CN100497628C - 分离的编码t细胞诱导因子或白介素-21的核酸分子,其编码的蛋白和其应用 - Google Patents

分离的编码t细胞诱导因子或白介素-21的核酸分子,其编码的蛋白和其应用 Download PDF

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CN100497628C
CN100497628C CNB2005101169978A CN200510116997A CN100497628C CN 100497628 C CN100497628 C CN 100497628C CN B2005101169978 A CNB2005101169978 A CN B2005101169978A CN 200510116997 A CN200510116997 A CN 200510116997A CN 100497628 C CN100497628 C CN 100497628C
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tif
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cells
dna
molecules
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CN1796558A (zh
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劳尔·杜穆蒂尔
琼-克里斯托弗·雷诺尔德
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Wyeth LLC
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P5/14Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
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    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047Cells of the immune system
    • G01N33/505Cells of the immune system involving T-cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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CNB2005101169978A 2000-07-27 2001-06-27 分离的编码t细胞诱导因子或白介素-21的核酸分子,其编码的蛋白和其应用 Expired - Fee Related CN100497628C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62661700A 2000-07-27 2000-07-27
US09/626,617 2000-07-27

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CNB018131255A Division CN100448994C (zh) 2000-07-27 2001-06-27 分离的编码t细胞诱导因子或白介素-21的核酸分子,其编码的蛋白和其应用

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CN1796558A CN1796558A (zh) 2006-07-05
CN100497628C true CN100497628C (zh) 2009-06-10

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CNB2005101169978A Expired - Fee Related CN100497628C (zh) 2000-07-27 2001-06-27 分离的编码t细胞诱导因子或白介素-21的核酸分子,其编码的蛋白和其应用
CNA2008101764854A Pending CN101423551A (zh) 2000-07-27 2001-06-27 分离的编码t细胞诱导因子或白介素-21的核酸分子,其编码的蛋白和其应用
CNB018131255A Expired - Fee Related CN100448994C (zh) 2000-07-27 2001-06-27 分离的编码t细胞诱导因子或白介素-21的核酸分子,其编码的蛋白和其应用

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CNA2008101764854A Pending CN101423551A (zh) 2000-07-27 2001-06-27 分离的编码t细胞诱导因子或白介素-21的核酸分子,其编码的蛋白和其应用
CNB018131255A Expired - Fee Related CN100448994C (zh) 2000-07-27 2001-06-27 分离的编码t细胞诱导因子或白介素-21的核酸分子,其编码的蛋白和其应用

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EP (2) EP1305419B1 (https=)
JP (1) JP4113773B2 (https=)
CN (3) CN100497628C (https=)
AT (2) ATE365801T1 (https=)
AU (1) AU7303301A (https=)
CA (1) CA2416820A1 (https=)
DE (2) DE60129137D1 (https=)
ES (1) ES2349312T3 (https=)
WO (1) WO2002010393A2 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7307161B1 (en) 1999-04-28 2007-12-11 Genetics Institute, Llc Human Gil-19/AE289 polynucleotides
US6939545B2 (en) 1999-04-28 2005-09-06 Genetics Institute, Llc Composition and method for treating inflammatory disorders
US20030170823A1 (en) 1999-12-23 2003-09-11 Presnell Scott R. Novel cytokine ZCYTO18
US20030023033A1 (en) * 2001-07-26 2003-01-30 Laure Dumoutier Novel class II cytokine receptors and uses thereof
US20030012788A1 (en) 2000-07-27 2003-01-16 Jean-Christophe Renauld Method for influencing kinase pathways with IL-22
US20060083713A1 (en) * 2000-10-13 2006-04-20 Eli Lilly And Company Methods of using a human il-17 related polypeptide to treat disease
US7638604B2 (en) 2001-02-23 2009-12-29 Genetics Institute, Llc Monoclonal antibodies against interleukin-22
EP1546358A4 (en) 2002-03-22 2006-06-07 Zymogenetics Inc ANTI-IL-TIF ANTIBODIES AND METHOD FOR USE ON INFLAMMATION
WO2004003156A2 (en) 2002-07-01 2004-01-08 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Il-21 as a regulator of immunoglobin production
EP1562587A4 (en) * 2002-09-11 2006-07-19 Genentech Inc NEW COMPOSITIONS AND METHOD FOR THE TREATMENT OF IMMUNOMOTICS
PL376118A1 (en) * 2002-10-11 2005-12-12 Novo Nordisk A/S Treatment of allergic conditions by use of il 21
KR20050065590A (ko) * 2002-10-11 2005-06-29 노보 노르디스크 에이/에스 Il 21을 이용한 알레르기 상태의 치료법
ES2354693T3 (es) * 2003-06-23 2011-03-17 Genetics Institute, Llc Anticuerpos contra interleucina-22 y usos para ellos.
EP1954719A2 (en) 2005-12-02 2008-08-13 Genentech Inc. Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling involving antibodies that bind to il-22 and il-22r
TWI417301B (zh) 2006-02-21 2013-12-01 Wyeth Corp 對抗人類介白素-22(il-22)之抗體及其用途
TW200744634A (en) 2006-02-21 2007-12-16 Wyeth Corp Methods of using antibodies against human IL-22
IT1404858B1 (it) 2011-02-21 2013-12-09 Milano Politecnico Supporto anti-sismico.
US20240026014A1 (en) * 2020-08-05 2024-01-25 Synthekine, Inc. Compositions and methods related to receptor pairings

