CN100553700C - Be used for injecting automatically the equipment of activating agent - Google Patents
Be used for injecting automatically the equipment of activating agent Download PDFInfo
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- CN100553700C CN100553700C CN 200380103980 CN200380103980A CN100553700C CN 100553700 C CN100553700 C CN 100553700C CN 200380103980 CN200380103980 CN 200380103980 CN 200380103980 A CN200380103980 A CN 200380103980A CN 100553700 C CN100553700 C CN 100553700C
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- indicator
- equipment
- spring
- running part
- entry needle
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/206—With automatic needle insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3125—Details specific display means, e.g. to indicate dose setting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M2005/31518—Piston or piston-rod constructions, e.g. connection of piston with piston-rod designed to reduce the overall size of an injection device, e.g. using flexible or pivotally connected chain-like rod members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31566—Means improving security or handling thereof
- A61M5/3157—Means providing feedback signals when administration is completed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
- A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
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- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The present invention relates to be full of activating agent and have the syringe (50) of entry needle (37), described syringe can move in receiving unit (16) by the tension force of spring.Can pass second local path (55) that is used to thrust first local path (54) of entry needle (37) and is used to empty activating agent by the running part (5) that at least one spring (11) moves.Described at least one spring (11) acts between running part (5) and mid portion (10), and another spring (9) is at mid portion (10) and be fixedly connected to effect between the support section (8) of receiving unit (16).Be connected to mid portion (10) from the indicating device (12) of exterior visual.Only move during second local process and pass path (56) by the visual indicating device (12) of transparent part (51), this path (56) are substantially less than two partial stroke sums.
Description
Technical field
The application relates to the equipment that is used for injecting automatically reagent, this equipment has the container that is used for reagent, this container is movably located in the shell to be used to insert this entry needle together with the entry needle that is connected to the latter, this equipment also comprises syringe piston, and this syringe piston is movably located in the described container to be used to inject reagent.
Background technology
The equipment of the above-mentioned type, promptly so-called automatic injector has multiple known form.Especially, they are used to use the medicine of problematic patient oneself injection.So far failing a difficult problem of this automatic injector that solved satisfactorily is such fact, that is, after patient oneself began to insert injection needle, he did not also know how long and when to have continued injecting of medicine he can extract entry needle once more.A kind of possible solution to this difficult problem is that an indicator elment from exterior visual is connected to syringe piston.Yet because syringe piston has covered and inserts the required distance of entry needle before injecting medicine, therefore being directly connected to the indicator elment of syringe piston may be apt to be misleading and/or may increase the structure length of automatic injector undesirably.
Summary of the invention
Therefore task of the present invention is the equipment that proposes the described type of a kind of preface part, in this equipment, can determine it clearly from the outside when injection process finishes, and this equipment can not produce appreciable impact to the structure length of automatic injector.
According to the present invention, realize this task by such fact, that is, shorter than syringe piston with respect to total displacement of shell from the mobile route of the indicator of exterior visual.Syringe piston is to the degree of freedom of structural design that reduces to have increased indicator of the transmission path of indicator, and this is because the path of syringe piston is not directly depended in the path that indicator is passed.
According to one embodiment of present invention, the equipment that is used for injecting automatically reagent has the container that is used for reagent, this container and the entry needle that is attached thereto are movably located in the shell together to be used to insert this entry needle, this equipment also has syringe piston, this syringe piston is movably located in the described container to be used to inject reagent, wherein, shorter with respect to total displacement of shell from the mobile route of the indicator of exterior visual than syringe piston; Wherein, having can be by the running part of at least one spring element to move with described syringe piston, this running part can realize being used to insert first local path and second local path that is used to inject reagent of entry needle, thereby described at least one spring element is effectively at described running part be fixedly connected between the support section of shell, and the position of indicator between described spring element two ends is connected to described spring element.This embodiment has realized task of the present invention with simple especially structure and expensive benefit.
According to further embodiment of the present invention, the equipment that is used for injecting automatically reagent has the container that is used for reagent, this container and the entry needle that is attached thereto are movably located in the shell together to be used to insert this entry needle, this equipment also has syringe piston, this syringe piston is movably located in the described container to be used to inject reagent, wherein, shorter with respect to total displacement of shell from the mobile route of the indicator of exterior visual than syringe piston; Wherein, having can be by the running part of at least one spring element to move with described syringe piston, this running part can realize being used to insert first local path and second local path that is used to inject reagent of entry needle, described at least one spring element is effectively between described running part and mid portion, at least one additional springs element is effectively at described mid portion be fixedly connected between the support section of shell, and indicator is connected to described mid portion.Connecting of centre position by at least two spring elements and mid portion, can by reality freely mode design the path of indicator, thereby, for example can construct automatic injector, in this automatic injector, can use different syringes, especially the syringe that has different capabilities, thereby in this automatic injector, the path of the syringe piston that the drug dose in the bolus infusion device is required also can be changed.
