CN100567979C - Solid phase extraction tube - Google Patents
Solid phase extraction tube Download PDFInfo
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- CN100567979C CN100567979C CNB2005800105587A CN200580010558A CN100567979C CN 100567979 C CN100567979 C CN 100567979C CN B2005800105587 A CNB2005800105587 A CN B2005800105587A CN 200580010558 A CN200580010558 A CN 200580010558A CN 100567979 C CN100567979 C CN 100567979C
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- extracting tube
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- phase extraction
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Abstract
The invention provides a kind of solid phase extraction tube, it forms the delay that not only can suppress sample or solution as much as possible, and in order to remove impurity or to obtain multiple purpose composition rapidly and the structure that a plurality of solid phase extraction tubes are chimeric.In tubular extracting tube body 1A, from upside, be provided with inflow side sintered plate 3, solid phase filling agent 4 and outflow side sintered plate 5, on the lower end inner face of extracting tube body 1A, setting meets the stop part 1f of retaining outflow side sintered plate, the lower end that is provided with on extracting tube body 1A from its upper end other extracting tube bodies 1A is inserted into assigned position and can keeps its fitting portion that inserts state, fitting portion by the inner face that is formed on the extracting tube body 1A that is inserted into more to big more inboard conical surface 1g of upside diameter and the constituting to the big more outside conical surface of upside diameter more of outside that be formed on the extracting tube body of inserting side.
Description
Technical field
The present invention relates to a kind of solid phase extraction tube, it is used to modulate the sample of analyzing with liquid chromatography or gas chromatography etc.
Background technology
The above-mentioned solid phase extracting tube is in the tubular extracting tube body that upper end and lower end are opened wide, and from upside, is made of inflow side sintered plate, solid phase filling agent and outflow side sintered plate.In the solid phase extraction tube that constitutes like this, for example, sample is injected, the purpose composition that is injected in the sample is retained in the solid phase filling agent from syringe (injector), flow into eluent to the solid phase filling agent that maintains this purpose composition, thereby can reclaim the purpose composition that is concentrated.So, motion has and a kind ofly has the tubular littler than this extracting tube body diameter by tubular extracting tube body of accommodating above-mentioned inflow side sintered plate, solid phase filling agent and outflow side sintered plate and outlet end one side at this extracting tube body and discharge the solid phase extraction tube (for example, with reference to patent documentation 1) that constitutes with first end.
Patent documentation 1: the spy opens 2002-316002 communique (with reference to Fig. 1)
Summary of the invention
According to above-mentioned patent documentation 1, because have dead space with (past more center is offside in the taper of below) stage portion of the mortar shape of an end of first end in the discharge of an outlet end that connects the extracting tube body and a corresponding with it side, sample or solution can be trapped in this dead space, so will cause rough sledding such as purpose constituent concentration reduction, go wrong when perhaps extracting the purpose composition in next stage because of the sample that is detained or solution.
In addition, when in sample, wishing that the purpose composition that keeps has multiple (for example two kinds), perhaps in order to remove the impurity in the sample, need to be provided with multiple (two kinds) solid phase extraction tube with different solid phase filling agents, for example inject sample to the 1st solid phase extraction tube with syringe, container with other syringes etc. receives the draw-off (not by solid phase filling agent material retained) of discharging from this solid phase extraction tube, received draw-off is injected into No. 2 solid phase extraction tube again, therefore operation is very loaded down with trivial details.
In view of the foregoing, the problem to be solved in the present invention provides a kind of delay that structurally not only can suppress sample or solution as much as possible, simultaneously can also be for the solid phase extraction tube of removing impurity or can chimeric (overlapping combination) a plurality of solid phase extraction tubes in order to obtain multiple purpose composition rapidly.
