CN100516054C - 一种合成乙酰磺胺酸钾过程中的磺化环合工艺及该工艺的专用设备 - Google Patents
一种合成乙酰磺胺酸钾过程中的磺化环合工艺及该工艺的专用设备 Download PDFInfo
- Publication number
- CN100516054C CN100516054C CNB2006100961790A CN200610096179A CN100516054C CN 100516054 C CN100516054 C CN 100516054C CN B2006100961790 A CNB2006100961790 A CN B2006100961790A CN 200610096179 A CN200610096179 A CN 200610096179A CN 100516054 C CN100516054 C CN 100516054C
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- Prior art keywords
- reactor
- sulphonation
- ring closure
- pump
- condenser
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000000034 method Methods 0.000 title claims abstract description 10
- 238000006798 ring closing metathesis reaction Methods 0.000 title claims description 15
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 title 1
- 229910052700 potassium Inorganic materials 0.000 title 1
- 239000011591 potassium Substances 0.000 title 1
- 230000002194 synthesizing effect Effects 0.000 title 1
- 239000000463 material Substances 0.000 claims abstract description 19
- 238000006243 chemical reaction Methods 0.000 claims abstract description 18
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 15
- 230000015572 biosynthetic process Effects 0.000 claims abstract description 9
- 238000003786 synthesis reaction Methods 0.000 claims abstract description 9
- 238000005516 engineering process Methods 0.000 claims description 19
- 239000002994 raw material Substances 0.000 claims description 13
- 238000006277 sulfonation reaction Methods 0.000 claims description 12
- 238000007363 ring formation reaction Methods 0.000 claims description 11
- GLVUDVXMQACDGG-UHFFFAOYSA-N [K].C(C)(=O)C1=C(S(=O)(=O)O)C=CC(=C1)N Chemical compound [K].C(C)(=O)C1=C(S(=O)(=O)O)C=CC(=C1)N GLVUDVXMQACDGG-UHFFFAOYSA-N 0.000 claims description 7
- 238000002347 injection Methods 0.000 claims description 6
- 239000007924 injection Substances 0.000 claims description 6
- 230000008676 import Effects 0.000 claims description 4
- 239000007921 spray Substances 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 abstract description 10
- 238000003756 stirring Methods 0.000 abstract description 4
- 238000001816 cooling Methods 0.000 abstract description 2
- FNXIDRUUVHQLHR-UHFFFAOYSA-N C(C)(=O)OS(=O)(C1=CC=C(C=C1)N)=O.[K] Chemical compound C(C)(=O)OS(=O)(C1=CC=C(C=C1)N)=O.[K] FNXIDRUUVHQLHR-UHFFFAOYSA-N 0.000 abstract 1
- AKEJUJNQAAGONA-UHFFFAOYSA-N sulfur trioxide Chemical compound O=S(=O)=O AKEJUJNQAAGONA-UHFFFAOYSA-N 0.000 description 8
- WBZFUFAFFUEMEI-UHFFFAOYSA-M Acesulfame k Chemical compound [K+].CC1=CC(=O)[N-]S(=O)(=O)O1 WBZFUFAFFUEMEI-UHFFFAOYSA-M 0.000 description 3
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 3
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 description 3
- 229960004998 acesulfame potassium Drugs 0.000 description 3
- 235000010358 acesulfame potassium Nutrition 0.000 description 3
- 239000000619 acesulfame-K Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 230000007062 hydrolysis Effects 0.000 description 2
- 238000006460 hydrolysis reaction Methods 0.000 description 2
- 239000000376 reactant Substances 0.000 description 2
- XCVWCSLKKQOBGY-UHFFFAOYSA-N 2-acetyl-4-aminobenzenesulfonic acid Chemical compound CC(=O)C1=CC(N)=CC=C1S(O)(=O)=O XCVWCSLKKQOBGY-UHFFFAOYSA-N 0.000 description 1
- 229960005164 acesulfame Drugs 0.000 description 1