Further embodiment according to the present invention provides a kind of lid, described blanketing lid indicator when described running part is realized first local path.By this mechanism, indicator is only visual after injecting beginning, and the user can observe bolus infusion processes and can not be instructed to the mobile of device during entry needle insertion and distract.
According to further specific embodiment of the present invention, the stress that retainer limits described additional springs reaches maximum spring force, and the size of described spring be configured such that described tensioning additional springs maximum spring force corresponding to after entry needle inserts with inject reagent before described to the instantaneous spring force that goes on foot a spring.Owing to this reason, described mid portion only during described second local path, promptly only moves during injecting reagent.Described retainer also can be owing to described additional springs is to be compressed to its compression spring that blocks length (Block length) to be implemented.
Additional stops is provided according to another embodiment of the invention, and this retainer limits the lax of described additional springs, thus the path that fixing described indicator covers.Realized that thus described indicator moves along the limited range that the length with described second path has nothing to do.This makes the use of the container with different capabilities become possibility.
According to a preferred embodiment of the present invention, described indicator forms ring-type.Therefore in any direction can see described indicator, thereby before the user is placed into injection position with the latter, not need to pay close attention to the position of rotation of this equipment around this equipment.
According to further embodiment of the present invention, described at least one spring and described additional springs coaxial arrangement, and at least at tensioning state, in them one telescopically is arranged in another to small part.This can make the design conserve space of this equipment and guarantee that especially this equipment can not become the length of difficult operation owing to the spring in conjunction with described indicator.
In another embodiment of the present invention, the equipment that is used for injecting automatically reagent has the container that is used for reagent, this container and the entry needle that is attached thereto are movably located in the shell together to be used to insert this entry needle, this equipment also has syringe piston, this syringe piston is movably located in the described container to be used to inject reagent, wherein, shorter with respect to total displacement of shell from the mobile route of the indicator of exterior visual than syringe piston; Wherein, having can be by the running part of at least one spring element to move with described syringe piston, this running part can realize being used to insert first local path and second local path that is used to inject reagent of entry needle, thereby indicator is connected to mid portion, this mid portion is connected at least one rolling element again, this rolling element described running part between moving period at described running part be fixedly connected between the zone of shell and roll.Described one or more rolling element passes half of path that described driving section branch passes.Can realize this solution simply.The slip of not expecting for fear of described at least one rolling element, the further embodiment of the present invention according to the present invention, have tooth on the periphery of this rolling element, the engagement of this tooth is arranged on the described running part and is fixedly attached to a plurality of teeth on the described zone of shell.
In another embodiment of the present invention, described indicator is positioned at the back-end region of this equipment, that is, and and the end that described entry needle is relative.This layout provides the comfortable operation of good visual and this equipment, and this device is held with one by the user usually during operation.In this case, give prominence to from user's handle the described rear end that has described indicator.
According to further embodiment of the present invention, when by transparent or semitransparent part during from the described indicator of exterior visual, can realize the closure designs of this equipment, particularly not have the design of slit or analog, thereby can meet typical strict hygienic requirements in this area.
Description of drawings
Below, discussed exemplary embodiments of the present invention with reference to the accompanying drawings by way of example in more detail, in the accompanying drawings:
Fig. 1 has shown the longitudinal profile of an embodiment of the automatic injector of the present invention under loading condition;
Fig. 2 has shown the longitudinal profile of the automatic injector under the unlocked state, and the relative Fig. 1 of this section has rotated 90 °.
Fig. 3 has shown the longitudinal profile that inserts entry needle automatic injector afterwards, and this section obtains by the plane identical with Fig. 2;
Fig. 4 has shown the longitudinal profile of injecting medicine automatic injector afterwards, and this section obtains by the plane identical with Fig. 2 and Fig. 3;
Fig. 5 has shown the longitudinal profile of the automatic injector after the withdrawal entry needle, and this section obtains by the plane identical with Fig. 1;
Fig. 6 A-6C has shown first embodiment of indicator;
Fig. 7 A-7C has shown second embodiment of indicator, and it is attached among the embodiment of automatic injector of Fig. 1-5 shown type;
Fig. 8 A-8C has shown the 3rd embodiment of indicator, and it is as first and second embodiment operation that has spring mechanism;
Fig. 9 A-9C has shown the 4th embodiment of indicator; And
Figure 10 A-10C has shown the 5th embodiment of indicator.
