CN100515517C - Method and device for local heating of animal inner body - Google Patents
Method and device for local heating of animal inner body Download PDFInfo
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- CN100515517C CN100515517C CNB2005100960488A CN200510096048A CN100515517C CN 100515517 C CN100515517 C CN 100515517C CN B2005100960488 A CNB2005100960488 A CN B2005100960488A CN 200510096048 A CN200510096048 A CN 200510096048A CN 100515517 C CN100515517 C CN 100515517C
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- element heater
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Abstract
The present invention discloses method and device for local heating of animal body. After heating element of ferromagnetic material is set in the part to be heated, alternate magnetic field is established in the corresponding part, so that eddy flow is formed in the heating element under the action of the alternate magnetic field to heat the local part. The device of the present invention consists of HF power generator, solenoid formed via winding wire conductor or tubular conductor, and heating element capable of being set temporarily inside animal body. The interval between the two magnetic poles of the solenoid forms the space to hold the animal body, and inside the solenoid, magnetic core of soft ferromagnetic material may be set.
Description
Technical field
The present invention relates to a kind of in the animal body, particularly in the human body, method that some ad-hoc location fixes a point to heat and device.
Background technology
In animal body, particularly diseased region specific in the human body being heated is a kind of effective treatment means.For example adopt local heat, can make its tissue necrosis, and effectively kill tumor cell for occupying lesions such as tumors.
In the prior art method of carrying out local heat in the body there is following a few class:
1, microwave heating
This method is a launched microwave bundle in body, under the frequency electromagnetic waves effect, the intravital hydrone of animal, protein molecule isopolarity molecule polarize, and produce vibration with the frequency in outfield, because the dipole of vibration and adjacent molecule produce the friction collision, produce heat.For example Chinese patent application 99117361.9,02806478.X
The deficiency of this method is that the human body on the path of microwave penetration all is heated, and the injury maximum that is subjected to of body surface, and its penetration depth is little, the localization heating of can't accomplishing to fix a point.
2, radio-frequency current heating
Adopt operation method that electrode is implanted and be heated the position,, make ion in the body under the driving of electric field, produce heat with molecule friction on every side in the external radio-frequency voltage that on electrode, adds.This heating comes down to have the impedance electrolyte with being organized as of human body, produces ohm heat.
The deficiency of this method is that its heating region is the disperse distribution, so its heating region does not have strict border; But also need with the method implant electrode of performing the operation.
3, magnetic fluid heating
This method is that trickle ferromagnetic material granule (its particle scale generally is a nanoscale) and water are formed suspension (being called as magnetic fluid), again this suspension is injected into the position that needs heating, again at the interaction in vitro alternating magnetic field, utilize the hysteresis effect of alternating magnetic field on ferromagnetic material, produce heat.As " progress of tumor magnetic thermotherapy equipment research and development ", Luoyang college journal the 19th the 4th phase of volume of December in 2004.
The deficiency of this method is: 1) need very strong alternating magnetic field.Under present human body electromagnetic field allowed to bear, its heat production is very little.2), can produce illeffects after it enters in the body, and be difficult to discharge because the used magnetic material is a nano-particle.
4, high-energy ultrasonic focuses on heating
Chinese patent 99102923.2 disclosed high-energy ultrasonic external focusing heat therapy machine power ultrasonic transmitters are intensive fixedly piezoelectric patches on the hemispherical inner face, are focused in vivo by each piezoelectric patches generation ultrasonic beam and heat.
The deficiency of this patent is that ultrasound wave decay in vivo is bigger.Its technology realizes comparatively difficulty on the other hand.In addition, equipment used in the prior art is comparatively complicated, and its manufacture difficulty is bigger.
Summary of the invention
The invention provides a kind of new method that regional area in the animal body is heated, and the employed device of this method, this method and device can overcome the deficiencies in the prior art, its device is simple than prior art, make more or less freely, can regional area specific in the body effectively be heated, and the tissue around it is not had influence.
Method of the present invention is the heating element heater of temporarily inserting ferromagnetic material at need heating position, for example adopt the method for puncture, be heated the position spicule that to thrust one or more its front ends be ferromagnetic material, then outside animal body and be heated corresponding position, position and set up alternating magnetic field, make the heating element heater of temporarily being inserted under action of alternating magnetic field, form eddy current, produce heat, heat being heated the position.
Because method of the present invention is the relevant position alternating magnetic field that is heated the position outside animal body, and insert heating element heater at the position of needs heating temporarily, heating element heater produces heat under action of alternating magnetic field like this, can be with this position heating, its area heated promptly is formed in the zone of heating element heater by strictness, when adding hot work and finish, heating element heater can be extracted, so heating element heater can not be stranded in the negative influence of generation in the body at " postoperative "; On the other hand owing to be that heating element heater is directly inserted in the body temporarily, the therefore influence of not heated the position and the body surface degree of depth.
The present invention adopts high-frequency alternating magnetic field, utilizes eddy current effect to heat, and best heats can be arranged.
