CN100493542C - Traditional Chinese medicine for treating hemopathy - Google Patents

Abstract

The invention relates to a Chinese medicament for treating nosohemia, which is prepared from placenta powder, tortoise-plastron glue, white atractylodes rhizome, donkey-hide gelatin, carbonized hair,schisandra fruit, deer horn gum, garden burnet root, Chinese angelica root, dipsacus root, flatstem milkvetch seed, prepared rhizome of rehmannia, scrophularia root and Cistanche deserticola.

Description

The hemopathic Chinese medicine of a kind of treatment

Technical field: the present invention relates to the hemopathic Chinese medicine of a kind of treatment.

Background technology: at present, during the treatment hematopathy has, two kinds of methods of doctor trained in Western medicine, doctor trained in Western medicine is mainly with chemotherapy, the plain medication treatment of flesh.This method side effect is big, destroys immune function of human body, also can cause other sick generation, also has treatment by Chinese herbs hemopathic, but all is to keep or alleviate present situation, can not cure.

Summary of the invention: the objective of the invention is to overcome above-mentioned shortcoming, provide a kind of treatment hemopathic Chinese medicine, its good effect has no side effect.The object of the present invention is achieved like this: it is that raw material processing is formulated by 0.8-1 liang of Placenta Hominis powder, Colla Plastri Testudinis 3-5 money, Rhizoma Atractylodis Macrocephalae charcoal 3-5 money, Colla Corii Asini 3-5 money, Crinis Carbonisatus 3-5 money, Fructus Schisandrae Chinensis 3-5 money, Colla cornus cervi 3-5 money, charred Radix Sanguisorbae 3-5 money, Radix Angelicae Sinensis 3-5 money, Radix Dipsaci 3-5 money, Semen Astragali Complanati 3-5 money, Radix Rehmanniae Preparata 3-5 money, Radix Scrophulariae 3-5 money, Herba Cistanches 4-6 money for the hemopathic Chinese medicine of a kind of treatment.Its preparation method is singly to put standby Placenta Hominis powder for 0.8-1 liang; Colla Plastri Testudinis 3-5 money, Colla Corii Asini 3-5 money, Colla cornus cervi 3-5 money are mixed put together, adds after 3 liang of water heated and stirred dissolve out, adding Crinis Carbonisatus 3-5 money are mixed thoroughly standby; Rhizoma Atractylodis Macrocephalae charcoal 3-5 money, Fructus Schisandrae Chinensis 3-5 money, charred Radix Sanguisorbae 3-5 money, Radix Angelicae Sinensis 3-5 money, Radix Dipsaci 3-5 money, Semen Astragali Complanati 3-5 money, Radix Rehmanniae Preparata 3-5 money, Radix Scrophulariae 3-5 money, Herba Cistanches 4-6 Qian Jiuwei medicines are put into drug-decocting pot and added water, water did not have medicine, after opening with baked wheaten cake, boiling was fried in shallow oil 25-30 minutes, soup is poured out put into container, and then add water, water did not have medicine, after opening with baked wheaten cake, boiling was fried in shallow oil 30-40 minutes, fried in shallow oil back secondary decoction and mixed and get final product.This Chinese medicine is secret prescription handed down in the family from generation to generation, all cures through the treatment of suffering from aplastic anemia and thrombocytopenia purpura patient for nearly hundred examples, is summarized as follows through clinical observation result:

Before one patient takes medicine:

1, hemogram: (1) hemoglobin decrease speed is fast;

(2) reticulocyte＜1%, absolute value＜15 * 10 ⁹/ L;

(3) hemocyte obviously reduces, neutrophilic granulocyte absolute value＜0.5 * 10 ⁹/ L;

(4) platelet＜20 * 10 ⁹/ L.

2, bone marrow smear: the position hypoplasia of bone marrow multi-section, three is that hematopoietic cell obviously reduces, non-hematopoietic cell increases, lymphocytosis, non-hematopoietic cell increases in the bone marrow granule.

After the patient took medicine: anemia infected visceral hemorrhage and disappears, and the quantity and the functional rehabilitation of hematopoietic stem cell are normal, and every index reaches:

(1) hemoglobin reaches 120 ⁹/ L;

(2) hemocyte reaches 4 * 10 ⁹/ L;

(3) platelet reaches 80 * 10 ⁹More than/the L.