- YGCFIWIQZPHFLU-UHFFFAOYSA-N acesulfame Chemical compound CC1=CC(=O)NS(=O)(=O)O1 YGCFIWIQZPHFLU-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 239000012267 brine Substances 0.000 description 1
- 238000006555 catalytic reaction Methods 0.000 description 1
- 239000003518 caustics Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- WASQWSOJHCZDFK-UHFFFAOYSA-N diketene Chemical compound C=C1CC(=O)O1 WASQWSOJHCZDFK-UHFFFAOYSA-N 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- -1 oxygenant Substances 0.000 description 1
- 239000000779 smoke Substances 0.000 description 1
- HPALAKNZSZLMCH-UHFFFAOYSA-M sodium;chloride;hydrate Chemical compound O.[Na+].[Cl-] HPALAKNZSZLMCH-UHFFFAOYSA-M 0.000 description 1
- 238000010189 synthetic method Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D291/00—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms
- C07D291/02—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms not condensed with other rings
- C07D291/06—Six-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Description
Claims (3)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB2006100961790A CN100516054C (zh) | 2006-09-24 | 2006-09-24 | 一种合成乙酰磺胺酸钾过程中的磺化环合工艺及该工艺的专用设备 |
US11/856,969 US7829701B2 (en) | 2006-09-24 | 2007-09-18 | Process for continuous production of the salts of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2,-dioxide |
US12/895,179 US8182756B2 (en) | 2006-09-24 | 2010-09-30 | Apparatus for producing an intermediate in the synthesis of acesulfame potassium |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB2006100961790A CN100516054C (zh) | 2006-09-24 | 2006-09-24 | 一种合成乙酰磺胺酸钾过程中的磺化环合工艺及该工艺的专用设备 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1927850A CN1927850A (zh) | 2007-03-14 |
CN100516054C true CN100516054C (zh) | 2009-07-22 |
Family
ID=37858003
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB2006100961790A Active CN100516054C (zh) | 2006-09-24 | 2006-09-24 | 一种合成乙酰磺胺酸钾过程中的磺化环合工艺及该工艺的专用设备 |
Country Status (2)
Country | Link |
---|---|
US (2) | US7829701B2 (zh) |
CN (1) | CN100516054C (zh) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9024016B2 (en) | 2012-06-08 | 2015-05-05 | Nutrinova Nutrition Specialists & Food Ingredients GmbH | Process for producing acesulfame potassium |
CN103130743B (zh) * | 2012-11-11 | 2015-11-18 | 安徽金禾实业股份有限公司 | 安赛蜜环合连续生产方法 |
US10030000B2 (en) | 2016-09-21 | 2018-07-24 | Celanese International Corporation | Acesulfame potassium compositions and processes for producing same |
EP3319949B1 (en) | 2016-09-21 | 2020-07-22 | Celanese International Corporation | Acesulfame potassium compositions and processes for producing same |
HUE047858T2 (hu) * | 2016-09-21 | 2020-05-28 | Celanese Int Corp | Aceszulfám-kálium kompozíciók és eljárás ezek elõállítására |
PL3319948T3 (pl) | 2016-09-21 | 2021-12-27 | Celanese International Corporation | Kompozycje acesulfamu potasowego i sposoby ich wytwarzania |
US11434214B2 (en) | 2017-12-15 | 2022-09-06 | Chemadvice Gmbh | Process for the preparation of an acesulfame in a spray reactor having a specific velocity of flow |
CN108191790B (zh) * | 2018-01-13 | 2021-09-07 | 安徽金禾实业股份有限公司 | 一种安赛蜜生产中磺化微通道反应方法及装置 |
WO2019141369A1 (en) | 2018-01-18 | 2019-07-25 | Chemadvice Gmbh | Process for the preparation of an acesulfame with sulphuric acid processing |
