CN100566733C - A kind of external Chinese medicine for the treatment of acne and preparation method thereof - Google Patents

A kind of external Chinese medicine for the treatment of acne and preparation method thereof Download PDF

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CN100566733C
CN100566733C CNB2007101068853A CN200710106885A CN100566733C CN 100566733 C CN100566733 C CN 100566733C CN B2007101068853 A CNB2007101068853 A CN B2007101068853A CN 200710106885 A CN200710106885 A CN 200710106885A CN 100566733 C CN100566733 C CN 100566733C
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parts
radix
acne
chinese medicine
crude drug
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CN101049381A (en
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佟家勇
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Abstract

The invention discloses a kind of external Chinese medicine for the treatment of acne, be to make by Radix Scutellariae, Cortex Phellodendri, Rhizoma Coptidis, Cortex Dictamni, Fructus Cnidii, Flos Chrysanthemi Indici, Herba Patriniae, Herba Violae, Fructus Gardeniae, Radix Et Rhizoma Rhei, the Radix Rehmanniae, Radix Paeoniae Rubra, Radix Cirsii Japonici, Cacumen Platycladi, to the pathogen usually intruding into collateral in protracted disease person, also can add a certain amount of Spina Gleditsiae.The present composition is according to traditional Chinese medical science heat-clearing and toxic substances removing, dampness, invigorate blood circulation, the principle of removing heat from blood, blood stasis dispelling softening the hard mass and anti-inflammation, by the synergism of said components, acne treated.This medicine for external use uses simple, stable curative effect, there is not recurrence, slight acne can be fully recovered about 30 days, the moderate acne can be fully recovered about 45 days, severe person can fully recover about 60 days, by clinical observation to 100 routine patients with acne, and effective percentage 100% of the present invention, cure rate 85%, solved existing Retinoids, Retin-A, Renova, Accutane treatment time long, curative effect not significantly, easily recurrence and human body is had the problem of certain side effect.