Placenta Hominis powder in this medicine fills blood, the kidney tonifying essence, the Colla Corii Asini nourishing blood hemostasis, nourishing YIN and moistening the lung, the Colla cornus cervi invigorating the liver and kidney, benefiting essence-blood, kind hemostasis, the Colla Plastri Testudinis replenishing kidney and strengthening bone, nourishing YIN and benefiting blood, hemostasis, Crinis Carbonisatus hemostasis dissipating blood stasis, the nourishing YIN diuresis, the charred Radix Sanguisorbae removing heat from blood, hemostasis, Rhizoma Atractylodis Macrocephalae charcoal air making-up and spleen enlivening, antidiarrheal, the Herba Cistanches kidney invigorating and YANG supporting, nourish essence and blood, the Radix Dipsaci invigorating the liver and kidney, the promoting the circulation of blood arteries and veins, reuniting the fractured tendons and bones, the Semen Astragali Complanati tonifying the kidney to consolidate the essence, nourishing the liver to improve visual acuity, the Chinese Angelica blood replonishing tonify deficiency, promoting blood circulation and stopping pain, loosening bowel to relieve constipation, the Radix Scrophulariae clearing away heat and cooling blood, detoxicating and resolving stagnation of pathogens, YIN nourishing and the production of body fluid promoting, the Radix Rehmanniae Preparata nourishing the blood and yin, vital essence replenishing and marrow benifiting, the Fructus Schisandrae Chinensis tonifying the lung and nourishing the kidney, controlling nocturnal emission with astringent drugs antidiarrheal, feel at ease to calm the nerves.It can adjust patient's allomeric function this Chinese medicine, with heat clearing away, removing heat from blood, hemostasis, reinforcing the kidney and supporting YANG, warming middle-JIAO and strengthening the spleen, benefiting qi and nourishing blood, and treating both the principal and the secondary aspects of a disease at the same time, the effect of play hemostasis, hemopoietic, nourishing blood makes patient recover hemopoietic function, reaches recovery from illness.This medication is imitated definite, and is safe and reliable, has no side effect.This side is reported as follows through preclinical medicine institute of Jiamusi University laboratory test:

Experiment material

1, be subjected to the reagent product: the hemopathic Chinese medicine decoction of a kind of treatment, 255g crude drug/200mL, draft usage and consumption: oral, 100mL/ time, 2 times/day.

2, laboratory animal: pure Kunming kind white mice, body weight 20 ± 2g, male and female half and half are provided by Jiamusi University's Experimental Animal Center, meet requirement of experiment.

Experimental technique and result

1, LD ₅₀Measure: experiment purpose is the toxic reaction of animal behind the observation single administration and measures its LD ₅₀

Get 9 of mices, be divided into 3 groups at random, every group 3, get and be subjected to reagent liquid to be concentrated into 12.5g crude drug/mL, ratio with 1:0.5 must concentration be the medicinal liquid of 6.25g crude drug/mL and 3.125g crude drug/mL by hanging down than dilution method in addition again, the medicinal liquid of 3 kinds of variable concentrations is irritated stomach respectively give respectively to organize mice, the 0.2mL/10g body weight, each treated animal does not all have death as a result.

Other gets 10 of mices, irritate stomach and give the high concentration (medicinal liquid of 12.5g crude drug/mL), 0.2mL/10g body weight, observed 7 after the administration, record animal dead situation and toxic reaction situation, none animal dead is not also seen the untoward reaction that toxicity causes as a result, as seen be subjected to reagent thing toxicity lower, fail to measure its LD ₅₀

2, maximum tolerance determination: can't measure LD because of being subjected to reagent substrate concentration and volume restrictions ₅₀, done the maximum tolerance determination of single administration for this reason.

Get 20 of mices, male and female half and half are put in the laboratory and are raised, and observe 3, get the high concentration (medicinal liquid of 12.5g crude drug/mL), 0.2mL/10g body weight (250g crude drug/kg body weight) is irritated stomach, observes toxic reaction and death condition in 7 days after the administration, visible mice activity freely, outward appearance, feed, Excreta and breath state etc. are all normal, clean and tidy, glossy by hair, nose, eye, oral cavity no abnormality seen secretions, none is only dead for animal subject.

Relevant experimental data substitution following formula is calculated:

$=\frac{12.5(g/\mathrm{mL})\×0.4\left(\mathrm{mL}\right)}{20\left(g\right)}\×\frac{60000\left(g\right)}{127.5\left(g\right)}$

Result of calculation, the maximum tolerated dose of mice are 117.6 times of clinical adult's dosage, show that to be subjected to reagent thing toxicity very little, are medicine safe in utilization.

The specific embodiment:

Embodiment 1, is the optimum selection prescription.

Get 1 liang of Placenta Hominis powder, Colla Plastri Testudinis 4 money, Rhizoma Atractylodis Macrocephalae charcoal 4 money, Colla Corii Asini 4 money, Crinis Carbonisatus 4 money, Fructus Schisandrae Chinensis 4 money, Colla cornus cervi 4 money, charred Radix Sanguisorbae 4 money, Radix Angelicae Sinensis 4 money, Radix Dipsaci 4 money, Semen Astragali Complanati 4 money, Radix Rehmanniae Preparata 4 money, Radix Scrophulariae 4 money, Herba Cistanches 5 money.