In order to address the above problem, solid phase extraction tube of the present invention is in the tubular extracting tube body that upper end and lower end are opened wide, from upside, have inflow side sintered plate, solid phase filling agent and outflow side sintered plate, the downside inner face of above-mentioned extracting tube body is provided with outstanding to the inside and connects the stop part of blocking the neighboring of stating the outflow side sintered plate continuously or intermittently; Perhaps be formed with the more little cone head part of the past more downside diameter of formation and be used to keep the maintaining part of above-mentioned outflow side sintered plate at the inner face of the downside of above-mentioned extracting tube body, and above-mentioned extracting tube is had from the upper end lower end of other above-mentioned extracting tube bodies is inserted into assigned position and can keeps it to insert the fitting portion of state, above-mentioned fitting portion constitutes by being formed the inboard conical surface that more up diameter is big more at least and being formed the outside conical surface that more up diameter is big more at least in specialized range in the inner face of the above-mentioned extracting tube body that is inserted into side in specialized range in the outside of the extracting tube body of above-mentioned inserting side, and the above-mentioned inboard conical surface and the outside conical surface are formed both and have essentially identical angle of inclination.
As mentioned above, because have continuously and receive intermittently the stop part of the neighboring of outflow side sintered plate in the lower end of extracting tube body, perhaps only be formed with the more little cone head part of the past more downside diameter of formation and be used to keep the maintaining part of above-mentioned outflow side sintered plate at the inner face of the downside of above-mentioned extracting tube body, can not form big dead space at stop part or maintaining part, so sample can be suppressed as much as possible or solution is trapped in stop part or maintaining part.
And, in order to remove impurity maybe when wish keeping multiple purpose composition, by having the conical surface at essentially identical angle of inclination inside and outside utilizing, can a plurality of solid phase extraction tubes with the solid phase filling agent that can keep impurity or purpose composition are chimeric.And, those are in the solid phase extraction tube of chimerism, by syringe etc. sample is injected, make that the multiple purpose composition of wishing the impurity of removing or wishing the to keep injection operation by once just can be kept.
Under the chimerism of above-mentioned two kinds of extracting tube bodies, also can make be positioned at the below the extracting tube body inner face be positioned at the top the extracting tube body the inner face basic comprising for the one side.
When injecting sample, stage portion will appear at the inner face of the chimeric extracting tube body of above-below direction, and therefore all samples can move in the extracting tube body swimmingly, and the phenomenon of a part of sample etc. can not take place to be detained in this stage portion.
Solid phase extraction tube of the present invention also can constitute: above-mentioned extracting tube body by insert in other above-mentioned extracting tube bodies and chimeric with it lower portion and have from this lower portion laterally the upper portion of outstanding outside dimension constitute, under the chimerism of above-mentioned two extracting tube bodies, in the lower portion of the extracting tube body above this and the stage portion of the formation of the boundary between the upper portion, and form the mode in slit between the upper end of the extracting tube body below this, be formed with the stage portion of keeping out of the insertion position that is used to stipulate to be positioned at the extracting tube body above this on the inner face that is positioned at the extracting tube body below this.
Solid phase extraction tube of the present invention can also constitute: the upper end open of above-mentioned extracting tube body is set the outside dimension greater than the lower end of this extracting tube body, be formed approaching more this from the upper end open of above-mentioned extracting tube body to the above-mentioned inner face of keeping out stage portion that is positioned at the below and keep out the more little conical surface of stage portion internal diameter size, the outside of the lower portion of above-mentioned extracting tube body is formed and begins the big more conical surface of approaching more above-mentioned stage portion outside dimension from the lower end.
And above-mentioned stop part can be by constituting at the outstanding to the inside a plurality of teats in the circumferencial direction interval in accordance with regulations of the lower end of above-mentioned extracting tube body inner face.
And,, the short tubular end portion with described stop part that can freely install and remove can be installed in the lower end of above-mentioned extracting tube body.
And the upper end of above-mentioned extracting tube body can be provided with flange part.
According to as above the present invention, because have continuously and receive intermittently the stop part of the neighboring of outflow side sintered plate in the lower end of extracting tube body, perhaps only be formed with the more little cone head part of the past more downside diameter of formation and be used to keep the maintaining part of above-mentioned outflow side sintered plate at the inner face of the downside of above-mentioned extracting tube body, can not form big dead space at stop part or maintaining part, so can suppress sample as much as possible or solution is trapped in stop part or maintaining part, and according to plan the purpose composition be extracted.
And, when removing impurity or wish to keep multiple purpose composition, as long as it is chimeric and inject sample and can finish to have a plurality of solid phase extraction tubes of the solid phase filling agent that can keep impurity or purpose composition, just can finish the operation of removing the impurity of wishing to remove or keeping the multiple purpose composition of wishing to keep rapidly by an implant operation.And, when forming the extracting tube body, carry out the moulding of Any shape easily with synthetic resin, be convenient to manufacture.