Description

A kind of external Chinese medicine for the treatment of acne and preparation method thereof
Technical field
The present invention relates to a kind of external Chinese medicine, particularly a kind of external Chinese medicine that is exclusively used in the treatment acne.The invention still further relates to described external preparation method of Chinese medicine.
Background technology
Acne claims " comedo ", " skin sore ", " acne " again, is a kind of difficult healing, the dermatosis that sickness rate is very high.Doctor trained in Western medicine thinks that acne is a kind of inertia diseases associated with inflammation with the hair follicle sebum structure multifactor, that the pleomorphism erythra is feature, mainly grow in adolescence's face, breast, the more rich position of back sebaceous gland, show as acne, inflammation pimple, pustule, tuberosity, cyst and cicatrix.The cause of disease of acne mainly contains: bacterial infection, as the infection of corynebacterium acnes; Dyshormonia improves as the androgen level; Metabolism disorder, vigorous as the fat secretion; Gastroenteropathy etc.The traditional Chinese medical science thinks that this disease is, blood stasis dry by the damp and hot blood skin that stagnates, and drinking and eating irregularly is eaten delicious food savoury, pungent well in addition, Chong and Ren channel disorder, disturb on the lung stomach-fire is contained women's head-ornaments or because of taste have damp and hot due to.
The method of integrative therapy acne is Drug therapy at present.Doctor trained in Western medicine is mainly used retinoid compounds to the non-inflammation remedy of acne, as dimension A emulsifiable paste, or adopts antiandrogen class medicine, as spironolactone etc.; Struvite remedy of acne is mainly adopted antibiotic such as erythromycin, spiramycin etc.The medicine that the traditional Chinese medical science adopts mainly is oral medicines such as heat-clearing and toxic substances removing, hard masses softening and resolving class decoction, pill, powder.
In existing, the subject matter that exists of western medical treatment method is:
1. cure rate is lower.Certain effect is arranged during medication often, occur repeatedly after the drug withdrawal.
2. certain side effect is arranged.After part patient's medication untoward reaction is arranged, weak etc. as menoxenia, limbs.
3. the course of treatment is longer.Be generally 3-6 month.
Summary of the invention
The useful very early Chinese medicine of China's medical science fry in shallow oil soup become soaked with sweat wash the treatment dermopathic method, the objective of the invention is by learning the experience of first human therapy acne, according to mechanism, the pharmacological property of modern's acne morbidity and the principle of taking stopgap measures and effecting a permanent cure, by the theories of Chinese materia medica meticulous prescription that skims the cream off milk, for people provide a kind of Chinese medicine topical composition of more effectively treating acne, so that improve the cure rate of this disease, the course of treatment is shortened in the untoward reaction when eliminating medication.The objective of the invention is to realize by following technical scheme:
A kind of external Chinese medicine for the treatment of acne is provided, and it is made by the crude drug of following parts by weight:
Radix Scutellariae 8-10 part, Cortex Phellodendri 8-10 part, Rhizoma Coptidis 8-10 part, Cortex Dictamni 8-10 part, Fructus Cnidii 6-8 part, Flos Chrysanthemi Indici 6-8 part, Herba Patriniae 8-10 part, Herba Violae 8-10 part, Fructus Gardeniae 8-10 part, Radix Et Rhizoma Rhei 10-12 part, Radix Rehmanniae 8-10 part, Radix Paeoniae Rubra 8-10 part, Radix Cirsii Japonici 8-10 part, Cacumen Platycladi 8-10 part, Spina Gleditsiae 0-6 part.
Described external Chinese medicine is preferably made by the crude drug of following parts by weight:
8 parts of Radix Scutellariaes, 8 parts of Cortex Phellodendris, 8 parts of Rhizoma Coptidis, 8 parts of Cortex Dictamni, 6 parts of Fructus Cnidiis, 6 parts of Flos Chrysanthemi Indicis, 8 parts of Herba Patriniae, 8 parts of Herba Violaes, 8 parts of Fructus Gardeniaes, 10 parts of Radix Et Rhizoma Rhei, 8 parts in the Radix Rehmanniae, 8 parts of Radix Paeoniae Rubra, 8 parts of Radix Cirsii Japonicis, 8 parts of Cacumen Platycladis.
Described external Chinese medicine is more preferably made by the crude drug of following parts by weight:
8 parts of Radix Scutellariaes, 8 parts of Cortex Phellodendris, 8 parts of Rhizoma Coptidis, 8 parts of Cortex Dictamni, 6 parts of Fructus Cnidiis, 6 parts of Flos Chrysanthemi Indicis, 8 parts of Herba Patriniae, 8 parts of Herba Violaes, 8 parts of Fructus Gardeniaes, 10 parts of Radix Et Rhizoma Rhei, 8 parts in the Radix Rehmanniae, 8 parts of Radix Paeoniae Rubra, 8 parts of Radix Cirsii Japonicis, 8 parts of Cacumen Platycladis, 6 parts of Spina Gleditsiaes.
The present invention also provides a kind of external preparation method of Chinese medicine of above-mentioned treatment acne, may further comprise the steps:
1) with the crude drug of described ratio with the gauze bag splendid attire and seal;
2) step 1) is put into marmite with the crude drug of gauze medicated bag splendid attire, steeped 1 hour with crude drug weight 8-10 water logging doubly;
3) with step 2) medicated bag that soaked boils with marmite, treat that water is opened after, slow fire was endured 20-30 minute, made.
In the Chinese medicine preparation of the present invention, Herba Patriniae, Flos Chrysanthemi Indici and Herba Violae heat-clearing and toxic substances removing; Radix Scutellariae, Cortex Phellodendri, Rhizoma Coptidis, Fructus Gardeniae and Radix Et Rhizoma Rhei clearing up internal heat by using drugs of bitter in taste and cold in nature; Cortex Dictamni, Fructus Cnidii dampness removing to stop itchin; The Radix Rehmanniae, Radix Paeoniae Rubra, Radix Cirsii Japonici and Cacumen Platycladi removing heat from blood and promoting blood circulation; All medicine synergism complement each other, and to treating the acne of various degree, eliminate corresponding symptom and have good result.Wherein, Flos Chrysanthemi Indici and Fructus Cnidii are slightly poisonous, and consumption is unsuitable excessive.In addition, Spina Gleditsiae has detumescence poison holding, evacuation of pus, parasiticidal drug effect, and for the patient of pathogen usually intruding into collateral in protracted disease, it is better to add the Spina Gleditsiae effect in the side as one feels fit.