The specific embodiment
Automatic injector is made up of two critical pieces, i.e. container part shown in the left side in the drawings, and it holds the syringe of filling and the power unit shown in the right in the drawings, and the part that is used for inserting automatically and emptying syringe wherein has been installed.These two critical pieces are by admitting the pluging connector between sleeve pipe 16 and the power sleeve pipe 1 removably interconnection.In the following description, a side of the automatic injector at entry needle place is represented the place ahead.
By means of Fig. 1 of the automatic injector that shows operational ready, power unit is described at first now.The part that is used for driving automatic injector is contained in and grips sleeve pipe 14, grips telescopic rear end at this and has connected indicator window 51.Indicator window 51 is by transparent or semitransparent material manufacture or have opening, for example with the form of slit, thereby allows to be movably received within indicator 12 the indicator window 51 from visual observation.Indicator 12 has annular design, therefore can be in sight from any direction around automatic injector.Start 13 rear ends that are arranged in automatic injector, this startups is provided with covering disk 15 in face side thereafter.Power sleeve pipe 1 is contained in and grips in the sleeve pipe 14.In its back-end, power sleeve pipe 1 relies on to be connected and is connected to stop sleeve pipe 8.Part stop sleeve pipe 8 portion within it accommodates pogo barrel 10 movably.Pogo barrel 10 is connected to indicator 12 in the rear end by being connected.In the front side of pogo barrel 10, running part 5 is supported in the power sleeve pipe 1 movably.The task of running part 5 is to start the piston rod 52 of syringe 50 so that the material in the bolus infusion device, and this will specifically describe subsequently.Spring 9 is contained under tensioning state in the pogo barrel 10, and the front end of this spring is relying on pogo barrel 10 and rear end to abut against stop sleeve pipe 8.Second spring 11 that similarly is in tensioning state is positioned on the outside of pogo barrel 10, and front end is relying on running part 5 and the rear end abuts against pogo barrel 10.
The part that will be called as rotation restricting device for compressor piston 4 is positioned to use its front end, that is, the cannula-like end is against the axle collar of syringe, and this rotation restricting device for compressor piston runs through running part 5, and pogo barrel 10 and stop sleeve pipe 8 enter into and start a zone of 13.To front prestress, the rear end of described spring 7 is resisted against on the stop sleeve pipe 8 by 7 pairs of rotation restricting device for compressor piston 4 of spring.In its back-end, rotation restricting device for compressor piston 4 is kept in the position shown in the figure 1 by two locking plates 31 that are formed on the stop sleeve pipe 8, and described locking plate meshes the groove 32 on the rear end that is formed at rotation restricting device for compressor piston 4.Be contained in the radial opening 33 of rotation restricting device for compressor piston 4 such as spherical 6 stopping element and the recess 34 in the engaged transmission part 5, described retainer guarantees only can move jointly at this operating position running part 5 and rotation restricting device for compressor piston 4.Should be appreciated that to substitute spherical 6, other stopping element such such as pin also can be used.
Carry out the description of container part below.As described, the part that is used for holding syringe 50 is installed in admits sleeve pipe 16, and as described, this admittance sleeve pipe can be connected to power sleeve pipe 1.Along with the insertion of needle holder 22, sliding sleeve 21 self is admitted syringe.Under the situation that the road strategic point is slidingly connected, needle holder 22 has guaranteed that entry needle 37 just can not break away from syringe as long as the latter is arranged in automatic injector.At front end, needle holder 22 is resisted against on the support ring 24 that is connected to sliding sleeve 21.Have under the situation that road strategic point locking connects at syringe and needle set, entry needle is therefore by being threaded onto syringe, and do not use needle holder 22.Sliding sleeve 21 is movably located on and receives in the sleeve pipe 16, and is pressed into operating position shown in Figure 1 by spring 20.Cannula-like pin protector 17 is movably located on and receives in the sleeve pipe 16.These pin protector 17 front ends are by buckle closure 23 sealings, and this buckle closure has stayed the passage that is used for entry needle, and its rear end has inside flange 35.Spring 18 front ends are resisted against on the buckle closure 23 and the rear end is resisted against on the packing ring 19, and this packing ring remains on again on the support ring 24.In the figure, spring 18 is in its relaxed state.