According to the present invention, under the chimerism of two kinds of extracting tube bodies, by making the inner face basic comprising of inner face and the extracting tube body that is positioned at the top of the extracting tube body be positioned at the below for one side, when injecting sample, stage portion appears in the inner face at the chimeric extracting tube body of above-below direction, therefore all samples can move in the extracting tube body swimmingly, and the phenomenon of a part of sample etc. can not take place to be detained in this stage portion.
According to the present invention, the extracting tube body be by by insert in other extracting tube bodies and chimeric with it lower portion and have from this lower portion laterally the upper portion of outstanding outside dimension constitute, and under the chimerism of above-mentioned two extracting tube bodies, in the lower portion of the extracting tube body above this and the stage portion of the formation of the boundary between the upper portion, and form the mode in slit between the upper end of the extracting tube body below this, be formed with the stage portion of keeping out of the insertion position that is used to stipulate to be positioned at the extracting tube body above this on the inner face that is positioned at the extracting tube body below this, therefore, can insert the chimerism of removing two kinds of extracting tube bodies about being positioned in the slit like a cork with finger.And, only just can form above-mentioned slit by keeping out stage portion in the inner face formation of extracting tube body, be fixed to the intrinsic method of extracting tube than the blocking part that will form elsewhere, help more manufacturing.
According to the present invention, by the upper end open of extracting tube body being set for outside dimension greater than the lower end of this extracting tube body, to form approaching more this to the above-mentioned inner face of keeping out stage portion that is positioned at the below from the upper end open of extracting tube body and keep out the more little conical surface of stage portion internal diameter size, and the outside of the lower portion of extracting tube body is formed from the lower end begins more near the big more conical surface of stage portion outside dimension, even with respect to downside extracting tube body, some offsets take place in the position of upside extracting tube body, also can be rapidly that both are chimeric, insert operation easily and promptly, thereby realize rapidization of purpose composition extracting operation.
According to the present invention, by constituting stop part by a plurality of teats of giving prominence to the inside at the circumferencial direction interval in accordance with regulations of the lower end of above-mentioned extracting tube body inner face, compare with the situation that forms stop part at the circumferencial direction Zone Full, can further suppress sample or solution is trapped in stop part.
According to the present invention, by lower end the short tubular end portion with described stop part that can freely install and remove is installed at the extracting tube body, so can remove end portion, and from the discharge side end of the extracting tube body inflow side sintered plate of packing into, the solid phase filling agent, behind the sintered plate of outflow side, end portion can be installed on the extracting tube body, like this, than with the inflow side sintered plate, the solid phase filling agent, the outflow side sintered plate inserts and shifts to the method for lower ending opening side respectively from the upper end open of the extracting tube body of long size, can be easy, promptly install and remove operation.
According to the present invention, by upper end flange part is set at the extracting tube body, when under the state of hand-held extracting tube body or using under the state of utensil clamping of hold assembly etc. when sample injected the extracting tube body, even the holding force to extracting tube is little, because above-mentioned flange part plays a part to keep out the prevention parts, cause so can not take place the extracting tube body unexpectedly to move downwards from hand or utensil situation about coming off, therefore very convenient in the use.
Description of drawings
[Fig. 1] is vertical sectional drawing of solid phase extraction tube.
[Fig. 2] is the side view of solid phase extraction tube.
[Fig. 3] is the planimetric map of solid phase extraction tube.
[Fig. 4] shows the vertical sectional drawing of two solid phase extraction tubes under the coincidence status of above-below direction.
[Fig. 5] is the planimetric map of the 2nd solid phase extraction tube.
[Fig. 6] is the vertical sectional drawing that shows the 3rd solid phase extraction tube that does not have flange part.
[Fig. 7] is the vertical sectional drawing of two solid phase extraction tubes under the coincidence status of above-below direction of displayed map 6.
[Fig. 8] shows vertical sectional drawing that spiral structure forms the 4th solid phase extraction tube that can detaching structure is made in the lower end.
[Fig. 9] shows the structure of lower end is made vertical sectional drawing that can pass through the 5th solid phase extraction tube of screw disassembling.