CN112110876A (zh) * | 2020-09-26 | 2020-12-22 | 安徽金禾实业股份有限公司 | 一种安赛蜜生产中连续磺化环合的方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3427342A (en) * | 1962-12-12 | 1969-02-11 | Chemithon Corp | Continuous sulfonation process |
DE3410439A1 (de) | 1984-03-22 | 1985-09-26 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-on-2,2-dioxid und dessen nichttoxischen salzen sowie der dabei als zwischenprodukt(e) auftretenden acetoacetamind-n-sulfonsaeure(salze) |
DE3527070A1 (de) | 1985-07-29 | 1987-01-29 | Hoechst Ag | Verfahren zur herstellung von 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-on-2,2-dioxid |
TW223067B (zh) | 1992-03-17 | 1994-05-01 | Hoechst Ag | |
CN1336363A (zh) | 2001-07-25 | 2002-02-20 | 张元宾 | 乙酰磺胺酸钾的合成制备方法 |
US20060193896A1 (en) | 2005-02-25 | 2006-08-31 | Cadbury Adams Usa Llc | Process for manufacturing a delivery system for active components as part of an edible composition |
-
2006
- 2006-09-24 CN CNB2006100961790A patent/CN100516054C/zh active Active
-
2007
- 2007-09-18 US US11/856,969 patent/US7829701B2/en active Active
-
2010
- 2010-09-30 US US12/895,179 patent/US8182756B2/en not_active Expired - Fee Related
Non-Patent Citations (2)
Title |
---|
甲苯磺化反应工艺与设备的研究. 宋光复等.化学反应工程与工艺,第14卷第2期. 1998 |
甲苯磺化反应工艺与设备的研究. 宋光复等.化学反应工程与工艺,第14卷第2期. 1998 * |
Also Published As
Publication number | Publication date |
---|---|
CN1927850A (zh) | 2007-03-14 |
US20110020191A1 (en) | 2011-01-27 |
US20080076919A1 (en) | 2008-03-27 |
US8182756B2 (en) | 2012-05-22 |
US7829701B2 (en) | 2010-11-09 |
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Owner name: SUZHOU HAOBO TECHNOLOGY HOLDINGS CO., LTD. Free format text: FORMER NAME: ZHANGJIAGANG HAOBO CHEMICAL PRODUCT CO., LTD. |
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Address after: 215633, Nansha, Jiangsu Province, Zhangjiagang Town, three gold road Patentee after: SUZHOU HOPE TECHNOLOGY CO.,LTD. Address before: 215633, Nansha, Jiangsu Province, Zhangjiagang Town, three gold road Patentee before: Zhangjiagang Haobo Chemical Co.,Ltd. |
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PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Sulphonation ring closure process of synthesizing potassium acetylsulfamilate and special device for the same Effective date of registration: 20150209 Granted publication date: 20090722 Pledgee: Bank of Communications Ltd. Zhangjiagang branch Pledgor: SUZHOU HOPE TECHNOLOGY CO.,LTD. Registration number: 2015990000121 |
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Inventor after: Liu Jicai Inventor after: Liu Huixing Inventor after: Liu Yilong Inventor after: Bao Zhongxiang Inventor before: Liu Jicai Inventor before: Kong Lingwen Inventor before: Bao Zhongxiang Inventor before: Chen Xiaoping |
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Date of cancellation: 20220822 Granted publication date: 20090722 Pledgee: Bank of Communications Ltd. Zhangjiagang branch Pledgor: SUZHOU HOPE TECHNOLOGY CO.,LTD. Registration number: 2015990000121 |
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Effective date of registration: 20221024 Address after: 226009 No. 968, Jiangshan Road, Nantong Economic and Technological Development Zone, Nantong City, Jiangsu Province Patentee after: NANTONG HONGXIN CHEMICAL Co.,Ltd. Address before: 215633, Nansha, Jiangsu Province, Zhangjiagang Town, three gold road Patentee before: SUZHOU HOPE TECHNOLOGY CO.,LTD. |
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