CN100522181C - Anoxia and fatigue-resisting health-care oxygen, its preparation and use as health-care product - Google Patents

Anoxia and fatigue-resisting health-care oxygen, its preparation and use as health-care product Download PDF

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CN100522181C
CN100522181C CNB2006100894936A CN200610089493A CN100522181C CN 100522181 C CN100522181 C CN 100522181C CN B2006100894936 A CNB2006100894936 A CN B2006100894936A CN 200610089493 A CN200610089493 A CN 200610089493A CN 100522181 C CN100522181 C CN 100522181C
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health
potassium
oxygen
sodium
care
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CN1895270A (en
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王锡麟
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Tibet sqyk investment Limited by Share Ltd
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Thindo Fang Technology Development (beijing) Co Ltd
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Abstract

A health-care oxygen product in the form of beverage, toothpaste mate, or medicine for treating constipation is proportionally prepared from sodium (or potassium) chlorite, sodium (or potassium) bicarbonate, sodium (or potassium) carbonate, and deionized water through preparing the aqueous solution of sodium (or potassium) bicarbonate and sodium (or potassium) carbonate, dissolving the sodium (or potassium) chlorite in it, and dripping it in purified water, cold boiled water, mineral water, or sugar solution. It can improve immunity, relieving fatigue, and treating anoxia.