In order to prepare injection, automatic injector must enter unlocked state shown in Figure 2 from guard mode shown in Figure 1.For this purpose, start 13 motion backward.This can take place because of following operation: hands is held this equipment receiving on the sleeve pipe 16, and another is held and started on 13, and spurs this two parts away from each other.By starting a particular design and a layout of 13, also can hold automatic injector and promote startup 13 backward gripping sleeve pipe 14 places with the thumb of same hand.Be located at a circumferential rib that starts on 13 and prevent thumb slippage in this case.With start 13 promote to be called release campaign in describing below backward.In this process, be not capped in the zone that starts a leading edge indicator window 41 of 13, be visible in this regional inside by painted boldly warning sleeve pipe 53, described warning sleeve pipe is clearly indicated the present non-locking of automatic injector and is prepared injection.In the release campaign, be formed on the locking plate 31 on the stop sleeve pipe and sliding starting the tongue 36 that inwardly forms on 13 the covering disk 15.Described tongue and locking plate form like this, make when tongue 36 between release moving period slides, flexibly to discharge that described locking plate 31 is fixed on the appropriate location by meshing above-mentioned groove 32 with rotation restricting device for compressor piston 4 in radial direction on locking plate 31.After the release, be formed at tongue 36 on the covering disk 15 with the form of wedge between locking plate 31.Along with the release campaign, thereby will start an initial position that is pressed into Fig. 1 in the spring 3 beginning tensionings that are formed at the hook on the stop sleeve pipe 8 and are fixed on effect between the retaining part 60 that starts on the head by being connected, guarantee that thus tongue 36 is resisted against on the locking plate 31 with slight prestressing force.Automatic injector is unripe to be used for injection and to be placed on patient skin, and buckle closure 23 is positioned at the position of expectation.In this case, the patient holds automatic injector at gripping sleeve pipe 14 places.The triggering of injection now only needs forward, promptly moves towards the direction of patient body to start 13.
Trigger in the motion at this, tongue 36 pushes between locking plate 31, and makes these locking plates separately diametrically, and rotation restricting device for compressor piston 4 is released thus, and pushes ahead by the power of spring 7.The power of spring 11 also helps to insert motion, and this masterpiece is used for running part 5.Because running part 5 is connected to rotation restricting device for compressor piston 4 by spherical 6, so the higher starting force of spring 11 joins in the power of spring 7 and helps entry needle advanced to reliably and thrusts the degree of depth fully.The power of the spring also cannula-like front end by rotation restricting device for compressor piston 4 is delivered on the axle collar of syringe 50 and promotes the latter forward, and syringe is contained in wherein sliding sleeve 21, thereby entry needle 37 advances and thrusts patient skin.In this motion, sliding sleeve 21 compresses springs 20 and compresses springs 18 by packing ring 19.Insert on the internal frame 41 that the shoulder 40 of path by rotation restricting device for compressor piston 4 be resisted against power sleeve pipe 1 and be limited.In this final position, the opening 33 that receives in spherical 6 the rotation restricting device for compressor piston 4 is aimed at the recess 42 in being located at power sleeve pipe 1, and spherical 6 can be discharged into the outside, and the connection between rotation restricting device for compressor piston 4 and the running part 5 is cancelled.Simultaneously, rotation restricting device for compressor piston 4 is close together with power sleeve pipe 1 lock now, thereby the power of spring 20 is received by the power sleeve pipe, therefore can not offset the power of the spring of injecting 7 of realization medicine.Therefore, start injection automatically now, the piston rod 52 of syringe is further moved forward by running part 5 under the power of spring 11 and 9.The size of spring 11 is configured to more much bigger than spring 9, to such an extent as to the moment pogo barrel 10 to the injection beginning still remains on position shown in Figure 3 with the indicator 12 that is connected to the latter, in this position, retainer is formed between the outwards outstanding flange and pogo barrel 10 of sleeve pipe 8.At this constantly, running part 5 has passed the path shown in 54 among Fig. 3.When inserting motion, spring 18 beginnings are by packing ring 19 tensionings, and described packing ring 19 is moved to the left by sliding sleeve 21 in the drawings.
When inserting entry needle 37, increase along with the path of running part 5, the power of spring is reduced to such degree, make just to arrive the moment that its final positions and entry needle 37 insert fully at rotation restricting device for compressor piston 4, spring 9 can make pogo barrel 10 leave its retainer towards stop sleeve pipe 8.Spherical 6 discharges running part 5 now, makes the latter slide in the rotation restricting device for compressor piston 4, and can start the piston rod 52 of syringe in this process.Spring 9 begins expansion now.Spring 9 promotes pogo barrel 10 forward, this pogo barrel 10 has indicator 12, therefore after passing through path 56, just also advance fully in syringe 50 and therefore moment of being injected of all fluids in the syringe when piston rod 52, indicator 12 arrives visible final position among its Fig. 4.As a result, under the help of indicator 12, the user can follow the tracks of injection process and see the whole inclusions that syringe is injected in position shown in Figure 4.In this case, the path 56 of indicator 12 and the path independence of the piston rod 52 of syringe 50, and the path 54+55 than running part 5 is short basically.By these mechanisms, avoided the unnecessary length of automatic injector on the one hand, the syringe that has different displacements on the other hand can be used for this automatic injector.The attendant advantages that this design has is that the higher starting force of spring 11 is used for insertion process, and therefore this process carries out as required more slowly.
