CN100554254C - 用于合成紫杉烷类药物侧链的噁唑烷化合物及制备方法 - Google Patents
用于合成紫杉烷类药物侧链的噁唑烷化合物及制备方法 Download PDFInfo
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- CN100554254C CN100554254C CNB2007100985484A CN200710098548A CN100554254C CN 100554254 C CN100554254 C CN 100554254C CN B2007100985484 A CNB2007100985484 A CN B2007100985484A CN 200710098548 A CN200710098548 A CN 200710098548A CN 100554254 C CN100554254 C CN 100554254C
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- oxazolidine
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CNB2007100985484A CN100554254C (zh) | 2007-04-20 | 2007-04-20 | 用于合成紫杉烷类药物侧链的噁唑烷化合物及制备方法 |
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CNB2007100985484A CN100554254C (zh) | 2007-04-20 | 2007-04-20 | 用于合成紫杉烷类药物侧链的噁唑烷化合物及制备方法 |
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CN101033216A CN101033216A (zh) | 2007-09-12 |
CN100554254C true CN100554254C (zh) | 2009-10-28 |
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CNB2007100985484A Expired - Fee Related CN100554254C (zh) | 2007-04-20 | 2007-04-20 | 用于合成紫杉烷类药物侧链的噁唑烷化合物及制备方法 |
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Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6205530B2 (ja) * | 2015-07-07 | 2017-09-27 | 忠勝 萬代 | パクリタキセル及びドセタキセルの側鎖前駆体の製造方法 |
CN106117058A (zh) * | 2016-06-30 | 2016-11-16 | 山东诚汇双达药业有限公司 | 一种氯乙酸薄荷醇酯的精制方法 |
CN111100026A (zh) * | 2019-12-30 | 2020-05-05 | 重庆市碚圣医药科技股份有限公司 | 一种紫杉醇恶唑环侧链中间体的制备方法 |
CN114621985B (zh) * | 2020-12-10 | 2024-04-16 | 湖南引航生物科技有限公司 | 一种生物催化合成紫杉醇侧链的方法 |
CN114621986B (zh) * | 2020-12-10 | 2024-04-12 | 湖南引航生物科技有限公司 | 一种生物合成紫杉醇侧链的方法 |
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2007
- 2007-04-20 CN CNB2007100985484A patent/CN100554254C/zh not_active Expired - Fee Related
Non-Patent Citations (13)
Title |
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Asymmetric epoxidation of cis-alkenes with arabinose-derivedketones:enantioselective synthesis of the side chain of Taxol. Tony K.M.Shing et al.Tetrahedron,Vol.62 . 2006 |
Asymmetric epoxidation of cis-alkenes with arabinose-derivedketones:enantioselective synthesis of the side chain of Taxol. Tony K.M.Shing et al.Tetrahedron,Vol.62. 2006 * |
Improved protection and esterification of a precursor of thetaxotere and taxol side chains. A.Commercon et al.Tetrahedron Letters,Vol.33 No.36. 1992 |
Improved protection and esterification of a precursor of thetaxotere and taxol side chains. A.Commercon et al.Tetrahedron Letters,Vol.33 No.36. 1992 * |
Semisymthesis of taxol: a highly enantio- anddiastereoselective synthesis of the side chain and a newmethod for ester fornation at C13 using thioesters. Cesare Gennari et al.Angew.Chem.Int.Ed.Engl.,Vol.35 No.15. 1996 |
Semisymthesis of taxol: a highly enantio-anddiastereoselective synthesis of the side chain and a newmethod for ester fornation at C13 using thioesters. Cesare Gennari et al.Angew.Chem.Int.Ed.Engl.,Vol.35 No.15. 1996 * |
立体控制合成紫杉醇侧链丙酮化合物. 刘志煜等.化学学报,第55卷. 1997 |
立体控制合成紫杉醇侧链丙酮化合物. 刘志煜等.化学学报,第55卷. 1997 * |
立体选择性合成紫杉醇C-13侧链. 周忠强等.现代化工,第25卷第1期. 2005 |
紫杉醇C13边链的合成. 赵亚婷等.中国药科大学学报,第37卷第3期. 2006 |
紫杉醇的化学半合成研究. 杨培明.中国医药工业杂志,第27卷第2期. 1996 |
紫杉醇的半合成. 岳琴等.药学学报,第31卷第12期. 1996 |
苏型-N-苯甲酰基-3-苯基异丝氨酸甲酯的合成. 周忠强等.应用化学,第18卷第4期. 2001 |
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Publication number | Publication date |
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CN101033216A (zh) | 2007-09-12 |
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Denomination of invention: Oxazolidine compound for synthesizing taxone pharmaceutical side-chain and preparation method thereof Effective date of registration: 20111027 Granted publication date: 20091028 Pledgee: Beijing's first investment Company Limited by Guarantee Pledgor: Beijing Nuorui Medicine Technology Co., Ltd. Registration number: 2011990000403 |
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Date of cancellation: 20121102 Granted publication date: 20091028 Pledgee: Beijing's first investment Company Limited by Guarantee Pledgor: Beijing Nuorui Medicine Technology Co., Ltd. Registration number: 2011990000403 |
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