Description

Health-care oxygen of anoxia and fatigue-resisting and preparation method thereof and as the application of health product
Technical field
The present invention relates to a kind of health-care oxygen and preparation method thereof of anoxia and fatigue-resisting and, belong to the functional health product technical field as the application of health product.
Background technology
Oxygen is self-evident for the importance of humans and animals, and it is one of basic biological element, is the key of life process.Traditional view thinks that respiratory system is the unique channel that obtains the oxygen supply, but for people at the highlands life and work, for respiratory system and the problematic people of blood circulation, for the athlete in the strenuous exercise and strong physical work person and spirit and the bigger people of body pressure, only rely on breathe air, the supply of oxygen is far from being enough, will produce " air hunger ", and then cause dizziness, altitude sickness, weak tired out, absent minded, amentia, asthma etc., for a long time " air hunger " can cause the when injected organism tissue oxidative metabolism, energy metabolism, substance metabolism reaches cellularity unusually and changes, finally cause immune system, gastrointestinal system, various discomforts and disease cause in blood circulation tissue injury.
Before more than 100 years, scientists wishes to make a kind of " drinkable oxygen " just at the technology and the product of research " oxygen therapy " or " oxygen benefit ", as replenishing the oxygenating of breathing channel.Initial product is the unstable oxygen of hydrogen peroxide one class, but it can bring radical damage to human body.Last century, the scientist of the 80-90 age U.S. took the lead in having invented stable oxygen (Stabilized Oxygen), activity stabilized oxygen products such as (ASO), and introduced to the market, and its manufacture method is kept absolutely secret, and discloses that effective ingredient is an Atlantic Ocean sea salt.Application number is that the Chinese patent application of CN200510048660.8 discloses a kind of " functional health-care food of anti-hypoxia and free radical resisting and preparation method thereof ", this is a kind of Chinese medicine preparation based on Radix Notoginseng, Radix Rhodiolae active component, and anti-hypoxia, free radical resisting effect are arranged.Application number is that 03117918.5 Chinese patent file discloses a kind of " production method and the device thereof that contain the liquid of active oxygen ", claim its product to have the effect of edible oxygenating, but wherein effective ingredient is O 3, content 3.1-11.6mg/L.The product that also has " heavy-oxygen-enriched water " " active oxygen " and so on the market is by the dissolved oxygen content in the method short time increase water of pressurization or bubbling mostly, is unsettled.China does not still have a kind of stability " oxygen tonic " of diatomic oxygen form of Gong drinking so far.
Summary of the invention
The objective of the invention is to propose a kind of health-care oxygen and preparation method thereof of anoxia and fatigue-resisting and as the application of health product, with the stability " oxygen tonic " that a kind of diatomic oxygen form of Gong drinking is provided.
The health-care oxygen of the anoxia and fatigue-resisting that the present invention proposes, wherein the percetage by weight of each composition is:
Sodium chlorite or potassium chlorite 2~10%
Sodium bicarbonate or potassium bicarbonate 2~10%
Sodium carbonate or potassium carbonate 0.2~5%
Deionized water 95~75%.
The preparation method of above-mentioned health-care oxygen comprises following each step:
(1) presses the aqueous solution that above-mentioned percentage by weight disposes sodium bicarbonate and sodium carbonate or potassium bicarbonate and potassium carbonate;
(2) by above-mentioned percentage by weight sodium chlorite or potassium chlorite are dissolved in the above-mentioned corresponding aqueous solution.
Above-mentioned health-care oxygen is as the application of health product, health product wherein be healthy and strong anti-fatigue health-product containing, human body oxygenating health product, enhancing immunity health product, the health product that purify the blood, purify any in intestines and stomach health-care product, the cleaning oral cavity health product.
The application of health-care oxygen of a kind of anoxia and fatigue-resisting that the present invention proposes and preparation method thereof and health product has following characteristics and advantage:
1, efficacy test:
Check belongs to nontoxic level through toxicology for drinkable health-care oxygen of the present invention, its product, does not have three zests of making peace, and meets the relevant requirements of China's food law.
In order to verify effect of the present invention, resisting fatigue, anti-hypoxia, anti-cerebral ischemia hypoxia test have been carried out with 150 SPF level ICR mices.Test is blank with the deionized water, with the positive contrast of Beijing royal jelly solution, feeds continuously after 30 days and carries out every test.
50 mices are placed the swimming with a load attached to the body of swimming case, the record time-to-live (table 1):
Table 1 anti-fatigue test
Group Dosage, mg/KgBW Number of animals, only The swimming with a load attached to the body time, divide
Dosage group small dose group positive control in the heavy dose of group of blank — 1 0.5 0.25 3.3 10 10 10 10 10 3.8±0.90 5.8±1.93* 5.9±1.31** 5.3±1.40 4.7±1.37
Annotate: with the contrast of blank group, * P ∠ 0.05**P ∠ 0.01
The mathematical statistics of data shows that the time of mice swimming with a load attached to the body, the person was the longest to take the health-care oxygen, and is remarkable with the matched group comparing difference, and the time-to-live is the longest to have prolonged 55%.