Fig. 6 A-6C shows a possibility embodiment of indicator.Although the embodiment that this is simple in structure does not also correspond to the indicator that is included in the above-mentioned automatic injector, the part with identical function has identical Reference numeral.Only difference is mid portion, and this mid portion forms pogo barrel 10 in the embodiment of Fig. 1-5, and in Fig. 6 A-6C with reference number 10 ' represent.Fig. 6 A has shown the relative position between the each several part that is presented in the automatic injector of the tensioning of preparing injection.From this position, running part 5 is moved to the left, and it is described with reference to figure 1-5.Further aforesaid stop sleeve pipe 8 is fixedly connected to and grips sleeve pipe 14, keeps its position in Fig. 6 A-6C.Two shown springs, promptly stop sleeve pipe 8 and mid portion 10 ' between effect spring and mid portion 10 ' and running part 5 between the spring 11 of effect in the position tensioning shown in Fig. 6 A.Fig. 6 B has shown the position of the part of the entry needle 37 that has insertion.Running part 5 moves sliding sleeve 21 together with syringe 50, and moves forward by path 54 in this process.Simultaneously, mid portion 10 ' move a certain distance pari passu together with indicator 12, less than the distance in path 54, we can easily realize from Fig. 6 B this distance basically.During injecting medicine, wherein running part 5 further is moved to the left the final position that arrives Fig. 6 C up to it by path 55, pogo barrel 10, and and its indicator 12 together, similarly be moved further by path 59 pro rata with running part 5.Therefore the path 59 of indicator 12 has shown the progress that medicine is injected, and this path is to user's particular importance.Recall the final position of automatic injector if the patient waits for, can prevent the partial loss of medicine so up to indicator arrival Fig. 6 C.If someone wishes to prevent during inserting to see the path that indicator is passed from the outside, this people can use and cover 61 so, and it only opens demonstration on indicator 12 after injecting beginning.
Fig. 7 A-7C shows second embodiment of indicator, for example is combined among the embodiment with reference to the described automatic injector of figure 1-5.The position of running part is identical with Fig. 6 A-6C of front,, is in the preparation inject state of tensioning in Fig. 7 A that is, and entry needle is inserted in Fig. 7 B, is injected at Fig. 7 C Chinese medicine.Compare with the embodiment of Fig. 6 A-6C, here spring 9 and 11 parts are telescopically overlapping.Pogo barrel 10 makes it to become possibility, this pogo barrel extend in the spring 11 and within it portion hold spring 9.The advantage that this design produces is that the total length of automatic injector can be shorter than the situation end in aforementioned indicator structure.In addition, the prior characteristics of this design are that pogo barrel 10 only inserts and bolus infusion processes just begins to move when beginning when entry needle together with indicator 12.This realizes according to following method: identical with the situation of previous embodiment, here spring 9 and 11 also is connected in series basically.Yet, because the elastic force of spring 9 is restricted, and since pogo barrel 10 be resisted against on the stop sleeve pipe 8 at right-hand member, therefore in the power of the initial position spring 11 of Fig. 7 A power greater than spring 9.From this position, the power of spring 11 descends along with passing path 54, but temporary transient still greater than the power of the spring 9 of tensioning.In the position of Fig. 7 B, the power of spring 11 arrives the level of the power that just in time equals spring 9.From here on, during injecting medicine, wherein running part 5 further is moved to the left the final position (corresponding to Figure 4 and 5) that arrives Fig. 7 C up to it, pogo barrel 10 by path 55, and and its indicator 12 together, move by path 56 pro rata with running part 5.