The solenoid that device of the present invention turns to by high frequency power generator, with line conductor or tubular shape conductor, and can implant the intravital heating element heater of animal temporarily and constitute the space of wherein solenoidal two magnetic pole gaps for holding animal body.
The present invention adopts tubular shape conductor, as adopting copper pipe, mainly is to consider to solve the heat problem of conductor when work, by tubular shape conductor, is produced heat with cooling water to take away.The used power generator of the present invention can adopt existing teach book or the disclosed technology contents of relevant handbook, particularly can use multiple model approved product, as the GPH-16 type product of Zhengzhou Ri Jia Electronics Co., Ltd. production.Power generator frequency of the present invention will have best cost performance in 30～100KHz scope.
The magnetic core that the mid-useful soft iron magnetic material of above-mentioned solenoid of the present invention is made with the raising magnetic field intensity, and concentrates the magnetic line of force.Like this, be magnetic pole with the termination of two magnetic cores, will be heated the zone and place interpolar, have bigger efficient.The used core material suggestion of the present invention adopts manganese-zinc ferrite to make.
The class spicule that the used heating element heater of the present invention is made with ferromagnetic material for its head, the bar made from nonferromagnetic material of not holding of spicule is fixed, and is provided with adiabator at the standing part of bar and spicule.This in use spicule can be directly inserts by body surface be heated the position, as thermal source, and after heating is finished, can directly pull out in body when heating " operation ".The size of spicule and shape can be determined in advance according to the situation that is heated the position.For bigger heating part, position, also can adopt the mode of inserting a plurality of elements to solve.For example by the periphery heating element heater that is heated the zone, simultaneously in the inside that has been heated the zone insert some heating element heaters, heating region all is heated to reach desired physiologic effect.
The nonferromagnetic material bar that heating element heater of the present invention is not held is an austenitic stainless steel, perhaps adopts metal alloy compositions such as aluminum, titanium, magnesium, also can adopt nonmetallic macromolecular material.
The present invention compared with prior art has following advantage:
1, its heat production theory and practice is all very ripe, does not have technical problem in the enforcement;
2, its to install relative prior art more simple, it is cheap for manufacturing cost;
3, heating element heater only is to insert in the body temporarily, can pull out after implementing to add hot work accordingly, do not stay in body, so heating element heater itself can be to exerting an influence in the body;
4, the relative prior art of its heats is better, and theoretically, the temperature of its heating can reach hundreds of degree in regional area, and this is difficult to realize in the prior art;
5, the present invention can form the heating field of location localization constant temperature in vivo, as utilizes methods such as existing CT, localization by ultrasonic to determine the position that heating element heater should insert; At a plurality of heating element heaters of insertion that are heated the zone, constitute the heating region of given shape;
6, it is minimum to the damage of in-vivo tissue to implement heating, its heating element heater only insert quite paracentesis or intramuscular injection, can be called Minimally Invasive Surgery;
7, by after the embodiment that chats as seen, the Temperature Distribution gradient that the present invention's heating is produced is extremely steep, therefore the whole process that adds hot work and postoperative to human body in the influence of normal structure also very little.
8, the present invention can adopt the plug-in type thermometric and realize temperature control, also can adopt non-insertion thermometric, control technology.When the present invention adopts these technical measures, can implement temperature survey, and in time feed back to high frequency power generator, realize temperature controlling heating region;
9, the present invention is in heating process, and high-frequency alternating magnetic field only acts on the part of animal body, and intensity a little less than.Therefore, the electromagnetic field of high frequency can be ignored the influence of organism.
Description of drawings
Accompanying drawing 1 is a solenoid and the sketch map of implementing heated condition in the device of the present invention, and accompanying drawing 2 be a heating element heater sketch map of the present invention, and accompanying drawing 3 is the thermograde variation diagram when testing measured heating.
Among the figure: 1 is solenoid, and 2 is magnetic core, and 3 are selected heating region, 4 is magnetic pole, and 5 is the solenoid terminals, and 6 is the bar of spicule tail end, the 7 spicule heads of making for Antaciron, 8 for being located at the adiabator between bar and head, and 9 for being used to prevent the fixture of head and bar disengaging.
The specific embodiment
Below in conjunction with the embodiment of an accompanying drawing and an illustrative and the data of actual measurement thereof the present invention is further specified.
Referring to Fig. 1, to make on the magnetic core 2 that is the U type with manganese-zinc ferrite at one and to be provided with solenoid 1, two ends of magnetic core 2 form two magnetic poles 4, and the terminals 5 of solenoid 1 connect high frequency power generator (expression among Fig. 1).In the gap of 4 of magnetic poles is the position that human body is placed.Down, two magnetic poles 4 should be in the relevant position of chosen heating region 3, as shown in working order.