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843697A (en) 1996-07-17 1998-12-01 University Of Medicine And Dentistry Of New Jersey Cells expressing IL-10 receptor and the CRFB4 gene product, an IL-10 receptor accessory protein
DE19848683B4 (de) 1998-10-22 2004-05-06 Basf Ag Verbundschichtplatte
EP1131333B1 (en) * 1998-10-26 2010-06-02 Wyeth a Corporation of the State of Delaware ISOLATED NUCLEIC ACID MOLECULES WHICH ENCODE T CELL INDUCIBLE FACTORS (TIFs), THE PROTEINS ENCODED, AND USES THEREOF
BR0010097A (pt) * 1999-04-28 2002-02-13 Genetics Inst Polinucleotìdeo isolado; célula hospedeira; processo para a produção de uma proteìna codificada pelo polinucleotìdeo; proteìna; composição; e; anticorpo
AU5047600A (en) * 1999-05-27 2000-12-18 Schering Corporation Mammalian interleukin-10 homologs: il-d110 and il-d210
US6897292B2 (en) * 1999-12-03 2005-05-24 Zymogenetics, Inc. Human cytokine receptor

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Cloning and Characterization of IL-10-Related TCell-DerivedInducible Factor (IL-TIF), a Novel CytokineStructurallyRelated to IL-10 and Inducible by IL-9. Laure Dumoutier等.J. of Immunology,Vol.164 . 2000
Cloning and Characterization of IL-10-Related TCell-DerivedInducible Factor (IL-TIF), a Novel CytokineStructurallyRelated to IL-10 and Inducible by IL-9. Laure Dumoutier等.J. of Immunology,Vol.164 . 2000 *

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Publication number Publication date
JP4113773B2 (ja) 2008-07-09
JP2004504842A (ja) 2004-02-19
CN100448994C (zh) 2009-01-07
AU7303301A (en) 2002-02-13
ATE478148T1 (de) 2010-09-15
EP1806404A1 (en) 2007-07-11
WO2002010393A2 (en) 2002-02-07
EP1806404B1 (en) 2010-08-18
CN1443241A (zh) 2003-09-17
ES2349312T3 (es) 2010-12-29
DE60142861D1 (de) 2010-09-30
WO2002010393A3 (en) 2003-01-30
CA2416820A1 (en) 2002-02-07
ATE365801T1 (de) 2007-07-15
EP1305419B1 (en) 2007-06-27
CN1796558A (zh) 2006-07-05
CN101423551A (zh) 2009-05-06
DE60129137D1 (de) 2007-08-09
EP1305419A2 (en) 2003-05-02

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