Fig. 8 A-8C shows the 3rd embodiment of indicator.This embodiment is very similar to the embodiment shown in Fig. 6 A-6C, and it has still shown a kind of more simple proposal.Replace spring 9 and 11, only arranged one spring 58 here.Under this simplest situation, indicator 12 can be made up of the labelling on spring 58 peripheries, and described labelling for example can be applied in the longitudinal center of spring.Yet preferably, indicator 12 is the annulus that are connected to spring 58 in this embodiment.What here be used for indicator is connected to spring also is mid portion, " expression that this mid portion is with 10 in this embodiment.Mid portion 10 " can be connected to spring 58 with different modes.For example, mid portion 10 " can be cyclic, be promoted by spring 58, and for example arrive the latter by bonding connection.Another kind of connection possibility is to form mid portion with annular form, and its inside dimension is set makes its external diameter less than spring 58.Like this, spring 58 can be screwed into mid portion 10 " in.Like this, spring 58 can be screwed into mid portion 10 " in.Around the plastic material of at last, mid portion 10 " can be formed and be connected to spring 58 with the injection moulding form by plastics, the part of spring 58 be injected into mid portion 10 thus ".The path that the independent sector of this embodiment passes is identical with the embodiment of Fig. 6 A-6C, same reference numerals is used for the path of Fig. 8 A-8C owing to this reason.
Fig. 9 A-9C shows the 4th embodiment of indicator.Compare with the above embodiments, the 4th embodiment is not based on rolling element based on spring, and this will make an explanation below.Causing the element of indicator motion in this example still is piston 5.The latter's a part is schematically illustrated among the figure and be denoted as 5 '.For simplicity, not shown spring in Fig. 9 A-9C.Yet identical with the above embodiments, the motion that is used to insert pin and inject the piston 5 of reagent relies on spring force equally.Near this part 5 ' be the mid portion of another kind of form, in this example, be denoted as 10 " '.This mid portion 10 " ' vertically movably in piston 5 ' and the extension 1 of power sleeve pipe 1 ' or be fixedly connected between the latter's the part and extend.As shown in the figure, indicator 12 in this example ' be positioned at equally mid portion 10 " ' on, described indicator can be used as discrete component and is connected to mid portion 10 " '.Mid portion 10 " ' the entire path 56 that can pass limits in the following manner: left end by indicator 12 ' be resisted against power sleeve pipe 1 ' on, part 8 that right-hand member is connected to stop sleeve pipe 8 by indicator 12 ' be resisted against ' on.Lid 61 ' can be used as discrete component to be connected to last described part.Many recesses 67 are combined in mid portion 10 " ' in, rolling element 62 is arranged in the described recess.Piston 5 during inserting ' when being moved to the left in the drawings, rolling element 62 power sleeve pipe 1 ' and piston 5 ' between roll, and in this process, passed half of path that piston 5 passed.In this case, rolling element 62 is by part 10 between the cornice disorder of internal organs of recess 67 " ', also therefore drive certainly indicator 12 '.Rolling element 62 can form spherical or the short column body.Preferably, the three interval angles that are oriented to 120 ° of row's rolling elements 62 are distributed on the circumference of automatic injector.
The shortcoming of the last described embodiment of indicator be especially rolling element 62 and adjacent part 1 ' with 5 ' friction be connected.Figure 10 A-10C shows the 5th embodiment of indicator, and this indicator does not have this shortcoming.Here, guaranteed at piston 5 ' drive mid portion 10 " ' in interlocking, the indicator among this embodiment can not slided thus.This interlocking realizes by at least one gear 63, this gear rotationally in axle 64 upper supports at mid portion 10 " ' recess 67 in.63 engagements of this gear be arranged in power sleeve pipe 1 ' on tooth and be arranged in piston 5 ' on tooth 66.Piston 5 ' moving period between, gear 63 is driven and is not slided, and partly drives mid portion 10 by axle 64 " '.Advantageously, two or three gear 63 distributed earths are arranged on the automatic injector ground circumference.
When inserting the motion beginning, outwards outstanding by the flexible tongue 38 that the inwardly outstanding step cutting pattern 39 that receives sleeve pipe 16 prevents to be located in the sliding sleeve 21.When inserting the motion end, we can see from Fig. 5 that this flexibility tongue is outstanding from the outer surface of sliding sleeve 21.When indicator 12 indication medicines were injected fully, the user can recall automatic injector.The spring 18 of prestress during the insertion process guaranteed during automatic injector is recalled pin protector 17 still with patient's contact skin.Therefore pin protector 17 moves forward up to covering entry needle 37 fully with respect to receiving sleeve pipe 16.Flexible tongue 38 breaks away from fast in flange 35 back of pin protector 17 and guarantees that the latter can not be pushed to get back to and receives in the sleeve pipe 16.By these mechanisms, avoided the danger of any entry needle injury.