Using method of the present invention and effective evaluation:
One, using method of the present invention:
The affected part is cleaned earlier, dipped in the medicinal liquid fomentation that newly boils according to the various embodiments of the present invention method, become soaked with sweat and wash the affected part with fur towel then, every day 2 times, each 30 minutes, respectively 1 time sooner or later with warm water.Diet suffering during the medication, peppery, raw meat, baked foods and drinks.
Two, pharmacological effect of the present invention:
Heat-clearing and toxic substances removing, dampness, blood circulation promoting and blood stasis dispelling, hard masses softening and resolving, YIN nourishing removing heat from blood, anti-inflammation detumescence.
Three, the present invention cure, effective and invalid discrimination standard:
1, cure: disease symptoms is pimple, pustule, tuberosity, cyst, pigmentation complete obiteration.
2, effective: above-mentioned disease symptoms disappearance rate is at least 50%.
3, invalid: above-mentioned disease symptoms does not change.
Four, the present invention can cure time limit and invalid observation period:
1. can cure the time limit:
Can cure the time limit is one group of statistical data, and it is meant that the patient is from using the general therapeutic time limit till the present invention begins to can obtain curative effect the time.The present invention is 20-60 days in this time limit.
2. the invalid observation period:
This time limit is meant that the patient is from using the time limit till the present invention begins when confirming the present invention to the readily good therapeutic effect of patient.The present invention is 3-7 days the invalid observation period.
Five, cure rate of the present invention, effective percentage and inefficiency statistical method and result thereof:
1, selects the test group patient
Select different men and women patient 100 people of severe extent.Wherein, the patient that the state of an illness is lighter is that disease sites only has tiny pimple and pustule person 20 people; The state of an illness is medium to be that disease sites has pimple, pustule and tuberosity person 25 people; The state of an illness is heavier to be that disease sites has pimple, pustule, tuberosity, cyst, pigmentation person 55 people.All patient's age scopes are not wait in 14-30 year.
2, treatment and statistics principle
The medicine that all only prepares with the embodiment of the invention 1 in the test group patient treatment process is a medicine, and all according to above-mentioned using method medication.This group test determines that patient's cure rate, efficient final time are after the medication 60 days; Determine that the inefficient final time is after the medication 7 days.At last by healing, effective and invalid discrimination standard evaluation therapeutic effect.
3, efficacy result statistical result
Healing number: 85 people
Effective number: 15 people
Invalid number: 0 people
Cure rate: 85%
Effective percentage: 100%
Inefficiency: 0%
The present invention finds no any side effect in tentative clinical use.
Beneficial effect:
The present invention compared with prior art has the following advantages:
1. the cure rate height can reach more than 85% usually, and more the back is difficult for recurrence.
2. treat without any side effects.The like product of Xiao Shouing has the decortication phenomenon after as usefulness such as dimension A emulsifiable pastes in the market; Other similar medicines also can produce as adverse side effect such as menoxenia, limbs be weak.
3. short treating period, instant effect, healing period only is 20-60 days usually.And related drugs healing period commonly used at present is 3-6 month.
4. curative effect is compared with existing sulphur ointment more comprehensively, has strengthened the YIN nourishing removing heat from blood, blood circulation promoting and blood stasis dispelling, the function of expelling wind and removing dampness.
5. the invention belongs to medicine for external use, use easy to operate, the medication no pain.
The specific embodiment
Below in conjunction with embodiment, the present invention is done explanation in further detail.
Embodiment 1. preparation embodiment
A. get the raw materials ready
Grasp Radix Scutellariae 8g from pharmacy, Cortex Phellodendri 8g, Rhizoma Coptidis 8g, Cortex Dictamni 8g, Fructus Cnidii 6g, Flos Chrysanthemi Indici 6g, Herba Patriniae 8g, Herba Violae 8g, Fructus Gardeniae 8g, Radix Et Rhizoma Rhei 10g, Radix Rehmanniae 8g, Radix Paeoniae Rubra 8g, Radix Cirsii Japonici 8g, Cacumen Platycladi 8g, 14 flavor medicines are 110g altogether.
Above-mentioned Chinese medicine is packed in the gauze bag, and it is standby that bag mouth is sewed it up.Buy a soft towel from regular supermarket, dry standby after the cleaning.
B. boil
Buy a marmite that decocts Chinese medicine by boiling and simmering from pharmacy; With cleaning inside and outside marmite, the pot cover, contained water 1000g, the gauze pocket that Chinese medicine is housed is put into marmite soaked 1 hour before decocting medicinal herbs; Then marmite is placed on the fire, gets medium and small fire after water is endured out, guarantee pot cover take from after, the water surface keeps boiling; Slow fire is endured and was closed fire in 20 to 30 minutes, promptly makes Chinese herbs decoction of the present invention, uses for 2 times on the 1st.
Embodiment 2. preparation embodiment
A. get the raw materials ready