[Figure 10] shows the 6th solid phase extraction tube, (a) is to show the vertical sectional drawings of two solid phase extraction tubes under the above-below direction coincidence status, (b) is the ground plan that shows when the below is watched.
[Figure 11] shows the 7th solid phase extraction tube, (a) is to show the vertical sectional drawings of two solid phase extraction tubes under the above-below direction coincidence status, (b) is the ground plan that shows when the below is watched.
[Figure 12] shows the 8th solid phase extraction tube, (a) is to show the vertical sectional drawings of two solid phase extraction tubes under the above-below direction coincidence status, (b) is the ground plan that shows when the below is watched.
[Figure 13] shows the 9th solid phase extraction tube, (a) is to show the vertical sectional drawings of two solid phase extraction tubes under the above-below direction coincidence status, (b) is the ground plan that shows when the below is watched.
[Figure 14] shows the 10th solid phase extraction tube, (a) is to show the vertical sectional drawings of two solid phase extraction tubes under the above-below direction coincidence status, (b) is the ground plan that shows when the below is watched.
[Figure 15] shows the 11st solid phase extraction tube, (a) is to show the vertical sectional drawings of two solid phase extraction tubes under the above-below direction coincidence status, (b) is the ground plan that shows when the below is watched.
[Figure 16] shows the 12nd solid phase extraction tube, (a) is to show the vertical sectional drawings of two solid phase extraction tubes under the above-below direction coincidence status, (b) is the ground plan that shows when the below is watched.
Reference symbol complete list: 1A extracting tube body; The 1f stop part; The 1F flange part; The 1b upper portion; The 1K upper end open; The 1a lower portion; The 1B inner face; 1 solid phase extraction tube; The 1G outside dimension; The 1g conical surface; 1e keeps out stage portion; 1d keeps out stage portion; 1e keeps out stage portion; The 1c stage portion; 2 syringes; The 2A tip; 3 inflow side sintered plates; 4 solid phase filling agents; The 5A neighboring; 5 outflow side sintered plates; 6 samples; The 7A stop part; 7 bottoms; 7B jut (threaded portion); 8 upside bodies; 8B recess (threaded portion); The S slit.
Embodiment
Fig. 1～Fig. 3 shows a kind of solid phase extraction tube 1 that is used to modulate the sample of analyzing with liquid chromatography or gas chromatography etc.
When this solid phase extraction tube 1 is made of transparent (also translucent or opaque) synthetic resin, in the use with cost on all favourable, but also can constitute by other materials.Fig. 1 shows that the tip 2A of syringe (injector) 2 is about to insert the state of the upper end of solid phase extraction tube 1, from this state after as shown in Figure 4 the tip 2A of syringe 2 is inserted the upper end of solid phase extraction tube 1, by injecting the sample 6 in the syringe 2, in solid phase filling agent 4 described later, can keep desirable purpose composition.Above-mentioned solid phase extracting tube 1 can be handed also and can pass through the clamper clamping.
Above-mentioned solid phase extracting tube 1, the extracting tube body 1A of the tubular that is opened wide by upper end and lower end (ellipse or cornue shape also can) constitutes, in this extracting tube body 1A, set gradually from upside: when receiving sample from above push the inflow side sintered plate 3 of the circular plate type of solid phase filling agent; Reception is filled with the outflow side sintered plate 5 of circular plate type of the solid phase filling agent 4 of volume granule, but as the case may be, and any one that sintered plate (also being referred to as filtrator) 3 or 5 also can only be set operated.
Above-mentioned extracting tube body 1A by extracting tube body 1A that can insert other and lower portion 1a that can be chimeric and have than this lower portion 1a laterally the upper portion 1b of outstanding outside dimension constitute, as shown in Figure 4, at two extracting tube body 1A, under the chimerism of 1A, the stage portion 1c of the approximate horizontal that forms at the lower portion 1a of the extracting tube body 1A above this and the boundary member between the upper portion 1b, and form the mode of slit S between the upper end of the extracting tube body 1A below this, on the inner face of the extracting tube body 1A that will insert, be formed for regulation extracting tube body 1A the insertion position keep out stage portion 1e.