Claims (11)
1. be used for injecting automatically the equipment of reagent, it has the container (50) that is used for reagent, this container and the entry needle (37) that is attached thereto are movably located in the shell (16) together to be used to insert this entry needle (37), this equipment also has syringe piston (52), this syringe piston is movably located in the described container (50) to be used to inject reagent, wherein, shorter with respect to total displacement of shell (16) from the mobile route of the indicator (12) of exterior visual than syringe piston (52);
Wherein, having can be by the running part (5) of at least one spring element (11) to move with described syringe piston (52), this running part can be realized second local path (55) that is used to insert first local path (54) of entry needle (37) and is used to inject reagent, described at least one spring element (11) is positioned at described running part (5) effectively and is fixedly connected between the support section (8) of shell (16), and the position of indicator (12) between described spring element (11) two ends is connected to described spring element (11).
2. be used for injecting automatically the equipment of reagent, it has the container (50) that is used for reagent, this container and the entry needle (37) that is attached thereto are movably located in the shell (16) together to be used to insert this entry needle (37), this equipment also has syringe piston (52), this syringe piston is movably located in the described container (50) to be used to inject reagent, wherein, shorter with respect to total displacement of shell (16) from the mobile route of the indicator (12) of exterior visual than syringe piston (52);
Wherein, having can be by the running part (5) of at least one spring element (11) to move with described syringe piston (52), this running part can be realized second local path (55) that is used to insert first local path (54) of entry needle (37) and is used to inject reagent, and described at least one spring element (11) is positioned at described running part (5) and mid portion (10 effectively; 10 ') between, at least one additional springs element (9) is positioned at described mid portion (10 effectively; 10 ') and be fixedly connected between the support section (8) of shell (16), this indicator is connected to described mid portion (10; 10 ').
3. according to the equipment of claim 2, it is characterized in that: the stress that retainer limits described additional springs (9) reaches maximum spring force, and the size of described spring (9,11) be configured such that described tensioning additional springs (9) maximum spring force corresponding to after entry needle inserts with inject reagent before the instantaneous spring force of described at least one spring (11).
4. according to the equipment of claim 3, it is characterized in that: additional stops limits the lax of described additional springs (9), thereby limits the path that described indicator (12) is passed.
5. according to the equipment of one of claim 2-4, it is characterized in that: described at least one spring (11) and described additional springs (9) coaxial arrangement, and at least at tensioning state, in them one telescopically is arranged in another to small part.
6. be used for injecting automatically the equipment of reagent, it has the container (50) that is used for reagent, this container and the entry needle (37) that is attached thereto are movably located in the shell (16) together to be used to insert this entry needle (37), this equipment also has syringe piston (52), this syringe piston is movably located in the described container (50) to be used to inject reagent, wherein, shorter with respect to total displacement of shell (16) from the mobile route of the indicator (12) of exterior visual than syringe piston (52);
Wherein, having can be by the running part (5 ') of at least one spring element (11) to move with described syringe piston (52), this running part can be realized second local path (55) that is used to insert first local path (54) of entry needle (37) and is used to inject reagent, indicator (12) is connected to mid portion (10 " '), this mid portion be connected to again at least one rolling element (62; 63), at described running part (5 ') between moving period, this rolling element is at described running part (5 ') and be fixedly connected between the zone (1 ') of shell (16) and roll.
7. according to the equipment of claim 6, it is characterized in that: described at least one rolling element (63) has tooth on its periphery, this tooth be arranged in described running part (5 ') and go up and be fixedly connected to a plurality of teeth (65,66) engagement on the described zone (1 ') of shell (16).
8. according to the equipment of one of claim 1-4, it is characterized in that: when running part (5) is realized first local path, cover indicator (12) by lid (61).
9. according to the equipment of one of claim 1-4, it is characterized in that: indicator (12) is a ring-type.
10. according to the equipment of one of claim 1-4, it is characterized in that: indicator (12) is positioned at the back-end region of this equipment, and this zone is opposite with described entry needle (37).
