80—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
    • C07K2319/81—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor containing a Zn-finger domain for DNA binding

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  • General Chemical & Material Sciences (AREA)
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  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN03802361A 2002-01-18 2003-01-17 调节基因表达的核被膜和核纤层结合嵌合体 Expired - Fee Related CN100584945C (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US35016302P 2002-01-18 2002-01-18
US60/350,163 2002-01-18
US35131502P 2002-01-23 2002-01-23
US60/351,315 2002-01-23
PCT/US2003/001529 WO2003062447A2 (en) 2002-01-18 2003-01-17 Nuclear-envelope and nuclear-lamina binding chimeras for modulating gene expression

Publications (2)

Publication Number Publication Date
CN1617732A CN1617732A (zh) 2005-05-18
CN100584945C true CN100584945C (zh) 2010-01-27

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ID=27616763

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CN03802361A Expired - Fee Related CN100584945C (zh) 2002-01-18 2003-01-17 调节基因表达的核被膜和核纤层结合嵌合体

Country Status (7)

Country Link
US (1) US20050170348A1 (https=)
EP (1) EP1485108A4 (https=)
JP (1) JP2005514957A (https=)
CN (1) CN100584945C (https=)
AU (1) AU2003212816B2 (https=)
CA (1) CA2472729A1 (https=)
WO (1) WO2003062447A2 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1948807B1 (en) * 2005-11-07 2015-09-30 CropDesign N.V. Plants having improved growth characteristics and a method for making the same
US9404123B2 (en) 2011-10-12 2016-08-02 National Centre For Biological Sciences Nucleic acid assembly, vector, cell, methods and kit thereof
CN109112142B (zh) * 2018-07-30 2021-02-12 华中农业大学 OsNMCP1基因在控制水稻耐旱中的应用
CN111793707B (zh) * 2020-06-23 2022-04-22 中国农业科学院油料作物研究所 一种基因编辑转基因作物编辑位点特异性pcr方法及其应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5652340A (en) * 1992-08-21 1997-07-29 La Jolla Cancer Research Foundation Matrix-associating DNA-binding protein, nucleic acids encoding the same and methods for detecting the nucleic acids
US6153729A (en) * 1997-06-20 2000-11-28 St. Jude's Children's Research Hospital Isolated nuclear matrix targeting peptide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6482646B1 (en) * 1998-11-06 2002-11-19 E. I. Du Pont De Nemours And Company Plant proteins that interact with nuclear matrix proteins and function as transcriptional activators

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5652340A (en) * 1992-08-21 1997-07-29 La Jolla Cancer Research Foundation Matrix-associating DNA-binding protein, nucleic acids encoding the same and methods for detecting the nucleic acids
US6153729A (en) * 1997-06-20 2000-11-28 St. Jude's Children's Research Hospital Isolated nuclear matrix targeting peptide

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Publication number Publication date
EP1485108A4 (en) 2006-03-22
CN1617732A (zh) 2005-05-18
CA2472729A1 (en) 2003-07-31
WO2003062447A3 (en) 2004-09-30
EP1485108A2 (en) 2004-12-15
AU2003212816B2 (en) 2008-02-07
WO2003062447A2 (en) 2003-07-31
JP2005514957A (ja) 2005-05-26
US20050170348A1 (en) 2005-08-04

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