In addition, lower end inner face at above-mentioned extracting tube body 1A, the outstanding to the inside tabular stop part 1f of annular that also receives the neighboring 5A of above-mentioned outflow side sintered plate 5 continuously is set, above-mentioned extracting tube body 1A is had from its upper end to be inserted the lower end of other above-mentioned extracting tube body 1A assigned position and can keep it to insert the recess of state, it is fitting portion, at above-mentioned two extracting tube body 1A, under the chimerism of 1A, with mode simultaneously above-mentioned fitting portion (with reference to Fig. 4) is set with the inner face 1B of the extracting tube body 1A below being positioned at and the inner face 1B basic comprising of the extracting tube body 1A that is positioned at the top.Above-mentioned fitting portion is made of the conical surface of above-mentioned lower portion 1a outside and the conical surface 1g of upper portion 1b inner face, identical by the angle of inclination of the lower portion 1a conical surface and the conical surface 1g of above-mentioned upper portion 1b being constituted the angle of inclination, can and be inserted in the Zone Full between the conical surface 1g of extracting tube body 1A inner face of a side at the outside conical surface 1a of the body 1A of extraction portion that is inserted into and form the surface contact state that does not have the slit, but the angle of inclination of male cone (strobilus masculinus) in also can setting with the line way of contact of only part contact.
As shown in Figure 5, above-mentioned stop part 1f is made of a plurality of juts of the neighboring 5A that accepts above-mentioned outflow side sintered plate 5 intermittently, thereby has the advantage of drain sample, purpose composition and eluent better.In addition, above-mentioned stop part 1f preferably is arranged on the lower end of extracting tube body 1A, and so long as in the lower end, is located at any position and all can.So-called above-mentioned downside is meant the downside of middle body of the lower-upper length of extracting tube body 1A.
As above-mentioned solid phase filling agent 4, for example can adopt: materials such as silica gel, aluminium oxide, octadecyl silica, sodium sulphate, high score subclass exchange resin, also can adopt other materials, the kind of the purpose composition that the impurity that can remove according to hope or wish keeps etc. is done corresponding the selection.
Be set as outside dimension 1G by upper end open 1K greater than the lower end of this extracting tube body 1A with above-mentioned extracting tube body 1A, to form approaching more this to the above-mentioned inner face 1B that keeps out stage portion 1d that is positioned at the below from the upper end open 1K of above-mentioned extracting tube body 1A and keep out the more little conical surface of stage portion 1e one side internal diameter size, the lower end of the extracting tube body 1A of one side (upside) can easily be inserted in the upper end open 1K of another extracting tube body 1A, but can not be the conical surface also but face directly.The outside of the lower portion 1a of above-mentioned extracting tube body 1A is formed and begins the big more conical surface of approaching more above-mentioned stage portion 1c one side outside dimension from the lower end.Identical with the angle of inclination of the conical surface from above-mentioned upper end open 1K to the above-mentioned inner face 1B that keeps out stage portion 1d that is positioned at the below (basic identical also can) be arranged at the angle of inclination of the conical surface of this lower portion 1a, can be chimeric mutually between these two conical surfaces with seamless state.At this, shown by between a plurality of extracting tube body 1A, the 1A of the overlapping combination of above-below direction, only relying on chimeric interfixing of realizing, just can obtain to remove rapidly the situation of fixing advantage, but also can adopt means such as locking further to strengthen fixing between the two.
Fig. 1～Fig. 4 is provided with flange part 1F by the upper end at extracting tube body 1A, hand-held or during with utensil clamping extracting tube body 1A, it can be used as stop part and works to keep out the mobile to the lower side advantage of prevention, but as Figure 6 and Figure 7, also can form the structure that does not have flange part 1F.Because other parts of Figure 6 and Figure 7 are identical with Fig. 1 and Fig. 4's, so adopt prosign.