Grasp Radix Scutellariae 10g from pharmacy, Cortex Phellodendri 10g, Rhizoma Coptidis 10g, Cortex Dictamni 10g, Fructus Cnidii 8g, Flos Chrysanthemi Indici 8g, Herba Patriniae 10g, Herba Violae 10g, Fructus Gardeniae 10g, Radix Et Rhizoma Rhei 12g, Radix Rehmanniae 10g, Radix Paeoniae Rubra 10g, Radix Cirsii Japonici 10g, Cacumen Platycladi 10g, 14 flavor medicines are 138g altogether.
Above-mentioned Chinese medicine is packed in the gauze bag, and it is standby that bag mouth is sewed it up.Buy a soft towel from regular supermarket, dry standby after the cleaning.
B. boil
Buy a marmite that decocts Chinese medicine by boiling and simmering from pharmacy; With cleaning inside and outside marmite, the pot cover, contained water 1300g, the gauze pocket that Chinese medicine is housed is put into marmite soaked one hour before decocting medicinal herbs; Then marmite is placed on the fire, gets medium and small fire after enduring out, guarantee pot cover take from after, the water surface keeps boiling; Slow fire is endured and was closed fire in 20 to 30 minutes, promptly makes Chinese herbs decoction of the present invention.Use for 1 day 2 times.
Embodiment 3. preparation embodiment
A. get the raw materials ready
Grasp Radix Scutellariae 9g from pharmacy, Cortex Phellodendri 9g, Rhizoma Coptidis 9g, Cortex Dictamni 9g, Fructus Cnidii 7g, Flos Chrysanthemi Indici 7g, Herba Patriniae 9g, Herba Violae 9g, Fructus Gardeniae 9g, Radix Et Rhizoma Rhei 11g, Radix Rehmanniae 9g, Radix Paeoniae Rubra 9g, Radix Cirsii Japonici 9g, Cacumen Platycladi 9g, Spina Gleditsiae 6g, 15 flavor medicines are 130g altogether.
Above-mentioned Chinese medicine is packed in the gauze bag, and it is standby that bag mouth is sewed it up.Buy a soft towel from regular supermarket, dry standby after the cleaning.
B. boil
Buy a marmite that decocts Chinese medicine by boiling and simmering from pharmacy; With cleaning inside and outside marmite, the pot cover, contained water 1300g, the gauze pocket that Chinese medicine is housed is put into marmite soaked one hour before decocting medicinal herbs; Then marmite is placed on the fire, gets medium and small fire after enduring out, guarantee pot cover take from after, the water surface keeps boiling; Slow fire is endured and was closed fire in 20 to 30 minutes, promptly makes Chinese herbs decoction of the present invention.Use for 1 day 2 times.
Embodiment 4. Application Examples
A experimenter
Name: Guo Wen sex: woman's age: 20 years old
October 16 2003 the inquiring time first time
Main suit: facial heating, red and swollen, the pain of itching, scleroma is arranged
Diagnostic result: facial acne
Prescription: use the treatment by Chinese herbs of the embodiment of the invention, 20 days courses of treatment
Prepare the gauze medicated bag of preparation among 20 bags of embodiment 1 altogether, every bag of institute's Chinese herbs decoction that boils uses for 1 day 2 times.Before each medication, boil medicinal liquid according to embodiment 1 described boiling method.With warm water face being cleaned the back dips in a pot inner liquid medicine fomentation, becomes soaked with sweat and wash the affected part with fur towel.Every day 2 times, each 30 minutes, sooner or later each once, diet suffering during the medication, peppery, raw meat, baked foods and drinks.
Investigation: investigate the result after half a year, recurrence is not seen in the disease complete obiteration.
B experimenter
Name; Open outstanding sex: man's age: 26 years old.
July 8 2004 the inquiring time first time
The main suit: face has scleroma, cyst, the pain of itching, and with dimension A emulsifiable paste, treats 20 days, and the decortication phenomenon is arranged, and does not see to be clearly better, and occurs repeatedly after the drug withdrawal.
Diagnostic result: facial acne
Prescription: use the present invention's treatment, 30 days courses of treatment.
Prepare the gauze medicated bag of preparation among 30 bags of embodiment 1 altogether, every bag of institute's Chinese herbs decoction that boils uses for 1 day 2 times.Before each medication, boil medicinal liquid according to embodiment 1 described boiling method.With warm water face is cleaned the back and dip in a pot inner liquid medicine fomentation, become soaked with sweat and wash the affected part with fur towel, every day 2 times, each 30 minutes, sooner or later respectively once, totally 30 days.Diet suffering during the medication, peppery, raw meat, baked foods and drinks.
Investigation: investigate the result after 1 year: the symptom complete obiteration, do not see recurrence.
C experimenter
Name: appoint gold ring sex: woman's age: 27 years old
2005 inquiring time JIUYUE is 7 for the first time
The main suit: suffer from acne and had a surplus in 2 years, existing face is itched pain unbearably, skin-tightening, heating.Once controlled with Chinese medicine decoction, effect is not good enough, limbs fatigue after the medication.
Indagation: patient's face has abscess, tuberosity, cyst, cicatrix, pigmentation.
Diagnostic result: severe acne
Prescription: use the present invention's treatment, 35 days courses of treatment
Prepare the gauze medicated bag of preparation among 35 bags of embodiment 3 altogether, every bag of institute's Chinese herbs decoction that boils uses for 1 day 2 times.Before each medication, boil medicinal liquid according to embodiment 1 described boiling method.With warm water face is cleaned the back and dip in a pot inner liquid medicine fomentation, become soaked with sweat and wash the affected part with fur towel, every day 2 times, each 30 minutes, sooner or later respectively once, totally 35 days.Diet suffering during the medication, peppery, raw meat, baked foods and drinks.
October 12 2005 the inquiring time second time
The main suit: the state of an illness is clearly better, and does not have any untoward reaction.
Diagnostic result: facial acne, symptom is most of to disappear.
Prescription: continue to use the present invention's treatment, 25 days courses of treatment.Usage is the same.
Investigation: investigate the result after half a year, recurrence is not seen in the disease complete obiteration.