Place 50 port grinding bottles of obturaging until suffocating the instrumentation time-to-live (table 2) respectively 50 mices: the test of table 2 anti-hypoxia
Group Dosage, mg/KgBW Number of animals, only Time-to-live, divide
Dosage group small dose group positive control in the heavy dose of group of blank — 1 0.5 0.25 3.3 10 10 10 10 10 21.4±1.53 27.8±1.74*** 26.2±2.84*** 22.3±2.97 22.2±1.88
Annotate: with the contrast of blank group, * * * P ∠ 0.001
The mathematical statistics of data shows that the person is the longest to take the health-care oxygen by the vexed lethal time-to-live for mice, and with matched group comparing difference highly significant, the time-to-live is the longest to have prolonged 30%.
By only breaking end, instrumentation is dehisced the time of breathing (table 3) with 50 mices:
Table 4 anti-cerebral ischemia hypoxia test
Group Dosage, mg/KgBW Number of animals, only Breathe the time, second
Dosage group small dose group positive control in the heavy dose of group of blank — 1 0.5 0.25 3.3 10 10 10 10 10 14.0±0.90 17.1±1.33*** 18.2±1.07*** 18.6±0.61*** 17.7±2.18***
Annotate: with the contrast of blank group, * * * P ∠ 0.001
The mathematical statistics of data shows that decapitated mice is breathed, and the time, the person was the longest to take the health-care oxygen, and with matched group comparing difference highly significant, the time of breathing is the longest to have prolonged 33%.
Several aspiration trier feedacks show, health-care oxygen of the present invention for strengthen human body physical agility, improve sleep, alleviate gout pain, improve the epilepsy symptom, many-sides such as treatment colitis and constipation all have positive effect.The microexamination of patient's intravital blood is explanation intuitively also, takes health-care oxygen blood quality improving after 21 days, and the coherent erythrocyte of uniting is originally separated, the blood smooth smoothness that becomes.
2, provide the basic nutrition support to human body
Drinkable health-care oxygen of the present invention can be called " oxonium salt ", its main effective ingredient alkali metal chlorite NaClO from forming 2Or KClO 2, be a kind of very special electrolyte that contains the diatomic negative oxygen ion, chlorine wherein, sodium or potassium are the necessary nutritional labelings of human body, " O wherein 2" be different from the oxygen in the hydrogen peroxide, what the latter discharged is monatomic free radical oxygen " O ", also is different from the dissolved oxygen in the water, but a kind of combined state oxygen do not discharge under condition of storage, but in case enter the humans and animals human body, under the effect of some enzyme, O 2Promptly can discharge, can catch too much free radical H in the body +Improve acidic physique, eliminate radical damage, simultaneously can enter blood, play the raising blood oxygen saturation, purify the blood, reduce lactic acid accumulation in the body, strengthen the generation of adenosine triphosphate (ATP), the normal oxidative metabolism of sustenticular cell, energy metabolism, effects such as substance metabolism, thereby make the immune system of body, blood circulation, digestive system, respiratory system improves, so health-care oxygen of the present invention is not the medicine at certain disease, but a kind of basic nutrition backer that extra oxygen is provided to human body, be a kind of oxygen tonic, a kind of very useful health product.Table 4 has been listed the blood gas analysis result that a man takes ten minutes posterior vein blood samples of health-care oxygen:
Table 4 blood gas analysis
Time, divide oxygen saturation, % blood oxygen pressure, mmHg
0 33.7 21.8
10 47.5 26.8
20 55.6 31.5
30 59.2 32
40 67.6 35.3
50 74.4 41.3
60 82.8 48.7
70 88.4 55.4
80 82.5 45.7
90 78 40.8
100 76.2 44.2
110 73.4 42.1
120 51.8 29
130 35.5 21.3
3, of many uses
(1) is used to the resisting fatigue of being healthy and strong: as basic effective constituents, can be added on and make plateau beverage, sports drink in the multiple soft drink, be healthy and strong and recall beverage etc., be applicable to athlete, highlands work life tourism crowd, strong physical work person, soldier, the brute force person of requiring mental skill, the dull-witted cerebral hypoxia ischemia patient of epilepsy and weak crowd tired out worn with age.
(2) be used for oxygenating: as respiratory system being drawn replenishing of oxygen, improve sick symptoms such as asthma, emphysema, fistula imbalance, bronchitis, lung is weak, alleviate anoxybiotic untoward reaction.
(3) be used to strengthen immune function of human body: increase leukocyte, capture H +The effect of free radical, reinforcement superoxide dismutase and myeloperoxidase (MPO) reaches the effect of regulating strengthening immune system, helps multiple diseases such as preventing cold, influenza, cough.
(4) be used to improve blood of human body circulation: purify the blood, eliminate deposition, strengthen nutritional labeling and transmit, can improve the symptom of the various pain diseases that cause owing to thrombosis, mineral deposit and hypertension, diabetes.For staying in air-conditioning office for a long time and suffering the crowd of the ice-cold numbness of trick beneficial especially.
(5) be used for detoxifcation, elimination infection: can kill the pathogenic anaerobe of intestinal, protect aerobic probiotics, can clear up refuse in the body, purify gastrointestinal system, be used as the necessary component of medicine for enterogastritis and emplastic.Can use together with toothpaste when being used for oral cavity cleaning and as a kind of effective ingredient of collutory.
The specific embodiment
The health-care oxygen of the anoxia and fatigue-resisting that the present invention proposes, wherein the percetage by weight of each composition is:
Sodium chlorite or potassium chlorite 2~10%
Sodium bicarbonate or potassium bicarbonate 2~10%
Sodium carbonate or potassium carbonate 0.2~5%
Deionized water 95~75%.
The preparation method of above-mentioned health-care oxygen is at first to dispose the aqueous solution of sodium bicarbonate and sodium carbonate or potassium bicarbonate and potassium carbonate by above-mentioned percentage by weight; By above-mentioned percentage by weight sodium chlorite or potassium chlorite are dissolved in the above-mentioned corresponding aqueous solution then.
The application as health product of above-mentioned health-care oxygen, health product wherein be healthy and strong anti-fatigue health-product containing, human body oxygenating health product, enhancing immunity health product, the health product that purify the blood, purify any in intestines and stomach health-care product, the cleaning oral cavity health product.
Alkali metal chlorite used in the inventive method is an electrolyte oxygen, is main effective ingredient of the present invention.Handle through the above recrystallization of secondary with preceding, at 40 ℃ of following infrared dryings, to remove objectionable impurities.
Alkali carbonate and bicarbonate used in the inventive method are necessary components, form buffer system in aqueous solution, so that steady in a long-term the storage.The food grade materials that must use the SILVER REAGENT raw material or purify through recrystallization is to guarantee the edible safety of health product.
Health-care oxygen of the present invention can be added in the multiple soft drinks such as mineral water, pure water and make plateau beverage, sports drink, be healthy and strong and recall beverage etc., is used for athlete, highlands work life tourism crowd, strong physical work person, soldier, the brute force person of requiring mental skill, the dull-witted cerebral hypoxia ischemia patient of epilepsy and weak crowd tired out worn with age.
The health-care oxygen of the resisting fatigue anti-hypoxia that the present invention proposes, dropping is drunk every day in cold water or pure water, can pass through digestive system, extra to the body oxygenating, as replenishing to respiratory system, improve weak etc. the symptom of asthma, emphysema, fistula imbalance, bronchitis, lung, alleviate the anoxybiotic untoward reaction of human body.Application aspect the enhance immunity systemic-function can be regulated and strengthening immune system, helps multiple diseases such as preventing cold, influenza.In the application that improves aspect the blood quality, can purify the blood, eliminate deposition, strengthen nutritional labeling and transmit, improve because the symptom of various pain diseases that thrombosis, mineral deposit cause and hypertension, diabetes.For staying in air-conditioning office for a long time and suffering the crowd of the ice-cold numbness of trick beneficial especially.Application aspect detoxifcation, elimination infection; can be used as a kind of noresidue does not have the full effect antibiotic of Drug resistance, kills the pathogenic anaerobe of intestinal, protects aerobic probiotics, refuse in the cleaning body; purify gastrointestinal system, can be as treating constipation medicine and the intestines and stomach the effective elements of the medicine.Application aspect elimination halitosis, prevention gingiva can be used as a kind of antozostomatic and sterilizing oral agent, can use and make collutory together with toothpaste.
Each component in the health-care oxygen of above-mentioned anoxia and fatigue-resisting is the component that is necessary, is containing on the basis of said components, can add or not add as operable other trace element of health product and nutrient, to reach different health care purposes.
Below be embodiments of the invention:
Embodiment 1
With 80 gram content is that 85% industrial sodium chlorite is through three recrystallization, dry down with infrared ray at 40 ℃, can obtain the pure sodium chlorite of about 67 grams, it is dissolved in 1 liter of buffer solution of being made up of about 6% analytical pure sodium bicarbonate and 0.25% analytical pure sodium carbonate, can obtains 1 liter of oxygen content (O 2The drinkable health-care oxygen health care liquid of) 〉=15000mg/L.Colourless, tasteless, outward appearance is the same with pure water.According to being healthy and strong or other needs, dropping 10-50 drips in 150 milliliters of cold water and drinks every day 1-3 time.After common 3 weeks to 3 month, can receive resisting fatigue, anti-hypoxia, enhancing immunity, the effect that purifies the blood.
Embodiment 2
With 40 gram content is that 85% industrial potassium chlorite is through three recrystallization, dry down with infrared ray at 40 ℃, can obtain the pure potassium chlorite of about 33.5 grams, it is dissolved in 1 liter of buffer solution of being made up of about 3% analytical pure potassium bicarbonate and 1.5% analytical pure potassium carbonate, can obtains 1 liter of oxygen content (O 2The drinkable health-care oxygen health care liquid of) 〉=9000mg/L.According to being healthy and strong or other needs, drip 20-100 and drip health-care oxygen solution in one bottle of 300 milliliters of mineral water, every day, the 2-3 bottle was drunk several times.
Embodiment 3
The health-care oxygen solution of making among the embodiment 1 is dripped 3 on toothbrush, brush teeth every day with toothpaste, can antihalitosis and elimination gingival infection.
Embodiment 4
With 20 of the health-care oxygen solution made among the embodiment 1, join in 150 milliliters of cold water, to take every day 1~2 time, the constipation situation promptly can improve the same day.
Embodiment 5
In the health-care oxygen solution of making in embodiment 1, press the concentration of 0.2g/L and add potassium chloride, redilution is drunk, and can give the human body kalium replenishment.