As Fig. 8 and shown in Figure 9, also can be in the lower end of extracting tube body 8, the end portion 7 that will have the short tubular of above-mentioned stop part 7A is provided with in the mode that can freely install and remove at above-below direction, forms solid shape extracting tube 1.According to this structure, after removing end portion 7, the opening (lower ending opening) that can pass through the discharge side of extracting tube body 8 inserts inflow side sintered plate 3, solid phase filling agent 4 and outflow side sintered plate 5.As above-mentioned mounting or dismounting structure, as shown in Figure 8, can be to tie the spiral structure that threaded portion 7B that the inner face that is incorporated in end portion 7 forms constitutes by the threaded portion 8B that forms in outside, the lower end of extracting tube body 8 and this threaded portion 8B spiral; Perhaps as shown in Figure 9, also can be the latch-up structure that is made of the recess 8B that the inner face at end portion 7 jut 7B that forms and the mode that also can unlock with lockable at this jut 7B form in the outside, lower end of extracting tube body 8, can also be other structure.Above-mentioned jut 7B and recess 8B can be arranged on the whole circumference direction, also can be arranged on a place or the many places of circumferencial direction.Fig. 8 and Fig. 9 keep out stage portion 1e, with the taper that is positioned at the central side below of Fig. 1～shown in Figure 7 to keep out stage portion 1e different, be the shape of horizontal plane.This is because the lower surface of end portion 7 almost is level, and two extracting tube bodies 8 can not produced the slit at fitting portion when chimeric.In addition, Fig. 8 and other parts shown in Figure 9 and Fig. 1's～shown in Figure 7 is identical, so adopt prosign.
As shown in Figure 4, sample 6 in the syringe 2 is infused in above-below direction chimeric two extracting tube body 1A, 1A, make solid phase filling agent 4 respectively, behind the 4 reservation purpose compositions, remove the chimeric of extracting tube body 1A, 1A, inject the purpose composition that eluent is retained with extraction to extracting tube body 1A, 1A respectively afterwards.
Figure 10 (a), (b) expression is up and down overlapping in conjunction with two states that omitted stop part 1f that Fig. 1 represents and the solid phase extraction tube 1 of keeping out stage portion 1e.This solid phase extraction tube 1 is made of tubular extracting tube body 1A and the flange part 1F that forms as one with it in the upper end of this extracting tube body 1A.Tubular extracting tube body 1A has outside 1G and inner face 1B all more to the conical surface of the same tilt of downside diameter more little (big more to the upside diameter more).So, by the conical surface is made in interior outside, insert in the solid phase extraction tube 1 of downside from top solid phase extraction tube 1 with upside, thus, both insertion positions, chimeric back are by both allocation regulations, and formation can keep it to insert the fitting portion of state.Above-mentioned fitting portion is by the conical surface 1g of the inner face 1B upside of an above-mentioned side's extracting tube body 1A and be formed on the outside 1G of downside that has another extracting tube body 1A at same angle of inclination with this conical surface 1g and constitute.At this moment, even the angle of inclination of male cone (strobilus masculinus) has some differences still can implementation and operation in making.Figure 10 (b) be see from below Figure 10 (a) solid phase extraction tube 1 in 1 ground plan.
Figure 11 (a), (b) structure of the stop part 1f of solid phase extraction tube shown in Figure 11 has been omitted in expression.That is the inner face 1B of extracting tube body 1A is made of the conical surface 1g that constitutes above-mentioned fitting portion, more little conical surface 1i of diameter more downwards that faces 1h directly and extend from this lower end of facing 1h directly of extending downwards from the stage portion 1e of the lower end of this conical surface 1g.Therefore, move to the lower end, on conical surface 1i, produce the power of pushing outflow side sintered plate 5, make thus and outflow side sintered plate 5 can be remained on its position to central side by the outflow side sintered plate 5 that will have the outside dimension bigger than lower ending opening.In addition, in order to make outflow side sintered plate 5, need to set outside dimension at the outflow side sintered plate 5 of lower ending opening not from the break-through downwards of lower ending opening portion.In addition, because also be subjected to the material influence of above-mentioned outflow side sintered plate 5, be preferably in the outside dimension of setting outflow side sintered plate 5 on the basis of considering material.
In Figure 12 (a) and (b), except the outside with the extracting tube body 1A of the solid phase extraction tube 1 shown in Figure 11 (a) and (b) formed downward more diameter more little 2 grades of conical surface 1b, 1a, other were all identical.That is than the 2nd conical surface 1a of downside, the 1st conical surface 1b of upside forms the conical surface that has wide-angle at above-below direction.
Figure 13 (a) and (b) represent, the outside 1G of the extracting tube body 1A of the solid phase extraction tube 1 of Fig. 1～shown in Figure 4 is formed more to the big more conical surface of upside diameter, the shape of stop part 1f are formed more offside in the conical surface of inboard to upside, and other parts are all identical.