Claims (4)

1. external Chinese medicine for the treatment of acne is characterized in that it is to be made by the crude drug of following each parts by weight:
Radix Scutellariae 8-10 part, Cortex Phellodendri 8-10 part, Rhizoma Coptidis 8-10 part, Cortex Dictamni 8-10 part, Fructus Cnidii 6-8 part, Flos Chrysanthemi Indici 6-8 part, Herba Patriniae 8-10 part, Herba Violae 8-10 part, Fructus Gardeniae 8-10 part, Radix Et Rhizoma Rhei 10-12 part, Radix Rehmanniae 8-10 part, Radix Paeoniae Rubra 8-10 part, Radix Cirsii Japonici 8-10 part, Cacumen Platycladi 8-10 part, Spina Gleditsiae 0-6 part.
2. according to the external Chinese medicine of the described treatment acne of claim 1, it is characterized in that described crude drug comprises:
8 parts of Radix Scutellariaes, 8 parts of Cortex Phellodendris, 8 parts of Rhizoma Coptidis, 8 parts of Cortex Dictamni, 6 parts of Fructus Cnidiis, 6 parts of Flos Chrysanthemi Indicis, 8 parts of Herba Patriniae, 8 parts of Herba Violaes, 8 parts of Fructus Gardeniaes, 10 parts of Radix Et Rhizoma Rhei, 8 parts in the Radix Rehmanniae, 8 parts of Radix Paeoniae Rubra, 8 parts of Radix Cirsii Japonicis, 8 parts of Cacumen Platycladis.
3. according to the external Chinese medicine of the described treatment acne of claim 2, it is characterized in that also comprising in the described crude drug 6 parts of Spina Gleditsiaes.
4. the external preparation method of Chinese medicine of the described treatment acne of claim 1 may further comprise the steps:
1) with the crude drug of described ratio with the gauze bag splendid attire and seal;
2) step 1) is put into marmite with the crude drug of gauze medicated bag splendid attire, steeped 1 hour with crude drug weight 8-10 water logging doubly;
With step 2) medicated bag that soaked boils with marmite, treat that water is opened after, slow fire is endured and was made in 20-30 minute.
CNB2007101068853A 2007-05-14 2007-05-14 A kind of external Chinese medicine for the treatment of acne and preparation method thereof Expired - Fee Related CN100566733C (en)

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Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101890117B (en) * 2010-07-19 2012-02-01 伍平 Traditional Chinese medicinal composition for treating acnes
CN104840999A (en) * 2014-08-19 2015-08-19 张秀华 Sponge preparation for arresting bleeding of trauma
CN104826004A (en) * 2015-04-28 2015-08-12 余国安 Acne and speckle eliminating drug and preparation method thereof
CN104958652A (en) * 2015-07-10 2015-10-07 澹钊 Acne removing lotion, acne removing medicine composition and preparation method of acne removing medicine composition
CN105998232B (en) * 2016-05-23 2019-12-20 四川省中医药科学院 Application of paliurus ramosissimus or extract thereof in preparation of medicine for treating acne
CN116850122A (en) * 2023-08-24 2023-10-10 中养科技(广东)有限公司 Antibacterial acne-removing composition and preparation method and application thereof

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寻常痤疮当代名医辨治经验体会. 钱江等.中国美容医学,第15卷第4期. 2006
寻常痤疮当代名医辨治经验体会. 钱江等.中国美容医学,第15卷第4期. 2006 *

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