Claims (1)

1, a kind of preparation method of health-care oxygen of anoxia and fatigue-resisting is characterized in that this method comprises following each step:
(1) dispose sodium bicarbonate and sodium carbonate by weight percentage, or the aqueous solution of potassium bicarbonate and potassium carbonate;
(2) by weight percentage sodium chlorite is dissolved in the aqueous solution of above-mentioned sodium bicarbonate and sodium carbonate, or potassium chlorite is dissolved in the aqueous solution of above-mentioned potassium bicarbonate and potassium carbonate,
Percentage by weight wherein is:
Sodium chlorite or potassium chlorite 2~10%
SILVER REAGENT or the food stage sodium bicarbonate or the potassium bicarbonate 2~10% that purify through recrystallization again
SILVER REAGENT or the food stage sodium carbonate or the potassium carbonate 0.2~5% that purify through recrystallization again
Deionized water 95~75%.
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CN109010363A (en) * 2017-06-08 2018-12-18 卢海元 A kind of molecular targeted immune oxygen therapy drug of AIDS virus and preparation method thereof
CN112168841A (en) * 2019-07-05 2021-01-05 卢序 Method for increasing bioavailability of nitric oxide in human

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4507285A (en) * 1982-04-10 1985-03-26 Kuehne Friedrich Wilhelm Stabilized activated oxygen and pharmaceutical compositions containing said stabilized activated oxygen
US4851222A (en) * 1988-01-27 1989-07-25 Oxo Chemie Gmbh Method of promoting regeneration of bone marrow
CN1456513A (en) * 2003-05-23 2003-11-19 秦瑞 Producing method and apparatus for liquid containing active oxygen

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4507285A (en) * 1982-04-10 1985-03-26 Kuehne Friedrich Wilhelm Stabilized activated oxygen and pharmaceutical compositions containing said stabilized activated oxygen
US4851222A (en) * 1988-01-27 1989-07-25 Oxo Chemie Gmbh Method of promoting regeneration of bone marrow
CN1456513A (en) * 2003-05-23 2003-11-19 秦瑞 Producing method and apparatus for liquid containing active oxygen

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
亚氯酸钠生产概况及其展望. 黄云翔.广东化工,第6期. 1997
亚氯酸钠生产概况及其展望. 黄云翔.广东化工,第6期. 1997 *

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