Above-mentioned solid phase extracting tube 1 also can constitute suction pipe (pipette) type shown in Figure 14 (a) and (b) and Figure 15 (a) and (b).Among Figure 14, the 1st conical surface 1a4 that the outside of extracting tube body 1A is diminished gradually by diameter from the top down, the 1st face 1a3 directly, extend the 2nd more little conical surface 1a2 of diameter from the 1st lower end of facing 1a3 directly more downwards and begin to extend the 3rd more little conical surface 1a1 of diameter more downwards and constitute, but also can adopt other structures from the stage portion 1m of the lower end of the 2nd conical surface 1a2 from what the stage portion 1c of the lower end of the 1st conical surface 1a4 extended downwards.In addition, the inner face of extracting tube body 1A by the 1st conical surface 1g that forms fitting portion, from the stage portion 1e of the lower end of the 1st conical surface 1g extend downwards the 1st face directly 1h, from the 1st face directly the 2nd more little conical surface 1i of the downward more extension diameter of lower end of 1h, extend from the lower ends downward side of the 2nd conical surface 1i the 2nd face 1j directly and constitute from the 2nd the 3rd more little conical surface 1k of the downward more extension diameter in lower end that faces 1j directly, but also can adopt other structures.At this moment, can keep outflow side sintered plate 5 by the 3rd conical surface 1k.
It in Figure 15 (a) and (b) the shape of simplifying than the shape of Figure 14 (a) and (b).That is, the 1st conical surface 1a2 that the outside of extracting tube body 1A is diminished gradually by diameter from the top down and constitute from the 2nd conical surface 1a1 that the stage portion 1m of the lower end of the 1st conical surface 1a2 extends downwards, but also can adopt other structures.In addition, the inner face 1B of extracting tube body 1A by the 1st conical surface 1g that forms fitting portion, from the stage portion 1e of the lower end of the 1st conical surface 1g extend downwards the 1st face 1h directly, extend the 2nd more little conical surface 1i of diameter more downwards from the 1st lower end of facing 1h directly, extend from the lower ends downward side of the 2nd conical surface 1i the 2nd face 1j directly and extend the 3rd more little conical surface 1k of diameter more downwards and constitute from the 2nd lower end of facing 1j directly, but also can adopt other structures.At this moment, by the 3rd conical surface 1k, can keep outflow side sintered plate 5 and inflow side sintered plate 3.
As Figure 16 (a), (b) shown in, above-mentioned solid phase extracting tube 1 also can constitute the injection cast that can inject a large amount of samples.The 1st conical surface 1a4 that the outside of extracting tube body 1A is diminished gradually by diameter from the top down, from more little (angle than above-mentioned the 1st conical surface 1a4 is big) the 2nd conical surface 1a3 of the downward more diameter in the lower end of the 1st conical surface 1a4, from constituting that the lower ends downward of the 2nd conical surface 1a3 is extended near the 3rd more little conical surface 1a2 of the downside diameter of vertical direction, the 4th more little conical surface 1a1 of downward more diameter that begins to extend downwards from the stage portion 1m of the conical surface of the lower end that is formed on the 3rd conical surface 1a2, but also can adopt other structures.In addition, the 1st conical surface 1i that the inner face of extracting tube body 1A is diminished gradually by diameter from the top down, begin to form the 3rd conical surface 1g of fitting portion from more little (angle than above-mentioned the 1st conical surface 1i is big) the 2nd conical surface 1j of the downward more diameter in the lower end of the 1st conical surface 1i, from the lower end of the 2nd conical surface 1j and the 1st face 1k directly and constitute, but also can adopt other structures from what the stage portion 1c of the lower end of the 3rd conical surface 1g extended downwards.At this moment, by being formed on the outstanding to the inside stop part 1f of lower end, can keep outflow side sintered plate 5.
Claims (5)
1. solid phase extraction tube, it from upside, has inflow side sintered plate, solid phase filling agent and outflow side sintered plate in the tubular extracting tube body that upper end and lower end are opened wide, it is characterized in that:
The downside inner face of described extracting tube body is provided with the stop part of the neighboring of giving prominence to and connect continuously or intermittently the described outflow side of retaining sintered plate to the inside,
Described extracting tube body by insert in other described extracting tube bodies and chimeric with it lower portion and have from this lower portion laterally the upper portion of outstanding outside dimension constitute, under the chimerism of described two extracting tube bodies, in the lower portion of the extracting tube body above this and the stage portion of the formation of the boundary between the upper portion, and form the mode in slit between the upper end of the extracting tube body below this, be formed with the stage portion of keeping out of the insertion position that is used to stipulate to be positioned at the extracting tube body above this on the inner face that is positioned at the extracting tube body below this, and, under the chimerism of described two extracting tube bodies, the inner face of the extracting tube body below being positioned at is together simultaneously with the inner face basic comprising of the extracting tube body that is positioned at the top.