An embodiment of heating element heater of the present invention is referring to accompanying drawing 2.Wherein the front end at a bar 6 made from nonferromugnetic material is fixed with a head 7 made from Antaciron (can directly use the silicon steel material), forms a spicule.The material suggestion employing polytetrafluoroethylmaterial material of bar 6 described here etc. has superior heat resistance and material better firm, intensity.Bearing on 7 on bar 6 and head is provided with adiabator, as macromolecular material or the nonmetallic inorganic material that better heat-insulating property is arranged, perhaps organic material.For 7 on anti-stopping bar 6 and head break away from when the plug operation, in the present embodiment at bar 6 and portion 7 cooperation places are had a hole, and pass this hole with an inserts 9, make combination between the two more reliable.
An illustrative embodiment of the present invention is as follows:
The electromagnetic oven of selling with existing market is a power generator, and its output is led line Chan on the skeleton of a straight-tube shape, forms heater.
With nylon wire is bar, and the diameter that its front end is put a tip is that 1.5 millimeters long are 10 millimeters ferrum pin, forms heating element heater.
The fresh in vitro muscle of getting 5 * 5 * 5 centimetres of sizes is for being tried thing.
In being tried the mid-depth place of muscle, evenly insert six roots of sensation heating element heater on by the circle of 20 mm dias before the test,, and insert a heating element heater again at circle centre position.Multiple spot insertion copper-constantan thermocouple carries out thermometric near the heating element heater that is inserted simultaneously.The diameter of thermocouple is 1.2mm.
To be tried muscle during test and insert in the solenoid, opening power is carried out thermometric simultaneously.After heat run, cut open and tried muscle as seen, form about 30 millimeters an of diameter, highly be about 20 millimeters at the heating position, sharply marginated column cold cuts district, and that the muscle of other parts is still kept intact is constant.
Measurement in the test shows, formed an approximate isothermal thermal treatment zone near center (i.e. the heating element heater place of Cha Ruing), its temperature reaches 90 ℃, and the thermal treatment zone to add the boundary clear, the gradient that temperature descends beyond on this border is very steep, and the 5 millimeters outer temperature in border do not have two with degree of being subjected to human body temperature.Referring to Fig. 3.Owing to be subjected to the restriction of condition, can't make test corresponding with device of the present invention.But this result of the test has been enough to illustrate effect of the present invention and feasibility.
Claims (9)
1, carry out the device of local heat in animal body, it is characterized in that device is by high frequency power generator, the solenoid that turns to line conductor or tubular shape conductor, and can implant the spicule that intravital its head of animal is made with ferromagnetic material temporarily, the bar that the end of spicule is made with nonferromagnetic material is fixed, standing part at bar and spicule has the heating element heater of adiabator to constitute, the space of wherein solenoidal two magnetic pole gaps for holding animal body, in the time of in working order heating element heater is thrust the position that is heated of animal body, and animal is heated the position is placed among two magnetic pole gaps, be positioned at the intravital heating element heater of animal and be heated by between two magnetic poles, producing alternating magnetic field under high frequency power generator and solenoidal line conductor or the tubular shape conductor effect, making.
2,1 described device as requested, the power generator frequency that it is characterized in that device is 30～100KHz.
3, device according to claim 2 is characterized in that the magnetic core that the mid-useful soft iron magnetic material of solenoid is wherein made.
4, device according to claim 3 is characterized in that the used core material of solenoid adopts manganese-zinc ferrite to make.
5,, it is characterized in that the nonferromagnetic material bar that heating element heater is not held is an austenitic stainless steel according to the described arbitrary device of claim 1 to 4.
6,, it is characterized in that the nonferromagnetic material bar that heating element heater is not held is nonmetallic macromolecular material according to the described arbitrary device of claim 1 to 4.
7,, it is characterized in that the nonferromagnetic material bar that heating element heater is not held is an aluminum alloy materials according to the described arbitrary device of claim 1 to 4.
8,, it is characterized in that the nonferromagnetic material bar that heating element heater is not held is a titanium alloy material according to the described arbitrary device of claim 1 to 4.
9,, it is characterized in that the nonferromagnetic material bar that heating element heater is not held is a magnesium alloy materials according to the described arbitrary device of claim 1 to 4.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100960488A CN100515517C (en) | 2005-09-16 | 2005-09-16 | Method and device for local heating of animal inner body |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100960488A CN100515517C (en) | 2005-09-16 | 2005-09-16 | Method and device for local heating of animal inner body |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1748813A CN1748813A (en) | 2006-03-22 |
| CN100515517C true CN100515517C (en) | 2009-07-22 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNB2005100960488A Expired - Fee Related CN100515517C (en) | 2005-09-16 | 2005-09-16 | Method and device for local heating of animal inner body |
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| CN (1) | CN100515517C (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104138636A (en) * | 2013-05-11 | 2014-11-12 | 赵力波 | Instrument for promoting blood circulation in human body |
| CN107164221B (en) * | 2017-04-28 | 2019-07-26 | 齐齐哈尔医学院 | The device of electromagnetic force heating damage spin dialysis cancer cells in blood |
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- 2005-09-16 CN CNB2005100960488A patent/CN100515517C/en not_active Expired - Fee Related
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Granted publication date: 20090722 Termination date: 20110916 |