11. the equipment according to one of claim 1-4 is characterized in that: indicator (12) by transparent or semitransparent part (51) from exterior visual.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH01984/02A CH695926A5 (en) | 2002-11-25 | 2002-11-25 | Device for automatically injecting an active ingredient. |
| CH1984/02 | 2002-11-25 | ||
| CH837/03 | 2003-05-13 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1713929A CN1713929A (en) | 2005-12-28 |
| CN100553700C true CN100553700C (en) | 2009-10-28 |
Family
ID=32331826
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200380103980 Expired - Fee Related CN100553700C (en) | 2002-11-25 | 2003-11-17 | Be used for injecting automatically the equipment of activating agent |
Country Status (4)
| Country | Link |
|---|---|
| CN (1) | CN100553700C (en) |
| AU (1) | AU2003280269A1 (en) |
| CH (1) | CH695926A5 (en) |
| WO (1) | WO2004047891A1 (en) |
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| CN103747824A (en) * | 2011-08-24 | 2014-04-23 | 尤尼特拉克特注射器公司 | Auto-injector for retractable prefilled syringe |
| US9750885B2 (en) | 2013-05-01 | 2017-09-05 | Unl Holdings Llc | Plunger-driven auto-injectors |
| US10046115B2 (en) | 2012-07-05 | 2018-08-14 | Unl Holdings Llc | Drive control mechanisms and automatic injectors for injectable cartridges |
| US10300201B2 (en) | 2012-02-06 | 2019-05-28 | Unl Holdings Llc | Plunger sub-assemblies and auto-injectors having low retraction activation force |
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| GB2414404B (en) | 2004-05-28 | 2009-06-03 | Cilag Ag Int | Injection device |
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| GB2414399B (en) | 2004-05-28 | 2008-12-31 | Cilag Ag Int | Injection device |
| GB2414775B (en) | 2004-05-28 | 2008-05-21 | Cilag Ag Int | Releasable coupling and injection device |
| GB2414400B (en) | 2004-05-28 | 2009-01-14 | Cilag Ag Int | Injection device |
| GB2414409B (en) | 2004-05-28 | 2009-11-18 | Cilag Ag Int | Injection device |
| GB2414405B (en) | 2004-05-28 | 2009-01-14 | Cilag Ag Int | Injection device |
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| WO2006057636A1 (en) | 2004-11-22 | 2006-06-01 | Intelliject, Llc | Devices, systems, and methods for medicament delivery |
| US11590286B2 (en) | 2004-11-22 | 2023-02-28 | Kaleo, Inc. | Devices, systems and methods for medicament delivery |
| US10737028B2 (en) | 2004-11-22 | 2020-08-11 | Kaleo, Inc. | Devices, systems and methods for medicament delivery |
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| WO2009040605A1 (en) * | 2007-09-25 | 2009-04-02 | Becton Dickinson France | Autoinjector with trigger positionable in active position by movement of a safety shield and indication of the active position |
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| EP2583704A1 (en) * | 2011-10-21 | 2013-04-24 | Sanofi-Aventis Deutschland GmbH | Autoinjector |
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- 2002-11-25 CH CH01984/02A patent/CH695926A5/en not_active IP Right Cessation
-
2003
- 2003-11-17 WO PCT/CH2003/000754 patent/WO2004047891A1/en not_active Application Discontinuation
- 2003-11-17 CN CN 200380103980 patent/CN100553700C/en not_active Expired - Fee Related
- 2003-11-17 AU AU2003280269A patent/AU2003280269A1/en not_active Abandoned
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103747824A (en) * | 2011-08-24 | 2014-04-23 | 尤尼特拉克特注射器公司 | Auto-injector for retractable prefilled syringe |
| CN103747824B (en) * | 2011-08-24 | 2016-08-17 | 尤尼特拉克特注射器控股有限公司 | Automatic injector for concertina type precharging type syringe |
| TWI608853B (en) * | 2011-08-24 | 2017-12-21 | 尤尼特拉克特注射器控股有限公司 | Auto-injector for retractable prefilled syringe and method of assembly1ng an automatic syringe |
| US10166336B2 (en) | 2011-08-24 | 2019-01-01 | Unl Holdings Llc | Auto-injector for retractable prefilled syringe |
| US10300201B2 (en) | 2012-02-06 | 2019-05-28 | Unl Holdings Llc | Plunger sub-assemblies and auto-injectors having low retraction activation force |
| US10046115B2 (en) | 2012-07-05 | 2018-08-14 | Unl Holdings Llc | Drive control mechanisms and automatic injectors for injectable cartridges |
| US10894128B2 (en) | 2012-07-05 | 2021-01-19 | Unl Holdings Llc | Drive control mechanisms and automatic injectors for injectable cartridges |
| US9750885B2 (en) | 2013-05-01 | 2017-09-05 | Unl Holdings Llc | Plunger-driven auto-injectors |
| US11033689B2 (en) | 2013-05-01 | 2021-06-15 | Unl Holdings Llc | Plunger-driven auto-injectors |
Also Published As
| Publication number | Publication date |
|---|---|
| CH695926A5 (en) | 2006-10-31 |
| AU2003280269A1 (en) | 2004-06-18 |
| CN1713929A (en) | 2005-12-28 |
| WO2004047891A1 (en) | 2004-06-10 |
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Granted publication date: 20091028 Termination date: 20101117 |