2. solid phase extraction tube as claimed in claim 1, it is characterized in that: the upper end open of described extracting tube body is set the outside dimension greater than the lower end of this extracting tube body, be formed approaching more this from the upper end open of described extracting tube body to the described inner face of keeping out stage portion that is positioned at the below and keep out the more little conical surface of stage portion internal diameter size, the outside of the lower portion of described extracting tube body is formed the big more conical surface of approaching more described stage portion outside dimension from the lower end.
3. solid phase extraction tube as claimed in claim 1 is characterized in that: described stop part is by constituting at the outstanding to the inside a plurality of teats in the circumferencial direction interval in accordance with regulations of the lower end of described extracting tube body inner face.
4. solid phase extraction tube as claimed in claim 3 is characterized in that: in the lower end of described extracting tube body, the short tubular end portion with described stop part that can freely install and remove is installed.
5. as any one described solid phase extraction tube of claim 1～4, it is characterized in that: the upper end at described extracting tube body is provided with flange part.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004105309 | 2004-03-31 | ||
| JP105309/2004 | 2004-03-31 | ||
| JP293613/2004 | 2004-10-06 |
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| Publication Number | Publication Date |
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| CN1938585A CN1938585A (en) | 2007-03-28 |
| CN100567979C true CN100567979C (en) | 2009-12-09 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2005800105587A Active CN100567979C (en) | 2004-03-31 | 2005-03-24 | Solid phase extraction tube |
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| CN (1) | CN100567979C (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101732888B (en) * | 2010-01-25 | 2012-09-05 | 郜洪文 | Method for extracting trace substances in field and portable solid-phase extractor |
| CN102078705B (en) * | 2010-12-28 | 2012-11-07 | 苏州先伟纳米技术有限公司 | Tandem nano fiber solid phase extraction column |
| CN102836571A (en) * | 2011-06-20 | 2012-12-26 | 苏州赛分科技有限公司 | Solid-phase extraction apparatus |
| CN102841148A (en) * | 2011-06-20 | 2012-12-26 | 苏州赛分科技有限公司 | Switch cannula for solid- phase extraction column |
| CN103439171B (en) * | 2013-08-06 | 2015-11-18 | 李晓亚 | The online solid phase film extraction device of a kind of Portable field |
| DE212021000190U1 (en) * | 2021-10-17 | 2022-01-25 | Nantong Taiying New Material Science and Technology Co., Ltd. | Enrichment tubes for the enrichment of total alkaloids in the extract of thorn apple flowers and leaves |
| DE212021000151U1 (en) * | 2021-10-17 | 2022-01-03 | Nantong Taiying New Material Science and Technology Co., Ltd. | Enrichment tubes for enriching the total flavonoids in bamboo and cypress leaf extract |
| DE212021000191U1 (en) * | 2021-10-17 | 2022-01-19 | Nantong Taiying New Material Science and Technology Co., Ltd. | Enrichment tube for enriching total flavonoids in Narcissus flower and leaf extract |
| DE212021000175U1 (en) * | 2021-10-22 | 2022-01-03 | Nantong Youyuan art design Co.,Ltd. | Enrichment tube for enriching total flavonoids in leek seed extract |
| WO2023065265A1 (en) * | 2021-10-22 | 2023-04-27 | 南通优元美术图案设计有限公司 | Enrichment tube for enriching total flavonoids in houttuynia cordata extraction solution |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1085319A (en) * | 1992-09-03 | 1994-04-13 | 惠普公司 | Solid phase extration apparatus |
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2005
- 2005-03-24 CN CNB2005800105587A patent/CN100567979C/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1085319A (en) * | 1992-09-03 | 1994-04-13 | 惠普公司 | Solid phase extration apparatus |
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| CN1938585A (en) | 2007-03-28 |
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