Embodiment 2, get 0.8 liang of Placenta Hominis powder, Colla Plastri Testudinis 3 money, Rhizoma Atractylodis Macrocephalae charcoal 3 money, Colla Corii Asini 3 money, Crinis Carbonisatus 3 money, Fructus Schisandrae Chinensis 3 money, Colla cornus cervi 3 money, charred Radix Sanguisorbae 3 money, Radix Angelicae Sinensis 3 money, Radix Dipsaci 3 money, Semen Astragali Complanati 3 money, Radix Rehmanniae Preparata 3 money, Radix Scrophulariae 3 money, Herba Cistanches 4 money.

Embodiment 3, get 0.9 liang of Placenta Hominis powder, Colla Plastri Testudinis 5 money, Rhizoma Atractylodis Macrocephalae charcoal 5 money, Colla Corii Asini 5 money, Crinis Carbonisatus 5 money, Fructus Schisandrae Chinensis 5 money, Colla cornus cervi 5 money, charred Radix Sanguisorbae 5 money, Radix Angelicae Sinensis 5 money, Radix Dipsaci 5 money, Semen Astragali Complanati 5 money, Radix Rehmanniae Preparata 5 money, Radix Scrophulariae 5 money, Herba Cistanches 6 money.

More than the preparation method of three embodiment be:

A. put the Placenta Hominis powder list of described weight proportion standby;

B. Colla Plastri Testudinis, Colla Corii Asini, the Colla cornus cervi with described weight proportion mixes and puts together, adds 3 liang of water, and after heated and stirred was dissolved out, the Crinis Carbonisatus that adds described weight was mixed thoroughly standby;

C. nine medicines of Rhizoma Atractylodis Macrocephalae charcoal, Fructus Schisandrae Chinensis, charred Radix Sanguisorbae, Radix Angelicae Sinensis, Radix Dipsaci, Semen Astragali Complanati, Radix Rehmanniae Preparata, Radix Scrophulariae, Herba Cistanches of described weight proportion are put into drug-decocting pot and add water, water did not have medicine, after opening with baked wheaten cake, boiling was fried in shallow oil 25-30 minutes, soup is poured out put into container, and then add water, water did not have medicine, after opening with baked wheaten cake, boiling was fried in shallow oil 30 1 40 minutes, fried in shallow oil back secondary decoction and mixed and get final product.

Instructions of taking:

1, Placenta Hominis powder is divided each 1 part of two parts of morning and evening, use warm water delivery service.

2, will change good Crinis Carbonisatus, Colla Plastri Testudinis, Colla Corii Asini, Colla cornus cervi soup and be divided into two parts, sooner or later under each 1 part of clothes.

3, nine medicine soup will frying in shallow oil divide two parts, sooner or later under each 1 part of clothes.

4, every day obeyed twice by the powder of making more than, glue soup, medicine soup, early obeys 1 part 1 hour ante cibum, and preceding 1 hour clothes of supper get final product for 1 part.

But 5, children taking decrement.

Attention: the patient did not do the best results of taking of chemotherapy from falling ill, stop during taking this medicine with other Western medicine or chemicotherapy.

This medicine is to congenital patient's unsatisfactory curative effect.

Claims (2)

1, the hemopathic Chinese medicine of a kind of treatment is characterized in that it is to be made by the medicine of following weight: 0.8-1 liang of Placenta Hominis powder, Colla Plastri Testudinis 3-5 money, Rhizoma Atractylodis Macrocephalae charcoal 3-5 money, Colla Corii Asini 3-5 money, Crinis Carbonisatus 3-5 money, Fructus Schisandrae Chinensis 3-5 money, Colla cornus cervi 3-5 money, charred Radix Sanguisorbae 3-5 money, Radix Angelicae Sinensis 3-5 money, Radix Dipsaci 3-5 money, Semen Astragali Complanati 3-5 money, Radix Rehmanniae Preparata 3-5 money, Radix Scrophulariae 3-5 money, Herba Cistanches 4-6 money.

2, according to the preparation method of the described medicine of claim 1, it is characterized in that:

A, Placenta Hominis powder are singly put standby for 0.8-1 liang;

B, Colla Plastri Testudinis 3-5 money, Colla Corii Asini 3-5 money, Colla cornus cervi 3-5 money are mixed put together, adds 3 liang of water, after heated and stirred was dissolved out, adding Crinis Carbonisatus 3-5 money were mixed thoroughly standby;

C, Rhizoma Atractylodis Macrocephalae charcoal 3-5 money, Fructus Schisandrae Chinensis 3-5 money, charred Radix Sanguisorbae 3-5 money, Radix Angelicae Sinensis 3-5 money, Radix Dipsaci 3-5 money, Semen Astragali Complanati 3-5 money, Radix Rehmanniae Preparata 3-5 money, Radix Scrophulariae 3-5 money, Herba Cistanches 4-6 money nine flavor medicines are put into drug-decocting pot add water, water did not have medicine, after opening with baked wheaten cake, boiling was fried in shallow oil 25-30 minutes, soup poured out puts into container, and then add water, with burn open after, boiling was fried in shallow oil 30-40 minutes, and the secondary decoction mixes and gets final product after frying in shallow oil.